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Editing gene: HEBP2 (CAeditome ID:23593)

Gene summary for HEBP2

Gene summary

Gene information	Gene symbol	HEBP2
	Gene ID	23593
	Gene name	heme binding protein 2
	Synonyms	C6ORF34B\|C6orf34\|PP23\|SOUL
	Cytomap	6q24.1
	Type of gene	protein-coding
	Description	heme-binding protein 2placental protein 23
	Modification date	20210518
	UniProtAcc	Q9Y5Z4
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
HEBP2	GO:0005737	Heme-binding protein 2	17098234
HEBP2	GO:0005739	Heme-binding protein 2	17098234

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RNA A-to-I events for HEBP2

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000051620.9

RNA A-to-I editing events in Cancer.

CAediting_506113(138406798, +), CAediting_506114(138406812, +), CAediting_506115(138406824, +), CAediting_506116(138406848, +), CAediting_506117(138406849, +), CAediting_506118(138406856, +), CAediting_506119(138406933, +), CAediting_506120(138406946, +), CAediting_506121(138406956, +), CAediting_506122(138406959, +), CAediting_506123(138406976, +), CAediting_506124(138406983, +), CAediting_506125(138406988, +), CAediting_506126(138409048, +), CAediting_506127(138409050, +), CAediting_506128(138409080, +), CAediting_506129(138409088, +), CAediting_506130(138409096, +), CAediting_506131(138409126, +), CAediting_506132(138409127, +), CAediting_506133(138409139, +), CAediting_506134(138409144, +), CAediting_506135(138409199, +), CAediting_506136(138409205, +), CAediting_506137(138409225, +), CAediting_506138(138409250, +), CAediting_506139(138409251, +), CAediting_506140(138409254, +), CAediting_506141(138409263, +), CAediting_506142(138409268, +), CAediting_506143(138409277, +), CAediting_506144(138409278, +), CAediting_506145(138409290, +), CAediting_506146(138409293, +), CAediting_506147(138409296, +), CAediting_506148(138410526, +), CAediting_506149(138410533, +), CAediting_506150(138410535, +), CAediting_506151(138410575, +), CAediting_506152(138410600, +), CAediting_506153(138410612, +), CAediting_506154(138410652, +), CAediting_506155(138410666, +), CAediting_506156(138410669, +), CAediting_506157(138410671, +), CAediting_506158(138410695, +), CAediting_506159(138410720, +), CAediting_506160(138410725, +), CAediting_506161(138410748, +), CAediting_506162(138411675, +), CAediting_506163(138411694, +), CAediting_506164(138411700, +), CAediting_506165(138411702, +), CAediting_506166(138411703, +), CAediting_506167(138411724, +), CAediting_506168(138411725, +), CAediting_506169(138411729, +), CAediting_506170(138411738, +), CAediting_506171(138411743, +), CAediting_506172(138411748, +), CAediting_506173(138411751, +), CAediting_506174(138411762, +), CAediting_506175(138411776, +), CAediting_506176(138411779, +), CAediting_506177(138411807, +), CAediting_506178(138411836, +), CAediting_506179(138411840, +), CAediting_506180(138411853, +), CAediting_506181(138411871, +), CAediting_506182(138411876, +), CAediting_506183(138411917, +), CAediting_506184(138411926, +), CAediting_506185(138412457, +), CAediting_506186(138412463, +), CAediting_506187(138412471, +), CAediting_506188(138412473, +), CAediting_506189(138412474, +), CAediting_506190(138412475, +), CAediting_506191(138412497, +), CAediting_506192(138412540, +), CAediting_506193(138412547, +), CAediting_506194(138412558, +), CAediting_506195(138412571, +), CAediting_506196(138412579, +), CAediting_506197(138412580, +), CAediting_506198(138412583, +), CAediting_506199(138412584, +), CAediting_506200(138412593, +), CAediting_506201(138412595, +), CAediting_506202(138412619, +), CAediting_506203(138412651, +), CAediting_506204(138412663, +), CAediting_506205(138412688, +), CAediting_506206(138412689, +), CAediting_506207(138412693, +), CAediting_506208(138412701, +), CAediting_506209(138412715, +), CAediting_506210(138412716, +), CAediting_506211(138412728, +), CAediting_506212(138412730, +),

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RNA editing positional annotations for HEBP2 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_506113	chr6_138406798_+	intronic
CAediting_506114	chr6_138406812_+	intronic
CAediting_506115	chr6_138406824_+	intronic
CAediting_506116	chr6_138406848_+	intronic
CAediting_506117	chr6_138406849_+	intronic
CAediting_506118	chr6_138406856_+	intronic
CAediting_506119	chr6_138406933_+	intronic
CAediting_506120	chr6_138406946_+	intronic
CAediting_506121	chr6_138406956_+	intronic
CAediting_506122	chr6_138406959_+	intronic
CAediting_506123	chr6_138406976_+	intronic
CAediting_506124	chr6_138406983_+	intronic
CAediting_506125	chr6_138406988_+	intronic
CAediting_506126	chr6_138409048_+	intronic
CAediting_506127	chr6_138409050_+	intronic
CAediting_506128	chr6_138409080_+	intronic
CAediting_506129	chr6_138409088_+	intronic
CAediting_506130	chr6_138409096_+	intronic
CAediting_506131	chr6_138409126_+	intronic
CAediting_506132	chr6_138409127_+	intronic
CAediting_506133	chr6_138409139_+	intronic
CAediting_506134	chr6_138409144_+	intronic
CAediting_506135	chr6_138409199_+	intronic
CAediting_506136	chr6_138409205_+	intronic
CAediting_506137	chr6_138409225_+	intronic
CAediting_506138	chr6_138409250_+	intronic
CAediting_506139	chr6_138409251_+	intronic
CAediting_506140	chr6_138409254_+	intronic
CAediting_506141	chr6_138409263_+	intronic
CAediting_506142	chr6_138409268_+	intronic
CAediting_506143	chr6_138409277_+	intronic
CAediting_506144	chr6_138409278_+	intronic
CAediting_506145	chr6_138409290_+	intronic
CAediting_506146	chr6_138409293_+	intronic
CAediting_506147	chr6_138409296_+	intronic
CAediting_506148	chr6_138410526_+	intronic
CAediting_506149	chr6_138410533_+	intronic
CAediting_506150	chr6_138410535_+	intronic
CAediting_506151	chr6_138410575_+	intronic
CAediting_506152	chr6_138410600_+	intronic
CAediting_506153	chr6_138410612_+	intronic
CAediting_506154	chr6_138410652_+	intronic
CAediting_506155	chr6_138410666_+	intronic
CAediting_506156	chr6_138410669_+	intronic
CAediting_506157	chr6_138410671_+	intronic
CAediting_506158	chr6_138410695_+	intronic
CAediting_506159	chr6_138410720_+	intronic
CAediting_506160	chr6_138410725_+	intronic
CAediting_506161	chr6_138410748_+	intronic
CAediting_506162	chr6_138411675_+	intronic
CAediting_506163	chr6_138411694_+	intronic
CAediting_506164	chr6_138411700_+	intronic
CAediting_506165	chr6_138411702_+	intronic
CAediting_506166	chr6_138411703_+	intronic
CAediting_506167	chr6_138411724_+	intronic
CAediting_506168	chr6_138411725_+	intronic
CAediting_506169	chr6_138411729_+	intronic
CAediting_506170	chr6_138411738_+	intronic
CAediting_506171	chr6_138411743_+	intronic
CAediting_506172	chr6_138411748_+	intronic
CAediting_506173	chr6_138411751_+	intronic
CAediting_506174	chr6_138411762_+	intronic
CAediting_506175	chr6_138411776_+	intronic
CAediting_506176	chr6_138411779_+	intronic
CAediting_506177	chr6_138411807_+	intronic
CAediting_506178	chr6_138411836_+	intronic
CAediting_506179	chr6_138411840_+	intronic
CAediting_506180	chr6_138411853_+	intronic
CAediting_506181	chr6_138411871_+	intronic
CAediting_506182	chr6_138411876_+	intronic
CAediting_506183	chr6_138411917_+	intronic
CAediting_506184	chr6_138411926_+	intronic
CAediting_506185	chr6_138412457_+	intronic
CAediting_506186	chr6_138412463_+	intronic
CAediting_506187	chr6_138412471_+	intronic
CAediting_506188	chr6_138412473_+	intronic
CAediting_506189	chr6_138412474_+	intronic
CAediting_506190	chr6_138412475_+	intronic
CAediting_506191	chr6_138412497_+	intronic
CAediting_506192	chr6_138412540_+	intronic
CAediting_506193	chr6_138412547_+	intronic
CAediting_506194	chr6_138412558_+	intronic
CAediting_506195	chr6_138412571_+	intronic
CAediting_506196	chr6_138412579_+	intronic
CAediting_506197	chr6_138412580_+	intronic
CAediting_506198	chr6_138412583_+	intronic
CAediting_506199	chr6_138412584_+	intronic
CAediting_506200	chr6_138412593_+	intronic
CAediting_506201	chr6_138412595_+	intronic
CAediting_506202	chr6_138412619_+	intronic
CAediting_506203	chr6_138412651_+	intronic
CAediting_506204	chr6_138412663_+	intronic
CAediting_506205	chr6_138412688_+	intronic
CAediting_506206	chr6_138412689_+	intronic
CAediting_506207	chr6_138412693_+	intronic
CAediting_506208	chr6_138412701_+	intronic
CAediting_506209	chr6_138412715_+	intronic
CAediting_506210	chr6_138412716_+	intronic
CAediting_506211	chr6_138412728_+	intronic
CAediting_506212	chr6_138412730_+	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_506113	chr6_138406798_+	SINE	Alu	AluJb
CAediting_506114	chr6_138406812_+	SINE	Alu	AluJb
CAediting_506115	chr6_138406824_+	SINE	Alu	AluJb
CAediting_506116	chr6_138406848_+	SINE	Alu	AluJb
CAediting_506117	chr6_138406849_+	SINE	Alu	AluJb
CAediting_506118	chr6_138406856_+	SINE	Alu	AluJb
CAediting_506119	chr6_138406933_+	SINE	Alu	AluJb
CAediting_506120	chr6_138406946_+	SINE	Alu	AluJb
CAediting_506121	chr6_138406956_+	SINE	Alu	AluJb
CAediting_506122	chr6_138406959_+	SINE	Alu	AluJb
CAediting_506123	chr6_138406976_+	SINE	Alu	AluJb
CAediting_506124	chr6_138406983_+	SINE	Alu	AluJb
CAediting_506125	chr6_138406988_+	SINE	Alu	AluJb
CAediting_506126	chr6_138409048_+	SINE	Alu	AluJo
CAediting_506127	chr6_138409050_+	SINE	Alu	AluJo
CAediting_506128	chr6_138409080_+	SINE	Alu	AluJo
CAediting_506129	chr6_138409088_+	SINE	Alu	AluJo
CAediting_506130	chr6_138409096_+	SINE	Alu	AluJo
CAediting_506131	chr6_138409126_+	SINE	Alu	AluJo
CAediting_506132	chr6_138409127_+	SINE	Alu	AluJo
CAediting_506133	chr6_138409139_+	SINE	Alu	AluJo
CAediting_506134	chr6_138409144_+	SINE	Alu	AluJo
CAediting_506135	chr6_138409199_+	SINE	Alu	AluJo
CAediting_506136	chr6_138409205_+	SINE	Alu	AluJo
CAediting_506137	chr6_138409225_+	SINE	Alu	AluJo
CAediting_506138	chr6_138409250_+	SINE	Alu	AluJo
CAediting_506139	chr6_138409251_+	SINE	Alu	AluJo
CAediting_506140	chr6_138409254_+	SINE	Alu	AluJo
CAediting_506141	chr6_138409263_+	SINE	Alu	AluJo
CAediting_506142	chr6_138409268_+	SINE	Alu	AluJo
CAediting_506143	chr6_138409277_+	SINE	Alu	AluJo
CAediting_506144	chr6_138409278_+	SINE	Alu	AluJo
CAediting_506145	chr6_138409290_+	SINE	Alu	AluJo
CAediting_506146	chr6_138409293_+	SINE	Alu	AluJo
CAediting_506147	chr6_138409296_+	SINE	Alu	AluJo
CAediting_506148	chr6_138410526_+	SINE	Alu	AluSq2
CAediting_506149	chr6_138410533_+	SINE	Alu	AluSq2
CAediting_506150	chr6_138410535_+	SINE	Alu	AluSq2
CAediting_506151	chr6_138410575_+	SINE	Alu	AluSq2
CAediting_506152	chr6_138410600_+	SINE	Alu	AluSq2
CAediting_506153	chr6_138410612_+	SINE	Alu	AluSq2
CAediting_506154	chr6_138410652_+	SINE	Alu	AluSq2
CAediting_506155	chr6_138410666_+	SINE	Alu	AluSq2
CAediting_506156	chr6_138410669_+	SINE	Alu	AluSq2
CAediting_506157	chr6_138410671_+	SINE	Alu	AluSq2
CAediting_506158	chr6_138410695_+	SINE	Alu	AluSq2
CAediting_506159	chr6_138410720_+	SINE	Alu	AluSq2
CAediting_506160	chr6_138410725_+	SINE	Alu	AluSq2
CAediting_506161	chr6_138410748_+	SINE	Alu	AluSq2
CAediting_506163	chr6_138411694_+	SINE	Alu	AluJb
CAediting_506164	chr6_138411700_+	SINE	Alu	AluJb
CAediting_506165	chr6_138411702_+	SINE	Alu	AluJb
CAediting_506166	chr6_138411703_+	SINE	Alu	AluJb
CAediting_506167	chr6_138411724_+	SINE	Alu	AluJb
CAediting_506168	chr6_138411725_+	SINE	Alu	AluJb
CAediting_506169	chr6_138411729_+	SINE	Alu	AluJb
CAediting_506170	chr6_138411738_+	SINE	Alu	AluJb
CAediting_506171	chr6_138411743_+	SINE	Alu	AluJb
CAediting_506172	chr6_138411748_+	SINE	Alu	AluJb
CAediting_506173	chr6_138411751_+	SINE	Alu	AluJb
CAediting_506174	chr6_138411762_+	SINE	Alu	AluJb
CAediting_506175	chr6_138411776_+	SINE	Alu	AluJb
CAediting_506176	chr6_138411779_+	SINE	Alu	AluJb
CAediting_506177	chr6_138411807_+	SINE	Alu	AluJb
CAediting_506178	chr6_138411836_+	SINE	Alu	AluJb
CAediting_506179	chr6_138411840_+	SINE	Alu	AluJb
CAediting_506180	chr6_138411853_+	SINE	Alu	AluJb
CAediting_506181	chr6_138411871_+	SINE	Alu	AluJb
CAediting_506182	chr6_138411876_+	SINE	Alu	AluJb
CAediting_506183	chr6_138411917_+	SINE	Alu	AluJb
CAediting_506184	chr6_138411926_+	SINE	Alu	AluJb
CAediting_506185	chr6_138412457_+	SINE	Alu	AluSx1
CAediting_506186	chr6_138412463_+	SINE	Alu	AluSx1
CAediting_506187	chr6_138412471_+	SINE	Alu	AluSx1
CAediting_506188	chr6_138412473_+	SINE	Alu	AluSx1
CAediting_506189	chr6_138412474_+	SINE	Alu	AluSx1
CAediting_506190	chr6_138412475_+	SINE	Alu	AluSx1
CAediting_506191	chr6_138412497_+	SINE	Alu	AluSx1
CAediting_506192	chr6_138412540_+	SINE	Alu	AluSx1
CAediting_506193	chr6_138412547_+	SINE	Alu	AluSx1
CAediting_506194	chr6_138412558_+	SINE	Alu	AluSx1
CAediting_506195	chr6_138412571_+	SINE	Alu	AluSx1
CAediting_506196	chr6_138412579_+	SINE	Alu	AluSx1
CAediting_506197	chr6_138412580_+	SINE	Alu	AluSx1
CAediting_506198	chr6_138412583_+	SINE	Alu	AluSx1
CAediting_506199	chr6_138412584_+	SINE	Alu	AluSx1
CAediting_506200	chr6_138412593_+	SINE	Alu	AluSx1
CAediting_506201	chr6_138412595_+	SINE	Alu	AluSx1
CAediting_506202	chr6_138412619_+	SINE	Alu	AluSx1
CAediting_506203	chr6_138412651_+	SINE	Alu	AluSx1
CAediting_506204	chr6_138412663_+	SINE	Alu	AluSx1
CAediting_506205	chr6_138412688_+	SINE	Alu	AluSx1
CAediting_506206	chr6_138412689_+	SINE	Alu	AluSx1
CAediting_506207	chr6_138412693_+	SINE	Alu	AluSx1
CAediting_506208	chr6_138412701_+	SINE	Alu	AluSx1
CAediting_506209	chr6_138412715_+	SINE	Alu	AluSx1
CAediting_506210	chr6_138412716_+	SINE	Alu	AluSx1
CAediting_506211	chr6_138412728_+	SINE	Alu	AluSx1
CAediting_506212	chr6_138412730_+	SINE	Alu	AluSx1

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RNA A-to-I editing events in the alternative splicing sites for HEBP2

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000051620.9.HEBP2.

Correlation between RNA A-to-I editing and PSI for ENSG00000051620.9.HEBP2.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for HEBP2

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for HEBP2

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for HEBP2

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_393	chr1_1167164_+	ENSG00000051620.9	ENST00000607197	hsa-miR-200b-3p	138415290	138415296	7mer-m8	138415276	138415297	149	-12.45
CAediting_688081	chr9_63819627_+	ENSG00000051620.9	ENST00000607197	hsa-miR-4477b	138415899	138415905	7mer-m8	138415885	138415906	140	-8.57
CAediting_1054808	chr15_66496985_-	ENSG00000051620.9	ENST00000607197	hsa-miR-4512	138415332	138415338	7mer-m8	138415319	138415339	146	-24.51
CAediting_1054808	chr15_66496985_-	ENSG00000051620.9	ENST00000607197	hsa-miR-4512	138413911	138413917	7mer-m8	138413896	138413918	145	-18.66
CAediting_1229414	chr17_67471546_+	ENSG00000051620.9	ENST00000607197	hsa-miR-548aa	138413299	138413305	7mer-m8	138413284	138413306	163	-17.24
CAediting_117844	chr1_162342605_+	ENSG00000051620.9	ENST00000607197	hsa-miR-556-3p	138419866	138419872	7mer-m8	138419854	138419873	142	-10.56
CAediting_77128	chr1_85133844_+	ENSG00000051620.9	ENST00000607197	hsa-miR-4423-3p	138419107	138419113	7mer-m8	138419092	138419114	153	-18.75
CAediting_524911	chr7_5495852_-	ENSG00000051620.9	ENST00000607197	hsa-miR-589-3p	138415109	138415115	7mer-m8	138415093	138415116	154	-15.49
CAediting_1054808	chr15_66496985_-	ENSG00000051620.9	ENST00000453452	hsa-miR-4512	138412211	138412218	8mer-1a	138412195	138412218	155	-21.71
CAediting_77128	chr1_85133844_+	ENSG00000051620.9	ENST00000453452	hsa-miR-4423-3p	138412899	138412906	8mer-1a	138412885	138412906	157	-13.86
CAediting_468389	chr6_31355314_-	ENSG00000051620.9	ENST00000607197	hsa-miR-6891-5p	138417103	138417109	7mer-m8	138417095	138417113	156	-22.43
CAediting_468389	chr6_31355314_-	ENSG00000051620.9	ENST00000607197	hsa-miR-6891-5p	138417106	138417112	7mer-m8	138417095	138417113	156	-22.43
CAediting_468389	chr6_31355314_-	ENSG00000051620.9	ENST00000607197	hsa-miR-6891-5p	138417313	138417318	6mer	138417301	138417319	144	-23.17
CAediting_468389	chr6_31355314_-	ENSG00000051620.9	ENST00000607197	hsa-miR-6891-5p	138421279	138421284	6mer	138421267	138421285	145	-27.85
CAediting_468389	chr6_31355314_-	ENSG00000051620.9	ENST00000607197	hsa-miR-6891-5p	138421888	138421894	7mer-m8	138421877	138421895	152	-19.93

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1160181	chr17_7017644_-	ENSG00000051620.9	ENST00000607197	hsa-miR-195-3p	138417343	138417349	7mer-m8	138417329	138417350	153	-8.5
CAediting_1160181	chr17_7017644_-	ENSG00000051620.9	ENST00000607197	hsa-miR-195-3p	138419869	138419875	7mer-m8	138419855	138419876	153	-11.09
CAediting_86358	chr1_109598906_+	ENSG00000051620.9	ENST00000607197	hsa-miR-197-5p	138417017	138417023	7mer-m8	138417002	138417024	149	-19.72
CAediting_86358	chr1_109598906_+	ENSG00000051620.9	ENST00000607197	hsa-miR-197-5p	138421601	138421607	7mer-m8	138421583	138421608	145	-15.94
CAediting_393	chr1_1167164_+	ENSG00000051620.9	ENST00000607197	hsa-miR-200b-3p	138417357	138417363	7mer-m8	138417341	138417364	155	-15.33
CAediting_1306324	chr19_13836464_-	ENSG00000051620.9	ENST00000607197	hsa-miR-27a-3p	138417507	138417513	7mer-m8	138417494	138417514	140	-12.45
CAediting_1306324	chr19_13836464_-	ENSG00000051620.9	ENST00000607197	hsa-miR-27a-3p	138418036	138418043	8mer-1a	138418026	138418043	155	-14.92
CAediting_1306324	chr19_13836464_-	ENSG00000051620.9	ENST00000607197	hsa-miR-27a-3p	138419228	138419234	7mer-m8	138419215	138419235	151	-16.52
CAediting_1306324	chr19_13836464_-	ENSG00000051620.9	ENST00000607197	hsa-miR-27a-3p	138413892	138413899	8mer-1a	138413879	138413899	150	-17.47
CAediting_1306324	chr19_13836464_-	ENSG00000051620.9	ENST00000607197	hsa-miR-27a-3p	138421360	138421366	7mer-m8	138421348	138421367	149	-15.83
CAediting_604450	chr7_133034877_-	ENSG00000051620.9	ENST00000607197	hsa-miR-3654	138415387	138415393	7mer-m8	138415376	138415394	149	-15.66
CAediting_604450	chr7_133034877_-	ENSG00000051620.9	ENST00000607197	hsa-miR-3654	138417544	138417550	7mer-m8	138417532	138417551	142	-12.7
CAediting_688081	chr9_63819627_+	ENSG00000051620.9	ENST00000607197	hsa-miR-4477b	138413866	138413872	7mer-m8	138413852	138413873	140	-9.9
CAediting_396018	chr5_1062918_-	ENSG00000051620.9	ENST00000607197	hsa-miR-4635	138414547	138414554	8mer-1a	138414534	138414554	140	-11.27
CAediting_396018	chr5_1062918_-	ENSG00000051620.9	ENST00000607197	hsa-miR-4635	138420460	138420467	8mer-1a	138420447	138420467	143	-10.61
CAediting_1229413	chr17_67471544_+	ENSG00000051620.9	ENST00000607197	hsa-miR-548aa	138417474	138417480	7mer-m8	138417457	138417481	148	-6.21
CAediting_1229414	chr17_67471546_+	ENSG00000051620.9	ENST00000607197	hsa-miR-548aa	138417474	138417480	7mer-m8	138417457	138417481	148	-6.21
CAediting_1229415	chr17_67471547_+	ENSG00000051620.9	ENST00000607197	hsa-miR-548aa	138417474	138417480	7mer-m8	138417457	138417481	148	-6.21
CAediting_524911	chr7_5495852_-	ENSG00000051620.9	ENST00000607197	hsa-miR-589-3p	138421011	138421017	7mer-m8	138420995	138421018	145	-13.73
CAediting_980496	chr14_31014685_-	ENSG00000051620.9	ENST00000607197	hsa-miR-624-3p	138418852	138418858	7mer-m8	138418838	138418859	149	-16.27
CAediting_468389	chr6_31355314_-	ENSG00000051620.9	ENST00000607197	hsa-miR-6891-5p	138420920	138420926	7mer-m8	138420909	138420927	140	-16.56

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for HEBP2

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for HEBP2

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
PRAD	CAediting_506169	chr6_138411729_+	.	.	0.000891575614985219	0.245565393610714	.	.
BRCA	CAediting_506170	chr6_138411738_+	0.0003336323111921	0.447806094134337	.	.	.	.
PRAD	CAediting_506170	chr6_138411738_+	.	.	.	.	0.0367137311828712	0.184856349693101
BLCA	CAediting_506182	chr6_138411876_+	.	.	0.0487195406543497	0.274727613898611	.	.
LUSC	CAediting_506189	chr6_138412474_+	0.0113512553813664	0.307547582188776	.	.	.	.
LUSC	CAediting_506190	chr6_138412475_+	0.0257411948134512	0.27240106472063	.	.	.	.
BRCA	CAediting_506197	chr6_138412580_+	0.013143631078648	0.297190041574336	.	.	.	.
PRAD	CAediting_506197	chr6_138412580_+	0.00340971395275171	0.222735954974307	.	.	.	.

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Relation with cancer stages for HEBP2

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BRCA	pathologic_stage	CAediting_506182	chr6_138411876_+	0.000754913314140539	0.328312506314323

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Relation with survival for HEBP2

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
OV	CAediting_506189	chr6_138412474_+	0.0408241195379849	0.0299938	11.8528

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RelatedDrugs for HEBP2

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for HEBP2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
HEBP2	C0023903	Liver neoplasms	1	CTD_human
HEBP2	C0345904	Malignant neoplasm of liver	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene