Home

Download

Statistics

Examples

Help

Contact

Editing gene: EEF1A1 (CAeditome ID:1915)

Gene summary for EEF1A1

Gene summary

Gene information	Gene symbol	EEF1A1
	Gene ID	1915
	Gene name	eukaryotic translation elongation factor 1 alpha 1
	Synonyms	CCS-3\|CCS3\|EE1A1\|EEF-1\|EEF1A\|EF-Tu\|EF1A\|GRAF-1EF\|LENG7\|PTI1\|eEF1A-1
	Cytomap	6q13
	Type of gene	protein-coding
	Description	elongation factor 1-alpha 1CTCL tumor antigenEF-1-alpha-1EF1a-like proteincervical cancer suppressor 3elongation factor 1 alpha subunitelongation factor Tuepididymis secretory sperm binding proteineukaryotic elongation factor 1 A-1eukaryotic tran
	Modification date	20210518
	UniProtAcc	P68104
	Context	- 31862491(Effects of eEF1A1 targeting by aptamer/siRNA in chronic lymphocytic leukaemia cells)

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
EEF1A1	GO:0000049	Elongation factor 1-alpha 1	12426392
EEF1A1	GO:0071364	Elongation factor 1-alpha 1	9852145
EEF1A1	GO:1900022	Elongation factor 1-alpha 1	18263879
EEF1A1	GO:0005634	Elongation factor 1-alpha 1	17177976
EEF1A1	GO:0005634	Elongation factor 1-alpha 1	8743958
EEF1A1	GO:0005634	Elongation factor 1-alpha 1	9852145
EEF1A1	GO:0005730	Elongation factor 1-alpha 1	9852145
EEF1A1	GO:0005737	Elongation factor 1-alpha 1	17177976
EEF1A1	GO:0005737	Elongation factor 1-alpha 1	17980171
EEF1A1	GO:0005737	Elongation factor 1-alpha 1	24209753
EEF1A1	GO:0005737	Elongation factor 1-alpha 1	8743958
EEF1A1	GO:0005737	Elongation factor 1-alpha 1	9852145
EEF1A1	GO:0005829	Elongation factor 1-alpha 1	19158340
EEF1A1	GO:0005886	Elongation factor 1-alpha 1	26497934
EEF1A1	GO:0030864	Elongation factor 1-alpha 1	19158340
EEF1A1	GO:0032587	Elongation factor 1-alpha 1	19158340

Top

RNA A-to-I events for EEF1A1

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000156508.16

RNA A-to-I editing events in Cancer.

CAediting_489739(73516349, -), CAediting_489740(73516352, -), CAediting_489741(73516358, -), CAediting_489742(73516361, -), CAediting_489743(73516370, -), CAediting_489744(73516371, -), CAediting_489745(73516405, -), CAediting_489746(73516407, -), CAediting_489747(73516418, -), CAediting_489748(73516427, -), CAediting_489749(73516437, -), CAediting_489750(73516446, -), CAediting_489751(73516447, -), CAediting_489752(73516461, -), CAediting_489753(73516472, -), CAediting_489754(73516484, -), CAediting_489755(73516487, -), CAediting_489756(73516488, -), CAediting_489757(73516496, -), CAediting_489758(73516513, -), CAediting_489759(73516545, -), CAediting_489760(73516558, -), CAediting_489761(73516579, -), CAediting_489762(73516585, -), CAediting_489763(73516586, -), CAediting_489764(73516718, -), CAediting_489765(73516739, -), CAediting_489766(73522708, -), CAediting_489767(73522744, -), CAediting_489768(73522750, -), CAediting_489769(73523324, -), CAediting_489770(73523337, -), CAediting_489771(73523417, -), CAediting_489772(73523418, -), CAediting_489773(73523422, -),

Top

RNA editing positional annotations for EEF1A1 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_489739	chr6_73516349_-	UTR3
CAediting_489740	chr6_73516352_-	UTR3
CAediting_489741	chr6_73516358_-	UTR3
CAediting_489742	chr6_73516361_-	UTR3
CAediting_489743	chr6_73516370_-	UTR3
CAediting_489744	chr6_73516371_-	UTR3
CAediting_489745	chr6_73516405_-	UTR3
CAediting_489746	chr6_73516407_-	UTR3
CAediting_489747	chr6_73516418_-	UTR3
CAediting_489748	chr6_73516427_-	UTR3
CAediting_489749	chr6_73516437_-	UTR3
CAediting_489750	chr6_73516446_-	UTR3
CAediting_489751	chr6_73516447_-	UTR3
CAediting_489752	chr6_73516461_-	UTR3
CAediting_489753	chr6_73516472_-	UTR3
CAediting_489754	chr6_73516484_-	UTR3
CAediting_489755	chr6_73516487_-	UTR3
CAediting_489756	chr6_73516488_-	UTR3
CAediting_489757	chr6_73516496_-	UTR3
CAediting_489758	chr6_73516513_-	UTR3
CAediting_489759	chr6_73516545_-	UTR3
CAediting_489760	chr6_73516558_-	UTR3
CAediting_489761	chr6_73516579_-	UTR3
CAediting_489762	chr6_73516585_-	UTR3
CAediting_489763	chr6_73516586_-	UTR3
CAediting_489764	chr6_73516718_-	UTR3
CAediting_489765	chr6_73516739_-	UTR3
CAediting_489766	chr6_73522708_-	intronic
CAediting_489767	chr6_73522744_-	intronic
CAediting_489768	chr6_73522750_-	intronic
CAediting_489769	chr6_73523324_-	intronic
CAediting_489770	chr6_73523337_-	intronic
CAediting_489771	chr6_73523417_-	intronic
CAediting_489772	chr6_73523418_-	intronic
CAediting_489773	chr6_73523422_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_489739	chr6_73516349_-	SINE	Alu	AluSp
CAediting_489740	chr6_73516352_-	SINE	Alu	AluSp
CAediting_489741	chr6_73516358_-	SINE	Alu	AluSp
CAediting_489742	chr6_73516361_-	SINE	Alu	AluSp
CAediting_489743	chr6_73516370_-	SINE	Alu	AluSp
CAediting_489744	chr6_73516371_-	SINE	Alu	AluSp
CAediting_489745	chr6_73516405_-	SINE	Alu	AluSp
CAediting_489746	chr6_73516407_-	SINE	Alu	AluSp
CAediting_489747	chr6_73516418_-	SINE	Alu	AluSp
CAediting_489748	chr6_73516427_-	SINE	Alu	AluSp
CAediting_489749	chr6_73516437_-	SINE	Alu	AluSp
CAediting_489750	chr6_73516446_-	SINE	Alu	AluSp
CAediting_489751	chr6_73516447_-	SINE	Alu	AluSp
CAediting_489752	chr6_73516461_-	SINE	Alu	AluSp
CAediting_489753	chr6_73516472_-	SINE	Alu	AluSp
CAediting_489754	chr6_73516484_-	SINE	Alu	AluSp
CAediting_489755	chr6_73516487_-	SINE	Alu	AluSp
CAediting_489756	chr6_73516488_-	SINE	Alu	AluSp
CAediting_489757	chr6_73516496_-	SINE	Alu	AluSp
CAediting_489758	chr6_73516513_-	SINE	Alu	AluSp
CAediting_489759	chr6_73516545_-	SINE	Alu	AluSp
CAediting_489760	chr6_73516558_-	SINE	Alu	AluSp
CAediting_489761	chr6_73516579_-	SINE	Alu	AluSp
CAediting_489762	chr6_73516585_-	SINE	Alu	AluSp
CAediting_489763	chr6_73516586_-	SINE	Alu	AluSp
CAediting_489764	chr6_73516718_-	SINE	Alu	Alu
CAediting_489765	chr6_73516739_-	SINE	Alu	Alu
CAediting_489766	chr6_73522708_-	SINE	Alu	AluSz
CAediting_489767	chr6_73522744_-	SINE	Alu	AluSz
CAediting_489768	chr6_73522750_-	SINE	Alu	AluSz
CAediting_489769	chr6_73523324_-	SINE	Alu	AluSz
CAediting_489770	chr6_73523337_-	SINE	Alu	AluSz
CAediting_489771	chr6_73523417_-	SINE	Alu	AluSz
CAediting_489772	chr6_73523418_-	SINE	Alu	AluSz
CAediting_489773	chr6_73523422_-	SINE	Alu	AluSz

Top

RNA A-to-I editing events in the alternative splicing sites for EEF1A1

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
IR	CAediting_489753	chr6_73516472_-	73516468:73516490	3SS	0+2i	CCAAGTAGCTGGGATTACAGGCA	-5.43	CCAAGTAGCTGGGATTACGGGCA	-13.38
IR	CAediting_489754	chr6_73516484_-	73516468:73516490	3SS	0+14i	CCAAGTAGCTGGGATTACAGGCA	-5.43	CCAAGTGGCTGGGATTACAGGCA	-1.67
IR	CAediting_489755	chr6_73516487_-	73516468:73516490	3SS	0+17i	CCAAGTAGCTGGGATTACAGGCA	-5.43	CCAGGTAGCTGGGATTACAGGCA	-4.85
IR	CAediting_489756	chr6_73516488_-	73516468:73516490	3SS	0+18i	CCAAGTAGCTGGGATTACAGGCA	-5.43	CCGAGTAGCTGGGATTACAGGCA	-5.3
IR	CAediting_489765	chr6_73516739_-	73516731:73516739	5SS	3+0i	AGGCATGAG	-23.6	GGGCATGAG	-27.46

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000156508.16.EEF1A1.

Correlation between RNA A-to-I editing and PSI for ENSG00000156508.16.EEF1A1.

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for EEF1A1

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Top

Protein coding region RNA A-to-I editings for EEF1A1

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

Top

The effects of the RNA editing to the miRNA binding sites for EEF1A1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_489763	chr6_73516586_-	ENSG00000156508.16	ENST00000316292	hsa-miR-3613-3p	73516585	73516592	8mer-1a	73516585	73516608	150.00	-8.03
CAediting_489763	chr6_73516586_-	ENSG00000156508.16	ENST00000316292	hsa-miR-371b-5p	73516583	73516590	8mer-1a	73516583	73516604	146.00	-7.79
CAediting_489763	chr6_73516586_-	ENSG00000156508.16	ENST00000316292	hsa-miR-373-5p	73516583	73516590	8mer-1a	73516583	73516604	140.00	-8.35
CAediting_489763	chr6_73516586_-	ENSG00000156508.16	ENST00000316292	hsa-miR-616-5p	73516583	73516590	8mer-1a	73516583	73516604	140.00	-5.71
CAediting_489739	chr6_73516349_-	ENSG00000156508.16	ENST00000316292	hsa-miR-4641	73516347	73516353	7mer-m8	73516346	73516370	160.00	-19.74
CAediting_489739	chr6_73516349_-	ENSG00000156508.16	ENST00000316292	hsa-miR-663b	73516344	73516350	7mer-m8	73516343	73516360	150.00	-30.90
CAediting_489739	chr6_73516349_-	ENSG00000156508.16	ENST00000316292	hsa-miR-6872-3p	73516349	73516355	7mer-m8	73516348	73516368	145.00	-23.89
CAediting_489741	chr6_73516358_-	ENSG00000156508.16	ENST00000316292	hsa-miR-106a-3p	73516356	73516361	6mer	73516355	73516376	141.00	-21.49
CAediting_489742	chr6_73516361_-	ENSG00000156508.16	ENST00000316292	hsa-miR-4764-3p	73516358	73516364	7mer-m8	73516357	73516378	140.00	-12.68
CAediting_489742	chr6_73516361_-	ENSG00000156508.16	ENST00000316292	hsa-miR-508-5p	73516360	73516366	7mer-m8	73516359	73516381	140.00	-18.00
CAediting_489742	chr6_73516361_-	ENSG00000156508.16	ENST00000316292	hsa-miR-766-3p	73516361	73516367	7mer-m8	73516360	73516381	143.00	-15.60
CAediting_489745	chr6_73516405_-	ENSG00000156508.16	ENST00000316292	hsa-miR-28-5p	73516400	73516406	7mer-m8	73516399	73516419	143.00	-18.76
CAediting_489745	chr6_73516405_-	ENSG00000156508.16	ENST00000316292	hsa-miR-3139	73516400	73516406	7mer-m8	73516399	73516421	157.00	-23.72
CAediting_489745	chr6_73516405_-	ENSG00000156508.16	ENST00000316292	hsa-miR-4538	73516403	73516408	6mer	73516402	73516424	143.00	-25.65
CAediting_489745	chr6_73516405_-	ENSG00000156508.16	ENST00000316292	hsa-miR-708-5p	73516400	73516406	7mer-m8	73516399	73516420	154.00	-20.89
CAediting_489749	chr6_73516437_-	ENSG00000156508.16	ENST00000316292	hsa-miR-6771-3p	73516432	73516438	7mer-m8	73516431	73516452	153.00	-14.92
CAediting_489754	chr6_73516484_-	ENSG00000156508.16	ENST00000316292	hsa-miR-3614-5p	73516484	73516490	7mer-m8	73516483	73516507	154.00	-24.19
CAediting_489754	chr6_73516484_-	ENSG00000156508.16	ENST00000316292	hsa-miR-4691-3p	73516480	73516486	7mer-m8	73516479	73516505	152.00	-25.75
CAediting_489755	chr6_73516487_-	ENSG00000156508.16	ENST00000316292	hsa-miR-6852-5p	73516486	73516491	6mer	73516485	73516505	144.00	-23.69
CAediting_489756	chr6_73516488_-	ENSG00000156508.16	ENST00000316292	hsa-miR-6771-5p	73516487	73516493	7mer-m8	73516486	73516505	148.00	-29.19
CAediting_489759	chr6_73516545_-	ENSG00000156508.16	ENST00000316292	hsa-miR-7161-3p	73516541	73516547	7mer-m8	73516540	73516565	159.00	-15.75
CAediting_489760	chr6_73516558_-	ENSG00000156508.16	ENST00000316292	hsa-miR-7975	73516557	73516562	6mer	73516556	73516573	143.00	-19.92
CAediting_489764	chr6_73516718_-	ENSG00000156508.16	ENST00000316292	hsa-miR-4645-5p	73516718	73516724	7mer-m8	73516717	73516736	141.00	-14.50
CAediting_489764	chr6_73516718_-	ENSG00000156508.16	ENST00000316292	hsa-miR-4673	73516718	73516724	7mer-m8	73516717	73516739	141.00	-19.35
CAediting_489764	chr6_73516718_-	ENSG00000156508.16	ENST00000316292	hsa-miR-4755-3p	73516717	73516723	7mer-m8	73516716	73516737	144.00	-18.40
CAediting_489744	chr6_73516371_-	ENSG00000156508.16	ENST00000316292	hsa-miR-3059-3p	73516369	73516375	7mer-m8	73516368	73516391	147.00	-18.54
CAediting_489744	chr6_73516371_-	ENSG00000156508.16	ENST00000316292	hsa-miR-5684	73516368	73516374	7mer-m8	73516367	73516389	141.00	-15.29
CAediting_489752	chr6_73516461_-	ENSG00000156508.16	ENST00000316292	hsa-miR-34a-3p	73516458	73516464	7mer-m8	73516457	73516477	152.00	-14.64
CAediting_489752	chr6_73516461_-	ENSG00000156508.16	ENST00000316292	hsa-miR-3617-3p	73516459	73516465	7mer-m8	73516458	73516484	153.00	-20.20

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_489755	chr6_73516487_-	ENSG00000156508.16	ENST00000316292	hsa-miR-12126	73516484	73516491	8mer-1a	73516484	73516507	147	-12.83
CAediting_489756	chr6_73516488_-	ENSG00000156508.16	ENST00000316292	hsa-miR-12126	73516484	73516491	8mer-1a	73516484	73516507	147	-12.83
CAediting_489756	chr6_73516488_-	ENSG00000156508.16	ENST00000316292	hsa-miR-1273h-5p	73516487	73516494	8mer-1a	73516487	73516508	148	-17.65
CAediting_489760	chr6_73516558_-	ENSG00000156508.16	ENST00000316292	hsa-miR-1287-3p	73516557	73516564	8mer-1a	73516557	73516578	142	-13.32
CAediting_489756	chr6_73516488_-	ENSG00000156508.16	ENST00000316292	hsa-miR-30b-3p	73516487	73516494	8mer-1a	73516487	73516508	155	-17.36
CAediting_489756	chr6_73516488_-	ENSG00000156508.16	ENST00000316292	hsa-miR-3689a-3p	73516487	73516494	8mer-1a	73516487	73516507	148	-19.19
CAediting_489756	chr6_73516488_-	ENSG00000156508.16	ENST00000316292	hsa-miR-3689b-3p	73516487	73516494	8mer-1a	73516487	73516507	148	-19.92
CAediting_489756	chr6_73516488_-	ENSG00000156508.16	ENST00000316292	hsa-miR-3689c	73516487	73516494	8mer-1a	73516487	73516507	148	-19.92
CAediting_489747	chr6_73516418_-	ENSG00000156508.16	ENST00000316292	hsa-miR-4293	73516414	73516420	7mer-m8	73516413	73516429	146	-21.19
CAediting_489750	chr6_73516446_-	ENSG00000156508.16	ENST00000316292	hsa-miR-4477a	73516444	73516449	6mer	73516443	73516464	142	-15.05
CAediting_489751	chr6_73516447_-	ENSG00000156508.16	ENST00000316292	hsa-miR-4477a	73516444	73516449	6mer	73516443	73516464	142	-15.05
CAediting_489750	chr6_73516446_-	ENSG00000156508.16	ENST00000316292	hsa-miR-4477a	73516444	73516449	6mer	73516443	73516464	142	-15.05
CAediting_489751	chr6_73516447_-	ENSG00000156508.16	ENST00000316292	hsa-miR-4477a	73516444	73516449	6mer	73516443	73516464	142	-15.05
CAediting_489757	chr6_73516496_-	ENSG00000156508.16	ENST00000316292	hsa-miR-4478	73516492	73516498	7mer-m8	73516491	73516506	149	-24.29
CAediting_489757	chr6_73516496_-	ENSG00000156508.16	ENST00000316292	hsa-miR-485-5p	73516491	73516497	7mer-m8	73516490	73516511	149	-18.64
CAediting_489754	chr6_73516484_-	ENSG00000156508.16	ENST00000316292	hsa-miR-5690	73516480	73516486	7mer-m8	73516479	73516499	145	-16.74
CAediting_489752	chr6_73516461_-	ENSG00000156508.16	ENST00000316292	hsa-miR-585-5p	73516460	73516467	8mer-1a	73516460	73516483	147	-18.47
CAediting_489749	chr6_73516437_-	ENSG00000156508.16	ENST00000316292	hsa-miR-6072	73516435	73516441	7mer-m8	73516434	73516456	143	-15.67
CAediting_489765	chr6_73516739_-	ENSG00000156508.16	ENST00000316292	hsa-miR-6514-3p	73516735	73516741	7mer-m8	73516734	73516754	155	-20.04
CAediting_489756	chr6_73516488_-	ENSG00000156508.16	ENST00000316292	hsa-miR-6779-5p	73516487	73516494	8mer-1a	73516487	73516505	148	-20.91
CAediting_489756	chr6_73516488_-	ENSG00000156508.16	ENST00000316292	hsa-miR-6780a-5p	73516487	73516494	8mer-1a	73516487	73516510	150	-25
CAediting_489739	chr6_73516349_-	ENSG00000156508.16	ENST00000316292	hsa-miR-6847-3p	73516347	73516353	7mer-m8	73516346	73516369	148	-20.19
CAediting_489740	chr6_73516352_-	ENSG00000156508.16	ENST00000316292	hsa-miR-6847-3p	73516347	73516353	7mer-m8	73516346	73516369	148	-20.19
CAediting_489749	chr6_73516437_-	ENSG00000156508.16	ENST00000316292	hsa-miR-6891-3p	73516435	73516441	7mer-m8	73516434	73516454	146	-12.88
CAediting_489755	chr6_73516487_-	ENSG00000156508.16	ENST00000316292	hsa-miR-887-5p	73516487	73516493	7mer-m8	73516486	73516505	143	-19.81
CAediting_489756	chr6_73516488_-	ENSG00000156508.16	ENST00000316292	hsa-miR-887-5p	73516487	73516493	7mer-m8	73516486	73516505	143	-19.81

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1229413	chr17_67471544_+	ENSG00000156508.16	ENST00000316292	hsa-miR-548aa	73517016	73517023	8mer-1a	73517016	73517039	148	-13.04
CAediting_524911	chr7_5495852_-	ENSG00000156508.16	ENST00000316292	hsa-miR-589-3p	73516130	73516137	8mer-1a	73516130	73516153	149	-16.79
CAediting_468389	chr6_31355314_-	ENSG00000156508.16	ENST00000316292	hsa-miR-6891-5p	73516526	73516531	6mer	73516522	73516540	157	-22.31
CAediting_468389	chr6_31355314_-	ENSG00000156508.16	ENST00000316292	hsa-miR-6891-5p	73516523	73516529	7mer-m8	73516522	73516540	157	-22.31

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1229413	chr17_67471544_+	ENSG00000156508.16	ENST00000316292	hsa-miR-548aa	73516601	73516607	7mer-m8	73516600	73516621	142	-9.7
CAediting_1229414	chr17_67471546_+	ENSG00000156508.16	ENST00000316292	hsa-miR-548aa	73516601	73516607	7mer-m8	73516600	73516621	142	-9.7
CAediting_1229415	chr17_67471547_+	ENSG00000156508.16	ENST00000316292	hsa-miR-548aa	73516601	73516607	7mer-m8	73516600	73516621	142	-9.7
CAediting_1229413	chr17_67471544_+	ENSG00000156508.16	ENST00000316292	hsa-miR-548aa	73517636	73517642	7mer-m8	73517635	73517657	146	-9.07
CAediting_1229414	chr17_67471546_+	ENSG00000156508.16	ENST00000316292	hsa-miR-548aa	73517636	73517642	7mer-m8	73517635	73517657	146	-9.07
CAediting_1229415	chr17_67471547_+	ENSG00000156508.16	ENST00000316292	hsa-miR-548aa	73517636	73517642	7mer-m8	73517635	73517657	146	-9.07

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for EEF1A1

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000316292.12	protein_coding
ENST00000610520.3	protein_coding
ENST00000615060.3	protein_coding

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_489739	ENST00000316292.12	chr6_73516349_-	-1422.00	-1417.90	-1443.20
CAediting_489740	ENST00000316292.12	chr6_73516352_-	-1417.50	-1417.90	-1443.20
CAediting_489741	ENST00000316292.12	chr6_73516358_-	-1417.90	-1417.90	-1443.20
CAediting_489742	ENST00000316292.12	chr6_73516361_-	-1418.90	-1417.90	-1443.20
CAediting_489743	ENST00000316292.12	chr6_73516370_-	-1422.10	-1417.90	-1443.20
CAediting_489744	ENST00000316292.12	chr6_73516371_-	-1418.20	-1417.90	-1443.20
CAediting_489745	ENST00000316292.12	chr6_73516405_-	-1418.20	-1417.90	-1443.20
CAediting_489746	ENST00000316292.12	chr6_73516407_-	-1418.60	-1417.90	-1443.20
CAediting_489747	ENST00000316292.12	chr6_73516418_-	-1421.50	-1417.90	-1443.20
CAediting_489748	ENST00000316292.12	chr6_73516427_-	-1420.20	-1417.90	-1443.20
CAediting_489749	ENST00000316292.12	chr6_73516437_-	-1423.30	-1417.90	-1443.20
CAediting_489750	ENST00000316292.12	chr6_73516446_-	-1419.10	-1417.90	-1443.20
CAediting_489751	ENST00000316292.12	chr6_73516447_-	-1422.80	-1417.90	-1443.20
CAediting_489752	ENST00000316292.12	chr6_73516461_-	-1418.30	-1417.90	-1443.20
CAediting_489753	ENST00000316292.12	chr6_73516472_-	-1418.30	-1417.90	-1443.20
CAediting_489754	ENST00000316292.12	chr6_73516484_-	-1421.10	-1417.90	-1443.20
CAediting_489755	ENST00000316292.12	chr6_73516487_-	-1421.50	-1417.90	-1443.20
CAediting_489756	ENST00000316292.12	chr6_73516488_-	-1418.30	-1417.90	-1443.20
CAediting_489757	ENST00000316292.12	chr6_73516496_-	-1418.80	-1417.90	-1443.20
CAediting_489758	ENST00000316292.12	chr6_73516513_-	-1417.60	-1417.90	-1443.20
CAediting_489759	ENST00000316292.12	chr6_73516545_-	-1417.90	-1417.90	-1443.20
CAediting_489760	ENST00000316292.12	chr6_73516558_-	-1421.00	-1417.90	-1443.20
CAediting_489761	ENST00000316292.12	chr6_73516579_-	-1416.90	-1417.90	-1443.20
CAediting_489762	ENST00000316292.12	chr6_73516585_-	-1420.20	-1417.90	-1443.20
CAediting_489763	ENST00000316292.12	chr6_73516586_-	-1418.30	-1417.90	-1443.20
CAediting_489764	ENST00000316292.12	chr6_73516718_-	-1418.90	-1417.90	-1443.20
CAediting_489765	ENST00000316292.12	chr6_73516739_-	-1417.20	-1417.90	-1443.20
CAediting_489739	ENST00000610520.3	chr6_73516349_-	-989.00	-984.90	-1007.60
CAediting_489740	ENST00000610520.3	chr6_73516352_-	-984.50	-984.90	-1007.60
CAediting_489741	ENST00000610520.3	chr6_73516358_-	-984.70	-984.90	-1007.60
CAediting_489742	ENST00000610520.3	chr6_73516361_-	-987.50	-984.90	-1007.60
CAediting_489743	ENST00000610520.3	chr6_73516370_-	-987.40	-984.90	-1007.60
CAediting_489744	ENST00000610520.3	chr6_73516371_-	-985.40	-984.90	-1007.60
CAediting_489745	ENST00000610520.3	chr6_73516405_-	-984.80	-984.90	-1007.60
CAediting_489746	ENST00000610520.3	chr6_73516407_-	-984.60	-984.90	-1007.60
CAediting_489747	ENST00000610520.3	chr6_73516418_-	-984.60	-984.90	-1007.60
CAediting_489748	ENST00000610520.3	chr6_73516427_-	-987.20	-984.90	-1007.60
CAediting_489749	ENST00000610520.3	chr6_73516437_-	-990.30	-984.90	-1007.60
CAediting_489750	ENST00000610520.3	chr6_73516446_-	-984.90	-984.90	-1007.60
CAediting_489751	ENST00000610520.3	chr6_73516447_-	-989.80	-984.90	-1007.60
CAediting_489752	ENST00000610520.3	chr6_73516461_-	-983.90	-984.90	-1007.60
CAediting_489753	ENST00000610520.3	chr6_73516472_-	-985.30	-984.90	-1007.60
CAediting_489754	ENST00000610520.3	chr6_73516484_-	-983.60	-984.90	-1007.60
CAediting_489755	ENST00000610520.3	chr6_73516487_-	-984.60	-984.90	-1007.60
CAediting_489756	ENST00000610520.3	chr6_73516488_-	-985.30	-984.90	-1007.60
CAediting_489757	ENST00000610520.3	chr6_73516496_-	-984.90	-984.90	-1007.60
CAediting_489758	ENST00000610520.3	chr6_73516513_-	-984.60	-984.90	-1007.60
CAediting_489759	ENST00000610520.3	chr6_73516545_-	-984.90	-984.90	-1007.60
CAediting_489760	ENST00000610520.3	chr6_73516558_-	-988.00	-984.90	-1007.60
CAediting_489761	ENST00000610520.3	chr6_73516579_-	-983.90	-984.90	-1007.60
CAediting_489762	ENST00000610520.3	chr6_73516585_-	-987.20	-984.90	-1007.60
CAediting_489763	ENST00000610520.3	chr6_73516586_-	-985.30	-984.90	-1007.60
CAediting_489764	ENST00000610520.3	chr6_73516718_-	-985.90	-984.90	-1007.60
CAediting_489765	ENST00000610520.3	chr6_73516739_-	-984.20	-984.90	-1007.60
CAediting_489739	ENST00000615060.3	chr6_73516349_-	-1003.80	-999.70	-1020.40
CAediting_489740	ENST00000615060.3	chr6_73516352_-	-999.30	-999.70	-1020.40
CAediting_489741	ENST00000615060.3	chr6_73516358_-	-999.70	-999.70	-1020.40
CAediting_489742	ENST00000615060.3	chr6_73516361_-	-1000.30	-999.70	-1020.40
CAediting_489743	ENST00000615060.3	chr6_73516370_-	-1000.80	-999.70	-1020.40
CAediting_489744	ENST00000615060.3	chr6_73516371_-	-999.40	-999.70	-1020.40
CAediting_489745	ENST00000615060.3	chr6_73516405_-	-1000.00	-999.70	-1020.40
CAediting_489746	ENST00000615060.3	chr6_73516407_-	-999.70	-999.70	-1020.40
CAediting_489747	ENST00000615060.3	chr6_73516418_-	-999.90	-999.70	-1020.40
CAediting_489748	ENST00000615060.3	chr6_73516427_-	-999.30	-999.70	-1020.40
CAediting_489749	ENST00000615060.3	chr6_73516437_-	-999.60	-999.70	-1020.40
CAediting_489750	ENST00000615060.3	chr6_73516446_-	-999.70	-999.70	-1020.40
CAediting_489751	ENST00000615060.3	chr6_73516447_-	-999.70	-999.70	-1020.40
CAediting_489752	ENST00000615060.3	chr6_73516461_-	-1000.10	-999.70	-1020.40
CAediting_489753	ENST00000615060.3	chr6_73516472_-	-1000.00	-999.70	-1020.40
CAediting_489754	ENST00000615060.3	chr6_73516484_-	-1001.20	-999.70	-1020.40
CAediting_489755	ENST00000615060.3	chr6_73516487_-	-1003.30	-999.70	-1020.40
CAediting_489756	ENST00000615060.3	chr6_73516488_-	-999.00	-999.70	-1020.40
CAediting_489757	ENST00000615060.3	chr6_73516496_-	-999.40	-999.70	-1020.40
CAediting_489758	ENST00000615060.3	chr6_73516513_-	-999.40	-999.70	-1020.40
CAediting_489759	ENST00000615060.3	chr6_73516545_-	-999.70	-999.70	-1020.40
CAediting_489760	ENST00000615060.3	chr6_73516558_-	-1002.80	-999.70	-1020.40
CAediting_489761	ENST00000615060.3	chr6_73516579_-	-998.70	-999.70	-1020.40
CAediting_489762	ENST00000615060.3	chr6_73516585_-	-999.40	-999.70	-1020.40
CAediting_489763	ENST00000615060.3	chr6_73516586_-	-999.80	-999.70	-1020.40
CAediting_489764	ENST00000615060.3	chr6_73516718_-	-1000.70	-999.70	-1020.40
CAediting_489765	ENST00000615060.3	chr6_73516739_-	-999.00	-999.70	-1020.40

Top

Relation with ADAR for EEF1A1

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

Top

Relation with cancer stages for EEF1A1

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

Top

Relation with survival for EEF1A1

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

Top

RelatedDrugs for EEF1A1

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
EEF1A1	P68104	DB14548	Zinc sulfate, unspecified form	Elongation factor 1-alpha 1	SmallMoleculeDrug	approved\|experimental
EEF1A1	P68104	DB01593	Zinc	Elongation factor 1-alpha 1	SmallMoleculeDrug	approved\|investigational
EEF1A1	P68104	DB09130	Copper	Elongation factor 1-alpha 1	SmallMoleculeDrug	approved\|investigational
EEF1A1	P68104	DB14487	Zinc acetate	Elongation factor 1-alpha 1	SmallMoleculeDrug	approved\|investigational
EEF1A1	P68104	DB14533	Zinc chloride	Elongation factor 1-alpha 1	SmallMoleculeDrug	approved\|investigational

Top

RelatedDiseases for EEF1A1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
EEF1A1	C0007097	Carcinoma	1	CTD_human
EEF1A1	C0024623	Malignant neoplasm of stomach	1	CTD_human
EEF1A1	C0024667	Animal Mammary Neoplasms	1	CTD_human
EEF1A1	C0024668	Mammary Neoplasms, Experimental	1	CTD_human
EEF1A1	C0038356	Stomach Neoplasms	1	CTD_human
EEF1A1	C0205696	Anaplastic carcinoma	1	CTD_human
EEF1A1	C0205697	Carcinoma, Spindle-Cell	1	CTD_human
EEF1A1	C0205698	Undifferentiated carcinoma	1	CTD_human
EEF1A1	C0205699	Carcinomatosis	1	CTD_human
EEF1A1	C1257925	Mammary Carcinoma, Animal	1	CTD_human
EEF1A1	C1708349	Hereditary Diffuse Gastric Cancer	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene