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Editing gene: SFTA3 (CAeditome ID:253970)

Gene summary for SFTA3

Gene summary

Gene information	Gene symbol	SFTA3
	Gene ID	253970
	Gene name	surfactant associated 3
	Synonyms	NANCI\|SFTPH\|SP-H\|SPH
	Cytomap	14q13.3
	Type of gene	ncRNA
	Description	NKX2.1 associated non-coding intergenic RNANkx2.1-associated noncoding intergenic RNAputative protein SFTA3surfactant-associated protein 3surfactant-associated protein H
	Modification date	20210518
	UniProtAcc	.
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
SFTA3	GO:0005615	Surfactant-associated protein 3	24743970
SFTA3	GO:0005615	Surfactant-associated protein 3	29955092
SFTA3	GO:0005737	Surfactant-associated protein 3	24743970

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RNA A-to-I events for SFTA3

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000229415.8

RNA A-to-I editing events in Cancer.

CAediting_986563(36474335, -), CAediting_986564(36476430, -), CAediting_986565(36479203, -), CAediting_986566(36479208, -), CAediting_986567(36479213, -), CAediting_986568(36479239, -), CAediting_986569(36479249, -), CAediting_986570(36479274, -), CAediting_986571(36479285, -), CAediting_986572(36479286, -), CAediting_986573(36479287, -), CAediting_986574(36479289, -), CAediting_986575(36479303, -), CAediting_986576(36479306, -), CAediting_986577(36479323, -), CAediting_986578(36479328, -), CAediting_986579(36479329, -), CAediting_986580(36479353, -), CAediting_986581(36479376, -), CAediting_986582(36479377, -), CAediting_986583(36479382, -), CAediting_986584(36479383, -), CAediting_986585(36479391, -), CAediting_986586(36479401, -), CAediting_986587(36484434, -), CAediting_986588(36484444, -), CAediting_986589(36484445, -), CAediting_986590(36484471, -), CAediting_986591(36484472, -), CAediting_986592(36484477, -), CAediting_986593(36484485, -), CAediting_986594(36484492, -), CAediting_986595(36484507, -), CAediting_986596(36484522, -), CAediting_986597(36484524, -), CAediting_986598(36484527, -), CAediting_986599(36484533, -), CAediting_986600(36484542, -), CAediting_986601(36484568, -), CAediting_986602(36484578, -), CAediting_986603(36484590, -), CAediting_986604(36484607, -), CAediting_986605(36484608, -), CAediting_986606(36484614, -), CAediting_986607(36484627, -), CAediting_986608(36484628, -), CAediting_986609(36484633, -), CAediting_986610(36484643, -), CAediting_986611(36484652, -), CAediting_986612(36484676, -), CAediting_986613(36484682, -), CAediting_986614(36486714, -), CAediting_986615(36486717, -), CAediting_986616(36486722, -), CAediting_986617(36486763, -), CAediting_986618(36486789, -), CAediting_986619(36486800, -), CAediting_986620(36486804, -), CAediting_986621(36486820, -), CAediting_986622(36486824, -), CAediting_986623(36486825, -), CAediting_986624(36486828, -), CAediting_986625(36486838, -), CAediting_986626(36486845, -), CAediting_986627(36486848, -), CAediting_986628(36486852, -), CAediting_986629(36486857, -), CAediting_986630(36486865, -), CAediting_986631(36486875, -), CAediting_986632(36486876, -), CAediting_986633(36486880, -), CAediting_986634(36486892, -), CAediting_986635(36486897, -), CAediting_986636(36486898, -), CAediting_986637(36487177, -), CAediting_986638(36487178, -), CAediting_986639(36487205, -), CAediting_986640(36487217, -), CAediting_986641(36487256, -), CAediting_986642(36487259, -), CAediting_986643(36487319, -), CAediting_986644(36487321, -), CAediting_986645(36487331, -), CAediting_986646(36487334, -), CAediting_986647(36487335, -), CAediting_986648(36487343, -), CAediting_986649(36487360, -), CAediting_986650(36487361, -), CAediting_986651(36487380, -), CAediting_986652(36487381, -), CAediting_986653(36487386, -), CAediting_986654(36487391, -), CAediting_986655(36487405, -), CAediting_986656(36487421, -), CAediting_986657(36487438, -), CAediting_986658(36490241, -), CAediting_986659(36490322, -), CAediting_986660(36490327, -), CAediting_986661(36490330, -), CAediting_986662(36490345, -), CAediting_986663(36490362, -), CAediting_986664(36490490, -), CAediting_986665(36490515, -), CAediting_986666(36490552, -), CAediting_986667(36490553, -), CAediting_986668(36490609, -), CAediting_986669(36490610, -), CAediting_986670(36490611, -), CAediting_986671(36490618, -), CAediting_986672(36490628, -), CAediting_986673(36490633, -), CAediting_986674(36490642, -),

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RNA editing positional annotations for SFTA3 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_986563	chr14_36474335_-	ncRNA_intronic
CAediting_986564	chr14_36476430_-	ncRNA_intronic
CAediting_986565	chr14_36479203_-	ncRNA_intronic
CAediting_986566	chr14_36479208_-	ncRNA_intronic
CAediting_986567	chr14_36479213_-	ncRNA_intronic
CAediting_986568	chr14_36479239_-	ncRNA_intronic
CAediting_986569	chr14_36479249_-	ncRNA_intronic
CAediting_986570	chr14_36479274_-	ncRNA_intronic
CAediting_986571	chr14_36479285_-	ncRNA_intronic
CAediting_986572	chr14_36479286_-	ncRNA_intronic
CAediting_986573	chr14_36479287_-	ncRNA_intronic
CAediting_986574	chr14_36479289_-	ncRNA_intronic
CAediting_986575	chr14_36479303_-	ncRNA_intronic
CAediting_986576	chr14_36479306_-	ncRNA_intronic
CAediting_986577	chr14_36479323_-	ncRNA_intronic
CAediting_986578	chr14_36479328_-	ncRNA_intronic
CAediting_986579	chr14_36479329_-	ncRNA_intronic
CAediting_986580	chr14_36479353_-	ncRNA_intronic
CAediting_986581	chr14_36479376_-	ncRNA_intronic
CAediting_986582	chr14_36479377_-	ncRNA_intronic
CAediting_986583	chr14_36479382_-	ncRNA_intronic
CAediting_986584	chr14_36479383_-	ncRNA_intronic
CAediting_986585	chr14_36479391_-	ncRNA_intronic
CAediting_986586	chr14_36479401_-	ncRNA_intronic
CAediting_986587	chr14_36484434_-	ncRNA_intronic
CAediting_986588	chr14_36484444_-	ncRNA_intronic
CAediting_986589	chr14_36484445_-	ncRNA_intronic
CAediting_986590	chr14_36484471_-	ncRNA_intronic
CAediting_986591	chr14_36484472_-	ncRNA_intronic
CAediting_986592	chr14_36484477_-	ncRNA_intronic
CAediting_986593	chr14_36484485_-	ncRNA_intronic
CAediting_986594	chr14_36484492_-	ncRNA_intronic
CAediting_986595	chr14_36484507_-	ncRNA_intronic
CAediting_986596	chr14_36484522_-	ncRNA_intronic
CAediting_986597	chr14_36484524_-	ncRNA_intronic
CAediting_986598	chr14_36484527_-	ncRNA_intronic
CAediting_986599	chr14_36484533_-	ncRNA_intronic
CAediting_986600	chr14_36484542_-	ncRNA_intronic
CAediting_986601	chr14_36484568_-	ncRNA_intronic
CAediting_986602	chr14_36484578_-	ncRNA_intronic
CAediting_986603	chr14_36484590_-	ncRNA_intronic
CAediting_986604	chr14_36484607_-	ncRNA_intronic
CAediting_986605	chr14_36484608_-	ncRNA_intronic
CAediting_986606	chr14_36484614_-	ncRNA_intronic
CAediting_986607	chr14_36484627_-	ncRNA_intronic
CAediting_986608	chr14_36484628_-	ncRNA_intronic
CAediting_986609	chr14_36484633_-	ncRNA_intronic
CAediting_986610	chr14_36484643_-	ncRNA_intronic
CAediting_986611	chr14_36484652_-	ncRNA_intronic
CAediting_986612	chr14_36484676_-	ncRNA_intronic
CAediting_986613	chr14_36484682_-	ncRNA_intronic
CAediting_986614	chr14_36486714_-	ncRNA_intronic
CAediting_986615	chr14_36486717_-	ncRNA_intronic
CAediting_986616	chr14_36486722_-	ncRNA_intronic
CAediting_986617	chr14_36486763_-	ncRNA_intronic
CAediting_986618	chr14_36486789_-	ncRNA_intronic
CAediting_986619	chr14_36486800_-	ncRNA_intronic
CAediting_986620	chr14_36486804_-	ncRNA_intronic
CAediting_986621	chr14_36486820_-	ncRNA_intronic
CAediting_986622	chr14_36486824_-	ncRNA_intronic
CAediting_986623	chr14_36486825_-	ncRNA_intronic
CAediting_986624	chr14_36486828_-	ncRNA_intronic
CAediting_986625	chr14_36486838_-	ncRNA_intronic
CAediting_986626	chr14_36486845_-	ncRNA_intronic
CAediting_986627	chr14_36486848_-	ncRNA_intronic
CAediting_986628	chr14_36486852_-	ncRNA_intronic
CAediting_986629	chr14_36486857_-	ncRNA_intronic
CAediting_986630	chr14_36486865_-	ncRNA_intronic
CAediting_986631	chr14_36486875_-	ncRNA_intronic
CAediting_986632	chr14_36486876_-	ncRNA_intronic
CAediting_986633	chr14_36486880_-	ncRNA_intronic
CAediting_986634	chr14_36486892_-	ncRNA_intronic
CAediting_986635	chr14_36486897_-	ncRNA_intronic
CAediting_986636	chr14_36486898_-	ncRNA_intronic
CAediting_986637	chr14_36487177_-	ncRNA_intronic
CAediting_986638	chr14_36487178_-	ncRNA_intronic
CAediting_986639	chr14_36487205_-	ncRNA_intronic
CAediting_986640	chr14_36487217_-	ncRNA_intronic
CAediting_986641	chr14_36487256_-	ncRNA_intronic
CAediting_986642	chr14_36487259_-	ncRNA_intronic
CAediting_986643	chr14_36487319_-	ncRNA_intronic
CAediting_986644	chr14_36487321_-	ncRNA_intronic
CAediting_986645	chr14_36487331_-	ncRNA_intronic
CAediting_986646	chr14_36487334_-	ncRNA_intronic
CAediting_986647	chr14_36487335_-	ncRNA_intronic
CAediting_986648	chr14_36487343_-	ncRNA_intronic
CAediting_986649	chr14_36487360_-	ncRNA_intronic
CAediting_986650	chr14_36487361_-	ncRNA_intronic
CAediting_986651	chr14_36487380_-	ncRNA_intronic
CAediting_986652	chr14_36487381_-	ncRNA_intronic
CAediting_986653	chr14_36487386_-	ncRNA_intronic
CAediting_986654	chr14_36487391_-	ncRNA_intronic
CAediting_986655	chr14_36487405_-	ncRNA_intronic
CAediting_986656	chr14_36487421_-	ncRNA_intronic
CAediting_986657	chr14_36487438_-	ncRNA_intronic
CAediting_986658	chr14_36490241_-	ncRNA_intronic
CAediting_986659	chr14_36490322_-	ncRNA_intronic
CAediting_986660	chr14_36490327_-	ncRNA_intronic
CAediting_986661	chr14_36490330_-	ncRNA_intronic
CAediting_986662	chr14_36490345_-	ncRNA_intronic
CAediting_986663	chr14_36490362_-	ncRNA_intronic
CAediting_986664	chr14_36490490_-	ncRNA_intronic
CAediting_986665	chr14_36490515_-	ncRNA_intronic
CAediting_986666	chr14_36490552_-	ncRNA_intronic
CAediting_986667	chr14_36490553_-	ncRNA_intronic
CAediting_986668	chr14_36490609_-	ncRNA_intronic
CAediting_986669	chr14_36490610_-	ncRNA_intronic
CAediting_986670	chr14_36490611_-	ncRNA_intronic
CAediting_986671	chr14_36490618_-	ncRNA_intronic
CAediting_986672	chr14_36490628_-	ncRNA_intronic
CAediting_986673	chr14_36490633_-	ncRNA_intronic
CAediting_986674	chr14_36490642_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_986563	chr14_36474335_-	SINE	Alu	AluSx3
CAediting_986564	chr14_36476430_-	SINE	Alu	AluY
CAediting_986565	chr14_36479203_-	SINE	Alu	AluJb
CAediting_986566	chr14_36479208_-	SINE	Alu	AluJb
CAediting_986567	chr14_36479213_-	SINE	Alu	AluJb
CAediting_986568	chr14_36479239_-	SINE	Alu	AluJb
CAediting_986569	chr14_36479249_-	SINE	Alu	AluJb
CAediting_986570	chr14_36479274_-	SINE	Alu	AluJb
CAediting_986571	chr14_36479285_-	SINE	Alu	AluJb
CAediting_986572	chr14_36479286_-	SINE	Alu	AluJb
CAediting_986573	chr14_36479287_-	SINE	Alu	AluJb
CAediting_986574	chr14_36479289_-	SINE	Alu	AluJb
CAediting_986575	chr14_36479303_-	SINE	Alu	AluJb
CAediting_986576	chr14_36479306_-	SINE	Alu	AluJb
CAediting_986577	chr14_36479323_-	SINE	Alu	AluJb
CAediting_986578	chr14_36479328_-	SINE	Alu	AluJb
CAediting_986579	chr14_36479329_-	SINE	Alu	AluJb
CAediting_986580	chr14_36479353_-	SINE	Alu	AluJb
CAediting_986581	chr14_36479376_-	SINE	Alu	AluJb
CAediting_986582	chr14_36479377_-	SINE	Alu	AluJb
CAediting_986583	chr14_36479382_-	SINE	Alu	AluJb
CAediting_986584	chr14_36479383_-	SINE	Alu	AluJb
CAediting_986585	chr14_36479391_-	SINE	Alu	AluJb
CAediting_986586	chr14_36479401_-	SINE	Alu	AluJb
CAediting_986587	chr14_36484434_-	SINE	Alu	AluSz
CAediting_986588	chr14_36484444_-	SINE	Alu	AluSz
CAediting_986589	chr14_36484445_-	SINE	Alu	AluSz
CAediting_986590	chr14_36484471_-	SINE	Alu	AluSz
CAediting_986591	chr14_36484472_-	SINE	Alu	AluSz
CAediting_986592	chr14_36484477_-	SINE	Alu	AluSz
CAediting_986593	chr14_36484485_-	SINE	Alu	AluSz
CAediting_986594	chr14_36484492_-	SINE	Alu	AluSz
CAediting_986595	chr14_36484507_-	SINE	Alu	AluSz
CAediting_986596	chr14_36484522_-	SINE	Alu	AluSz
CAediting_986597	chr14_36484524_-	SINE	Alu	AluSz
CAediting_986598	chr14_36484527_-	SINE	Alu	AluSz
CAediting_986599	chr14_36484533_-	SINE	Alu	AluSz
CAediting_986600	chr14_36484542_-	SINE	Alu	AluSz
CAediting_986601	chr14_36484568_-	SINE	Alu	AluSz
CAediting_986602	chr14_36484578_-	SINE	Alu	AluSz
CAediting_986603	chr14_36484590_-	SINE	Alu	AluSz
CAediting_986604	chr14_36484607_-	SINE	Alu	AluSz
CAediting_986605	chr14_36484608_-	SINE	Alu	AluSz
CAediting_986606	chr14_36484614_-	SINE	Alu	AluSz
CAediting_986607	chr14_36484627_-	SINE	Alu	AluSz
CAediting_986608	chr14_36484628_-	SINE	Alu	AluSz
CAediting_986609	chr14_36484633_-	SINE	Alu	AluSz
CAediting_986610	chr14_36484643_-	SINE	Alu	AluSz
CAediting_986611	chr14_36484652_-	SINE	Alu	AluSz
CAediting_986612	chr14_36484676_-	SINE	Alu	AluSz
CAediting_986613	chr14_36484682_-	SINE	Alu	AluSz
CAediting_986614	chr14_36486714_-	SINE	Alu	AluJb
CAediting_986615	chr14_36486717_-	SINE	Alu	AluJb
CAediting_986616	chr14_36486722_-	SINE	Alu	AluJb
CAediting_986617	chr14_36486763_-	SINE	Alu	AluJb
CAediting_986618	chr14_36486789_-	SINE	Alu	AluJb
CAediting_986619	chr14_36486800_-	SINE	Alu	AluJb
CAediting_986620	chr14_36486804_-	SINE	Alu	AluJb
CAediting_986621	chr14_36486820_-	SINE	Alu	AluJb
CAediting_986622	chr14_36486824_-	SINE	Alu	AluJb
CAediting_986623	chr14_36486825_-	SINE	Alu	AluJb
CAediting_986624	chr14_36486828_-	SINE	Alu	AluJb
CAediting_986625	chr14_36486838_-	SINE	Alu	AluJb
CAediting_986626	chr14_36486845_-	SINE	Alu	AluJb
CAediting_986627	chr14_36486848_-	SINE	Alu	AluJb
CAediting_986628	chr14_36486852_-	SINE	Alu	AluJb
CAediting_986629	chr14_36486857_-	SINE	Alu	AluJb
CAediting_986630	chr14_36486865_-	SINE	Alu	AluJb
CAediting_986631	chr14_36486875_-	SINE	Alu	AluJb
CAediting_986632	chr14_36486876_-	SINE	Alu	AluJb
CAediting_986633	chr14_36486880_-	SINE	Alu	AluJb
CAediting_986634	chr14_36486892_-	SINE	Alu	AluJb
CAediting_986635	chr14_36486897_-	SINE	Alu	AluJb
CAediting_986636	chr14_36486898_-	SINE	Alu	AluJb
CAediting_986637	chr14_36487177_-	SINE	Alu	AluSx3
CAediting_986638	chr14_36487178_-	SINE	Alu	AluSx3
CAediting_986639	chr14_36487205_-	SINE	Alu	AluSx3
CAediting_986640	chr14_36487217_-	SINE	Alu	AluSx3
CAediting_986641	chr14_36487256_-	SINE	Alu	AluSx3
CAediting_986642	chr14_36487259_-	SINE	Alu	AluSx3
CAediting_986643	chr14_36487319_-	SINE	Alu	AluSx3
CAediting_986644	chr14_36487321_-	SINE	Alu	AluSx3
CAediting_986645	chr14_36487331_-	SINE	Alu	AluSx3
CAediting_986646	chr14_36487334_-	SINE	Alu	AluSx3
CAediting_986647	chr14_36487335_-	SINE	Alu	AluSx3
CAediting_986648	chr14_36487343_-	SINE	Alu	AluSx3
CAediting_986649	chr14_36487360_-	SINE	Alu	AluSx3
CAediting_986650	chr14_36487361_-	SINE	Alu	AluSx3
CAediting_986651	chr14_36487380_-	SINE	Alu	AluSx3
CAediting_986652	chr14_36487381_-	SINE	Alu	AluSx3
CAediting_986653	chr14_36487386_-	SINE	Alu	AluSx3
CAediting_986654	chr14_36487391_-	SINE	Alu	AluSx3
CAediting_986655	chr14_36487405_-	SINE	Alu	AluSx3
CAediting_986656	chr14_36487421_-	SINE	Alu	AluSx3
CAediting_986657	chr14_36487438_-	SINE	Alu	AluSx3
CAediting_986658	chr14_36490241_-	SINE	Alu	AluJb
CAediting_986659	chr14_36490322_-	SINE	Alu	AluJb
CAediting_986660	chr14_36490327_-	SINE	Alu	AluJb
CAediting_986661	chr14_36490330_-	SINE	Alu	AluJb
CAediting_986662	chr14_36490345_-	SINE	Alu	AluJb
CAediting_986663	chr14_36490362_-	SINE	Alu	AluJb
CAediting_986664	chr14_36490490_-	SINE	Alu	AluSq2
CAediting_986665	chr14_36490515_-	SINE	Alu	AluSq2
CAediting_986666	chr14_36490552_-	SINE	Alu	AluSq2
CAediting_986667	chr14_36490553_-	SINE	Alu	AluSq2
CAediting_986668	chr14_36490609_-	SINE	Alu	AluSq2
CAediting_986669	chr14_36490610_-	SINE	Alu	AluSq2
CAediting_986670	chr14_36490611_-	SINE	Alu	AluSq2
CAediting_986671	chr14_36490618_-	SINE	Alu	AluSq2
CAediting_986672	chr14_36490628_-	SINE	Alu	AluSq2
CAediting_986673	chr14_36490633_-	SINE	Alu	AluSq2
CAediting_986674	chr14_36490642_-	SINE	Alu	AluSq2

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RNA A-to-I editing events in the alternative splicing sites for SFTA3

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000229415.8.SFTA3.

Correlation between RNA A-to-I editing and PSI for ENSG00000229415.8.SFTA3.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SFTA3

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

LUAD.CAediting_986633.ENSG00000229415.SFTA3.png
Soverview

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Protein coding region RNA A-to-I editings for SFTA3

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for SFTA3

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_688080	chr9_63819626_+	ENSG00000229415.8	ENST00000518529.5	hsa-miR-4477b	36513657	36513663	7mer-m8	36513656	36513677	152	-17.51
CAediting_1054808	chr15_66496985_-	ENSG00000229415.8	ENST00000518529.5	hsa-miR-4512	36513564	36513569	6mer	36513563	36513586	142	-31.33
CAediting_396018	chr5_1062918_-	ENSG00000229415.8	ENST00000518529.5	hsa-miR-4635	36513656	36513662	7mer-m8	36513655	36513675	146	-19.44
CAediting_442554	chr5_154685830_+	ENSG00000229415.8	ENST00000518529.5	hsa-miR-1303	36513306	36513312	7mer-m8	36513305	36513328	145	-15.59
CAediting_580943	chr7_100356700_+	ENSG00000229415.8	ENST00000518529.5	hsa-miR-6840-3p	36513698	36513704	7mer-m8	36513697	36513719	153	-26.17
CAediting_524911	chr7_5495852_-	ENSG00000229415.8	ENST00000518529.5	hsa-miR-589-3p	36513721	36513728	8mer-1a	36513721	36513743	147	-17.66
CAediting_442554	chr5_154685830_+	ENSG00000229415.8	ENST00000518987.4	hsa-miR-1303	36513306	36513312	7mer-m8	36513305	36513328	145	-15.59
CAediting_442554	chr5_154685830_+	ENSG00000229415.8	ENST00000521114.4	hsa-miR-1303	36513306	36513312	7mer-m8	36513305	36513328	145	-15.59
CAediting_580943	chr7_100356700_+	ENSG00000229415.8	ENST00000518446.1	hsa-miR-6840-3p	36513698	36513704	7mer-m8	36513697	36513719	153	-26.17
CAediting_524911	chr7_5495852_-	ENSG00000229415.8	ENST00000518446.1	hsa-miR-589-3p	36513721	36513728	8mer-1a	36513721	36513743	147	-17.66
CAediting_468389	chr6_31355314_-	ENSG00000229415.8	ENST00000524122.4	hsa-miR-6891-5p	36477755	36477761	7mer-m8	36477754	36477771	146	-18.96
CAediting_468389	chr6_31355314_-	ENSG00000229415.8	ENST00000521114.4	hsa-miR-6891-5p	36477755	36477761	7mer-m8	36477754	36477771	146	-18.96
CAediting_468389	chr6_31355314_-	ENSG00000229415.8	ENST00000518446.1	hsa-miR-6891-5p	36477755	36477761	7mer-m8	36477754	36477771	146	-18.96

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1524209	chrX_134546392_-	ENSG00000229415.8	ENST00000518529.5	hsa-miR-503-5p	36513592	36513597	6mer	36513591	36513615	147	-28.89
CAediting_580943	chr7_100356700_+	ENSG00000229415.8	ENST00000518529.5	hsa-miR-6840-3p	36513360	36513366	7mer-m8	36513359	36513380	140	-17.71
CAediting_580943	chr7_100356700_+	ENSG00000229415.8	ENST00000518987.4	hsa-miR-6840-3p	36513360	36513366	7mer-m8	36513359	36513380	140	-17.71
CAediting_748296	chr10_51299626_+	ENSG00000229415.8	ENST00000521380.1	hsa-miR-605-3p	36477313	36477319	7mer-m8	36477312	36477333	150	-17.04
CAediting_580943	chr7_100356700_+	ENSG00000229415.8	ENST00000521114.4	hsa-miR-6840-3p	36513360	36513366	7mer-m8	36513359	36513380	140	-17.71

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for SFTA3

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for SFTA3

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
THCA	CAediting_986565	chr14_36479203_-	0.00277577700048257	0.370788852954264	.	.	.	.
THCA	CAediting_986594	chr14_36484492_-	0.00650317479055036	0.284860160430267	.	.	.	.
LUAD	CAediting_986598	chr14_36484527_-	0.013459050425976	0.229874104475152	.	.	.	.
THCA	CAediting_986598	chr14_36484527_-	0.0225815063497426	0.173823685570933	.	.	.	.
LUAD	CAediting_986618	chr14_36486789_-	0.00271331337247603	0.312480360963554	.	.	.	.
THCA	CAediting_986632	chr14_36486876_-	0.00104238855769495	0.416224318271135	.	.	.	.
THCA	CAediting_986644	chr14_36487321_-	0.00262201395062202	0.384756273873583	.	.	.	.

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Relation with cancer stages for SFTA3

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
LUAD	pathologic_stage	CAediting_986633	chr14_36486880_-	0.00316167898859349	0.332187871735431
THCA	pathologic_stage	CAediting_986565	chr14_36479203_-	0.0348303684075412	0.270731899517992

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Relation with survival for SFTA3

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for SFTA3

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for SFTA3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene