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Editing gene: OSBPL3 (CAeditome ID:26031)

Gene summary for OSBPL3

Gene summary

Gene information	Gene symbol	OSBPL3
	Gene ID	26031
	Gene name	oxysterol binding protein like 3
	Synonyms	ORP-3\|ORP3\|OSBP3
	Cytomap	7p15.3
	Type of gene	protein-coding
	Description	oxysterol-binding protein-related protein 3OSBP-related protein 3
	Modification date	20210518
	UniProtAcc	Q9H4L5
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
OSBPL3	GO:0015485	Oxysterol-binding protein-related protein 3	17428193
OSBPL3	GO:0005829	Oxysterol-binding protein-related protein 3	14593528
OSBPL3	GO:0005886	Oxysterol-binding protein-related protein 3	14593528
OSBPL3	GO:0031965	Oxysterol-binding protein-related protein 3	14593528
OSBPL3	GO:0097038	Oxysterol-binding protein-related protein 3	14593528

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RNA A-to-I events for OSBPL3

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000070882.11

RNA A-to-I editing events in Cancer.

CAediting_532608(24800511, -), CAediting_532609(24800519, -), CAediting_532610(24800524, -), CAediting_532611(24800525, -), CAediting_532612(24800545, -), CAediting_532613(24800563, -), CAediting_532614(24800565, -), CAediting_532615(24800585, -), CAediting_532616(24800595, -), CAediting_532617(24800630, -), CAediting_532618(24800632, -), CAediting_532619(24800633, -), CAediting_532620(24800634, -), CAediting_532621(24800635, -), CAediting_532622(24800639, -), CAediting_532623(24800650, -), CAediting_532624(24800661, -), CAediting_532625(24800665, -), CAediting_532626(24800684, -), CAediting_532627(24800721, -), CAediting_532628(24800724, -), CAediting_532629(24800729, -), CAediting_532630(24800730, -), CAediting_532631(24800986, -), CAediting_532632(24800995, -), CAediting_532633(24800998, -), CAediting_532634(24801037, -), CAediting_532635(24801048, -), CAediting_532636(24801049, -), CAediting_532637(24801075, -), CAediting_532638(24801078, -), CAediting_532639(24801082, -), CAediting_532640(24801129, -), CAediting_532641(24801158, -), CAediting_532642(24801192, -), CAediting_532643(24806095, -), CAediting_532644(24808022, -), CAediting_532645(24808026, -), CAediting_532646(24808077, -), CAediting_532647(24808079, -), CAediting_532648(24808080, -), CAediting_532649(24813111, -), CAediting_532650(24813125, -), CAediting_532651(24828162, -), CAediting_532652(24828163, -), CAediting_532653(24828165, -), CAediting_532654(24828486, -), CAediting_532655(24828496, -), CAediting_532656(24833757, -), CAediting_532657(24836995, -), CAediting_532658(24837031, -), CAediting_532659(24837282, -), CAediting_532660(24837328, -), CAediting_532661(24837342, -), CAediting_532662(24837350, -), CAediting_532663(24837368, -), CAediting_532664(24837430, -), CAediting_532665(24837450, -), CAediting_532666(24838413, -), CAediting_532667(24839801, -), CAediting_532668(24839879, -), CAediting_532669(24849913, -), CAediting_532670(24866579, -), CAediting_532671(24896889, -), CAediting_532672(24904197, -), CAediting_532673(24905860, -), CAediting_532674(24905950, -), CAediting_532675(24905954, -), CAediting_532676(24906022, -), CAediting_532677(24909890, -), CAediting_532678(24909901, -), CAediting_532679(24909914, -), CAediting_532680(24909969, -), CAediting_532681(24909972, -), CAediting_532682(24909973, -), CAediting_532683(24910038, -), CAediting_532684(24910079, -), CAediting_532685(24930666, -), CAediting_532686(24930667, -), CAediting_532687(24940819, -), CAediting_532688(24970216, -), CAediting_532689(24980984, -),

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RNA editing positional annotations for OSBPL3 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_532608	chr7_24800511_-	ncRNA_intronic
CAediting_532609	chr7_24800519_-	ncRNA_intronic
CAediting_532610	chr7_24800524_-	ncRNA_intronic
CAediting_532611	chr7_24800525_-	ncRNA_intronic
CAediting_532612	chr7_24800545_-	ncRNA_intronic
CAediting_532613	chr7_24800563_-	ncRNA_intronic
CAediting_532614	chr7_24800565_-	ncRNA_intronic
CAediting_532615	chr7_24800585_-	ncRNA_intronic
CAediting_532616	chr7_24800595_-	ncRNA_intronic
CAediting_532617	chr7_24800630_-	ncRNA_intronic
CAediting_532618	chr7_24800632_-	ncRNA_intronic
CAediting_532619	chr7_24800633_-	ncRNA_intronic
CAediting_532620	chr7_24800634_-	ncRNA_intronic
CAediting_532621	chr7_24800635_-	ncRNA_intronic
CAediting_532622	chr7_24800639_-	ncRNA_intronic
CAediting_532623	chr7_24800650_-	ncRNA_intronic
CAediting_532624	chr7_24800661_-	ncRNA_intronic
CAediting_532625	chr7_24800665_-	ncRNA_intronic
CAediting_532626	chr7_24800684_-	ncRNA_intronic
CAediting_532627	chr7_24800721_-	ncRNA_intronic
CAediting_532628	chr7_24800724_-	ncRNA_intronic
CAediting_532629	chr7_24800729_-	ncRNA_intronic
CAediting_532630	chr7_24800730_-	ncRNA_intronic
CAediting_532631	chr7_24800986_-	ncRNA_intronic
CAediting_532632	chr7_24800995_-	ncRNA_intronic
CAediting_532633	chr7_24800998_-	ncRNA_intronic
CAediting_532634	chr7_24801037_-	ncRNA_intronic
CAediting_532635	chr7_24801048_-	ncRNA_intronic
CAediting_532636	chr7_24801049_-	ncRNA_intronic
CAediting_532637	chr7_24801075_-	ncRNA_intronic
CAediting_532638	chr7_24801078_-	ncRNA_intronic
CAediting_532639	chr7_24801082_-	ncRNA_intronic
CAediting_532640	chr7_24801129_-	ncRNA_intronic
CAediting_532641	chr7_24801158_-	ncRNA_intronic
CAediting_532642	chr7_24801192_-	ncRNA_intronic
CAediting_532643	chr7_24806095_-	ncRNA_intronic
CAediting_532644	chr7_24808022_-	ncRNA_intronic
CAediting_532645	chr7_24808026_-	ncRNA_intronic
CAediting_532646	chr7_24808077_-	ncRNA_intronic
CAediting_532647	chr7_24808079_-	ncRNA_intronic
CAediting_532648	chr7_24808080_-	ncRNA_intronic
CAediting_532649	chr7_24813111_-	ncRNA_intronic
CAediting_532650	chr7_24813125_-	ncRNA_intronic
CAediting_532651	chr7_24828162_-	intronic
CAediting_532652	chr7_24828163_-	intronic
CAediting_532653	chr7_24828165_-	intronic
CAediting_532654	chr7_24828486_-	intronic
CAediting_532655	chr7_24828496_-	intronic
CAediting_532656	chr7_24833757_-	intronic
CAediting_532657	chr7_24836995_-	intronic
CAediting_532658	chr7_24837031_-	intronic
CAediting_532659	chr7_24837282_-	intronic
CAediting_532660	chr7_24837328_-	intronic
CAediting_532661	chr7_24837342_-	intronic
CAediting_532662	chr7_24837350_-	intronic
CAediting_532663	chr7_24837368_-	intronic
CAediting_532664	chr7_24837430_-	intronic
CAediting_532665	chr7_24837450_-	intronic
CAediting_532666	chr7_24838413_-	intronic
CAediting_532667	chr7_24839801_-	intronic
CAediting_532668	chr7_24839879_-	intronic
CAediting_532669	chr7_24849913_-	intronic
CAediting_532670	chr7_24866579_-	intronic
CAediting_532671	chr7_24896889_-	intronic
CAediting_532672	chr7_24904197_-	intronic
CAediting_532673	chr7_24905860_-	intronic
CAediting_532674	chr7_24905950_-	intronic
CAediting_532675	chr7_24905954_-	intronic
CAediting_532676	chr7_24906022_-	intronic
CAediting_532677	chr7_24909890_-	intronic
CAediting_532678	chr7_24909901_-	intronic
CAediting_532679	chr7_24909914_-	intronic
CAediting_532680	chr7_24909969_-	intronic
CAediting_532681	chr7_24909972_-	intronic
CAediting_532682	chr7_24909973_-	intronic
CAediting_532683	chr7_24910038_-	intronic
CAediting_532684	chr7_24910079_-	intronic
CAediting_532685	chr7_24930666_-	intronic
CAediting_532686	chr7_24930667_-	intronic
CAediting_532687	chr7_24940819_-	intronic
CAediting_532688	chr7_24970216_-	intronic
CAediting_532689	chr7_24980984_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_532608	chr7_24800511_-	SINE	Alu	AluSx
CAediting_532609	chr7_24800519_-	SINE	Alu	AluSx
CAediting_532610	chr7_24800524_-	SINE	Alu	AluSx
CAediting_532611	chr7_24800525_-	SINE	Alu	AluSx
CAediting_532612	chr7_24800545_-	SINE	Alu	AluSx
CAediting_532613	chr7_24800563_-	SINE	Alu	AluSx
CAediting_532614	chr7_24800565_-	SINE	Alu	AluSx
CAediting_532615	chr7_24800585_-	SINE	Alu	AluSx
CAediting_532616	chr7_24800595_-	SINE	Alu	AluSx
CAediting_532617	chr7_24800630_-	SINE	Alu	AluSx
CAediting_532618	chr7_24800632_-	SINE	Alu	AluSx
CAediting_532619	chr7_24800633_-	SINE	Alu	AluSx
CAediting_532620	chr7_24800634_-	SINE	Alu	AluSx
CAediting_532621	chr7_24800635_-	SINE	Alu	AluSx
CAediting_532622	chr7_24800639_-	SINE	Alu	AluSx
CAediting_532623	chr7_24800650_-	SINE	Alu	AluSx
CAediting_532624	chr7_24800661_-	SINE	Alu	AluSx
CAediting_532625	chr7_24800665_-	SINE	Alu	AluSx
CAediting_532626	chr7_24800684_-	SINE	Alu	AluSx
CAediting_532627	chr7_24800721_-	SINE	Alu	AluSx
CAediting_532628	chr7_24800724_-	SINE	Alu	AluSx
CAediting_532629	chr7_24800729_-	SINE	Alu	AluSx
CAediting_532630	chr7_24800730_-	SINE	Alu	AluSx
CAediting_532631	chr7_24800986_-	SINE	Alu	AluSg
CAediting_532632	chr7_24800995_-	SINE	Alu	AluSg
CAediting_532633	chr7_24800998_-	SINE	Alu	AluSg
CAediting_532634	chr7_24801037_-	SINE	Alu	AluSg
CAediting_532635	chr7_24801048_-	SINE	Alu	AluSg
CAediting_532636	chr7_24801049_-	SINE	Alu	AluSg
CAediting_532637	chr7_24801075_-	SINE	Alu	AluSg
CAediting_532638	chr7_24801078_-	SINE	Alu	AluSg
CAediting_532639	chr7_24801082_-	SINE	Alu	AluSg
CAediting_532640	chr7_24801129_-	SINE	Alu	AluSg
CAediting_532641	chr7_24801158_-	SINE	Alu	AluSg
CAediting_532642	chr7_24801192_-	SINE	Alu	AluSg
CAediting_532643	chr7_24806095_-	SINE	Alu	AluSz6
CAediting_532644	chr7_24808022_-	SINE	Alu	AluSz6
CAediting_532645	chr7_24808026_-	SINE	Alu	AluSz6
CAediting_532646	chr7_24808077_-	SINE	Alu	AluSz6
CAediting_532647	chr7_24808079_-	SINE	Alu	AluSz6
CAediting_532648	chr7_24808080_-	SINE	Alu	AluSz6
CAediting_532649	chr7_24813111_-	SINE	Alu	AluJr
CAediting_532650	chr7_24813125_-	SINE	Alu	AluJr
CAediting_532651	chr7_24828162_-	SINE	Alu	AluSz
CAediting_532652	chr7_24828163_-	SINE	Alu	AluSz
CAediting_532653	chr7_24828165_-	SINE	Alu	AluSz
CAediting_532654	chr7_24828486_-	SINE	Alu	AluSx
CAediting_532655	chr7_24828496_-	SINE	Alu	AluSx
CAediting_532657	chr7_24836995_-	SINE	Alu	AluJb
CAediting_532658	chr7_24837031_-	SINE	Alu	AluJb
CAediting_532659	chr7_24837282_-	SINE	Alu	AluJr
CAediting_532660	chr7_24837328_-	SINE	Alu	AluJr
CAediting_532661	chr7_24837342_-	SINE	Alu	AluJr
CAediting_532662	chr7_24837350_-	SINE	Alu	AluJr
CAediting_532663	chr7_24837368_-	SINE	Alu	AluJr
CAediting_532664	chr7_24837430_-	SINE	Alu	AluJr
CAediting_532665	chr7_24837450_-	SINE	Alu	AluJr
CAediting_532666	chr7_24838413_-	SINE	Alu	AluSz6
CAediting_532667	chr7_24839801_-	SINE	Alu	AluSz
CAediting_532668	chr7_24839879_-	SINE	Alu	AluSz
CAediting_532669	chr7_24849913_-	SINE	Alu	AluSz
CAediting_532670	chr7_24866579_-	SINE	Alu	AluJb
CAediting_532671	chr7_24896889_-	SINE	Alu	AluSz
CAediting_532673	chr7_24905860_-	SINE	Alu	AluSx1
CAediting_532674	chr7_24905950_-	SINE	Alu	AluSx1
CAediting_532675	chr7_24905954_-	SINE	Alu	AluSx1
CAediting_532676	chr7_24906022_-	SINE	Alu	AluSx1
CAediting_532677	chr7_24909890_-	SINE	Alu	AluSx
CAediting_532678	chr7_24909901_-	SINE	Alu	AluSx
CAediting_532679	chr7_24909914_-	SINE	Alu	AluSx
CAediting_532680	chr7_24909969_-	SINE	Alu	AluSx
CAediting_532681	chr7_24909972_-	SINE	Alu	AluSx
CAediting_532682	chr7_24909973_-	SINE	Alu	AluSx
CAediting_532683	chr7_24910038_-	SINE	Alu	AluSx
CAediting_532684	chr7_24910079_-	SINE	Alu	AluSx
CAediting_532685	chr7_24930666_-	DNA	hAT-Charlie	Charlie4z
CAediting_532686	chr7_24930667_-	DNA	hAT-Charlie	Charlie4z
CAediting_532687	chr7_24940819_-	SINE	Alu	AluY
CAediting_532688	chr7_24970216_-	SINE	Alu	AluSx1

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RNA A-to-I editing events in the alternative splicing sites for OSBPL3

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000070882.11.OSBPL3.

Correlation between RNA A-to-I editing and PSI for ENSG00000070882.11.OSBPL3.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for OSBPL3

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for OSBPL3

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for OSBPL3

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for OSBPL3

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for OSBPL3

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for OSBPL3

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for OSBPL3

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for OSBPL3

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for OSBPL3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene