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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: ANKLE2 (CAeditome ID:23141)

Gene summary for ANKLE2

check button Gene summary
Gene informationGene symbol

ANKLE2

Gene ID

23141

Gene nameankyrin repeat and LEM domain containing 2
SynonymsKIAA0692|LEMD7|Lem4|MCPH16
Cytomap

12q24.33

Type of geneprotein-coding
Descriptionankyrin repeat and LEM domain-containing protein 2LEM domain containing 7LEM domain-containing protein 4
Modification date20210518
UniProtAcc

Q86XL3

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
ANKLE2

GO:0051721

Ankyrin repeat and LEM domain-containing protein 2

22770216

ANKLE2

GO:0007417

Ankyrin repeat and LEM domain-containing protein 2

25259927

ANKLE2

GO:0035307

Ankyrin repeat and LEM domain-containing protein 2

22770216

ANKLE2

GO:0042326

Ankyrin repeat and LEM domain-containing protein 2

22770216

ANKLE2

GO:0043066

Ankyrin repeat and LEM domain-containing protein 2

25259927

ANKLE2

GO:0030176

Ankyrin repeat and LEM domain-containing protein 2

22770216


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RNA A-to-I events for ANKLE2

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000176915.13

check button RNA A-to-I editing events in Cancer.
CAediting_949092(132725820, -), CAediting_949093(132730630, -), CAediting_949094(132730657, -), CAediting_949095(132730680, -), CAediting_949096(132730698, -), CAediting_949097(132730715, -), CAediting_949098(132730812, -), CAediting_949099(132731666, -), CAediting_949100(132731676, -), CAediting_949101(132731682, -), CAediting_949102(132731699, -), CAediting_949103(132731709, -), CAediting_949104(132731721, -), CAediting_949105(132731729, -), CAediting_949106(132734047, -), CAediting_949107(132734051, -), CAediting_949108(132736155, -), CAediting_949109(132736224, -), CAediting_949110(132737449, -), CAediting_949111(132737458, -), CAediting_949112(132737464, -), CAediting_949113(132737470, -), CAediting_949114(132737471, -), CAediting_949115(132737480, -), CAediting_949116(132737489, -), CAediting_949117(132737498, -), CAediting_949118(132737503, -), CAediting_949119(132737532, -), CAediting_949120(132737535, -), CAediting_949121(132737552, -), CAediting_949122(132737567, -), CAediting_949123(132737583, -), CAediting_949124(132737587, -), CAediting_949125(132737591, -), CAediting_949126(132737603, -), CAediting_949127(132737606, -), CAediting_949128(132737615, -), CAediting_949129(132737632, -), CAediting_949130(132737639, -), CAediting_949131(132737668, -), CAediting_949132(132737701, -), CAediting_949133(132737709, -), CAediting_949134(132737713, -), CAediting_949135(132737749, -), CAediting_949136(132737788, -), CAediting_949137(132737853, -), CAediting_949138(132737864, -), CAediting_949139(132737871, -), CAediting_949140(132737877, -), CAediting_949141(132737879, -), CAediting_949142(132737880, -), CAediting_949143(132737884, -), CAediting_949144(132737888, -), CAediting_949145(132737902, -), CAediting_949146(132737923, -), CAediting_949147(132737924, -), CAediting_949148(132737925, -), CAediting_949149(132737926, -), CAediting_949150(132737930, -), CAediting_949151(132737931, -), CAediting_949152(132737932, -), CAediting_949153(132737933, -), CAediting_949154(132737955, -), CAediting_949155(132737967, -), CAediting_949156(132737970, -), CAediting_949157(132737978, -), CAediting_949158(132737985, -), CAediting_949159(132737991, -), CAediting_949160(132738026, -), CAediting_949161(132738027, -), CAediting_949162(132738033, -), CAediting_949163(132738045, -), CAediting_949164(132738585, -), CAediting_949165(132738590, -), CAediting_949166(132738592, -), CAediting_949167(132738597, -), CAediting_949168(132738622, -), CAediting_949169(132738636, -), CAediting_949170(132738653, -), CAediting_949171(132738657, -), CAediting_949172(132738663, -), CAediting_949173(132738669, -), CAediting_949174(132738685, -), CAediting_949175(132738689, -), CAediting_949176(132738719, -), CAediting_949177(132738720, -), CAediting_949178(132738729, -), CAediting_949179(132738791, -), CAediting_949180(132738797, -), CAediting_949181(132748956, -), CAediting_949182(132751313, -), CAediting_949183(132751513, -), CAediting_949184(132751514, -), CAediting_949185(132751810, -), CAediting_949186(132752224, -), CAediting_949187(132753244, -), CAediting_949188(132753819, -), CAediting_949189(132755299, -), CAediting_949190(132755301, -), CAediting_949191(132755378, -), CAediting_949192(132755381, -), CAediting_949193(132755738, -), CAediting_949194(132755740, -), CAediting_949195(132755807, -), CAediting_949196(132755984, -), CAediting_949197(132756010, -), CAediting_949198(132756013, -), CAediting_949199(132756094, -), CAediting_949200(132756112, -), CAediting_949201(132756248, -), CAediting_949202(132756344, -), CAediting_949203(132756364, -), CAediting_949204(132756365, -), CAediting_949205(132756526, -), CAediting_949206(132756662, -), CAediting_949207(132756669, -), CAediting_949208(132756683, -), CAediting_949209(132756684, -), CAediting_949210(132756698, -), CAediting_949211(132756721, -), CAediting_949212(132756743, -), CAediting_949213(132756760, -), CAediting_949214(132756807, -), CAediting_949215(132756819, -), CAediting_949216(132756822, -), CAediting_949217(132757618, -), CAediting_949218(132757655, -), CAediting_949219(132757658, -), CAediting_949220(132757701, -), CAediting_949221(132757711, -), CAediting_949222(132757872, -), CAediting_949223(132757908, -), CAediting_949224(132757916, -), CAediting_949225(132758153, -), CAediting_949226(132758207, -), CAediting_949227(132758298, -), CAediting_949228(132758310, -), CAediting_949229(132758314, -), CAediting_949230(132758326, -), CAediting_949231(132758346, -), CAediting_949232(132758377, -), CAediting_949233(132758553, -), CAediting_949234(132758629, -), CAediting_949235(132758661, -), CAediting_949236(132758662, -), CAediting_949237(132758672, -), CAediting_949238(132758690, -), CAediting_949239(132758726, -), CAediting_949240(132758742, -), CAediting_949241(132758750, -), CAediting_949242(132758793, -),

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RNA editing positional annotations for ANKLE2 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_949092chr12_132725820_-ncRNA_exonic
CAediting_949093chr12_132730630_-ncRNA_intronic
CAediting_949094chr12_132730657_-ncRNA_intronic
CAediting_949095chr12_132730680_-ncRNA_intronic
CAediting_949096chr12_132730698_-ncRNA_intronic
CAediting_949097chr12_132730715_-ncRNA_intronic
CAediting_949098chr12_132730812_-ncRNA_intronic
CAediting_949099chr12_132731666_-ncRNA_intronic
CAediting_949100chr12_132731676_-ncRNA_intronic
CAediting_949101chr12_132731682_-ncRNA_intronic
CAediting_949102chr12_132731699_-ncRNA_intronic
CAediting_949103chr12_132731709_-ncRNA_intronic
CAediting_949104chr12_132731721_-ncRNA_intronic
CAediting_949105chr12_132731729_-ncRNA_intronic
CAediting_949106chr12_132734047_-ncRNA_exonic
CAediting_949107chr12_132734051_-ncRNA_exonic
CAediting_949108chr12_132736155_-ncRNA_intronic
CAediting_949109chr12_132736224_-ncRNA_intronic
CAediting_949110chr12_132737449_-ncRNA_exonic
CAediting_949111chr12_132737458_-ncRNA_exonic
CAediting_949112chr12_132737464_-ncRNA_exonic
CAediting_949113chr12_132737470_-ncRNA_exonic
CAediting_949114chr12_132737471_-ncRNA_exonic
CAediting_949115chr12_132737480_-ncRNA_exonic
CAediting_949116chr12_132737489_-ncRNA_exonic
CAediting_949117chr12_132737498_-ncRNA_exonic
CAediting_949118chr12_132737503_-ncRNA_exonic
CAediting_949119chr12_132737532_-ncRNA_exonic
CAediting_949120chr12_132737535_-ncRNA_exonic
CAediting_949121chr12_132737552_-ncRNA_exonic
CAediting_949122chr12_132737567_-ncRNA_exonic
CAediting_949123chr12_132737583_-ncRNA_exonic
CAediting_949124chr12_132737587_-ncRNA_exonic
CAediting_949125chr12_132737591_-ncRNA_exonic
CAediting_949126chr12_132737603_-ncRNA_exonic
CAediting_949127chr12_132737606_-ncRNA_exonic
CAediting_949128chr12_132737615_-ncRNA_exonic
CAediting_949129chr12_132737632_-ncRNA_exonic
CAediting_949130chr12_132737639_-ncRNA_exonic
CAediting_949131chr12_132737668_-ncRNA_exonic
CAediting_949132chr12_132737701_-ncRNA_exonic
CAediting_949133chr12_132737709_-ncRNA_exonic
CAediting_949134chr12_132737713_-ncRNA_exonic
CAediting_949135chr12_132737749_-ncRNA_exonic
CAediting_949136chr12_132737788_-ncRNA_exonic
CAediting_949137chr12_132737853_-ncRNA_exonic
CAediting_949138chr12_132737864_-ncRNA_exonic
CAediting_949139chr12_132737871_-ncRNA_exonic
CAediting_949140chr12_132737877_-ncRNA_exonic
CAediting_949141chr12_132737879_-ncRNA_exonic
CAediting_949142chr12_132737880_-ncRNA_exonic
CAediting_949143chr12_132737884_-ncRNA_exonic
CAediting_949144chr12_132737888_-ncRNA_exonic
CAediting_949145chr12_132737902_-ncRNA_exonic
CAediting_949146chr12_132737923_-ncRNA_exonic
CAediting_949147chr12_132737924_-ncRNA_exonic
CAediting_949148chr12_132737925_-ncRNA_exonic
CAediting_949149chr12_132737926_-ncRNA_exonic
CAediting_949150chr12_132737930_-ncRNA_exonic
CAediting_949151chr12_132737931_-ncRNA_exonic
CAediting_949152chr12_132737932_-ncRNA_exonic
CAediting_949153chr12_132737933_-ncRNA_exonic
CAediting_949154chr12_132737955_-ncRNA_exonic
CAediting_949155chr12_132737967_-ncRNA_exonic
CAediting_949156chr12_132737970_-ncRNA_exonic
CAediting_949157chr12_132737978_-ncRNA_exonic
CAediting_949158chr12_132737985_-ncRNA_exonic
CAediting_949159chr12_132737991_-ncRNA_exonic
CAediting_949160chr12_132738026_-ncRNA_exonic
CAediting_949161chr12_132738027_-ncRNA_exonic
CAediting_949162chr12_132738033_-ncRNA_exonic
CAediting_949163chr12_132738045_-ncRNA_exonic
CAediting_949164chr12_132738585_-ncRNA_exonic
CAediting_949165chr12_132738590_-ncRNA_exonic
CAediting_949166chr12_132738592_-ncRNA_exonic
CAediting_949167chr12_132738597_-ncRNA_exonic
CAediting_949168chr12_132738622_-ncRNA_exonic
CAediting_949169chr12_132738636_-ncRNA_exonic
CAediting_949170chr12_132738653_-ncRNA_exonic
CAediting_949171chr12_132738657_-ncRNA_exonic
CAediting_949172chr12_132738663_-ncRNA_exonic
CAediting_949173chr12_132738669_-ncRNA_exonic
CAediting_949174chr12_132738685_-ncRNA_exonic
CAediting_949175chr12_132738689_-ncRNA_exonic
CAediting_949176chr12_132738719_-ncRNA_exonic
CAediting_949177chr12_132738720_-ncRNA_exonic
CAediting_949178chr12_132738729_-ncRNA_exonic
CAediting_949179chr12_132738791_-ncRNA_exonic
CAediting_949180chr12_132738797_-ncRNA_exonic
CAediting_949181chr12_132748956_-ncRNA_exonic
CAediting_949182chr12_132751313_-ncRNA_exonic
CAediting_949183chr12_132751513_-ncRNA_intronic
CAediting_949184chr12_132751514_-ncRNA_intronic
CAediting_949185chr12_132751810_-ncRNA_intronic
CAediting_949186chr12_132752224_-ncRNA_intronic
CAediting_949187chr12_132753244_-ncRNA_intronic
CAediting_949188chr12_132753819_-ncRNA_intronic
CAediting_949189chr12_132755299_-ncRNA_exonic
CAediting_949190chr12_132755301_-ncRNA_exonic
CAediting_949191chr12_132755378_-ncRNA_exonic
CAediting_949192chr12_132755381_-ncRNA_exonic
CAediting_949193chr12_132755738_-ncRNA_exonic
CAediting_949194chr12_132755740_-ncRNA_exonic
CAediting_949195chr12_132755807_-ncRNA_exonic
CAediting_949196chr12_132755984_-ncRNA_exonic
CAediting_949197chr12_132756010_-ncRNA_exonic
CAediting_949198chr12_132756013_-ncRNA_exonic
CAediting_949199chr12_132756094_-ncRNA_exonic
CAediting_949200chr12_132756112_-ncRNA_exonic
CAediting_949201chr12_132756248_-ncRNA_exonic
CAediting_949202chr12_132756344_-ncRNA_exonic
CAediting_949203chr12_132756364_-ncRNA_exonic
CAediting_949204chr12_132756365_-ncRNA_exonic
CAediting_949205chr12_132756526_-ncRNA_exonic
CAediting_949206chr12_132756662_-ncRNA_exonic
CAediting_949207chr12_132756669_-ncRNA_exonic
CAediting_949208chr12_132756683_-ncRNA_exonic
CAediting_949209chr12_132756684_-ncRNA_exonic
CAediting_949210chr12_132756698_-ncRNA_exonic
CAediting_949211chr12_132756721_-ncRNA_exonic
CAediting_949212chr12_132756743_-ncRNA_exonic
CAediting_949213chr12_132756760_-ncRNA_exonic
CAediting_949214chr12_132756807_-ncRNA_exonic
CAediting_949215chr12_132756819_-ncRNA_exonic
CAediting_949216chr12_132756822_-ncRNA_exonic
CAediting_949217chr12_132757618_-ncRNA_exonic
CAediting_949218chr12_132757655_-ncRNA_exonic
CAediting_949219chr12_132757658_-ncRNA_exonic
CAediting_949220chr12_132757701_-ncRNA_exonic
CAediting_949221chr12_132757711_-ncRNA_exonic
CAediting_949222chr12_132757872_-ncRNA_exonic
CAediting_949223chr12_132757908_-ncRNA_exonic
CAediting_949224chr12_132757916_-ncRNA_exonic
CAediting_949225chr12_132758153_-ncRNA_exonic
CAediting_949226chr12_132758207_-ncRNA_exonic
CAediting_949227chr12_132758298_-ncRNA_exonic
CAediting_949228chr12_132758310_-ncRNA_exonic
CAediting_949229chr12_132758314_-ncRNA_exonic
CAediting_949230chr12_132758326_-ncRNA_exonic
CAediting_949231chr12_132758346_-ncRNA_exonic
CAediting_949232chr12_132758377_-ncRNA_exonic
CAediting_949233chr12_132758553_-ncRNA_exonic
CAediting_949234chr12_132758629_-ncRNA_exonic
CAediting_949235chr12_132758661_-ncRNA_exonic
CAediting_949236chr12_132758662_-ncRNA_exonic
CAediting_949237chr12_132758672_-ncRNA_exonic
CAediting_949238chr12_132758690_-ncRNA_exonic
CAediting_949239chr12_132758726_-ncRNA_exonic
CAediting_949240chr12_132758742_-ncRNA_exonic
CAediting_949241chr12_132758750_-ncRNA_exonic
CAediting_949242chr12_132758793_-ncRNA_exonic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_949093chr12_132730630_-SINEAluAluJo
CAediting_949094chr12_132730657_-SINEAluAluJo
CAediting_949095chr12_132730680_-SINEAluAluJo
CAediting_949096chr12_132730698_-SINEAluAluJo
CAediting_949097chr12_132730715_-SINEAluAluJo
CAediting_949098chr12_132730812_-SINEAluAluJo
CAediting_949099chr12_132731666_-SINEAluAluSz
CAediting_949100chr12_132731676_-SINEAluAluSz
CAediting_949101chr12_132731682_-SINEAluAluSz
CAediting_949102chr12_132731699_-SINEAluAluSz
CAediting_949103chr12_132731709_-SINEAluAluSz
CAediting_949104chr12_132731721_-SINEAluAluSz
CAediting_949105chr12_132731729_-SINEAluAluSz
CAediting_949106chr12_132734047_-SINEAluAluSx4
CAediting_949107chr12_132734051_-SINEAluAluSx4
CAediting_949108chr12_132736155_-SINEAluAluY
CAediting_949109chr12_132736224_-SINEAluAluY
CAediting_949110chr12_132737449_-SINEAluAluSx1
CAediting_949111chr12_132737458_-SINEAluAluSx1
CAediting_949112chr12_132737464_-SINEAluAluSx1
CAediting_949113chr12_132737470_-SINEAluAluSx1
CAediting_949114chr12_132737471_-SINEAluAluSx1
CAediting_949115chr12_132737480_-SINEAluAluSx1
CAediting_949116chr12_132737489_-SINEAluAluSx1
CAediting_949117chr12_132737498_-SINEAluAluSx1
CAediting_949118chr12_132737503_-SINEAluAluSx1
CAediting_949119chr12_132737532_-SINEAluAluSx1
CAediting_949120chr12_132737535_-SINEAluAluSx1
CAediting_949121chr12_132737552_-SINEAluAluSx1
CAediting_949122chr12_132737567_-SINEAluAluSx1
CAediting_949123chr12_132737583_-SINEAluAluSx1
CAediting_949124chr12_132737587_-SINEAluAluSx1
CAediting_949125chr12_132737591_-SINEAluAluSx1
CAediting_949126chr12_132737603_-SINEAluAluSx1
CAediting_949127chr12_132737606_-SINEAluAluSx1
CAediting_949128chr12_132737615_-SINEAluAluSx1
CAediting_949129chr12_132737632_-SINEAluAluSx1
CAediting_949130chr12_132737639_-SINEAluAluSx1
CAediting_949131chr12_132737668_-SINEAluAluSx1
CAediting_949132chr12_132737701_-SINEAluAluSx1
CAediting_949133chr12_132737709_-SINEAluAluSx1
CAediting_949134chr12_132737713_-SINEAluAluSx1
CAediting_949135chr12_132737749_-SINEAluAluJr
CAediting_949136chr12_132737788_-SINEAluAluJr
CAediting_949137chr12_132737853_-SINEAluAluJr
CAediting_949138chr12_132737864_-SINEAluAluJr
CAediting_949139chr12_132737871_-SINEAluAluJr
CAediting_949140chr12_132737877_-SINEAluAluJr
CAediting_949141chr12_132737879_-SINEAluAluJr
CAediting_949142chr12_132737880_-SINEAluAluJr
CAediting_949143chr12_132737884_-SINEAluAluJr
CAediting_949144chr12_132737888_-SINEAluAluJr
CAediting_949145chr12_132737902_-SINEAluAluJr
CAediting_949146chr12_132737923_-SINEAluAluJr
CAediting_949147chr12_132737924_-SINEAluAluJr
CAediting_949148chr12_132737925_-SINEAluAluJr
CAediting_949149chr12_132737926_-SINEAluAluJr
CAediting_949150chr12_132737930_-SINEAluAluJr
CAediting_949151chr12_132737931_-SINEAluAluJr
CAediting_949152chr12_132737932_-SINEAluAluJr
CAediting_949153chr12_132737933_-SINEAluAluJr
CAediting_949154chr12_132737955_-SINEAluAluJr
CAediting_949155chr12_132737967_-SINEAluAluJr
CAediting_949156chr12_132737970_-SINEAluAluJr
CAediting_949157chr12_132737978_-SINEAluAluJr
CAediting_949158chr12_132737985_-SINEAluAluJr
CAediting_949159chr12_132737991_-SINEAluAluJr
CAediting_949160chr12_132738026_-SINEAluAluJr
CAediting_949161chr12_132738027_-SINEAluAluJr
CAediting_949162chr12_132738033_-SINEAluAluJr
CAediting_949163chr12_132738045_-SINEAluAluJr
CAediting_949164chr12_132738585_-SINEAluAluY
CAediting_949165chr12_132738590_-SINEAluAluY
CAediting_949166chr12_132738592_-SINEAluAluY
CAediting_949167chr12_132738597_-SINEAluAluY
CAediting_949168chr12_132738622_-SINEAluAluY
CAediting_949169chr12_132738636_-SINEAluAluY
CAediting_949170chr12_132738653_-SINEAluAluY
CAediting_949171chr12_132738657_-SINEAluAluY
CAediting_949172chr12_132738663_-SINEAluAluY
CAediting_949173chr12_132738669_-SINEAluAluY
CAediting_949174chr12_132738685_-SINEAluAluY
CAediting_949175chr12_132738689_-SINEAluAluY
CAediting_949176chr12_132738719_-SINEAluAluY
CAediting_949177chr12_132738720_-SINEAluAluY
CAediting_949178chr12_132738729_-SINEAluAluY
CAediting_949179chr12_132738791_-SINEAluAluY
CAediting_949180chr12_132738797_-SINEAluAluY
CAediting_949181chr12_132748956_-SINEAluAluJr
CAediting_949182chr12_132751313_-SINEAluAluSx1
CAediting_949183chr12_132751513_-SINEAluAluSx1
CAediting_949184chr12_132751514_-SINEAluAluSx1
CAediting_949185chr12_132751810_-SINEAluAluSx1
CAediting_949186chr12_132752224_-SINEAluAluSx
CAediting_949187chr12_132753244_-SINEAluAluJb
CAediting_949188chr12_132753819_-SINEAluAluJb
CAediting_949189chr12_132755299_-SINEAluAluSq
CAediting_949190chr12_132755301_-SINEAluAluSq
CAediting_949191chr12_132755378_-SINEAluAluSq
CAediting_949192chr12_132755381_-SINEAluAluSq
CAediting_949193chr12_132755738_-SINEAluAluSx1
CAediting_949194chr12_132755740_-SINEAluAluSx1
CAediting_949195chr12_132755807_-SINEAluAluSx1
CAediting_949196chr12_132755984_-SINEAluAluSg
CAediting_949197chr12_132756010_-SINEAluAluSg
CAediting_949198chr12_132756013_-SINEAluAluSg
CAediting_949199chr12_132756094_-SINEAluAluSg
CAediting_949200chr12_132756112_-SINEAluAluSg
CAediting_949201chr12_132756248_-SINEAluAluSx
CAediting_949202chr12_132756344_-SINEAluAluSx
CAediting_949203chr12_132756364_-SINEAluAluSx
CAediting_949204chr12_132756365_-SINEAluAluSx
CAediting_949205chr12_132756526_-SINEAluAluJb
CAediting_949206chr12_132756662_-SINEAluAluSg4
CAediting_949207chr12_132756669_-SINEAluAluSg4
CAediting_949208chr12_132756683_-SINEAluAluSg4
CAediting_949209chr12_132756684_-SINEAluAluSg4
CAediting_949210chr12_132756698_-SINEAluAluSg4
CAediting_949211chr12_132756721_-SINEAluAluSg4
CAediting_949212chr12_132756743_-SINEAluAluSg4
CAediting_949213chr12_132756760_-SINEAluAluSg4
CAediting_949214chr12_132756807_-SINEAluAluSg4
CAediting_949215chr12_132756819_-SINEAluAluSg4
CAediting_949216chr12_132756822_-SINEAluAluSg4
CAediting_949217chr12_132757618_-SINEAluAluY
CAediting_949218chr12_132757655_-SINEAluAluY
CAediting_949219chr12_132757658_-SINEAluAluY
CAediting_949220chr12_132757701_-SINEAluAluY
CAediting_949221chr12_132757711_-SINEAluAluY
CAediting_949222chr12_132757872_-SINEAluAluJo
CAediting_949223chr12_132757908_-SINEAluAluJo
CAediting_949224chr12_132757916_-SINEAluAluJo
CAediting_949225chr12_132758153_-SINEAluAluSz
CAediting_949226chr12_132758207_-SINEAluAluSz
CAediting_949227chr12_132758298_-SINEAluAluSz
CAediting_949228chr12_132758310_-SINEAluAluSz
CAediting_949229chr12_132758314_-SINEAluAluSz
CAediting_949230chr12_132758326_-SINEAluAluSz
CAediting_949231chr12_132758346_-SINEAluAluSz
CAediting_949232chr12_132758377_-SINEAluAluSz
CAediting_949233chr12_132758553_-SINEAluAluSx3
CAediting_949234chr12_132758629_-SINEAluAluSx3
CAediting_949235chr12_132758661_-SINEAluAluSx3
CAediting_949236chr12_132758662_-SINEAluAluSx3
CAediting_949237chr12_132758672_-SINEAluAluSx3
CAediting_949238chr12_132758690_-SINEAluAluSx3
CAediting_949239chr12_132758726_-SINEAluAluSx3
CAediting_949240chr12_132758742_-SINEAluAluSx3
CAediting_949241chr12_132758750_-SINEAluAluSx3
CAediting_949242chr12_132758793_-SINEAluAluSx3

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RNA A-to-I editing events in the alternative splicing sites for ANKLE2

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
IRCAediting_949146chr12_132737923_-132737923:1327379315SS0+6iAAGTAAAAA-8.31AAGTAAAAG-7.62
IRCAediting_949147chr12_132737924_-132737923:1327379315SS0+5iAAGTAAAAA-8.31AAGTAAAGA-6.12
IRCAediting_949148chr12_132737925_-132737923:1327379315SS0+4iAAGTAAAAA-8.31AAGTAAGAA-10.36
IRCAediting_949149chr12_132737926_-132737923:1327379315SS0+3iAAGTAAAAA-8.31AAGTAGAAA-12.18
IRCAediting_949150chr12_132737930_-132737923:1327379315SS2+0iAAGTAAAAA-8.31AGGTAAAAA-12.18
IRCAediting_949151chr12_132737931_-132737923:1327379315SS3+0iAAGTAAAAA-8.31GAGTAAAAA-9.38
ESCAediting_949213chr12_132756760_-132756756:1327567783SS0+2iTTGTATTTTTTTTTTAGTAGAGA4.48TTGTATTTTTTTTTTAGTGGAGA-3.47
ESCAediting_949213chr12_132756760_-132756759:1327567813SS2+0iTTTTTGTATTTTTTTTTTAGTAG7.09TTTTTGTATTTTTTTTTTAGTGG8.41
IRCAediting_949213chr12_132756760_-132756756:1327567783SS0+2iTTGTATTTTTTTTTTAGTAGAGA4.48TTGTATTTTTTTTTTAGTGGAGA-3.47
IRCAediting_949213chr12_132756760_-132756759:1327567813SS2+0iTTTTTGTATTTTTTTTTTAGTAG7.09TTTTTGTATTTTTTTTTTAGTGG8.41

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000176915.13.ANKLE2.
boxplot

check button Correlation between RNA A-to-I editing and PSI for ENSG00000176915.13.ANKLE2.
boxplot

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ANKLE2

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for ANKLE2

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ANKLE2

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_949092chr12_132725820_-ENSG00000176915.13ENST00000357997hsa-miR-47731327258151327258228mer-1a132725815132725836142.00-9.93
CAediting_949092chr12_132725820_-ENSG00000176915.13ENST00000357997hsa-miR-47731327258151327258228mer-1a132725815132725836142.00-9.93

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_980496chr14_31014685_-ENSG00000176915.13ENST00000357997hsa-miR-624-3p1327269131327269197mer-1a132726902132726920149-14.71
CAediting_980496chr14_31014685_-ENSG00000176915.13ENST00000357997hsa-miR-624-3p1327269021327269098mer-1a132726902132726920149-14.71
CAediting_980496chr14_31014685_-ENSG00000176915.13ENST00000542282hsa-miR-624-3p1327269131327269197mer-1a132726902132726920149-14.71
CAediting_980496chr14_31014685_-ENSG00000176915.13ENST00000542282hsa-miR-624-3p1327269021327269098mer-1a132726902132726920149-14.71
CAediting_1229413chr17_67471544_+ENSG00000176915.13ENST00000357997hsa-miR-548aa1327262991327263057mer-m8132726298132726322147-15.18
CAediting_580943chr7_100356700_+ENSG00000176915.13ENST00000357997hsa-miR-6840-3p1327255501327255567mer-m8132725549132725567148-25.68
CAediting_604450chr7_133034877_-ENSG00000176915.13ENST00000535036hsa-miR-36541327368971327369037mer-m8132736896132736914140-19.7

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1160181chr17_7017644_-ENSG00000176915.13ENST00000357997hsa-miR-195-3p1327259231327259297mer-m8132725922132725943149-18.16
CAediting_580943chr7_100356700_+ENSG00000176915.13ENST00000357997hsa-miR-6840-3p1327261841327261907mer-m8132726183132726204140-17.08
CAediting_580943chr7_100356700_+ENSG00000176915.13ENST00000357997hsa-miR-6840-3p1327267811327267877mer-m8132726780132726799141-27.28

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ANKLE2

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ANKLE2

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
OVCAediting_949115chr12_132737480_-0.02907855788029110.30581852256167....
CESCCAediting_949137chr12_132737853_-....0.02870720116198830.28495031828175

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Relation with cancer stages for ANKLE2

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
ESCApathologic_stageCAediting_949137chr12_132737853_-0.04722209682652690.266359505675434

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Relation with survival for ANKLE2

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for ANKLE2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ANKLE2

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
ANKLE2C3711387Autosomal Recessive Primary Microcephaly1ORPHANET
ANKLE2C4225249MICROCEPHALY 16, PRIMARY, AUTOSOMAL RECESSIVE1CTD_human;GENOMICS_ENGLAND;UNIPROT