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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: GABBR1 (CAeditome ID:2550)

Gene summary for GABBR1

check button Gene summary
Gene informationGene symbol

GABBR1

Gene ID

2550

Gene namegamma-aminobutyric acid type B receptor subunit 1
SynonymsGABABR1|GABBR1-3|GB1|GPRC3A
Cytomap

6p22.1

Type of geneprotein-coding
Descriptiongamma-aminobutyric acid type B receptor subunit 1GABA-B receptor, R1 subunitgamma-aminobutyric acid (GABA) B receptor, 1seven transmembrane helix receptor
Modification date20210518
UniProtAcc

Q9UBS5

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
GABBR1

GO:0004965

Gamma-aminobutyric acid type B receptor subunit 1

9872316

GABBR1

GO:0004965

Gamma-aminobutyric acid type B receptor subunit 1

10328880

GABBR1

GO:0007193

Gamma-aminobutyric acid type B receptor subunit 1

10328880

GABBR1

GO:0007214

Gamma-aminobutyric acid type B receptor subunit 1

9872316

GABBR1

GO:0005887

Gamma-aminobutyric acid type B receptor subunit 1

9872316


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RNA A-to-I events for GABBR1

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000204681.9

check button RNA A-to-I editing events in Cancer.
CAediting_467108(29591029, -), CAediting_467109(29591030, -), CAediting_467110(29591067, -), CAediting_467111(29591080, -), CAediting_467112(29591089, -), CAediting_467113(29591092, -), CAediting_467114(29591106, -), CAediting_467115(29591109, -), CAediting_467116(29591129, -), CAediting_467117(29591155, -), CAediting_467118(29591165, -), CAediting_467119(29591168, -), CAediting_467120(29591169, -), CAediting_467121(29591177, -), CAediting_467122(29591192, -), CAediting_467123(29591205, -), CAediting_467124(29591211, -), CAediting_467125(29591254, -), CAediting_467126(29591266, -), CAediting_467127(29592424, -), CAediting_467128(29592451, -), CAediting_467129(29592503, -), CAediting_467130(29592504, -), CAediting_467131(29592577, -), CAediting_467132(29592578, -), CAediting_467133(29592586, -), CAediting_467134(29592597, -), CAediting_467135(29592708, -), CAediting_467136(29592720, -), CAediting_467137(29592721, -), CAediting_467138(29592722, -), CAediting_467139(29592771, -), CAediting_467140(29592793, -), CAediting_467141(29592849, -), CAediting_467142(29592853, -), CAediting_467143(29592902, -), CAediting_467144(29592963, -), CAediting_467145(29593075, -), CAediting_467146(29593076, -), CAediting_467147(29593084, -), CAediting_467148(29593103, -), CAediting_467149(29593156, -), CAediting_467150(29593161, -), CAediting_467151(29593167, -), CAediting_467152(29593170, -), CAediting_467153(29593174, -), CAediting_467154(29593178, -), CAediting_467155(29593184, -), CAediting_467156(29593210, -), CAediting_467157(29593214, -), CAediting_467158(29593245, -), CAediting_467159(29593249, -), CAediting_467160(29593273, -), CAediting_467161(29593310, -), CAediting_467162(29593313, -), CAediting_467163(29593327, -), CAediting_467164(29595467, -), CAediting_467165(29595536, -), CAediting_467166(29595612, -), CAediting_467167(29595810, -), CAediting_467168(29595989, -), CAediting_467169(29596992, -), CAediting_467170(29597011, -), CAediting_467171(29597014, -), CAediting_467172(29597066, -), CAediting_467173(29597164, -), CAediting_467174(29598083, -), CAediting_467175(29598098, -), CAediting_467176(29598102, -), CAediting_467177(29598115, -), CAediting_467178(29598124, -), CAediting_467179(29598135, -), CAediting_467180(29598213, -), CAediting_467181(29598259, -), CAediting_467182(29598260, -), CAediting_467183(29600929, -), CAediting_467184(29600981, -), CAediting_467185(29600985, -), CAediting_467186(29600999, -), CAediting_467187(29601016, -), CAediting_467188(29601025, -), CAediting_467189(29601026, -), CAediting_467190(29601081, -), CAediting_467191(29601089, -), CAediting_467192(29601158, -), CAediting_467193(29601159, -), CAediting_467194(29601167, -), CAediting_467195(29615035, -), CAediting_467196(29615160, -), CAediting_467197(29615223, -), CAediting_467198(29615240, -), CAediting_467199(29617370, -), CAediting_467200(29617387, -), CAediting_467201(29617410, -), CAediting_467202(29617439, -), CAediting_467203(29617440, -), CAediting_467204(29617478, -), CAediting_467205(29617480, -), CAediting_467206(29617497, -),

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RNA editing positional annotations for GABBR1 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_467108chr6_29591029_-intronic
CAediting_467109chr6_29591030_-intronic
CAediting_467110chr6_29591067_-intronic
CAediting_467111chr6_29591080_-intronic
CAediting_467112chr6_29591089_-intronic
CAediting_467113chr6_29591092_-intronic
CAediting_467114chr6_29591106_-intronic
CAediting_467115chr6_29591109_-intronic
CAediting_467116chr6_29591129_-intronic
CAediting_467117chr6_29591155_-intronic
CAediting_467118chr6_29591165_-intronic
CAediting_467119chr6_29591168_-intronic
CAediting_467120chr6_29591169_-intronic
CAediting_467121chr6_29591177_-intronic
CAediting_467122chr6_29591192_-intronic
CAediting_467123chr6_29591205_-intronic
CAediting_467124chr6_29591211_-intronic
CAediting_467125chr6_29591254_-intronic
CAediting_467126chr6_29591266_-intronic
CAediting_467127chr6_29592424_-intronic
CAediting_467128chr6_29592451_-intronic
CAediting_467129chr6_29592503_-intronic
CAediting_467130chr6_29592504_-intronic
CAediting_467131chr6_29592577_-intronic
CAediting_467132chr6_29592578_-intronic
CAediting_467133chr6_29592586_-intronic
CAediting_467134chr6_29592597_-intronic
CAediting_467135chr6_29592708_-intronic
CAediting_467136chr6_29592720_-intronic
CAediting_467137chr6_29592721_-intronic
CAediting_467138chr6_29592722_-intronic
CAediting_467139chr6_29592771_-intronic
CAediting_467140chr6_29592793_-intronic
CAediting_467141chr6_29592849_-intronic
CAediting_467142chr6_29592853_-intronic
CAediting_467143chr6_29592902_-intronic
CAediting_467144chr6_29592963_-intronic
CAediting_467145chr6_29593075_-intronic
CAediting_467146chr6_29593076_-intronic
CAediting_467147chr6_29593084_-intronic
CAediting_467148chr6_29593103_-intronic
CAediting_467149chr6_29593156_-intronic
CAediting_467150chr6_29593161_-intronic
CAediting_467151chr6_29593167_-intronic
CAediting_467152chr6_29593170_-intronic
CAediting_467153chr6_29593174_-intronic
CAediting_467154chr6_29593178_-intronic
CAediting_467155chr6_29593184_-intronic
CAediting_467156chr6_29593210_-intronic
CAediting_467157chr6_29593214_-intronic
CAediting_467158chr6_29593245_-intronic
CAediting_467159chr6_29593249_-intronic
CAediting_467160chr6_29593273_-intronic
CAediting_467161chr6_29593310_-intronic
CAediting_467162chr6_29593313_-intronic
CAediting_467163chr6_29593327_-intronic
CAediting_467164chr6_29595467_-intronic
CAediting_467165chr6_29595536_-intronic
CAediting_467166chr6_29595612_-intronic
CAediting_467167chr6_29595810_-intronic
CAediting_467168chr6_29595989_-intronic
CAediting_467169chr6_29596992_-intronic
CAediting_467170chr6_29597011_-intronic
CAediting_467171chr6_29597014_-intronic
CAediting_467172chr6_29597066_-intronic
CAediting_467173chr6_29597164_-intronic
CAediting_467174chr6_29598083_-intronic
CAediting_467175chr6_29598098_-intronic
CAediting_467176chr6_29598102_-intronic
CAediting_467177chr6_29598115_-intronic
CAediting_467178chr6_29598124_-intronic
CAediting_467179chr6_29598135_-intronic
CAediting_467180chr6_29598213_-intronic
CAediting_467181chr6_29598259_-intronic
CAediting_467182chr6_29598260_-intronic
CAediting_467183chr6_29600929_-intronic
CAediting_467184chr6_29600981_-intronic
CAediting_467185chr6_29600985_-intronic
CAediting_467186chr6_29600999_-intronic
CAediting_467187chr6_29601016_-intronic
CAediting_467188chr6_29601025_-intronic
CAediting_467189chr6_29601026_-intronic
CAediting_467190chr6_29601081_-intronic
CAediting_467191chr6_29601089_-intronic
CAediting_467192chr6_29601158_-intronic
CAediting_467193chr6_29601159_-intronic
CAediting_467194chr6_29601167_-intronic
CAediting_467195chr6_29615035_-ncRNA_intronic
CAediting_467196chr6_29615160_-ncRNA_intronic
CAediting_467197chr6_29615223_-ncRNA_intronic
CAediting_467198chr6_29615240_-ncRNA_intronic
CAediting_467199chr6_29617370_-ncRNA_intronic
CAediting_467200chr6_29617387_-ncRNA_intronic
CAediting_467201chr6_29617410_-ncRNA_intronic
CAediting_467202chr6_29617439_-ncRNA_intronic
CAediting_467203chr6_29617440_-ncRNA_intronic
CAediting_467204chr6_29617478_-ncRNA_intronic
CAediting_467205chr6_29617480_-ncRNA_intronic
CAediting_467206chr6_29617497_-ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_467108chr6_29591029_-SINEAluAluSx3
CAediting_467109chr6_29591030_-SINEAluAluSx3
CAediting_467110chr6_29591067_-SINEAluAluSx3
CAediting_467111chr6_29591080_-SINEAluAluSx3
CAediting_467112chr6_29591089_-SINEAluAluSx3
CAediting_467113chr6_29591092_-SINEAluAluSx3
CAediting_467114chr6_29591106_-SINEAluAluSx3
CAediting_467115chr6_29591109_-SINEAluAluSx3
CAediting_467116chr6_29591129_-SINEAluAluSx3
CAediting_467117chr6_29591155_-SINEAluAluSx3
CAediting_467118chr6_29591165_-SINEAluAluSx3
CAediting_467119chr6_29591168_-SINEAluAluSx3
CAediting_467120chr6_29591169_-SINEAluAluSx3
CAediting_467121chr6_29591177_-SINEAluAluSx3
CAediting_467122chr6_29591192_-SINEAluAluSx3
CAediting_467123chr6_29591205_-SINEAluAluSx3
CAediting_467124chr6_29591211_-SINEAluAluSx3
CAediting_467125chr6_29591254_-SINEAluAluSx3
CAediting_467126chr6_29591266_-SINEAluAluSx3
CAediting_467127chr6_29592424_-SINEAluAluJr4
CAediting_467128chr6_29592451_-SINEAluAluJr4
CAediting_467129chr6_29592503_-SINEAluAluJr4
CAediting_467130chr6_29592504_-SINEAluAluJr4
CAediting_467131chr6_29592577_-SINEAluAluJr4
CAediting_467132chr6_29592578_-SINEAluAluJr4
CAediting_467133chr6_29592586_-SINEAluAluJr4
CAediting_467134chr6_29592597_-SINEAluAluJr4
CAediting_467135chr6_29592708_-SINEAluAluY
CAediting_467136chr6_29592720_-SINEAluAluY
CAediting_467137chr6_29592721_-SINEAluAluY
CAediting_467138chr6_29592722_-SINEAluAluY
CAediting_467139chr6_29592771_-SINEAluAluY
CAediting_467140chr6_29592793_-SINEAluAluY
CAediting_467141chr6_29592849_-SINEAluAluY
CAediting_467142chr6_29592853_-SINEAluAluY
CAediting_467143chr6_29592902_-SINEAluAluY
CAediting_467144chr6_29592963_-SINEAluAluY
CAediting_467145chr6_29593075_-SINEAluAluJb
CAediting_467146chr6_29593076_-SINEAluAluJb
CAediting_467147chr6_29593084_-SINEAluAluJb
CAediting_467148chr6_29593103_-SINEAluAluJb
CAediting_467149chr6_29593156_-SINEAluAluJb
CAediting_467150chr6_29593161_-SINEAluAluJb
CAediting_467151chr6_29593167_-SINEAluAluJb
CAediting_467152chr6_29593170_-SINEAluAluJb
CAediting_467153chr6_29593174_-SINEAluAluJb
CAediting_467154chr6_29593178_-SINEAluAluJb
CAediting_467155chr6_29593184_-SINEAluAluJb
CAediting_467156chr6_29593210_-SINEAluAluJb
CAediting_467157chr6_29593214_-SINEAluAluJb
CAediting_467158chr6_29593245_-SINEAluAluJb
CAediting_467159chr6_29593249_-SINEAluAluJb
CAediting_467160chr6_29593273_-SINEAluAluJb
CAediting_467161chr6_29593310_-SINEAluAluJb
CAediting_467162chr6_29593313_-SINEAluAluJb
CAediting_467163chr6_29593327_-SINEAluAluJb
CAediting_467164chr6_29595467_-SINEAluAluJb
CAediting_467165chr6_29595536_-SINEAluAluJb
CAediting_467166chr6_29595612_-SINEAluAluJb
CAediting_467167chr6_29595810_-SINEAluAluSc8
CAediting_467168chr6_29595989_-SINEAluAluSc8
CAediting_467169chr6_29596992_-SINEAluAluJb
CAediting_467170chr6_29597011_-SINEAluAluJb
CAediting_467171chr6_29597014_-SINEAluAluJb
CAediting_467172chr6_29597066_-SINEAluAluJb
CAediting_467173chr6_29597164_-SINEAluAluJb
CAediting_467174chr6_29598083_-SINEAluAluSx1
CAediting_467175chr6_29598098_-SINEAluAluSx1
CAediting_467176chr6_29598102_-SINEAluAluSx1
CAediting_467177chr6_29598115_-SINEAluAluSx1
CAediting_467178chr6_29598124_-SINEAluAluSx1
CAediting_467179chr6_29598135_-SINEAluAluSx1
CAediting_467180chr6_29598213_-SINEAluAluSx1
CAediting_467181chr6_29598259_-SINEAluAluSx1
CAediting_467182chr6_29598260_-SINEAluAluSx1
CAediting_467183chr6_29600929_-SINEAluAluSg7
CAediting_467184chr6_29600981_-SINEAluAluSg7
CAediting_467185chr6_29600985_-SINEAluAluSg7
CAediting_467186chr6_29600999_-SINEAluAluSg7
CAediting_467187chr6_29601016_-SINEAluAluSg7
CAediting_467188chr6_29601025_-SINEAluAluSg7
CAediting_467189chr6_29601026_-SINEAluAluSg7
CAediting_467190chr6_29601081_-SINEAluAluSg7
CAediting_467191chr6_29601089_-SINEAluAluSg7
CAediting_467192chr6_29601158_-SINEAluAluSg7
CAediting_467193chr6_29601159_-SINEAluAluSg7
CAediting_467194chr6_29601167_-SINEAluAluSg7
CAediting_467195chr6_29615035_-SINEAluAluSx3
CAediting_467196chr6_29615160_-SINEAluAluSx3
CAediting_467197chr6_29615223_-SINEAluAluSx3
CAediting_467198chr6_29615240_-SINEAluAluSx3
CAediting_467199chr6_29617370_-SINEAluAluSg
CAediting_467200chr6_29617387_-SINEAluAluSg
CAediting_467201chr6_29617410_-SINEAluAluSg
CAediting_467202chr6_29617439_-SINEAluAluSg
CAediting_467203chr6_29617440_-SINEAluAluSg
CAediting_467204chr6_29617478_-SINEAluAluSg
CAediting_467205chr6_29617480_-SINEAluAluSg
CAediting_467206chr6_29617497_-SINEAluAluSg

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RNA A-to-I editing events in the alternative splicing sites for GABBR1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000204681.9.GABBR1.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000204681.9.GABBR1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for GABBR1

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
LGG.CAediting_467108.ENSG00000204681.GABBR1.png
Soverview
LGG.CAediting_467125.ENSG00000204681.GABBR1.png
Soverview
LGG.CAediting_467131.ENSG00000204681.GABBR1.png
Soverview
LGG.CAediting_467143.ENSG00000204681.GABBR1.png
Soverview
LGG.CAediting_467145.ENSG00000204681.GABBR1.png
Soverview

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Protein coding region RNA A-to-I editings for GABBR1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for GABBR1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_393chr1_1167164_+ENSG00000204681.9ENST00000472823hsa-miR-200b-3p29621110296211167mer-m82962110929621129160-17.19
CAediting_393chr1_1167164_+ENSG00000204681.9ENST00000491829hsa-miR-200b-3p29621110296211167mer-m82962110929621129160-17.19
CAediting_1368054chr19_46709310_-ENSG00000204681.9ENST00000355973hsa-miR-320e29556045295560528mer-1a2955604529556062143-16.25
CAediting_604450chr7_133034877_-ENSG00000204681.9ENST00000355973hsa-miR-365429556048295560547mer-m82955604729556065140-15.43
CAediting_1368054chr19_46709310_-ENSG00000204681.9ENST00000472823hsa-miR-320e29623455296234617mer-1a2962345529623472143-16.76
CAediting_228905chr2_188297554_+ENSG00000204681.9ENST00000472823hsa-miR-561-3p29623367296233737mer-m82962336629623387142-7.36
CAediting_1229415chr17_67471547_+ENSG00000204681.9ENST00000472823hsa-miR-548aa29608670296086778mer-1a2960867029608694140-11.88
CAediting_77128chr1_85133844_+ENSG00000204681.9ENST00000472823hsa-miR-4423-3p29604861296048688mer-1a2960486129604880163-20.02
CAediting_604450chr7_133034877_-ENSG00000204681.9ENST00000472823hsa-miR-365429604944296049507mer-m82960494329604961149-20.71
CAediting_1306323chr19_13836462_-ENSG00000204681.9ENST00000472823hsa-miR-27a-3p29604515296045228mer-1a2960451529604535140-22.73
CAediting_86358chr1_109598906_+ENSG00000204681.9ENST00000472823hsa-miR-197-5p29603123296031297mer-m82960312229603144171-28.97
CAediting_77128chr1_85133844_+ENSG00000204681.9ENST00000472823hsa-miR-4423-3p29602922296029287mer-m82960292129602941140-12.89
CAediting_604450chr7_133034877_-ENSG00000204681.9ENST00000472823hsa-miR-365429603153296031608mer-1a2960315329603173155-21.17
CAediting_524911chr7_5495852_-ENSG00000204681.9ENST00000472823hsa-miR-589-3p29603166296031727mer-m82960316529603189151-15.16
CAediting_524911chr7_5495852_-ENSG00000204681.9ENST00000472823hsa-miR-589-3p29602972296029787mer-m82960297129602994152-13.99
CAediting_86358chr1_109598906_+ENSG00000204681.9ENST00000377016hsa-miR-197-5p29603123296031297mer-m82960312229603144171-28.97
CAediting_77128chr1_85133844_+ENSG00000204681.9ENST00000377016hsa-miR-4423-3p29602922296029287mer-m82960292129602941140-12.89
CAediting_604450chr7_133034877_-ENSG00000204681.9ENST00000377016hsa-miR-365429603153296031608mer-1a2960315329603173155-21.17
CAediting_524911chr7_5495852_-ENSG00000204681.9ENST00000377016hsa-miR-589-3p29603166296031727mer-m82960316529603189151-15.16
CAediting_524911chr7_5495852_-ENSG00000204681.9ENST00000377016hsa-miR-589-3p29602972296029787mer-m82960297129602994152-13.99
CAediting_86358chr1_109598906_+ENSG00000204681.9ENST00000377012hsa-miR-197-5p29603123296031297mer-m82960312229603144171-28.97
CAediting_77128chr1_85133844_+ENSG00000204681.9ENST00000377012hsa-miR-4423-3p29602922296029287mer-m82960292129602941140-12.89
CAediting_604450chr7_133034877_-ENSG00000204681.9ENST00000377012hsa-miR-365429603153296031608mer-1a2960315329603173155-21.17
CAediting_524911chr7_5495852_-ENSG00000204681.9ENST00000377012hsa-miR-589-3p29603166296031727mer-m82960316529603189151-15.16
CAediting_524911chr7_5495852_-ENSG00000204681.9ENST00000377012hsa-miR-589-3p29602972296029787mer-m82960297129602994152-13.99
CAediting_1368054chr19_46709310_-ENSG00000204681.9ENST00000491829hsa-miR-320e29623455296234617mer-1a2962345529623472143-16.76
CAediting_228905chr2_188297554_+ENSG00000204681.9ENST00000491829hsa-miR-561-3p29623367296233737mer-m82962336629623387142-7.36
CAediting_228905chr2_188297554_+ENSG00000204681.9ENST00000491829hsa-miR-561-3p29609314296093207mer-m82960931329609334144-12.53
CAediting_1229415chr17_67471547_+ENSG00000204681.9ENST00000491829hsa-miR-548aa29608670296086778mer-1a2960867029608694140-11.88
CAediting_77128chr1_85133844_+ENSG00000204681.9ENST00000491829hsa-miR-4423-3p29604861296048688mer-1a2960486129604880163-20.02
CAediting_604450chr7_133034877_-ENSG00000204681.9ENST00000491829hsa-miR-365429604944296049507mer-m82960494329604961149-20.71
CAediting_1306323chr19_13836462_-ENSG00000204681.9ENST00000491829hsa-miR-27a-3p29604515296045228mer-1a2960451529604535140-22.73
CAediting_86358chr1_109598906_+ENSG00000204681.9ENST00000491829hsa-miR-197-5p29603123296031297mer-m82960312229603144171-28.97
CAediting_77128chr1_85133844_+ENSG00000204681.9ENST00000491829hsa-miR-4423-3p29602922296029287mer-m82960292129602941140-12.89
CAediting_604450chr7_133034877_-ENSG00000204681.9ENST00000491829hsa-miR-365429603153296031608mer-1a2960315329603173155-21.17
CAediting_524911chr7_5495852_-ENSG00000204681.9ENST00000491829hsa-miR-589-3p29603166296031727mer-m82960316529603189151-15.16
CAediting_524911chr7_5495852_-ENSG00000204681.9ENST00000491829hsa-miR-589-3p29602972296029787mer-m82960297129602994152-13.99
CAediting_86358chr1_109598906_+ENSG00000204681.9ENST00000377034hsa-miR-197-5p29603123296031297mer-m82960312229603144171-28.97
CAediting_77128chr1_85133844_+ENSG00000204681.9ENST00000377034hsa-miR-4423-3p29602922296029287mer-m82960292129602941140-12.89
CAediting_604450chr7_133034877_-ENSG00000204681.9ENST00000377034hsa-miR-365429603153296031608mer-1a2960315329603173155-21.17
CAediting_524911chr7_5495852_-ENSG00000204681.9ENST00000377034hsa-miR-589-3p29603166296031727mer-m82960316529603189151-15.16
CAediting_524911chr7_5495852_-ENSG00000204681.9ENST00000377034hsa-miR-589-3p29602972296029787mer-m82960297129602994152-13.99
CAediting_1229415chr17_67471547_+ENSG00000204681.9ENST00000494877hsa-miR-548aa29608670296086778mer-1a2960867029608694140-11.88
CAediting_604450chr7_133034877_-ENSG00000204681.9ENST00000494877hsa-miR-365429604944296049507mer-m82960494329604961149-20.71
CAediting_1368054chr19_46709310_-ENSG00000204681.9ENST00000485508hsa-miR-320e29623455296234617mer-1a2962345529623472143-16.76
CAediting_228905chr2_188297554_+ENSG00000204681.9ENST00000485508hsa-miR-561-3p29623367296233737mer-m82962336629623387142-7.36
CAediting_468389chr6_31355314_-ENSG00000204681.9ENST00000355973hsa-miR-6891-5p29556066295560727mer-m82955606529556083142-17.52
CAediting_1524209chrX_134546392_-ENSG00000204681.9ENST00000472823hsa-miR-503-5p29629109296291157mer-1a2962910929629130145-23.9
CAediting_468389chr6_31355314_-ENSG00000204681.9ENST00000472823hsa-miR-6891-5p29603254296032618mer-1a2960325429603273144-23.9
CAediting_468389chr6_31355314_-ENSG00000204681.9ENST00000377016hsa-miR-6891-5p29603254296032618mer-1a2960325429603273144-23.9
CAediting_468389chr6_31355314_-ENSG00000204681.9ENST00000377012hsa-miR-6891-5p29603254296032618mer-1a2960325429603273144-23.9
CAediting_468389chr6_31355314_-ENSG00000204681.9ENST00000491829hsa-miR-6891-5p29603254296032618mer-1a2960325429603273144-23.9
CAediting_468389chr6_31355314_-ENSG00000204681.9ENST00000377034hsa-miR-6891-5p29603254296032618mer-1a2960325429603273144-23.9
CAediting_1524209chrX_134546392_-ENSG00000204681.9ENST00000489385hsa-miR-503-5p29629109296291157mer-1a2962910929629130145-23.9

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1351755chr19_40282625_-ENSG00000204681.9ENST00000472823hsa-miR-64129602745296027517mer-m82960274429602767146-12.81
CAediting_468389chr6_31355314_-ENSG00000204681.9ENST00000472823hsa-miR-6891-5p29602563296025686mer2960256229602579147-26.52
CAediting_1351755chr19_40282625_-ENSG00000204681.9ENST00000377016hsa-miR-64129602745296027517mer-m82960274429602767146-12.81
CAediting_468389chr6_31355314_-ENSG00000204681.9ENST00000377016hsa-miR-6891-5p29602563296025686mer2960256229602579147-26.52
CAediting_1351755chr19_40282625_-ENSG00000204681.9ENST00000377012hsa-miR-64129602745296027517mer-m82960274429602767146-12.81
CAediting_468389chr6_31355314_-ENSG00000204681.9ENST00000377012hsa-miR-6891-5p29602563296025686mer2960256229602579147-26.52
CAediting_1351755chr19_40282625_-ENSG00000204681.9ENST00000491829hsa-miR-64129602745296027517mer-m82960274429602767146-12.81
CAediting_468389chr6_31355314_-ENSG00000204681.9ENST00000491829hsa-miR-6891-5p29602563296025686mer2960256229602579147-26.52
CAediting_1351755chr19_40282625_-ENSG00000204681.9ENST00000377034hsa-miR-64129602745296027517mer-m82960274429602767146-12.81
CAediting_468389chr6_31355314_-ENSG00000204681.9ENST00000377034hsa-miR-6891-5p29602563296025686mer2960256229602579147-26.52

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for GABBR1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for GABBR1

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
LGGCAediting_467108chr6_29591029_-....0.01962142213865390.241644129540412
LGGCAediting_467118chr6_29591165_-..0.03064495824702760.2726203249681830.001004168075341660.404644813937153
LGGCAediting_467125chr6_29591254_-....0.008398240153343170.207715459012505

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Relation with cancer stages for GABBR1

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for GABBR1

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for GABBR1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
GABBR1Q9UBS5DB00181BaclofenGamma-aminobutyric acid type B receptor subunit 1 SmallMoleculeDrugapproved
GABBR1Q9UBS5DB02530gamma-Aminobutyric acidGamma-aminobutyric acid type B receptor subunit 1 SmallMoleculeDrugapproved|investigational
GABBR1Q9UBS5DB01956TaurineGamma-aminobutyric acid type B receptor subunit 1 SmallMoleculeDrugapproved|nutraceutical

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RelatedDiseases for GABBR1

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
GABBR1C0001973Alcoholic Intoxication, Chronic5CTD_human;PSYGENET
GABBR1C0004352Autistic Disorder2CTD_human
GABBR1C0036341Schizophrenia2PSYGENET
GABBR1C0001956Alcohol Use Disorder1CTD_human
GABBR1C0009171Cocaine Abuse1CTD_human
GABBR1C0085762Alcohol abuse1CTD_human
GABBR1C0236736Cocaine-Related Disorders1CTD_human
GABBR1C0600427Cocaine Dependence1CTD_human
GABBR1C0751217Hyperkinesia, Generalized1CTD_human
GABBR1C3887506Hyperkinesia1CTD_human