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Editing gene: ZFPM1 (CAeditome ID:161882)

Gene summary for ZFPM1

Gene summary

Gene information	Gene symbol	ZFPM1
	Gene ID	161882
	Gene name	zinc finger protein, FOG family member 1
	Synonyms	FOG\|FOG1\|ZC2HC11A\|ZNF408\|ZNF89A
	Cytomap	16q24.2
	Type of gene	protein-coding
	Description	zinc finger protein ZFPM1FOG-1friend of GATA 1friend of GATA protein 1zinc finger protein 89Azinc finger protein, multitype 1
	Modification date	20210518
	UniProtAcc	Q8IX07
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
ZFPM1	GO:0010724	Zinc finger protein ZFPM1	15920471
ZFPM1	GO:0032713	Zinc finger protein ZFPM1	21646796
ZFPM1	GO:0032729	Zinc finger protein ZFPM1	21646796
ZFPM1	GO:0005667	Zinc finger protein ZFPM1	15920471
ZFPM1	GO:0017053	Zinc finger protein ZFPM1	15920471

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RNA A-to-I events for ZFPM1

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000179588.7

RNA A-to-I editing events in Cancer.

CAediting_1143207(88508072, +), CAediting_1143208(88508095, +), CAediting_1143209(88508254, +), CAediting_1143210(88508307, +), CAediting_1143211(88532855, +), CAediting_1143212(88536019, +), CAediting_1143213(88536142, +), CAediting_1143214(88536298, +),

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RNA editing positional annotations for ZFPM1 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1143207	chr16_88508072_+	intronic
CAediting_1143208	chr16_88508095_+	intronic
CAediting_1143209	chr16_88508254_+	intronic
CAediting_1143210	chr16_88508307_+	intronic
CAediting_1143211	chr16_88532855_+	exonic
CAediting_1143212	chr16_88536019_+	UTR3
CAediting_1143213	chr16_88536142_+	UTR3
CAediting_1143214	chr16_88536298_+	UTR3

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1143207	chr16_88508072_+	SINE	Alu	AluSz
CAediting_1143208	chr16_88508095_+	SINE	Alu	AluSz
CAediting_1143209	chr16_88508254_+	SINE	Alu	AluSz
CAediting_1143210	chr16_88508307_+	SINE	Alu	AluSz
CAediting_1143212	chr16_88536019_+	SINE	Alu	AluJb
CAediting_1143213	chr16_88536142_+	SINE	Alu	AluJb
CAediting_1143214	chr16_88536298_+	SINE	Alu	AluJr

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RNA A-to-I editing events in the alternative splicing sites for ZFPM1

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000179588.7.ZFPM1.

Correlation between RNA A-to-I editing and PSI for ENSG00000179588.7.ZFPM1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZFPM1

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for ZFPM1

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for ZFPM1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_846604	chr11_93733708_-	ENSG00000179588.7	ENST00000563351	hsa-miR-1304-3p	88516555	88516561	7mer-m8	88516541	88516562	140	-14.37
CAediting_524911	chr7_5495852_-	ENSG00000179588.7	ENST00000563351	hsa-miR-589-3p	88516337	88516343	7mer-m8	88516321	88516344	140	-18.91
CAediting_468389	chr6_31355314_-	ENSG00000179588.7	ENST00000563351	hsa-miR-6891-5p	88516501	88516507	7mer-m8	88516490	88516508	153	-25.85

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_688080	chr9_63819626_+	ENSG00000179588.7	ENST00000563351	hsa-miR-4477b	88516224	88516230	7mer-m8	88516211	88516231	155	-17.6
CAediting_580943	chr7_100356700_+	ENSG00000179588.7	ENST00000563351	hsa-miR-6840-3p	88516361	88516367	7mer-m8	88516345	88516368	151	-24.79

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ZFPM1

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for ZFPM1

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for ZFPM1

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for ZFPM1

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for ZFPM1

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for ZFPM1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene