Home

Download

Statistics

Examples

Help

Contact

Editing gene: RNASEH1 (CAeditome ID:246243)

Gene summary for RNASEH1

Gene summary

Gene information	Gene symbol	RNASEH1
	Gene ID	246243
	Gene name	ribonuclease H1
	Synonyms	H1RNA\|PEOB2\|RNH1
	Cytomap	2p25.3
	Type of gene	protein-coding
	Description	ribonuclease H1ribonuclease H type II
	Modification date	20210518
	UniProtAcc	O60930
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
RNASEH1	GO:0004523	Ribonuclease H1	21700224

Top

RNA A-to-I events for RNASEH1

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000171865.8

RNA A-to-I editing events in Cancer.

CAediting_154321(3544867, -), CAediting_154322(3544877, -), CAediting_154323(3544884, -), CAediting_154324(3544896, -), CAediting_154325(3544913, -), CAediting_154326(3544923, -), CAediting_154327(3544935, -), CAediting_154328(3544952, -), CAediting_154329(3544953, -), CAediting_154330(3544954, -), CAediting_154331(3544978, -), CAediting_154332(3545002, -), CAediting_154333(3545007, -), CAediting_154334(3545015, -), CAediting_154335(3545017, -), CAediting_154336(3545026, -), CAediting_154337(3545031, -), CAediting_154338(3545039, -), CAediting_154339(3545042, -), CAediting_154340(3545047, -), CAediting_154341(3545048, -), CAediting_154342(3545056, -), CAediting_154343(3545064, -), CAediting_154344(3547001, -), CAediting_154345(3547015, -), CAediting_154346(3547195, -), CAediting_154347(3553611, -), CAediting_154348(3555968, -),

Top

RNA editing positional annotations for RNASEH1 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_154321	chr2_3544867_-	UTR3
CAediting_154322	chr2_3544877_-	UTR3
CAediting_154323	chr2_3544884_-	UTR3
CAediting_154324	chr2_3544896_-	UTR3
CAediting_154325	chr2_3544913_-	UTR3
CAediting_154326	chr2_3544923_-	UTR3
CAediting_154327	chr2_3544935_-	UTR3
CAediting_154328	chr2_3544952_-	UTR3
CAediting_154329	chr2_3544953_-	UTR3
CAediting_154330	chr2_3544954_-	UTR3
CAediting_154331	chr2_3544978_-	UTR3
CAediting_154332	chr2_3545002_-	UTR3
CAediting_154333	chr2_3545007_-	UTR3
CAediting_154334	chr2_3545015_-	UTR3
CAediting_154335	chr2_3545017_-	UTR3
CAediting_154336	chr2_3545026_-	UTR3
CAediting_154337	chr2_3545031_-	UTR3
CAediting_154338	chr2_3545039_-	UTR3
CAediting_154339	chr2_3545042_-	UTR3
CAediting_154340	chr2_3545047_-	UTR3
CAediting_154341	chr2_3545048_-	UTR3
CAediting_154342	chr2_3545056_-	UTR3
CAediting_154343	chr2_3545064_-	UTR3
CAediting_154344	chr2_3547001_-	intronic
CAediting_154345	chr2_3547015_-	intronic
CAediting_154346	chr2_3547195_-	intronic
CAediting_154347	chr2_3553611_-	intronic
CAediting_154348	chr2_3555968_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_154321	chr2_3544867_-	SINE	Alu	AluSz6
CAediting_154322	chr2_3544877_-	SINE	Alu	AluSz6
CAediting_154323	chr2_3544884_-	SINE	Alu	AluSz6
CAediting_154324	chr2_3544896_-	SINE	Alu	AluSz6
CAediting_154325	chr2_3544913_-	SINE	Alu	AluSz6
CAediting_154326	chr2_3544923_-	SINE	Alu	AluSz6
CAediting_154327	chr2_3544935_-	SINE	Alu	AluSz6
CAediting_154328	chr2_3544952_-	SINE	Alu	AluSz6
CAediting_154329	chr2_3544953_-	SINE	Alu	AluSz6
CAediting_154330	chr2_3544954_-	SINE	Alu	AluSz6
CAediting_154331	chr2_3544978_-	SINE	Alu	AluSz6
CAediting_154332	chr2_3545002_-	SINE	Alu	AluSz6
CAediting_154333	chr2_3545007_-	SINE	Alu	AluSz6
CAediting_154334	chr2_3545015_-	SINE	Alu	AluSz6
CAediting_154335	chr2_3545017_-	SINE	Alu	AluSz6
CAediting_154336	chr2_3545026_-	SINE	Alu	AluSz6
CAediting_154337	chr2_3545031_-	SINE	Alu	AluSz6
CAediting_154338	chr2_3545039_-	SINE	Alu	AluSz6
CAediting_154339	chr2_3545042_-	SINE	Alu	AluSz6
CAediting_154340	chr2_3545047_-	SINE	Alu	AluSz6
CAediting_154341	chr2_3545048_-	SINE	Alu	AluSz6
CAediting_154342	chr2_3545056_-	SINE	Alu	AluSz6
CAediting_154343	chr2_3545064_-	SINE	Alu	AluSz6
CAediting_154344	chr2_3547001_-	SINE	Alu	AluSz6
CAediting_154345	chr2_3547015_-	SINE	Alu	AluSz6
CAediting_154346	chr2_3547195_-	SINE	Alu	AluJb
CAediting_154347	chr2_3553611_-	SINE	Alu	AluSg7
CAediting_154348	chr2_3555968_-	SINE	Alu	AluSz

Top

RNA A-to-I editing events in the alternative splicing sites for RNASEH1

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000171865.8.RNASEH1.

Correlation between RNA A-to-I editing and PSI for ENSG00000171865.8.RNASEH1.

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for RNASEH1

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Top

Protein coding region RNA A-to-I editings for RNASEH1

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

Top

The effects of the RNA editing to the miRNA binding sites for RNASEH1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_154329	chr2_3544953_-	ENSG00000171865.8	ENST00000436842	hsa-miR-325	3544952	3544959	8mer-1a	3544952	3544974	141.00	-15.16
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-518a-3p	3545035	3545041	7mer-m8	3545034	3545055	145.00	-14.83
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-518a-3p	3545035	3545041	7mer-m8	3545034	3545055	145.00	-14.83
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-518b	3545035	3545041	7mer-m8	3545034	3545056	151.00	-22.33
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-518c-3p	3545035	3545041	7mer-m8	3545034	3545057	151.00	-21.53
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-518d-3p	3545035	3545041	7mer-m8	3545034	3545055	146.00	-19.01
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-518e-3p	3545036	3545042	7mer-m8	3545035	3545056	150.00	-17.10
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-518f-3p	3545035	3545041	7mer-m8	3545034	3545055	150.00	-16.83
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-526a-3p	3545035	3545041	7mer-m8	3545034	3545056	151.00	-18.92
CAediting_154340	chr2_3545047_-	ENSG00000171865.8	ENST00000436842	hsa-miR-3117-3p	3545042	3545048	7mer-m8	3545041	3545061	154.00	-16.21
CAediting_154340	chr2_3545047_-	ENSG00000171865.8	ENST00000436842	hsa-miR-4759	3545042	3545049	8mer-1a	3545042	3545064	147.00	-14.70
CAediting_154342	chr2_3545056_-	ENSG00000171865.8	ENST00000436842	hsa-miR-7706	3545052	3545057	6mer	3545051	3545078	140.00	-32.77
CAediting_154324	chr2_3544896_-	ENSG00000171865.8	ENST00000436842	hsa-miR-3943	3544892	3544898	7mer-m8	3544891	3544911	146.00	-22.28
CAediting_154330	chr2_3544954_-	ENSG00000171865.8	ENST00000436842	hsa-miR-205-3p	3544950	3544956	7mer-m8	3544949	3544969	162.00	-19.17
CAediting_154330	chr2_3544954_-	ENSG00000171865.8	ENST00000436842	hsa-miR-222-5p	3544952	3544959	8mer-1a	3544952	3544975	146.00	-12.72
CAediting_154330	chr2_3544954_-	ENSG00000171865.8	ENST00000436842	hsa-miR-30a-3p	3544951	3544957	7mer-m8	3544950	3544975	147.00	-10.56
CAediting_154330	chr2_3544954_-	ENSG00000171865.8	ENST00000436842	hsa-miR-30d-3p	3544951	3544957	7mer-m8	3544950	3544975	147.00	-11.33
CAediting_154330	chr2_3544954_-	ENSG00000171865.8	ENST00000436842	hsa-miR-30e-3p	3544951	3544957	7mer-m8	3544950	3544975	147.00	-10.94
CAediting_154330	chr2_3544954_-	ENSG00000171865.8	ENST00000436842	hsa-miR-936	3544953	3544960	8mer-1a	3544953	3544974	158.00	-25.74
CAediting_154331	chr2_3544978_-	ENSG00000171865.8	ENST00000436842	hsa-miR-3190-5p	3544978	3544984	7mer-m8	3544977	3544996	151.00	-19.64
CAediting_154334	chr2_3545015_-	ENSG00000171865.8	ENST00000436842	hsa-miR-6747-3p	3545015	3545020	6mer	3545014	3545034	140.00	-24.49
CAediting_154339	chr2_3545042_-	ENSG00000171865.8	ENST00000436842	hsa-miR-5006-5p	3545039	3545045	7mer-m8	3545038	3545060	153.00	-24.37

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_154340	chr2_3545047_-	ENSG00000171865.8	ENST00000436842	hsa-miR-10399-5p	3545046	3545052	7mer-m8	3545045	3545066	148	-11.84
CAediting_154341	chr2_3545048_-	ENSG00000171865.8	ENST00000436842	hsa-miR-10399-5p	3545046	3545052	7mer-m8	3545045	3545066	148	-11.84
CAediting_154326	chr2_3544923_-	ENSG00000171865.8	ENST00000436842	hsa-miR-1227-3p	3544922	3544928	7mer-m8	3544921	3544940	145	-21.91
CAediting_154334	chr2_3545015_-	ENSG00000171865.8	ENST00000436842	hsa-miR-1245a	3545010	3545016	7mer-m8	3545009	3545029	153	-18.22
CAediting_154327	chr2_3544935_-	ENSG00000171865.8	ENST00000436842	hsa-miR-1261	3544935	3544941	7mer-m8	3544934	3544951	145	-10.68
CAediting_154337	chr2_3545031_-	ENSG00000171865.8	ENST00000436842	hsa-miR-150-5p	3545030	3545036	7mer-m8	3545029	3545050	140	-15.8
CAediting_154324	chr2_3544896_-	ENSG00000171865.8	ENST00000436842	hsa-miR-150-5p	3544895	3544901	7mer-m8	3544894	3544917	142	-15.65
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-302a-3p	3545036	3545042	7mer-m8	3545035	3545057	141	-11.48
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-302b-3p	3545036	3545042	7mer-m8	3545035	3545057	141	-12.78
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-302c-3p	3545036	3545042	7mer-m8	3545035	3545055	145	-12.19
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-302d-3p	3545036	3545042	7mer-m8	3545035	3545057	144	-13.3
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-302e	3545036	3545042	7mer-m8	3545035	3545051	141	-8.91
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-372-3p	3545036	3545042	7mer-m8	3545035	3545055	149	-13.47
CAediting_154343	chr2_3545064_-	ENSG00000171865.8	ENST00000436842	hsa-miR-4252	3545059	3545065	7mer-m8	3545058	3545077	154	-21.53
CAediting_154321	chr2_3544867_-	ENSG00000171865.8	ENST00000436842	hsa-miR-4485-5p	3544862	3544868	7mer-m8	3544861	3544876	140	-14.86
CAediting_154331	chr2_3544978_-	ENSG00000171865.8	ENST00000436842	hsa-miR-4781-3p	3544975	3544981	7mer-m8	3544974	3544992	144	-13.79
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-512-3p	3545037	3545042	6mer	3545036	3545057	144	-17.41
CAediting_154339	chr2_3545042_-	ENSG00000171865.8	ENST00000436842	hsa-miR-512-3p	3545037	3545042	6mer	3545036	3545057	144	-17.41
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-512-3p	3545037	3545042	6mer	3545036	3545057	144	-17.41
CAediting_154339	chr2_3545042_-	ENSG00000171865.8	ENST00000436842	hsa-miR-512-3p	3545037	3545042	6mer	3545036	3545057	144	-17.41
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-519d-3p	3545035	3545041	7mer-m8	3545034	3545054	146	-14.9
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-520a-3p	3545036	3545042	7mer-m8	3545035	3545057	141	-11.26
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-520b-3p	3545036	3545042	7mer-m8	3545035	3545056	146	-17.73
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-520c-3p	3545036	3545042	7mer-m8	3545035	3545057	151	-17.73
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-520d-3p	3545036	3545042	7mer-m8	3545035	3545056	140	-11.85
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-520e-3p	3545036	3545042	7mer-m8	3545035	3545055	140	-12.27
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-520h	3545034	3545040	7mer-m8	3545033	3545055	155	-17.05
CAediting_154338	chr2_3545039_-	ENSG00000171865.8	ENST00000436842	hsa-miR-526b-3p	3545035	3545041	7mer-m8	3545034	3545056	151	-17.41
CAediting_154323	chr2_3544884_-	ENSG00000171865.8	ENST00000436842	hsa-miR-550b-2-5p	3544883	3544890	8mer-1a	3544883	3544904	147	-17.35
CAediting_154323	chr2_3544884_-	ENSG00000171865.8	ENST00000436842	hsa-miR-550b-2-5p	3544883	3544890	8mer-1a	3544883	3544904	147	-17.35
CAediting_154328	chr2_3544952_-	ENSG00000171865.8	ENST00000436842	hsa-miR-590-3p	3544948	3544955	8mer-1a	3544948	3544967	151	-8.87
CAediting_154329	chr2_3544953_-	ENSG00000171865.8	ENST00000436842	hsa-miR-590-3p	3544948	3544955	8mer-1a	3544948	3544967	151	-8.87
CAediting_154330	chr2_3544954_-	ENSG00000171865.8	ENST00000436842	hsa-miR-590-3p	3544948	3544955	8mer-1a	3544948	3544967	151	-8.87
CAediting_154343	chr2_3545064_-	ENSG00000171865.8	ENST00000436842	hsa-miR-6529-3p	3545063	3545069	7mer-m8	3545062	3545092	147	-17.32
CAediting_154321	chr2_3544867_-	ENSG00000171865.8	ENST00000436842	hsa-miR-661	3544864	3544870	7mer-m8	3544863	3544885	149	-20.56
CAediting_154321	chr2_3544867_-	ENSG00000171865.8	ENST00000436842	hsa-miR-6742-3p	3544865	3544871	7mer-m8	3544864	3544883	145	-14.92
CAediting_154327	chr2_3544935_-	ENSG00000171865.8	ENST00000436842	hsa-miR-6765-3p	3544931	3544937	7mer-m8	3544930	3544950	144	-18.02
CAediting_154337	chr2_3545031_-	ENSG00000171865.8	ENST00000436842	hsa-miR-6778-3p	3545028	3545034	7mer-m8	3545027	3545047	143	-13.97
CAediting_154324	chr2_3544896_-	ENSG00000171865.8	ENST00000436842	hsa-miR-6778-3p	3544893	3544899	7mer-m8	3544892	3544912	140	-14.56
CAediting_154342	chr2_3545056_-	ENSG00000171865.8	ENST00000436842	hsa-miR-6807-5p	3545056	3545062	7mer-m8	3545055	3545076	147	-21.32
CAediting_154336	chr2_3545026_-	ENSG00000171865.8	ENST00000436842	hsa-miR-6878-3p	3545025	3545032	8mer-1a	3545025	3545045	142	-17.1
CAediting_154337	chr2_3545031_-	ENSG00000171865.8	ENST00000436842	hsa-miR-6878-3p	3545025	3545032	8mer-1a	3545025	3545045	142	-17.1
CAediting_154343	chr2_3545064_-	ENSG00000171865.8	ENST00000436842	hsa-miR-6889-3p	3545063	3545069	7mer-m8	3545062	3545081	145	-16.08
CAediting_154322	chr2_3544877_-	ENSG00000171865.8	ENST00000436842	hsa-miR-8062	3544875	3544881	7mer-m8	3544874	3544896	144	-10.32
CAediting_154334	chr2_3545015_-	ENSG00000171865.8	ENST00000436842	hsa-miR-8079	3545010	3545016	7mer-m8	3545009	3545027	151	-17.19
CAediting_154343	chr2_3545064_-	ENSG00000171865.8	ENST00000436842	hsa-miR-892a	3545062	3545067	6mer	3545061	3545081	143	-23.47

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_980496	chr14_31014685_-	ENSG00000171865.8	ENST00000436842	hsa-miR-624-3p	3544962	3544968	7mer-m8	3544961	3544981	156	-14.45
CAediting_77128	chr1_85133844_+	ENSG00000171865.8	ENST00000436842	hsa-miR-4423-3p	3545343	3545349	7mer-m8	3545342	3545362	142	-15.88
CAediting_1524209	chrX_134546392_-	ENSG00000171865.8	ENST00000436842	hsa-miR-503-5p	3556864	3556870	7mer-1a	3556864	3556887	156	-28.47
CAediting_1524209	chrX_134546392_-	ENSG00000171865.8	ENST00000436842	hsa-miR-503-5p	3545732	3545737	6mer	3545731	3545753	149	-27.12
CAediting_1524209	chrX_134546392_-	ENSG00000171865.8	ENST00000454734	hsa-miR-503-5p	3556864	3556870	7mer-1a	3556864	3556887	156	-28.47

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1368054	chr19_46709310_-	ENSG00000171865.8	ENST00000436842	hsa-miR-320e	3544984	3544990	7mer-m8	3544983	3545000	151	-12.57

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for RNASEH1

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000436842.4	nonsense_mediated_decay

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_154321	ENST00000436842.4	chr2_3544867_-	-781.62	-782.42	-800.20
CAediting_154322	ENST00000436842.4	chr2_3544877_-	-784.92	-782.42	-800.20
CAediting_154323	ENST00000436842.4	chr2_3544884_-	-782.12	-782.42	-800.20
CAediting_154324	ENST00000436842.4	chr2_3544896_-	-782.52	-782.42	-800.20
CAediting_154325	ENST00000436842.4	chr2_3544913_-	-782.52	-782.42	-800.20
CAediting_154326	ENST00000436842.4	chr2_3544923_-	-781.72	-782.42	-800.20
CAediting_154327	ENST00000436842.4	chr2_3544935_-	-782.42	-782.42	-800.20
CAediting_154328	ENST00000436842.4	chr2_3544952_-	-782.72	-782.42	-800.20
CAediting_154329	ENST00000436842.4	chr2_3544953_-	-782.42	-782.42	-800.20
CAediting_154330	ENST00000436842.4	chr2_3544954_-	-782.42	-782.42	-800.20
CAediting_154331	ENST00000436842.4	chr2_3544978_-	-782.42	-782.42	-800.20
CAediting_154332	ENST00000436842.4	chr2_3545002_-	-781.62	-782.42	-800.20
CAediting_154333	ENST00000436842.4	chr2_3545007_-	-782.42	-782.42	-800.20
CAediting_154334	ENST00000436842.4	chr2_3545015_-	-781.02	-782.42	-800.20
CAediting_154335	ENST00000436842.4	chr2_3545017_-	-781.62	-782.42	-800.20
CAediting_154336	ENST00000436842.4	chr2_3545026_-	-782.12	-782.42	-800.20
CAediting_154337	ENST00000436842.4	chr2_3545031_-	-782.82	-782.42	-800.20
CAediting_154338	ENST00000436842.4	chr2_3545039_-	-785.72	-782.42	-800.20
CAediting_154339	ENST00000436842.4	chr2_3545042_-	-785.22	-782.42	-800.20
CAediting_154340	ENST00000436842.4	chr2_3545047_-	-781.52	-782.42	-800.20
CAediting_154341	ENST00000436842.4	chr2_3545048_-	-781.52	-782.42	-800.20
CAediting_154342	ENST00000436842.4	chr2_3545056_-	-782.02	-782.42	-800.20
CAediting_154343	ENST00000436842.4	chr2_3545064_-	-781.72	-782.42	-800.20

Top

Relation with ADAR for RNASEH1

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
OV	CAediting_154335	chr2_3545017_-	0.0362184702390422	0.16319985160281	.	.	.	.
LGG	CAediting_154341	chr2_3545048_-	0.0455543673019059	0.284101270445822	.	.	.	.
BRCA	CAediting_154341	chr2_3545048_-	0.0496487204464053	0.121637597616244	.	.	.	.
SKCM	CAediting_154341	chr2_3545048_-	0.0406215081637086	0.201135747655045	.	.	.	.

Top

Relation with cancer stages for RNASEH1

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

Top

Relation with survival for RNASEH1

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
ESCA	CAediting_154341	chr2_3545048_-	0.0307944578077718	0.0130353	20827.3

Top

RelatedDrugs for RNASEH1

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

RelatedDiseases for RNASEH1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
RNASEH1	C4225312	PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS, AUTOSOMAL RECESSIVE 2	1	CTD_human;GENOMICS_ENGLAND;UNIPROT
RNASEH1	C4511138	Adult-onset chronic progressive external ophthalmoplegia with mitochondrial myopathy	1	ORPHANET

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene