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Editing gene: F2 (CAeditome ID:2147)

Gene summary for F2

Gene summary

Gene information	Gene symbol	F2
	Gene ID	2147
	Gene name	coagulation factor II, thrombin
	Synonyms	PT\|RPRGL2\|THPH1
	Cytomap	11p11.2
	Type of gene	protein-coding
	Description	prothrombinprepro-coagulation factor IIprothrombin B-chainthrombin factor II
	Modification date	20210518
	UniProtAcc	P00734
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
F2	GO:0009897	Prothrombin	20421939
F2	GO:0001530	Prothrombin	20421939
F2	GO:0004252	Prothrombin	12855810
F2	GO:0004252	Prothrombin	1672265
F2	GO:0008201	Prothrombin	20421939
F2	GO:0070053	Prothrombin	2435757
F2	GO:0001934	Prothrombin	7559487
F2	GO:0007166	Prothrombin	1672265
F2	GO:0009611	Prothrombin	9639571
F2	GO:0030168	Prothrombin	9038223
F2	GO:0030194	Prothrombin	9038223
F2	GO:0032967	Prothrombin	9639571
F2	GO:0042730	Prothrombin	12855810
F2	GO:0045861	Prothrombin	1695900
F2	GO:0048712	Prothrombin	1691280
F2	GO:0051281	Prothrombin	1672265
F2	GO:0051281	Prothrombin	19052258
F2	GO:0051480	Prothrombin	19052258
F2	GO:0051838	Prothrombin	20421939
F2	GO:0051838	Prothrombin	20421939
F2	GO:0061844	Prothrombin	20421939
F2	GO:0070945	Prothrombin	20421939
F2	GO:0070945	Prothrombin	20421939
F2	GO:0090218	Prothrombin	11309392
F2	GO:1900016	Prothrombin	20421939
F2	GO:1900182	Prothrombin	11309392
F2	GO:1900738	Prothrombin	20164183
F2	GO:2000379	Prothrombin	17275676
F2	GO:0005615	Prothrombin	20421939
F2	GO:0005615	Prothrombin	9639571

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RNA A-to-I events for F2

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000180210.13

RNA A-to-I editing events in Cancer.

CAediting_808892(46721901, +), CAediting_808893(46721972, +), CAediting_808894(46721982, +), CAediting_808895(46721988, +), CAediting_808896(46722119, +), CAediting_808897(46722328, +), CAediting_808898(46722329, +), CAediting_808899(46722336, +), CAediting_808900(46722337, +), CAediting_808901(46722384, +), CAediting_808902(46722386, +), CAediting_808903(46722403, +), CAediting_808904(46722422, +), CAediting_808905(46722425, +), CAediting_808906(46722426, +), CAediting_808907(46722427, +), CAediting_808908(46722431, +), CAediting_808909(46722436, +), CAediting_808910(46722437, +), CAediting_808911(46722440, +), CAediting_808912(46722468, +), CAediting_808913(46722477, +), CAediting_808914(46722480, +), CAediting_808915(46722520, +), CAediting_808916(46722548, +), CAediting_808917(46727500, +), CAediting_808918(46727522, +), CAediting_808919(46727523, +), CAediting_808920(46727528, +), CAediting_808921(46727545, +), CAediting_808922(46727553, +), CAediting_808923(46727563, +), CAediting_808924(46727582, +), CAediting_808925(46727599, +), CAediting_808926(46727600, +), CAediting_808927(46727602, +), CAediting_808928(46727616, +), CAediting_808929(46727620, +), CAediting_808930(46727635, +), CAediting_808931(46727657, +), CAediting_808932(46727671, +), CAediting_808933(46727698, +), CAediting_808934(46727703, +), CAediting_808935(46727722, +), CAediting_808936(46729254, +), CAediting_808937(46730049, +), CAediting_808938(46730075, +), CAediting_808939(46730090, +), CAediting_808940(46730098, +), CAediting_808941(46730099, +), CAediting_808942(46730138, +), CAediting_808943(46730140, +), CAediting_808944(46730147, +), CAediting_808945(46730148, +), CAediting_808946(46730149, +), CAediting_808947(46730150, +), CAediting_808948(46730179, +), CAediting_808949(46730189, +), CAediting_808950(46730202, +), CAediting_808951(46730212, +), CAediting_808952(46730220, +), CAediting_808953(46730224, +), CAediting_808954(46730288, +), CAediting_808955(46731252, +), CAediting_808956(46732015, +), CAediting_808957(46732016, +), CAediting_808958(46732099, +), CAediting_808959(46732176, +), CAediting_808960(46732454, +), CAediting_808961(46732477, +), CAediting_808962(46733273, +), CAediting_808963(46733304, +), CAediting_808964(46733316, +), CAediting_808965(46733333, +), CAediting_808966(46733337, +), CAediting_808967(46733343, +), CAediting_808968(46733345, +), CAediting_808969(46733413, +), CAediting_808970(46733415, +), CAediting_808971(46733417, +), CAediting_808972(46733437, +), CAediting_808973(46733438, +), CAediting_808974(46733464, +), CAediting_808975(46733477, +), CAediting_808976(46733889, +), CAediting_808977(46733906, +), CAediting_808978(46733953, +), CAediting_808979(46733954, +), CAediting_808980(46733962, +), CAediting_808981(46733997, +), CAediting_808982(46734060, +), CAediting_808983(46734197, +), CAediting_808984(46734198, +), CAediting_808985(46734550, +), CAediting_808986(46734556, +), CAediting_808987(46734557, +), CAediting_808988(46734571, +), CAediting_808989(46734591, +), CAediting_808990(46734690, +), CAediting_808991(46734696, +), CAediting_808992(46734700, +), CAediting_808993(46734704, +), CAediting_808994(46734731, +), CAediting_808995(46734732, +), CAediting_808996(46735038, +), CAediting_808997(46735046, +), CAediting_808998(46735051, +), CAediting_808999(46735053, +), CAediting_809000(46735059, +), CAediting_809001(46735060, +), CAediting_809002(46735106, +), CAediting_809003(46735110, +), CAediting_809004(46735112, +), CAediting_809005(46735113, +), CAediting_809006(46735121, +), CAediting_809007(46735126, +), CAediting_809008(46735130, +), CAediting_809009(46735133, +), CAediting_809010(46735186, +), CAediting_809011(46735320, +), CAediting_809012(46735334, +), CAediting_809013(46735502, +), CAediting_809014(46735548, +), CAediting_809015(46735559, +), CAediting_809016(46735580, +), CAediting_809017(46736361, +), CAediting_809018(46736383, +), CAediting_809019(46736384, +), CAediting_809020(46736385, +), CAediting_809021(46736397, +), CAediting_809022(46736399, +), CAediting_809023(46736481, +), CAediting_809024(46736483, +), CAediting_809025(46736503, +), CAediting_809026(46736507, +), CAediting_809027(46736560, +), CAediting_809028(46736572, +), CAediting_809029(46736578, +), CAediting_809030(46737857, +), CAediting_809031(46737908, +), CAediting_809032(46737913, +), CAediting_809033(46737934, +), CAediting_809034(46737937, +), CAediting_809035(46737970, +), CAediting_809036(46737976, +), CAediting_809037(46738053, +), CAediting_809038(46738072, +), CAediting_809039(46738104, +), CAediting_809040(46738107, +), CAediting_809041(46738108, +), CAediting_809042(46738113, +), CAediting_809043(46738118, +), CAediting_809044(46738130, +), CAediting_809045(46738140, +), CAediting_809046(46738142, +), CAediting_809047(46738166, +), CAediting_809048(46738167, +), CAediting_809049(46738175, +), CAediting_809050(46738181, +), CAediting_809051(46738184, +), CAediting_809052(46738198, +), CAediting_809053(46738210, +), CAediting_809054(46738221, +), CAediting_809055(46738222, +), CAediting_809056(46738260, +), CAediting_809057(46738261, +), CAediting_809058(46738268, +), CAediting_809059(46738273, +), CAediting_809060(46738497, +), CAediting_809061(46738505, +), CAediting_809062(46738541, +), CAediting_809063(46738548, +), CAediting_809064(46738553, +), CAediting_809065(46738559, +), CAediting_809066(46738567, +), CAediting_809067(46738574, +), CAediting_809068(46738600, +), CAediting_809069(46738603, +), CAediting_809070(46738610, +), CAediting_809071(46738615, +), CAediting_809072(46738619, +), CAediting_809073(46738653, +), CAediting_809074(46738655, +), CAediting_809075(46738666, +), CAediting_809076(46738668, +), CAediting_809077(46738675, +),

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RNA editing positional annotations for F2 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_808892	chr11_46721901_+	intronic
CAediting_808893	chr11_46721972_+	intronic
CAediting_808894	chr11_46721982_+	intronic
CAediting_808895	chr11_46721988_+	intronic
CAediting_808896	chr11_46722119_+	intronic
CAediting_808897	chr11_46722328_+	intronic
CAediting_808898	chr11_46722329_+	intronic
CAediting_808899	chr11_46722336_+	intronic
CAediting_808900	chr11_46722337_+	intronic
CAediting_808901	chr11_46722384_+	intronic
CAediting_808902	chr11_46722386_+	intronic
CAediting_808903	chr11_46722403_+	intronic
CAediting_808904	chr11_46722422_+	intronic
CAediting_808905	chr11_46722425_+	intronic
CAediting_808906	chr11_46722426_+	intronic
CAediting_808907	chr11_46722427_+	intronic
CAediting_808908	chr11_46722431_+	intronic
CAediting_808909	chr11_46722436_+	intronic
CAediting_808910	chr11_46722437_+	intronic
CAediting_808911	chr11_46722440_+	intronic
CAediting_808912	chr11_46722468_+	intronic
CAediting_808913	chr11_46722477_+	intronic
CAediting_808914	chr11_46722480_+	intronic
CAediting_808915	chr11_46722520_+	intronic
CAediting_808916	chr11_46722548_+	intronic
CAediting_808917	chr11_46727500_+	intronic
CAediting_808918	chr11_46727522_+	intronic
CAediting_808919	chr11_46727523_+	intronic
CAediting_808920	chr11_46727528_+	intronic
CAediting_808921	chr11_46727545_+	intronic
CAediting_808922	chr11_46727553_+	intronic
CAediting_808923	chr11_46727563_+	intronic
CAediting_808924	chr11_46727582_+	intronic
CAediting_808925	chr11_46727599_+	intronic
CAediting_808926	chr11_46727600_+	intronic
CAediting_808927	chr11_46727602_+	intronic
CAediting_808928	chr11_46727616_+	intronic
CAediting_808929	chr11_46727620_+	intronic
CAediting_808930	chr11_46727635_+	intronic
CAediting_808931	chr11_46727657_+	intronic
CAediting_808932	chr11_46727671_+	intronic
CAediting_808933	chr11_46727698_+	intronic
CAediting_808934	chr11_46727703_+	intronic
CAediting_808935	chr11_46727722_+	intronic
CAediting_808936	chr11_46729254_+	intronic
CAediting_808937	chr11_46730049_+	intronic
CAediting_808938	chr11_46730075_+	intronic
CAediting_808939	chr11_46730090_+	intronic
CAediting_808940	chr11_46730098_+	intronic
CAediting_808941	chr11_46730099_+	intronic
CAediting_808942	chr11_46730138_+	intronic
CAediting_808943	chr11_46730140_+	intronic
CAediting_808944	chr11_46730147_+	intronic
CAediting_808945	chr11_46730148_+	intronic
CAediting_808946	chr11_46730149_+	intronic
CAediting_808947	chr11_46730150_+	intronic
CAediting_808948	chr11_46730179_+	intronic
CAediting_808949	chr11_46730189_+	intronic
CAediting_808950	chr11_46730202_+	intronic
CAediting_808951	chr11_46730212_+	intronic
CAediting_808952	chr11_46730220_+	intronic
CAediting_808953	chr11_46730224_+	intronic
CAediting_808954	chr11_46730288_+	intronic
CAediting_808955	chr11_46731252_+	intronic
CAediting_808956	chr11_46732015_+	intronic
CAediting_808957	chr11_46732016_+	intronic
CAediting_808958	chr11_46732099_+	intronic
CAediting_808959	chr11_46732176_+	intronic
CAediting_808960	chr11_46732454_+	intronic
CAediting_808961	chr11_46732477_+	intronic
CAediting_808962	chr11_46733273_+	intronic
CAediting_808963	chr11_46733304_+	intronic
CAediting_808964	chr11_46733316_+	intronic
CAediting_808965	chr11_46733333_+	intronic
CAediting_808966	chr11_46733337_+	intronic
CAediting_808967	chr11_46733343_+	intronic
CAediting_808968	chr11_46733345_+	intronic
CAediting_808969	chr11_46733413_+	intronic
CAediting_808970	chr11_46733415_+	intronic
CAediting_808971	chr11_46733417_+	intronic
CAediting_808972	chr11_46733437_+	intronic
CAediting_808973	chr11_46733438_+	intronic
CAediting_808974	chr11_46733464_+	intronic
CAediting_808975	chr11_46733477_+	intronic
CAediting_808976	chr11_46733889_+	intronic
CAediting_808977	chr11_46733906_+	intronic
CAediting_808978	chr11_46733953_+	intronic
CAediting_808979	chr11_46733954_+	intronic
CAediting_808980	chr11_46733962_+	intronic
CAediting_808981	chr11_46733997_+	intronic
CAediting_808982	chr11_46734060_+	intronic
CAediting_808983	chr11_46734197_+	intronic
CAediting_808984	chr11_46734198_+	intronic
CAediting_808985	chr11_46734550_+	intronic
CAediting_808986	chr11_46734556_+	intronic
CAediting_808987	chr11_46734557_+	intronic
CAediting_808988	chr11_46734571_+	intronic
CAediting_808989	chr11_46734591_+	intronic
CAediting_808990	chr11_46734690_+	intronic
CAediting_808991	chr11_46734696_+	intronic
CAediting_808992	chr11_46734700_+	intronic
CAediting_808993	chr11_46734704_+	intronic
CAediting_808994	chr11_46734731_+	intronic
CAediting_808995	chr11_46734732_+	intronic
CAediting_808996	chr11_46735038_+	intronic
CAediting_808997	chr11_46735046_+	intronic
CAediting_808998	chr11_46735051_+	intronic
CAediting_808999	chr11_46735053_+	intronic
CAediting_809000	chr11_46735059_+	intronic
CAediting_809001	chr11_46735060_+	intronic
CAediting_809002	chr11_46735106_+	intronic
CAediting_809003	chr11_46735110_+	intronic
CAediting_809004	chr11_46735112_+	intronic
CAediting_809005	chr11_46735113_+	intronic
CAediting_809006	chr11_46735121_+	intronic
CAediting_809007	chr11_46735126_+	intronic
CAediting_809008	chr11_46735130_+	intronic
CAediting_809009	chr11_46735133_+	intronic
CAediting_809010	chr11_46735186_+	intronic
CAediting_809011	chr11_46735320_+	intronic
CAediting_809012	chr11_46735334_+	intronic
CAediting_809013	chr11_46735502_+	intronic
CAediting_809014	chr11_46735548_+	intronic
CAediting_809015	chr11_46735559_+	intronic
CAediting_809016	chr11_46735580_+	intronic
CAediting_809017	chr11_46736361_+	intronic
CAediting_809018	chr11_46736383_+	intronic
CAediting_809019	chr11_46736384_+	intronic
CAediting_809020	chr11_46736385_+	intronic
CAediting_809021	chr11_46736397_+	intronic
CAediting_809022	chr11_46736399_+	intronic
CAediting_809023	chr11_46736481_+	intronic
CAediting_809024	chr11_46736483_+	intronic
CAediting_809025	chr11_46736503_+	intronic
CAediting_809026	chr11_46736507_+	intronic
CAediting_809027	chr11_46736560_+	intronic
CAediting_809028	chr11_46736572_+	intronic
CAediting_809029	chr11_46736578_+	intronic
CAediting_809030	chr11_46737857_+	intronic
CAediting_809031	chr11_46737908_+	intronic
CAediting_809032	chr11_46737913_+	intronic
CAediting_809033	chr11_46737934_+	intronic
CAediting_809034	chr11_46737937_+	intronic
CAediting_809035	chr11_46737970_+	intronic
CAediting_809036	chr11_46737976_+	intronic
CAediting_809037	chr11_46738053_+	intronic
CAediting_809038	chr11_46738072_+	intronic
CAediting_809039	chr11_46738104_+	intronic
CAediting_809040	chr11_46738107_+	intronic
CAediting_809041	chr11_46738108_+	intronic
CAediting_809042	chr11_46738113_+	intronic
CAediting_809043	chr11_46738118_+	intronic
CAediting_809044	chr11_46738130_+	intronic
CAediting_809045	chr11_46738140_+	intronic
CAediting_809046	chr11_46738142_+	intronic
CAediting_809047	chr11_46738166_+	intronic
CAediting_809048	chr11_46738167_+	intronic
CAediting_809049	chr11_46738175_+	intronic
CAediting_809050	chr11_46738181_+	intronic
CAediting_809051	chr11_46738184_+	intronic
CAediting_809052	chr11_46738198_+	intronic
CAediting_809053	chr11_46738210_+	intronic
CAediting_809054	chr11_46738221_+	intronic
CAediting_809055	chr11_46738222_+	intronic
CAediting_809056	chr11_46738260_+	intronic
CAediting_809057	chr11_46738261_+	intronic
CAediting_809058	chr11_46738268_+	intronic
CAediting_809059	chr11_46738273_+	intronic
CAediting_809060	chr11_46738497_+	intronic
CAediting_809061	chr11_46738505_+	intronic
CAediting_809062	chr11_46738541_+	intronic
CAediting_809063	chr11_46738548_+	intronic
CAediting_809064	chr11_46738553_+	intronic
CAediting_809065	chr11_46738559_+	intronic
CAediting_809066	chr11_46738567_+	intronic
CAediting_809067	chr11_46738574_+	intronic
CAediting_809068	chr11_46738600_+	intronic
CAediting_809069	chr11_46738603_+	intronic
CAediting_809070	chr11_46738610_+	intronic
CAediting_809071	chr11_46738615_+	intronic
CAediting_809072	chr11_46738619_+	intronic
CAediting_809073	chr11_46738653_+	intronic
CAediting_809074	chr11_46738655_+	intronic
CAediting_809075	chr11_46738666_+	intronic
CAediting_809076	chr11_46738668_+	intronic
CAediting_809077	chr11_46738675_+	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_808892	chr11_46721901_+	SINE	Alu	AluSx
CAediting_808893	chr11_46721972_+	SINE	Alu	AluSx
CAediting_808894	chr11_46721982_+	SINE	Alu	AluSx
CAediting_808895	chr11_46721988_+	SINE	Alu	AluSx
CAediting_808896	chr11_46722119_+	SINE	Alu	AluSx
CAediting_808897	chr11_46722328_+	SINE	Alu	AluSx
CAediting_808898	chr11_46722329_+	SINE	Alu	AluSx
CAediting_808899	chr11_46722336_+	SINE	Alu	AluSx
CAediting_808900	chr11_46722337_+	SINE	Alu	AluSx
CAediting_808901	chr11_46722384_+	SINE	Alu	AluSx
CAediting_808902	chr11_46722386_+	SINE	Alu	AluSx
CAediting_808903	chr11_46722403_+	SINE	Alu	AluSx
CAediting_808904	chr11_46722422_+	SINE	Alu	AluSx
CAediting_808905	chr11_46722425_+	SINE	Alu	AluSx
CAediting_808906	chr11_46722426_+	SINE	Alu	AluSx
CAediting_808907	chr11_46722427_+	SINE	Alu	AluSx
CAediting_808908	chr11_46722431_+	SINE	Alu	AluSx
CAediting_808909	chr11_46722436_+	SINE	Alu	AluSx
CAediting_808910	chr11_46722437_+	SINE	Alu	AluSx
CAediting_808911	chr11_46722440_+	SINE	Alu	AluSx
CAediting_808912	chr11_46722468_+	SINE	Alu	AluSx
CAediting_808913	chr11_46722477_+	SINE	Alu	AluSx
CAediting_808914	chr11_46722480_+	SINE	Alu	AluSx
CAediting_808915	chr11_46722520_+	SINE	Alu	AluSx
CAediting_808916	chr11_46722548_+	SINE	Alu	AluSx
CAediting_808917	chr11_46727500_+	SINE	Alu	AluJb
CAediting_808918	chr11_46727522_+	SINE	Alu	AluJb
CAediting_808919	chr11_46727523_+	SINE	Alu	AluJb
CAediting_808920	chr11_46727528_+	SINE	Alu	AluJb
CAediting_808921	chr11_46727545_+	SINE	Alu	AluJb
CAediting_808922	chr11_46727553_+	SINE	Alu	AluJb
CAediting_808923	chr11_46727563_+	SINE	Alu	AluJb
CAediting_808924	chr11_46727582_+	SINE	Alu	AluJb
CAediting_808925	chr11_46727599_+	SINE	Alu	AluJb
CAediting_808926	chr11_46727600_+	SINE	Alu	AluJb
CAediting_808927	chr11_46727602_+	SINE	Alu	AluJb
CAediting_808928	chr11_46727616_+	SINE	Alu	AluJb
CAediting_808929	chr11_46727620_+	SINE	Alu	AluJb
CAediting_808930	chr11_46727635_+	SINE	Alu	AluJb
CAediting_808931	chr11_46727657_+	SINE	Alu	AluJb
CAediting_808932	chr11_46727671_+	SINE	Alu	AluJb
CAediting_808933	chr11_46727698_+	SINE	Alu	AluJb
CAediting_808934	chr11_46727703_+	SINE	Alu	AluJb
CAediting_808935	chr11_46727722_+	SINE	Alu	AluJb
CAediting_808936	chr11_46729254_+	SINE	Alu	AluSq2
CAediting_808937	chr11_46730049_+	LINE	L2	L2a
CAediting_808938	chr11_46730075_+	SINE	Alu	AluSz
CAediting_808939	chr11_46730090_+	SINE	Alu	AluSz
CAediting_808940	chr11_46730098_+	SINE	Alu	AluSz
CAediting_808941	chr11_46730099_+	SINE	Alu	AluSz
CAediting_808942	chr11_46730138_+	SINE	Alu	AluSz
CAediting_808943	chr11_46730140_+	SINE	Alu	AluSz
CAediting_808944	chr11_46730147_+	SINE	Alu	AluSz
CAediting_808945	chr11_46730148_+	SINE	Alu	AluSz
CAediting_808946	chr11_46730149_+	SINE	Alu	AluSz
CAediting_808947	chr11_46730150_+	SINE	Alu	AluSz
CAediting_808948	chr11_46730179_+	SINE	Alu	AluSz
CAediting_808949	chr11_46730189_+	SINE	Alu	AluSz
CAediting_808950	chr11_46730202_+	SINE	Alu	AluSz
CAediting_808951	chr11_46730212_+	SINE	Alu	AluSz
CAediting_808952	chr11_46730220_+	SINE	Alu	AluSz
CAediting_808953	chr11_46730224_+	SINE	Alu	AluSz
CAediting_808954	chr11_46730288_+	SINE	Alu	AluSz
CAediting_808955	chr11_46731252_+	SINE	Alu	AluSx1
CAediting_808956	chr11_46732015_+	SINE	Alu	AluSg
CAediting_808957	chr11_46732016_+	SINE	Alu	AluSg
CAediting_808958	chr11_46732099_+	SINE	Alu	AluSg
CAediting_808959	chr11_46732176_+	SINE	Alu	AluSg
CAediting_808960	chr11_46732454_+	SINE	Alu	AluSq2
CAediting_808961	chr11_46732477_+	SINE	Alu	AluSq2
CAediting_808962	chr11_46733273_+	SINE	Alu	AluJb
CAediting_808963	chr11_46733304_+	SINE	Alu	AluJb
CAediting_808964	chr11_46733316_+	SINE	Alu	AluJb
CAediting_808965	chr11_46733333_+	SINE	Alu	AluJb
CAediting_808966	chr11_46733337_+	SINE	Alu	AluJb
CAediting_808967	chr11_46733343_+	SINE	Alu	AluJb
CAediting_808968	chr11_46733345_+	SINE	Alu	AluJb
CAediting_808969	chr11_46733413_+	SINE	Alu	AluJb
CAediting_808970	chr11_46733415_+	SINE	Alu	AluJb
CAediting_808971	chr11_46733417_+	SINE	Alu	AluJb
CAediting_808972	chr11_46733437_+	SINE	Alu	AluJb
CAediting_808973	chr11_46733438_+	SINE	Alu	AluJb
CAediting_808974	chr11_46733464_+	SINE	Alu	AluJb
CAediting_808975	chr11_46733477_+	SINE	Alu	AluJb
CAediting_808976	chr11_46733889_+	SINE	Alu	AluSx3
CAediting_808977	chr11_46733906_+	SINE	Alu	AluSx3
CAediting_808978	chr11_46733953_+	SINE	Alu	AluSx3
CAediting_808979	chr11_46733954_+	SINE	Alu	AluSx3
CAediting_808980	chr11_46733962_+	SINE	Alu	AluSx3
CAediting_808981	chr11_46733997_+	SINE	Alu	AluSx3
CAediting_808982	chr11_46734060_+	SINE	Alu	AluSx3
CAediting_808983	chr11_46734197_+	SINE	Alu	AluSx
CAediting_808984	chr11_46734198_+	SINE	Alu	AluSx
CAediting_808985	chr11_46734550_+	SINE	Alu	AluSx1
CAediting_808986	chr11_46734556_+	SINE	Alu	AluSx1
CAediting_808987	chr11_46734557_+	SINE	Alu	AluSx1
CAediting_808988	chr11_46734571_+	SINE	Alu	AluSx1
CAediting_808989	chr11_46734591_+	SINE	Alu	AluSx1
CAediting_808990	chr11_46734690_+	SINE	Alu	AluSx1
CAediting_808991	chr11_46734696_+	SINE	Alu	AluSx1
CAediting_808992	chr11_46734700_+	SINE	Alu	AluSx1
CAediting_808993	chr11_46734704_+	SINE	Alu	AluSx1
CAediting_808994	chr11_46734731_+	SINE	Alu	AluSx1
CAediting_808995	chr11_46734732_+	SINE	Alu	AluSx1
CAediting_808996	chr11_46735038_+	SINE	Alu	AluJr
CAediting_808997	chr11_46735046_+	SINE	Alu	AluJr
CAediting_808998	chr11_46735051_+	SINE	Alu	AluJr
CAediting_808999	chr11_46735053_+	SINE	Alu	AluJr
CAediting_809000	chr11_46735059_+	SINE	Alu	AluJr
CAediting_809001	chr11_46735060_+	SINE	Alu	AluJr
CAediting_809002	chr11_46735106_+	SINE	Alu	AluJr
CAediting_809003	chr11_46735110_+	SINE	Alu	AluJr
CAediting_809004	chr11_46735112_+	SINE	Alu	AluJr
CAediting_809005	chr11_46735113_+	SINE	Alu	AluJr
CAediting_809006	chr11_46735121_+	SINE	Alu	AluJr
CAediting_809007	chr11_46735126_+	SINE	Alu	AluJr
CAediting_809008	chr11_46735130_+	SINE	Alu	AluJr
CAediting_809009	chr11_46735133_+	SINE	Alu	AluJr
CAediting_809010	chr11_46735186_+	SINE	Alu	AluSc
CAediting_809011	chr11_46735320_+	SINE	Alu	AluSc
CAediting_809012	chr11_46735334_+	SINE	Alu	AluSc
CAediting_809013	chr11_46735502_+	SINE	Alu	AluJr
CAediting_809014	chr11_46735548_+	SINE	Alu	AluJr
CAediting_809015	chr11_46735559_+	SINE	Alu	AluJr
CAediting_809016	chr11_46735580_+	SINE	Alu	AluJr
CAediting_809017	chr11_46736361_+	SINE	Alu	FLAM_C
CAediting_809018	chr11_46736383_+	SINE	Alu	FLAM_C
CAediting_809019	chr11_46736384_+	SINE	Alu	FLAM_C
CAediting_809020	chr11_46736385_+	SINE	Alu	FLAM_C
CAediting_809021	chr11_46736397_+	SINE	Alu	FLAM_C
CAediting_809022	chr11_46736399_+	SINE	Alu	FLAM_C
CAediting_809023	chr11_46736481_+	SINE	Alu	AluJo
CAediting_809024	chr11_46736483_+	SINE	Alu	AluJo
CAediting_809025	chr11_46736503_+	SINE	Alu	AluJo
CAediting_809026	chr11_46736507_+	SINE	Alu	AluJo
CAediting_809027	chr11_46736560_+	SINE	Alu	AluJo
CAediting_809028	chr11_46736572_+	SINE	Alu	AluJo
CAediting_809029	chr11_46736578_+	SINE	Alu	AluJo
CAediting_809030	chr11_46737857_+	SINE	Alu	AluJo
CAediting_809031	chr11_46737908_+	SINE	Alu	AluJo
CAediting_809032	chr11_46737913_+	SINE	Alu	AluJo
CAediting_809033	chr11_46737934_+	SINE	Alu	AluJo
CAediting_809034	chr11_46737937_+	SINE	Alu	AluJo
CAediting_809035	chr11_46737970_+	SINE	Alu	AluJo
CAediting_809036	chr11_46737976_+	SINE	Alu	AluJo
CAediting_809037	chr11_46738053_+	SINE	Alu	AluSg
CAediting_809038	chr11_46738072_+	SINE	Alu	AluSg
CAediting_809039	chr11_46738104_+	SINE	Alu	AluSg
CAediting_809040	chr11_46738107_+	SINE	Alu	AluSg
CAediting_809041	chr11_46738108_+	SINE	Alu	AluSg
CAediting_809042	chr11_46738113_+	SINE	Alu	AluSg
CAediting_809043	chr11_46738118_+	SINE	Alu	AluSg
CAediting_809044	chr11_46738130_+	SINE	Alu	AluSg
CAediting_809045	chr11_46738140_+	SINE	Alu	AluSg
CAediting_809046	chr11_46738142_+	SINE	Alu	AluSg
CAediting_809047	chr11_46738166_+	SINE	Alu	AluSg
CAediting_809048	chr11_46738167_+	SINE	Alu	AluSg
CAediting_809049	chr11_46738175_+	SINE	Alu	AluSg
CAediting_809050	chr11_46738181_+	SINE	Alu	AluSg
CAediting_809051	chr11_46738184_+	SINE	Alu	AluSg
CAediting_809052	chr11_46738198_+	SINE	Alu	AluSg
CAediting_809053	chr11_46738210_+	SINE	Alu	AluSg
CAediting_809054	chr11_46738221_+	SINE	Alu	AluSg
CAediting_809055	chr11_46738222_+	SINE	Alu	AluSg
CAediting_809056	chr11_46738260_+	SINE	Alu	AluSg
CAediting_809057	chr11_46738261_+	SINE	Alu	AluSg
CAediting_809058	chr11_46738268_+	SINE	Alu	AluSg
CAediting_809059	chr11_46738273_+	SINE	Alu	AluSg
CAediting_809060	chr11_46738497_+	SINE	Alu	AluJb
CAediting_809061	chr11_46738505_+	SINE	Alu	AluJb
CAediting_809062	chr11_46738541_+	SINE	Alu	AluJb
CAediting_809063	chr11_46738548_+	SINE	Alu	AluJb
CAediting_809064	chr11_46738553_+	SINE	Alu	AluJb
CAediting_809065	chr11_46738559_+	SINE	Alu	AluJb
CAediting_809066	chr11_46738567_+	SINE	Alu	AluJb
CAediting_809067	chr11_46738574_+	SINE	Alu	AluJb
CAediting_809068	chr11_46738600_+	SINE	Alu	AluJb
CAediting_809069	chr11_46738603_+	SINE	Alu	AluJb
CAediting_809070	chr11_46738610_+	SINE	Alu	AluJb
CAediting_809071	chr11_46738615_+	SINE	Alu	AluJb
CAediting_809072	chr11_46738619_+	SINE	Alu	AluJb
CAediting_809073	chr11_46738653_+	SINE	Alu	AluJb
CAediting_809074	chr11_46738655_+	SINE	Alu	AluJb
CAediting_809075	chr11_46738666_+	SINE	Alu	AluJb
CAediting_809076	chr11_46738668_+	SINE	Alu	AluJb
CAediting_809077	chr11_46738675_+	SINE	Alu	AluJb

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RNA A-to-I editing events in the alternative splicing sites for F2

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000180210.13.F2.

Correlation between RNA A-to-I editing and PSI for ENSG00000180210.13.F2.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for F2

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

LIHC.CAediting_809051.ENSG00000180210.F2.png
Soverview

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Protein coding region RNA A-to-I editings for F2

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for F2

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for F2

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for F2

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LIHC	CAediting_809076	chr11_46738668_+	0.0312377404276185	0.206470574987831	.	.	.	.

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Relation with cancer stages for F2

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
LIHC	pathologic_stage	CAediting_809067	chr11_46738574_+	0.0472762294088163	0.239708395790909

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Relation with survival for F2

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
LIHC	CAediting_809076	chr11_46738668_+	0.00155634416537287	0.0217914	0.0100206

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RelatedDrugs for F2

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
F2	P00734	DB00001	Lepirudin	Prothrombin	BiotechDrug	approved
F2	P00734	DB01123	Proflavine	Prothrombin	SmallMoleculeDrug	approved
F2	P00734	DB06404	Human C1-esterase inhibitor	Prothrombin	BiotechDrug	approved
F2	P00734	DB06695	Dabigatran etexilate	Prothrombin	SmallMoleculeDrug	approved
F2	P00734	DB09332	Kappadione	Prothrombin	SmallMoleculeDrug	approved
F2	P00734	DB13152	Coagulation Factor IX Human	Prothrombin	BiotechDrug	approved
F2	P00734	DB14738	Turoctocog alfa pegol	Prothrombin	BiotechDrug	approved
F2	P00734	DB00006	Bivalirudin	Prothrombin	SmallMoleculeDrug	approved\|investigational
F2	P00734	DB00100	Coagulation Factor IX (Recombinant)	Prothrombin	BiotechDrug	approved\|investigational
F2	P00734	DB00278	Argatroban	Prothrombin	SmallMoleculeDrug	approved\|investigational
F2	P00734	DB01593	Zinc	Prothrombin	SmallMoleculeDrug	approved\|investigational
F2	P00734	DB05777	Thrombomodulin Alfa	Prothrombin	BiotechDrug	approved\|investigational
F2	P00734	DB09109	Turoctocog alfa	Prothrombin	BiotechDrug	approved\|investigational
F2	P00734	DB09130	Copper	Prothrombin	SmallMoleculeDrug	approved\|investigational
F2	P00734	DB09228	Conestat alfa	Prothrombin	BiotechDrug	approved\|investigational
F2	P00734	DB11166	Antithrombin Alfa	Prothrombin	BiotechDrug	approved\|investigational
F2	P00734	DB13151	Anti-inhibitor coagulant complex	Prothrombin	BiotechDrug	approved\|investigational
F2	P00734	DB14487	Zinc acetate	Prothrombin	SmallMoleculeDrug	approved\|investigational
F2	P00734	DB00055	Drotrecogin alfa	Prothrombin	BiotechDrug	approved\|investigational\|withdrawn
F2	P00734	DB04898	Ximelagatran	Prothrombin	SmallMoleculeDrug	approved\|investigational\|withdrawn
F2	P00734	DB00170	Menadione	Prothrombin	SmallMoleculeDrug	approved\|nutraceutical

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RelatedDiseases for F2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
F2	C0020640	Inherited Factor II deficiency	14	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
F2	C0040053	Thrombosis	4	CTD_human
F2	C0087086	Thrombus	4	CTD_human
F2	C0027051	Myocardial Infarction	3	CTD_human
F2	C0042487	Venous Thrombosis	3	CTD_human
F2	C0149871	Deep Vein Thrombosis	3	CTD_human
F2	C0007786	Brain Ischemia	2	CTD_human
F2	C0085762	Alcohol abuse	2	PSYGENET
F2	C0272317	Hereditary factor II deficiency disease	2	ORPHANET
F2	C0917798	Cerebral Ischemia	2	CTD_human
F2	C3203356	Factor II deficiency	2	ORPHANET
F2	C4722227	Hypoprothrombinemias	2	CTD_human;GENOMICS_ENGLAND
F2	C0002395	Alzheimer's Disease	1	CTD_human
F2	C0003873	Rheumatoid Arthritis	1	CTD_human
F2	C0005779	Blood Coagulation Disorders	1	CTD_human
F2	C0011265	Presenile dementia	1	CTD_human
F2	C0012739	Disseminated Intravascular Coagulation	1	CTD_human
F2	C0015695	Fatty Liver	1	CTD_human
F2	C0019080	Hemorrhage	1	CTD_human
F2	C0020564	Hypertrophy	1	CTD_human
F2	C0023890	Liver Cirrhosis	1	CTD_human
F2	C0027720	Nephrosis	1	CTD_human
F2	C0027746	Nerve Degeneration	1	CTD_human
F2	C0028754	Obesity	1	CTD_human
F2	C0030524	Paratuberculosis	1	CTD_human
F2	C0036341	Schizophrenia	1	CTD_human
F2	C0037198	Sinus Thrombosis, Intracranial	1	CTD_human
F2	C0038454	Cerebrovascular accident	1	CTD_human
F2	C0040038	Thromboembolism	1	CTD_human
F2	C0085605	Liver Failure	1	CTD_human
F2	C0162819	Skin Diseases, Vascular	1	CTD_human
F2	C0239946	Fibrosis, Liver	1	CTD_human
F2	C0267412	Mesenteric Venous Thrombosis	1	CTD_human
F2	C0276496	Familial Alzheimer Disease (FAD)	1	CTD_human
F2	C0398623	Thrombophilia	1	CTD_human
F2	C0400966	Non-alcoholic Fatty Liver Disease	1	CTD_human
F2	C0494463	Alzheimer Disease, Late Onset	1	CTD_human
F2	C0546126	Acute Confusional Senile Dementia	1	CTD_human
F2	C0750900	Alzheimer's Disease, Focal Onset	1	CTD_human
F2	C0750901	Alzheimer Disease, Early Onset	1	CTD_human
F2	C0751500	Petrous Sinus Thrombophlebitis	1	CTD_human
F2	C0751501	Intracranial Sinus Thrombophlebitis	1	CTD_human
F2	C0751502	Petrous Sinus Thrombosis	1	CTD_human
F2	C0751956	Acute Cerebrovascular Accidents	1	CTD_human
F2	C1412000	Mesenteric vascular insufficiency	1	CTD_human
F2	C1861172	Venous Thromboembolism	1	CTD_human
F2	C2239176	Liver carcinoma	1	CTD_human
F2	C2711227	Steatohepatitis	1	CTD_human
F2	C3241937	Nonalcoholic Steatohepatitis	1	CTD_human
F2	C3852984	Acute Mesenteric Arterial Embolus	1	CTD_human
F2	C3852985	Occlusive Mesenteric Arterial Ischemia	1	CTD_human
F2	C3852986	Nonocclusive Mesenteric Ischemia	1	CTD_human
F2	C3852987	Acute Mesenteric Arterial Thrombosis	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene