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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: ERCC3 (CAeditome ID:2071)

Gene summary for ERCC3

check button Gene summary
Gene informationGene symbol

ERCC3

Gene ID

2071

Gene nameERCC excision repair 3, TFIIH core complex helicase subunit
SynonymsBTF2|GTF2H|RAD25|Ssl2|TFIIH|TTD2|XPB
Cytomap

2q14.3

Type of geneprotein-coding
Descriptiongeneral transcription and DNA repair factor IIH helicase subunit XPBBTF2 p89DNA excision repair protein ERCC-3DNA repair helicaseDNA repair protein complementing XP-B cellsTFIIH 89 kDa subunitTFIIH basal transcription factor complex 89 kDa subunitT
Modification date20210518
UniProtAcc

P19447

Context- 33854616(Overexpression of ERCC3 is associated with poor prognosis in patients with pancreatic cancer)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
ERCC3

GO:0016887

General transcription and DNA repair factor IIH helicase subunit XPB

17466626

ERCC3

GO:0043138

General transcription and DNA repair factor IIH helicase subunit XPB

17466626

ERCC3

GO:0006283

General transcription and DNA repair factor IIH helicase subunit XPB

8663148

ERCC3

GO:0006366

General transcription and DNA repair factor IIH helicase subunit XPB

8692841

ERCC3

GO:0006366

General transcription and DNA repair factor IIH helicase subunit XPB

9852112

ERCC3

GO:0043065

General transcription and DNA repair factor IIH helicase subunit XPB

16914395

ERCC3

GO:0005654

General transcription and DNA repair factor IIH helicase subunit XPB

0000052

ERCC3

GO:0000439

General transcription and DNA repair factor IIH helicase subunit XPB

8692841

ERCC3

GO:0000439

General transcription and DNA repair factor IIH helicase subunit XPB

8692842

ERCC3

GO:0005669

General transcription and DNA repair factor IIH helicase subunit XPB

27193682

ERCC3

GO:0005675

General transcription and DNA repair factor IIH helicase subunit XPB

9852112


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RNA A-to-I events for ERCC3

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000163161.11

check button RNA A-to-I editing events in Cancer.
CAediting_210611(127262234, -), CAediting_210612(127262288, -), CAediting_210613(127262313, -), CAediting_210614(127262327, -), CAediting_210615(127262344, -), CAediting_210616(127262381, -), CAediting_210617(127262393, -), CAediting_210618(127262457, -), CAediting_210619(127262484, -), CAediting_210620(127263822, -), CAediting_210621(127263846, -), CAediting_210622(127263885, -), CAediting_210623(127263887, -), CAediting_210624(127263888, -), CAediting_210625(127264247, -), CAediting_210626(127264298, -), CAediting_210627(127264301, -), CAediting_210628(127264354, -), CAediting_210629(127264358, -), CAediting_210630(127264366, -), CAediting_210631(127264383, -), CAediting_210632(127264976, -), CAediting_210633(127264985, -), CAediting_210634(127265050, -), CAediting_210635(127265093, -), CAediting_210636(127265128, -), CAediting_210637(127265479, -), CAediting_210638(127265556, -), CAediting_210639(127265557, -), CAediting_210640(127265651, -), CAediting_210641(127265690, -), CAediting_210642(127266401, -), CAediting_210643(127266464, -), CAediting_210644(127266474, -), CAediting_210645(127266538, -), CAediting_210646(127266540, -), CAediting_210647(127266592, -), CAediting_210648(127266609, -), CAediting_210649(127266778, -), CAediting_210650(127266784, -), CAediting_210651(127266855, -), CAediting_210652(127266894, -), CAediting_210653(127267983, -), CAediting_210654(127268026, -), CAediting_210655(127268078, -), CAediting_210656(127268082, -), CAediting_210657(127268091, -), CAediting_210658(127268092, -), CAediting_210659(127268297, -), CAediting_210660(127268348, -), CAediting_210661(127268369, -), CAediting_210662(127268387, -), CAediting_210663(127268391, -), CAediting_210664(127268397, -), CAediting_210665(127268423, -), CAediting_210666(127268443, -), CAediting_210667(127268456, -), CAediting_210668(127268461, -), CAediting_210669(127268464, -), CAediting_210670(127268490, -), CAediting_210671(127268509, -), CAediting_210672(127269455, -), CAediting_210673(127269500, -), CAediting_210674(127269805, -), CAediting_210675(127269849, -), CAediting_210676(127269850, -), CAediting_210677(127269851, -), CAediting_210678(127269860, -), CAediting_210679(127269896, -), CAediting_210680(127269907, -), CAediting_210681(127269939, -), CAediting_210682(127269964, -), CAediting_210683(127269975, -), CAediting_210684(127269977, -), CAediting_210685(127270007, -), CAediting_210686(127270160, -), CAediting_210687(127270213, -), CAediting_210688(127270300, -), CAediting_210689(127272061, -), CAediting_210690(127272096, -), CAediting_210691(127272149, -), CAediting_210692(127272163, -), CAediting_210693(127272173, -), CAediting_210694(127277982, -), CAediting_210695(127284781, -), CAediting_210696(127290816, -), CAediting_210697(127290825, -), CAediting_210698(127290831, -), CAediting_210699(127290837, -), CAediting_210700(127290838, -), CAediting_210701(127290839, -), CAediting_210702(127290860, -), CAediting_210703(127290877, -), CAediting_210704(127290878, -), CAediting_210705(127290902, -), CAediting_210706(127290958, -), CAediting_210707(127290963, -), CAediting_210708(127290970, -), CAediting_210709(127290974, -), CAediting_210710(127290996, -), CAediting_210711(127291006, -), CAediting_210712(127291078, -), CAediting_210713(127291080, -), CAediting_210714(127291291, -), CAediting_210715(127291294, -), CAediting_210716(127291336, -), CAediting_210717(127291337, -), CAediting_210718(127291345, -), CAediting_210719(127291356, -), CAediting_210720(127291357, -), CAediting_210721(127291362, -), CAediting_210722(127291371, -), CAediting_210723(127291384, -), CAediting_210724(127291388, -), CAediting_210725(127291392, -), CAediting_210726(127291397, -), CAediting_210727(127291398, -), CAediting_210728(127291420, -), CAediting_210729(127291430, -), CAediting_210730(127291431, -), CAediting_210731(127291435, -), CAediting_210732(127291438, -), CAediting_210733(127291442, -), CAediting_210734(127291474, -), CAediting_210735(127291479, -), CAediting_210736(127291480, -), CAediting_210737(127291485, -), CAediting_210738(127291488, -), CAediting_210739(127291498, -), CAediting_210740(127291528, -), CAediting_210741(127291533, -), CAediting_210742(127291534, -), CAediting_210743(127291542, -), CAediting_210744(127291550, -), CAediting_210745(127291556, -),

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RNA editing positional annotations for ERCC3 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_210611chr2_127262234_-ncRNA_exonic
CAediting_210612chr2_127262288_-ncRNA_exonic
CAediting_210613chr2_127262313_-ncRNA_exonic
CAediting_210614chr2_127262327_-ncRNA_exonic
CAediting_210615chr2_127262344_-ncRNA_exonic
CAediting_210616chr2_127262381_-ncRNA_exonic
CAediting_210617chr2_127262393_-ncRNA_exonic
CAediting_210618chr2_127262457_-ncRNA_exonic
CAediting_210619chr2_127262484_-ncRNA_exonic
CAediting_210620chr2_127263822_-intronic
CAediting_210621chr2_127263846_-intronic
CAediting_210622chr2_127263885_-intronic
CAediting_210623chr2_127263887_-intronic
CAediting_210624chr2_127263888_-intronic
CAediting_210625chr2_127264247_-intronic
CAediting_210626chr2_127264298_-intronic
CAediting_210627chr2_127264301_-intronic
CAediting_210628chr2_127264354_-intronic
CAediting_210629chr2_127264358_-intronic
CAediting_210630chr2_127264366_-intronic
CAediting_210631chr2_127264383_-intronic
CAediting_210632chr2_127264976_-intronic
CAediting_210633chr2_127264985_-intronic
CAediting_210634chr2_127265050_-intronic
CAediting_210635chr2_127265093_-intronic
CAediting_210636chr2_127265128_-intronic
CAediting_210637chr2_127265479_-intronic
CAediting_210638chr2_127265556_-intronic
CAediting_210639chr2_127265557_-intronic
CAediting_210640chr2_127265651_-intronic
CAediting_210641chr2_127265690_-intronic
CAediting_210642chr2_127266401_-intronic
CAediting_210643chr2_127266464_-intronic
CAediting_210644chr2_127266474_-intronic
CAediting_210645chr2_127266538_-intronic
CAediting_210646chr2_127266540_-intronic
CAediting_210647chr2_127266592_-intronic
CAediting_210648chr2_127266609_-intronic
CAediting_210649chr2_127266778_-intronic
CAediting_210650chr2_127266784_-intronic
CAediting_210651chr2_127266855_-intronic
CAediting_210652chr2_127266894_-intronic
CAediting_210653chr2_127267983_-intronic
CAediting_210654chr2_127268026_-intronic
CAediting_210655chr2_127268078_-intronic
CAediting_210656chr2_127268082_-intronic
CAediting_210657chr2_127268091_-intronic
CAediting_210658chr2_127268092_-intronic
CAediting_210659chr2_127268297_-intronic
CAediting_210660chr2_127268348_-intronic
CAediting_210661chr2_127268369_-intronic
CAediting_210662chr2_127268387_-intronic
CAediting_210663chr2_127268391_-intronic
CAediting_210664chr2_127268397_-intronic
CAediting_210665chr2_127268423_-intronic
CAediting_210666chr2_127268443_-intronic
CAediting_210667chr2_127268456_-intronic
CAediting_210668chr2_127268461_-intronic
CAediting_210669chr2_127268464_-intronic
CAediting_210670chr2_127268490_-intronic
CAediting_210671chr2_127268509_-intronic
CAediting_210672chr2_127269455_-intronic
CAediting_210673chr2_127269500_-intronic
CAediting_210674chr2_127269805_-intronic
CAediting_210675chr2_127269849_-intronic
CAediting_210676chr2_127269850_-intronic
CAediting_210677chr2_127269851_-intronic
CAediting_210678chr2_127269860_-intronic
CAediting_210679chr2_127269896_-intronic
CAediting_210680chr2_127269907_-intronic
CAediting_210681chr2_127269939_-intronic
CAediting_210682chr2_127269964_-intronic
CAediting_210683chr2_127269975_-intronic
CAediting_210684chr2_127269977_-intronic
CAediting_210685chr2_127270007_-intronic
CAediting_210686chr2_127270160_-intronic
CAediting_210687chr2_127270213_-intronic
CAediting_210688chr2_127270300_-intronic
CAediting_210689chr2_127272061_-intronic
CAediting_210690chr2_127272096_-intronic
CAediting_210691chr2_127272149_-intronic
CAediting_210692chr2_127272163_-intronic
CAediting_210693chr2_127272173_-intronic
CAediting_210694chr2_127277982_-intronic
CAediting_210695chr2_127284781_-intronic
CAediting_210696chr2_127290816_-ncRNA_intronic
CAediting_210697chr2_127290825_-ncRNA_intronic
CAediting_210698chr2_127290831_-ncRNA_intronic
CAediting_210699chr2_127290837_-ncRNA_intronic
CAediting_210700chr2_127290838_-ncRNA_intronic
CAediting_210701chr2_127290839_-ncRNA_intronic
CAediting_210702chr2_127290860_-ncRNA_intronic
CAediting_210703chr2_127290877_-ncRNA_intronic
CAediting_210704chr2_127290878_-ncRNA_intronic
CAediting_210705chr2_127290902_-ncRNA_intronic
CAediting_210706chr2_127290958_-ncRNA_intronic
CAediting_210707chr2_127290963_-ncRNA_intronic
CAediting_210708chr2_127290970_-ncRNA_intronic
CAediting_210709chr2_127290974_-ncRNA_intronic
CAediting_210710chr2_127290996_-ncRNA_intronic
CAediting_210711chr2_127291006_-ncRNA_intronic
CAediting_210712chr2_127291078_-ncRNA_intronic
CAediting_210713chr2_127291080_-ncRNA_intronic
CAediting_210714chr2_127291291_-ncRNA_intronic
CAediting_210715chr2_127291294_-ncRNA_intronic
CAediting_210716chr2_127291336_-ncRNA_intronic
CAediting_210717chr2_127291337_-ncRNA_intronic
CAediting_210718chr2_127291345_-ncRNA_intronic
CAediting_210719chr2_127291356_-ncRNA_intronic
CAediting_210720chr2_127291357_-ncRNA_intronic
CAediting_210721chr2_127291362_-ncRNA_intronic
CAediting_210722chr2_127291371_-ncRNA_intronic
CAediting_210723chr2_127291384_-ncRNA_intronic
CAediting_210724chr2_127291388_-ncRNA_intronic
CAediting_210725chr2_127291392_-ncRNA_intronic
CAediting_210726chr2_127291397_-ncRNA_intronic
CAediting_210727chr2_127291398_-ncRNA_intronic
CAediting_210728chr2_127291420_-ncRNA_intronic
CAediting_210729chr2_127291430_-ncRNA_intronic
CAediting_210730chr2_127291431_-ncRNA_intronic
CAediting_210731chr2_127291435_-ncRNA_intronic
CAediting_210732chr2_127291438_-ncRNA_intronic
CAediting_210733chr2_127291442_-ncRNA_intronic
CAediting_210734chr2_127291474_-ncRNA_intronic
CAediting_210735chr2_127291479_-ncRNA_intronic
CAediting_210736chr2_127291480_-ncRNA_intronic
CAediting_210737chr2_127291485_-ncRNA_intronic
CAediting_210738chr2_127291488_-ncRNA_intronic
CAediting_210739chr2_127291498_-ncRNA_intronic
CAediting_210740chr2_127291528_-ncRNA_intronic
CAediting_210741chr2_127291533_-ncRNA_intronic
CAediting_210742chr2_127291534_-ncRNA_intronic
CAediting_210743chr2_127291542_-ncRNA_intronic
CAediting_210744chr2_127291550_-ncRNA_intronic
CAediting_210745chr2_127291556_-ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_210611chr2_127262234_-SINEAluAluSz
CAediting_210612chr2_127262288_-SINEAluAluSz
CAediting_210613chr2_127262313_-SINEAluAluSz
CAediting_210614chr2_127262327_-SINEAluAluSz
CAediting_210615chr2_127262344_-SINEAluAluSz
CAediting_210616chr2_127262381_-SINEAluAluSz
CAediting_210617chr2_127262393_-SINEAluAluSz
CAediting_210618chr2_127262457_-SINEAluAluSz
CAediting_210619chr2_127262484_-SINEAluAluSz
CAediting_210620chr2_127263822_-SINEAluAluY
CAediting_210621chr2_127263846_-SINEAluAluY
CAediting_210622chr2_127263885_-SINEAluAluY
CAediting_210623chr2_127263887_-SINEAluAluY
CAediting_210624chr2_127263888_-SINEAluAluY
CAediting_210625chr2_127264247_-SINEAluAluSq2
CAediting_210626chr2_127264298_-SINEAluAluSq2
CAediting_210627chr2_127264301_-SINEAluAluSq2
CAediting_210628chr2_127264354_-SINEAluAluSq2
CAediting_210629chr2_127264358_-SINEAluAluSq2
CAediting_210630chr2_127264366_-SINEAluAluSq2
CAediting_210631chr2_127264383_-SINEAluAluSq2
CAediting_210632chr2_127264976_-SINEAluAluSx
CAediting_210633chr2_127264985_-SINEAluAluSx
CAediting_210634chr2_127265050_-SINEAluAluSx
CAediting_210635chr2_127265093_-SINEAluAluSx
CAediting_210636chr2_127265128_-SINEAluAluSx
CAediting_210637chr2_127265479_-SINEAluAluSg
CAediting_210638chr2_127265556_-SINEAluAluSg
CAediting_210639chr2_127265557_-SINEAluAluSg
CAediting_210640chr2_127265651_-SINEAluAluSg
CAediting_210641chr2_127265690_-SINEAluAluSg
CAediting_210642chr2_127266401_-SINEAluAluY
CAediting_210643chr2_127266464_-SINEAluAluY
CAediting_210644chr2_127266474_-SINEAluAluY
CAediting_210645chr2_127266538_-SINEAluAluY
CAediting_210646chr2_127266540_-SINEAluAluY
CAediting_210647chr2_127266592_-SINEAluAluY
CAediting_210648chr2_127266609_-SINEAluAluY
CAediting_210649chr2_127266778_-SINEAluAluSx
CAediting_210650chr2_127266784_-SINEAluAluSx
CAediting_210651chr2_127266855_-SINEAluAluSx
CAediting_210652chr2_127266894_-SINEAluAluSx
CAediting_210653chr2_127267983_-SINEAluAluSq2
CAediting_210654chr2_127268026_-SINEAluAluSq2
CAediting_210655chr2_127268078_-SINEAluAluSq2
CAediting_210656chr2_127268082_-SINEAluAluSq2
CAediting_210657chr2_127268091_-SINEAluAluSq2
CAediting_210658chr2_127268092_-SINEAluAluSq2
CAediting_210659chr2_127268297_-SINEAluAluJb
CAediting_210660chr2_127268348_-SINEAluAluJb
CAediting_210661chr2_127268369_-SINEAluAluJb
CAediting_210662chr2_127268387_-SINEAluAluJb
CAediting_210663chr2_127268391_-SINEAluAluJb
CAediting_210664chr2_127268397_-SINEAluAluJb
CAediting_210665chr2_127268423_-SINEAluAluJb
CAediting_210666chr2_127268443_-SINEAluAluJb
CAediting_210667chr2_127268456_-SINEAluAluJb
CAediting_210668chr2_127268461_-SINEAluAluJb
CAediting_210669chr2_127268464_-SINEAluAluJb
CAediting_210670chr2_127268490_-SINEAluAluJb
CAediting_210671chr2_127268509_-SINEAluAluJb
CAediting_210672chr2_127269455_-SINEAluAluY
CAediting_210673chr2_127269500_-SINEAluAluY
CAediting_210674chr2_127269805_-SINEAluAluSx3
CAediting_210675chr2_127269849_-SINEAluAluSx3
CAediting_210676chr2_127269850_-SINEAluAluSx3
CAediting_210677chr2_127269851_-SINEAluAluSx3
CAediting_210678chr2_127269860_-SINEAluAluSx3
CAediting_210679chr2_127269896_-SINEAluAluSx3
CAediting_210680chr2_127269907_-SINEAluAluSx3
CAediting_210681chr2_127269939_-SINEAluAluSx3
CAediting_210682chr2_127269964_-SINEAluAluSx3
CAediting_210683chr2_127269975_-SINEAluAluSx3
CAediting_210684chr2_127269977_-SINEAluAluSx3
CAediting_210685chr2_127270007_-SINEAluAluSx3
CAediting_210686chr2_127270160_-SINEAluAluJo
CAediting_210687chr2_127270213_-SINEAluAluJo
CAediting_210688chr2_127270300_-SINEAluAluJo
CAediting_210689chr2_127272061_-SINEAluAluSq2
CAediting_210690chr2_127272096_-SINEAluAluSq2
CAediting_210691chr2_127272149_-SINEAluAluSq2
CAediting_210692chr2_127272163_-SINEAluAluSq2
CAediting_210693chr2_127272173_-SINEAluAluSq2
CAediting_210694chr2_127277982_-SINEAluAluJb
CAediting_210695chr2_127284781_-SINEAluAluJb
CAediting_210696chr2_127290816_-SINEAluAluSx1
CAediting_210697chr2_127290825_-SINEAluAluSx1
CAediting_210698chr2_127290831_-SINEAluAluSx1
CAediting_210699chr2_127290837_-SINEAluAluSx1
CAediting_210700chr2_127290838_-SINEAluAluSx1
CAediting_210701chr2_127290839_-SINEAluAluSx1
CAediting_210702chr2_127290860_-SINEAluAluSx1
CAediting_210703chr2_127290877_-SINEAluAluSx1
CAediting_210704chr2_127290878_-SINEAluAluSx1
CAediting_210705chr2_127290902_-SINEAluAluSx1
CAediting_210706chr2_127290958_-SINEAluAluSx1
CAediting_210707chr2_127290963_-SINEAluAluSx1
CAediting_210708chr2_127290970_-SINEAluAluSx1
CAediting_210709chr2_127290974_-SINEAluAluSx1
CAediting_210710chr2_127290996_-SINEAluAluSx1
CAediting_210711chr2_127291006_-SINEAluAluSx1
CAediting_210712chr2_127291078_-SINEAluAluSx1
CAediting_210713chr2_127291080_-SINEAluAluSx1
CAediting_210714chr2_127291291_-SINEAluAluSx1
CAediting_210715chr2_127291294_-SINEAluAluSx1
CAediting_210716chr2_127291336_-SINEAluAluSx1
CAediting_210717chr2_127291337_-SINEAluAluSx1
CAediting_210718chr2_127291345_-SINEAluAluSx1
CAediting_210719chr2_127291356_-SINEAluAluSx1
CAediting_210720chr2_127291357_-SINEAluAluSx1
CAediting_210721chr2_127291362_-SINEAluAluSx1
CAediting_210722chr2_127291371_-SINEAluAluSx1
CAediting_210723chr2_127291384_-SINEAluAluSx1
CAediting_210724chr2_127291388_-SINEAluAluSx1
CAediting_210725chr2_127291392_-SINEAluAluSx1
CAediting_210726chr2_127291397_-SINEAluAluSx1
CAediting_210727chr2_127291398_-SINEAluAluSx1
CAediting_210728chr2_127291420_-SINEAluAluSx1
CAediting_210729chr2_127291430_-SINEAluAluSx1
CAediting_210730chr2_127291431_-SINEAluAluSx1
CAediting_210731chr2_127291435_-SINEAluAluSx1
CAediting_210732chr2_127291438_-SINEAluAluSx1
CAediting_210733chr2_127291442_-SINEAluAluSx1
CAediting_210734chr2_127291474_-SINEAluAluSx1
CAediting_210735chr2_127291479_-SINEAluAluSx1
CAediting_210736chr2_127291480_-SINEAluAluSx1
CAediting_210737chr2_127291485_-SINEAluAluSx1
CAediting_210738chr2_127291488_-SINEAluAluSx1
CAediting_210739chr2_127291498_-SINEAluAluSx1
CAediting_210740chr2_127291528_-SINEAluAluSx1
CAediting_210741chr2_127291533_-SINEAluAluSx1
CAediting_210742chr2_127291534_-SINEAluAluSx1
CAediting_210743chr2_127291542_-SINEAluAluSx1
CAediting_210744chr2_127291550_-SINEAluAluSx1
CAediting_210745chr2_127291556_-SINEAluAluSx1

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RNA A-to-I editing events in the alternative splicing sites for ERCC3

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000163161.11.ERCC3.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000163161.11.ERCC3.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ERCC3

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
LGG.CAediting_210708.ENSG00000163161.ERCC3.png
Soverview

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Protein coding region RNA A-to-I editings for ERCC3

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ERCC3

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1306324chr19_13836464_-ENSG00000163161.11ENST00000426778hsa-miR-27a-3p1272805691272805757mer-m8127280568127280590148-16.92
CAediting_1306324chr19_13836464_-ENSG00000163161.11ENST00000445889hsa-miR-27a-3p1272805691272805757mer-m8127280568127280590148-16.92
CAediting_1054808chr15_66496985_-ENSG00000163161.11ENST00000426778hsa-miR-45121272935211272935277mer-m8127293520127293541144-19.03
CAediting_1229414chr17_67471546_+ENSG00000163161.11ENST00000426778hsa-miR-548aa1272902361272902427mer-m8127290235127290259170-16.61
CAediting_414656chr5_72878640_+ENSG00000163161.11ENST00000426778hsa-miR-4804-3p1272902431272902497mer-m8127290242127290262158-12.34
CAediting_228905chr2_188297554_+ENSG00000163161.11ENST00000426778hsa-miR-561-3p1272897401272897467mer-m8127289739127289767142-16.59
CAediting_414656chr5_72878640_+ENSG00000163161.11ENST00000426778hsa-miR-4804-3p1272893381272893458mer-1a127289338127289358144-12.52
CAediting_1160181chr17_7017644_-ENSG00000163161.11ENST00000426778hsa-miR-195-3p1272887611272887688mer-1a127288761127288781148-10.85
CAediting_1054808chr15_66496985_-ENSG00000163161.11ENST00000445889hsa-miR-45121272935211272935277mer-m8127293520127293541144-19.03
CAediting_1229414chr17_67471546_+ENSG00000163161.11ENST00000445889hsa-miR-548aa1272902361272902427mer-m8127290235127290259170-16.61
CAediting_414656chr5_72878640_+ENSG00000163161.11ENST00000445889hsa-miR-4804-3p1272902431272902497mer-m8127290242127290262158-12.34
CAediting_228905chr2_188297554_+ENSG00000163161.11ENST00000445889hsa-miR-561-3p1272897401272897467mer-m8127289739127289767142-16.59
CAediting_414656chr5_72878640_+ENSG00000163161.11ENST00000445889hsa-miR-4804-3p1272893381272893458mer-1a127289338127289358144-12.52
CAediting_1160181chr17_7017644_-ENSG00000163161.11ENST00000445889hsa-miR-195-3p1272887611272887688mer-1a127288761127288781148-10.85

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ERCC3

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000491292.4retained_intronSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_210611ENST00000491292.4chr2_127262234_--1299.00-1298.50-1310.30
CAediting_210612ENST00000491292.4chr2_127262288_--1299.90-1298.50-1310.30
CAediting_210613ENST00000491292.4chr2_127262313_--1298.50-1298.50-1310.30
CAediting_210614ENST00000491292.4chr2_127262327_--1298.40-1298.50-1310.30
CAediting_210615ENST00000491292.4chr2_127262344_--1296.30-1298.50-1310.30
CAediting_210616ENST00000491292.4chr2_127262381_--1302.70-1298.50-1310.30
CAediting_210617ENST00000491292.4chr2_127262393_--1298.90-1298.50-1310.30
CAediting_210618ENST00000491292.4chr2_127262457_--1301.60-1298.50-1310.30
CAediting_210619ENST00000491292.4chr2_127262484_--1301.80-1298.50-1310.30

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Relation with ADAR for ERCC3

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for ERCC3

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for ERCC3

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for ERCC3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ERCC3

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
ERCC3C0268136Xeroderma pigmentosum, group B8CLINGEN;CTD_human;GENOMICS_ENGLAND;UNIPROT
ERCC3C0274861Arsenic Poisoning, Inorganic1CTD_human
ERCC3C0274862Nervous System, Organic Arsenic Poisoning1CTD_human
ERCC3C0311375Arsenic Poisoning1CTD_human
ERCC3C0751851Arsenic Encephalopathy1CTD_human
ERCC3C0751852Arsenic Induced Polyneuropathy1CTD_human
ERCC3C1866504Photosensitive Trichothiodystrophy1GENOMICS_ENGLAND
ERCC3C1955934Trichothiodystrophy Syndromes1GENOMICS_ENGLAND;ORPHANET
ERCC3C4225344TRICHOTHIODYSTROPHY 2, PHOTOSENSITIVE1CTD_human;GENOMICS_ENGLAND;UNIPROT
ERCC3C4721453Peripheral Nervous System Diseases1CTD_human