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Editing gene: ZNF25 (CAeditome ID:219749)

Gene summary for ZNF25

Gene summary

Gene information	Gene symbol	ZNF25
	Gene ID	219749
	Gene name	zinc finger protein 25
	Synonyms	KOX19\|Zfp9
	Cytomap	10p11.21
	Type of gene	protein-coding
	Description	zinc finger protein 25zinc finger protein 25 (KOX 19)zinc finger protein KOX19
	Modification date	20210518
	UniProtAcc	P17030
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for ZNF25

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000175395.14

RNA A-to-I editing events in Cancer.

CAediting_745144(37952730, -), CAediting_745145(37952749, -), CAediting_745146(37955822, -), CAediting_745147(37955947, -), CAediting_745148(37956787, -), CAediting_745149(37956793, -), CAediting_745150(37956839, -), CAediting_745151(37956852, -), CAediting_745152(37956853, -), CAediting_745153(37956858, -), CAediting_745154(37956863, -), CAediting_745155(37958769, -), CAediting_745156(37958791, -), CAediting_745157(37958937, -), CAediting_745158(37958949, -), CAediting_745159(37959005, -), CAediting_745160(37959022, -), CAediting_745161(37959023, -), CAediting_745162(37959047, -), CAediting_745163(37959624, -), CAediting_745164(37959625, -), CAediting_745165(37959675, -), CAediting_745166(37959677, -), CAediting_745167(37959710, -), CAediting_745168(37959779, -), CAediting_745169(37959780, -), CAediting_745170(37960053, -), CAediting_745171(37960055, -), CAediting_745172(37960082, -), CAediting_745173(37960083, -), CAediting_745174(37963171, -), CAediting_745175(37963715, -), CAediting_745176(37963716, -), CAediting_745177(37963730, -), CAediting_745178(37963731, -), CAediting_745179(37963758, -), CAediting_745180(37963809, -), CAediting_745181(37963853, -), CAediting_745182(37963858, -), CAediting_745183(37963863, -), CAediting_745184(37963875, -), CAediting_745185(37963899, -), CAediting_745186(37963961, -), CAediting_745187(37963973, -), CAediting_745188(37964032, -), CAediting_745189(37964048, -), CAediting_745190(37964070, -), CAediting_745191(37964075, -), CAediting_745192(37964076, -), CAediting_745193(37964179, -), CAediting_745194(37964185, -), CAediting_745195(37966305, -), CAediting_745196(37966691, -), CAediting_745197(37967470, -), CAediting_745198(37967482, -), CAediting_745199(37967483, -), CAediting_745200(37967486, -), CAediting_745201(37967508, -), CAediting_745202(37967513, -), CAediting_745203(37967543, -), CAediting_745204(37967549, -), CAediting_745205(37967570, -), CAediting_745206(37967574, -), CAediting_745207(37967577, -), CAediting_745208(37967583, -), CAediting_745209(37967587, -), CAediting_745210(37967625, -), CAediting_745211(37967650, -), CAediting_745212(37967667, -), CAediting_745213(37967674, -), CAediting_745214(37968233, -),

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RNA editing positional annotations for ZNF25 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_745144	chr10_37952730_-	exonic
CAediting_745145	chr10_37952749_-	exonic
CAediting_745146	chr10_37955822_-	ncRNA_intronic
CAediting_745147	chr10_37955947_-	ncRNA_intronic
CAediting_745148	chr10_37956787_-	ncRNA_intronic
CAediting_745149	chr10_37956793_-	ncRNA_intronic
CAediting_745150	chr10_37956839_-	ncRNA_intronic
CAediting_745151	chr10_37956852_-	ncRNA_intronic
CAediting_745152	chr10_37956853_-	ncRNA_intronic
CAediting_745153	chr10_37956858_-	ncRNA_intronic
CAediting_745154	chr10_37956863_-	ncRNA_intronic
CAediting_745155	chr10_37958769_-	ncRNA_intronic
CAediting_745156	chr10_37958791_-	ncRNA_intronic
CAediting_745157	chr10_37958937_-	ncRNA_intronic
CAediting_745158	chr10_37958949_-	ncRNA_intronic
CAediting_745159	chr10_37959005_-	ncRNA_intronic
CAediting_745160	chr10_37959022_-	ncRNA_intronic
CAediting_745161	chr10_37959023_-	ncRNA_intronic
CAediting_745162	chr10_37959047_-	ncRNA_intronic
CAediting_745163	chr10_37959624_-	ncRNA_intronic
CAediting_745164	chr10_37959625_-	ncRNA_intronic
CAediting_745165	chr10_37959675_-	ncRNA_intronic
CAediting_745166	chr10_37959677_-	ncRNA_intronic
CAediting_745167	chr10_37959710_-	ncRNA_intronic
CAediting_745168	chr10_37959779_-	ncRNA_intronic
CAediting_745169	chr10_37959780_-	ncRNA_intronic
CAediting_745170	chr10_37960053_-	ncRNA_intronic
CAediting_745171	chr10_37960055_-	ncRNA_intronic
CAediting_745172	chr10_37960082_-	ncRNA_intronic
CAediting_745173	chr10_37960083_-	ncRNA_intronic
CAediting_745174	chr10_37963171_-	ncRNA_intronic
CAediting_745175	chr10_37963715_-	ncRNA_intronic
CAediting_745176	chr10_37963716_-	ncRNA_intronic
CAediting_745177	chr10_37963730_-	ncRNA_intronic
CAediting_745178	chr10_37963731_-	ncRNA_intronic
CAediting_745179	chr10_37963758_-	ncRNA_intronic
CAediting_745180	chr10_37963809_-	ncRNA_intronic
CAediting_745181	chr10_37963853_-	ncRNA_intronic
CAediting_745182	chr10_37963858_-	ncRNA_intronic
CAediting_745183	chr10_37963863_-	ncRNA_intronic
CAediting_745184	chr10_37963875_-	ncRNA_intronic
CAediting_745185	chr10_37963899_-	ncRNA_intronic
CAediting_745186	chr10_37963961_-	ncRNA_intronic
CAediting_745187	chr10_37963973_-	ncRNA_intronic
CAediting_745188	chr10_37964032_-	ncRNA_intronic
CAediting_745189	chr10_37964048_-	ncRNA_intronic
CAediting_745190	chr10_37964070_-	ncRNA_intronic
CAediting_745191	chr10_37964075_-	ncRNA_intronic
CAediting_745192	chr10_37964076_-	ncRNA_intronic
CAediting_745193	chr10_37964179_-	ncRNA_intronic
CAediting_745194	chr10_37964185_-	ncRNA_intronic
CAediting_745195	chr10_37966305_-	ncRNA_intronic
CAediting_745196	chr10_37966691_-	ncRNA_intronic
CAediting_745197	chr10_37967470_-	ncRNA_intronic
CAediting_745198	chr10_37967482_-	ncRNA_intronic
CAediting_745199	chr10_37967483_-	ncRNA_intronic
CAediting_745200	chr10_37967486_-	ncRNA_intronic
CAediting_745201	chr10_37967508_-	ncRNA_intronic
CAediting_745202	chr10_37967513_-	ncRNA_intronic
CAediting_745203	chr10_37967543_-	ncRNA_intronic
CAediting_745204	chr10_37967549_-	ncRNA_intronic
CAediting_745205	chr10_37967570_-	ncRNA_intronic
CAediting_745206	chr10_37967574_-	ncRNA_intronic
CAediting_745207	chr10_37967577_-	ncRNA_intronic
CAediting_745208	chr10_37967583_-	ncRNA_intronic
CAediting_745209	chr10_37967587_-	ncRNA_intronic
CAediting_745210	chr10_37967625_-	ncRNA_intronic
CAediting_745211	chr10_37967650_-	ncRNA_intronic
CAediting_745212	chr10_37967667_-	ncRNA_intronic
CAediting_745213	chr10_37967674_-	ncRNA_intronic
CAediting_745214	chr10_37968233_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_745146	chr10_37955822_-	SINE	Alu	AluSz6
CAediting_745147	chr10_37955947_-	SINE	Alu	AluSz6
CAediting_745148	chr10_37956787_-	SINE	Alu	AluSp
CAediting_745149	chr10_37956793_-	SINE	Alu	AluSp
CAediting_745150	chr10_37956839_-	SINE	Alu	AluSp
CAediting_745151	chr10_37956852_-	SINE	Alu	AluSp
CAediting_745152	chr10_37956853_-	SINE	Alu	AluSp
CAediting_745153	chr10_37956858_-	SINE	Alu	AluSp
CAediting_745154	chr10_37956863_-	SINE	Alu	AluSp
CAediting_745155	chr10_37958769_-	SINE	Alu	AluSx
CAediting_745156	chr10_37958791_-	SINE	Alu	AluSx
CAediting_745157	chr10_37958937_-	SINE	Alu	AluSx
CAediting_745158	chr10_37958949_-	SINE	Alu	AluSx
CAediting_745159	chr10_37959005_-	SINE	Alu	AluSx
CAediting_745160	chr10_37959022_-	SINE	Alu	AluSx
CAediting_745161	chr10_37959023_-	SINE	Alu	AluSx
CAediting_745162	chr10_37959047_-	SINE	Alu	AluSx
CAediting_745163	chr10_37959624_-	SINE	Alu	AluSx1
CAediting_745164	chr10_37959625_-	SINE	Alu	AluSx1
CAediting_745165	chr10_37959675_-	SINE	Alu	AluSx1
CAediting_745166	chr10_37959677_-	SINE	Alu	AluSx1
CAediting_745167	chr10_37959710_-	SINE	Alu	AluSx1
CAediting_745168	chr10_37959779_-	SINE	Alu	AluSx1
CAediting_745169	chr10_37959780_-	SINE	Alu	AluSx1
CAediting_745170	chr10_37960053_-	SINE	Alu	AluYh3
CAediting_745171	chr10_37960055_-	SINE	Alu	AluYh3
CAediting_745172	chr10_37960082_-	SINE	Alu	AluYh3
CAediting_745173	chr10_37960083_-	SINE	Alu	AluYh3
CAediting_745174	chr10_37963171_-	SINE	Alu	AluSx1
CAediting_745175	chr10_37963715_-	SINE	Alu	AluSx
CAediting_745176	chr10_37963716_-	SINE	Alu	AluSx
CAediting_745177	chr10_37963730_-	SINE	Alu	AluSx
CAediting_745178	chr10_37963731_-	SINE	Alu	AluSx
CAediting_745179	chr10_37963758_-	SINE	Alu	AluSx
CAediting_745180	chr10_37963809_-	SINE	Alu	AluSx
CAediting_745181	chr10_37963853_-	SINE	Alu	AluSx
CAediting_745182	chr10_37963858_-	SINE	Alu	AluSx
CAediting_745183	chr10_37963863_-	SINE	Alu	AluSx
CAediting_745184	chr10_37963875_-	SINE	Alu	AluSx
CAediting_745185	chr10_37963899_-	SINE	Alu	AluSx
CAediting_745186	chr10_37963961_-	SINE	Alu	AluSx
CAediting_745187	chr10_37963973_-	SINE	Alu	AluSx
CAediting_745188	chr10_37964032_-	LTR	ERVL-MaLR	MSTB
CAediting_745189	chr10_37964048_-	LTR	ERVL-MaLR	MSTB
CAediting_745190	chr10_37964070_-	LTR	ERVL-MaLR	MSTB
CAediting_745191	chr10_37964075_-	LTR	ERVL-MaLR	MSTB
CAediting_745192	chr10_37964076_-	LTR	ERVL-MaLR	MSTB
CAediting_745193	chr10_37964179_-	LTR	ERVL-MaLR	MSTB
CAediting_745194	chr10_37964185_-	LTR	ERVL-MaLR	MSTB
CAediting_745195	chr10_37966305_-	SINE	Alu	AluSz
CAediting_745196	chr10_37966691_-	LTR	ERVL-MaLR	MSTA
CAediting_745197	chr10_37967470_-	SINE	Alu	AluJb
CAediting_745198	chr10_37967482_-	SINE	Alu	AluJb
CAediting_745199	chr10_37967483_-	SINE	Alu	AluJb
CAediting_745200	chr10_37967486_-	SINE	Alu	AluJb
CAediting_745201	chr10_37967508_-	SINE	Alu	AluJb
CAediting_745202	chr10_37967513_-	SINE	Alu	AluJb
CAediting_745203	chr10_37967543_-	SINE	Alu	AluJb
CAediting_745204	chr10_37967549_-	SINE	Alu	AluJb
CAediting_745205	chr10_37967570_-	SINE	Alu	AluJb
CAediting_745206	chr10_37967574_-	SINE	Alu	AluJb
CAediting_745207	chr10_37967577_-	SINE	Alu	AluJb
CAediting_745208	chr10_37967583_-	SINE	Alu	AluJb
CAediting_745209	chr10_37967587_-	SINE	Alu	AluJb
CAediting_745210	chr10_37967625_-	SINE	Alu	AluJb
CAediting_745211	chr10_37967650_-	SINE	Alu	AluJb
CAediting_745212	chr10_37967667_-	SINE	Alu	AluJb
CAediting_745213	chr10_37967674_-	SINE	Alu	AluJb
CAediting_745214	chr10_37968233_-	SINE	Alu	AluSx4

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RNA A-to-I editing events in the alternative splicing sites for ZNF25

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
ES	CAediting_745148	chr10_37956787_-	37956783:37956791	5SS	0+2i	AGGCATGTA	-24.44	AGGCGTGTA	-23.9

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000175395.14.ZNF25.

Correlation between RNA A-to-I editing and PSI for ENSG00000175395.14.ZNF25.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF25

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for ZNF25

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for ZNF25

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ZNF25

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for ZNF25

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for ZNF25

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for ZNF25

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for ZNF25

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for ZNF25

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene