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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: EPHB2 (CAeditome ID:2048)

Gene summary for EPHB2

check button Gene summary
Gene informationGene symbol

EPHB2

Gene ID

2048

Gene nameEPH receptor B2
SynonymsBDPLT22|CAPB|DRT|EK5|EPHT3|ERK|Hek5|PCBC|Tyro5
Cytomap

1p36.12

Type of geneprotein-coding
Descriptionephrin type-B receptor 2EPH-like kinase 5developmentally-regulated Eph-related tyrosine kinaseelk-related tyrosine kinaseeph tyrosine kinase 3protein-tyrosine kinase HEK5renal carcinoma antigen NY-REN-47tyrosine-protein kinase TYRO5tyrosine-protei
Modification date20210518
UniProtAcc

P29323

Context- 33903122(EPHB2 activates beta-catenin to enhance cancer stem cell properties and drive sorafenib resistance in hepatocellular carcinoma)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
EPHB2

GO:0005654

Ephrin type-B receptor 2

0000052

EPHB2

GO:0005886

Ephrin type-B receptor 2

0000052


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RNA A-to-I events for EPHB2

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000133216.15

check button RNA A-to-I editing events in Cancer.
CAediting_24980(22731689, +), CAediting_24981(22734631, +), CAediting_24982(22735394, +), CAediting_24983(22735421, +), CAediting_24984(22742607, +), CAediting_24985(22742611, +), CAediting_24986(22742619, +), CAediting_24987(22742624, +), CAediting_24988(22742636, +), CAediting_24989(22742646, +), CAediting_24990(22742647, +), CAediting_24991(22742648, +), CAediting_24992(22743004, +), CAediting_24993(22743031, +), CAediting_24994(22743490, +), CAediting_24995(22743551, +), CAediting_24996(22743571, +), CAediting_24997(22743597, +), CAediting_24998(22743601, +), CAediting_24999(22744559, +), CAediting_25000(22744565, +), CAediting_25001(22744568, +), CAediting_25002(22744573, +), CAediting_25003(22744575, +), CAediting_25004(22744581, +), CAediting_25005(22744585, +), CAediting_25006(22744594, +), CAediting_25007(22744599, +), CAediting_25008(22744600, +), CAediting_25009(22744604, +), CAediting_25010(22744607, +), CAediting_25011(22744654, +), CAediting_25012(22744660, +), CAediting_25013(22744735, +), CAediting_25014(22744741, +), CAediting_25015(22744752, +), CAediting_25016(22744756, +), CAediting_25017(22744762, +), CAediting_25018(22752242, +), CAediting_25019(22752243, +), CAediting_25020(22752270, +), CAediting_25021(22752382, +), CAediting_25022(22752394, +), CAediting_25023(22753057, +), CAediting_25024(22768467, +), CAediting_25025(22768505, +), CAediting_25026(22781205, +), CAediting_25027(22782187, +), CAediting_25028(22787517, +), CAediting_25029(22787555, +), CAediting_25030(22791505, +), CAediting_25031(22791508, +), CAediting_25032(22791513, +), CAediting_25033(22791525, +), CAediting_25034(22791550, +), CAediting_25035(22791551, +), CAediting_25036(22791552, +), CAediting_25037(22791555, +), CAediting_25038(22791563, +), CAediting_25039(22791568, +), CAediting_25040(22791596, +), CAediting_25041(22796125, +), CAediting_25042(22796133, +), CAediting_25043(22796171, +), CAediting_25044(22796173, +), CAediting_25045(22796177, +), CAediting_25046(22796202, +), CAediting_25047(22796208, +), CAediting_25048(22796211, +), CAediting_25049(22796216, +), CAediting_25050(22798022, +), CAediting_25051(22798025, +), CAediting_25052(22798065, +), CAediting_25053(22798100, +), CAediting_25054(22798121, +), CAediting_25055(22798151, +), CAediting_25056(22798153, +), CAediting_25057(22808023, +), CAediting_25058(22822221, +), CAediting_25059(22830823, +), CAediting_25060(22834741, +), CAediting_25061(22834806, +), CAediting_25062(22834814, +), CAediting_25063(22834840, +), CAediting_25064(22835117, +), CAediting_25065(22835224, +), CAediting_25066(22835249, +), CAediting_25067(22835259, +), CAediting_25068(22835282, +), CAediting_25069(22835319, +), CAediting_25070(22843610, +), CAediting_25071(22884523, +), CAediting_25072(22897622, +), CAediting_25073(22897666, +), CAediting_25074(22897886, +), CAediting_25075(22897893, +), CAediting_25076(22897919, +), CAediting_25077(22897982, +), CAediting_25078(22898017, +), CAediting_25079(22898022, +), CAediting_25080(22898023, +), CAediting_25081(22898028, +), CAediting_25082(22898106, +), CAediting_25083(22899012, +), CAediting_25084(22899072, +), CAediting_25085(22899316, +), CAediting_25086(22899337, +), CAediting_25087(22899346, +), CAediting_25088(22899380, +), CAediting_25089(22899381, +), CAediting_25090(22899422, +), CAediting_25091(22899806, +), CAediting_25092(22899807, +), CAediting_25093(22899811, +), CAediting_25094(22899815, +), CAediting_25095(22899833, +), CAediting_25096(22899872, +), CAediting_25097(22899887, +), CAediting_25098(22900052, +), CAediting_25099(22901858, +), CAediting_25100(22901890, +), CAediting_25101(22901905, +), CAediting_25102(22901912, +), CAediting_25103(22901925, +), CAediting_25104(22901929, +), CAediting_25105(22901951, +), CAediting_25106(22901955, +), CAediting_25107(22901965, +), CAediting_25108(22901967, +), CAediting_25109(22901968, +), CAediting_25110(22902031, +), CAediting_25111(22902060, +), CAediting_25112(22902065, +), CAediting_25113(22902078, +), CAediting_25114(22904172, +), CAediting_25115(22904173, +), CAediting_25116(22904208, +),

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RNA editing positional annotations for EPHB2 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_24980chr1_22731689_+intronic
CAediting_24981chr1_22734631_+intronic
CAediting_24982chr1_22735394_+intronic
CAediting_24983chr1_22735421_+intronic
CAediting_24984chr1_22742607_+intronic
CAediting_24985chr1_22742611_+intronic
CAediting_24986chr1_22742619_+intronic
CAediting_24987chr1_22742624_+intronic
CAediting_24988chr1_22742636_+intronic
CAediting_24989chr1_22742646_+intronic
CAediting_24990chr1_22742647_+intronic
CAediting_24991chr1_22742648_+intronic
CAediting_24992chr1_22743004_+intronic
CAediting_24993chr1_22743031_+intronic
CAediting_24994chr1_22743490_+intronic
CAediting_24995chr1_22743551_+intronic
CAediting_24996chr1_22743571_+intronic
CAediting_24997chr1_22743597_+intronic
CAediting_24998chr1_22743601_+intronic
CAediting_24999chr1_22744559_+intronic
CAediting_25000chr1_22744565_+intronic
CAediting_25001chr1_22744568_+intronic
CAediting_25002chr1_22744573_+intronic
CAediting_25003chr1_22744575_+intronic
CAediting_25004chr1_22744581_+intronic
CAediting_25005chr1_22744585_+intronic
CAediting_25006chr1_22744594_+intronic
CAediting_25007chr1_22744599_+intronic
CAediting_25008chr1_22744600_+intronic
CAediting_25009chr1_22744604_+intronic
CAediting_25010chr1_22744607_+intronic
CAediting_25011chr1_22744654_+intronic
CAediting_25012chr1_22744660_+intronic
CAediting_25013chr1_22744735_+intronic
CAediting_25014chr1_22744741_+intronic
CAediting_25015chr1_22744752_+intronic
CAediting_25016chr1_22744756_+intronic
CAediting_25017chr1_22744762_+intronic
CAediting_25018chr1_22752242_+intronic
CAediting_25019chr1_22752243_+intronic
CAediting_25020chr1_22752270_+intronic
CAediting_25021chr1_22752382_+intronic
CAediting_25022chr1_22752394_+intronic
CAediting_25023chr1_22753057_+intronic
CAediting_25024chr1_22768467_+intronic
CAediting_25025chr1_22768505_+intronic
CAediting_25026chr1_22781205_+intronic
CAediting_25027chr1_22782187_+intronic
CAediting_25028chr1_22787517_+intronic
CAediting_25029chr1_22787555_+intronic
CAediting_25030chr1_22791505_+intronic
CAediting_25031chr1_22791508_+intronic
CAediting_25032chr1_22791513_+intronic
CAediting_25033chr1_22791525_+intronic
CAediting_25034chr1_22791550_+intronic
CAediting_25035chr1_22791551_+intronic
CAediting_25036chr1_22791552_+intronic
CAediting_25037chr1_22791555_+intronic
CAediting_25038chr1_22791563_+intronic
CAediting_25039chr1_22791568_+intronic
CAediting_25040chr1_22791596_+intronic
CAediting_25041chr1_22796125_+intronic
CAediting_25042chr1_22796133_+intronic
CAediting_25043chr1_22796171_+intronic
CAediting_25044chr1_22796173_+intronic
CAediting_25045chr1_22796177_+intronic
CAediting_25046chr1_22796202_+intronic
CAediting_25047chr1_22796208_+intronic
CAediting_25048chr1_22796211_+intronic
CAediting_25049chr1_22796216_+intronic
CAediting_25050chr1_22798022_+intronic
CAediting_25051chr1_22798025_+intronic
CAediting_25052chr1_22798065_+intronic
CAediting_25053chr1_22798100_+intronic
CAediting_25054chr1_22798121_+intronic
CAediting_25055chr1_22798151_+intronic
CAediting_25056chr1_22798153_+intronic
CAediting_25057chr1_22808023_+ncRNA_intronic
CAediting_25058chr1_22822221_+ncRNA_intronic
CAediting_25059chr1_22830823_+ncRNA_intronic
CAediting_25060chr1_22834741_+ncRNA_intronic
CAediting_25061chr1_22834806_+ncRNA_intronic
CAediting_25062chr1_22834814_+ncRNA_intronic
CAediting_25063chr1_22834840_+ncRNA_intronic
CAediting_25064chr1_22835117_+ncRNA_intronic
CAediting_25065chr1_22835224_+ncRNA_intronic
CAediting_25066chr1_22835249_+ncRNA_intronic
CAediting_25067chr1_22835259_+ncRNA_intronic
CAediting_25068chr1_22835282_+ncRNA_intronic
CAediting_25069chr1_22835319_+ncRNA_intronic
CAediting_25070chr1_22843610_+ncRNA_intronic
CAediting_25071chr1_22884523_+ncRNA_intronic
CAediting_25072chr1_22897622_+intronic
CAediting_25073chr1_22897666_+intronic
CAediting_25074chr1_22897886_+intronic
CAediting_25075chr1_22897893_+intronic
CAediting_25076chr1_22897919_+intronic
CAediting_25077chr1_22897982_+intronic
CAediting_25078chr1_22898017_+intronic
CAediting_25079chr1_22898022_+intronic
CAediting_25080chr1_22898023_+intronic
CAediting_25081chr1_22898028_+intronic
CAediting_25082chr1_22898106_+intronic
CAediting_25083chr1_22899012_+intronic
CAediting_25084chr1_22899072_+intronic
CAediting_25085chr1_22899316_+intronic
CAediting_25086chr1_22899337_+intronic
CAediting_25087chr1_22899346_+intronic
CAediting_25088chr1_22899380_+intronic
CAediting_25089chr1_22899381_+intronic
CAediting_25090chr1_22899422_+intronic
CAediting_25091chr1_22899806_+intronic
CAediting_25092chr1_22899807_+intronic
CAediting_25093chr1_22899811_+intronic
CAediting_25094chr1_22899815_+intronic
CAediting_25095chr1_22899833_+intronic
CAediting_25096chr1_22899872_+intronic
CAediting_25097chr1_22899887_+intronic
CAediting_25098chr1_22900052_+intronic
CAediting_25099chr1_22901858_+intronic
CAediting_25100chr1_22901890_+intronic
CAediting_25101chr1_22901905_+intronic
CAediting_25102chr1_22901912_+intronic
CAediting_25103chr1_22901925_+intronic
CAediting_25104chr1_22901929_+intronic
CAediting_25105chr1_22901951_+intronic
CAediting_25106chr1_22901955_+intronic
CAediting_25107chr1_22901965_+intronic
CAediting_25108chr1_22901967_+intronic
CAediting_25109chr1_22901968_+intronic
CAediting_25110chr1_22902031_+intronic
CAediting_25111chr1_22902060_+intronic
CAediting_25112chr1_22902065_+intronic
CAediting_25113chr1_22902078_+intronic
CAediting_25114chr1_22904172_+intronic
CAediting_25115chr1_22904173_+intronic
CAediting_25116chr1_22904208_+intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_24980chr1_22731689_+SINEAluAluSg
CAediting_24981chr1_22734631_+SINEAluAluSx
CAediting_24982chr1_22735394_+SINEAluAluJr
CAediting_24983chr1_22735421_+SINEAluAluJr
CAediting_24984chr1_22742607_+SINEAluAluJr
CAediting_24985chr1_22742611_+SINEAluAluJr
CAediting_24986chr1_22742619_+SINEAluAluJr
CAediting_24987chr1_22742624_+SINEAluAluJr
CAediting_24988chr1_22742636_+SINEAluAluJr
CAediting_24989chr1_22742646_+SINEAluAluJr
CAediting_24990chr1_22742647_+SINEAluAluJr
CAediting_24991chr1_22742648_+SINEAluAluJr
CAediting_24992chr1_22743004_+SINEAluAluJr
CAediting_24993chr1_22743031_+SINEAluAluJr
CAediting_24994chr1_22743490_+SINEAluAluSz6
CAediting_24995chr1_22743551_+SINEAluAluSz6
CAediting_24996chr1_22743571_+SINEAluAluSz6
CAediting_24997chr1_22743597_+SINEAluAluSz6
CAediting_24998chr1_22743601_+SINEAluAluSz6
CAediting_24999chr1_22744559_+SINEAluAluJo
CAediting_25000chr1_22744565_+SINEAluAluJo
CAediting_25001chr1_22744568_+SINEAluAluJo
CAediting_25002chr1_22744573_+SINEAluAluJo
CAediting_25003chr1_22744575_+SINEAluAluJo
CAediting_25004chr1_22744581_+SINEAluAluJo
CAediting_25005chr1_22744585_+SINEAluAluJo
CAediting_25006chr1_22744594_+SINEAluAluJo
CAediting_25007chr1_22744599_+SINEAluAluJo
CAediting_25008chr1_22744600_+SINEAluAluJo
CAediting_25009chr1_22744604_+SINEAluAluJo
CAediting_25010chr1_22744607_+SINEAluAluJo
CAediting_25011chr1_22744654_+SINEAluAluJo
CAediting_25012chr1_22744660_+SINEAluAluJo
CAediting_25013chr1_22744735_+SINEAluAluJo
CAediting_25014chr1_22744741_+SINEAluAluJo
CAediting_25015chr1_22744752_+SINEAluAluJo
CAediting_25016chr1_22744756_+SINEAluAluJo
CAediting_25017chr1_22744762_+SINEAluAluJo
CAediting_25018chr1_22752242_+SINEAluAluJb
CAediting_25019chr1_22752243_+SINEAluAluJb
CAediting_25020chr1_22752270_+SINEAluAluJb
CAediting_25021chr1_22752382_+SINEAluAluJb
CAediting_25022chr1_22752394_+SINEAluAluJb
CAediting_25023chr1_22753057_+SINEAluAluJo
CAediting_25024chr1_22768467_+SINEAluAluJr
CAediting_25025chr1_22768505_+SINEAluAluJr
CAediting_25026chr1_22781205_+SINEAluAluY
CAediting_25027chr1_22782187_+SINEMIRMIRb
CAediting_25028chr1_22787517_+SINEAluAluJo
CAediting_25029chr1_22787555_+SINEAluAluJo
CAediting_25030chr1_22791505_+SINEAluFLAM_C
CAediting_25031chr1_22791508_+SINEAluFLAM_C
CAediting_25032chr1_22791513_+SINEAluFLAM_C
CAediting_25033chr1_22791525_+SINEAluFLAM_C
CAediting_25034chr1_22791550_+SINEAluFLAM_C
CAediting_25035chr1_22791551_+SINEAluFLAM_C
CAediting_25036chr1_22791552_+SINEAluFLAM_C
CAediting_25037chr1_22791555_+SINEAluFLAM_C
CAediting_25038chr1_22791563_+SINEAluFLAM_C
CAediting_25039chr1_22791568_+SINEAluFLAM_C
CAediting_25040chr1_22791596_+SINEAluFLAM_C
CAediting_25041chr1_22796125_+LINEL2L2a
CAediting_25042chr1_22796133_+LINEL2L2a
CAediting_25043chr1_22796171_+LINEL2L2a
CAediting_25044chr1_22796173_+LINEL2L2a
CAediting_25045chr1_22796177_+LINEL2L2a
CAediting_25046chr1_22796202_+LINEL2L2a
CAediting_25047chr1_22796208_+LINEL2L2a
CAediting_25048chr1_22796211_+LINEL2L2a
CAediting_25049chr1_22796216_+LINEL2L2a
CAediting_25050chr1_22798022_+LINEL2L2a
CAediting_25051chr1_22798025_+LINEL2L2a
CAediting_25052chr1_22798065_+LINEL2L2a
CAediting_25053chr1_22798100_+LINEL2L2a
CAediting_25054chr1_22798121_+LINEL2L2a
CAediting_25055chr1_22798151_+LINEL2L2a
CAediting_25056chr1_22798153_+LINEL2L2a
CAediting_25057chr1_22808023_+SINEAluAluSx
CAediting_25058chr1_22822221_+SINEAluAluJb
CAediting_25059chr1_22830823_+SINEAluAluSg4
CAediting_25060chr1_22834741_+SINEAluAluSz
CAediting_25061chr1_22834806_+SINEAluAluSz
CAediting_25062chr1_22834814_+SINEAluAluSz
CAediting_25063chr1_22834840_+SINEAluAluSz
CAediting_25064chr1_22835117_+SINEAluAluJb
CAediting_25065chr1_22835224_+SINEAluAluJb
CAediting_25066chr1_22835249_+SINEAluAluJb
CAediting_25067chr1_22835259_+SINEAluAluJb
CAediting_25068chr1_22835282_+SINEAluAluJb
CAediting_25069chr1_22835319_+SINEAluAluJb
CAediting_25070chr1_22843610_+SINEAluAluSx1
CAediting_25071chr1_22884523_+SINEAluAluSg
CAediting_25072chr1_22897622_+SINEAluAluSz
CAediting_25073chr1_22897666_+SINEAluAluSz
CAediting_25074chr1_22897886_+SINEAluAluJb
CAediting_25075chr1_22897893_+SINEAluAluJb
CAediting_25076chr1_22897919_+SINEAluAluJb
CAediting_25077chr1_22897982_+SINEAluAluJb
CAediting_25078chr1_22898017_+SINEAluAluJb
CAediting_25079chr1_22898022_+SINEAluAluJb
CAediting_25080chr1_22898023_+SINEAluAluJb
CAediting_25081chr1_22898028_+SINEAluAluJb
CAediting_25082chr1_22898106_+SINEAluAluJb
CAediting_25083chr1_22899012_+SINEAluAluSp
CAediting_25084chr1_22899072_+SINEAluAluSp
CAediting_25085chr1_22899316_+SINEAluAluSp
CAediting_25086chr1_22899337_+SINEAluAluSp
CAediting_25087chr1_22899346_+SINEAluAluSp
CAediting_25088chr1_22899380_+SINEAluAluSp
CAediting_25089chr1_22899381_+SINEAluAluSp
CAediting_25090chr1_22899422_+SINEAluAluSp
CAediting_25091chr1_22899806_+SINEAluAluJr
CAediting_25092chr1_22899807_+SINEAluAluJr
CAediting_25093chr1_22899811_+SINEAluAluJr
CAediting_25094chr1_22899815_+SINEAluAluJr
CAediting_25095chr1_22899833_+SINEAluAluJr
CAediting_25096chr1_22899872_+SINEAluAluJr
CAediting_25097chr1_22899887_+SINEAluAluJr
CAediting_25098chr1_22900052_+SINEAluAluSx
CAediting_25099chr1_22901858_+SINEAluAluJb
CAediting_25100chr1_22901890_+SINEAluAluJb
CAediting_25101chr1_22901905_+SINEAluAluJb
CAediting_25102chr1_22901912_+SINEAluAluJb
CAediting_25103chr1_22901925_+SINEAluAluJb
CAediting_25104chr1_22901929_+SINEAluAluJb
CAediting_25105chr1_22901951_+SINEAluAluJb
CAediting_25106chr1_22901955_+SINEAluAluJb
CAediting_25107chr1_22901965_+SINEAluAluJb
CAediting_25108chr1_22901967_+SINEAluAluJb
CAediting_25109chr1_22901968_+SINEAluAluJb
CAediting_25110chr1_22902031_+SINEAluAluJb
CAediting_25111chr1_22902060_+SINEAluAluJb
CAediting_25112chr1_22902065_+SINEAluAluJb
CAediting_25113chr1_22902078_+SINEAluAluJb
CAediting_25114chr1_22904172_+SINEAluAluSz6
CAediting_25115chr1_22904173_+SINEAluAluSz6
CAediting_25116chr1_22904208_+SINEAluAluSz6

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RNA A-to-I editing events in the alternative splicing sites for EPHB2

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000133216.15.EPHB2.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000133216.15.EPHB2.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for EPHB2

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for EPHB2

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for EPHB2

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_748296chr10_51299626_+ENSG00000133216.15ENST00000400191hsa-miR-605-3p22914987229149948mer-1a2291497222914994167-24.39
CAediting_748296chr10_51299626_+ENSG00000133216.15ENST00000400191hsa-miR-605-3p22915079229150857mer-m82291506322915086147-14.11
CAediting_980496chr14_31014685_-ENSG00000133216.15ENST00000400191hsa-miR-624-3p22921256229212627mer-m82292124322921263155-21.85
CAediting_980496chr14_31014685_-ENSG00000133216.15ENST00000400191hsa-miR-624-3p22921418229214247mer-m82292140122921425147-15.72
CAediting_1306324chr19_13836464_-ENSG00000133216.15ENST00000400191hsa-miR-27a-3p22916967229169748mer-1a2291695422916974153-13.56
CAediting_688081chr9_63819627_+ENSG00000133216.15ENST00000374627hsa-miR-4477b22913432229134387mer-m82291341822913439164-16.1
CAediting_1160181chr17_7017644_-ENSG00000133216.15ENST00000544305hsa-miR-195-3p22891257228912637mer-m82289124222891264142-11.97
CAediting_1054808chr15_66496985_-ENSG00000133216.15ENST00000400191hsa-miR-451222914965229149717mer-m82291495122914972146-16.03
CAediting_1054808chr15_66496985_-ENSG00000133216.15ENST00000400191hsa-miR-451222916026229160316mer2291601122916032140-21.42
CAediting_1054808chr15_66496985_-ENSG00000133216.15ENST00000400191hsa-miR-451222917317229173248mer-1a2291730322917324141-17.58
CAediting_1229414chr17_67471546_+ENSG00000133216.15ENST00000400191hsa-miR-548aa22918675229186817mer-m82291865722918682149-17
CAediting_1351755chr19_40282625_-ENSG00000133216.15ENST00000400191hsa-miR-64122916420229164256mer2291640022916426140-22.55
CAediting_86358chr1_109598906_+ENSG00000133216.15ENST00000400191hsa-miR-197-5p22916492229164987mer-m82291647822916499162-26.97
CAediting_117844chr1_162342605_+ENSG00000133216.15ENST00000400191hsa-miR-556-3p22914647229146537mer-m82291463522914654150-9.98
CAediting_77128chr1_85133844_+ENSG00000133216.15ENST00000400191hsa-miR-4423-3p22914359229143657mer-m82291434622914366151-18.12
CAediting_77128chr1_85133844_+ENSG00000133216.15ENST00000400191hsa-miR-4423-3p22919318229193247mer-m82291930522919325140-13.9
CAediting_77128chr1_85133844_+ENSG00000133216.15ENST00000400191hsa-miR-4423-3p22920231229202377mer-m82292021822920238140-12.39
CAediting_77128chr1_85133844_+ENSG00000133216.15ENST00000400191hsa-miR-4423-3p22920831229208388mer-1a2292081822920838140-14.03
CAediting_1399425chr20_1392958_-ENSG00000133216.15ENST00000400191hsa-miR-6869-5p22916871229168777mer-m82291685522916878151-21.38
CAediting_1399425chr20_1392958_-ENSG00000133216.15ENST00000400191hsa-miR-6869-5p22919604229196107mer-m82291959022919611154-23.65
CAediting_1399425chr20_1392958_-ENSG00000133216.15ENST00000400191hsa-miR-6869-5p22919661229196688mer-1a2291964722919668151-23.07
CAediting_442554chr5_154685830_+ENSG00000133216.15ENST00000400191hsa-miR-130322917246229172538mer-1a2291723222917253164-23.68
CAediting_442554chr5_154685830_+ENSG00000133216.15ENST00000400191hsa-miR-130322913924229139307mer-m82291390922913931148-16.62
CAediting_604450chr7_133034877_-ENSG00000133216.15ENST00000400191hsa-miR-365422918036229180427mer-m82291802522918043140-16.72
CAediting_524911chr7_5495852_-ENSG00000133216.15ENST00000400191hsa-miR-589-3p22916728229167347mer-m82291671222916735157-29.03
CAediting_524911chr7_5495852_-ENSG00000133216.15ENST00000400191hsa-miR-589-3p22916809229168157mer-m82291679622916816166-29.42
CAediting_573000chr7_92204081_-ENSG00000133216.15ENST00000400191hsa-miR-1285-5p22914662229146687mer-m82291464822914669154-16.56
CAediting_573001chr7_92204086_-ENSG00000133216.15ENST00000400191hsa-miR-1285-5p22920878229208858mer-1a2292086522920885143-16.22
CAediting_442554chr5_154685830_+ENSG00000133216.15ENST00000374632hsa-miR-130322913924229139307mer-m82291390922913931148-16.62
CAediting_1054808chr15_66496985_-ENSG00000133216.15ENST00000374627hsa-miR-451222913245229132517mer-m82291323022913252146-22.2
CAediting_580943chr7_100356700_+ENSG00000133216.15ENST00000374627hsa-miR-6840-3p22913375229133817mer-m82291336122913382140-22.44
CAediting_468389chr6_31355314_-ENSG00000133216.15ENST00000400191hsa-miR-6891-5p22914720229147267mer-m82291471122914727149-23.05
CAediting_1524209chrX_134546392_-ENSG00000133216.15ENST00000400191hsa-miR-503-5p22916642229166487mer-m82291662422916649151-28.65

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_573000chr7_92204081_-ENSG00000133216.15ENST00000400191hsa-miR-1285-5p22914793229147997mer-m82291477922914800151-16.77
CAediting_573001chr7_92204086_-ENSG00000133216.15ENST00000400191hsa-miR-1285-5p22914793229147997mer-m82291477922914800151-16.77
CAediting_846604chr11_93733708_-ENSG00000133216.15ENST00000400191hsa-miR-1304-3p22915880229158878mer-1a2291586222915887147-22.75
CAediting_846604chr11_93733708_-ENSG00000133216.15ENST00000400191hsa-miR-1304-3p22917945229179517mer-m82291793422917952147-15.69
CAediting_86358chr1_109598906_+ENSG00000133216.15ENST00000400191hsa-miR-197-5p22918317229183237mer-m82291829822918324147-19.39
CAediting_1306324chr19_13836464_-ENSG00000133216.15ENST00000400191hsa-miR-27a-3p22915067229150737mer-m82291505522915074152-20.18
CAediting_1306323chr19_13836462_-ENSG00000133216.15ENST00000400191hsa-miR-27a-3p22915067229150737mer-m82291505522915074152-20.18
CAediting_1054808chr15_66496985_-ENSG00000133216.15ENST00000400191hsa-miR-451222918201229182077mer-m82291818822918208147-20.85
CAediting_1054808chr15_66496985_-ENSG00000133216.15ENST00000400191hsa-miR-451222919650229196567mer-m82291963322919657151-23.06
CAediting_1524209chrX_134546392_-ENSG00000133216.15ENST00000400191hsa-miR-503-5p22914028229140336mer2291401222914034151-23.61
CAediting_1524209chrX_134546392_-ENSG00000133216.15ENST00000400191hsa-miR-503-5p22916476229164827mer-m82291646122916483144-17.37
CAediting_1524209chrX_134546392_-ENSG00000133216.15ENST00000400191hsa-miR-503-5p22916555229165606mer2291653922916561141-14.45
CAediting_1524209chrX_134546392_-ENSG00000133216.15ENST00000400191hsa-miR-503-5p22918208229182136mer2291819022918214144-21.15
CAediting_1229414chr17_67471546_+ENSG00000133216.15ENST00000400191hsa-miR-548aa22914501229145077mer-m82291449022914514148-19.31
CAediting_1229415chr17_67471547_+ENSG00000133216.15ENST00000400191hsa-miR-548aa22914501229145077mer-m82291449022914514148-19.31
CAediting_1229413chr17_67471544_+ENSG00000133216.15ENST00000400191hsa-miR-548aa22914547229145537mer-m82291453022914554147-11.45
CAediting_1229414chr17_67471546_+ENSG00000133216.15ENST00000400191hsa-miR-548aa22914547229145537mer-m82291453022914554147-11.45
CAediting_1229415chr17_67471547_+ENSG00000133216.15ENST00000400191hsa-miR-548aa22914547229145537mer-m82291453022914554147-11.45
CAediting_524911chr7_5495852_-ENSG00000133216.15ENST00000400191hsa-miR-589-3p22916235229162417mer-m82291621922916242150-14.34
CAediting_748296chr10_51299626_+ENSG00000133216.15ENST00000400191hsa-miR-605-3p22920464229204707mer-m82292045222920471151-15.9
CAediting_980496chr14_31014685_-ENSG00000133216.15ENST00000400191hsa-miR-624-3p22917197229172037mer-m82291718422917204155-18.89
CAediting_1351755chr19_40282625_-ENSG00000133216.15ENST00000400191hsa-miR-64122920852229208587mer-m82292083422920859151-10.58
CAediting_580943chr7_100356700_+ENSG00000133216.15ENST00000400191hsa-miR-6840-3p22914239229142457mer-m82291422522914246140-19.69
CAediting_580943chr7_100356700_+ENSG00000133216.15ENST00000400191hsa-miR-6840-3p22918537229185437mer-m82291852322918544140-15.5
CAediting_580943chr7_100356700_+ENSG00000133216.15ENST00000400191hsa-miR-6840-3p22918970229189778mer-1a2291895622918977148-23.11
CAediting_580943chr7_100356700_+ENSG00000133216.15ENST00000400191hsa-miR-6840-3p22919018229190247mer-m82291900122919025153-28.49
CAediting_580943chr7_100356700_+ENSG00000133216.15ENST00000400191hsa-miR-6840-3p22920167229201737mer-m82292015022920174150-21.9
CAediting_1399425chr20_1392958_-ENSG00000133216.15ENST00000400191hsa-miR-6869-5p22917114229171196mer2291710022917120141-21.79
CAediting_468389chr6_31355314_-ENSG00000133216.15ENST00000400191hsa-miR-6891-5p22920100229201067mer-m82292008922920107145-18.65

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for EPHB2

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for EPHB2

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
STADCAediting_25005chr1_22744585_+..0.02660947293546310.304543158956636..
STADCAediting_25006chr1_22744594_+..0.01265937722957780.33117816195776..

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Relation with cancer stages for EPHB2

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for EPHB2

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for EPHB2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
EPHB2P29323DB12010FostamatinibEphrin type-B receptor 2 SmallMoleculeDrugapproved|investigational

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RelatedDiseases for EPHB2

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
EPHB2C0376358Malignant neoplasm of prostate2UNIPROT
EPHB2C0014474Ependymoma1CTD_human
EPHB2C0205769Myxopapillary ependymoma1CTD_human
EPHB2C0280788Anaplastic Ependymoma1CTD_human
EPHB2C0334578Papillary ependymoma1CTD_human
EPHB2C1384403Cellular Ependymoma1CTD_human
EPHB2C2931456Prostate cancer, familial1ORPHANET