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Editing gene: CBX5 (CAeditome ID:23468)

Gene summary for CBX5

Gene summary

Gene information	Gene symbol	CBX5
	Gene ID	23468
	Gene name	chromobox 5
	Synonyms	HEL25\|HP1\|HP1A
	Cytomap	12q13.13
	Type of gene	protein-coding
	Description	chromobox protein homolog 5HP1 alpha homologHP1-ALPHAHP1Hs alphaantigen p25chromobox homolog 5 (HP1 alpha homolog, Drosophila)epididymis luminal protein 25heterochromatin protein 1 homolog alphaheterochromatin protein 1-alpha
	Modification date	20210518
	UniProtAcc	P45973
	Context	- 26791953(Regulatory dissection of the CBX5 and hnRNPA1 bi-directional promoter in human breast cancer cells reveals novel transcript variants differentially associated with HP1a down-regulation in metastatic cells)

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
CBX5	GO:0035064	Chromobox protein homolog 5	19783980
CBX5	GO:0035064	Chromobox protein homolog 5	21029866
CBX5	GO:0043021	Chromobox protein homolog 5	19617346
CBX5	GO:0044877	Chromobox protein homolog 5	19617346
CBX5	GO:0045892	Chromobox protein homolog 5	9636147
CBX5	GO:0005634	Chromobox protein homolog 5	19617346
CBX5	GO:0005634	Chromobox protein homolog 5	19783980
CBX5	GO:0005634	Chromobox protein homolog 5	9636146
CBX5	GO:0005654	Chromobox protein homolog 5	0000052
CBX5	GO:0005730	Chromobox protein homolog 5	9636146
CBX5	GO:0032991	Chromobox protein homolog 5	19617346
CBX5	GO:1990904	Chromobox protein homolog 5	19617346

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RNA A-to-I events for CBX5

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000094916.12

RNA A-to-I editing events in Cancer.

CAediting_894358(54231069, -), CAediting_894359(54231075, -), CAediting_894360(54233656, -), CAediting_894361(54233661, -), CAediting_894362(54233674, -), CAediting_894363(54233686, -), CAediting_894364(54233687, -), CAediting_894365(54233696, -), CAediting_894366(54233705, -), CAediting_894367(54233713, -), CAediting_894368(54233757, -), CAediting_894369(54233761, -), CAediting_894370(54233763, -), CAediting_894371(54233803, -), CAediting_894372(54233814, -), CAediting_894373(54233816, -), CAediting_894374(54233829, -), CAediting_894375(54233830, -), CAediting_894376(54233854, -), CAediting_894377(54233855, -), CAediting_894378(54233856, -), CAediting_894379(54233870, -), CAediting_894380(54233938, -), CAediting_894381(54234014, -), CAediting_894382(54234017, -), CAediting_894383(54234058, -), CAediting_894384(54234068, -), CAediting_894385(54234080, -), CAediting_894386(54234093, -), CAediting_894387(54234096, -), CAediting_894388(54234097, -), CAediting_894389(54234122, -), CAediting_894390(54234170, -), CAediting_894391(54235358, -), CAediting_894392(54235421, -), CAediting_894393(54235425, -), CAediting_894394(54235447, -), CAediting_894395(54235465, -), CAediting_894396(54235492, -), CAediting_894397(54235502, -), CAediting_894398(54235505, -), CAediting_894399(54235514, -), CAediting_894400(54235610, -), CAediting_894401(54235612, -), CAediting_894402(54237933, -), CAediting_894403(54237935, -), CAediting_894404(54237947, -), CAediting_894405(54237948, -), CAediting_894406(54237949, -), CAediting_894407(54237978, -), CAediting_894408(54238024, -), CAediting_894409(54238052, -), CAediting_894410(54238078, -), CAediting_894411(54238090, -), CAediting_894412(54238107, -), CAediting_894413(54238108, -), CAediting_894414(54238157, -), CAediting_894415(54238181, -), CAediting_894416(54238183, -), CAediting_894417(54238187, -), CAediting_894418(54240426, -), CAediting_894419(54240451, -), CAediting_894420(54240452, -), CAediting_894421(54240458, -), CAediting_894422(54240459, -), CAediting_894423(54240467, -), CAediting_894424(54240470, -), CAediting_894425(54240477, -), CAediting_894426(54240483, -), CAediting_894427(54240491, -), CAediting_894428(54240494, -), CAediting_894429(54240500, -), CAediting_894430(54240509, -), CAediting_894431(54240516, -), CAediting_894432(54240518, -), CAediting_894433(54240522, -), CAediting_894434(54245088, -), CAediting_894435(54245140, -), CAediting_894436(54245175, -), CAediting_894437(54248005, -), CAediting_894438(54249126, -), CAediting_894439(54254214, -), CAediting_894440(54261370, -), CAediting_894441(54261559, -),

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RNA editing positional annotations for CBX5 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_894358	chr12_54231069_-	UTR3
CAediting_894359	chr12_54231075_-	UTR3
CAediting_894360	chr12_54233656_-	UTR3
CAediting_894361	chr12_54233661_-	UTR3
CAediting_894362	chr12_54233674_-	UTR3
CAediting_894363	chr12_54233686_-	UTR3
CAediting_894364	chr12_54233687_-	UTR3
CAediting_894365	chr12_54233696_-	UTR3
CAediting_894366	chr12_54233705_-	UTR3
CAediting_894367	chr12_54233713_-	UTR3
CAediting_894368	chr12_54233757_-	UTR3
CAediting_894369	chr12_54233761_-	UTR3
CAediting_894370	chr12_54233763_-	UTR3
CAediting_894371	chr12_54233803_-	UTR3
CAediting_894372	chr12_54233814_-	UTR3
CAediting_894373	chr12_54233816_-	UTR3
CAediting_894374	chr12_54233829_-	UTR3
CAediting_894375	chr12_54233830_-	UTR3
CAediting_894376	chr12_54233854_-	UTR3
CAediting_894377	chr12_54233855_-	UTR3
CAediting_894378	chr12_54233856_-	UTR3
CAediting_894379	chr12_54233870_-	UTR3
CAediting_894380	chr12_54233938_-	UTR3
CAediting_894381	chr12_54234014_-	UTR3
CAediting_894382	chr12_54234017_-	UTR3
CAediting_894383	chr12_54234058_-	UTR3
CAediting_894384	chr12_54234068_-	UTR3
CAediting_894385	chr12_54234080_-	UTR3
CAediting_894386	chr12_54234093_-	UTR3
CAediting_894387	chr12_54234096_-	UTR3
CAediting_894388	chr12_54234097_-	UTR3
CAediting_894389	chr12_54234122_-	UTR3
CAediting_894390	chr12_54234170_-	UTR3
CAediting_894391	chr12_54235358_-	UTR3
CAediting_894392	chr12_54235421_-	UTR3
CAediting_894393	chr12_54235425_-	UTR3
CAediting_894394	chr12_54235447_-	UTR3
CAediting_894395	chr12_54235465_-	UTR3
CAediting_894396	chr12_54235492_-	UTR3
CAediting_894397	chr12_54235502_-	UTR3
CAediting_894398	chr12_54235505_-	UTR3
CAediting_894399	chr12_54235514_-	UTR3
CAediting_894400	chr12_54235610_-	UTR3
CAediting_894401	chr12_54235612_-	UTR3
CAediting_894402	chr12_54237933_-	UTR3
CAediting_894403	chr12_54237935_-	UTR3
CAediting_894404	chr12_54237947_-	UTR3
CAediting_894405	chr12_54237948_-	UTR3
CAediting_894406	chr12_54237949_-	UTR3
CAediting_894407	chr12_54237978_-	UTR3
CAediting_894408	chr12_54238024_-	UTR3
CAediting_894409	chr12_54238052_-	UTR3
CAediting_894410	chr12_54238078_-	UTR3
CAediting_894411	chr12_54238090_-	UTR3
CAediting_894412	chr12_54238107_-	UTR3
CAediting_894413	chr12_54238108_-	UTR3
CAediting_894414	chr12_54238157_-	UTR3
CAediting_894415	chr12_54238181_-	UTR3
CAediting_894416	chr12_54238183_-	UTR3
CAediting_894417	chr12_54238187_-	UTR3
CAediting_894418	chr12_54240426_-	UTR3
CAediting_894419	chr12_54240451_-	UTR3
CAediting_894420	chr12_54240452_-	UTR3
CAediting_894421	chr12_54240458_-	UTR3
CAediting_894422	chr12_54240459_-	UTR3
CAediting_894423	chr12_54240467_-	UTR3
CAediting_894424	chr12_54240470_-	UTR3
CAediting_894425	chr12_54240477_-	UTR3
CAediting_894426	chr12_54240483_-	UTR3
CAediting_894427	chr12_54240491_-	UTR3
CAediting_894428	chr12_54240494_-	UTR3
CAediting_894429	chr12_54240500_-	UTR3
CAediting_894430	chr12_54240509_-	UTR3
CAediting_894431	chr12_54240516_-	UTR3
CAediting_894432	chr12_54240518_-	UTR3
CAediting_894433	chr12_54240522_-	UTR3
CAediting_894434	chr12_54245088_-	ncRNA_intronic
CAediting_894435	chr12_54245140_-	ncRNA_intronic
CAediting_894436	chr12_54245175_-	ncRNA_intronic
CAediting_894437	chr12_54248005_-	ncRNA_intronic
CAediting_894438	chr12_54249126_-	ncRNA_intronic
CAediting_894439	chr12_54254214_-	intronic
CAediting_894440	chr12_54261370_-	intronic
CAediting_894441	chr12_54261559_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_894360	chr12_54233656_-	SINE	Alu	AluJo
CAediting_894361	chr12_54233661_-	SINE	Alu	AluJo
CAediting_894362	chr12_54233674_-	SINE	Alu	AluJo
CAediting_894363	chr12_54233686_-	SINE	Alu	AluJo
CAediting_894364	chr12_54233687_-	SINE	Alu	AluJo
CAediting_894365	chr12_54233696_-	SINE	Alu	AluJo
CAediting_894366	chr12_54233705_-	SINE	Alu	AluJo
CAediting_894367	chr12_54233713_-	SINE	Alu	AluJo
CAediting_894368	chr12_54233757_-	SINE	Alu	AluJo
CAediting_894369	chr12_54233761_-	SINE	Alu	AluJo
CAediting_894370	chr12_54233763_-	SINE	Alu	AluJo
CAediting_894371	chr12_54233803_-	SINE	Alu	AluJo
CAediting_894372	chr12_54233814_-	SINE	Alu	AluJo
CAediting_894373	chr12_54233816_-	SINE	Alu	AluJo
CAediting_894374	chr12_54233829_-	SINE	Alu	AluJo
CAediting_894375	chr12_54233830_-	SINE	Alu	AluJo
CAediting_894376	chr12_54233854_-	SINE	Alu	AluJo
CAediting_894377	chr12_54233855_-	SINE	Alu	AluJo
CAediting_894378	chr12_54233856_-	SINE	Alu	AluJo
CAediting_894379	chr12_54233870_-	SINE	Alu	AluJo
CAediting_894380	chr12_54233938_-	SINE	Alu	AluSg7
CAediting_894381	chr12_54234014_-	SINE	Alu	AluSg7
CAediting_894382	chr12_54234017_-	SINE	Alu	AluSg7
CAediting_894383	chr12_54234058_-	SINE	Alu	AluSg7
CAediting_894384	chr12_54234068_-	SINE	Alu	AluSg7
CAediting_894385	chr12_54234080_-	SINE	Alu	AluSg7
CAediting_894386	chr12_54234093_-	SINE	Alu	AluSg7
CAediting_894387	chr12_54234096_-	SINE	Alu	AluSg7
CAediting_894388	chr12_54234097_-	SINE	Alu	AluSg7
CAediting_894389	chr12_54234122_-	SINE	Alu	AluSg7
CAediting_894390	chr12_54234170_-	SINE	Alu	AluSg7
CAediting_894391	chr12_54235358_-	SINE	Alu	AluY
CAediting_894392	chr12_54235421_-	SINE	Alu	AluY
CAediting_894393	chr12_54235425_-	SINE	Alu	AluY
CAediting_894394	chr12_54235447_-	SINE	Alu	AluY
CAediting_894395	chr12_54235465_-	SINE	Alu	AluY
CAediting_894396	chr12_54235492_-	SINE	Alu	AluY
CAediting_894397	chr12_54235502_-	SINE	Alu	AluY
CAediting_894398	chr12_54235505_-	SINE	Alu	AluY
CAediting_894399	chr12_54235514_-	SINE	Alu	AluY
CAediting_894400	chr12_54235610_-	SINE	Alu	AluY
CAediting_894401	chr12_54235612_-	SINE	Alu	AluY
CAediting_894402	chr12_54237933_-	SINE	Alu	AluSc
CAediting_894403	chr12_54237935_-	SINE	Alu	AluSc
CAediting_894404	chr12_54237947_-	SINE	Alu	AluSc
CAediting_894405	chr12_54237948_-	SINE	Alu	AluSc
CAediting_894406	chr12_54237949_-	SINE	Alu	AluSc
CAediting_894407	chr12_54237978_-	SINE	Alu	AluSc
CAediting_894408	chr12_54238024_-	SINE	Alu	AluSc
CAediting_894409	chr12_54238052_-	SINE	Alu	AluSc
CAediting_894410	chr12_54238078_-	SINE	Alu	AluSc
CAediting_894411	chr12_54238090_-	SINE	Alu	AluSc
CAediting_894412	chr12_54238107_-	SINE	Alu	AluSc
CAediting_894413	chr12_54238108_-	SINE	Alu	AluSc
CAediting_894414	chr12_54238157_-	SINE	Alu	AluSc
CAediting_894415	chr12_54238181_-	SINE	Alu	AluSc
CAediting_894416	chr12_54238183_-	SINE	Alu	AluSc
CAediting_894417	chr12_54238187_-	SINE	Alu	AluSc
CAediting_894418	chr12_54240426_-	SINE	Alu	AluJr
CAediting_894419	chr12_54240451_-	SINE	Alu	AluJr
CAediting_894420	chr12_54240452_-	SINE	Alu	AluJr
CAediting_894421	chr12_54240458_-	SINE	Alu	AluJr
CAediting_894422	chr12_54240459_-	SINE	Alu	AluJr
CAediting_894423	chr12_54240467_-	SINE	Alu	AluJr
CAediting_894424	chr12_54240470_-	SINE	Alu	AluJr
CAediting_894425	chr12_54240477_-	SINE	Alu	AluJr
CAediting_894426	chr12_54240483_-	SINE	Alu	AluJr
CAediting_894427	chr12_54240491_-	SINE	Alu	AluJr
CAediting_894428	chr12_54240494_-	SINE	Alu	AluJr
CAediting_894429	chr12_54240500_-	SINE	Alu	AluJr
CAediting_894430	chr12_54240509_-	SINE	Alu	AluJr
CAediting_894431	chr12_54240516_-	SINE	Alu	AluJr
CAediting_894432	chr12_54240518_-	SINE	Alu	AluJr
CAediting_894433	chr12_54240522_-	SINE	Alu	AluJr
CAediting_894434	chr12_54245088_-	SINE	Alu	AluSz
CAediting_894435	chr12_54245140_-	SINE	Alu	AluSz
CAediting_894436	chr12_54245175_-	SINE	Alu	AluSz
CAediting_894437	chr12_54248005_-	SINE	Alu	AluSx
CAediting_894438	chr12_54249126_-	SINE	Alu	AluSc8
CAediting_894439	chr12_54254214_-	SINE	Alu	AluYc
CAediting_894440	chr12_54261370_-	SINE	Alu	AluSc5
CAediting_894441	chr12_54261559_-	SINE	Alu	AluSc5

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RNA A-to-I editing events in the alternative splicing sites for CBX5

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
IR	CAediting_894372	chr12_54233814_-	54233810:54233832	3SS	0+2i	CCAAGCAGCTGGGACTACAGGCG	-5.45	CCAAGCAGCTGGGACTACGGGCG	-13.41
IR	CAediting_894373	chr12_54233816_-	54233810:54233832	3SS	0+4i	CCAAGCAGCTGGGACTACAGGCG	-5.45	CCAAGCAGCTGGGACTGCAGGCG	-4.34
IR	CAediting_894374	chr12_54233829_-	54233810:54233832	3SS	0+17i	CCAAGCAGCTGGGACTACAGGCG	-5.45	CCAGGCAGCTGGGACTACAGGCG	-4.97
IR	CAediting_894375	chr12_54233830_-	54233810:54233832	3SS	0+18i	CCAAGCAGCTGGGACTACAGGCG	-5.45	CCGAGCAGCTGGGACTACAGGCG	-5.46

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000094916.12.CBX5.

Correlation between RNA A-to-I editing and PSI for ENSG00000094916.12.CBX5.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CBX5

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

BRCA.CAediting_894417.ENSG00000094916.CBX5.png
Soverview

PRAD.CAediting_894431.ENSG00000094916.CBX5.png
Soverview

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Protein coding region RNA A-to-I editings for CBX5

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for CBX5

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1229414	chr17_67471546_+	ENSG00000094916.12	ENST00000439541	hsa-miR-548aa	54241191	54241197	7mer-m8	54241190	54241216	153	-17.15
CAediting_1351755	chr19_40282625_-	ENSG00000094916.12	ENST00000439541	hsa-miR-641	54240640	54240646	7mer-m8	54240639	54240664	153	-16.68
CAediting_1399425	chr20_1392958_-	ENSG00000094916.12	ENST00000439541	hsa-miR-6869-5p	54241220	54241226	7mer-m8	54241219	54241240	148	-20.55
CAediting_1399425	chr20_1392958_-	ENSG00000094916.12	ENST00000439541	hsa-miR-6869-5p	54241681	54241687	7mer-m8	54241680	54241701	152	-23.46
CAediting_396018	chr5_1062918_-	ENSG00000094916.12	ENST00000439541	hsa-miR-4635	54241465	54241472	8mer-1a	54241465	54241485	157	-20.63

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_980496	chr14_31014685_-	ENSG00000094916.12	ENST00000439541	hsa-miR-624-3p	54241233	54241239	7mer-m8	54241232	54241251	145	-14.14

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CBX5

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for CBX5

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BRCA	CAediting_894429	chr12_54240500_-	1.07441105934684e-13	0.3301550572355	.	.	.	.
LUAD	CAediting_894429	chr12_54240500_-	0.00121790479070097	0.295508686306188	.	.	.	.
HNSC	CAediting_894429	chr12_54240500_-	1.83311638066197e-05	0.320359572281649	.	.	.	.
STAD	CAediting_894429	chr12_54240500_-	3.16152817062258e-10	0.395602969853515	.	.	.	.
ESCA	CAediting_894429	chr12_54240500_-	0.0026237341207252	0.264813493482847	.	.	.	.
OV	CAediting_894429	chr12_54240500_-	5.60389701674872e-05	0.255984450621554	.	.	.	.
LGG	CAediting_894431	chr12_54240516_-	0.00298732066871746	0.303052013092655	.	.	.	.
BRCA	CAediting_894431	chr12_54240516_-	1.52103529027274e-07	0.258196958016223	.	.	.	.
HNSC	CAediting_894431	chr12_54240516_-	.	.	0.0339025080923548	0.233151900393978	.	.
STAD	CAediting_894431	chr12_54240516_-	0.0323639828333723	0.16048082642275	.	.	.	.
ESCA	CAediting_894431	chr12_54240516_-	0.017622647446748	0.230155151588143	.	.	.	.
OV	CAediting_894431	chr12_54240516_-	3.914858913149e-07	0.334777731572015	.	.	.	.

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Relation with cancer stages for CBX5

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BRCA	pathologic_stage	CAediting_894429	chr12_54240500_-	0.0289880855184279	-0.100951168870734
HNSC	clinical_stage	CAediting_894431	chr12_54240516_-	0.00650194680215464	-0.29645443890841
HNSC	pathologic_stage	CAediting_894431	chr12_54240516_-	0.0313094560302025	-0.244033731657261
LUAD	pathologic_stage	CAediting_894431	chr12_54240516_-	0.0330767458870916	0.20156432734833
THCA	pathologic_stage	CAediting_894429	chr12_54240500_-	0.0381926417222988	0.159605685256629

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Relation with survival for CBX5

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
CESC	CAediting_894403	chr12_54237935_-	0.0365167502633286	0.00885786	26798.5
OV	CAediting_894403	chr12_54237935_-	0.0257113412903748	0.0311821	0.0208365

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RelatedDrugs for CBX5

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
CBX5	P45973	DB09130	Copper	Chromobox protein homolog 5	SmallMoleculeDrug	approved\|investigational

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RelatedDiseases for CBX5

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
CBX5	C0009402	Colorectal Carcinoma	1	CTD_human
CBX5	C0009404	Colorectal Neoplasms	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene