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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: VPS8 (CAeditome ID:23355)

Gene summary for VPS8

check button Gene summary
Gene informationGene symbol

VPS8

Gene ID

23355

Gene nameVPS8 subunit of CORVET complex
SynonymsKIAA0804
Cytomap

3q27.2

Type of geneprotein-coding
Descriptionvacuolar protein sorting-associated protein 8 homologVPS8, CORVET complex subunitvacuolar protein sorting 8 homolog
Modification date20210518
UniProtAcc

Q8N3P4

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
VPS8

GO:0005769

Vacuolar protein sorting-associated protein 8 homolog

25266290


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RNA A-to-I events for VPS8

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000156931.14

check button RNA A-to-I editing events in Cancer.
CAediting_329633(184818450, +), CAediting_329634(184818454, +), CAediting_329635(184818464, +), CAediting_329636(184840437, +), CAediting_329637(184840445, +), CAediting_329638(184840491, +), CAediting_329639(184840566, +), CAediting_329640(184840597, +), CAediting_329641(184842099, +), CAediting_329642(184842108, +), CAediting_329643(184844158, +), CAediting_329644(184844180, +), CAediting_329645(184844197, +), CAediting_329646(184844212, +), CAediting_329647(184844301, +), CAediting_329648(184844306, +), CAediting_329649(184844346, +), CAediting_329650(184844371, +), CAediting_329651(184845488, +), CAediting_329652(184845504, +), CAediting_329653(184845505, +), CAediting_329654(184845531, +), CAediting_329655(184845544, +), CAediting_329656(184845545, +), CAediting_329657(184845608, +), CAediting_329658(184845634, +), CAediting_329659(184845635, +), CAediting_329660(184845640, +), CAediting_329661(184845669, +), CAediting_329662(184845676, +), CAediting_329663(184845700, +), CAediting_329664(184845705, +), CAediting_329665(184847957, +), CAediting_329666(184847968, +), CAediting_329667(184847982, +), CAediting_329668(184847993, +), CAediting_329669(184848012, +), CAediting_329670(184848013, +), CAediting_329671(184848016, +), CAediting_329672(184848030, +), CAediting_329673(184848042, +), CAediting_329674(184848046, +), CAediting_329675(184848092, +), CAediting_329676(184848147, +), CAediting_329677(184848165, +), CAediting_329678(184848803, +), CAediting_329679(184850544, +), CAediting_329680(184875777, +), CAediting_329681(184875869, +), CAediting_329682(184887240, +), CAediting_329683(184903505, +), CAediting_329684(184915694, +), CAediting_329685(184924388, +), CAediting_329686(184934192, +), CAediting_329687(184934311, +), CAediting_329688(184934354, +), CAediting_329689(184934360, +), CAediting_329690(184934433, +), CAediting_329691(184934439, +), CAediting_329692(184936879, +), CAediting_329693(184938766, +), CAediting_329694(184938770, +), CAediting_329695(184938773, +), CAediting_329696(184938803, +), CAediting_329697(184938827, +), CAediting_329698(184938841, +), CAediting_329699(184938842, +), CAediting_329700(184938857, +), CAediting_329701(184938868, +), CAediting_329702(184938869, +), CAediting_329703(184938870, +), CAediting_329704(184938879, +), CAediting_329705(184938880, +), CAediting_329706(184938883, +), CAediting_329707(184938932, +), CAediting_329708(184938951, +), CAediting_329709(184950039, +), CAediting_329710(184967216, +), CAediting_329711(184967684, +), CAediting_329712(184967690, +), CAediting_329713(184967716, +), CAediting_329714(184983929, +), CAediting_329715(184983930, +), CAediting_329716(184983935, +), CAediting_329717(184983938, +), CAediting_329718(184983947, +), CAediting_329719(184983997, +), CAediting_329720(184984006, +), CAediting_329721(184984007, +), CAediting_329722(184984053, +), CAediting_329723(184984063, +), CAediting_329724(184984069, +), CAediting_329725(184984073, +), CAediting_329726(184984090, +), CAediting_329727(184984104, +), CAediting_329728(184984105, +), CAediting_329729(184984116, +), CAediting_329730(184984394, +), CAediting_329731(184984433, +), CAediting_329732(184984435, +), CAediting_329733(184984493, +), CAediting_329734(184984545, +), CAediting_329735(184984554, +), CAediting_329736(184984567, +), CAediting_329737(184984573, +), CAediting_329738(185020574, +), CAediting_329739(185020601, +), CAediting_329740(185020605, +), CAediting_329741(185020731, +), CAediting_329742(185026894, +), CAediting_329743(185026931, +), CAediting_329744(185026961, +), CAediting_329745(185045688, +),

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RNA editing positional annotations for VPS8 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_329633chr3_184818450_+intronic
CAediting_329634chr3_184818454_+intronic
CAediting_329635chr3_184818464_+intronic
CAediting_329636chr3_184840437_+ncRNA_intronic
CAediting_329637chr3_184840445_+ncRNA_intronic
CAediting_329638chr3_184840491_+ncRNA_intronic
CAediting_329639chr3_184840566_+ncRNA_intronic
CAediting_329640chr3_184840597_+ncRNA_intronic
CAediting_329641chr3_184842099_+ncRNA_intronic
CAediting_329642chr3_184842108_+ncRNA_intronic
CAediting_329643chr3_184844158_+ncRNA_intronic
CAediting_329644chr3_184844180_+ncRNA_intronic
CAediting_329645chr3_184844197_+ncRNA_intronic
CAediting_329646chr3_184844212_+ncRNA_intronic
CAediting_329647chr3_184844301_+ncRNA_intronic
CAediting_329648chr3_184844306_+ncRNA_intronic
CAediting_329649chr3_184844346_+ncRNA_intronic
CAediting_329650chr3_184844371_+ncRNA_intronic
CAediting_329651chr3_184845488_+ncRNA_intronic
CAediting_329652chr3_184845504_+ncRNA_intronic
CAediting_329653chr3_184845505_+ncRNA_intronic
CAediting_329654chr3_184845531_+ncRNA_intronic
CAediting_329655chr3_184845544_+ncRNA_intronic
CAediting_329656chr3_184845545_+ncRNA_intronic
CAediting_329657chr3_184845608_+ncRNA_intronic
CAediting_329658chr3_184845634_+ncRNA_intronic
CAediting_329659chr3_184845635_+ncRNA_intronic
CAediting_329660chr3_184845640_+ncRNA_intronic
CAediting_329661chr3_184845669_+ncRNA_intronic
CAediting_329662chr3_184845676_+ncRNA_intronic
CAediting_329663chr3_184845700_+ncRNA_intronic
CAediting_329664chr3_184845705_+ncRNA_intronic
CAediting_329665chr3_184847957_+ncRNA_intronic
CAediting_329666chr3_184847968_+ncRNA_intronic
CAediting_329667chr3_184847982_+ncRNA_intronic
CAediting_329668chr3_184847993_+ncRNA_intronic
CAediting_329669chr3_184848012_+ncRNA_intronic
CAediting_329670chr3_184848013_+ncRNA_intronic
CAediting_329671chr3_184848016_+ncRNA_intronic
CAediting_329672chr3_184848030_+ncRNA_intronic
CAediting_329673chr3_184848042_+ncRNA_intronic
CAediting_329674chr3_184848046_+ncRNA_intronic
CAediting_329675chr3_184848092_+ncRNA_intronic
CAediting_329676chr3_184848147_+ncRNA_intronic
CAediting_329677chr3_184848165_+ncRNA_intronic
CAediting_329678chr3_184848803_+ncRNA_intronic
CAediting_329679chr3_184850544_+ncRNA_intronic
CAediting_329680chr3_184875777_+intronic
CAediting_329681chr3_184875869_+intronic
CAediting_329682chr3_184887240_+ncRNA_intronic
CAediting_329683chr3_184903505_+ncRNA_intronic
CAediting_329684chr3_184915694_+ncRNA_intronic
CAediting_329685chr3_184924388_+ncRNA_intronic
CAediting_329686chr3_184934192_+ncRNA_intronic
CAediting_329687chr3_184934311_+ncRNA_intronic
CAediting_329688chr3_184934354_+ncRNA_intronic
CAediting_329689chr3_184934360_+ncRNA_intronic
CAediting_329690chr3_184934433_+ncRNA_intronic
CAediting_329691chr3_184934439_+ncRNA_intronic
CAediting_329692chr3_184936879_+ncRNA_intronic
CAediting_329693chr3_184938766_+ncRNA_intronic
CAediting_329694chr3_184938770_+ncRNA_intronic
CAediting_329695chr3_184938773_+ncRNA_intronic
CAediting_329696chr3_184938803_+ncRNA_intronic
CAediting_329697chr3_184938827_+ncRNA_intronic
CAediting_329698chr3_184938841_+ncRNA_intronic
CAediting_329699chr3_184938842_+ncRNA_intronic
CAediting_329700chr3_184938857_+ncRNA_intronic
CAediting_329701chr3_184938868_+ncRNA_intronic
CAediting_329702chr3_184938869_+ncRNA_intronic
CAediting_329703chr3_184938870_+ncRNA_intronic
CAediting_329704chr3_184938879_+ncRNA_intronic
CAediting_329705chr3_184938880_+ncRNA_intronic
CAediting_329706chr3_184938883_+ncRNA_intronic
CAediting_329707chr3_184938932_+ncRNA_intronic
CAediting_329708chr3_184938951_+ncRNA_intronic
CAediting_329709chr3_184950039_+ncRNA_intronic
CAediting_329710chr3_184967216_+ncRNA_intronic
CAediting_329711chr3_184967684_+ncRNA_intronic
CAediting_329712chr3_184967690_+ncRNA_intronic
CAediting_329713chr3_184967716_+ncRNA_intronic
CAediting_329714chr3_184983929_+ncRNA_intronic
CAediting_329715chr3_184983930_+ncRNA_intronic
CAediting_329716chr3_184983935_+ncRNA_intronic
CAediting_329717chr3_184983938_+ncRNA_intronic
CAediting_329718chr3_184983947_+ncRNA_intronic
CAediting_329719chr3_184983997_+ncRNA_intronic
CAediting_329720chr3_184984006_+ncRNA_intronic
CAediting_329721chr3_184984007_+ncRNA_intronic
CAediting_329722chr3_184984053_+ncRNA_intronic
CAediting_329723chr3_184984063_+ncRNA_intronic
CAediting_329724chr3_184984069_+ncRNA_intronic
CAediting_329725chr3_184984073_+ncRNA_intronic
CAediting_329726chr3_184984090_+ncRNA_intronic
CAediting_329727chr3_184984104_+ncRNA_intronic
CAediting_329728chr3_184984105_+ncRNA_intronic
CAediting_329729chr3_184984116_+ncRNA_intronic
CAediting_329730chr3_184984394_+ncRNA_intronic
CAediting_329731chr3_184984433_+ncRNA_intronic
CAediting_329732chr3_184984435_+ncRNA_intronic
CAediting_329733chr3_184984493_+ncRNA_intronic
CAediting_329734chr3_184984545_+ncRNA_intronic
CAediting_329735chr3_184984554_+ncRNA_intronic
CAediting_329736chr3_184984567_+ncRNA_intronic
CAediting_329737chr3_184984573_+ncRNA_intronic
CAediting_329738chr3_185020574_+ncRNA_intronic
CAediting_329739chr3_185020601_+ncRNA_intronic
CAediting_329740chr3_185020605_+ncRNA_intronic
CAediting_329741chr3_185020731_+ncRNA_intronic
CAediting_329742chr3_185026894_+ncRNA_intronic
CAediting_329743chr3_185026931_+ncRNA_intronic
CAediting_329744chr3_185026961_+ncRNA_intronic
CAediting_329745chr3_185045688_+ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_329633chr3_184818450_+SINEAluAluSx3
CAediting_329634chr3_184818454_+SINEAluAluSx3
CAediting_329635chr3_184818464_+SINEAluAluSx3
CAediting_329636chr3_184840437_+SINEAluAluSx1
CAediting_329637chr3_184840445_+SINEAluAluSx1
CAediting_329638chr3_184840491_+SINEAluAluSx1
CAediting_329639chr3_184840566_+SINEAluAluSx1
CAediting_329640chr3_184840597_+SINEAluAluSx1
CAediting_329641chr3_184842099_+SINEAluAluYc
CAediting_329642chr3_184842108_+SINEAluAluYc
CAediting_329643chr3_184844158_+SINEAluAluSz
CAediting_329644chr3_184844180_+SINEAluAluSz
CAediting_329645chr3_184844197_+SINEAluAluSz
CAediting_329646chr3_184844212_+SINEAluAluSz
CAediting_329647chr3_184844301_+SINEAluAluSz
CAediting_329648chr3_184844306_+SINEAluAluSz
CAediting_329649chr3_184844346_+SINEAluAluSz
CAediting_329650chr3_184844371_+SINEAluAluSz
CAediting_329651chr3_184845488_+SINEAluAluSp
CAediting_329652chr3_184845504_+SINEAluAluSp
CAediting_329653chr3_184845505_+SINEAluAluSp
CAediting_329654chr3_184845531_+SINEAluAluSp
CAediting_329655chr3_184845544_+SINEAluAluSp
CAediting_329656chr3_184845545_+SINEAluAluSp
CAediting_329657chr3_184845608_+SINEAluAluSp
CAediting_329658chr3_184845634_+SINEAluAluSp
CAediting_329659chr3_184845635_+SINEAluAluSp
CAediting_329660chr3_184845640_+SINEAluAluSp
CAediting_329661chr3_184845669_+SINEAluAluSp
CAediting_329662chr3_184845676_+SINEAluAluSp
CAediting_329663chr3_184845700_+SINEAluAluSp
CAediting_329664chr3_184845705_+SINEAluAluSp
CAediting_329665chr3_184847957_+SINEAluAluSx1
CAediting_329666chr3_184847968_+SINEAluAluSx1
CAediting_329667chr3_184847982_+SINEAluAluSx1
CAediting_329668chr3_184847993_+SINEAluAluSx1
CAediting_329669chr3_184848012_+SINEAluAluSx1
CAediting_329670chr3_184848013_+SINEAluAluSx1
CAediting_329671chr3_184848016_+SINEAluAluSx1
CAediting_329672chr3_184848030_+SINEAluAluSx1
CAediting_329673chr3_184848042_+SINEAluAluSx1
CAediting_329674chr3_184848046_+SINEAluAluSx1
CAediting_329675chr3_184848092_+SINEAluAluSx1
CAediting_329676chr3_184848147_+SINEAluAluSx1
CAediting_329677chr3_184848165_+SINEAluAluSx1
CAediting_329678chr3_184848803_+SINEAluAluSx
CAediting_329680chr3_184875777_+SINEAluAluJb
CAediting_329681chr3_184875869_+SINEAluAluJb
CAediting_329682chr3_184887240_+SINEAluAluJr
CAediting_329683chr3_184903505_+SINEAluAluJr
CAediting_329684chr3_184915694_+SINEAluAluSx1
CAediting_329685chr3_184924388_+SINEAluAluSx
CAediting_329686chr3_184934192_+SINEAluAluSz6
CAediting_329687chr3_184934311_+SINEAluAluSz6
CAediting_329688chr3_184934354_+SINEAluAluSz6
CAediting_329689chr3_184934360_+SINEAluAluSz6
CAediting_329690chr3_184934433_+SINEAluAluSz6
CAediting_329691chr3_184934439_+SINEAluAluSz6
CAediting_329692chr3_184936879_+SINEAluAluY
CAediting_329693chr3_184938766_+SINEAluAluJb
CAediting_329694chr3_184938770_+SINEAluAluJb
CAediting_329695chr3_184938773_+SINEAluAluJb
CAediting_329696chr3_184938803_+SINEAluAluJb
CAediting_329697chr3_184938827_+SINEAluAluJb
CAediting_329698chr3_184938841_+SINEAluAluJb
CAediting_329699chr3_184938842_+SINEAluAluJb
CAediting_329700chr3_184938857_+SINEAluAluJb
CAediting_329701chr3_184938868_+SINEAluAluJb
CAediting_329702chr3_184938869_+SINEAluAluJb
CAediting_329703chr3_184938870_+SINEAluAluJb
CAediting_329704chr3_184938879_+SINEAluAluJb
CAediting_329705chr3_184938880_+SINEAluAluJb
CAediting_329706chr3_184938883_+SINEAluAluJb
CAediting_329707chr3_184938932_+SINEAluAluJb
CAediting_329708chr3_184938951_+SINEAluAluJb
CAediting_329709chr3_184950039_+SINEAluAluSz
CAediting_329710chr3_184967216_+SINEAluAluJb
CAediting_329711chr3_184967684_+SINEAluAluSx
CAediting_329712chr3_184967690_+SINEAluAluSx
CAediting_329713chr3_184967716_+SINEAluAluSx
CAediting_329714chr3_184983929_+SINEAluAluY
CAediting_329715chr3_184983930_+SINEAluAluY
CAediting_329716chr3_184983935_+SINEAluAluY
CAediting_329717chr3_184983938_+SINEAluAluY
CAediting_329718chr3_184983947_+SINEAluAluY
CAediting_329719chr3_184983997_+SINEAluAluY
CAediting_329720chr3_184984006_+SINEAluAluY
CAediting_329721chr3_184984007_+SINEAluAluY
CAediting_329722chr3_184984053_+SINEAluAluY
CAediting_329723chr3_184984063_+SINEAluAluY
CAediting_329724chr3_184984069_+SINEAluAluY
CAediting_329725chr3_184984073_+SINEAluAluY
CAediting_329726chr3_184984090_+SINEAluAluY
CAediting_329727chr3_184984104_+SINEAluAluY
CAediting_329728chr3_184984105_+SINEAluAluY
CAediting_329729chr3_184984116_+SINEAluAluY
CAediting_329730chr3_184984394_+SINEAluAluSp
CAediting_329731chr3_184984433_+SINEAluAluSp
CAediting_329732chr3_184984435_+SINEAluAluSp
CAediting_329733chr3_184984493_+SINEAluAluSp
CAediting_329734chr3_184984545_+SINEAluAluSp
CAediting_329735chr3_184984554_+SINEAluAluSp
CAediting_329736chr3_184984567_+SINEAluAluSp
CAediting_329737chr3_184984573_+SINEAluAluSp
CAediting_329738chr3_185020574_+SINEAluAluJb
CAediting_329739chr3_185020601_+SINEAluAluJb
CAediting_329740chr3_185020605_+SINEAluAluJb
CAediting_329741chr3_185020731_+SINEAluAluJb
CAediting_329742chr3_185026894_+SINEAluAluSx3
CAediting_329743chr3_185026931_+SINEAluAluSx3
CAediting_329744chr3_185026961_+SINEAluAluSx3
CAediting_329745chr3_185045688_+SINEAluAluSx

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RNA A-to-I editing events in the alternative splicing sites for VPS8

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000156931.14.VPS8.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000156931.14.VPS8.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for VPS8

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for VPS8

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for VPS8

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_329638chr3_184840491_+ENSG00000156931.14ENST00000424463hsa-miR-6793-3p1848404861848404938mer-1a184840474184840493142.00-18.22
CAediting_329636chr3_184840437_+ENSG00000156931.14ENST00000424463hsa-miR-46341848404341848404407mer-m8184840418184840441151.00-32.12
CAediting_329637chr3_184840445_+ENSG00000156931.14ENST00000424463hsa-miR-513a-5p1848404391848404457mer-m8184840429184840446144.00-16.68
CAediting_329637chr3_184840445_+ENSG00000156931.14ENST00000424463hsa-miR-513a-5p1848404391848404457mer-m8184840429184840446144.00-16.68

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_329637chr3_184840445_+ENSG00000156931.14ENST00000424463hsa-miR-10399-5p1848404401848404467mer-m8184840426184840447144-10.39
CAediting_329637chr3_184840445_+ENSG00000156931.14ENST00000424463hsa-miR-6504-3p1848404401848404467mer-m8184840426184840447148-14.48
CAediting_329636chr3_184840437_+ENSG00000156931.14ENST00000424463hsa-miR-6807-5p1848404301848404367mer-m8184840416184840437140-20.68
CAediting_329637chr3_184840445_+ENSG00000156931.14ENST00000424463hsa-miR-7151-3p1848404381848404458mer-1a184840425184840445144-16.51

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_688080chr9_63819626_+ENSG00000156931.14ENST00000424721hsa-miR-4477b1848261851848261917mer-m8184826172184826192149-9.25
CAediting_1054808chr15_66496985_-ENSG00000156931.14ENST00000287546hsa-miR-45121850520821850520887mer-m8185052067185052089159-30.85
CAediting_77128chr1_85133844_+ENSG00000156931.14ENST00000287546hsa-miR-4423-3p1850521551850521617mer-m8185052142185052162150-16.6
CAediting_604450chr7_133034877_-ENSG00000156931.14ENST00000287546hsa-miR-36541850522861850522927mer-m8185052274185052293151-20.91
CAediting_1054808chr15_66496985_-ENSG00000156931.14ENST00000436792hsa-miR-45121850520821850520887mer-m8185052067185052089159-30.85
CAediting_77128chr1_85133844_+ENSG00000156931.14ENST00000436792hsa-miR-4423-3p1850521551850521617mer-m8185052142185052162150-16.6
CAediting_604450chr7_133034877_-ENSG00000156931.14ENST00000436792hsa-miR-36541850522861850522927mer-m8185052274185052293151-20.91
CAediting_1054808chr15_66496985_-ENSG00000156931.14ENST00000446204hsa-miR-45121850520821850520887mer-m8185052067185052089159-30.85
CAediting_77128chr1_85133844_+ENSG00000156931.14ENST00000446204hsa-miR-4423-3p1850521551850521617mer-m8185052142185052162150-16.6
CAediting_604450chr7_133034877_-ENSG00000156931.14ENST00000446204hsa-miR-36541850522861850522927mer-m8185052274185052293151-20.91
CAediting_396018chr5_1062918_-ENSG00000156931.14ENST00000424721hsa-miR-46351848261861848261927mer-m8184826169184826193144-17.49
CAediting_1160181chr17_7017644_-ENSG00000156931.14ENST00000424721hsa-miR-195-3p1848327271848327326mer184832721184832743146-10.14
CAediting_1160181chr17_7017644_-ENSG00000156931.14ENST00000424721hsa-miR-195-3p1848327361848327438mer-1a184832721184832743146-10.14
CAediting_1054808chr15_66496985_-ENSG00000156931.14ENST00000424463hsa-miR-45121848392961848393027mer-m8184839282184839303149-18.48
CAediting_1229415chr17_67471547_+ENSG00000156931.14ENST00000424463hsa-miR-548aa1848392891848392968mer-1a184839270184839296146-9.84
CAediting_1229415chr17_67471547_+ENSG00000156931.14ENST00000424463hsa-miR-548aa1848397371848397448mer-1a184839718184839744150-13.05
CAediting_117844chr1_162342605_+ENSG00000156931.14ENST00000458721hsa-miR-556-3p1849135351849135428mer-1a184913521184913542150-12.63
CAediting_1351755chr19_40282625_-ENSG00000156931.14ENST00000452140hsa-miR-6411849249021849249087mer-m8184924886184924909140-13.72
CAediting_468389chr6_31355314_-ENSG00000156931.14ENST00000287546hsa-miR-6891-5p1850524001850524056mer185052387185052406140-22.84
CAediting_468389chr6_31355314_-ENSG00000156931.14ENST00000436792hsa-miR-6891-5p1850524001850524056mer185052387185052406140-22.84
CAediting_468389chr6_31355314_-ENSG00000156931.14ENST00000446204hsa-miR-6891-5p1850524001850524056mer185052387185052406140-22.84
CAediting_468389chr6_31355314_-ENSG00000156931.14ENST00000458721hsa-miR-6891-5p1849009391849009446mer184900929184900948158-22.21
CAediting_468389chr6_31355314_-ENSG00000156931.14ENST00000458721hsa-miR-6891-5p1849009411849009477mer-m8184900929184900948158-22.21

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_393chr1_1167164_+ENSG00000156931.14ENST00000424463hsa-miR-200b-3p1848391571848391637mer-m8184839143184839164145-11.98
CAediting_1351755chr19_40282625_-ENSG00000156931.14ENST00000424463hsa-miR-6411848392101848392156mer184839193184839216143-19.73

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for VPS8

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000424463.4protein_codingSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_329636ENST00000424463.4chr3_184840437_+-585.00-585.60-588.40
CAediting_329637ENST00000424463.4chr3_184840445_+-586.90-585.60-588.40
CAediting_329638ENST00000424463.4chr3_184840491_+-587.30-585.60-588.40

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Relation with ADAR for VPS8

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for VPS8

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for VPS8

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
STADCAediting_329661chr3_184845669_+0.002472529358569790.01381683136.64

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RelatedDrugs for VPS8

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for VPS8

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
VPS8C0003886Arthrogryposis3CLINGEN;GENOMICS_ENGLAND