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Editing gene: MPRIP (CAeditome ID:23164)

Gene summary for MPRIP

Gene summary

Gene information	Gene symbol	MPRIP
	Gene ID	23164
	Gene name	myosin phosphatase Rho interacting protein
	Synonyms	M-RIP\|MRIP\|RHOIP3\|RIP3\|p116Rip
	Cytomap	17p11.2
	Type of gene	protein-coding
	Description	myosin phosphatase Rho-interacting proteinRho interacting protein 3
	Modification date	20210518
	UniProtAcc	Q6WCQ1
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
MPRIP	GO:0005829	Myosin phosphatase Rho-interacting protein	0000052
MPRIP	GO:0015629	Myosin phosphatase Rho-interacting protein	0000052

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RNA A-to-I events for MPRIP

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000133030.18

RNA A-to-I editing events in Cancer.

CAediting_1166504(17046012, +), CAediting_1166505(17049032, +), CAediting_1166506(17049127, +), CAediting_1166507(17049146, +), CAediting_1166508(17056837, +), CAediting_1166509(17089478, +), CAediting_1166510(17097442, +), CAediting_1166511(17098383, +), CAediting_1166512(17102077, +), CAediting_1166513(17117508, +), CAediting_1166514(17118216, +), CAediting_1166515(17118222, +), CAediting_1166516(17118231, +), CAediting_1166517(17118293, +), CAediting_1166518(17118892, +), CAediting_1166519(17118893, +), CAediting_1166520(17118926, +), CAediting_1166521(17118969, +), CAediting_1166522(17118985, +), CAediting_1166523(17118988, +), CAediting_1166524(17122390, +), CAediting_1166525(17122774, +), CAediting_1166526(17122872, +), CAediting_1166527(17122977, +), CAediting_1166528(17122980, +), CAediting_1166529(17123413, +), CAediting_1166530(17123434, +), CAediting_1166531(17123476, +), CAediting_1166532(17123477, +), CAediting_1166533(17123542, +), CAediting_1166534(17123570, +), CAediting_1166535(17123593, +), CAediting_1166536(17123624, +), CAediting_1166537(17123625, +), CAediting_1166538(17123629, +), CAediting_1166539(17123659, +), CAediting_1166540(17123661, +), CAediting_1166541(17149239, +), CAediting_1166542(17149391, +), CAediting_1166543(17155356, +), CAediting_1166544(17155436, +), CAediting_1166545(17155453, +), CAediting_1166546(17186592, +), CAediting_1166547(17186598, +), CAediting_1166548(17186604, +), CAediting_1166549(17186608, +), CAediting_1166550(17186612, +), CAediting_1166551(17186621, +), CAediting_1166552(17186625, +), CAediting_1166553(17186628, +), CAediting_1166554(17186639, +), CAediting_1166555(17186668, +), CAediting_1166556(17186684, +), CAediting_1166557(17186702, +), CAediting_1166558(17186703, +), CAediting_1166559(17186706, +), CAediting_1166560(17186721, +), CAediting_1166561(17189207, +), CAediting_1166562(17189210, +), CAediting_1166563(17189212, +), CAediting_1166564(17189214, +), CAediting_1166565(17189232, +), CAediting_1166566(17189263, +), CAediting_1166567(17189268, +), CAediting_1166568(17189269, +), CAediting_1166569(17189282, +), CAediting_1166570(17189293, +), CAediting_1166571(17189306, +), CAediting_1166572(17189315, +), CAediting_1166573(17189318, +), CAediting_1166574(17189328, +), CAediting_1166575(17189330, +), CAediting_1166576(17189354, +), CAediting_1166577(17189355, +), CAediting_1166578(17189371, +), CAediting_1166579(17189391, +), CAediting_1166580(17189400, +), CAediting_1166581(17189449, +), CAediting_1166582(17189450, +), CAediting_1166583(17189451, +), CAediting_1166584(17189463, +), CAediting_1166585(17189476, +), CAediting_1166586(17189479, +), CAediting_1166587(17193107, +), CAediting_1166588(17194294, +), CAediting_1166589(17194301, +), CAediting_1166590(17194393, +), CAediting_1166591(17194584, +), CAediting_1166592(17195435, +), CAediting_1166593(17199831, +),

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RNA editing positional annotations for MPRIP using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1166504	chr17_17046012_+	ncRNA_intronic
CAediting_1166505	chr17_17049032_+	ncRNA_intronic
CAediting_1166506	chr17_17049127_+	ncRNA_intronic
CAediting_1166507	chr17_17049146_+	ncRNA_intronic
CAediting_1166508	chr17_17056837_+	ncRNA_intronic
CAediting_1166509	chr17_17089478_+	ncRNA_intronic
CAediting_1166510	chr17_17097442_+	intronic
CAediting_1166511	chr17_17098383_+	intronic
CAediting_1166512	chr17_17102077_+	intronic
CAediting_1166513	chr17_17117508_+	intronic
CAediting_1166514	chr17_17118216_+	intronic
CAediting_1166515	chr17_17118222_+	intronic
CAediting_1166516	chr17_17118231_+	intronic
CAediting_1166517	chr17_17118293_+	intronic
CAediting_1166518	chr17_17118892_+	intronic
CAediting_1166519	chr17_17118893_+	intronic
CAediting_1166520	chr17_17118926_+	intronic
CAediting_1166521	chr17_17118969_+	intronic
CAediting_1166522	chr17_17118985_+	intronic
CAediting_1166523	chr17_17118988_+	intronic
CAediting_1166524	chr17_17122390_+	intronic
CAediting_1166525	chr17_17122774_+	intronic
CAediting_1166526	chr17_17122872_+	intronic
CAediting_1166527	chr17_17122977_+	intronic
CAediting_1166528	chr17_17122980_+	intronic
CAediting_1166529	chr17_17123413_+	intronic
CAediting_1166530	chr17_17123434_+	intronic
CAediting_1166531	chr17_17123476_+	intronic
CAediting_1166532	chr17_17123477_+	intronic
CAediting_1166533	chr17_17123542_+	intronic
CAediting_1166534	chr17_17123570_+	intronic
CAediting_1166535	chr17_17123593_+	intronic
CAediting_1166536	chr17_17123624_+	intronic
CAediting_1166537	chr17_17123625_+	intronic
CAediting_1166538	chr17_17123629_+	intronic
CAediting_1166539	chr17_17123659_+	intronic
CAediting_1166540	chr17_17123661_+	intronic
CAediting_1166541	chr17_17149239_+	intronic
CAediting_1166542	chr17_17149391_+	intronic
CAediting_1166543	chr17_17155356_+	ncRNA_intronic
CAediting_1166544	chr17_17155436_+	ncRNA_intronic
CAediting_1166545	chr17_17155453_+	ncRNA_intronic
CAediting_1166546	chr17_17186592_+	ncRNA_exonic
CAediting_1166547	chr17_17186598_+	ncRNA_exonic
CAediting_1166548	chr17_17186604_+	ncRNA_exonic
CAediting_1166549	chr17_17186608_+	ncRNA_exonic
CAediting_1166550	chr17_17186612_+	ncRNA_exonic
CAediting_1166551	chr17_17186621_+	ncRNA_exonic
CAediting_1166552	chr17_17186625_+	ncRNA_exonic
CAediting_1166553	chr17_17186628_+	ncRNA_exonic
CAediting_1166554	chr17_17186639_+	ncRNA_exonic
CAediting_1166555	chr17_17186668_+	ncRNA_intronic
CAediting_1166556	chr17_17186684_+	ncRNA_intronic
CAediting_1166557	chr17_17186702_+	ncRNA_intronic
CAediting_1166558	chr17_17186703_+	ncRNA_intronic
CAediting_1166559	chr17_17186706_+	ncRNA_intronic
CAediting_1166560	chr17_17186721_+	ncRNA_intronic
CAediting_1166561	chr17_17189207_+	ncRNA_intronic
CAediting_1166562	chr17_17189210_+	ncRNA_intronic
CAediting_1166563	chr17_17189212_+	ncRNA_intronic
CAediting_1166564	chr17_17189214_+	ncRNA_intronic
CAediting_1166565	chr17_17189232_+	ncRNA_intronic
CAediting_1166566	chr17_17189263_+	ncRNA_exonic
CAediting_1166567	chr17_17189268_+	ncRNA_exonic
CAediting_1166568	chr17_17189269_+	ncRNA_exonic
CAediting_1166569	chr17_17189282_+	ncRNA_exonic
CAediting_1166570	chr17_17189293_+	ncRNA_exonic
CAediting_1166571	chr17_17189306_+	ncRNA_exonic
CAediting_1166572	chr17_17189315_+	ncRNA_exonic
CAediting_1166573	chr17_17189318_+	ncRNA_exonic
CAediting_1166574	chr17_17189328_+	ncRNA_exonic
CAediting_1166575	chr17_17189330_+	ncRNA_exonic
CAediting_1166576	chr17_17189354_+	ncRNA_exonic
CAediting_1166577	chr17_17189355_+	ncRNA_exonic
CAediting_1166578	chr17_17189371_+	ncRNA_exonic
CAediting_1166579	chr17_17189391_+	ncRNA_exonic
CAediting_1166580	chr17_17189400_+	ncRNA_exonic
CAediting_1166581	chr17_17189449_+	ncRNA_exonic
CAediting_1166582	chr17_17189450_+	ncRNA_exonic
CAediting_1166583	chr17_17189451_+	ncRNA_exonic
CAediting_1166584	chr17_17189463_+	ncRNA_exonic
CAediting_1166585	chr17_17189476_+	ncRNA_exonic
CAediting_1166586	chr17_17189479_+	ncRNA_exonic
CAediting_1166587	chr17_17193107_+	intronic
CAediting_1166588	chr17_17194294_+	intronic
CAediting_1166589	chr17_17194301_+	intronic
CAediting_1166590	chr17_17194393_+	intronic
CAediting_1166591	chr17_17194584_+	intronic
CAediting_1166592	chr17_17195435_+	intronic
CAediting_1166593	chr17_17199831_+	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1166504	chr17_17046012_+	SINE	Alu	AluY
CAediting_1166505	chr17_17049032_+	LINE	L1	L1MB5
CAediting_1166506	chr17_17049127_+	LINE	L1	L1MB5
CAediting_1166507	chr17_17049146_+	LINE	L1	L1MB5
CAediting_1166508	chr17_17056837_+	LINE	L1	L1MB5
CAediting_1166509	chr17_17089478_+	SINE	Alu	AluJo
CAediting_1166510	chr17_17097442_+	SINE	Alu	AluJr
CAediting_1166512	chr17_17102077_+	SINE	Alu	FLAM_C
CAediting_1166513	chr17_17117508_+	LINE	L1	L1MB5
CAediting_1166524	chr17_17122390_+	SINE	Alu	AluY
CAediting_1166525	chr17_17122774_+	LINE	L1	L1MB7
CAediting_1166526	chr17_17122872_+	LINE	L1	L1MB7
CAediting_1166527	chr17_17122977_+	LINE	L1	L1MB7
CAediting_1166528	chr17_17122980_+	LINE	L1	L1MB7
CAediting_1166529	chr17_17123413_+	SINE	Alu	AluSz
CAediting_1166530	chr17_17123434_+	SINE	Alu	AluSz
CAediting_1166531	chr17_17123476_+	SINE	Alu	AluSz
CAediting_1166532	chr17_17123477_+	SINE	Alu	AluSz
CAediting_1166533	chr17_17123542_+	SINE	Alu	AluSz
CAediting_1166534	chr17_17123570_+	SINE	Alu	AluSz
CAediting_1166535	chr17_17123593_+	SINE	Alu	AluSz
CAediting_1166536	chr17_17123624_+	SINE	Alu	AluSz
CAediting_1166537	chr17_17123625_+	SINE	Alu	AluSz
CAediting_1166538	chr17_17123629_+	SINE	Alu	AluSz
CAediting_1166539	chr17_17123659_+	SINE	Alu	AluSz
CAediting_1166540	chr17_17123661_+	SINE	Alu	AluSz
CAediting_1166541	chr17_17149239_+	SINE	Alu	AluSx1
CAediting_1166542	chr17_17149391_+	SINE	Alu	AluSx1
CAediting_1166543	chr17_17155356_+	SINE	Alu	AluSx
CAediting_1166544	chr17_17155436_+	SINE	Alu	AluSx
CAediting_1166545	chr17_17155453_+	SINE	Alu	AluSx
CAediting_1166547	chr17_17186598_+	SINE	Alu	AluJb
CAediting_1166548	chr17_17186604_+	SINE	Alu	AluJb
CAediting_1166549	chr17_17186608_+	SINE	Alu	AluJb
CAediting_1166550	chr17_17186612_+	SINE	Alu	AluJb
CAediting_1166551	chr17_17186621_+	SINE	Alu	AluJb
CAediting_1166552	chr17_17186625_+	SINE	Alu	AluJb
CAediting_1166553	chr17_17186628_+	SINE	Alu	AluJb
CAediting_1166554	chr17_17186639_+	SINE	Alu	AluJb
CAediting_1166555	chr17_17186668_+	SINE	Alu	AluJb
CAediting_1166556	chr17_17186684_+	SINE	Alu	AluJb
CAediting_1166557	chr17_17186702_+	SINE	Alu	AluJb
CAediting_1166558	chr17_17186703_+	SINE	Alu	AluJb
CAediting_1166559	chr17_17186706_+	SINE	Alu	AluJb
CAediting_1166560	chr17_17186721_+	SINE	Alu	AluJb
CAediting_1166561	chr17_17189207_+	SINE	Alu	AluY
CAediting_1166562	chr17_17189210_+	SINE	Alu	AluY
CAediting_1166563	chr17_17189212_+	SINE	Alu	AluY
CAediting_1166564	chr17_17189214_+	SINE	Alu	AluY
CAediting_1166565	chr17_17189232_+	SINE	Alu	AluY
CAediting_1166566	chr17_17189263_+	SINE	Alu	AluY
CAediting_1166567	chr17_17189268_+	SINE	Alu	AluY
CAediting_1166568	chr17_17189269_+	SINE	Alu	AluY
CAediting_1166569	chr17_17189282_+	SINE	Alu	AluY
CAediting_1166570	chr17_17189293_+	SINE	Alu	AluY
CAediting_1166571	chr17_17189306_+	SINE	Alu	AluY
CAediting_1166572	chr17_17189315_+	SINE	Alu	AluY
CAediting_1166573	chr17_17189318_+	SINE	Alu	AluY
CAediting_1166574	chr17_17189328_+	SINE	Alu	AluY
CAediting_1166575	chr17_17189330_+	SINE	Alu	AluY
CAediting_1166576	chr17_17189354_+	SINE	Alu	AluY
CAediting_1166577	chr17_17189355_+	SINE	Alu	AluY
CAediting_1166578	chr17_17189371_+	SINE	Alu	AluY
CAediting_1166579	chr17_17189391_+	SINE	Alu	AluY
CAediting_1166580	chr17_17189400_+	SINE	Alu	AluY
CAediting_1166581	chr17_17189449_+	SINE	Alu	AluY
CAediting_1166582	chr17_17189450_+	SINE	Alu	AluY
CAediting_1166583	chr17_17189451_+	SINE	Alu	AluY
CAediting_1166584	chr17_17189463_+	SINE	Alu	AluY
CAediting_1166585	chr17_17189476_+	SINE	Alu	AluY
CAediting_1166586	chr17_17189479_+	SINE	Alu	AluY
CAediting_1166587	chr17_17193107_+	SINE	Alu	AluJo
CAediting_1166588	chr17_17194294_+	SINE	Alu	AluSz6
CAediting_1166589	chr17_17194301_+	SINE	Alu	AluSz6
CAediting_1166590	chr17_17194393_+	SINE	Alu	AluSz6
CAediting_1166591	chr17_17194584_+	SINE	Alu	AluSz
CAediting_1166592	chr17_17195435_+	SINE	Alu	AluSx4
CAediting_1166593	chr17_17199831_+	SINE	Alu	AluYh3a3

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RNA A-to-I editing events in the alternative splicing sites for MPRIP

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
IR	CAediting_1166565	chr17_17189232_+	17189220:17189242	3SS	0+8i	GCTCTGTTGTCCAGGCTGGAGTG	-25.06	GCTCTGTTGTCCGGGCTGGAGTG	-17.49

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000133030.18.MPRIP.

Correlation between RNA A-to-I editing and PSI for ENSG00000133030.18.MPRIP.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MPRIP

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for MPRIP

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for MPRIP

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1166547	chr17_17186598_+	ENSG00000133030.18	ENST00000395811	hsa-miR-140-3p	17186593	17186599	7mer-m8	17186580	17186600	140.00	-14.69
CAediting_1166547	chr17_17186598_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3619-3p	17186596	17186601	6mer	17186579	17186602	142.00	-29.48
CAediting_1166559	chr17_17186706_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4790-5p	17186700	17186706	7mer-m8	17186688	17186707	158.00	-16.75
CAediting_1166559	chr17_17186706_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6744-3p	17186705	17186710	6mer	17186688	17186711	147.00	-32.99
CAediting_1166568	chr17_17189269_+	ENSG00000133030.18	ENST00000395811	hsa-miR-17-3p	17189262	17189268	7mer-m8	17189248	17189269	150.00	-16.31
CAediting_1166568	chr17_17189269_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3929	17189266	17189271	6mer	17189248	17189272	140.00	-25.35
CAediting_1166568	chr17_17189269_+	ENSG00000133030.18	ENST00000395811	hsa-miR-485-5p	17189266	17189272	7mer-m8	17189253	17189273	153.00	-20.87
CAediting_1166568	chr17_17189269_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6884-5p	17189266	17189272	7mer-m8	17189250	17189273	150.00	-25.70
CAediting_1166570	chr17_17189293_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4304	17189286	17189292	7mer-m8	17189276	17189293	150.00	-21.28
CAediting_1166574	chr17_17189328_+	ENSG00000133030.18	ENST00000395811	hsa-miR-17-3p	17189324	17189330	7mer-m8	17189309	17189331	154.00	-20.36
CAediting_1166581	chr17_17189449_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6771-5p	17189443	17189450	8mer-1a	17189431	17189450	157.00	-31.04
CAediting_1166583	chr17_17189451_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3189-3p	17189445	17189451	7mer-m8	17189433	17189452	141.00	-23.05
CAediting_1166583	chr17_17189451_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6813-3p	17189446	17189452	7mer-m8	17189433	17189453	140.00	-12.20
CAediting_1166546	chr17_17186592_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4691-3p	17186589	17186595	7mer-m8	17186573	17186596	159.00	-23.61
CAediting_1166549	chr17_17186608_+	ENSG00000133030.18	ENST00000395811	hsa-miR-1207-3p	17186601	17186607	7mer-m8	17186590	17186608	145.00	-13.82
CAediting_1166549	chr17_17186608_+	ENSG00000133030.18	ENST00000395811	hsa-miR-503-5p	17186604	17186609	6mer	17186585	17186610	140.00	-29.87
CAediting_1166549	chr17_17186608_+	ENSG00000133030.18	ENST00000395811	hsa-miR-646	17186603	17186609	7mer-m8	17186591	17186610	148.00	-19.42
CAediting_1166551	chr17_17186621_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6849-3p	17186614	17186620	7mer-m8	17186599	17186621	141.00	-14.90
CAediting_1166553	chr17_17186628_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3156-3p	17186624	17186630	7mer-m8	17186611	17186631	155.00	-20.06
CAediting_1166553	chr17_17186628_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3156-3p	17186624	17186630	7mer-m8	17186611	17186631	155.00	-20.06
CAediting_1166553	chr17_17186628_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4301	17186623	17186630	8mer-1a	17186610	17186630	163.00	-26.24
CAediting_1166553	chr17_17186628_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4999-3p	17186621	17186627	7mer-m8	17186609	17186628	147.00	-16.42
CAediting_1166554	chr17_17186639_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3136-3p	17186635	17186641	7mer-m8	17186621	17186642	164.00	-17.63
CAediting_1166554	chr17_17186639_+	ENSG00000133030.18	ENST00000395811	hsa-miR-7155-3p	17186635	17186641	7mer-m8	17186624	17186642	146.00	-20.04
CAediting_1166557	chr17_17186702_+	ENSG00000133030.18	ENST00000395811	hsa-miR-5691	17186699	17186706	8mer-1a	17186686	17186706	147.00	-19.02
CAediting_1166557	chr17_17186702_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6773-3p	17186695	17186702	8mer-1a	17186681	17186702	142.00	-15.63
CAediting_1166557	chr17_17186702_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6805-3p	17186699	17186706	8mer-1a	17186684	17186706	154.00	-21.46
CAediting_1166560	chr17_17186721_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3144-3p	17186718	17186724	7mer-m8	17186703	17186725	155.00	-16.84
CAediting_1166561	chr17_17189207_+	ENSG00000133030.18	ENST00000395811	hsa-miR-516a-5p	17189204	17189209	6mer	17189187	17189210	153.00	-16.87
CAediting_1166561	chr17_17189207_+	ENSG00000133030.18	ENST00000395811	hsa-miR-516a-5p	17189204	17189209	6mer	17189187	17189210	153.00	-16.87
CAediting_1166565	chr17_17189232_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3940-3p	17189229	17189235	7mer-m8	17189215	17189236	155.00	-26.33
CAediting_1166565	chr17_17189232_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4442	17189226	17189232	7mer-m8	17189217	17189233	158.00	-23.26
CAediting_1166569	chr17_17189282_+	ENSG00000133030.18	ENST00000395811	hsa-miR-1247-3p	17189277	17189283	7mer-m8	17189262	17189284	152.00	-24.12
CAediting_1166573	chr17_17189318_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4691-3p	17189315	17189321	7mer-m8	17189295	17189322	150.00	-26.36
CAediting_1166576	chr17_17189354_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3157-5p	17189348	17189354	7mer-m8	17189332	17189355	165.00	-26.56
CAediting_1166576	chr17_17189354_+	ENSG00000133030.18	ENST00000395811	hsa-miR-34a-3p	17189350	17189356	7mer-m8	17189336	17189357	147.00	-8.76
CAediting_1166577	chr17_17189355_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548ae-3p	17189353	17189359	7mer-m8	17189339	17189360	143.00	-8.00
CAediting_1166577	chr17_17189355_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548ae-3p	17189353	17189359	7mer-m8	17189339	17189360	143.00	-8.00
CAediting_1166577	chr17_17189355_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548ah-3p	17189353	17189359	7mer-m8	17189341	17189360	144.00	-7.23
CAediting_1166577	chr17_17189355_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548aj-3p	17189353	17189359	7mer-m8	17189339	17189360	143.00	-8.90
CAediting_1166577	chr17_17189355_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548aj-3p	17189353	17189359	7mer-m8	17189339	17189360	143.00	-8.90
CAediting_1166577	chr17_17189355_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548am-3p	17189353	17189359	7mer-m8	17189341	17189360	144.00	-7.23
CAediting_1166577	chr17_17189355_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548aq-3p	17189353	17189359	7mer-m8	17189338	17189360	143.00	-8.38
CAediting_1166577	chr17_17189355_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548j-3p	17189353	17189359	7mer-m8	17189340	17189360	141.00	-7.55
CAediting_1166577	chr17_17189355_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548x-3p	17189353	17189359	7mer-m8	17189340	17189360	143.00	-8.45
CAediting_1166577	chr17_17189355_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548x-3p	17189353	17189359	7mer-m8	17189340	17189360	143.00	-8.45
CAediting_1166577	chr17_17189355_+	ENSG00000133030.18	ENST00000395811	hsa-miR-7844-5p	17189351	17189357	7mer-m8	17189337	17189358	160.00	-22.22
CAediting_1166582	chr17_17189450_+	ENSG00000133030.18	ENST00000395811	hsa-miR-326	17189445	17189451	7mer-m8	17189433	17189452	140.00	-14.65
CAediting_1166582	chr17_17189450_+	ENSG00000133030.18	ENST00000395811	hsa-miR-330-5p	17189445	17189451	7mer-m8	17189431	17189452	140.00	-23.76
CAediting_1166582	chr17_17189450_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4314	17189444	17189450	7mer-m8	17189433	17189451	147.00	-29.31
CAediting_1166582	chr17_17189450_+	ENSG00000133030.18	ENST00000395811	hsa-miR-514a-5p	17189446	17189452	7mer-m8	17189430	17189453	148.00	-20.64
CAediting_1166582	chr17_17189450_+	ENSG00000133030.18	ENST00000395811	hsa-miR-514a-5p	17189446	17189452	7mer-m8	17189430	17189453	148.00	-20.64
CAediting_1166582	chr17_17189450_+	ENSG00000133030.18	ENST00000395811	hsa-miR-514a-5p	17189446	17189452	7mer-m8	17189430	17189453	148.00	-20.64
CAediting_1166584	chr17_17189463_+	ENSG00000133030.18	ENST00000395811	hsa-miR-106a-3p	17189459	17189464	6mer	17189444	17189465	141.00	-21.13
CAediting_1166585	chr17_17189476_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6770-3p	17189472	17189478	7mer-m8	17189458	17189479	154.00	-21.95
CAediting_1166585	chr17_17189476_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6770-3p	17189472	17189478	7mer-m8	17189458	17189479	154.00	-21.95
CAediting_1166585	chr17_17189476_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6770-3p	17189472	17189478	7mer-m8	17189458	17189479	154.00	-21.95
CAediting_1166562	chr17_17189210_+	ENSG00000133030.18	ENST00000395811	hsa-miR-5001-3p	17189207	17189213	7mer-m8	17189194	17189214	141.00	-14.70
CAediting_1166564	chr17_17189214_+	ENSG00000133030.18	ENST00000395811	hsa-miR-10a-5p	17189209	17189215	7mer-m8	17189194	17189216	140.00	-13.07
CAediting_1166564	chr17_17189214_+	ENSG00000133030.18	ENST00000395811	hsa-miR-10b-5p	17189209	17189215	7mer-m8	17189190	17189216	148.00	-13.41
CAediting_1166564	chr17_17189214_+	ENSG00000133030.18	ENST00000395811	hsa-miR-339-5p	17189208	17189214	7mer-m8	17189193	17189215	143.00	-15.37
CAediting_1166564	chr17_17189214_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4725-5p	17189210	17189216	7mer-m8	17189197	17189217	140.00	-17.11
CAediting_1166564	chr17_17189214_+	ENSG00000133030.18	ENST00000395811	hsa-miR-504-5p	17189210	17189216	7mer-m8	17189196	17189217	148.00	-17.89
CAediting_1166564	chr17_17189214_+	ENSG00000133030.18	ENST00000395811	hsa-miR-5699-3p	17189207	17189213	7mer-m8	17189193	17189214	145.00	-16.38
CAediting_1166572	chr17_17189315_+	ENSG00000133030.18	ENST00000395811	hsa-miR-1247-3p	17189309	17189315	7mer-m8	17189294	17189316	160.00	-27.57
CAediting_1166575	chr17_17189330_+	ENSG00000133030.18	ENST00000395811	hsa-miR-100-5p	17189326	17189332	7mer-m8	17189313	17189333	160.00	-22.54
CAediting_1166575	chr17_17189330_+	ENSG00000133030.18	ENST00000395811	hsa-miR-99a-5p	17189326	17189332	7mer-m8	17189313	17189333	160.00	-21.42
CAediting_1166575	chr17_17189330_+	ENSG00000133030.18	ENST00000395811	hsa-miR-99b-5p	17189326	17189332	7mer-m8	17189310	17189333	155.00	-27.77
CAediting_1166579	chr17_17189391_+	ENSG00000133030.18	ENST00000395811	hsa-miR-433-5p	17189385	17189391	7mer-m8	17189369	17189392	163.00	-28.05

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1166550	chr17_17186612_+	ENSG00000133030.18	ENST00000395811	hsa-miR-1200	17186608	17186614	7mer-m8	17186594	17186615	141	-18.61
CAediting_1166556	chr17_17186684_+	ENSG00000133030.18	ENST00000395811	hsa-miR-143-5p	17186678	17186684	7mer-m8	17186663	17186685	155	-20.05
CAediting_1166559	chr17_17186706_+	ENSG00000133030.18	ENST00000395811	hsa-miR-1915-5p	17186703	17186708	6mer	17186688	17186709	148	-30.67
CAediting_1166574	chr17_17189328_+	ENSG00000133030.18	ENST00000395811	hsa-miR-20b-3p	17189324	17189330	7mer-m8	17189309	17189331	153	-18.18
CAediting_1166575	chr17_17189330_+	ENSG00000133030.18	ENST00000395811	hsa-miR-20b-3p	17189324	17189330	7mer-m8	17189309	17189331	153	-18.18
CAediting_1166556	chr17_17186684_+	ENSG00000133030.18	ENST00000395811	hsa-miR-301b-3p	17186680	17186685	6mer	17186664	17186686	143	-17.82
CAediting_1166581	chr17_17189449_+	ENSG00000133030.18	ENST00000395811	hsa-miR-30b-3p	17189442	17189449	8mer-1a	17189428	17189449	148	-16.89
CAediting_1166555	chr17_17186668_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3136-5p	17186661	17186667	7mer-m8	17186648	17186668	149	-14.06
CAediting_1166566	chr17_17189263_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3174	17189259	17189264	6mer	17189245	17189265	142	-24.12
CAediting_1166569	chr17_17189282_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3689a-3p	17189275	17189281	7mer-m8	17189262	17189282	146	-20.25
CAediting_1166581	chr17_17189449_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3689a-3p	17189442	17189449	8mer-1a	17189427	17189449	150	-23.91
CAediting_1166569	chr17_17189282_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3689b-3p	17189275	17189281	7mer-m8	17189262	17189282	154	-23.63
CAediting_1166581	chr17_17189449_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3689b-3p	17189442	17189449	8mer-1a	17189427	17189449	150	-23.96
CAediting_1166569	chr17_17189282_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3689c	17189275	17189281	7mer-m8	17189262	17189282	154	-23.63
CAediting_1166581	chr17_17189449_+	ENSG00000133030.18	ENST00000395811	hsa-miR-3689c	17189442	17189449	8mer-1a	17189427	17189449	150	-23.96
CAediting_1166567	chr17_17189268_+	ENSG00000133030.18	ENST00000395811	hsa-miR-377-5p	17189266	17189272	7mer-m8	17189250	17189273	150	-19.6
CAediting_1166568	chr17_17189269_+	ENSG00000133030.18	ENST00000395811	hsa-miR-377-5p	17189266	17189272	7mer-m8	17189250	17189273	150	-19.6
CAediting_1166580	chr17_17189400_+	ENSG00000133030.18	ENST00000395811	hsa-miR-378a-5p	17189396	17189402	7mer-m8	17189380	17189403	145	-16.27
CAediting_1166554	chr17_17186639_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4437	17186636	17186642	7mer-m8	17186623	17186643	146	-19.53
CAediting_1166555	chr17_17186668_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4439	17186661	17186667	7mer-m8	17186644	17186668	148	-20.91
CAediting_1166571	chr17_17189306_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4478	17189303	17189309	7mer-m8	17189295	17189310	149	-25.05
CAediting_1166563	chr17_17189212_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4522	17189210	17189216	7mer-m8	17189196	17189217	152	-15.11
CAediting_1166564	chr17_17189214_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4522	17189210	17189216	7mer-m8	17189196	17189217	152	-15.11
CAediting_1166561	chr17_17189207_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4635	17189203	17189209	7mer-1a	17189189	17189209	142	-13.66
CAediting_1166565	chr17_17189232_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4638-3p	17189226	17189232	7mer-m8	17189213	17189233	145	-21.33
CAediting_1166571	chr17_17189306_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4649-3p	17189300	17189306	7mer-m8	17189287	17189307	140	-14.11
CAediting_1166551	chr17_17186621_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4777-3p	17186618	17186624	7mer-m8	17186600	17186625	154	-17.97
CAediting_1166552	chr17_17186625_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4777-3p	17186618	17186624	7mer-m8	17186600	17186625	154	-17.97
CAediting_1166569	chr17_17189282_+	ENSG00000133030.18	ENST00000395811	hsa-miR-490-3p	17189279	17189285	7mer-m8	17189264	17189286	146	-17.33
CAediting_1166570	chr17_17189293_+	ENSG00000133030.18	ENST00000395811	hsa-miR-5197-5p	17189288	17189294	7mer-m8	17189273	17189295	150	-10.45
CAediting_1166546	chr17_17186592_+	ENSG00000133030.18	ENST00000395811	hsa-miR-5690	17186589	17186595	7mer-m8	17186575	17186596	150	-13.72
CAediting_1166573	chr17_17189318_+	ENSG00000133030.18	ENST00000395811	hsa-miR-5690	17189315	17189321	7mer-m8	17189302	17189322	145	-16.75
CAediting_1166567	chr17_17189268_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6086	17189266	17189272	7mer-m8	17189254	17189273	150	-21.06
CAediting_1166568	chr17_17189269_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6086	17189266	17189272	7mer-m8	17189254	17189273	150	-21.06
CAediting_1166548	chr17_17186604_+	ENSG00000133030.18	ENST00000395811	hsa-miR-619-5p	17186599	17186604	6mer	17186584	17186605	154	-28.66
CAediting_1166567	chr17_17189268_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6516-5p	17189262	17189268	7mer-m8	17189247	17189269	146	-13.83
CAediting_1166568	chr17_17189269_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6516-5p	17189262	17189268	7mer-m8	17189247	17189269	146	-13.83
CAediting_1166571	chr17_17189306_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6765-5p	17189300	17189305	6mer	17189285	17189306	147	-25.76
CAediting_1166569	chr17_17189282_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6779-5p	17189275	17189281	7mer-m8	17189264	17189282	152	-23.44
CAediting_1166581	chr17_17189449_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6779-5p	17189442	17189449	8mer-1a	17189431	17189449	144	-23.53
CAediting_1166569	chr17_17189282_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6780a-5p	17189275	17189281	7mer-m8	17189258	17189282	147	-24.53
CAediting_1166569	chr17_17189282_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6852-5p	17189278	17189283	6mer	17189264	17189284	140	-22.29
CAediting_1166562	chr17_17189210_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6888-3p	17189207	17189213	7mer-m8	17189194	17189214	147	-10.01
CAediting_1166563	chr17_17189212_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6888-3p	17189207	17189213	7mer-m8	17189194	17189214	147	-10.01
CAediting_1166564	chr17_17189214_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6888-3p	17189207	17189213	7mer-m8	17189194	17189214	147	-10.01
CAediting_1166571	chr17_17189306_+	ENSG00000133030.18	ENST00000395811	hsa-miR-7160-5p	17189301	17189307	7mer-m8	17189289	17189308	149	-18.69
CAediting_1166579	chr17_17189391_+	ENSG00000133030.18	ENST00000395811	hsa-miR-7855-5p	17189385	17189390	6mer	17189371	17189391	140	-24.29
CAediting_1166581	chr17_17189449_+	ENSG00000133030.18	ENST00000395811	hsa-miR-887-5p	17189443	17189450	8mer-1a	17189429	17189450	150	-17.21
CAediting_1166582	chr17_17189450_+	ENSG00000133030.18	ENST00000395811	hsa-miR-887-5p	17189443	17189450	8mer-1a	17189429	17189450	150	-17.21

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_748296	chr10_51299626_+	ENSG00000133030.18	ENST00000395811	hsa-miR-605-3p	17188214	17188220	7mer-m8	17188200	17188221	140	-15.25
CAediting_748296	chr10_51299626_+	ENSG00000133030.18	ENST00000395811	hsa-miR-605-3p	17190020	17190026	7mer-m8	17190007	17190027	141	-17.45
CAediting_980496	chr14_31014685_-	ENSG00000133030.18	ENST00000395811	hsa-miR-624-3p	17185232	17185238	7mer-m8	17185220	17185239	152	-13.9
CAediting_980496	chr14_31014685_-	ENSG00000133030.18	ENST00000395811	hsa-miR-624-3p	17188825	17188831	7mer-m8	17188809	17188832	144	-22.33
CAediting_980496	chr14_31014685_-	ENSG00000133030.18	ENST00000395811	hsa-miR-624-3p	17190572	17190578	7mer-m8	17190559	17190579	153	-16.96
CAediting_980496	chr14_31014685_-	ENSG00000133030.18	ENST00000395811	hsa-miR-624-3p	17191137	17191143	7mer-1a	17191122	17191143	148	-16.27
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000395811	hsa-miR-200b-3p	17185937	17185943	7mer-m8	17185923	17185944	155	-15.45
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000395811	hsa-miR-200b-3p	17187906	17187912	7mer-m8	17187892	17187913	140	-9.67
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000395811	hsa-miR-200b-3p	17188138	17188144	7mer-m8	17188124	17188145	140	-13.16
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000395811	hsa-miR-200b-3p	17190027	17190033	7mer-m8	17190013	17190034	147	-11.29
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000395811	hsa-miR-200b-3p	17185424	17185430	7mer-m8	17185409	17185431	149	-15.81
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000395811	hsa-miR-200b-3p	17191035	17191042	8mer-1a	17191021	17191042	145	-15.83
CAediting_980496	chr14_31014685_-	ENSG00000133030.18	ENST00000341712	hsa-miR-624-3p	17185232	17185238	7mer-m8	17185220	17185239	152	-13.9
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000341712	hsa-miR-200b-3p	17185424	17185430	7mer-m8	17185409	17185431	149	-15.81
CAediting_980496	chr14_31014685_-	ENSG00000133030.18	ENST00000584067	hsa-miR-624-3p	17185232	17185238	7mer-m8	17185220	17185239	152	-13.9
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000584067	hsa-miR-200b-3p	17185424	17185430	7mer-m8	17185409	17185431	149	-15.81
CAediting_980496	chr14_31014685_-	ENSG00000133030.18	ENST00000313485	hsa-miR-624-3p	17185232	17185238	7mer-m8	17185220	17185239	152	-13.9
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000313485	hsa-miR-200b-3p	17185424	17185430	7mer-m8	17185409	17185431	149	-15.81
CAediting_980496	chr14_31014685_-	ENSG00000133030.18	ENST00000414263	hsa-miR-624-3p	17185232	17185238	7mer-m8	17185220	17185239	152	-13.9
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000414263	hsa-miR-200b-3p	17185424	17185430	7mer-m8	17185409	17185431	149	-15.81
CAediting_980496	chr14_31014685_-	ENSG00000133030.18	ENST00000579361	hsa-miR-624-3p	17185232	17185238	7mer-m8	17185220	17185239	152	-13.9
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000579361	hsa-miR-200b-3p	17185424	17185430	7mer-m8	17185409	17185431	149	-15.81
CAediting_86358	chr1_109598906_+	ENSG00000133030.18	ENST00000395806	hsa-miR-197-5p	17057749	17057754	6mer	17057749	17057774	142	-39.8
CAediting_1054808	chr15_66496985_-	ENSG00000133030.18	ENST00000395811	hsa-miR-4512	17188408	17188415	8mer-1a	17188393	17188415	148	-19.81
CAediting_1229413	chr17_67471544_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548aa	17187010	17187016	7mer-m8	17186993	17187017	140	-11.62
CAediting_1229414	chr17_67471546_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548aa	17185629	17185635	7mer-m8	17185612	17185636	156	-18.55
CAediting_1368054	chr19_46709310_-	ENSG00000133030.18	ENST00000395811	hsa-miR-320e	17188470	17188476	7mer-m8	17188458	17188477	143	-16.22
CAediting_1368054	chr19_46709310_-	ENSG00000133030.18	ENST00000395811	hsa-miR-320e	17188495	17188502	8mer-1a	17188482	17188502	145	-20.08
CAediting_86358	chr1_109598906_+	ENSG00000133030.18	ENST00000395811	hsa-miR-197-5p	17188099	17188106	8mer-1a	17188084	17188106	156	-20.67
CAediting_1399425	chr20_1392958_-	ENSG00000133030.18	ENST00000395811	hsa-miR-6869-5p	17189979	17189985	7mer-m8	17189965	17189986	140	-17.66
CAediting_396018	chr5_1062918_-	ENSG00000133030.18	ENST00000395811	hsa-miR-4635	17185280	17185286	7mer-m8	17185267	17185287	141	-13.38
CAediting_580943	chr7_100356700_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6840-3p	17188169	17188175	7mer-m8	17188155	17188176	156	-27.47
CAediting_396018	chr5_1062918_-	ENSG00000133030.18	ENST00000341712	hsa-miR-4635	17185280	17185286	7mer-m8	17185267	17185287	141	-13.38
CAediting_396018	chr5_1062918_-	ENSG00000133030.18	ENST00000584067	hsa-miR-4635	17185280	17185286	7mer-m8	17185267	17185287	141	-13.38
CAediting_396018	chr5_1062918_-	ENSG00000133030.18	ENST00000313485	hsa-miR-4635	17185280	17185286	7mer-m8	17185267	17185287	141	-13.38
CAediting_396018	chr5_1062918_-	ENSG00000133030.18	ENST00000414263	hsa-miR-4635	17185280	17185286	7mer-m8	17185267	17185287	141	-13.38
CAediting_396018	chr5_1062918_-	ENSG00000133030.18	ENST00000579361	hsa-miR-4635	17185280	17185286	7mer-m8	17185267	17185287	141	-13.38
CAediting_1524209	chrX_134546392_-	ENSG00000133030.18	ENST00000395806	hsa-miR-503-5p	17057754	17057760	7mer-m8	17057739	17057761	152	-22.95
CAediting_1524209	chrX_134546392_-	ENSG00000133030.18	ENST00000395811	hsa-miR-503-5p	17187033	17187038	6mer	17187017	17187039	144	-20.77
CAediting_1524209	chrX_134546392_-	ENSG00000133030.18	ENST00000395811	hsa-miR-503-5p	17188211	17188217	7mer-m8	17188197	17188218	149	-20.22

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_86358	chr1_109598906_+	ENSG00000133030.18	ENST00000395811	hsa-miR-197-5p	17189978	17189985	8mer-1a	17189963	17189985	142	-14.37
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000395811	hsa-miR-200b-3p	17185199	17185206	8mer-1a	17185185	17185206	150	-11.1
CAediting_1306324	chr19_13836464_-	ENSG00000133030.18	ENST00000395811	hsa-miR-27a-3p	17189512	17189518	7mer-m8	17189499	17189519	140	-9.46
CAediting_1306324	chr19_13836464_-	ENSG00000133030.18	ENST00000395811	hsa-miR-27a-3p	17190601	17190607	7mer-m8	17190589	17190608	141	-13.47
CAediting_1368054	chr19_46709310_-	ENSG00000133030.18	ENST00000395811	hsa-miR-320e	17187865	17187871	7mer-m8	17187855	17187872	145	-17.58
CAediting_1368054	chr19_46709310_-	ENSG00000133030.18	ENST00000395811	hsa-miR-320e	17184927	17184933	7mer-m8	17184917	17184934	145	-20.25
CAediting_1368054	chr19_46709310_-	ENSG00000133030.18	ENST00000395811	hsa-miR-320e	17185332	17185338	7mer-m8	17185322	17185339	148	-14.09
CAediting_688080	chr9_63819626_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4477b	17191201	17191207	7mer-m8	17191188	17191208	152	-14.21
CAediting_688081	chr9_63819627_+	ENSG00000133030.18	ENST00000395811	hsa-miR-4477b	17191201	17191207	7mer-m8	17191188	17191208	152	-14.21
CAediting_396018	chr5_1062918_-	ENSG00000133030.18	ENST00000395811	hsa-miR-4635	17189203	17189209	7mer-1a	17189189	17189209	142	-13.66
CAediting_396018	chr5_1062918_-	ENSG00000133030.18	ENST00000395811	hsa-miR-4635	17190609	17190615	7mer-m8	17190595	17190616	148	-12.87
CAediting_1524209	chrX_134546392_-	ENSG00000133030.18	ENST00000395811	hsa-miR-503-5p	17184952	17184958	7mer-m8	17184935	17184959	144	-19.92
CAediting_1229413	chr17_67471544_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548aa	17186182	17186188	7mer-m8	17186167	17186189	152	-18.27
CAediting_1229414	chr17_67471546_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548aa	17186182	17186188	7mer-m8	17186167	17186189	152	-18.27
CAediting_1229415	chr17_67471547_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548aa	17186182	17186188	7mer-m8	17186167	17186189	152	-18.27
CAediting_1229413	chr17_67471544_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548aa	17191101	17191108	8mer-1a	17191083	17191108	145	-10.14
CAediting_1229414	chr17_67471546_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548aa	17191101	17191108	8mer-1a	17191083	17191108	145	-10.14
CAediting_1229415	chr17_67471547_+	ENSG00000133030.18	ENST00000395811	hsa-miR-548aa	17191101	17191108	8mer-1a	17191083	17191108	145	-10.14
CAediting_748296	chr10_51299626_+	ENSG00000133030.18	ENST00000395811	hsa-miR-605-3p	17187137	17187144	8mer-1a	17187124	17187144	148	-13.85
CAediting_748296	chr10_51299626_+	ENSG00000133030.18	ENST00000395811	hsa-miR-605-3p	17188362	17188368	7mer-m8	17188348	17188369	144	-13.16
CAediting_748296	chr10_51299626_+	ENSG00000133030.18	ENST00000395811	hsa-miR-605-3p	17185401	17185407	7mer-m8	17185389	17185408	144	-11.73
CAediting_980496	chr14_31014685_-	ENSG00000133030.18	ENST00000395811	hsa-miR-624-3p	17188041	17188047	7mer-m8	17188029	17188048	149	-20.25
CAediting_580943	chr7_100356700_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6840-3p	17188745	17188752	8mer-1a	17188732	17188752	145	-21.92
CAediting_580943	chr7_100356700_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6840-3p	17189658	17189665	8mer-1a	17189644	17189665	141	-18.9
CAediting_580943	chr7_100356700_+	ENSG00000133030.18	ENST00000395811	hsa-miR-6840-3p	17190007	17190013	7mer-m8	17189993	17190014	148	-28.83
CAediting_1399425	chr20_1392958_-	ENSG00000133030.18	ENST00000395811	hsa-miR-6869-5p	17189005	17189011	7mer-m8	17188991	17189012	148	-18.33
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000341712	hsa-miR-200b-3p	17185199	17185206	8mer-1a	17185185	17185206	150	-11.1
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000584067	hsa-miR-200b-3p	17185199	17185206	8mer-1a	17185185	17185206	150	-11.1
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000313485	hsa-miR-200b-3p	17185199	17185206	8mer-1a	17185185	17185206	150	-11.1
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000414263	hsa-miR-200b-3p	17185199	17185206	8mer-1a	17185185	17185206	150	-11.1
CAediting_393	chr1_1167164_+	ENSG00000133030.18	ENST00000579361	hsa-miR-200b-3p	17185199	17185206	8mer-1a	17185185	17185206	150	-11.1

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for MPRIP

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for MPRIP

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BRCA	CAediting_1166547	chr17_17186598_+	0.000124015093099615	0.16077251221044	.	.	.	.
OV	CAediting_1166547	chr17_17186598_+	0.0234106331775185	0.179148102749379	.	.	.	.
SKCM	CAediting_1166547	chr17_17186598_+	5.16517434904501e-05	0.304413671816055	.	.	.	.
TGCT	CAediting_1166547	chr17_17186598_+	2.09355241845201e-05	0.501413136408777	.	.	.	.
BRCA	CAediting_1166550	chr17_17186612_+	0.0334956650181543	0.0895433484265966	.	.	.	.
SKCM	CAediting_1166550	chr17_17186612_+	1.31648069126523e-05	0.31190814033528	.	.	.	.
SARC	CAediting_1166550	chr17_17186612_+	0.00177042022588244	0.293490985521471	0.013337396624644	0.234255394464562	.	.
TGCT	CAediting_1166550	chr17_17186612_+	0.00231480792884556	0.358406644740432	.	.	.	.

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Relation with cancer stages for MPRIP

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
KIRP	clinical_stage	CAediting_1166550	chr17_17186612_+	0.00974770700251251	0.377271648689776
KIRP	pathologic_stage	CAediting_1166550	chr17_17186612_+	0.00815097867648445	0.311662637515879
LUSC	pathologic_stage	CAediting_1166550	chr17_17186612_+	0.0323490664588148	0.182303629553434
TGCT	pathologic_stage	CAediting_1166550	chr17_17186612_+	0.0220451240641151	-0.380544419323095

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Relation with survival for MPRIP

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
KIRC	CAediting_1166550	chr17_17186612_+	0.00626489656825524	0.0060229	0.0271002
ESCA	CAediting_1166550	chr17_17186612_+	0.00536906326371056	0.0440608	0.00196769
SARC	CAediting_1166550	chr17_17186612_+	0.0124016044718362	0.0244089	181.4

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RelatedDrugs for MPRIP

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for MPRIP

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
MPRIP	C0043094	Weight Gain	1	CTD_human
MPRIP	C3495676	Anorectal Malformations	1	GENOMICS_ENGLAND

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene