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Editing gene: SIRT2 (CAeditome ID:22933)

Gene summary for SIRT2

Gene summary

Gene information	Gene symbol	SIRT2
	Gene ID	22933
	Gene name	sirtuin 2
	Synonyms	SIR2\|SIR2L\|SIR2L2
	Cytomap	19q13.2
	Type of gene	protein-coding
	Description	NAD-dependent protein deacetylase sirtuin-2NAD-dependent deacetylase sirtuin-2SIR2-like protein 2regulatory protein SIR2 homolog 2silent information regulator 2sir2-related protein type 2sirtuin type 2
	Modification date	20210518
	UniProtAcc	Q8IXJ6
	Context	- 34068624(Targeting SIRT2 Sensitizes Melanoma Cells to Cisplatin via an EGFR-Dependent Mechanism)

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
SIRT2	GO:0003682	NAD-dependent protein deacetylase sirtuin-2	23908241
SIRT2	GO:0003950	NAD-dependent protein deacetylase sirtuin-2	10381378
SIRT2	GO:0004407	NAD-dependent protein deacetylase sirtuin-2	17488717
SIRT2	GO:0008270	NAD-dependent protein deacetylase sirtuin-2	11427894
SIRT2	GO:0017136	NAD-dependent protein deacetylase sirtuin-2	11427894
SIRT2	GO:0017136	NAD-dependent protein deacetylase sirtuin-2	12697818
SIRT2	GO:0033558	NAD-dependent protein deacetylase sirtuin-2	17172643
SIRT2	GO:0033558	NAD-dependent protein deacetylase sirtuin-2	20543840
SIRT2	GO:0034979	NAD-dependent protein deacetylase sirtuin-2	18722353
SIRT2	GO:0034979	NAD-dependent protein deacetylase sirtuin-2	21949390
SIRT2	GO:0034979	NAD-dependent protein deacetylase sirtuin-2	23932781
SIRT2	GO:0042903	NAD-dependent protein deacetylase sirtuin-2	12620231
SIRT2	GO:0042903	NAD-dependent protein deacetylase sirtuin-2	18722353
SIRT2	GO:0042903	NAD-dependent protein deacetylase sirtuin-2	23886946
SIRT2	GO:0043130	NAD-dependent protein deacetylase sirtuin-2	12697818
SIRT2	GO:0046970	NAD-dependent protein deacetylase sirtuin-2	16648462
SIRT2	GO:0070403	NAD-dependent protein deacetylase sirtuin-2	11427894
SIRT2	GO:0000122	NAD-dependent protein deacetylase sirtuin-2	18722353
SIRT2	GO:0006471	NAD-dependent protein deacetylase sirtuin-2	10381378
SIRT2	GO:0006476	NAD-dependent protein deacetylase sirtuin-2	17172643
SIRT2	GO:0006476	NAD-dependent protein deacetylase sirtuin-2	20543840
SIRT2	GO:0006476	NAD-dependent protein deacetylase sirtuin-2	21949390
SIRT2	GO:0034983	NAD-dependent protein deacetylase sirtuin-2	23932781
SIRT2	GO:0035729	NAD-dependent protein deacetylase sirtuin-2	23908241
SIRT2	GO:0045843	NAD-dependent protein deacetylase sirtuin-2	12887892
SIRT2	GO:0045892	NAD-dependent protein deacetylase sirtuin-2	12887892
SIRT2	GO:0048012	NAD-dependent protein deacetylase sirtuin-2	23908241
SIRT2	GO:0070933	NAD-dependent protein deacetylase sirtuin-2	16648462
SIRT2	GO:0070933	NAD-dependent protein deacetylase sirtuin-2	17488717
SIRT2	GO:0071219	NAD-dependent protein deacetylase sirtuin-2	23908241
SIRT2	GO:0071456	NAD-dependent protein deacetylase sirtuin-2	24681946
SIRT2	GO:0090042	NAD-dependent protein deacetylase sirtuin-2	18722353
SIRT2	GO:0090042	NAD-dependent protein deacetylase sirtuin-2	23886946
SIRT2	GO:0005634	NAD-dependent protein deacetylase sirtuin-2	15213244
SIRT2	GO:0005634	NAD-dependent protein deacetylase sirtuin-2	16648462
SIRT2	GO:0005634	NAD-dependent protein deacetylase sirtuin-2	17726514
SIRT2	GO:0005634	NAD-dependent protein deacetylase sirtuin-2	23908241
SIRT2	GO:0005694	NAD-dependent protein deacetylase sirtuin-2	16648462
SIRT2	GO:0005730	NAD-dependent protein deacetylase sirtuin-2	0000052
SIRT2	GO:0005737	NAD-dependent protein deacetylase sirtuin-2	12697818
SIRT2	GO:0005737	NAD-dependent protein deacetylase sirtuin-2	15213244
SIRT2	GO:0005737	NAD-dependent protein deacetylase sirtuin-2	16079181
SIRT2	GO:0005737	NAD-dependent protein deacetylase sirtuin-2	16648462
SIRT2	GO:0005737	NAD-dependent protein deacetylase sirtuin-2	17726514
SIRT2	GO:0005737	NAD-dependent protein deacetylase sirtuin-2	20543840
SIRT2	GO:0005737	NAD-dependent protein deacetylase sirtuin-2	23908241
SIRT2	GO:0005813	NAD-dependent protein deacetylase sirtuin-2	17488717
SIRT2	GO:0005813	NAD-dependent protein deacetylase sirtuin-2	17726514
SIRT2	GO:0005814	NAD-dependent protein deacetylase sirtuin-2	17726514
SIRT2	GO:0005819	NAD-dependent protein deacetylase sirtuin-2	17726514
SIRT2	GO:0005829	NAD-dependent protein deacetylase sirtuin-2	0000052
SIRT2	GO:0005829	NAD-dependent protein deacetylase sirtuin-2	24681946
SIRT2	GO:0005874	NAD-dependent protein deacetylase sirtuin-2	12620231
SIRT2	GO:0005886	NAD-dependent protein deacetylase sirtuin-2	0000052
SIRT2	GO:0030496	NAD-dependent protein deacetylase sirtuin-2	17726514
SIRT2	GO:0072686	NAD-dependent protein deacetylase sirtuin-2	17488717

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RNA A-to-I events for SIRT2

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000068903.18

RNA A-to-I editing events in Cancer.

CAediting_1348492(38879915, -), CAediting_1348493(38879918, -), CAediting_1348494(38879922, -), CAediting_1348495(38879928, -), CAediting_1348496(38879931, -), CAediting_1348497(38879963, -), CAediting_1348498(38880075, -), CAediting_1348499(38880089, -), CAediting_1348500(38880113, -), CAediting_1348501(38881761, -), CAediting_1348502(38881766, -), CAediting_1348503(38881790, -), CAediting_1348504(38881870, -), CAediting_1348505(38881889, -), CAediting_1348506(38882031, -), CAediting_1348507(38882090, -), CAediting_1348508(38882114, -), CAediting_1348509(38882163, -), CAediting_1348510(38882195, -), CAediting_1348511(38882203, -), CAediting_1348512(38882214, -), CAediting_1348513(38884018, -), CAediting_1348514(38884067, -), CAediting_1348515(38884742, -), CAediting_1348516(38884946, -), CAediting_1348517(38884972, -), CAediting_1348518(38884994, -), CAediting_1348519(38885004, -), CAediting_1348520(38885178, -), CAediting_1348521(38885377, -), CAediting_1348522(38887062, -), CAediting_1348523(38890474, -), CAediting_1348524(38890646, -), CAediting_1348525(38890651, -), CAediting_1348526(38892139, -), CAediting_1348527(38892671, -), CAediting_1348528(38892698, -), CAediting_1348529(38894095, -), CAediting_1348530(38894106, -), CAediting_1348531(38894107, -), CAediting_1348532(38894130, -), CAediting_1348533(38894132, -), CAediting_1348534(38894134, -), CAediting_1348535(38894135, -), CAediting_1348536(38894154, -), CAediting_1348537(38894157, -), CAediting_1348538(38894170, -), CAediting_1348539(38894194, -), CAediting_1348540(38894205, -), CAediting_1348541(38894212, -), CAediting_1348542(38894218, -), CAediting_1348543(38894229, -), CAediting_1348544(38894245, -), CAediting_1348545(38894261, -), CAediting_1348546(38894266, -), CAediting_1348547(38894267, -), CAediting_1348548(38894268, -), CAediting_1348549(38894306, -), CAediting_1348550(38894309, -), CAediting_1348551(38894311, -), CAediting_1348552(38894326, -), CAediting_1348553(38894328, -), CAediting_1348554(38894337, -), CAediting_1348555(38894342, -), CAediting_1348556(38894356, -), CAediting_1348557(38894377, -), CAediting_1348558(38894382, -), CAediting_1348559(38894383, -), CAediting_1348560(38894391, -), CAediting_1348561(38894399, -), CAediting_1348562(38894405, -), CAediting_1348563(38895664, -), CAediting_1348564(38895678, -), CAediting_1348565(38895680, -), CAediting_1348566(38895692, -), CAediting_1348567(38895693, -), CAediting_1348568(38895702, -), CAediting_1348569(38895715, -), CAediting_1348570(38895716, -), CAediting_1348571(38895719, -), CAediting_1348572(38895720, -), CAediting_1348573(38895723, -), CAediting_1348574(38895732, -), CAediting_1348575(38895745, -), CAediting_1348576(38895757, -), CAediting_1348577(38895763, -), CAediting_1348578(38895771, -), CAediting_1348579(38895814, -), CAediting_1348580(38895816, -), CAediting_1348581(38895828, -), CAediting_1348582(38895838, -), CAediting_1348583(38895843, -), CAediting_1348584(38895937, -), CAediting_1348585(38895944, -), CAediting_1348586(38895948, -), CAediting_1348587(38895950, -), CAediting_1348588(38895960, -), CAediting_1348589(38895989, -), CAediting_1348590(38895990, -), CAediting_1348591(38895996, -), CAediting_1348592(38896009, -), CAediting_1348593(38896010, -), CAediting_1348594(38896049, -), CAediting_1348595(38896446, -), CAediting_1348596(38896485, -), CAediting_1348597(38896486, -), CAediting_1348598(38896494, -), CAediting_1348599(38897529, -), CAediting_1348600(38897530, -), CAediting_1348601(38897551, -), CAediting_1348602(38897552, -), CAediting_1348603(38897553, -), CAediting_1348604(38897556, -), CAediting_1348605(38897575, -), CAediting_1348606(38897620, -), CAediting_1348607(38897621, -), CAediting_1348608(38897649, -), CAediting_1348609(38897657, -), CAediting_1348610(38897663, -), CAediting_1348611(38897671, -), CAediting_1348612(38897689, -), CAediting_1348613(38897692, -), CAediting_1348614(38897693, -), CAediting_1348615(38897695, -), CAediting_1348616(38897696, -), CAediting_1348617(38897700, -), CAediting_1348618(38897725, -), CAediting_1348619(38897729, -), CAediting_1348620(38897742, -), CAediting_1348621(38897744, -), CAediting_1348622(38897750, -), CAediting_1348623(38897772, -), CAediting_1348624(38897793, -), CAediting_1348625(38897798, -), CAediting_1348626(38897807, -), CAediting_1348627(38897815, -), CAediting_1348628(38897821, -), CAediting_1348629(38897827, -), CAediting_1348630(38897839, -), CAediting_1348631(38897868, -), CAediting_1348632(38897869, -), CAediting_1348633(38897874, -), CAediting_1348634(38897931, -), CAediting_1348635(38897976, -), CAediting_1348636(38897977, -), CAediting_1348637(38898007, -), CAediting_1348638(38898736, -), CAediting_1348639(38899618, -),

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RNA editing positional annotations for SIRT2 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1348492	chr19_38879915_-	ncRNA_exonic
CAediting_1348493	chr19_38879918_-	ncRNA_exonic
CAediting_1348494	chr19_38879922_-	ncRNA_exonic
CAediting_1348495	chr19_38879928_-	ncRNA_exonic
CAediting_1348496	chr19_38879931_-	ncRNA_exonic
CAediting_1348497	chr19_38879963_-	ncRNA_exonic
CAediting_1348498	chr19_38880075_-	ncRNA_exonic
CAediting_1348499	chr19_38880089_-	ncRNA_exonic
CAediting_1348500	chr19_38880113_-	ncRNA_exonic
CAediting_1348501	chr19_38881761_-	ncRNA_intronic
CAediting_1348502	chr19_38881766_-	ncRNA_intronic
CAediting_1348503	chr19_38881790_-	ncRNA_intronic
CAediting_1348504	chr19_38881870_-	ncRNA_intronic
CAediting_1348505	chr19_38881889_-	ncRNA_intronic
CAediting_1348506	chr19_38882031_-	ncRNA_intronic
CAediting_1348507	chr19_38882090_-	ncRNA_intronic
CAediting_1348508	chr19_38882114_-	ncRNA_intronic
CAediting_1348509	chr19_38882163_-	ncRNA_intronic
CAediting_1348510	chr19_38882195_-	ncRNA_intronic
CAediting_1348511	chr19_38882203_-	ncRNA_intronic
CAediting_1348512	chr19_38882214_-	ncRNA_intronic
CAediting_1348513	chr19_38884018_-	ncRNA_intronic
CAediting_1348514	chr19_38884067_-	ncRNA_intronic
CAediting_1348515	chr19_38884742_-	ncRNA_intronic
CAediting_1348516	chr19_38884946_-	ncRNA_intronic
CAediting_1348517	chr19_38884972_-	ncRNA_intronic
CAediting_1348518	chr19_38884994_-	ncRNA_intronic
CAediting_1348519	chr19_38885004_-	ncRNA_intronic
CAediting_1348520	chr19_38885178_-	ncRNA_intronic
CAediting_1348521	chr19_38885377_-	ncRNA_intronic
CAediting_1348522	chr19_38887062_-	ncRNA_intronic
CAediting_1348523	chr19_38890474_-	ncRNA_intronic
CAediting_1348524	chr19_38890646_-	ncRNA_intronic
CAediting_1348525	chr19_38890651_-	ncRNA_intronic
CAediting_1348526	chr19_38892139_-	ncRNA_intronic
CAediting_1348527	chr19_38892671_-	ncRNA_intronic
CAediting_1348528	chr19_38892698_-	ncRNA_intronic
CAediting_1348529	chr19_38894095_-	ncRNA_exonic
CAediting_1348530	chr19_38894106_-	ncRNA_exonic
CAediting_1348531	chr19_38894107_-	ncRNA_exonic
CAediting_1348532	chr19_38894130_-	ncRNA_exonic
CAediting_1348533	chr19_38894132_-	ncRNA_exonic
CAediting_1348534	chr19_38894134_-	ncRNA_exonic
CAediting_1348535	chr19_38894135_-	ncRNA_exonic
CAediting_1348536	chr19_38894154_-	ncRNA_exonic
CAediting_1348537	chr19_38894157_-	ncRNA_exonic
CAediting_1348538	chr19_38894170_-	ncRNA_exonic
CAediting_1348539	chr19_38894194_-	ncRNA_exonic
CAediting_1348540	chr19_38894205_-	ncRNA_exonic
CAediting_1348541	chr19_38894212_-	ncRNA_exonic
CAediting_1348542	chr19_38894218_-	ncRNA_exonic
CAediting_1348543	chr19_38894229_-	ncRNA_exonic
CAediting_1348544	chr19_38894245_-	ncRNA_exonic
CAediting_1348545	chr19_38894261_-	ncRNA_exonic
CAediting_1348546	chr19_38894266_-	ncRNA_exonic
CAediting_1348547	chr19_38894267_-	ncRNA_exonic
CAediting_1348548	chr19_38894268_-	ncRNA_exonic
CAediting_1348549	chr19_38894306_-	ncRNA_exonic
CAediting_1348550	chr19_38894309_-	ncRNA_exonic
CAediting_1348551	chr19_38894311_-	ncRNA_exonic
CAediting_1348552	chr19_38894326_-	ncRNA_exonic
CAediting_1348553	chr19_38894328_-	ncRNA_exonic
CAediting_1348554	chr19_38894337_-	ncRNA_exonic
CAediting_1348555	chr19_38894342_-	ncRNA_exonic
CAediting_1348556	chr19_38894356_-	ncRNA_exonic
CAediting_1348557	chr19_38894377_-	ncRNA_exonic
CAediting_1348558	chr19_38894382_-	ncRNA_exonic
CAediting_1348559	chr19_38894383_-	ncRNA_exonic
CAediting_1348560	chr19_38894391_-	ncRNA_exonic
CAediting_1348561	chr19_38894399_-	ncRNA_exonic
CAediting_1348562	chr19_38894405_-	ncRNA_exonic
CAediting_1348563	chr19_38895664_-	ncRNA_intronic
CAediting_1348564	chr19_38895678_-	ncRNA_intronic
CAediting_1348565	chr19_38895680_-	ncRNA_intronic
CAediting_1348566	chr19_38895692_-	ncRNA_intronic
CAediting_1348567	chr19_38895693_-	ncRNA_intronic
CAediting_1348568	chr19_38895702_-	ncRNA_intronic
CAediting_1348569	chr19_38895715_-	ncRNA_intronic
CAediting_1348570	chr19_38895716_-	ncRNA_intronic
CAediting_1348571	chr19_38895719_-	ncRNA_intronic
CAediting_1348572	chr19_38895720_-	ncRNA_intronic
CAediting_1348573	chr19_38895723_-	ncRNA_intronic
CAediting_1348574	chr19_38895732_-	ncRNA_intronic
CAediting_1348575	chr19_38895745_-	ncRNA_intronic
CAediting_1348576	chr19_38895757_-	ncRNA_intronic
CAediting_1348577	chr19_38895763_-	ncRNA_intronic
CAediting_1348578	chr19_38895771_-	ncRNA_intronic
CAediting_1348579	chr19_38895814_-	ncRNA_intronic
CAediting_1348580	chr19_38895816_-	ncRNA_intronic
CAediting_1348581	chr19_38895828_-	ncRNA_intronic
CAediting_1348582	chr19_38895838_-	ncRNA_intronic
CAediting_1348583	chr19_38895843_-	ncRNA_intronic
CAediting_1348584	chr19_38895937_-	ncRNA_intronic
CAediting_1348585	chr19_38895944_-	ncRNA_intronic
CAediting_1348586	chr19_38895948_-	ncRNA_intronic
CAediting_1348587	chr19_38895950_-	ncRNA_intronic
CAediting_1348588	chr19_38895960_-	ncRNA_intronic
CAediting_1348589	chr19_38895989_-	ncRNA_intronic
CAediting_1348590	chr19_38895990_-	ncRNA_intronic
CAediting_1348591	chr19_38895996_-	ncRNA_intronic
CAediting_1348592	chr19_38896009_-	ncRNA_intronic
CAediting_1348593	chr19_38896010_-	ncRNA_intronic
CAediting_1348594	chr19_38896049_-	ncRNA_intronic
CAediting_1348595	chr19_38896446_-	ncRNA_intronic
CAediting_1348596	chr19_38896485_-	ncRNA_intronic
CAediting_1348597	chr19_38896486_-	ncRNA_intronic
CAediting_1348598	chr19_38896494_-	ncRNA_intronic
CAediting_1348599	chr19_38897529_-	ncRNA_intronic
CAediting_1348600	chr19_38897530_-	ncRNA_intronic
CAediting_1348601	chr19_38897551_-	ncRNA_intronic
CAediting_1348602	chr19_38897552_-	ncRNA_intronic
CAediting_1348603	chr19_38897553_-	ncRNA_intronic
CAediting_1348604	chr19_38897556_-	ncRNA_intronic
CAediting_1348605	chr19_38897575_-	ncRNA_intronic
CAediting_1348606	chr19_38897620_-	ncRNA_intronic
CAediting_1348607	chr19_38897621_-	ncRNA_intronic
CAediting_1348608	chr19_38897649_-	ncRNA_intronic
CAediting_1348609	chr19_38897657_-	ncRNA_intronic
CAediting_1348610	chr19_38897663_-	ncRNA_intronic
CAediting_1348611	chr19_38897671_-	ncRNA_intronic
CAediting_1348612	chr19_38897689_-	ncRNA_intronic
CAediting_1348613	chr19_38897692_-	ncRNA_intronic
CAediting_1348614	chr19_38897693_-	ncRNA_intronic
CAediting_1348615	chr19_38897695_-	ncRNA_intronic
CAediting_1348616	chr19_38897696_-	ncRNA_intronic
CAediting_1348617	chr19_38897700_-	ncRNA_intronic
CAediting_1348618	chr19_38897725_-	ncRNA_intronic
CAediting_1348619	chr19_38897729_-	ncRNA_intronic
CAediting_1348620	chr19_38897742_-	ncRNA_intronic
CAediting_1348621	chr19_38897744_-	ncRNA_intronic
CAediting_1348622	chr19_38897750_-	ncRNA_intronic
CAediting_1348623	chr19_38897772_-	ncRNA_intronic
CAediting_1348624	chr19_38897793_-	ncRNA_intronic
CAediting_1348625	chr19_38897798_-	ncRNA_intronic
CAediting_1348626	chr19_38897807_-	ncRNA_intronic
CAediting_1348627	chr19_38897815_-	ncRNA_intronic
CAediting_1348628	chr19_38897821_-	ncRNA_intronic
CAediting_1348629	chr19_38897827_-	ncRNA_intronic
CAediting_1348630	chr19_38897839_-	ncRNA_intronic
CAediting_1348631	chr19_38897868_-	ncRNA_intronic
CAediting_1348632	chr19_38897869_-	ncRNA_intronic
CAediting_1348633	chr19_38897874_-	ncRNA_intronic
CAediting_1348634	chr19_38897931_-	ncRNA_intronic
CAediting_1348635	chr19_38897976_-	ncRNA_intronic
CAediting_1348636	chr19_38897977_-	ncRNA_intronic
CAediting_1348637	chr19_38898007_-	ncRNA_intronic
CAediting_1348638	chr19_38898736_-	ncRNA_exonic
CAediting_1348639	chr19_38899618_-	UTR5

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1348492	chr19_38879915_-	SINE	Alu	AluSq2
CAediting_1348493	chr19_38879918_-	SINE	Alu	AluSq2
CAediting_1348494	chr19_38879922_-	SINE	Alu	AluSq2
CAediting_1348495	chr19_38879928_-	SINE	Alu	AluSq2
CAediting_1348496	chr19_38879931_-	SINE	Alu	AluSq2
CAediting_1348497	chr19_38879963_-	SINE	Alu	AluSq2
CAediting_1348498	chr19_38880075_-	SINE	Alu	AluSq2
CAediting_1348499	chr19_38880089_-	SINE	Alu	AluSq2
CAediting_1348500	chr19_38880113_-	SINE	Alu	AluSq2
CAediting_1348501	chr19_38881761_-	SINE	Alu	AluJb
CAediting_1348502	chr19_38881766_-	SINE	Alu	AluJb
CAediting_1348503	chr19_38881790_-	SINE	Alu	AluJb
CAediting_1348504	chr19_38881870_-	SINE	Alu	AluJb
CAediting_1348505	chr19_38881889_-	SINE	Alu	AluJb
CAediting_1348506	chr19_38882031_-	SINE	Alu	AluJo
CAediting_1348507	chr19_38882090_-	SINE	Alu	AluJo
CAediting_1348508	chr19_38882114_-	SINE	Alu	AluJo
CAediting_1348509	chr19_38882163_-	SINE	Alu	AluJo
CAediting_1348510	chr19_38882195_-	SINE	Alu	AluJo
CAediting_1348511	chr19_38882203_-	SINE	Alu	AluJo
CAediting_1348512	chr19_38882214_-	SINE	Alu	AluJo
CAediting_1348513	chr19_38884018_-	SINE	Alu	AluJr4
CAediting_1348514	chr19_38884067_-	SINE	Alu	AluJr4
CAediting_1348515	chr19_38884742_-	SINE	Alu	AluSg
CAediting_1348516	chr19_38884946_-	SINE	Alu	AluJr
CAediting_1348517	chr19_38884972_-	SINE	Alu	AluJr
CAediting_1348518	chr19_38884994_-	SINE	Alu	AluJr
CAediting_1348520	chr19_38885178_-	SINE	Alu	AluJo
CAediting_1348521	chr19_38885377_-	SINE	Alu	AluJo
CAediting_1348522	chr19_38887062_-	SINE	Alu	AluSc8
CAediting_1348523	chr19_38890474_-	SINE	Alu	AluSx
CAediting_1348524	chr19_38890646_-	SINE	Alu	AluSx
CAediting_1348525	chr19_38890651_-	SINE	Alu	AluSx
CAediting_1348526	chr19_38892139_-	SINE	Alu	AluSx
CAediting_1348527	chr19_38892671_-	SINE	Alu	AluJr
CAediting_1348528	chr19_38892698_-	SINE	Alu	AluJr
CAediting_1348529	chr19_38894095_-	SINE	Alu	AluJo
CAediting_1348530	chr19_38894106_-	SINE	Alu	AluJo
CAediting_1348531	chr19_38894107_-	SINE	Alu	AluJo
CAediting_1348532	chr19_38894130_-	SINE	Alu	AluJo
CAediting_1348533	chr19_38894132_-	SINE	Alu	AluJo
CAediting_1348534	chr19_38894134_-	SINE	Alu	AluJo
CAediting_1348535	chr19_38894135_-	SINE	Alu	AluJo
CAediting_1348536	chr19_38894154_-	SINE	Alu	AluJo
CAediting_1348537	chr19_38894157_-	SINE	Alu	AluJo
CAediting_1348538	chr19_38894170_-	SINE	Alu	AluJo
CAediting_1348539	chr19_38894194_-	SINE	Alu	AluJo
CAediting_1348540	chr19_38894205_-	SINE	Alu	AluJo
CAediting_1348541	chr19_38894212_-	SINE	Alu	AluJo
CAediting_1348542	chr19_38894218_-	SINE	Alu	AluJo
CAediting_1348543	chr19_38894229_-	SINE	Alu	AluJo
CAediting_1348544	chr19_38894245_-	SINE	Alu	AluJo
CAediting_1348545	chr19_38894261_-	SINE	Alu	AluJo
CAediting_1348546	chr19_38894266_-	SINE	Alu	AluJo
CAediting_1348547	chr19_38894267_-	SINE	Alu	AluJo
CAediting_1348548	chr19_38894268_-	SINE	Alu	AluJo
CAediting_1348549	chr19_38894306_-	SINE	Alu	AluJo
CAediting_1348550	chr19_38894309_-	SINE	Alu	AluJo
CAediting_1348551	chr19_38894311_-	SINE	Alu	AluJo
CAediting_1348552	chr19_38894326_-	SINE	Alu	AluJo
CAediting_1348553	chr19_38894328_-	SINE	Alu	AluJo
CAediting_1348554	chr19_38894337_-	SINE	Alu	AluJo
CAediting_1348555	chr19_38894342_-	SINE	Alu	AluJo
CAediting_1348556	chr19_38894356_-	SINE	Alu	AluJo
CAediting_1348557	chr19_38894377_-	SINE	Alu	AluJo
CAediting_1348558	chr19_38894382_-	SINE	Alu	AluJo
CAediting_1348559	chr19_38894383_-	SINE	Alu	AluJo
CAediting_1348560	chr19_38894391_-	SINE	Alu	AluJo
CAediting_1348561	chr19_38894399_-	SINE	Alu	AluJo
CAediting_1348562	chr19_38894405_-	SINE	Alu	AluJo
CAediting_1348563	chr19_38895664_-	SINE	Alu	AluJr4
CAediting_1348564	chr19_38895678_-	SINE	Alu	AluJr4
CAediting_1348565	chr19_38895680_-	SINE	Alu	AluJr4
CAediting_1348566	chr19_38895692_-	SINE	Alu	AluJr4
CAediting_1348567	chr19_38895693_-	SINE	Alu	AluJr4
CAediting_1348568	chr19_38895702_-	SINE	Alu	AluJr4
CAediting_1348569	chr19_38895715_-	SINE	Alu	AluJr4
CAediting_1348570	chr19_38895716_-	SINE	Alu	AluJr4
CAediting_1348571	chr19_38895719_-	SINE	Alu	AluJr4
CAediting_1348572	chr19_38895720_-	SINE	Alu	AluJr4
CAediting_1348573	chr19_38895723_-	SINE	Alu	AluJr4
CAediting_1348574	chr19_38895732_-	SINE	Alu	AluJr4
CAediting_1348575	chr19_38895745_-	SINE	Alu	AluJr4
CAediting_1348576	chr19_38895757_-	SINE	Alu	AluJr4
CAediting_1348577	chr19_38895763_-	SINE	Alu	AluJr4
CAediting_1348578	chr19_38895771_-	SINE	Alu	AluJr4
CAediting_1348579	chr19_38895814_-	SINE	Alu	AluSc8
CAediting_1348580	chr19_38895816_-	SINE	Alu	AluSc8
CAediting_1348581	chr19_38895828_-	SINE	Alu	AluSc8
CAediting_1348582	chr19_38895838_-	SINE	Alu	AluSc8
CAediting_1348583	chr19_38895843_-	SINE	Alu	AluSc8
CAediting_1348584	chr19_38895937_-	SINE	Alu	AluSc8
CAediting_1348585	chr19_38895944_-	SINE	Alu	AluSc8
CAediting_1348586	chr19_38895948_-	SINE	Alu	AluSc8
CAediting_1348587	chr19_38895950_-	SINE	Alu	AluSc8
CAediting_1348588	chr19_38895960_-	SINE	Alu	AluSc8
CAediting_1348589	chr19_38895989_-	SINE	Alu	AluSc8
CAediting_1348590	chr19_38895990_-	SINE	Alu	AluSc8
CAediting_1348591	chr19_38895996_-	SINE	Alu	AluSc8
CAediting_1348592	chr19_38896009_-	SINE	Alu	AluSc8
CAediting_1348593	chr19_38896010_-	SINE	Alu	AluSc8
CAediting_1348594	chr19_38896049_-	SINE	Alu	AluSc8
CAediting_1348595	chr19_38896446_-	SINE	Alu	FLAM_C
CAediting_1348596	chr19_38896485_-	SINE	Alu	FLAM_C
CAediting_1348597	chr19_38896486_-	SINE	Alu	FLAM_C
CAediting_1348598	chr19_38896494_-	SINE	Alu	FLAM_C
CAediting_1348599	chr19_38897529_-	SINE	Alu	AluJr
CAediting_1348600	chr19_38897530_-	SINE	Alu	AluJr
CAediting_1348601	chr19_38897551_-	SINE	Alu	AluJr
CAediting_1348602	chr19_38897552_-	SINE	Alu	AluJr
CAediting_1348603	chr19_38897553_-	SINE	Alu	AluJr
CAediting_1348604	chr19_38897556_-	SINE	Alu	AluJr
CAediting_1348605	chr19_38897575_-	SINE	Alu	AluJr
CAediting_1348606	chr19_38897620_-	SINE	Alu	AluJr
CAediting_1348607	chr19_38897621_-	SINE	Alu	AluJr
CAediting_1348608	chr19_38897649_-	SINE	Alu	AluJr
CAediting_1348609	chr19_38897657_-	SINE	Alu	AluJr
CAediting_1348610	chr19_38897663_-	SINE	Alu	AluJr
CAediting_1348611	chr19_38897671_-	SINE	Alu	AluJr
CAediting_1348612	chr19_38897689_-	SINE	Alu	AluJr
CAediting_1348613	chr19_38897692_-	SINE	Alu	AluJr
CAediting_1348614	chr19_38897693_-	SINE	Alu	AluJr
CAediting_1348615	chr19_38897695_-	SINE	Alu	AluJr
CAediting_1348616	chr19_38897696_-	SINE	Alu	AluJr
CAediting_1348617	chr19_38897700_-	SINE	Alu	AluJr
CAediting_1348618	chr19_38897725_-	SINE	Alu	AluJr
CAediting_1348619	chr19_38897729_-	SINE	Alu	AluJr
CAediting_1348620	chr19_38897742_-	SINE	Alu	AluJr
CAediting_1348621	chr19_38897744_-	SINE	Alu	AluJr
CAediting_1348622	chr19_38897750_-	SINE	Alu	AluJr
CAediting_1348623	chr19_38897772_-	SINE	Alu	AluJr
CAediting_1348624	chr19_38897793_-	SINE	Alu	AluJr
CAediting_1348625	chr19_38897798_-	SINE	Alu	AluJr
CAediting_1348626	chr19_38897807_-	SINE	Alu	AluJr
CAediting_1348627	chr19_38897815_-	SINE	Alu	AluJr
CAediting_1348628	chr19_38897821_-	SINE	Alu	AluJr
CAediting_1348630	chr19_38897839_-	SINE	Alu	FRAM
CAediting_1348631	chr19_38897868_-	SINE	Alu	FRAM
CAediting_1348632	chr19_38897869_-	SINE	Alu	FRAM
CAediting_1348633	chr19_38897874_-	SINE	Alu	FRAM
CAediting_1348634	chr19_38897931_-	SINE	Alu	FRAM
CAediting_1348635	chr19_38897976_-	SINE	Alu	FRAM
CAediting_1348636	chr19_38897977_-	SINE	Alu	FRAM
CAediting_1348638	chr19_38898736_-	SINE	Alu	AluJo

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RNA A-to-I editing events in the alternative splicing sites for SIRT2

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000068903.18.SIRT2.

Correlation between RNA A-to-I editing and PSI for ENSG00000068903.18.SIRT2.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SIRT2

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for SIRT2

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for SIRT2

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1399425	chr20_1392958_-	ENSG00000068903.18	ENST00000443898	hsa-miR-6869-5p	38889885	38889891	7mer-m8	38889884	38889905	145	-17.78
CAediting_580943	chr7_100356700_+	ENSG00000068903.18	ENST00000451193	hsa-miR-6840-3p	38890612	38890618	7mer-m8	38890611	38890627	141	-27.37
CAediting_1399425	chr20_1392958_-	ENSG00000068903.18	ENST00000451193	hsa-miR-6869-5p	38889885	38889891	7mer-m8	38889884	38889905	145	-17.78
CAediting_1054808	chr15_66496985_-	ENSG00000068903.18	ENST00000423526	hsa-miR-4512	38891859	38891866	8mer-1a	38891859	38891880	141	-20.7
CAediting_1399425	chr20_1392958_-	ENSG00000068903.18	ENST00000423526	hsa-miR-6869-5p	38889885	38889891	7mer-m8	38889884	38889905	145	-17.78

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_442554	chr5_154685830_+	ENSG00000068903.18	ENST00000358931	hsa-miR-1303	38878972	38878978	7mer-m8	38878971	38878992	140	-15.14
CAediting_442554	chr5_154685830_+	ENSG00000068903.18	ENST00000358931	hsa-miR-1303	38878878	38878884	7mer-m8	38878877	38878900	155	-20.55
CAediting_580943	chr7_100356700_+	ENSG00000068903.18	ENST00000358931	hsa-miR-6840-3p	38878905	38878911	7mer-m8	38878904	38878924	146	-20.7
CAediting_442554	chr5_154685830_+	ENSG00000068903.18	ENST00000392081	hsa-miR-1303	38878972	38878978	7mer-m8	38878971	38878992	140	-15.14
CAediting_442554	chr5_154685830_+	ENSG00000068903.18	ENST00000392081	hsa-miR-1303	38878878	38878884	7mer-m8	38878877	38878900	155	-20.55
CAediting_580943	chr7_100356700_+	ENSG00000068903.18	ENST00000392081	hsa-miR-6840-3p	38878905	38878911	7mer-m8	38878904	38878924	146	-20.7

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for SIRT2

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for SIRT2

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for SIRT2

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for SIRT2

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
STAD	CAediting_1348611	chr19_38897671_-	0.0128850719634607	0.0042095	25.8707

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RelatedDrugs for SIRT2

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for SIRT2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
SIRT2	C0525045	Mood Disorders	1	PSYGENET
SIRT2	C2939186	Disturbance in mood	1	PSYGENET

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene