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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: ERBB3 (CAeditome ID:2065)

Gene summary for ERBB3

check button Gene summary
Gene informationGene symbol

ERBB3

Gene ID

2065

Gene nameerb-b2 receptor tyrosine kinase 3
SynonymsErbB-3|FERLK|HER3|LCCS2|MDA-BF-1|c-erbB-3|c-erbB3|erbB3-S|p180-ErbB3|p45-sErbB3|p85-sErbB3
Cytomap

12q13.2

Type of geneprotein-coding
Descriptionreceptor tyrosine-protein kinase erbB-3human epidermal growth factor receptor 3proto-oncogene-like protein c-ErbB-3tyrosine kinase-type cell surface receptor HER3v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
Modification date20210518
UniProtAcc

P21860

Context- 30831376(ErbB3 ligand, Heregulin1, is a Major Mitogenic Factor for Uncontrolled Lung Cancer Cell Proliferation)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
ERBB3

GO:0004713

Receptor tyrosine-protein kinase erbB-3

7556068

ERBB3

GO:0030296

Receptor tyrosine-protein kinase erbB-3

7556068

ERBB3

GO:0038132

Receptor tyrosine-protein kinase erbB-3

20682778

ERBB3

GO:0007162

Receptor tyrosine-protein kinase erbB-3

7556068

ERBB3

GO:0007165

Receptor tyrosine-protein kinase erbB-3

10572067

ERBB3

GO:0009968

Receptor tyrosine-protein kinase erbB-3

11389077

ERBB3

GO:0014065

Receptor tyrosine-protein kinase erbB-3

7556068

ERBB3

GO:0042127

Receptor tyrosine-protein kinase erbB-3

11389077

ERBB3

GO:0051048

Receptor tyrosine-protein kinase erbB-3

10559227

ERBB3

GO:0005615

Receptor tyrosine-protein kinase erbB-3

11389077

ERBB3

GO:0016323

Receptor tyrosine-protein kinase erbB-3

12646923

ERBB3

GO:0038143

Receptor tyrosine-protein kinase erbB-3

12000754

ERBB3

GO:0043235

Receptor tyrosine-protein kinase erbB-3

23382219


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RNA A-to-I events for ERBB3

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000065361.13

check button RNA A-to-I editing events in Cancer.
CAediting_895880(56085481, +), CAediting_895881(56085483, +), CAediting_895882(56085489, +), CAediting_895883(56085490, +), CAediting_895884(56085511, +), CAediting_895885(56085515, +), CAediting_895886(56085520, +), CAediting_895887(56085532, +), CAediting_895888(56085535, +), CAediting_895889(56085546, +), CAediting_895890(56085569, +), CAediting_895891(56087018, +), CAediting_895892(56087072, +), CAediting_895893(56089153, +), CAediting_895894(56089157, +), CAediting_895895(56089184, +), CAediting_895896(56089189, +), CAediting_895897(56089208, +), CAediting_895898(56089213, +), CAediting_895899(56089234, +), CAediting_895900(56089243, +), CAediting_895901(56089244, +), CAediting_895902(56089247, +), CAediting_895903(56089263, +), CAediting_895904(56089267, +), CAediting_895905(56089275, +), CAediting_895906(56089283, +), CAediting_895907(56089294, +), CAediting_895908(56089304, +), CAediting_895909(56089359, +), CAediting_895910(56089493, +), CAediting_895911(56089528, +), CAediting_895912(56089578, +), CAediting_895913(56089581, +), CAediting_895914(56089582, +), CAediting_895915(56089583, +), CAediting_895916(56089590, +), CAediting_895917(56089591, +), CAediting_895918(56089592, +), CAediting_895919(56089593, +), CAediting_895920(56089596, +), CAediting_895921(56089624, +), CAediting_895922(56089625, +), CAediting_895923(56089630, +), CAediting_895924(56089634, +), CAediting_895925(56089638, +), CAediting_895926(56089647, +), CAediting_895927(56089660, +), CAediting_895928(56089665, +), CAediting_895929(56089666, +), CAediting_895930(56089680, +), CAediting_895931(56089681, +), CAediting_895932(56089690, +), CAediting_895933(56089695, +), CAediting_895934(56089697, +), CAediting_895935(56089702, +), CAediting_895936(56089710, +), CAediting_895937(56089715, +), CAediting_895938(56089726, +), CAediting_895939(56089732, +), CAediting_895940(56089747, +), CAediting_895941(56089749, +), CAediting_895942(56089750, +), CAediting_895943(56089759, +), CAediting_895944(56090022, +), CAediting_895945(56090039, +), CAediting_895946(56090041, +), CAediting_895947(56090054, +), CAediting_895948(56090055, +), CAediting_895949(56090100, +), CAediting_895950(56090103, +), CAediting_895951(56090129, +), CAediting_895952(56090165, +), CAediting_895953(56090180, +), CAediting_895954(56090183, +), CAediting_895955(56090197, +), CAediting_895956(56090204, +), CAediting_895957(56090252, +), CAediting_895958(56090261, +), CAediting_895959(56090262, +), CAediting_895960(56090276, +), CAediting_895961(56090277, +), CAediting_895962(56090382, +), CAediting_895963(56090434, +), CAediting_895964(56090437, +), CAediting_895965(56090479, +), CAediting_895966(56090523, +), CAediting_895967(56090529, +), CAediting_895968(56090533, +), CAediting_895969(56090537, +), CAediting_895970(56090550, +), CAediting_895971(56090558, +), CAediting_895972(56090564, +), CAediting_895973(56090565, +), CAediting_895974(56090576, +), CAediting_895975(56090594, +), CAediting_895976(56090614, +), CAediting_895977(56091126, +), CAediting_895978(56091138, +), CAediting_895979(56091153, +), CAediting_895980(56091155, +), CAediting_895981(56091171, +), CAediting_895982(56091176, +), CAediting_895983(56091181, +), CAediting_895984(56091182, +), CAediting_895985(56091214, +), CAediting_895986(56091226, +), CAediting_895987(56091236, +), CAediting_895988(56091238, +), CAediting_895989(56091984, +), CAediting_895990(56092013, +), CAediting_895991(56092019, +), CAediting_895992(56092023, +), CAediting_895993(56092134, +), CAediting_895994(56092186, +), CAediting_895995(56092232, +), CAediting_895996(56092242, +), CAediting_895997(56092268, +), CAediting_895998(56092282, +), CAediting_895999(56092286, +), CAediting_896000(56092291, +), CAediting_896001(56092304, +), CAediting_896002(56092309, +), CAediting_896003(56092310, +), CAediting_896004(56092314, +), CAediting_896005(56092330, +), CAediting_896006(56092334, +), CAediting_896007(56092339, +), CAediting_896008(56092372, +), CAediting_896009(56094719, +), CAediting_896010(56098337, +), CAediting_896011(56099128, +), CAediting_896012(56099230, +), CAediting_896013(56099378, +), CAediting_896014(56099420, +), CAediting_896015(56099479, +), CAediting_896016(56099508, +), CAediting_896017(56099542, +), CAediting_896018(56099561, +), CAediting_896019(56100587, +), CAediting_896020(56100599, +), CAediting_896021(56100762, +), CAediting_896022(56100852, +), CAediting_896023(56100889, +), CAediting_896024(56102770, +), CAediting_896025(56102787, +), CAediting_896026(56102793, +),

Top

RNA editing positional annotations for ERBB3 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_895880chr12_56085481_+ncRNA_intronic
CAediting_895881chr12_56085483_+ncRNA_intronic
CAediting_895882chr12_56085489_+ncRNA_intronic
CAediting_895883chr12_56085490_+ncRNA_intronic
CAediting_895884chr12_56085511_+ncRNA_intronic
CAediting_895885chr12_56085515_+ncRNA_intronic
CAediting_895886chr12_56085520_+ncRNA_intronic
CAediting_895887chr12_56085532_+ncRNA_intronic
CAediting_895888chr12_56085535_+ncRNA_intronic
CAediting_895889chr12_56085546_+ncRNA_intronic
CAediting_895890chr12_56085569_+ncRNA_intronic
CAediting_895891chr12_56087018_+ncRNA_intronic
CAediting_895892chr12_56087072_+ncRNA_intronic
CAediting_895893chr12_56089153_+intronic
CAediting_895894chr12_56089157_+intronic
CAediting_895895chr12_56089184_+intronic
CAediting_895896chr12_56089189_+intronic
CAediting_895897chr12_56089208_+intronic
CAediting_895898chr12_56089213_+intronic
CAediting_895899chr12_56089234_+intronic
CAediting_895900chr12_56089243_+intronic
CAediting_895901chr12_56089244_+intronic
CAediting_895902chr12_56089247_+intronic
CAediting_895903chr12_56089263_+intronic
CAediting_895904chr12_56089267_+intronic
CAediting_895905chr12_56089275_+intronic
CAediting_895906chr12_56089283_+intronic
CAediting_895907chr12_56089294_+intronic
CAediting_895908chr12_56089304_+intronic
CAediting_895909chr12_56089359_+intronic
CAediting_895910chr12_56089493_+intronic
CAediting_895911chr12_56089528_+intronic
CAediting_895912chr12_56089578_+intronic
CAediting_895913chr12_56089581_+intronic
CAediting_895914chr12_56089582_+intronic
CAediting_895915chr12_56089583_+intronic
CAediting_895916chr12_56089590_+intronic
CAediting_895917chr12_56089591_+intronic
CAediting_895918chr12_56089592_+intronic
CAediting_895919chr12_56089593_+intronic
CAediting_895920chr12_56089596_+intronic
CAediting_895921chr12_56089624_+intronic
CAediting_895922chr12_56089625_+intronic
CAediting_895923chr12_56089630_+intronic
CAediting_895924chr12_56089634_+intronic
CAediting_895925chr12_56089638_+intronic
CAediting_895926chr12_56089647_+intronic
CAediting_895927chr12_56089660_+intronic
CAediting_895928chr12_56089665_+intronic
CAediting_895929chr12_56089666_+intronic
CAediting_895930chr12_56089680_+intronic
CAediting_895931chr12_56089681_+intronic
CAediting_895932chr12_56089690_+intronic
CAediting_895933chr12_56089695_+intronic
CAediting_895934chr12_56089697_+intronic
CAediting_895935chr12_56089702_+intronic
CAediting_895936chr12_56089710_+intronic
CAediting_895937chr12_56089715_+intronic
CAediting_895938chr12_56089726_+intronic
CAediting_895939chr12_56089732_+intronic
CAediting_895940chr12_56089747_+intronic
CAediting_895941chr12_56089749_+intronic
CAediting_895942chr12_56089750_+intronic
CAediting_895943chr12_56089759_+intronic
CAediting_895944chr12_56090022_+intronic
CAediting_895945chr12_56090039_+intronic
CAediting_895946chr12_56090041_+intronic
CAediting_895947chr12_56090054_+intronic
CAediting_895948chr12_56090055_+intronic
CAediting_895949chr12_56090100_+intronic
CAediting_895950chr12_56090103_+intronic
CAediting_895951chr12_56090129_+intronic
CAediting_895952chr12_56090165_+intronic
CAediting_895953chr12_56090180_+intronic
CAediting_895954chr12_56090183_+intronic
CAediting_895955chr12_56090197_+intronic
CAediting_895956chr12_56090204_+intronic
CAediting_895957chr12_56090252_+intronic
CAediting_895958chr12_56090261_+intronic
CAediting_895959chr12_56090262_+intronic
CAediting_895960chr12_56090276_+intronic
CAediting_895961chr12_56090277_+intronic
CAediting_895962chr12_56090382_+intronic
CAediting_895963chr12_56090434_+intronic
CAediting_895964chr12_56090437_+intronic
CAediting_895965chr12_56090479_+intronic
CAediting_895966chr12_56090523_+intronic
CAediting_895967chr12_56090529_+intronic
CAediting_895968chr12_56090533_+intronic
CAediting_895969chr12_56090537_+intronic
CAediting_895970chr12_56090550_+intronic
CAediting_895971chr12_56090558_+intronic
CAediting_895972chr12_56090564_+intronic
CAediting_895973chr12_56090565_+intronic
CAediting_895974chr12_56090576_+intronic
CAediting_895975chr12_56090594_+intronic
CAediting_895976chr12_56090614_+intronic
CAediting_895977chr12_56091126_+intronic
CAediting_895978chr12_56091138_+intronic
CAediting_895979chr12_56091153_+intronic
CAediting_895980chr12_56091155_+intronic
CAediting_895981chr12_56091171_+intronic
CAediting_895982chr12_56091176_+intronic
CAediting_895983chr12_56091181_+intronic
CAediting_895984chr12_56091182_+intronic
CAediting_895985chr12_56091214_+intronic
CAediting_895986chr12_56091226_+intronic
CAediting_895987chr12_56091236_+intronic
CAediting_895988chr12_56091238_+intronic
CAediting_895989chr12_56091984_+intronic
CAediting_895990chr12_56092013_+intronic
CAediting_895991chr12_56092019_+intronic
CAediting_895992chr12_56092023_+intronic
CAediting_895993chr12_56092134_+intronic
CAediting_895994chr12_56092186_+intronic
CAediting_895995chr12_56092232_+intronic
CAediting_895996chr12_56092242_+intronic
CAediting_895997chr12_56092268_+intronic
CAediting_895998chr12_56092282_+intronic
CAediting_895999chr12_56092286_+intronic
CAediting_896000chr12_56092291_+intronic
CAediting_896001chr12_56092304_+intronic
CAediting_896002chr12_56092309_+intronic
CAediting_896003chr12_56092310_+intronic
CAediting_896004chr12_56092314_+intronic
CAediting_896005chr12_56092330_+intronic
CAediting_896006chr12_56092334_+intronic
CAediting_896007chr12_56092339_+intronic
CAediting_896008chr12_56092372_+intronic
CAediting_896009chr12_56094719_+ncRNA_intronic
CAediting_896010chr12_56098337_+ncRNA_intronic
CAediting_896011chr12_56099128_+intronic
CAediting_896012chr12_56099230_+intronic
CAediting_896013chr12_56099378_+intronic
CAediting_896014chr12_56099420_+intronic
CAediting_896015chr12_56099479_+intronic
CAediting_896016chr12_56099508_+intronic
CAediting_896017chr12_56099542_+intronic
CAediting_896018chr12_56099561_+intronic
CAediting_896019chr12_56100587_+intronic
CAediting_896020chr12_56100599_+intronic
CAediting_896021chr12_56100762_+intronic
CAediting_896022chr12_56100852_+intronic
CAediting_896023chr12_56100889_+intronic
CAediting_896024chr12_56102770_+UTR3
CAediting_896025chr12_56102787_+UTR3
CAediting_896026chr12_56102793_+UTR3

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_895880chr12_56085481_+SINEAluAluSz
CAediting_895881chr12_56085483_+SINEAluAluSz
CAediting_895882chr12_56085489_+SINEAluAluSz
CAediting_895883chr12_56085490_+SINEAluAluSz
CAediting_895884chr12_56085511_+SINEAluAluSz
CAediting_895885chr12_56085515_+SINEAluAluSz
CAediting_895886chr12_56085520_+SINEAluAluSz
CAediting_895887chr12_56085532_+SINEAluAluSz
CAediting_895888chr12_56085535_+SINEAluAluSz
CAediting_895889chr12_56085546_+SINEAluAluSz
CAediting_895890chr12_56085569_+SINEAluAluSz
CAediting_895891chr12_56087018_+SINEAluAluJo
CAediting_895892chr12_56087072_+SINEAluAluJo
CAediting_895893chr12_56089153_+SINEAluAluJo
CAediting_895894chr12_56089157_+SINEAluAluJo
CAediting_895895chr12_56089184_+SINEAluAluJo
CAediting_895896chr12_56089189_+SINEAluAluJo
CAediting_895897chr12_56089208_+SINEAluAluJo
CAediting_895898chr12_56089213_+SINEAluAluJo
CAediting_895899chr12_56089234_+SINEAluAluJo
CAediting_895900chr12_56089243_+SINEAluAluJo
CAediting_895901chr12_56089244_+SINEAluAluJo
CAediting_895902chr12_56089247_+SINEAluAluJo
CAediting_895903chr12_56089263_+SINEAluAluJo
CAediting_895904chr12_56089267_+SINEAluAluJo
CAediting_895905chr12_56089275_+SINEAluAluJo
CAediting_895906chr12_56089283_+SINEAluAluJo
CAediting_895907chr12_56089294_+SINEAluAluJo
CAediting_895908chr12_56089304_+SINEAluAluJo
CAediting_895909chr12_56089359_+SINEAluAluJo
CAediting_895910chr12_56089493_+SINEAluAluSc
CAediting_895911chr12_56089528_+SINEAluAluSc
CAediting_895912chr12_56089578_+SINEAluAluSc
CAediting_895913chr12_56089581_+SINEAluAluSc
CAediting_895914chr12_56089582_+SINEAluAluSc
CAediting_895915chr12_56089583_+SINEAluAluSc
CAediting_895916chr12_56089590_+SINEAluAluSc
CAediting_895917chr12_56089591_+SINEAluAluSc
CAediting_895918chr12_56089592_+SINEAluAluSc
CAediting_895919chr12_56089593_+SINEAluAluSc
CAediting_895920chr12_56089596_+SINEAluAluSc
CAediting_895921chr12_56089624_+SINEAluAluSc
CAediting_895922chr12_56089625_+SINEAluAluSc
CAediting_895923chr12_56089630_+SINEAluAluSc
CAediting_895924chr12_56089634_+SINEAluAluSc
CAediting_895925chr12_56089638_+SINEAluAluSc
CAediting_895926chr12_56089647_+SINEAluAluSc
CAediting_895927chr12_56089660_+SINEAluAluSc
CAediting_895928chr12_56089665_+SINEAluAluSc
CAediting_895929chr12_56089666_+SINEAluAluSc
CAediting_895930chr12_56089680_+SINEAluAluSc
CAediting_895931chr12_56089681_+SINEAluAluSc
CAediting_895932chr12_56089690_+SINEAluAluSc
CAediting_895933chr12_56089695_+SINEAluAluSc
CAediting_895934chr12_56089697_+SINEAluAluSc
CAediting_895935chr12_56089702_+SINEAluAluSc
CAediting_895936chr12_56089710_+SINEAluAluSc
CAediting_895937chr12_56089715_+SINEAluAluSc
CAediting_895938chr12_56089726_+SINEAluAluSc
CAediting_895939chr12_56089732_+SINEAluAluSc
CAediting_895940chr12_56089747_+SINEAluAluSc
CAediting_895941chr12_56089749_+SINEAluAluSc
CAediting_895942chr12_56089750_+SINEAluAluSc
CAediting_895943chr12_56089759_+SINEAluAluSc
CAediting_895944chr12_56090022_+SINEAluAluSz
CAediting_895945chr12_56090039_+SINEAluAluSz
CAediting_895946chr12_56090041_+SINEAluAluSz
CAediting_895947chr12_56090054_+SINEAluAluSz
CAediting_895948chr12_56090055_+SINEAluAluSz
CAediting_895949chr12_56090100_+SINEAluAluSz
CAediting_895950chr12_56090103_+SINEAluAluSz
CAediting_895951chr12_56090129_+SINEAluAluSz
CAediting_895952chr12_56090165_+SINEAluAluSz
CAediting_895953chr12_56090180_+SINEAluAluSz
CAediting_895954chr12_56090183_+SINEAluAluSz
CAediting_895955chr12_56090197_+SINEAluAluSz
CAediting_895956chr12_56090204_+SINEAluAluSz
CAediting_895957chr12_56090252_+SINEAluAluSz
CAediting_895958chr12_56090261_+SINEAluAluSz
CAediting_895959chr12_56090262_+SINEAluAluSz
CAediting_895960chr12_56090276_+SINEAluAluSz
CAediting_895961chr12_56090277_+SINEAluAluSz
CAediting_895962chr12_56090382_+SINEAluAluSc
CAediting_895963chr12_56090434_+SINEAluAluSc
CAediting_895964chr12_56090437_+SINEAluAluSc
CAediting_895965chr12_56090479_+SINEAluAluSc
CAediting_895966chr12_56090523_+SINEAluAluSc
CAediting_895967chr12_56090529_+SINEAluAluSc
CAediting_895968chr12_56090533_+SINEAluAluSc
CAediting_895969chr12_56090537_+SINEAluAluSc
CAediting_895970chr12_56090550_+SINEAluAluSc
CAediting_895971chr12_56090558_+SINEAluAluSc
CAediting_895972chr12_56090564_+SINEAluAluSc
CAediting_895973chr12_56090565_+SINEAluAluSc
CAediting_895974chr12_56090576_+SINEAluAluSc
CAediting_895975chr12_56090594_+SINEAluAluSc
CAediting_895976chr12_56090614_+SINEAluAluSc
CAediting_895977chr12_56091126_+SINEAluAluSz6
CAediting_895978chr12_56091138_+SINEAluAluSz6
CAediting_895979chr12_56091153_+SINEAluAluSz6
CAediting_895980chr12_56091155_+SINEAluAluSz6
CAediting_895981chr12_56091171_+SINEAluAluSz6
CAediting_895982chr12_56091176_+SINEAluAluSz6
CAediting_895983chr12_56091181_+SINEAluAluSz6
CAediting_895984chr12_56091182_+SINEAluAluSz6
CAediting_895985chr12_56091214_+SINEAluAluSz6
CAediting_895986chr12_56091226_+SINEAluAluSz6
CAediting_895987chr12_56091236_+SINEAluAluSz6
CAediting_895988chr12_56091238_+SINEAluAluSz6
CAediting_895989chr12_56091984_+SINEAluFRAM
CAediting_895990chr12_56092013_+SINEAluFRAM
CAediting_895991chr12_56092019_+SINEAluFRAM
CAediting_895992chr12_56092023_+SINEAluFRAM
CAediting_895993chr12_56092134_+SINEAluAluSx3
CAediting_895994chr12_56092186_+SINEAluAluSx3
CAediting_895995chr12_56092232_+SINEAluAluSx3
CAediting_895996chr12_56092242_+SINEAluAluSx3
CAediting_895997chr12_56092268_+SINEAluAluSx3
CAediting_895998chr12_56092282_+SINEAluAluSx3
CAediting_895999chr12_56092286_+SINEAluAluSx3
CAediting_896000chr12_56092291_+SINEAluAluSx3
CAediting_896001chr12_56092304_+SINEAluAluSx3
CAediting_896002chr12_56092309_+SINEAluAluSx3
CAediting_896003chr12_56092310_+SINEAluAluSx3
CAediting_896004chr12_56092314_+SINEAluAluSx3
CAediting_896005chr12_56092330_+SINEAluAluSx3
CAediting_896006chr12_56092334_+SINEAluAluSx3
CAediting_896007chr12_56092339_+SINEAluAluSx3
CAediting_896008chr12_56092372_+SINEAluAluSx3
CAediting_896009chr12_56094719_+SINEAluAluSp
CAediting_896010chr12_56098337_+SINEAluAluY
CAediting_896011chr12_56099128_+SINEAluAluSq2
CAediting_896012chr12_56099230_+SINEAluAluSq2
CAediting_896013chr12_56099378_+SINEAluAluSx
CAediting_896014chr12_56099420_+SINEAluAluSx
CAediting_896015chr12_56099479_+SINEAluAluSx
CAediting_896016chr12_56099508_+SINEAluAluSx
CAediting_896017chr12_56099542_+SINEAluAluSx
CAediting_896018chr12_56099561_+SINEAluAluSx
CAediting_896019chr12_56100587_+SINEAluAluSx
CAediting_896020chr12_56100599_+SINEAluAluSx
CAediting_896021chr12_56100762_+SINEAluAluSq4
CAediting_896022chr12_56100852_+SINEAluAluSq4
CAediting_896023chr12_56100889_+SINEAluAluSq4
CAediting_896024chr12_56102770_+SINEAluAluJr
CAediting_896025chr12_56102787_+SINEAluAluJr
CAediting_896026chr12_56102793_+SINEAluAluJr

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RNA A-to-I editing events in the alternative splicing sites for ERBB3

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000065361.13.ERBB3.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000065361.13.ERBB3.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ERBB3

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
STAD.CAediting_895920.ENSG00000065361.ERBB3.png
Soverview

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Protein coding region RNA A-to-I editings for ERBB3

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ERBB3

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_895882chr12_56085489_+ENSG00000065361.13ENST00000411731hsa-miR-513a-5p56085483560854897mer-m85608547056085490143.00-17.78
CAediting_895882chr12_56085489_+ENSG00000065361.13ENST00000411731hsa-miR-513a-5p56085483560854897mer-m85608547056085490143.00-17.78
CAediting_895882chr12_56085489_+ENSG00000065361.13ENST00000411731hsa-miR-63856085488560854947mer-1a5608547056085494147.00-27.54
CAediting_895890chr12_56085569_+ENSG00000065361.13ENST00000411731hsa-miR-3158-3p56085566560855727mer-m85608555356085573150.00-19.46
CAediting_895890chr12_56085569_+ENSG00000065361.13ENST00000411731hsa-miR-3158-3p56085566560855727mer-m85608555356085573150.00-19.46
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000267101hsa-miR-317656102767561027737mer-m85610275656102774156.00-22.92
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000267101hsa-miR-3922-3p56102767561027737mer-m85610274956102774158.00-21.07
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000267101hsa-miR-6878-3p56102766561027727mer-m85610275156102773150.00-25.27
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000551242hsa-miR-317656102767561027737mer-m85610275656102774156.00-22.92
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000551242hsa-miR-3922-3p56102767561027737mer-m85610274956102774158.00-21.07
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000551242hsa-miR-6878-3p56102766561027727mer-m85610275156102773150.00-25.27
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000550070hsa-miR-317656102767561027737mer-m85610275656102774156.00-22.92
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000550070hsa-miR-3922-3p56102767561027737mer-m85610274956102774158.00-21.07
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000550070hsa-miR-6878-3p56102766561027727mer-m85610275156102773150.00-25.27
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000553131hsa-miR-317656102767561027737mer-m85610275656102774156.00-22.92
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000553131hsa-miR-3922-3p56102767561027737mer-m85610274956102774158.00-21.07
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000553131hsa-miR-6878-3p56102766561027727mer-m85610275156102773150.00-25.27
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000549832hsa-miR-317656102767561027737mer-m85610275656102774156.00-22.92
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000549832hsa-miR-3922-3p56102767561027737mer-m85610274956102774158.00-21.07
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000549832hsa-miR-6878-3p56102766561027727mer-m85610275156102773150.00-25.27
CAediting_896025chr12_56102787_+ENSG00000065361.13ENST00000267101hsa-miR-4716-5p56102781561027877mer-m85610276756102788144.00-10.91
CAediting_896025chr12_56102787_+ENSG00000065361.13ENST00000551242hsa-miR-4716-5p56102781561027877mer-m85610276756102788144.00-10.91
CAediting_896025chr12_56102787_+ENSG00000065361.13ENST00000550070hsa-miR-4716-5p56102781561027877mer-m85610276756102788144.00-10.91
CAediting_896025chr12_56102787_+ENSG00000065361.13ENST00000553131hsa-miR-4716-5p56102781561027877mer-m85610276756102788144.00-10.91
CAediting_896025chr12_56102787_+ENSG00000065361.13ENST00000549832hsa-miR-4716-5p56102781561027877mer-m85610276756102788144.00-10.91
CAediting_895883chr12_56085490_+ENSG00000065361.13ENST00000411731hsa-miR-319956085488560854947mer-1a5608547556085494141.00-18.98
CAediting_895883chr12_56085490_+ENSG00000065361.13ENST00000411731hsa-miR-319956085488560854947mer-1a5608547556085494141.00-18.98
CAediting_895889chr12_56085546_+ENSG00000065361.13ENST00000411731hsa-miR-317656085543560855497mer-m85608553256085550156.00-23.27
CAediting_895889chr12_56085546_+ENSG00000065361.13ENST00000411731hsa-miR-3922-3p56085543560855497mer-m85608552556085550157.00-21.45
CAediting_895889chr12_56085546_+ENSG00000065361.13ENST00000411731hsa-miR-6878-3p56085542560855487mer-m85608552956085549148.00-24.79

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_895882chr12_56085489_+ENSG00000065361.13ENST00000411731hsa-miR-10399-5p56085484560854907mer-m85608546756085491147-14.47
CAediting_895883chr12_56085490_+ENSG00000065361.13ENST00000411731hsa-miR-10399-5p56085484560854907mer-m85608546756085491147-14.47
CAediting_895886chr12_56085520_+ENSG00000065361.13ENST00000411731hsa-miR-18a-3p56085514560855218mer-1a5608550056085521151-23.58
CAediting_895889chr12_56085546_+ENSG00000065361.13ENST00000411731hsa-miR-3663-5p56085543560855497mer-m85608553156085550144-20.26
CAediting_895881chr12_56085483_+ENSG00000065361.13ENST00000411731hsa-miR-3934-5p56085480560854867mer-m85608546656085487152-22.21
CAediting_895885chr12_56085515_+ENSG00000065361.13ENST00000411731hsa-miR-4667-3p56085511560855177mer-m85608549856085518155-24.86
CAediting_895887chr12_56085532_+ENSG00000065361.13ENST00000411731hsa-miR-4695-3p56085527560855348mer-1a5608550956085534153-27.15
CAediting_895883chr12_56085490_+ENSG00000065361.13ENST00000411731hsa-miR-5089-5p56085488560854947mer-m85608547456085495148-13.62
CAediting_895887chr12_56085532_+ENSG00000065361.13ENST00000411731hsa-miR-513c-5p56085525560855317mer-m85608551056085532155-18.54
CAediting_895887chr12_56085532_+ENSG00000065361.13ENST00000411731hsa-miR-514b-5p56085525560855317mer-m85608551156085532148-17.65
CAediting_895881chr12_56085483_+ENSG00000065361.13ENST00000411731hsa-miR-552-3p56085481560854888mer-1a5608546656085488146-16.65
CAediting_895889chr12_56085546_+ENSG00000065361.13ENST00000411731hsa-miR-613156085544560855507mer-m85608553356085551140-16.72
CAediting_895882chr12_56085489_+ENSG00000065361.13ENST00000411731hsa-miR-6504-3p56085484560854907mer-m85608547056085491149-14.65
CAediting_895883chr12_56085490_+ENSG00000065361.13ENST00000411731hsa-miR-6504-3p56085484560854907mer-m85608547056085491149-14.65
CAediting_895890chr12_56085569_+ENSG00000065361.13ENST00000411731hsa-miR-6823-5p56085567560855737mer-m85608555456085574143-17.8
CAediting_895889chr12_56085546_+ENSG00000065361.13ENST00000411731hsa-miR-6848-3p56085542560855487mer-m85608553256085549142-15.32
CAediting_895884chr12_56085511_+ENSG00000065361.13ENST00000411731hsa-miR-6878-3p56085504560855118mer-1a5608549156085511142-14.14
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000267101hsa-miR-193a-5p56102789561027957mer-m85610277056102796142-19.06
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000267101hsa-miR-200c-5p56102787561027937mer-m85610277356102794140-12.23
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000267101hsa-miR-3663-5p56102767561027737mer-m85610275556102774144-20.26
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000267101hsa-miR-550a-3p56102787561027937mer-m85610277356102794145-13.6
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000267101hsa-miR-550a-3p56102787561027937mer-m85610277356102794145-13.6
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000267101hsa-miR-550a-3p56102787561027937mer-m85610277356102794145-13.6
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000267101hsa-miR-613156102768561027747mer-m85610275756102775140-13.79
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000267101hsa-miR-6848-3p56102766561027727mer-m85610275656102773142-15.32
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000551242hsa-miR-193a-5p56102789561027957mer-m85610277056102796142-19.06
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000551242hsa-miR-200c-5p56102787561027937mer-m85610277356102794140-12.23
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000551242hsa-miR-3663-5p56102767561027737mer-m85610275556102774144-20.26
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000551242hsa-miR-550a-3p56102787561027937mer-m85610277356102794145-13.6
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000551242hsa-miR-550a-3p56102787561027937mer-m85610277356102794145-13.6
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000551242hsa-miR-550a-3p56102787561027937mer-m85610277356102794145-13.6
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000551242hsa-miR-613156102768561027747mer-m85610275756102775140-13.79
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000551242hsa-miR-6848-3p56102766561027727mer-m85610275656102773142-15.32
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000550070hsa-miR-193a-5p56102789561027957mer-m85610277056102796142-19.06
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000550070hsa-miR-200c-5p56102787561027937mer-m85610277356102794140-12.23
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000550070hsa-miR-3663-5p56102767561027737mer-m85610275556102774144-20.26
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000550070hsa-miR-550a-3p56102787561027937mer-m85610277356102794145-13.6
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000550070hsa-miR-550a-3p56102787561027937mer-m85610277356102794145-13.6
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000550070hsa-miR-550a-3p56102787561027937mer-m85610277356102794145-13.6
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000550070hsa-miR-613156102768561027747mer-m85610275756102775140-13.79
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000550070hsa-miR-6848-3p56102766561027727mer-m85610275656102773142-15.32
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000553131hsa-miR-193a-5p56102789561027957mer-m85610277056102796142-19.06
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000553131hsa-miR-200c-5p56102787561027937mer-m85610277356102794140-12.23
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000553131hsa-miR-3663-5p56102767561027737mer-m85610275556102774144-20.26
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000553131hsa-miR-550a-3p56102787561027937mer-m85610277356102794145-13.6
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000553131hsa-miR-550a-3p56102787561027937mer-m85610277356102794145-13.6
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000553131hsa-miR-550a-3p56102787561027937mer-m85610277356102794145-13.6
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000553131hsa-miR-613156102768561027747mer-m85610275756102775140-13.79
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000553131hsa-miR-6848-3p56102766561027727mer-m85610275656102773142-15.32
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000549832hsa-miR-193a-5p56102789561027957mer-m85610277056102796142-19.06
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000549832hsa-miR-200c-5p56102787561027937mer-m85610277356102794140-12.23
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000549832hsa-miR-3663-5p56102767561027737mer-m85610275556102774144-20.26
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000549832hsa-miR-550a-3p56102787561027937mer-m85610277356102794145-13.6
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000549832hsa-miR-550a-3p56102787561027937mer-m85610277356102794145-13.6
CAediting_896026chr12_56102793_+ENSG00000065361.13ENST00000549832hsa-miR-550a-3p56102787561027937mer-m85610277356102794145-13.6
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000549832hsa-miR-613156102768561027747mer-m85610275756102775140-13.79
CAediting_896024chr12_56102770_+ENSG00000065361.13ENST00000549832hsa-miR-6848-3p56102766561027727mer-m85610275656102773142-15.32

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_980496chr14_31014685_-ENSG00000065361.13ENST00000411731hsa-miR-624-3p56085568560855747mer-m85608555556085575156-16.49
CAediting_980496chr14_31014685_-ENSG00000065361.13ENST00000411731hsa-miR-624-3p56085384560853907mer-m85608537156085391140-18.73
CAediting_393chr1_1167164_+ENSG00000065361.13ENST00000411731hsa-miR-200b-3p56085493560854997mer-m85608547956085500140-10.3
CAediting_980496chr14_31014685_-ENSG00000065361.13ENST00000551085hsa-miR-624-3p56101756561017638mer-1a5610174156101763144-14.83
CAediting_980496chr14_31014685_-ENSG00000065361.13ENST00000551242hsa-miR-624-3p56101756561017638mer-1a5610174156101763144-14.83
CAediting_1229415chr17_67471547_+ENSG00000065361.13ENST00000550869hsa-miR-548aa56095681560956877mer-m85609566456095688146-7.9
CAediting_1054808chr15_66496985_-ENSG00000065361.13ENST00000551085hsa-miR-451256101927561019337mer-m85610191456101934150-23.01
CAediting_228905chr2_188297554_+ENSG00000065361.13ENST00000551085hsa-miR-561-3p56101957561019648mer-1a5610194356101964140-6.45
CAediting_1054808chr15_66496985_-ENSG00000065361.13ENST00000551242hsa-miR-451256101927561019337mer-m85610191456101934150-23.01
CAediting_228905chr2_188297554_+ENSG00000065361.13ENST00000551242hsa-miR-561-3p56101957561019648mer-1a5610194356101964140-6.45

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_580943chr7_100356700_+ENSG00000065361.13ENST00000551085hsa-miR-6840-3p56101838561018447mer-m85610182456101845149-21.63
CAediting_580943chr7_100356700_+ENSG00000065361.13ENST00000551085hsa-miR-6840-3p56101579561015857mer-m85610156556101586145-22.47
CAediting_580943chr7_100356700_+ENSG00000065361.13ENST00000551242hsa-miR-6840-3p56101838561018447mer-m85610182456101845149-21.63
CAediting_580943chr7_100356700_+ENSG00000065361.13ENST00000551242hsa-miR-6840-3p56101579561015857mer-m85610156556101586145-22.47

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ERBB3

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ERBB3

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for ERBB3

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for ERBB3

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for ERBB3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
ERBB3P21860DB11652TucatinibReceptor tyrosine-protein kinase erbB-3 SmallMoleculeDrugapproved|investigational

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RelatedDiseases for ERBB3

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
ERBB3C0036341Schizophrenia3PSYGENET
ERBB3C1843478Lethal Congenital Contracture Syndrome 23CTD_human;GENOMICS_ENGLAND;ORPHANET
ERBB3C0006142Malignant neoplasm of breast2CTD_human
ERBB3C0678222Breast Carcinoma2CTD_human
ERBB3C1257931Mammary Neoplasms, Human2CTD_human
ERBB3C1458155Mammary Neoplasms2CTD_human
ERBB3C4704874Mammary Carcinoma, Human2CTD_human
ERBB3C0005586Bipolar Disorder1PSYGENET
ERBB3C0011570Mental Depression1PSYGENET
ERBB3C0016978gallbladder neoplasm1CTD_human
ERBB3C0024121Lung Neoplasms1CTD_human
ERBB3C0027627Neoplasm Metastasis1CTD_human
ERBB3C0033578Prostatic Neoplasms1CTD_human
ERBB3C0041696Unipolar Depression1PSYGENET
ERBB3C0153452Malignant neoplasm of gallbladder1CTD_human
ERBB3C0235874Disease Exacerbation1CTD_human
ERBB3C0242379Malignant neoplasm of lung1CTD_human
ERBB3C0376358Malignant neoplasm of prostate1CTD_human
ERBB3C1269683Major Depressive Disorder1PSYGENET
ERBB3C2931822Nasopharyngeal carcinoma1CTD_human
ERBB3C4746575ERYTHROLEUKEMIA, FAMILIAL, SUSCEPTIBILITY TO1UNIPROT