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Editing gene: SUSD3 (CAeditome ID:203328)

Gene summary for SUSD3

Gene summary

Gene information	Gene symbol	SUSD3
	Gene ID	203328
	Gene name	sushi domain containing 3
	Synonyms	-
	Cytomap	9q22.31
	Type of gene	protein-coding
	Description	sushi domain-containing protein 3
	Modification date	20210518
	UniProtAcc	Q96L08
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
SUSD3	GO:0005886	Sushi domain-containing protein 3	24413080

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RNA A-to-I events for SUSD3

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000157303.9

RNA A-to-I editing events in Cancer.

CAediting_695267(93060649, +), CAediting_695268(93060652, +), CAediting_695269(93060653, +), CAediting_695270(93060697, +), CAediting_695271(93060705, +), CAediting_695272(93060715, +), CAediting_695273(93060776, +), CAediting_695274(93064080, +), CAediting_695275(93064097, +), CAediting_695276(93064174, +), CAediting_695277(93064187, +), CAediting_695278(93064197, +), CAediting_695279(93069811, +), CAediting_695280(93069905, +), CAediting_695281(93069959, +), CAediting_695282(93073430, +), CAediting_695283(93073455, +), CAediting_695284(93073509, +), CAediting_695285(93073510, +), CAediting_695286(93073522, +), CAediting_695287(93074152, +), CAediting_695288(93074189, +), CAediting_695289(93074190, +), CAediting_695290(93074211, +), CAediting_695291(93074242, +), CAediting_695292(93074245, +), CAediting_695293(93074268, +), CAediting_695294(93074271, +), CAediting_695295(93074280, +), CAediting_695296(93074287, +), CAediting_695297(93074310, +), CAediting_695298(93074315, +), CAediting_695299(93074319, +), CAediting_695300(93074355, +), CAediting_695301(93074385, +), CAediting_695302(93074419, +), CAediting_695303(93074652, +), CAediting_695304(93074695, +), CAediting_695305(93074732, +), CAediting_695306(93074744, +), CAediting_695307(93074754, +), CAediting_695308(93074780, +), CAediting_695309(93074789, +), CAediting_695310(93074795, +), CAediting_695311(93074798, +), CAediting_695312(93074848, +), CAediting_695313(93074851, +), CAediting_695314(93074874, +), CAediting_695315(93074888, +), CAediting_695316(93074889, +), CAediting_695317(93078978, +), CAediting_695318(93080066, +), CAediting_695319(93080072, +), CAediting_695320(93080157, +), CAediting_695321(93080158, +), CAediting_695322(93080240, +),

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RNA editing positional annotations for SUSD3 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_695267	chr9_93060649_+	intronic
CAediting_695268	chr9_93060652_+	intronic
CAediting_695269	chr9_93060653_+	intronic
CAediting_695270	chr9_93060697_+	intronic
CAediting_695271	chr9_93060705_+	intronic
CAediting_695272	chr9_93060715_+	intronic
CAediting_695273	chr9_93060776_+	intronic
CAediting_695274	chr9_93064080_+	intronic
CAediting_695275	chr9_93064097_+	intronic
CAediting_695276	chr9_93064174_+	intronic
CAediting_695277	chr9_93064187_+	intronic
CAediting_695278	chr9_93064197_+	intronic
CAediting_695279	chr9_93069811_+	intronic
CAediting_695280	chr9_93069905_+	intronic
CAediting_695281	chr9_93069959_+	intronic
CAediting_695282	chr9_93073430_+	intronic
CAediting_695283	chr9_93073455_+	intronic
CAediting_695284	chr9_93073509_+	intronic
CAediting_695285	chr9_93073510_+	intronic
CAediting_695286	chr9_93073522_+	intronic
CAediting_695287	chr9_93074152_+	intronic
CAediting_695288	chr9_93074189_+	intronic
CAediting_695289	chr9_93074190_+	intronic
CAediting_695290	chr9_93074211_+	intronic
CAediting_695291	chr9_93074242_+	intronic
CAediting_695292	chr9_93074245_+	intronic
CAediting_695293	chr9_93074268_+	intronic
CAediting_695294	chr9_93074271_+	intronic
CAediting_695295	chr9_93074280_+	intronic
CAediting_695296	chr9_93074287_+	intronic
CAediting_695297	chr9_93074310_+	intronic
CAediting_695298	chr9_93074315_+	intronic
CAediting_695299	chr9_93074319_+	intronic
CAediting_695300	chr9_93074355_+	intronic
CAediting_695301	chr9_93074385_+	intronic
CAediting_695302	chr9_93074419_+	intronic
CAediting_695303	chr9_93074652_+	intronic
CAediting_695304	chr9_93074695_+	intronic
CAediting_695305	chr9_93074732_+	intronic
CAediting_695306	chr9_93074744_+	intronic
CAediting_695307	chr9_93074754_+	intronic
CAediting_695308	chr9_93074780_+	intronic
CAediting_695309	chr9_93074789_+	intronic
CAediting_695310	chr9_93074795_+	intronic
CAediting_695311	chr9_93074798_+	intronic
CAediting_695312	chr9_93074848_+	intronic
CAediting_695313	chr9_93074851_+	intronic
CAediting_695314	chr9_93074874_+	intronic
CAediting_695315	chr9_93074888_+	intronic
CAediting_695316	chr9_93074889_+	intronic
CAediting_695317	chr9_93078978_+	intronic
CAediting_695318	chr9_93080066_+	intronic
CAediting_695319	chr9_93080072_+	intronic
CAediting_695320	chr9_93080157_+	intronic
CAediting_695321	chr9_93080158_+	intronic
CAediting_695322	chr9_93080240_+	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_695267	chr9_93060649_+	SINE	Alu	AluJr
CAediting_695268	chr9_93060652_+	SINE	Alu	AluJr
CAediting_695269	chr9_93060653_+	SINE	Alu	AluJr
CAediting_695270	chr9_93060697_+	SINE	Alu	AluJr
CAediting_695271	chr9_93060705_+	SINE	Alu	AluJr
CAediting_695272	chr9_93060715_+	SINE	Alu	AluJr
CAediting_695273	chr9_93060776_+	SINE	Alu	AluJr
CAediting_695274	chr9_93064080_+	SINE	Alu	AluSc
CAediting_695275	chr9_93064097_+	SINE	Alu	AluSc
CAediting_695276	chr9_93064174_+	SINE	Alu	AluSc
CAediting_695277	chr9_93064187_+	SINE	Alu	AluSc
CAediting_695278	chr9_93064197_+	SINE	Alu	AluSc
CAediting_695279	chr9_93069811_+	SINE	Alu	AluSz
CAediting_695280	chr9_93069905_+	SINE	Alu	AluSz
CAediting_695281	chr9_93069959_+	SINE	Alu	AluSz
CAediting_695282	chr9_93073430_+	SINE	Alu	AluY
CAediting_695283	chr9_93073455_+	SINE	Alu	AluY
CAediting_695284	chr9_93073509_+	SINE	Alu	AluY
CAediting_695285	chr9_93073510_+	SINE	Alu	AluY
CAediting_695286	chr9_93073522_+	SINE	Alu	AluY
CAediting_695288	chr9_93074189_+	SINE	Alu	AluSx3
CAediting_695289	chr9_93074190_+	SINE	Alu	AluSx3
CAediting_695290	chr9_93074211_+	SINE	Alu	AluSx3
CAediting_695291	chr9_93074242_+	SINE	Alu	AluSx3
CAediting_695292	chr9_93074245_+	SINE	Alu	AluSx3
CAediting_695293	chr9_93074268_+	SINE	Alu	AluSx3
CAediting_695294	chr9_93074271_+	SINE	Alu	AluSx3
CAediting_695295	chr9_93074280_+	SINE	Alu	AluSx3
CAediting_695296	chr9_93074287_+	SINE	Alu	AluSx3
CAediting_695297	chr9_93074310_+	SINE	Alu	AluSx3
CAediting_695298	chr9_93074315_+	SINE	Alu	AluSx3
CAediting_695299	chr9_93074319_+	SINE	Alu	AluSx3
CAediting_695300	chr9_93074355_+	SINE	Alu	AluSx3
CAediting_695301	chr9_93074385_+	SINE	Alu	AluSx3
CAediting_695302	chr9_93074419_+	SINE	Alu	AluSx3
CAediting_695303	chr9_93074652_+	SINE	Alu	AluSc5
CAediting_695304	chr9_93074695_+	SINE	Alu	AluSc5
CAediting_695305	chr9_93074732_+	SINE	Alu	AluSc5
CAediting_695306	chr9_93074744_+	SINE	Alu	AluSc5
CAediting_695307	chr9_93074754_+	SINE	Alu	AluSc5
CAediting_695308	chr9_93074780_+	SINE	Alu	AluSc5
CAediting_695309	chr9_93074789_+	SINE	Alu	AluSc5
CAediting_695310	chr9_93074795_+	SINE	Alu	AluSc5
CAediting_695311	chr9_93074798_+	SINE	Alu	AluSc5
CAediting_695312	chr9_93074848_+	SINE	Alu	AluSc5
CAediting_695313	chr9_93074851_+	SINE	Alu	AluSc5
CAediting_695314	chr9_93074874_+	SINE	Alu	AluSc5
CAediting_695315	chr9_93074888_+	SINE	Alu	AluSc5
CAediting_695316	chr9_93074889_+	SINE	Alu	AluSc5
CAediting_695317	chr9_93078978_+	SINE	Alu	AluY
CAediting_695318	chr9_93080066_+	SINE	Alu	AluSx
CAediting_695319	chr9_93080072_+	SINE	Alu	AluSx
CAediting_695320	chr9_93080157_+	SINE	Alu	AluSx
CAediting_695321	chr9_93080158_+	SINE	Alu	AluSx
CAediting_695322	chr9_93080240_+	SINE	Alu	AluSx

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RNA A-to-I editing events in the alternative splicing sites for SUSD3

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000157303.9.SUSD3.

Correlation between RNA A-to-I editing and PSI for ENSG00000157303.9.SUSD3.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SUSD3

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

BRCA.CAediting_695306.ENSG00000157303.SUSD3.png
Soverview

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Protein coding region RNA A-to-I editings for SUSD3

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for SUSD3

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1368054	chr19_46709310_-	ENSG00000157303.9	ENST00000617293	hsa-miR-320e	93084842	93084848	7mer-m8	93084832	93084849	146	-17.27
CAediting_77128	chr1_85133844_+	ENSG00000157303.9	ENST00000617293	hsa-miR-4423-3p	93084763	93084769	7mer-m8	93084750	93084770	150	-21.08
CAediting_1368054	chr19_46709310_-	ENSG00000157303.9	ENST00000375469	hsa-miR-320e	93084842	93084848	7mer-m8	93084832	93084849	146	-17.27
CAediting_77128	chr1_85133844_+	ENSG00000157303.9	ENST00000375469	hsa-miR-4423-3p	93084763	93084769	7mer-m8	93084750	93084770	150	-21.08
CAediting_1368054	chr19_46709310_-	ENSG00000157303.9	ENST00000471462	hsa-miR-320e	93084842	93084848	7mer-m8	93084832	93084849	146	-17.27
CAediting_77128	chr1_85133844_+	ENSG00000157303.9	ENST00000471462	hsa-miR-4423-3p	93084763	93084769	7mer-m8	93084750	93084770	150	-21.08

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for SUSD3

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for SUSD3

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for SUSD3

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for SUSD3

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for SUSD3

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for SUSD3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene