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Center for Computational Systems Medicine
Soverview

Gene summary

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RNA A-to-I events

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Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

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Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

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Relation with ADAR

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Relation with cancer stages

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Relation with survival state

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Related drugs with this gene

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Related diseases with this gene

Editing gene: NIPSNAP3A (CAeditome ID:25934)

Gene summary for NIPSNAP3A

check button Gene summary
Gene informationGene symbol

NIPSNAP3A

Gene ID

25934

Gene namenipsnap homolog 3A
SynonymsHSPC299|NIPSNAP4|TASSC
Cytomap

9q31.1

Type of geneprotein-coding
Descriptionprotein NipSnap homolog 3Aprotein NipSnap homolog 4target for Salmonella secreted protein C
Modification date20210518
UniProtAcc

Q9UFN0

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for NIPSNAP3A

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000136783.9

check button RNA A-to-I editing events in Cancer.
CAediting_699786(104751070, +), CAediting_699787(104751110, +), CAediting_699788(104755020, +), CAediting_699789(104755025, +), CAediting_699790(104755075, +), CAediting_699791(104755078, +), CAediting_699792(104755079, +), CAediting_699793(104755084, +), CAediting_699794(104755130, +), CAediting_699795(104755153, +), CAediting_699796(104755798, +), CAediting_699797(104755857, +), CAediting_699798(104756884, +), CAediting_699799(104757057, +), CAediting_699800(104757823, +), CAediting_699801(104758799, +), CAediting_699802(104758808, +), CAediting_699803(104758849, +), CAediting_699804(104758850, +), CAediting_699805(104758902, +), CAediting_699806(104758945, +),

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RNA editing positional annotations for NIPSNAP3A using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred
CAediting_699786chr9_104751070_+nonsynonymous SNVENST00000374767.4c.A175Gp.N59DTBD
CAediting_699787chr9_104751110_+nonsynonymous SNVENST00000374767.4c.A215Gp.Y72CDDD

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_699786chr9_104751070_+exonic
CAediting_699787chr9_104751110_+exonic
CAediting_699788chr9_104755020_+ncRNA_intronic
CAediting_699789chr9_104755025_+ncRNA_intronic
CAediting_699790chr9_104755075_+ncRNA_intronic
CAediting_699791chr9_104755078_+ncRNA_intronic
CAediting_699792chr9_104755079_+ncRNA_intronic
CAediting_699793chr9_104755084_+ncRNA_intronic
CAediting_699794chr9_104755130_+ncRNA_intronic
CAediting_699795chr9_104755153_+ncRNA_intronic
CAediting_699796chr9_104755798_+ncRNA_intronic
CAediting_699797chr9_104755857_+ncRNA_intronic
CAediting_699798chr9_104756884_+ncRNA_intronic
CAediting_699799chr9_104757057_+ncRNA_intronic
CAediting_699800chr9_104757823_+ncRNA_intronic
CAediting_699801chr9_104758799_+ncRNA_intronic
CAediting_699802chr9_104758808_+ncRNA_intronic
CAediting_699803chr9_104758849_+ncRNA_intronic
CAediting_699804chr9_104758850_+ncRNA_intronic
CAediting_699805chr9_104758902_+ncRNA_intronic
CAediting_699806chr9_104758945_+ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_699788chr9_104755020_+SINEAluAluSq2
CAediting_699789chr9_104755025_+SINEAluAluSq2
CAediting_699790chr9_104755075_+SINEAluAluSq2
CAediting_699791chr9_104755078_+SINEAluAluSq2
CAediting_699792chr9_104755079_+SINEAluAluSq2
CAediting_699793chr9_104755084_+SINEAluAluSq2
CAediting_699794chr9_104755130_+SINEAluAluSq2
CAediting_699795chr9_104755153_+SINEAluAluSq2
CAediting_699796chr9_104755798_+SINEAluAluJr4
CAediting_699797chr9_104755857_+SINEAluAluJr4
CAediting_699798chr9_104756884_+SINEAluAluSx
CAediting_699799chr9_104757057_+SINEAluAluSx
CAediting_699800chr9_104757823_+SINEAluAluJr
CAediting_699801chr9_104758799_+SINEAluAluSq2
CAediting_699802chr9_104758808_+SINEAluAluSq2
CAediting_699803chr9_104758849_+SINEAluAluSq2
CAediting_699804chr9_104758850_+SINEAluAluSq2
CAediting_699805chr9_104758902_+SINEAluAluSq2
CAediting_699806chr9_104758945_+SINEAluAluSq2

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RNA A-to-I editing events in the alternative splicing sites for NIPSNAP3A

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000136783.9.NIPSNAP3A.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000136783.9.NIPSNAP3A.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for NIPSNAP3A

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for NIPSNAP3A

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.
all structure


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The effects of the RNA editing to the miRNA binding sites for NIPSNAP3A

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for NIPSNAP3A

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for NIPSNAP3A

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for NIPSNAP3A

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for NIPSNAP3A

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for NIPSNAP3A

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for NIPSNAP3A

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource