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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: CELSR2 (CAeditome ID:1952) |
Gene summary for CELSR2 |
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Gene information | Gene symbol | CELSR2 | Gene ID | 1952 |
Gene name | cadherin EGF LAG seven-pass G-type receptor 2 | |
Synonyms | ADGRC2|CDHF10|EGFL2|Flamingo1|MEGF3 | |
Cytomap | 1p13.3 | |
Type of gene | protein-coding | |
Description | cadherin EGF LAG seven-pass G-type receptor 2EGF-like protein 2EGF-like-domain, multiple 2adhesion G protein-coupled receptor C2cadherin family member 10cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)epidermal growth fa | |
Modification date | 20210531 | |
UniProtAcc | Q9HCU4 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for CELSR2 |
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CAediting_85717(109251361, +), CAediting_85718(109251362, +), CAediting_85719(109251388, +), CAediting_85720(109257113, +), CAediting_85721(109257216, +), CAediting_85722(109266990, +), |
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RNA editing positional annotations for CELSR2 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
CAediting_85719 | chr1_109251388_+ | nonsynonymous SNV | ENST00000271332.3 | c.A1309G | p.S437G | D | B | N |
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CAeditome ID | Position | Variant type |
CAediting_85717 | chr1_109251361_+ | exonic |
CAediting_85718 | chr1_109251362_+ | exonic |
CAediting_85719 | chr1_109251388_+ | exonic |
CAediting_85720 | chr1_109257113_+ | intronic |
CAediting_85721 | chr1_109257216_+ | intronic |
CAediting_85722 | chr1_109266990_+ | intronic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
CAediting_85720 | chr1_109257113_+ | SINE | Alu | AluJr |
CAediting_85721 | chr1_109257216_+ | SINE | Alu | AluJr |
CAediting_85722 | chr1_109266990_+ | SINE | Alu | AluSc |
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RNA A-to-I editing events in the alternative splicing sites for CELSR2 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CELSR2 |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for CELSR2 |
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The effects of the RNA editing to the miRNA binding sites for CELSR2 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for CELSR2 |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
ENST00000271332.3 | protein_coding | ![]() | ![]() |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
CAediting_85717 | ENST00000271332.3 | chr1_109251361_+ | -4385.90 | -4382.50 | -4387.80 |
CAediting_85718 | ENST00000271332.3 | chr1_109251362_+ | -4384.70 | -4382.50 | -4387.80 |
CAediting_85719 | ENST00000271332.3 | chr1_109251388_+ | -4382.40 | -4382.50 | -4387.80 |
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Relation with ADAR for CELSR2 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for CELSR2 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for CELSR2 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for CELSR2 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CELSR2 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
CELSR2 | C0014173 | Endometrial Hyperplasia | 1 | CTD_human |
CELSR2 | C0349578 | Complex Endometrial Hyperplasia | 1 | CTD_human |
CELSR2 | C0349579 | Atypical Endometrial Hyperplasia | 1 | CTD_human |
CELSR2 | C0456483 | Simple Endometrial Hyperplasia | 1 | CTD_human |