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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: DYRK1A (CAeditome ID:1859)

Gene summary for DYRK1A

check button Gene summary
Gene informationGene symbol

DYRK1A

Gene ID

1859

Gene namedual specificity tyrosine phosphorylation regulated kinase 1A
SynonymsDYRK|DYRK1|HP86|MNB|MNBH|MRD7
Cytomap

21q22.13

Type of geneprotein-coding
Descriptiondual specificity tyrosine-phosphorylation-regulated kinase 1AMNB/DYRK protein kinasedual specificity YAK1-related kinasedual specificity tyrosine-(Y)-phosphorylation regulated kinase 1Amnb protein kinase homolog hp86protein kinase minibrain homologs
Modification date20210518
UniProtAcc

Q13627

Context- 34033760(DYRK1A is required for maintenance of cancer stemness, contributing to tumorigenic potential in oral/oropharyngeal squamous cell carcinoma)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
DYRK1A

GO:0018108

Dual specificity tyrosine-phosphorylation-regulated kinase 1A

9748265

DYRK1A

GO:0005856

Dual specificity tyrosine-phosphorylation-regulated kinase 1A

24327345

DYRK1A

GO:0004715

Dual specificity tyrosine-phosphorylation-regulated kinase 1A

9748265

DYRK1A

GO:0033120

Dual specificity tyrosine-phosphorylation-regulated kinase 1A

28377597

DYRK1A

GO:0038083

Dual specificity tyrosine-phosphorylation-regulated kinase 1A

24327345

DYRK1A

GO:0005634

Dual specificity tyrosine-phosphorylation-regulated kinase 1A

15694837

DYRK1A

GO:0005634

Dual specificity tyrosine-phosphorylation-regulated kinase 1A

23415227

DYRK1A

GO:0005737

Dual specificity tyrosine-phosphorylation-regulated kinase 1A

15694837


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RNA A-to-I events for DYRK1A

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000157540.18

check button RNA A-to-I editing events in Cancer.
CAediting_1452164(37372182, +), CAediting_1452165(37372189, +), CAediting_1452166(37372210, +), CAediting_1452167(37372224, +), CAediting_1452168(37372234, +), CAediting_1452169(37372244, +), CAediting_1452170(37372315, +), CAediting_1452171(37372321, +), CAediting_1452172(37372327, +), CAediting_1452173(37374632, +), CAediting_1452174(37374633, +), CAediting_1452175(37375587, +), CAediting_1452176(37375589, +), CAediting_1452177(37375606, +), CAediting_1452178(37375643, +), CAediting_1452179(37375655, +), CAediting_1452180(37375667, +), CAediting_1452181(37375687, +), CAediting_1452182(37375690, +), CAediting_1452183(37375691, +), CAediting_1452184(37375701, +), CAediting_1452185(37375710, +), CAediting_1452186(37375724, +), CAediting_1452187(37375736, +), CAediting_1452188(37375783, +), CAediting_1452189(37375792, +), CAediting_1452190(37376232, +), CAediting_1452191(37376238, +), CAediting_1452192(37376254, +), CAediting_1452193(37376255, +), CAediting_1452194(37376290, +), CAediting_1452195(37376298, +), CAediting_1452196(37376324, +), CAediting_1452197(37376330, +), CAediting_1452198(37376338, +), CAediting_1452199(37376349, +), CAediting_1452200(37376366, +), CAediting_1452201(37376388, +), CAediting_1452202(37376409, +), CAediting_1452203(37376415, +), CAediting_1452204(37376430, +), CAediting_1452205(37376438, +), CAediting_1452206(37376450, +), CAediting_1452207(37377237, +), CAediting_1452208(37377285, +), CAediting_1452209(37377393, +), CAediting_1452210(37377519, +), CAediting_1452211(37377569, +), CAediting_1452212(37377603, +), CAediting_1452213(37378373, +), CAediting_1452214(37378374, +), CAediting_1452215(37378380, +), CAediting_1452216(37378516, +), CAediting_1452217(37390051, +), CAediting_1452218(37400867, +), CAediting_1452219(37400890, +), CAediting_1452220(37400991, +), CAediting_1452221(37400993, +), CAediting_1452222(37401015, +), CAediting_1452223(37401017, +), CAediting_1452224(37401023, +), CAediting_1452225(37401029, +), CAediting_1452226(37401033, +), CAediting_1452227(37401040, +), CAediting_1452228(37401064, +), CAediting_1452229(37401129, +), CAediting_1452230(37401204, +), CAediting_1452231(37401583, +), CAediting_1452232(37401586, +), CAediting_1452233(37401612, +), CAediting_1452234(37401624, +), CAediting_1452235(37401663, +), CAediting_1452236(37401666, +), CAediting_1452237(37401744, +), CAediting_1452238(37402892, +), CAediting_1452239(37402909, +), CAediting_1452240(37402947, +), CAediting_1452241(37403017, +), CAediting_1452242(37403706, +), CAediting_1452243(37406486, +), CAediting_1452244(37406534, +), CAediting_1452245(37406537, +), CAediting_1452246(37406539, +), CAediting_1452247(37406542, +), CAediting_1452248(37406552, +), CAediting_1452249(37406596, +), CAediting_1452250(37410544, +), CAediting_1452251(37410556, +), CAediting_1452252(37410564, +), CAediting_1452253(37410602, +), CAediting_1452254(37410607, +), CAediting_1452255(37410613, +), CAediting_1452256(37410631, +), CAediting_1452257(37410645, +), CAediting_1452258(37410657, +), CAediting_1452259(37410667, +), CAediting_1452260(37410922, +), CAediting_1452261(37410928, +), CAediting_1452262(37410929, +), CAediting_1452263(37410941, +), CAediting_1452264(37411102, +), CAediting_1452265(37411103, +), CAediting_1452266(37411146, +), CAediting_1452267(37411193, +), CAediting_1452268(37411194, +), CAediting_1452269(37411195, +), CAediting_1452270(37411196, +), CAediting_1452271(37411199, +), CAediting_1452272(37411213, +), CAediting_1452273(37411233, +), CAediting_1452274(37411236, +), CAediting_1452275(37411241, +), CAediting_1452276(37411258, +), CAediting_1452277(37411262, +), CAediting_1452278(37411269, +), CAediting_1452279(37411277, +), CAediting_1452280(37411281, +), CAediting_1452281(37411311, +), CAediting_1452282(37415701, +), CAediting_1452283(37426647, +), CAediting_1452284(37426655, +), CAediting_1452285(37426656, +), CAediting_1452286(37426805, +), CAediting_1452287(37426840, +), CAediting_1452288(37427130, +), CAediting_1452289(37427131, +), CAediting_1452290(37427135, +), CAediting_1452291(37427161, +), CAediting_1452292(37427210, +), CAediting_1452293(37427212, +), CAediting_1452294(37427238, +), CAediting_1452295(37427241, +), CAediting_1452296(37427257, +), CAediting_1452297(37427377, +), CAediting_1452298(37427386, +), CAediting_1452299(37427398, +), CAediting_1452300(37465635, +), CAediting_1452301(37467279, +), CAediting_1452302(37467360, +), CAediting_1452303(37467451, +), CAediting_1452304(37467466, +), CAediting_1452305(37468344, +), CAediting_1452306(37481581, +), CAediting_1452307(37481585, +), CAediting_1452308(37481658, +), CAediting_1452309(37481742, +), CAediting_1452310(37481744, +), CAediting_1452311(37494801, +),

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RNA editing positional annotations for DYRK1A using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1452164chr21_37372182_+ncRNA_intronic
CAediting_1452165chr21_37372189_+ncRNA_intronic
CAediting_1452166chr21_37372210_+ncRNA_intronic
CAediting_1452167chr21_37372224_+ncRNA_intronic
CAediting_1452168chr21_37372234_+ncRNA_intronic
CAediting_1452169chr21_37372244_+ncRNA_intronic
CAediting_1452170chr21_37372315_+ncRNA_intronic
CAediting_1452171chr21_37372321_+ncRNA_intronic
CAediting_1452172chr21_37372327_+ncRNA_intronic
CAediting_1452173chr21_37374632_+ncRNA_intronic
CAediting_1452174chr21_37374633_+ncRNA_intronic
CAediting_1452175chr21_37375587_+ncRNA_intronic
CAediting_1452176chr21_37375589_+ncRNA_intronic
CAediting_1452177chr21_37375606_+ncRNA_intronic
CAediting_1452178chr21_37375643_+ncRNA_intronic
CAediting_1452179chr21_37375655_+ncRNA_intronic
CAediting_1452180chr21_37375667_+ncRNA_intronic
CAediting_1452181chr21_37375687_+ncRNA_intronic
CAediting_1452182chr21_37375690_+ncRNA_intronic
CAediting_1452183chr21_37375691_+ncRNA_intronic
CAediting_1452184chr21_37375701_+ncRNA_intronic
CAediting_1452185chr21_37375710_+ncRNA_intronic
CAediting_1452186chr21_37375724_+ncRNA_intronic
CAediting_1452187chr21_37375736_+ncRNA_intronic
CAediting_1452188chr21_37375783_+ncRNA_intronic
CAediting_1452189chr21_37375792_+ncRNA_intronic
CAediting_1452190chr21_37376232_+ncRNA_intronic
CAediting_1452191chr21_37376238_+ncRNA_intronic
CAediting_1452192chr21_37376254_+ncRNA_intronic
CAediting_1452193chr21_37376255_+ncRNA_intronic
CAediting_1452194chr21_37376290_+ncRNA_intronic
CAediting_1452195chr21_37376298_+ncRNA_intronic
CAediting_1452196chr21_37376324_+ncRNA_intronic
CAediting_1452197chr21_37376330_+ncRNA_intronic
CAediting_1452198chr21_37376338_+ncRNA_intronic
CAediting_1452199chr21_37376349_+ncRNA_intronic
CAediting_1452200chr21_37376366_+ncRNA_intronic
CAediting_1452201chr21_37376388_+ncRNA_intronic
CAediting_1452202chr21_37376409_+ncRNA_intronic
CAediting_1452203chr21_37376415_+ncRNA_intronic
CAediting_1452204chr21_37376430_+ncRNA_intronic
CAediting_1452205chr21_37376438_+ncRNA_intronic
CAediting_1452206chr21_37376450_+ncRNA_intronic
CAediting_1452207chr21_37377237_+ncRNA_intronic
CAediting_1452208chr21_37377285_+ncRNA_intronic
CAediting_1452209chr21_37377393_+ncRNA_intronic
CAediting_1452210chr21_37377519_+ncRNA_intronic
CAediting_1452211chr21_37377569_+ncRNA_intronic
CAediting_1452212chr21_37377603_+ncRNA_intronic
CAediting_1452213chr21_37378373_+ncRNA_intronic
CAediting_1452214chr21_37378374_+ncRNA_intronic
CAediting_1452215chr21_37378380_+ncRNA_intronic
CAediting_1452216chr21_37378516_+ncRNA_intronic
CAediting_1452217chr21_37390051_+ncRNA_intronic
CAediting_1452218chr21_37400867_+ncRNA_intronic
CAediting_1452219chr21_37400890_+ncRNA_intronic
CAediting_1452220chr21_37400991_+ncRNA_intronic
CAediting_1452221chr21_37400993_+ncRNA_intronic
CAediting_1452222chr21_37401015_+ncRNA_intronic
CAediting_1452223chr21_37401017_+ncRNA_intronic
CAediting_1452224chr21_37401023_+ncRNA_intronic
CAediting_1452225chr21_37401029_+ncRNA_intronic
CAediting_1452226chr21_37401033_+ncRNA_intronic
CAediting_1452227chr21_37401040_+ncRNA_intronic
CAediting_1452228chr21_37401064_+ncRNA_intronic
CAediting_1452229chr21_37401129_+ncRNA_intronic
CAediting_1452230chr21_37401204_+ncRNA_intronic
CAediting_1452231chr21_37401583_+ncRNA_intronic
CAediting_1452232chr21_37401586_+ncRNA_intronic
CAediting_1452233chr21_37401612_+ncRNA_intronic
CAediting_1452234chr21_37401624_+ncRNA_intronic
CAediting_1452235chr21_37401663_+ncRNA_intronic
CAediting_1452236chr21_37401666_+ncRNA_intronic
CAediting_1452237chr21_37401744_+ncRNA_intronic
CAediting_1452238chr21_37402892_+ncRNA_intronic
CAediting_1452239chr21_37402909_+ncRNA_intronic
CAediting_1452240chr21_37402947_+ncRNA_intronic
CAediting_1452241chr21_37403017_+ncRNA_intronic
CAediting_1452242chr21_37403706_+ncRNA_intronic
CAediting_1452243chr21_37406486_+ncRNA_intronic
CAediting_1452244chr21_37406534_+ncRNA_intronic
CAediting_1452245chr21_37406537_+ncRNA_intronic
CAediting_1452246chr21_37406539_+ncRNA_intronic
CAediting_1452247chr21_37406542_+ncRNA_intronic
CAediting_1452248chr21_37406552_+ncRNA_intronic
CAediting_1452249chr21_37406596_+ncRNA_intronic
CAediting_1452250chr21_37410544_+ncRNA_intronic
CAediting_1452251chr21_37410556_+ncRNA_intronic
CAediting_1452252chr21_37410564_+ncRNA_intronic
CAediting_1452253chr21_37410602_+ncRNA_intronic
CAediting_1452254chr21_37410607_+ncRNA_intronic
CAediting_1452255chr21_37410613_+ncRNA_intronic
CAediting_1452256chr21_37410631_+ncRNA_intronic
CAediting_1452257chr21_37410645_+ncRNA_intronic
CAediting_1452258chr21_37410657_+ncRNA_intronic
CAediting_1452259chr21_37410667_+ncRNA_intronic
CAediting_1452260chr21_37410922_+ncRNA_intronic
CAediting_1452261chr21_37410928_+ncRNA_intronic
CAediting_1452262chr21_37410929_+ncRNA_intronic
CAediting_1452263chr21_37410941_+ncRNA_intronic
CAediting_1452264chr21_37411102_+ncRNA_intronic
CAediting_1452265chr21_37411103_+ncRNA_intronic
CAediting_1452266chr21_37411146_+ncRNA_intronic
CAediting_1452267chr21_37411193_+ncRNA_intronic
CAediting_1452268chr21_37411194_+ncRNA_intronic
CAediting_1452269chr21_37411195_+ncRNA_intronic
CAediting_1452270chr21_37411196_+ncRNA_intronic
CAediting_1452271chr21_37411199_+ncRNA_intronic
CAediting_1452272chr21_37411213_+ncRNA_intronic
CAediting_1452273chr21_37411233_+ncRNA_intronic
CAediting_1452274chr21_37411236_+ncRNA_intronic
CAediting_1452275chr21_37411241_+ncRNA_intronic
CAediting_1452276chr21_37411258_+ncRNA_intronic
CAediting_1452277chr21_37411262_+ncRNA_intronic
CAediting_1452278chr21_37411269_+ncRNA_intronic
CAediting_1452279chr21_37411277_+ncRNA_intronic
CAediting_1452280chr21_37411281_+ncRNA_intronic
CAediting_1452281chr21_37411311_+ncRNA_intronic
CAediting_1452282chr21_37415701_+ncRNA_intronic
CAediting_1452283chr21_37426647_+ncRNA_intronic
CAediting_1452284chr21_37426655_+ncRNA_intronic
CAediting_1452285chr21_37426656_+ncRNA_intronic
CAediting_1452286chr21_37426805_+ncRNA_intronic
CAediting_1452287chr21_37426840_+ncRNA_intronic
CAediting_1452288chr21_37427130_+ncRNA_intronic
CAediting_1452289chr21_37427131_+ncRNA_intronic
CAediting_1452290chr21_37427135_+ncRNA_intronic
CAediting_1452291chr21_37427161_+ncRNA_intronic
CAediting_1452292chr21_37427210_+ncRNA_intronic
CAediting_1452293chr21_37427212_+ncRNA_intronic
CAediting_1452294chr21_37427238_+ncRNA_intronic
CAediting_1452295chr21_37427241_+ncRNA_intronic
CAediting_1452296chr21_37427257_+ncRNA_intronic
CAediting_1452297chr21_37427377_+ncRNA_intronic
CAediting_1452298chr21_37427386_+ncRNA_intronic
CAediting_1452299chr21_37427398_+ncRNA_intronic
CAediting_1452300chr21_37465635_+ncRNA_intronic
CAediting_1452301chr21_37467279_+ncRNA_intronic
CAediting_1452302chr21_37467360_+ncRNA_intronic
CAediting_1452303chr21_37467451_+ncRNA_intronic
CAediting_1452304chr21_37467466_+ncRNA_intronic
CAediting_1452305chr21_37468344_+ncRNA_intronic
CAediting_1452306chr21_37481581_+ncRNA_intronic
CAediting_1452307chr21_37481585_+ncRNA_intronic
CAediting_1452308chr21_37481658_+ncRNA_intronic
CAediting_1452309chr21_37481742_+ncRNA_intronic
CAediting_1452310chr21_37481744_+ncRNA_intronic
CAediting_1452311chr21_37494801_+intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1452164chr21_37372182_+SINEAluAluJb
CAediting_1452165chr21_37372189_+SINEAluAluJb
CAediting_1452166chr21_37372210_+SINEAluAluJb
CAediting_1452167chr21_37372224_+SINEAluAluJb
CAediting_1452168chr21_37372234_+SINEAluAluJb
CAediting_1452169chr21_37372244_+SINEAluAluJb
CAediting_1452170chr21_37372315_+SINEAluAluJb
CAediting_1452171chr21_37372321_+SINEAluAluJb
CAediting_1452172chr21_37372327_+SINEAluAluJb
CAediting_1452173chr21_37374632_+SINEAluAluYm1
CAediting_1452174chr21_37374633_+SINEAluAluYm1
CAediting_1452175chr21_37375587_+SINEAluAluSq2
CAediting_1452176chr21_37375589_+SINEAluAluSq2
CAediting_1452177chr21_37375606_+SINEAluAluSq2
CAediting_1452178chr21_37375643_+SINEAluAluSq2
CAediting_1452179chr21_37375655_+SINEAluAluSq2
CAediting_1452180chr21_37375667_+SINEAluAluSq2
CAediting_1452181chr21_37375687_+SINEAluAluSq2
CAediting_1452182chr21_37375690_+SINEAluAluSq2
CAediting_1452183chr21_37375691_+SINEAluAluSq2
CAediting_1452184chr21_37375701_+SINEAluAluSq2
CAediting_1452185chr21_37375710_+SINEAluAluSq2
CAediting_1452186chr21_37375724_+SINEAluAluSq2
CAediting_1452187chr21_37375736_+SINEAluAluSq2
CAediting_1452188chr21_37375783_+SINEAluAluSq2
CAediting_1452189chr21_37375792_+SINEAluAluSq2
CAediting_1452190chr21_37376232_+SINEAluAluSg4
CAediting_1452191chr21_37376238_+SINEAluAluSg4
CAediting_1452192chr21_37376254_+SINEAluAluSg4
CAediting_1452193chr21_37376255_+SINEAluAluSg4
CAediting_1452194chr21_37376290_+SINEAluAluSg4
CAediting_1452195chr21_37376298_+SINEAluAluSg4
CAediting_1452196chr21_37376324_+SINEAluAluSg4
CAediting_1452197chr21_37376330_+SINEAluAluSg4
CAediting_1452198chr21_37376338_+SINEAluAluSg4
CAediting_1452199chr21_37376349_+SINEAluAluSg4
CAediting_1452200chr21_37376366_+SINEAluAluSg4
CAediting_1452201chr21_37376388_+SINEAluAluSg4
CAediting_1452202chr21_37376409_+SINEAluAluSg4
CAediting_1452203chr21_37376415_+SINEAluAluSg4
CAediting_1452204chr21_37376430_+SINEAluAluSg4
CAediting_1452205chr21_37376438_+SINEAluAluSg4
CAediting_1452206chr21_37376450_+SINEAluAluSg4
CAediting_1452207chr21_37377237_+SINEAluAluYm1
CAediting_1452208chr21_37377285_+SINEAluAluYm1
CAediting_1452209chr21_37377393_+SINEAluAluYm1
CAediting_1452210chr21_37377519_+SINEAluAluJr
CAediting_1452211chr21_37377569_+SINEAluAluJr
CAediting_1452212chr21_37377603_+SINEAluAluJr
CAediting_1452213chr21_37378373_+SINEAluAluSp
CAediting_1452214chr21_37378374_+SINEAluAluSp
CAediting_1452215chr21_37378380_+SINEAluAluSp
CAediting_1452216chr21_37378516_+SINEAluAluSp
CAediting_1452217chr21_37390051_+SINEAluAluJo
CAediting_1452218chr21_37400867_+SINEAluAluSz
CAediting_1452219chr21_37400890_+SINEAluAluSz
CAediting_1452220chr21_37400991_+SINEAluAluSz
CAediting_1452221chr21_37400993_+SINEAluAluSz
CAediting_1452222chr21_37401015_+SINEAluAluSz
CAediting_1452223chr21_37401017_+SINEAluAluSz
CAediting_1452224chr21_37401023_+SINEAluAluSz
CAediting_1452225chr21_37401029_+SINEAluAluSz
CAediting_1452226chr21_37401033_+SINEAluAluSz
CAediting_1452227chr21_37401040_+SINEAluAluSz
CAediting_1452228chr21_37401064_+SINEAluAluSz
CAediting_1452229chr21_37401129_+SINEAluAluSz
CAediting_1452231chr21_37401583_+SINEAluAluSq2
CAediting_1452232chr21_37401586_+SINEAluAluSq2
CAediting_1452233chr21_37401612_+SINEAluAluSq2
CAediting_1452234chr21_37401624_+SINEAluAluSq2
CAediting_1452235chr21_37401663_+SINEAluAluSq2
CAediting_1452236chr21_37401666_+SINEAluAluSq2
CAediting_1452237chr21_37401744_+SINEAluAluSq2
CAediting_1452238chr21_37402892_+SINEAluAluSx
CAediting_1452239chr21_37402909_+SINEAluAluSx
CAediting_1452240chr21_37402947_+SINEAluAluSx
CAediting_1452241chr21_37403017_+SINEAluAluSx
CAediting_1452242chr21_37403706_+SINEAluAluJr
CAediting_1452243chr21_37406486_+SINEAluAluSz6
CAediting_1452244chr21_37406534_+SINEAluAluSz6
CAediting_1452245chr21_37406537_+SINEAluAluSz6
CAediting_1452246chr21_37406539_+SINEAluAluSz6
CAediting_1452247chr21_37406542_+SINEAluAluSz6
CAediting_1452248chr21_37406552_+SINEAluAluSz6
CAediting_1452249chr21_37406596_+SINEAluAluSz6
CAediting_1452250chr21_37410544_+SINEAluAluJr
CAediting_1452251chr21_37410556_+SINEAluAluJr
CAediting_1452252chr21_37410564_+SINEAluAluJr
CAediting_1452253chr21_37410602_+SINEAluAluJr
CAediting_1452254chr21_37410607_+SINEAluAluJr
CAediting_1452255chr21_37410613_+SINEAluAluJr
CAediting_1452256chr21_37410631_+SINEAluAluJr
CAediting_1452257chr21_37410645_+SINEAluAluJr
CAediting_1452258chr21_37410657_+SINEAluAluJr
CAediting_1452259chr21_37410667_+SINEAluAluJr
CAediting_1452260chr21_37410922_+SINEAluAluSz
CAediting_1452261chr21_37410928_+SINEAluAluSz
CAediting_1452262chr21_37410929_+SINEAluAluSz
CAediting_1452263chr21_37410941_+SINEAluAluSz
CAediting_1452264chr21_37411102_+SINEAluAluSx3
CAediting_1452265chr21_37411103_+SINEAluAluSx3
CAediting_1452266chr21_37411146_+SINEAluAluSx3
CAediting_1452267chr21_37411193_+SINEAluAluSx3
CAediting_1452268chr21_37411194_+SINEAluAluSx3
CAediting_1452269chr21_37411195_+SINEAluAluSx3
CAediting_1452270chr21_37411196_+SINEAluAluSx3
CAediting_1452271chr21_37411199_+SINEAluAluSx3
CAediting_1452272chr21_37411213_+SINEAluAluSx3
CAediting_1452273chr21_37411233_+SINEAluAluSx3
CAediting_1452274chr21_37411236_+SINEAluAluSx3
CAediting_1452275chr21_37411241_+SINEAluAluSx3
CAediting_1452276chr21_37411258_+SINEAluAluSx3
CAediting_1452277chr21_37411262_+SINEAluAluSx3
CAediting_1452278chr21_37411269_+SINEAluAluSx3
CAediting_1452279chr21_37411277_+SINEAluAluSx3
CAediting_1452280chr21_37411281_+SINEAluAluSx3
CAediting_1452281chr21_37411311_+SINEAluAluSx3
CAediting_1452282chr21_37415701_+SINEAluAluJb
CAediting_1452283chr21_37426647_+SINEAluAluYk3
CAediting_1452284chr21_37426655_+SINEAluAluYk3
CAediting_1452285chr21_37426656_+SINEAluAluYk3
CAediting_1452286chr21_37426805_+SINEAluAluYk3
CAediting_1452287chr21_37426840_+SINEAluAluYk3
CAediting_1452288chr21_37427130_+SINEAluAluJr
CAediting_1452289chr21_37427131_+SINEAluAluJr
CAediting_1452290chr21_37427135_+SINEAluAluJr
CAediting_1452291chr21_37427161_+SINEAluAluJr
CAediting_1452292chr21_37427210_+SINEAluAluJr
CAediting_1452293chr21_37427212_+SINEAluAluJr
CAediting_1452294chr21_37427238_+SINEAluAluJr
CAediting_1452295chr21_37427241_+SINEAluAluJr
CAediting_1452296chr21_37427257_+SINEAluAluJr
CAediting_1452297chr21_37427377_+SINEAluAluJr
CAediting_1452298chr21_37427386_+SINEAluAluJr
CAediting_1452299chr21_37427398_+SINEAluAluJr
CAediting_1452300chr21_37465635_+SINEAluAluSx1
CAediting_1452301chr21_37467279_+SINEAluAluJb
CAediting_1452302chr21_37467360_+SINEAluAluJb
CAediting_1452303chr21_37467451_+SINEAluAluJb
CAediting_1452304chr21_37467466_+SINEAluAluJb
CAediting_1452305chr21_37468344_+SINEAluAluJo
CAediting_1452306chr21_37481581_+SINEAluAluSx
CAediting_1452307chr21_37481585_+SINEAluAluSx
CAediting_1452308chr21_37481658_+SINEAluAluSx
CAediting_1452309chr21_37481742_+SINEAluFLAM_C
CAediting_1452310chr21_37481744_+SINEAluFLAM_C
CAediting_1452311chr21_37494801_+SINEAluAluSz

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RNA A-to-I editing events in the alternative splicing sites for DYRK1A

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESCAediting_1452251chr21_37410556_+37410549:374105713SS0+13iCACTTTCACTTTGTCACCCAGGC-8.51CACTTTCGCTTTGTCACCCAGGC-8.39
MEX_2CAediting_1452251chr21_37410556_+37410549:374105713SS0+13iCACTTTCACTTTGTCACCCAGGC-8.51CACTTTCGCTTTGTCACCCAGGC-8.39
ESCAediting_1452252chr21_37410564_+37410549:374105713SS0+5iCACTTTCACTTTGTCACCCAGGC-8.51CACTTTCACTTTGTCGCCCAGGC-9.6
MEX_2CAediting_1452252chr21_37410564_+37410549:374105713SS0+5iCACTTTCACTTTGTCACCCAGGC-8.51CACTTTCACTTTGTCGCCCAGGC-9.6

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000157540.18.DYRK1A.
boxplot

check button Correlation between RNA A-to-I editing and PSI for ENSG00000157540.18.DYRK1A.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for DYRK1A

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for DYRK1A

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for DYRK1A

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_688080chr9_63819626_+ENSG00000157540.18ENST00000338785hsa-miR-4477b37512216375122227mer-m83751220237512223146-10.9
CAediting_1229414chr17_67471546_+ENSG00000157540.18ENST00000338785hsa-miR-548aa37513341375133477mer-m83751332137513348161-21.18
CAediting_1229414chr17_67471546_+ENSG00000157540.18ENST00000338785hsa-miR-548aa37512847375128537mer-m83751282137512854154-18.58
CAediting_1399425chr20_1392958_-ENSG00000157540.18ENST00000338785hsa-miR-6869-5p37512160375121678mer-1a3751214637512167154-23.06
CAediting_228905chr2_188297554_+ENSG00000157540.18ENST00000338785hsa-miR-561-3p37513166375131716mer3751315237513172144-19.32
CAediting_442554chr5_154685830_+ENSG00000157540.18ENST00000338785hsa-miR-130337512141375121477mer-m83751212337512148141-18.96
CAediting_414656chr5_72878640_+ENSG00000157540.18ENST00000338785hsa-miR-4804-3p37514684375146907mer-m83751467137514691140-10.41
CAediting_1524209chrX_134546392_-ENSG00000157540.18ENST00000338785hsa-miR-503-5p37514273375142797mer-m83751425837514280145-17.87

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_86358chr1_109598906_+ENSG00000157540.18ENST00000338785hsa-miR-197-5p37512159375121668mer-1a3751214537512166155-21.87
CAediting_604450chr7_133034877_-ENSG00000157540.18ENST00000338785hsa-miR-365437514962375149687mer-m83751495137514969140-12.49
CAediting_228905chr2_188297554_+ENSG00000157540.18ENST00000338785hsa-miR-561-3p37514635375146417mer-m83751462237514642141-5.18
CAediting_524911chr7_5495852_-ENSG00000157540.18ENST00000338785hsa-miR-589-3p37512971375129777mer-m83751295537512978150-12.18

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for DYRK1A

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for DYRK1A

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
STADCAediting_1452264chr21_37411102_+0.001520441771758380.413870470840018....
STADCAediting_1452265chr21_37411103_+0.01362306596143750.343393441100189....
STADCAediting_1452273chr21_37411233_+0.02071398959472290.31411720389453....

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Relation with cancer stages for DYRK1A

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for DYRK1A

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for DYRK1A

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
DYRK1AQ13627DB12010FostamatinibDual specificity tyrosine-phosphorylation-regulated kinase 1A SmallMoleculeDrugapproved|investigational

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RelatedDiseases for DYRK1A

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
DYRK1AC1535926Neurodevelopmental Disorders2CTD_human
DYRK1AC3279839MENTAL RETARDATION, AUTOSOMAL DOMINANT 72CTD_human;GENOMICS_ENGLAND
DYRK1AC0014544Epilepsy1CTD_human
DYRK1AC0025958Microcephaly1GENOMICS_ENGLAND
DYRK1AC0086237Epilepsy, Cryptogenic1CTD_human
DYRK1AC0236018Aura1CTD_human
DYRK1AC0751111Awakening Epilepsy1CTD_human