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Editing gene: SDE2 (CAeditome ID:163859)

Gene summary for SDE2

Gene summary

Gene information	Gene symbol	SDE2
	Gene ID	163859
	Gene name	SDE2 telomere maintenance homolog
	Synonyms	C1orf55\|dJ671D7.1
	Cytomap	1q42.12
	Type of gene	protein-coding
	Description	replication stress response regulator SDE2UPF0667 protein C1orf55protein SDE2 homolog
	Modification date	20210518
	UniProtAcc	Q6IQ49
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
SDE2	GO:0003684	Replication stress response regulator SDE2	27906959
SDE2	GO:0016485	Replication stress response regulator SDE2	27906959
SDE2	GO:0016567	Replication stress response regulator SDE2	27906959
SDE2	GO:0031571	Replication stress response regulator SDE2	27906959
SDE2	GO:0034644	Replication stress response regulator SDE2	27906959
SDE2	GO:0005634	Replication stress response regulator SDE2	27906959
SDE2	GO:0005654	Replication stress response regulator SDE2	0000052
SDE2	GO:0005794	Replication stress response regulator SDE2	0000052
SDE2	GO:0005829	Replication stress response regulator SDE2	0000052
SDE2	GO:0005886	Replication stress response regulator SDE2	0000052
SDE2	GO:0016607	Replication stress response regulator SDE2	0000052

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RNA A-to-I events for SDE2

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000143751.9

RNA A-to-I editing events in Cancer.

CAediting_143380(225983561, -), CAediting_143381(225983579, -), CAediting_143382(225983625, -), CAediting_143383(225983627, -), CAediting_143384(225983639, -), CAediting_143385(225983640, -), CAediting_143386(225983648, -), CAediting_143387(225983661, -), CAediting_143388(225983672, -), CAediting_143389(225983676, -), CAediting_143390(225983677, -), CAediting_143391(225983699, -), CAediting_143392(225983704, -), CAediting_143393(225983968, -), CAediting_143394(225984002, -), CAediting_143395(225984064, -), CAediting_143396(225984081, -), CAediting_143397(225984107, -), CAediting_143398(225984116, -), CAediting_143399(225984125, -), CAediting_143400(225984135, -), CAediting_143401(225984164, -), CAediting_143402(225984165, -), CAediting_143403(225984195, -), CAediting_143404(225984203, -), CAediting_143405(225984239, -), CAediting_143406(225984240, -), CAediting_143407(225984552, -), CAediting_143408(225984554, -), CAediting_143409(225984576, -), CAediting_143410(225984621, -), CAediting_143411(225984629, -), CAediting_143412(225984639, -), CAediting_143413(225984646, -), CAediting_143414(225984678, -), CAediting_143415(225984698, -), CAediting_143416(225984723, -), CAediting_143417(225984772, -), CAediting_143418(225984806, -), CAediting_143419(225984826, -), CAediting_143420(225986111, -), CAediting_143421(225986112, -), CAediting_143422(225986118, -), CAediting_143423(225993867, -), CAediting_143424(225993880, -), CAediting_143425(225993907, -), CAediting_143426(225994188, -), CAediting_143427(225994205, -), CAediting_143428(225994900, -), CAediting_143429(225994958, -), CAediting_143430(225994994, -), CAediting_143431(225995000, -), CAediting_143432(225997502, -), CAediting_143433(225997527, -), CAediting_143434(225997578, -), CAediting_143435(225997590, -), CAediting_143436(225997594, -), CAediting_143437(225997633, -), CAediting_143438(225997635, -), CAediting_143439(225997673, -), CAediting_143440(225997691, -), CAediting_143441(225997896, -), CAediting_143442(225997926, -), CAediting_143443(225997964, -), CAediting_143444(225997970, -), CAediting_143445(225997992, -), CAediting_143446(225998019, -), CAediting_143447(225998044, -), CAediting_143448(225998045, -), CAediting_143449(225998090, -),

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RNA editing positional annotations for SDE2 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_143380	chr1_225983561_-	UTR3
CAediting_143381	chr1_225983579_-	UTR3
CAediting_143382	chr1_225983625_-	UTR3
CAediting_143383	chr1_225983627_-	UTR3
CAediting_143384	chr1_225983639_-	UTR3
CAediting_143385	chr1_225983640_-	UTR3
CAediting_143386	chr1_225983648_-	UTR3
CAediting_143387	chr1_225983661_-	UTR3
CAediting_143388	chr1_225983672_-	UTR3
CAediting_143389	chr1_225983676_-	UTR3
CAediting_143390	chr1_225983677_-	UTR3
CAediting_143391	chr1_225983699_-	UTR3
CAediting_143392	chr1_225983704_-	UTR3
CAediting_143393	chr1_225983968_-	UTR3
CAediting_143394	chr1_225984002_-	UTR3
CAediting_143395	chr1_225984064_-	UTR3
CAediting_143396	chr1_225984081_-	UTR3
CAediting_143397	chr1_225984107_-	UTR3
CAediting_143398	chr1_225984116_-	UTR3
CAediting_143399	chr1_225984125_-	UTR3
CAediting_143400	chr1_225984135_-	UTR3
CAediting_143401	chr1_225984164_-	UTR3
CAediting_143402	chr1_225984165_-	UTR3
CAediting_143403	chr1_225984195_-	UTR3
CAediting_143404	chr1_225984203_-	UTR3
CAediting_143405	chr1_225984239_-	UTR3
CAediting_143406	chr1_225984240_-	UTR3
CAediting_143407	chr1_225984552_-	UTR3
CAediting_143408	chr1_225984554_-	UTR3
CAediting_143409	chr1_225984576_-	UTR3
CAediting_143410	chr1_225984621_-	UTR3
CAediting_143411	chr1_225984629_-	UTR3
CAediting_143412	chr1_225984639_-	UTR3
CAediting_143413	chr1_225984646_-	UTR3
CAediting_143414	chr1_225984678_-	UTR3
CAediting_143415	chr1_225984698_-	UTR3
CAediting_143416	chr1_225984723_-	UTR3
CAediting_143417	chr1_225984772_-	UTR3
CAediting_143418	chr1_225984806_-	UTR3
CAediting_143419	chr1_225984826_-	UTR3
CAediting_143420	chr1_225986111_-	intronic
CAediting_143421	chr1_225986112_-	intronic
CAediting_143422	chr1_225986118_-	intronic
CAediting_143423	chr1_225993867_-	intronic
CAediting_143424	chr1_225993880_-	intronic
CAediting_143425	chr1_225993907_-	intronic
CAediting_143426	chr1_225994188_-	intronic
CAediting_143427	chr1_225994205_-	intronic
CAediting_143428	chr1_225994900_-	intronic
CAediting_143429	chr1_225994958_-	intronic
CAediting_143430	chr1_225994994_-	intronic
CAediting_143431	chr1_225995000_-	intronic
CAediting_143432	chr1_225997502_-	intronic
CAediting_143433	chr1_225997527_-	intronic
CAediting_143434	chr1_225997578_-	intronic
CAediting_143435	chr1_225997590_-	intronic
CAediting_143436	chr1_225997594_-	intronic
CAediting_143437	chr1_225997633_-	intronic
CAediting_143438	chr1_225997635_-	intronic
CAediting_143439	chr1_225997673_-	intronic
CAediting_143440	chr1_225997691_-	intronic
CAediting_143441	chr1_225997896_-	intronic
CAediting_143442	chr1_225997926_-	intronic
CAediting_143443	chr1_225997964_-	intronic
CAediting_143444	chr1_225997970_-	intronic
CAediting_143445	chr1_225997992_-	intronic
CAediting_143446	chr1_225998019_-	intronic
CAediting_143447	chr1_225998044_-	intronic
CAediting_143448	chr1_225998045_-	intronic
CAediting_143449	chr1_225998090_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_143380	chr1_225983561_-	SINE	Alu	AluSz6
CAediting_143381	chr1_225983579_-	SINE	Alu	AluSz6
CAediting_143382	chr1_225983625_-	SINE	Alu	AluSz6
CAediting_143383	chr1_225983627_-	SINE	Alu	AluSz6
CAediting_143384	chr1_225983639_-	SINE	Alu	AluSz6
CAediting_143385	chr1_225983640_-	SINE	Alu	AluSz6
CAediting_143386	chr1_225983648_-	SINE	Alu	AluSz6
CAediting_143387	chr1_225983661_-	SINE	Alu	AluSz6
CAediting_143388	chr1_225983672_-	SINE	Alu	AluSz6
CAediting_143389	chr1_225983676_-	SINE	Alu	AluSz6
CAediting_143390	chr1_225983677_-	SINE	Alu	AluSz6
CAediting_143391	chr1_225983699_-	SINE	Alu	AluSz6
CAediting_143392	chr1_225983704_-	LINE	L1	L1MEf
CAediting_143393	chr1_225983968_-	SINE	Alu	AluSq2
CAediting_143394	chr1_225984002_-	SINE	Alu	AluSq2
CAediting_143395	chr1_225984064_-	SINE	Alu	AluSq2
CAediting_143396	chr1_225984081_-	SINE	Alu	AluSq2
CAediting_143397	chr1_225984107_-	SINE	Alu	AluSq2
CAediting_143398	chr1_225984116_-	SINE	Alu	AluSq2
CAediting_143399	chr1_225984125_-	SINE	Alu	AluSq2
CAediting_143400	chr1_225984135_-	SINE	Alu	AluSq2
CAediting_143401	chr1_225984164_-	SINE	Alu	AluSq2
CAediting_143402	chr1_225984165_-	SINE	Alu	AluSq2
CAediting_143403	chr1_225984195_-	SINE	Alu	AluSq2
CAediting_143404	chr1_225984203_-	SINE	Alu	AluSq2
CAediting_143405	chr1_225984239_-	SINE	Alu	AluSq2
CAediting_143406	chr1_225984240_-	SINE	Alu	AluSq2
CAediting_143407	chr1_225984552_-	SINE	Alu	AluY
CAediting_143408	chr1_225984554_-	SINE	Alu	AluY
CAediting_143409	chr1_225984576_-	SINE	Alu	AluY
CAediting_143410	chr1_225984621_-	SINE	Alu	AluY
CAediting_143411	chr1_225984629_-	SINE	Alu	AluY
CAediting_143412	chr1_225984639_-	SINE	Alu	AluY
CAediting_143413	chr1_225984646_-	SINE	Alu	AluY
CAediting_143414	chr1_225984678_-	SINE	Alu	AluY
CAediting_143415	chr1_225984698_-	SINE	Alu	AluY
CAediting_143416	chr1_225984723_-	SINE	Alu	AluY
CAediting_143417	chr1_225984772_-	SINE	Alu	AluY
CAediting_143418	chr1_225984806_-	SINE	Alu	AluY
CAediting_143419	chr1_225984826_-	SINE	Alu	AluY
CAediting_143420	chr1_225986111_-	SINE	Alu	AluSz
CAediting_143421	chr1_225986112_-	SINE	Alu	AluSz
CAediting_143422	chr1_225986118_-	SINE	Alu	AluSz
CAediting_143423	chr1_225993867_-	SINE	Alu	AluJo
CAediting_143424	chr1_225993880_-	SINE	Alu	AluJo
CAediting_143425	chr1_225993907_-	SINE	Alu	AluJo
CAediting_143426	chr1_225994188_-	SINE	Alu	AluSx1
CAediting_143427	chr1_225994205_-	SINE	Alu	AluSx1
CAediting_143428	chr1_225994900_-	SINE	Alu	AluJb
CAediting_143429	chr1_225994958_-	SINE	Alu	AluJb
CAediting_143430	chr1_225994994_-	SINE	Alu	AluJb
CAediting_143431	chr1_225995000_-	SINE	Alu	AluJb
CAediting_143432	chr1_225997502_-	SINE	Alu	AluSx1
CAediting_143433	chr1_225997527_-	SINE	Alu	AluSx1
CAediting_143434	chr1_225997578_-	SINE	Alu	AluSx1
CAediting_143435	chr1_225997590_-	SINE	Alu	AluSx1
CAediting_143436	chr1_225997594_-	SINE	Alu	AluSx1
CAediting_143437	chr1_225997633_-	SINE	Alu	AluSx1
CAediting_143438	chr1_225997635_-	SINE	Alu	AluSx1
CAediting_143439	chr1_225997673_-	SINE	Alu	AluSx1
CAediting_143440	chr1_225997691_-	SINE	Alu	AluSx1
CAediting_143441	chr1_225997896_-	SINE	Alu	AluSq2
CAediting_143442	chr1_225997926_-	SINE	Alu	AluSq2
CAediting_143443	chr1_225997964_-	SINE	Alu	AluSq2
CAediting_143444	chr1_225997970_-	SINE	Alu	AluSq2
CAediting_143445	chr1_225997992_-	SINE	Alu	AluSq2
CAediting_143446	chr1_225998019_-	SINE	Alu	AluSq2
CAediting_143447	chr1_225998044_-	SINE	Alu	AluSq2
CAediting_143448	chr1_225998045_-	SINE	Alu	AluSq2
CAediting_143449	chr1_225998090_-	SINE	Alu	AluSq2

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RNA A-to-I editing events in the alternative splicing sites for SDE2

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000143751.9.SDE2.

Correlation between RNA A-to-I editing and PSI for ENSG00000143751.9.SDE2.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SDE2

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

BRCA.CAediting_143391.ENSG00000143751.SDE2.png
Soverview

LUAD.CAediting_143391.ENSG00000143751.SDE2.png
Soverview

LUSC.CAediting_143391.ENSG00000143751.SDE2.png
Soverview

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Protein coding region RNA A-to-I editings for SDE2

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for SDE2

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_143381	chr1_225983579_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6511a-3p	225983573	225983580	8mer-1a	225983573	225983592	157.00	-17.80
CAediting_143381	chr1_225983579_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6511a-3p	225983573	225983580	8mer-1a	225983573	225983592	157.00	-17.80
CAediting_143381	chr1_225983579_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6511a-3p	225983573	225983580	8mer-1a	225983573	225983592	157.00	-17.80
CAediting_143381	chr1_225983579_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6511a-3p	225983573	225983580	8mer-1a	225983573	225983592	157.00	-17.80
CAediting_143381	chr1_225983579_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6511b-3p	225983573	225983580	8mer-1a	225983573	225983593	150.00	-16.19
CAediting_143381	chr1_225983579_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6511b-3p	225983573	225983580	8mer-1a	225983573	225983593	150.00	-16.19
CAediting_143382	chr1_225983625_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4749-3p	225983622	225983628	7mer-m8	225983621	225983640	140.00	-16.67
CAediting_143382	chr1_225983625_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6769a-3p	225983621	225983627	7mer-m8	225983620	225983640	145.00	-17.77
CAediting_143383	chr1_225983627_-	ENSG00000143751.9	ENST00000272091	hsa-miR-150-5p	225983624	225983630	7mer-m8	225983623	225983642	141.00	-14.30
CAediting_143383	chr1_225983627_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6778-3p	225983622	225983628	7mer-m8	225983621	225983639	151.00	-18.03
CAediting_143384	chr1_225983639_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4494	225983635	225983640	6mer	225983634	225983655	146.00	-20.62
CAediting_143385	chr1_225983640_-	ENSG00000143751.9	ENST00000272091	hsa-miR-27a-3p	225983639	225983644	6mer	225983638	225983657	140.00	-12.43
CAediting_143385	chr1_225983640_-	ENSG00000143751.9	ENST00000272091	hsa-miR-27b-3p	225983639	225983644	6mer	225983638	225983657	140.00	-13.50
CAediting_143389	chr1_225983676_-	ENSG00000143751.9	ENST00000272091	hsa-miR-1269a	225983672	225983677	6mer	225983671	225983695	142.00	-23.44
CAediting_143389	chr1_225983676_-	ENSG00000143751.9	ENST00000272091	hsa-miR-1269b	225983672	225983677	6mer	225983671	225983695	146.00	-23.43
CAediting_143389	chr1_225983676_-	ENSG00000143751.9	ENST00000272091	hsa-miR-378a-3p	225983671	225983677	7mer-m8	225983670	225983690	150.00	-17.48
CAediting_143389	chr1_225983676_-	ENSG00000143751.9	ENST00000272091	hsa-miR-378b	225983671	225983677	7mer-m8	225983670	225983687	154.00	-21.45
CAediting_143389	chr1_225983676_-	ENSG00000143751.9	ENST00000272091	hsa-miR-378c	225983671	225983677	7mer-m8	225983670	225983693	150.00	-19.22
CAediting_143389	chr1_225983676_-	ENSG00000143751.9	ENST00000272091	hsa-miR-378d	225983671	225983677	7mer-m8	225983670	225983689	147.00	-16.04
CAediting_143389	chr1_225983676_-	ENSG00000143751.9	ENST00000272091	hsa-miR-378d	225983671	225983677	7mer-m8	225983670	225983689	147.00	-16.04
CAediting_143389	chr1_225983676_-	ENSG00000143751.9	ENST00000272091	hsa-miR-378e	225983671	225983677	7mer-m8	225983670	225983687	146.00	-18.16
CAediting_143389	chr1_225983676_-	ENSG00000143751.9	ENST00000272091	hsa-miR-378f	225983671	225983677	7mer-m8	225983670	225983689	147.00	-17.27
CAediting_143389	chr1_225983676_-	ENSG00000143751.9	ENST00000272091	hsa-miR-378h	225983671	225983677	7mer-m8	225983670	225983692	148.00	-17.65
CAediting_143389	chr1_225983676_-	ENSG00000143751.9	ENST00000272091	hsa-miR-378i	225983671	225983677	7mer-m8	225983670	225983692	152.00	-19.85
CAediting_143389	chr1_225983676_-	ENSG00000143751.9	ENST00000272091	hsa-miR-422a	225983671	225983677	7mer-m8	225983670	225983693	151.00	-19.11
CAediting_143390	chr1_225983677_-	ENSG00000143751.9	ENST00000272091	hsa-miR-513a-5p	225983676	225983682	7mer-m8	225983675	225983692	152.00	-17.32
CAediting_143390	chr1_225983677_-	ENSG00000143751.9	ENST00000272091	hsa-miR-513a-5p	225983676	225983682	7mer-m8	225983675	225983692	152.00	-17.32
CAediting_143391	chr1_225983699_-	ENSG00000143751.9	ENST00000272091	hsa-miR-941	225983696	225983702	7mer-m8	225983695	225983719	150.00	-25.81
CAediting_143391	chr1_225983699_-	ENSG00000143751.9	ENST00000272091	hsa-miR-941	225983696	225983702	7mer-m8	225983695	225983719	150.00	-25.81
CAediting_143391	chr1_225983699_-	ENSG00000143751.9	ENST00000272091	hsa-miR-941	225983696	225983702	7mer-m8	225983695	225983719	150.00	-25.81
CAediting_143391	chr1_225983699_-	ENSG00000143751.9	ENST00000272091	hsa-miR-941	225983696	225983702	7mer-m8	225983695	225983719	150.00	-25.81
CAediting_143391	chr1_225983699_-	ENSG00000143751.9	ENST00000272091	hsa-miR-941	225983696	225983702	7mer-m8	225983695	225983719	150.00	-25.81
CAediting_143392	chr1_225983704_-	ENSG00000143751.9	ENST00000272091	hsa-miR-186-3p	225983702	225983707	6mer	225983701	225983723	150.00	-17.34
CAediting_143392	chr1_225983704_-	ENSG00000143751.9	ENST00000272091	hsa-miR-3136-3p	225983699	225983706	8mer-1a	225983699	225983720	155.00	-17.85
CAediting_143392	chr1_225983704_-	ENSG00000143751.9	ENST00000272091	hsa-miR-7155-3p	225983699	225983706	8mer-1a	225983699	225983717	146.00	-16.84
CAediting_143410	chr1_225984621_-	ENSG00000143751.9	ENST00000272091	hsa-miR-3190-5p	225984616	225984622	7mer-m8	225984615	225984633	148.00	-20.60
CAediting_143410	chr1_225984621_-	ENSG00000143751.9	ENST00000272091	hsa-miR-548s	225984617	225984623	7mer-m8	225984616	225984638	149.00	-15.65
CAediting_143380	chr1_225983561_-	ENSG00000143751.9	ENST00000272091	hsa-miR-384	225983557	225983564	8mer-1a	225983557	225983577	156.00	-12.65
CAediting_143380	chr1_225983561_-	ENSG00000143751.9	ENST00000272091	hsa-miR-520g-5p	225983561	225983566	6mer	225983560	225983583	140.00	-16.38
CAediting_143394	chr1_225984002_-	ENSG00000143751.9	ENST00000272091	hsa-miR-3189-3p	225984001	225984007	7mer-m8	225984000	225984023	149.00	-20.72
CAediting_143394	chr1_225984002_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6813-3p	225984000	225984006	7mer-m8	225983999	225984019	140.00	-13.41
CAediting_143397	chr1_225984107_-	ENSG00000143751.9	ENST00000272091	hsa-miR-3622b-5p	225984105	225984111	7mer-m8	225984104	225984123	142.00	-20.58
CAediting_143397	chr1_225984107_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4645-5p	225984102	225984108	7mer-m8	225984101	225984119	142.00	-13.03
CAediting_143397	chr1_225984107_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4673	225984102	225984108	7mer-m8	225984101	225984126	153.00	-24.78
CAediting_143398	chr1_225984116_-	ENSG00000143751.9	ENST00000272091	hsa-miR-1203	225984115	225984121	7mer-m8	225984114	225984136	157.00	-24.83
CAediting_143398	chr1_225984116_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4743-5p	225984112	225984119	8mer-1a	225984112	225984134	140.00	-20.68
CAediting_143400	chr1_225984135_-	ENSG00000143751.9	ENST00000272091	hsa-miR-181a-2-3p	225984134	225984140	7mer-m8	225984133	225984152	143.00	-15.09
CAediting_143400	chr1_225984135_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4252	225984133	225984139	7mer-m8	225984132	225984150	151.00	-19.78
CAediting_143400	chr1_225984135_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4691-3p	225984131	225984137	7mer-m8	225984130	225984151	154.00	-25.80
CAediting_143401	chr1_225984164_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6078	225984160	225984167	8mer-1a	225984160	225984179	148.00	-20.42
CAediting_143403	chr1_225984195_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4537	225984190	225984197	8mer-1a	225984190	225984213	150.00	-21.44
CAediting_143412	chr1_225984639_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6849-3p	225984635	225984641	7mer-m8	225984634	225984655	140.00	-18.25
CAediting_143415	chr1_225984698_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4252	225984696	225984702	7mer-m8	225984695	225984713	143.00	-14.59
CAediting_143415	chr1_225984698_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4691-3p	225984694	225984700	7mer-m8	225984693	225984720	150.00	-26.82
CAediting_143416	chr1_225984723_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4304	225984723	225984729	7mer-m8	225984722	225984739	146.00	-19.00
CAediting_143406	chr1_225984240_-	ENSG00000143751.9	ENST00000272091	hsa-miR-605-5p	225984236	225984242	7mer-m8	225984235	225984257	150.00	-11.79
CAediting_143418	chr1_225984806_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4433b-5p	225984802	225984808	7mer-m8	225984801	225984821	140.00	-10.81

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_143389	chr1_225983676_-	ENSG00000143751.9	ENST00000272091	hsa-miR-10399-5p	225983675	225983681	7mer-m8	225983674	225983695	144	-10.26
CAediting_143390	chr1_225983677_-	ENSG00000143751.9	ENST00000272091	hsa-miR-10399-5p	225983675	225983681	7mer-m8	225983674	225983695	144	-10.26
CAediting_143414	chr1_225984678_-	ENSG00000143751.9	ENST00000272091	hsa-miR-1233-5p	225984677	225984683	7mer-m8	225984676	225984698	145	-22.42
CAediting_143414	chr1_225984678_-	ENSG00000143751.9	ENST00000272091	hsa-miR-1233-5p	225984677	225984683	7mer-m8	225984676	225984698	145	-22.42
CAediting_143393	chr1_225983968_-	ENSG00000143751.9	ENST00000272091	hsa-miR-1285-3p	225983967	225983973	7mer-m8	225983966	225983987	140	-16.54
CAediting_143393	chr1_225983968_-	ENSG00000143751.9	ENST00000272091	hsa-miR-1285-3p	225983967	225983973	7mer-m8	225983966	225983987	140	-16.54
CAediting_143411	chr1_225984629_-	ENSG00000143751.9	ENST00000272091	hsa-miR-216a-3p	225984624	225984630	7mer-m8	225984623	225984644	148	-20.2
CAediting_143410	chr1_225984621_-	ENSG00000143751.9	ENST00000272091	hsa-miR-3064-5p	225984616	225984621	6mer	225984615	225984635	140	-20.99
CAediting_143398	chr1_225984116_-	ENSG00000143751.9	ENST00000272091	hsa-miR-3135b	225984114	225984120	7mer-m8	225984113	225984134	150	-23.75
CAediting_143403	chr1_225984195_-	ENSG00000143751.9	ENST00000272091	hsa-miR-3160-3p	225984190	225984197	8mer-1a	225984190	225984211	150	-16.07
CAediting_143403	chr1_225984195_-	ENSG00000143751.9	ENST00000272091	hsa-miR-3160-3p	225984190	225984197	8mer-1a	225984190	225984211	150	-16.07
CAediting_143391	chr1_225983699_-	ENSG00000143751.9	ENST00000272091	hsa-miR-3176	225983698	225983704	7mer-m8	225983697	225983714	154	-20.09
CAediting_143417	chr1_225984772_-	ENSG00000143751.9	ENST00000272091	hsa-miR-324-3p	225984768	225984774	7mer-m8	225984767	225984789	148	-23.97
CAediting_143398	chr1_225984116_-	ENSG00000143751.9	ENST00000272091	hsa-miR-3652	225984112	225984119	8mer-1a	225984112	225984130	154	-19.67
CAediting_143396	chr1_225984081_-	ENSG00000143751.9	ENST00000272091	hsa-miR-3675-3p	225984076	225984082	7mer-m8	225984075	225984096	145	-12.58
CAediting_143411	chr1_225984629_-	ENSG00000143751.9	ENST00000272091	hsa-miR-3681-3p	225984624	225984630	7mer-m8	225984623	225984649	154	-23.87
CAediting_143418	chr1_225984806_-	ENSG00000143751.9	ENST00000272091	hsa-miR-371b-5p	225984804	225984811	8mer-1a	225984804	225984825	146	-7.79
CAediting_143383	chr1_225983627_-	ENSG00000143751.9	ENST00000272091	hsa-miR-372-5p	225983625	225983632	8mer-1a	225983625	225983648	148	-10.44
CAediting_143418	chr1_225984806_-	ENSG00000143751.9	ENST00000272091	hsa-miR-373-5p	225984804	225984811	8mer-1a	225984804	225984825	140	-8.35
CAediting_143388	chr1_225983672_-	ENSG00000143751.9	ENST00000272091	hsa-miR-378j	225983671	225983677	7mer-m8	225983670	225983687	146	-12.58
CAediting_143389	chr1_225983676_-	ENSG00000143751.9	ENST00000272091	hsa-miR-378j	225983671	225983677	7mer-m8	225983670	225983687	146	-12.58
CAediting_143387	chr1_225983661_-	ENSG00000143751.9	ENST00000272091	hsa-miR-380-3p	225983658	225983664	7mer-m8	225983657	225983678	147	-9.36
CAediting_143391	chr1_225983699_-	ENSG00000143751.9	ENST00000272091	hsa-miR-3922-3p	225983698	225983704	7mer-m8	225983697	225983720	150	-19.16
CAediting_143417	chr1_225984772_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4252	225984767	225984773	7mer-m8	225984766	225984786	149	-21.82
CAediting_143398	chr1_225984116_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4430	225984112	225984119	8mer-1a	225984112	225984129	146	-17.01
CAediting_143409	chr1_225984576_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4478	225984572	225984578	7mer-m8	225984571	225984587	150	-23.73
CAediting_143393	chr1_225983968_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4505	225983965	225983971	7mer-m8	225983964	225983982	151	-27.22
CAediting_143409	chr1_225984576_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4649-3p	225984575	225984581	7mer-m8	225984574	225984594	140	-14.13
CAediting_143417	chr1_225984772_-	ENSG00000143751.9	ENST00000272091	hsa-miR-4793-3p	225984771	225984777	7mer-m8	225984770	225984792	149	-21.81
CAediting_143409	chr1_225984576_-	ENSG00000143751.9	ENST00000272091	hsa-miR-485-5p	225984571	225984577	7mer-m8	225984570	225984592	149	-16.89
CAediting_143404	chr1_225984203_-	ENSG00000143751.9	ENST00000272091	hsa-miR-487b-3p	225984199	225984205	7mer-m8	225984198	225984219	142	-13.36
CAediting_143418	chr1_225984806_-	ENSG00000143751.9	ENST00000272091	hsa-miR-514b-5p	225984804	225984809	6mer	225984803	225984824	147	-11.14
CAediting_143393	chr1_225983968_-	ENSG00000143751.9	ENST00000272091	hsa-miR-5189-5p	225983967	225983973	7mer-m8	225983966	225983987	150	-20.57
CAediting_143416	chr1_225984723_-	ENSG00000143751.9	ENST00000272091	hsa-miR-5197-5p	225984721	225984727	7mer-m8	225984720	225984742	155	-13.37
CAediting_143400	chr1_225984135_-	ENSG00000143751.9	ENST00000272091	hsa-miR-5690	225984131	225984137	7mer-m8	225984130	225984150	145	-16.35
CAediting_143415	chr1_225984698_-	ENSG00000143751.9	ENST00000272091	hsa-miR-5690	225984694	225984700	7mer-m8	225984693	225984713	145	-16.35
CAediting_143393	chr1_225983968_-	ENSG00000143751.9	ENST00000272091	hsa-miR-5787	225983965	225983971	7mer-m8	225983964	225983982	146	-24.42
CAediting_143393	chr1_225983968_-	ENSG00000143751.9	ENST00000272091	hsa-miR-612	225983967	225983973	7mer-m8	225983966	225983989	153	-26.97
CAediting_143418	chr1_225984806_-	ENSG00000143751.9	ENST00000272091	hsa-miR-616-5p	225984804	225984811	8mer-1a	225984804	225984825	140	-6.13
CAediting_143410	chr1_225984621_-	ENSG00000143751.9	ENST00000272091	hsa-miR-664a-5p	225984616	225984622	7mer-m8	225984615	225984637	148	-14.11
CAediting_143391	chr1_225983699_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6765-3p	225983695	225983701	7mer-m8	225983694	225983714	146	-20.65
CAediting_143414	chr1_225984678_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6778-5p	225984677	225984683	7mer-m8	225984676	225984696	144	-17.36
CAediting_143382	chr1_225983625_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6819-3p	225983621	225983627	7mer-m8	225983620	225983640	140	-11.96
CAediting_143398	chr1_225984116_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6842-3p	225984112	225984118	7mer-m8	225984111	225984134	153	-26.81
CAediting_143393	chr1_225983968_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6860	225983967	225983973	7mer-m8	225983966	225983986	148	-20.42
CAediting_143382	chr1_225983625_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6877-3p	225983621	225983627	7mer-m8	225983620	225983640	140	-15.79
CAediting_143393	chr1_225983968_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6884-5p	225983963	225983969	7mer-m8	225983962	225983984	155	-21.4
CAediting_143409	chr1_225984576_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6884-5p	225984571	225984577	7mer-m8	225984570	225984592	155	-23.7
CAediting_143390	chr1_225983677_-	ENSG00000143751.9	ENST00000272091	hsa-miR-7151-3p	225983676	225983683	8mer-1a	225983676	225983692	146	-17.62
CAediting_143403	chr1_225984195_-	ENSG00000143751.9	ENST00000272091	hsa-miR-7160-5p	225984193	225984198	6mer	225984192	225984211	140	-18.78
CAediting_143409	chr1_225984576_-	ENSG00000143751.9	ENST00000272091	hsa-miR-7160-5p	225984574	225984580	7mer-m8	225984573	225984590	148	-23.73
CAediting_143395	chr1_225984064_-	ENSG00000143751.9	ENST00000272091	hsa-miR-7855-5p	225984064	225984069	6mer	225984063	225984082	148	-25.34
CAediting_143414	chr1_225984678_-	ENSG00000143751.9	ENST00000272091	hsa-miR-92a-2-5p	225984675	225984681	7mer-1a	225984675	225984696	140	-21.92

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1351755	chr19_40282625_-	ENSG00000143751.9	ENST00000272091	hsa-miR-641	225983564	225983570	7mer-m8	225983563	225983586	142	-16.72
CAediting_86358	chr1_109598906_+	ENSG00000143751.9	ENST00000272091	hsa-miR-197-5p	225984017	225984024	8mer-1a	225984017	225984045	146	-26.62
CAediting_86358	chr1_109598906_+	ENSG00000143751.9	ENST00000272091	hsa-miR-197-5p	225984582	225984588	7mer-m8	225984581	225984606	147	-29.38
CAediting_468389	chr6_31355314_-	ENSG00000143751.9	ENST00000272091	hsa-miR-6891-5p	225984138	225984145	8mer-1a	225984138	225984157	152	-25.5

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1160181	chr17_7017644_-	ENSG00000143751.9	ENST00000272091	hsa-miR-195-3p	225982800	225982806	7mer-m8	225982799	225982821	147	-7.86
CAediting_393	chr1_1167164_+	ENSG00000143751.9	ENST00000272091	hsa-miR-200b-3p	225985223	225985229	7mer-m8	225985222	225985243	141	-7.27
CAediting_77128	chr1_85133844_+	ENSG00000143751.9	ENST00000272091	hsa-miR-4423-3p	225983171	225983177	7mer-m8	225983170	225983190	154	-17.64
CAediting_688081	chr9_63819627_+	ENSG00000143751.9	ENST00000272091	hsa-miR-4477b	225984400	225984406	7mer-m8	225984399	225984419	147	-7.26
CAediting_1229413	chr17_67471544_+	ENSG00000143751.9	ENST00000272091	hsa-miR-548aa	225985101	225985107	7mer-m8	225985100	225985124	142	-6.46
CAediting_1229413	chr17_67471544_+	ENSG00000143751.9	ENST00000272091	hsa-miR-548aa	225984492	225984499	8mer-1a	225984492	225984517	150	-8.18
CAediting_1351755	chr19_40282625_-	ENSG00000143751.9	ENST00000272091	hsa-miR-641	225984936	225984942	7mer-m8	225984935	225984957	154	-13.47

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for SDE2

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000272091.7	protein_coding

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_143380	ENST00000272091.7	chr1_225983561_-	-1172.20	-1172.30	-1220.84
CAediting_143381	ENST00000272091.7	chr1_225983579_-	-1175.30	-1172.30	-1220.84
CAediting_143382	ENST00000272091.7	chr1_225983625_-	-1171.40	-1172.30	-1220.84
CAediting_143383	ENST00000272091.7	chr1_225983627_-	-1179.20	-1172.30	-1220.84
CAediting_143384	ENST00000272091.7	chr1_225983639_-	-1172.30	-1172.30	-1220.84
CAediting_143385	ENST00000272091.7	chr1_225983640_-	-1172.40	-1172.30	-1220.84
CAediting_143386	ENST00000272091.7	chr1_225983648_-	-1172.50	-1172.30	-1220.84
CAediting_143387	ENST00000272091.7	chr1_225983661_-	-1172.30	-1172.30	-1220.84
CAediting_143388	ENST00000272091.7	chr1_225983672_-	-1171.60	-1172.30	-1220.84
CAediting_143389	ENST00000272091.7	chr1_225983676_-	-1172.30	-1172.30	-1220.84
CAediting_143390	ENST00000272091.7	chr1_225983677_-	-1172.40	-1172.30	-1220.84
CAediting_143391	ENST00000272091.7	chr1_225983699_-	-1176.20	-1172.30	-1220.84
CAediting_143392	ENST00000272091.7	chr1_225983704_-	-1172.30	-1172.30	-1220.84
CAediting_143393	ENST00000272091.7	chr1_225983968_-	-1176.20	-1172.30	-1220.84
CAediting_143394	ENST00000272091.7	chr1_225984002_-	-1172.10	-1172.30	-1220.84
CAediting_143395	ENST00000272091.7	chr1_225984064_-	-1172.60	-1172.30	-1220.84
CAediting_143396	ENST00000272091.7	chr1_225984081_-	-1172.00	-1172.30	-1220.84
CAediting_143397	ENST00000272091.7	chr1_225984107_-	-1172.30	-1172.30	-1220.84
CAediting_143398	ENST00000272091.7	chr1_225984116_-	-1171.60	-1172.30	-1220.84
CAediting_143399	ENST00000272091.7	chr1_225984125_-	-1176.60	-1172.30	-1220.84
CAediting_143400	ENST00000272091.7	chr1_225984135_-	-1176.64	-1172.30	-1220.84
CAediting_143401	ENST00000272091.7	chr1_225984164_-	-1172.80	-1172.30	-1220.84
CAediting_143402	ENST00000272091.7	chr1_225984165_-	-1172.70	-1172.30	-1220.84
CAediting_143403	ENST00000272091.7	chr1_225984195_-	-1174.34	-1172.30	-1220.84
CAediting_143404	ENST00000272091.7	chr1_225984203_-	-1175.04	-1172.30	-1220.84
CAediting_143405	ENST00000272091.7	chr1_225984239_-	-1176.54	-1172.30	-1220.84
CAediting_143406	ENST00000272091.7	chr1_225984240_-	-1173.34	-1172.30	-1220.84
CAediting_143407	ENST00000272091.7	chr1_225984552_-	-1172.34	-1172.30	-1220.84
CAediting_143408	ENST00000272091.7	chr1_225984554_-	-1173.54	-1172.30	-1220.84
CAediting_143409	ENST00000272091.7	chr1_225984576_-	-1172.64	-1172.30	-1220.84
CAediting_143410	ENST00000272091.7	chr1_225984621_-	-1177.54	-1172.30	-1220.84
CAediting_143411	ENST00000272091.7	chr1_225984629_-	-1172.44	-1172.30	-1220.84
CAediting_143412	ENST00000272091.7	chr1_225984639_-	-1175.80	-1172.30	-1220.84
CAediting_143413	ENST00000272091.7	chr1_225984646_-	-1175.84	-1172.30	-1220.84
CAediting_143414	ENST00000272091.7	chr1_225984678_-	-1175.50	-1172.30	-1220.84
CAediting_143415	ENST00000272091.7	chr1_225984698_-	-1173.90	-1172.30	-1220.84
CAediting_143416	ENST00000272091.7	chr1_225984723_-	-1172.70	-1172.30	-1220.84
CAediting_143417	ENST00000272091.7	chr1_225984772_-	-1171.60	-1172.30	-1220.84
CAediting_143418	ENST00000272091.7	chr1_225984806_-	-1171.64	-1172.30	-1220.84
CAediting_143419	ENST00000272091.7	chr1_225984826_-	-1173.10	-1172.30	-1220.84

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Relation with ADAR for SDE2

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LGG	CAediting_143384	chr1_225983639_-	0.000381939384300771	0.29714702767994	.	.	.	.
BRCA	CAediting_143384	chr1_225983639_-	1.12150341233411e-08	0.251670121037538	.	.	.	.
LIHC	CAediting_143384	chr1_225983639_-	0.000114184366045953	0.269447889127402	.	.	.	.
LUAD	CAediting_143384	chr1_225983639_-	1.70268360413978e-05	0.277103587051348	.	.	.	.
LUSC	CAediting_143384	chr1_225983639_-	0.00774180349060445	0.171880653900952	.	.	.	.
PAAD	CAediting_143384	chr1_225983639_-	0.0420329866033229	0.259061528493273	.	.	.	.
TGCT	CAediting_143384	chr1_225983639_-	0.000538393456990529	0.382996912605067	.	.	.	.
LGG	CAediting_143389	chr1_225983676_-	0.0204723288645605	0.210507246540952	.	.	.	.
BRCA	CAediting_143389	chr1_225983676_-	1.13626834058518e-10	0.265546945124336	.	.	.	.
LIHC	CAediting_143389	chr1_225983676_-	0.028910845864493	0.148685511644324	.	.	.	.
CESC	CAediting_143389	chr1_225983676_-	0.0217010808590752	0.198934240224368	.	.	.	.
LUAD	CAediting_143389	chr1_225983676_-	9.26662887350587e-06	0.263807456799799	.	.	.	.
COAD	CAediting_143389	chr1_225983676_-	0.00177442692530071	0.26660178606443	.	.	.	.
LUSC	CAediting_143389	chr1_225983676_-	0.00380198395454473	0.172431979184168	.	.	0.00167704984312815	0.186958044424655
HNSC	CAediting_143389	chr1_225983676_-	.	.	0.00190398414033404	0.204566875717031	.	.
PAAD	CAediting_143389	chr1_225983676_-	0.0128822103323591	0.267195888171765	.	.	.	.
TGCT	CAediting_143389	chr1_225983676_-	0.00109992138834105	0.354091733671608	.	.	.	.
CESC	CAediting_143390	chr1_225983677_-	0.0320897048260952	0.247774447026641	.	.	.	.
HNSC	CAediting_143390	chr1_225983677_-	.	.	0.0268671437950703	0.189129958638549	.	.
UCEC	CAediting_143390	chr1_225983677_-	.	.	0.000168872610085595	0.431965956039462	0.00487505003793668	0.330521662138006
BLCA	CAediting_143391	chr1_225983699_-	2.98490677722022e-09	0.341110180868931	.	.	.	.
LGG	CAediting_143391	chr1_225983699_-	2.86380942774393e-09	0.283985353063384	.	.	.	.
BRCA	CAediting_143391	chr1_225983699_-	5.85263682844473e-47	0.432421176275522	.	.	.	.
LIHC	CAediting_143391	chr1_225983699_-	5.26401189188868e-07	0.274795361489181	.	.	.	.
CESC	CAediting_143391	chr1_225983699_-	0.000178401338217158	0.232164371277436	.	.	.	.
LUAD	CAediting_143391	chr1_225983699_-	7.29503698553014e-19	0.390518560337046	.	.	.	.
COAD	CAediting_143391	chr1_225983699_-	0.00012353753778313	0.215643469686621	.	.	.	.
LUSC	CAediting_143391	chr1_225983699_-	8.76624005481834e-16	0.359121702771655	.	.	.	.
GBM	CAediting_143391	chr1_225983699_-	0.00480701148227125	0.238718934509254	.	.	.	.
PRAD	CAediting_143391	chr1_225983699_-	4.34347092044698e-10	0.305887874933678	.	.	.	.
HNSC	CAediting_143391	chr1_225983699_-	5.23864891582871e-06	0.218656637203039	.	.	.	.
STAD	CAediting_143391	chr1_225983699_-	8.42664490682005e-05	0.232783103343911	.	.	.	.
THCA	CAediting_143391	chr1_225983699_-	1.54613231359489e-05	0.207484575108213	.	.	.	.
KIRC	CAediting_143391	chr1_225983699_-	6.10307763885773e-05	0.185587361556975	.	.	.	.
UCEC	CAediting_143391	chr1_225983699_-	1.65207966194599e-05	0.253426141730465	.	.	.	.
KIRP	CAediting_143391	chr1_225983699_-	0.0129407569017776	0.201849597728699	.	.	.	.
OV	CAediting_143391	chr1_225983699_-	0.00336032434987692	0.163224763606805	.	.	.	.
PAAD	CAediting_143391	chr1_225983699_-	8.62166404669979e-05	0.307220678054449	.	.	.	.
PCPG	CAediting_143391	chr1_225983699_-	1.15079472471694e-05	0.347523545443515	.	.	.	.
SKCM	CAediting_143391	chr1_225983699_-	0.000461254072927534	0.190310906745799	.	.	.	.
READ	CAediting_143391	chr1_225983699_-	0.0217032526563413	0.23287950932184	.	.	.	.
SARC	CAediting_143391	chr1_225983699_-	0.00080595226048232	0.235658150967921	.	.	.	.
TGCT	CAediting_143391	chr1_225983699_-	8.12820500242968e-11	0.525754142864755	.	.	.	.
THYM	CAediting_143391	chr1_225983699_-	2.52652342663111e-06	0.52881863039443	.	.	.	.
BLCA	CAediting_143410	chr1_225984621_-	.	.	0.000526633853178046	0.444825379773194	.	.
PCPG	CAediting_143410	chr1_225984621_-	0.0395632077153751	0.286384992384356	.	.	.	.
TGCT	CAediting_143410	chr1_225984621_-	0.0473080587498081	0.261590340398095	.	.	.	.

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Relation with cancer stages for SDE2

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BRCA	pathologic_stage	CAediting_143385	chr1_225983640_-	0.00129389075509016	-0.434350155596414
CESC	clinical_stage	CAediting_143391	chr1_225983699_-	0.0257638651938464	-0.140462475379445
CESC	clinical_stage	CAediting_143410	chr1_225984621_-	0.000258371483404144	-0.466069695359709
HNSC	clinical_stage	CAediting_143384	chr1_225983639_-	0.0411977498621756	0.14905548565976
HNSC	clinical_stage	CAediting_143410	chr1_225984621_-	0.037450847642609	0.210533271551343
HNSC	pathologic_stage	CAediting_143384	chr1_225983639_-	0.0323233353548107	0.161428482360204
HNSC	pathologic_stage	CAediting_143391	chr1_225983699_-	0.0206295781704133	0.119025799462443
KIRC	pathologic_stage	CAediting_143390	chr1_225983677_-	0.0199509185679036	0.256623591182077
KIRC	pathologic_stage	CAediting_143391	chr1_225983699_-	1.36079348590276e-08	0.261137519034752
KIRP	clinical_stage	CAediting_143391	chr1_225983699_-	0.00085184058163266	0.319225668331156
KIRP	pathologic_stage	CAediting_143391	chr1_225983699_-	0.000459638849520818	0.296358138926946
LUSC	pathologic_stage	CAediting_143391	chr1_225983699_-	0.0185107860334341	0.108954829890307
PAAD	pathologic_stage	CAediting_143391	chr1_225983699_-	0.0376089104088759	0.166102469182763
UCEC	clinical_stage	CAediting_143390	chr1_225983677_-	0.00708357669485937	0.316928938173797

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Relation with survival for SDE2

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
CESC	CAediting_143390	chr1_225983677_-	0.0438855189117275	0.0494457	1.37526e-05
LUAD	CAediting_143384	chr1_225983639_-	0.0432189435989746	0.0207975	54.9508
LUSC	CAediting_143390	chr1_225983677_-	0.0106050049733463	0.0362944	0.0114656
ESCA	CAediting_143384	chr1_225983639_-	0.00168893109955759	0.00216553	451278
ESCA	CAediting_143389	chr1_225983676_-	0.0270098239976913	0.00721717	623.69

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RelatedDrugs for SDE2

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for SDE2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene