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Editing gene: DPH1 (CAeditome ID:1801)

Gene summary for DPH1

Gene summary

Gene information	Gene symbol	DPH1
	Gene ID	1801
	Gene name	diphthamide biosynthesis 1
	Synonyms	DEDSSH\|DPH2L\|DPH2L1\|OVCA1
	Cytomap	17p13.3
	Type of gene	protein-coding
	Description	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1DPH-like 1DPH1 homologDPH2-like 1S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1candidate tumor suppressor in ovarian cancer 1diphthamide biosynthesis protein 1diphtham
	Modification date	20210518
	UniProtAcc	Q9BZG8
	Context	- 29145210(Diphthamide Biosynthesis 1 is a Novel Oncogene in Colorectal Cancer Cells and is Regulated by MiR-218-5p)

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
DPH1	GO:0005654	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1	0000052
DPH1	GO:0030054	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1	0000052

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RNA A-to-I events for DPH1

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000108963.16

RNA A-to-I editing events in Cancer.

CAediting_1152117(2036964, +), CAediting_1152118(2036965, +), CAediting_1152119(2036967, +), CAediting_1152120(2037408, +), CAediting_1152121(2037616, +), CAediting_1152122(2037836, +), CAediting_1152123(2037905, +), CAediting_1152124(2037999, +), CAediting_1152125(2038036, +), CAediting_1152126(2038038, +), CAediting_1152127(2038046, +), CAediting_1152128(2038054, +), CAediting_1152129(2038055, +), CAediting_1152130(2038060, +), CAediting_1152131(2038061, +), CAediting_1152132(2038071, +), CAediting_1152133(2038076, +), CAediting_1152134(2038077, +), CAediting_1152135(2038081, +), CAediting_1152136(2038086, +), CAediting_1152137(2038100, +), CAediting_1152138(2038109, +), CAediting_1152139(2038111, +), CAediting_1152140(2038114, +), CAediting_1152141(2038123, +), CAediting_1152142(2038128, +), CAediting_1152143(2038133, +), CAediting_1152144(2038134, +), CAediting_1152145(2038150, +), CAediting_1152146(2038151, +), CAediting_1152147(2038157, +), CAediting_1152148(2038158, +), CAediting_1152149(2038159, +), CAediting_1152150(2038166, +), CAediting_1152151(2038167, +), CAediting_1152152(2038168, +), CAediting_1152153(2038169, +), CAediting_1152154(2038187, +), CAediting_1152155(2038189, +), CAediting_1152156(2038196, +), CAediting_1152157(2038204, +), CAediting_1152158(2038210, +), CAediting_1152159(2038218, +), CAediting_1152160(2038221, +), CAediting_1152161(2038227, +), CAediting_1152162(2038232, +), CAediting_1152163(2038234, +), CAediting_1152164(2038245, +), CAediting_1152165(2038253, +), CAediting_1152166(2038266, +), CAediting_1152167(2038270, +), CAediting_1152168(2038274, +), CAediting_1152169(2038290, +), CAediting_1152170(2038299, +), CAediting_1152171(2038301, +), CAediting_1152172(2038303, +), CAediting_1152173(2038306, +), CAediting_1152174(2038307, +), CAediting_1152175(2038309, +), CAediting_1152176(2038333, +), CAediting_1152177(2038558, +), CAediting_1152178(2039081, +), CAediting_1152179(2039083, +), CAediting_1152180(2039087, +), CAediting_1152181(2039126, +), CAediting_1152182(2039141, +), CAediting_1152183(2039162, +), CAediting_1152184(2039179, +), CAediting_1152185(2039188, +), CAediting_1152186(2039203, +), CAediting_1152187(2039217, +), CAediting_1152188(2039223, +), CAediting_1152189(2039227, +), CAediting_1152190(2039228, +), CAediting_1152191(2039243, +), CAediting_1152192(2039260, +), CAediting_1152193(2039268, +), CAediting_1152194(2039321, +), CAediting_1152195(2039322, +), CAediting_1152196(2039323, +), CAediting_1152197(2039335, +), CAediting_1152198(2039344, +), CAediting_1152199(2039397, +), CAediting_1152200(2039399, +), CAediting_1152201(2039442, +), CAediting_1152202(2039452, +), CAediting_1152203(2039458, +), CAediting_1152204(2039495, +), CAediting_1152205(2039504, +), CAediting_1152206(2039517, +), CAediting_1152207(2039519, +), CAediting_1152208(2039559, +), CAediting_1152209(2039584, +), CAediting_1152210(2039591, +), CAediting_1152211(2039638, +), CAediting_1152212(2039639, +), CAediting_1152213(2039651, +), CAediting_1152214(2039653, +), CAediting_1152215(2039660, +),

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RNA editing positional annotations for DPH1 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1152117	chr17_2036964_+	ncRNA_exonic
CAediting_1152118	chr17_2036965_+	ncRNA_exonic
CAediting_1152119	chr17_2036967_+	ncRNA_exonic
CAediting_1152120	chr17_2037408_+	ncRNA_intronic
CAediting_1152121	chr17_2037616_+	ncRNA_intronic
CAediting_1152122	chr17_2037836_+	ncRNA_intronic
CAediting_1152123	chr17_2037905_+	ncRNA_intronic
CAediting_1152124	chr17_2037999_+	ncRNA_intronic
CAediting_1152125	chr17_2038036_+	ncRNA_intronic
CAediting_1152126	chr17_2038038_+	ncRNA_intronic
CAediting_1152127	chr17_2038046_+	ncRNA_intronic
CAediting_1152128	chr17_2038054_+	ncRNA_intronic
CAediting_1152129	chr17_2038055_+	ncRNA_intronic
CAediting_1152130	chr17_2038060_+	ncRNA_intronic
CAediting_1152131	chr17_2038061_+	ncRNA_intronic
CAediting_1152132	chr17_2038071_+	ncRNA_intronic
CAediting_1152133	chr17_2038076_+	ncRNA_intronic
CAediting_1152134	chr17_2038077_+	ncRNA_intronic
CAediting_1152135	chr17_2038081_+	ncRNA_intronic
CAediting_1152136	chr17_2038086_+	ncRNA_intronic
CAediting_1152137	chr17_2038100_+	ncRNA_intronic
CAediting_1152138	chr17_2038109_+	ncRNA_intronic
CAediting_1152139	chr17_2038111_+	ncRNA_intronic
CAediting_1152140	chr17_2038114_+	ncRNA_intronic
CAediting_1152141	chr17_2038123_+	ncRNA_intronic
CAediting_1152142	chr17_2038128_+	ncRNA_intronic
CAediting_1152143	chr17_2038133_+	ncRNA_intronic
CAediting_1152144	chr17_2038134_+	ncRNA_intronic
CAediting_1152145	chr17_2038150_+	ncRNA_intronic
CAediting_1152146	chr17_2038151_+	ncRNA_intronic
CAediting_1152147	chr17_2038157_+	ncRNA_intronic
CAediting_1152148	chr17_2038158_+	ncRNA_intronic
CAediting_1152149	chr17_2038159_+	ncRNA_intronic
CAediting_1152150	chr17_2038166_+	ncRNA_intronic
CAediting_1152151	chr17_2038167_+	ncRNA_intronic
CAediting_1152152	chr17_2038168_+	ncRNA_intronic
CAediting_1152153	chr17_2038169_+	ncRNA_intronic
CAediting_1152154	chr17_2038187_+	ncRNA_intronic
CAediting_1152155	chr17_2038189_+	ncRNA_intronic
CAediting_1152156	chr17_2038196_+	ncRNA_intronic
CAediting_1152157	chr17_2038204_+	ncRNA_intronic
CAediting_1152158	chr17_2038210_+	ncRNA_intronic
CAediting_1152159	chr17_2038218_+	ncRNA_intronic
CAediting_1152160	chr17_2038221_+	ncRNA_intronic
CAediting_1152161	chr17_2038227_+	ncRNA_intronic
CAediting_1152162	chr17_2038232_+	ncRNA_intronic
CAediting_1152163	chr17_2038234_+	ncRNA_intronic
CAediting_1152164	chr17_2038245_+	ncRNA_intronic
CAediting_1152165	chr17_2038253_+	ncRNA_intronic
CAediting_1152166	chr17_2038266_+	ncRNA_intronic
CAediting_1152167	chr17_2038270_+	ncRNA_intronic
CAediting_1152168	chr17_2038274_+	ncRNA_intronic
CAediting_1152169	chr17_2038290_+	ncRNA_intronic
CAediting_1152170	chr17_2038299_+	ncRNA_intronic
CAediting_1152171	chr17_2038301_+	ncRNA_intronic
CAediting_1152172	chr17_2038303_+	ncRNA_intronic
CAediting_1152173	chr17_2038306_+	ncRNA_intronic
CAediting_1152174	chr17_2038307_+	ncRNA_intronic
CAediting_1152175	chr17_2038309_+	ncRNA_intronic
CAediting_1152176	chr17_2038333_+	ncRNA_intronic
CAediting_1152177	chr17_2038558_+	ncRNA_intronic
CAediting_1152178	chr17_2039081_+	ncRNA_exonic
CAediting_1152179	chr17_2039083_+	ncRNA_exonic
CAediting_1152180	chr17_2039087_+	ncRNA_exonic
CAediting_1152181	chr17_2039126_+	ncRNA_exonic
CAediting_1152182	chr17_2039141_+	ncRNA_exonic
CAediting_1152183	chr17_2039162_+	ncRNA_exonic
CAediting_1152184	chr17_2039179_+	ncRNA_exonic
CAediting_1152185	chr17_2039188_+	ncRNA_exonic
CAediting_1152186	chr17_2039203_+	ncRNA_exonic
CAediting_1152187	chr17_2039217_+	ncRNA_exonic
CAediting_1152188	chr17_2039223_+	ncRNA_exonic
CAediting_1152189	chr17_2039227_+	ncRNA_exonic
CAediting_1152190	chr17_2039228_+	ncRNA_exonic
CAediting_1152191	chr17_2039243_+	ncRNA_exonic
CAediting_1152192	chr17_2039260_+	ncRNA_exonic
CAediting_1152193	chr17_2039268_+	ncRNA_exonic
CAediting_1152194	chr17_2039321_+	ncRNA_exonic
CAediting_1152195	chr17_2039322_+	ncRNA_exonic
CAediting_1152196	chr17_2039323_+	ncRNA_exonic
CAediting_1152197	chr17_2039335_+	ncRNA_exonic
CAediting_1152198	chr17_2039344_+	ncRNA_exonic
CAediting_1152199	chr17_2039397_+	ncRNA_exonic
CAediting_1152200	chr17_2039399_+	ncRNA_exonic
CAediting_1152201	chr17_2039442_+	ncRNA_exonic
CAediting_1152202	chr17_2039452_+	ncRNA_exonic
CAediting_1152203	chr17_2039458_+	ncRNA_exonic
CAediting_1152204	chr17_2039495_+	ncRNA_exonic
CAediting_1152205	chr17_2039504_+	ncRNA_exonic
CAediting_1152206	chr17_2039517_+	ncRNA_exonic
CAediting_1152207	chr17_2039519_+	ncRNA_exonic
CAediting_1152208	chr17_2039559_+	ncRNA_exonic
CAediting_1152209	chr17_2039584_+	ncRNA_exonic
CAediting_1152210	chr17_2039591_+	ncRNA_exonic
CAediting_1152211	chr17_2039638_+	ncRNA_exonic
CAediting_1152212	chr17_2039639_+	ncRNA_exonic
CAediting_1152213	chr17_2039651_+	ncRNA_exonic
CAediting_1152214	chr17_2039653_+	ncRNA_exonic
CAediting_1152215	chr17_2039660_+	ncRNA_exonic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1152122	chr17_2037836_+	SINE	MIR	MIRb
CAediting_1152123	chr17_2037905_+	SINE	MIR	MIRb
CAediting_1152124	chr17_2037999_+	SINE	MIR	MIRb
CAediting_1152125	chr17_2038036_+	SINE	Alu	AluJb
CAediting_1152126	chr17_2038038_+	SINE	Alu	AluJb
CAediting_1152127	chr17_2038046_+	SINE	Alu	AluJb
CAediting_1152128	chr17_2038054_+	SINE	Alu	AluJb
CAediting_1152129	chr17_2038055_+	SINE	Alu	AluJb
CAediting_1152130	chr17_2038060_+	SINE	Alu	AluJb
CAediting_1152131	chr17_2038061_+	SINE	Alu	AluJb
CAediting_1152132	chr17_2038071_+	SINE	Alu	AluJb
CAediting_1152133	chr17_2038076_+	SINE	Alu	AluJb
CAediting_1152134	chr17_2038077_+	SINE	Alu	AluJb
CAediting_1152135	chr17_2038081_+	SINE	Alu	AluJb
CAediting_1152136	chr17_2038086_+	SINE	Alu	AluJb
CAediting_1152137	chr17_2038100_+	SINE	Alu	AluJb
CAediting_1152138	chr17_2038109_+	SINE	Alu	AluJb
CAediting_1152139	chr17_2038111_+	SINE	Alu	AluJb
CAediting_1152140	chr17_2038114_+	SINE	Alu	AluJb
CAediting_1152141	chr17_2038123_+	SINE	Alu	AluJb
CAediting_1152142	chr17_2038128_+	SINE	Alu	AluJb
CAediting_1152143	chr17_2038133_+	SINE	Alu	AluJb
CAediting_1152144	chr17_2038134_+	SINE	Alu	AluJb
CAediting_1152145	chr17_2038150_+	SINE	Alu	AluJb
CAediting_1152146	chr17_2038151_+	SINE	Alu	AluJb
CAediting_1152147	chr17_2038157_+	SINE	Alu	AluJb
CAediting_1152148	chr17_2038158_+	SINE	Alu	AluJb
CAediting_1152149	chr17_2038159_+	SINE	Alu	AluJb
CAediting_1152150	chr17_2038166_+	SINE	Alu	AluJb
CAediting_1152151	chr17_2038167_+	SINE	Alu	AluJb
CAediting_1152152	chr17_2038168_+	SINE	Alu	AluJb
CAediting_1152153	chr17_2038169_+	SINE	Alu	AluJb
CAediting_1152154	chr17_2038187_+	SINE	Alu	AluJb
CAediting_1152155	chr17_2038189_+	SINE	Alu	AluJb
CAediting_1152156	chr17_2038196_+	SINE	Alu	AluJb
CAediting_1152157	chr17_2038204_+	SINE	Alu	AluJb
CAediting_1152158	chr17_2038210_+	SINE	Alu	AluJb
CAediting_1152159	chr17_2038218_+	SINE	Alu	AluJb
CAediting_1152160	chr17_2038221_+	SINE	Alu	AluJb
CAediting_1152161	chr17_2038227_+	SINE	Alu	AluJb
CAediting_1152162	chr17_2038232_+	SINE	Alu	AluJb
CAediting_1152163	chr17_2038234_+	SINE	Alu	AluJb
CAediting_1152164	chr17_2038245_+	SINE	Alu	AluJb
CAediting_1152165	chr17_2038253_+	SINE	Alu	AluJb
CAediting_1152166	chr17_2038266_+	SINE	Alu	AluJb
CAediting_1152167	chr17_2038270_+	SINE	Alu	AluJb
CAediting_1152168	chr17_2038274_+	SINE	Alu	AluJb
CAediting_1152169	chr17_2038290_+	SINE	Alu	AluJb
CAediting_1152170	chr17_2038299_+	SINE	Alu	AluJb
CAediting_1152171	chr17_2038301_+	SINE	Alu	AluJb
CAediting_1152172	chr17_2038303_+	SINE	Alu	AluJb
CAediting_1152173	chr17_2038306_+	SINE	Alu	AluJb
CAediting_1152174	chr17_2038307_+	SINE	Alu	AluJb
CAediting_1152175	chr17_2038309_+	SINE	Alu	AluJb
CAediting_1152176	chr17_2038333_+	SINE	Alu	AluJb
CAediting_1152177	chr17_2038558_+	DNA	hAT-Charlie	MER1B
CAediting_1152178	chr17_2039081_+	SINE	Alu	AluSc8
CAediting_1152179	chr17_2039083_+	SINE	Alu	AluSc8
CAediting_1152180	chr17_2039087_+	SINE	Alu	AluSc8
CAediting_1152181	chr17_2039126_+	SINE	Alu	AluSc8
CAediting_1152182	chr17_2039141_+	SINE	Alu	AluSc8
CAediting_1152183	chr17_2039162_+	SINE	Alu	AluSc8
CAediting_1152184	chr17_2039179_+	SINE	Alu	AluSc8
CAediting_1152185	chr17_2039188_+	SINE	Alu	AluSc8
CAediting_1152186	chr17_2039203_+	SINE	Alu	AluSc8
CAediting_1152187	chr17_2039217_+	SINE	Alu	AluSc8
CAediting_1152188	chr17_2039223_+	SINE	Alu	AluSc8
CAediting_1152189	chr17_2039227_+	SINE	Alu	AluSc8
CAediting_1152190	chr17_2039228_+	SINE	Alu	AluSc8
CAediting_1152191	chr17_2039243_+	SINE	Alu	AluSc8
CAediting_1152192	chr17_2039260_+	SINE	Alu	AluSc8
CAediting_1152193	chr17_2039268_+	SINE	Alu	AluSc8
CAediting_1152194	chr17_2039321_+	SINE	Alu	AluSc8
CAediting_1152195	chr17_2039322_+	SINE	Alu	AluSc8
CAediting_1152196	chr17_2039323_+	SINE	Alu	AluSc8
CAediting_1152197	chr17_2039335_+	SINE	Alu	AluSc8
CAediting_1152198	chr17_2039344_+	SINE	Alu	AluSc8
CAediting_1152199	chr17_2039397_+	SINE	Alu	AluY
CAediting_1152200	chr17_2039399_+	SINE	Alu	AluY
CAediting_1152201	chr17_2039442_+	SINE	Alu	AluY
CAediting_1152202	chr17_2039452_+	SINE	Alu	AluY
CAediting_1152203	chr17_2039458_+	SINE	Alu	AluY
CAediting_1152204	chr17_2039495_+	SINE	Alu	AluY
CAediting_1152205	chr17_2039504_+	SINE	Alu	AluY
CAediting_1152206	chr17_2039517_+	SINE	Alu	AluY
CAediting_1152207	chr17_2039519_+	SINE	Alu	AluY
CAediting_1152208	chr17_2039559_+	SINE	Alu	AluY
CAediting_1152209	chr17_2039584_+	SINE	Alu	AluY
CAediting_1152210	chr17_2039591_+	SINE	Alu	AluY
CAediting_1152211	chr17_2039638_+	SINE	Alu	AluY
CAediting_1152212	chr17_2039639_+	SINE	Alu	AluY
CAediting_1152213	chr17_2039651_+	SINE	Alu	AluY
CAediting_1152214	chr17_2039653_+	SINE	Alu	AluY
CAediting_1152215	chr17_2039660_+	SINE	Alu	AluY

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RNA A-to-I editing events in the alternative splicing sites for DPH1

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
IR	CAediting_1152123	chr17_2037905_+	2037891:2037913	3SS	0+6i	TTGTTACCTTCTGTAAAACAGGT	-10.61	TTGTTACCTTCTGTGAAACAGGT	-10.94
ES	CAediting_1152199	chr17_2039397_+	2039378:2039400	3SS	0+1i	TTTTTTTTTTTTCTTTTTGAGAC	-2.95	TTTTTTTTTTTTCTTTTTGGGAC	5.8
IR	CAediting_1152199	chr17_2039397_+	2039378:2039400	3SS	0+1i	TTTTTTTTTTTTCTTTTTGAGAC	-2.95	TTTTTTTTTTTTCTTTTTGGGAC	5.8
ES	CAediting_1152200	chr17_2039399_+	2039378:2039400	3SS	2+0i	TTTTTTTTTTTTCTTTTTGAGAC	-2.95	TTTTTTTTTTTTCTTTTTGAGGC	-3.19
IR	CAediting_1152200	chr17_2039399_+	2039378:2039400	3SS	2+0i	TTTTTTTTTTTTCTTTTTGAGAC	-2.95	TTTTTTTTTTTTCTTTTTGAGGC	-3.19

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000108963.16.DPH1.

Correlation between RNA A-to-I editing and PSI for ENSG00000108963.16.DPH1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for DPH1

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

LGG.CAediting_1152128.ENSG00000108963.DPH1.png
Soverview

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Protein coding region RNA A-to-I editings for DPH1

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for DPH1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for DPH1

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for DPH1

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LGG	CAediting_1152126	chr17_2038038_+	0.0466363048764621	0.255777414500207	.	.	.	.
OV	CAediting_1152128	chr17_2038054_+	0.0122266454675689	0.249710238507192	.	.	.	.
OV	CAediting_1152129	chr17_2038055_+	0.000970271262935858	0.299869950988313	.	.	.	.
STAD	CAediting_1152157	chr17_2038204_+	.	.	0.0160303657205526	0.207710563017237	0.033536921939271	0.183778287848577
ESCA	CAediting_1152157	chr17_2038204_+	0.00235505756122358	0.313342835179105	.	.	.	.
STAD	CAediting_1152164	chr17_2038245_+	.	.	.	.	0.0389677314388749	0.172257032628064
THCA	CAediting_1152174	chr17_2038307_+	0.0287770906838352	0.271359552325048	.	.	.	.
OV	CAediting_1152174	chr17_2038307_+	0.0120226337146545	0.277853646410993	.	.	.	.
GBM	CAediting_1152213	chr17_2039651_+	0.00035171163349738	0.46080267473831	.	.	.	.

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Relation with cancer stages for DPH1

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
ESCA	clinical_stage	CAediting_1152129	chr17_2038055_+	0.0163147800740172	-0.466411021894066
ESCA	clinical_stage	CAediting_1152213	chr17_2039651_+	0.0461603874828216	-0.521548044419076
KIRC	pathologic_stage	CAediting_1152164	chr17_2038245_+	0.00270318861837659	0.411454493738884
OV	clinical_stage	CAediting_1152128	chr17_2038054_+	0.0291300473344712	0.220496241765431
STAD	pathologic_stage	CAediting_1152159	chr17_2038218_+	0.00493925487643073	0.229906096614867

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Relation with survival for DPH1

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for DPH1

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for DPH1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
DPH1	C4310801	DEVELOPMENTAL DELAY WITH SHORT STATURE, DYSMORPHIC FEATURES, AND SPARSE HAIR	2	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene