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Editing gene: CYB5A (CAeditome ID:1528)

Gene summary for CYB5A

Gene summary

Gene information	Gene symbol	CYB5A
	Gene ID	1528
	Gene name	cytochrome b5 type A
	Synonyms	CYB5\|MCB5\|METAG
	Cytomap	18q22.3
	Type of gene	protein-coding
	Description	cytochrome b5cytochrome b5 type A (microsomal)epididymis secretory sperm binding proteintype 1 cyt-b5
	Modification date	20210518
	UniProtAcc	P00167
	Context	- 32581567(Association Between CYP17A1, CYB5A Polymorphisms and Efficacy of Abiraterone Acetate/Prednisone Treatment in Castration-Resistant Prostate Cancer Patients)

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
CYB5A	GO:0005829	Cytochrome b5	0000052
CYB5A	GO:0016020	Cytochrome b5	22375059
CYB5A	GO:0043231	Cytochrome b5	0000052

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RNA A-to-I events for CYB5A

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000166347.17

RNA A-to-I editing events in Cancer.

CAediting_1268255(74250911, -), CAediting_1268256(74250923, -), CAediting_1268257(74250924, -), CAediting_1268258(74250933, -), CAediting_1268259(74250946, -), CAediting_1268260(74250947, -), CAediting_1268261(74250951, -), CAediting_1268262(74250956, -), CAediting_1268263(74250963, -), CAediting_1268264(74250976, -), CAediting_1268265(74250980, -), CAediting_1268266(74250988, -), CAediting_1268267(74251000, -), CAediting_1268268(74251002, -), CAediting_1268269(74251005, -), CAediting_1268270(74251021, -), CAediting_1268271(74251040, -), CAediting_1268272(74251048, -), CAediting_1268273(74251051, -), CAediting_1268274(74251058, -), CAediting_1268275(74251087, -), CAediting_1268276(74251088, -), CAediting_1268277(74251094, -), CAediting_1268278(74251107, -), CAediting_1268279(74251113, -), CAediting_1268280(74251144, -), CAediting_1268281(74251156, -), CAediting_1268282(74251162, -), CAediting_1268283(74251164, -), CAediting_1268284(74252473, -), CAediting_1268285(74252732, -), CAediting_1268286(74252733, -), CAediting_1268287(74252737, -), CAediting_1268288(74252743, -), CAediting_1268289(74252751, -), CAediting_1268290(74252756, -), CAediting_1268291(74252769, -), CAediting_1268292(74252789, -), CAediting_1268293(74252793, -), CAediting_1268294(74252796, -), CAediting_1268295(74252800, -), CAediting_1268296(74252801, -), CAediting_1268297(74252841, -), CAediting_1268298(74252970, -), CAediting_1268299(74252975, -), CAediting_1268300(74252976, -), CAediting_1268301(74252982, -), CAediting_1268302(74253009, -), CAediting_1268303(74253934, -), CAediting_1268304(74253935, -), CAediting_1268305(74253936, -), CAediting_1268306(74253975, -), CAediting_1268307(74253976, -), CAediting_1268308(74254007, -), CAediting_1268309(74254010, -), CAediting_1268310(74254033, -), CAediting_1268311(74254042, -), CAediting_1268312(74254068, -), CAediting_1268313(74254072, -), CAediting_1268314(74254104, -), CAediting_1268315(74254133, -), CAediting_1268316(74254174, -), CAediting_1268317(74254550, -), CAediting_1268318(74254616, -), CAediting_1268319(74254631, -), CAediting_1268320(74254648, -), CAediting_1268321(74254658, -), CAediting_1268322(74254684, -), CAediting_1268323(74254692, -), CAediting_1268324(74254695, -), CAediting_1268325(74254698, -), CAediting_1268326(74254740, -), CAediting_1268327(74254744, -), CAediting_1268328(74254749, -), CAediting_1268329(74254792, -), CAediting_1268330(74254801, -), CAediting_1268331(74254815, -), CAediting_1268332(74257790, -), CAediting_1268333(74262884, -), CAediting_1268334(74262980, -), CAediting_1268335(74263793, -), CAediting_1268336(74263817, -), CAediting_1268337(74263981, -), CAediting_1268338(74263993, -), CAediting_1268339(74264019, -), CAediting_1268340(74264054, -), CAediting_1268341(74264062, -), CAediting_1268342(74264089, -), CAediting_1268343(74264115, -), CAediting_1268344(74264118, -), CAediting_1268345(74264128, -), CAediting_1268346(74264159, -), CAediting_1268347(74267305, -), CAediting_1268348(74267321, -), CAediting_1268349(74267330, -), CAediting_1268350(74267335, -), CAediting_1268351(74267438, -), CAediting_1268352(74289583, -), CAediting_1268353(74289596, -), CAediting_1268354(74289604, -), CAediting_1268355(74290305, -), CAediting_1268356(74290342, -), CAediting_1268357(74290343, -), CAediting_1268358(74290383, -), CAediting_1268359(74290391, -), CAediting_1268360(74290405, -), CAediting_1268361(74290409, -), CAediting_1268362(74290412, -), CAediting_1268363(74290418, -), CAediting_1268364(74290433, -), CAediting_1268365(74290461, -), CAediting_1268366(74290509, -), CAediting_1268367(74290524, -),

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RNA editing positional annotations for CYB5A using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1268255	chr18_74250911_-	UTR3
CAediting_1268256	chr18_74250923_-	UTR3
CAediting_1268257	chr18_74250924_-	UTR3
CAediting_1268258	chr18_74250933_-	UTR3
CAediting_1268259	chr18_74250946_-	UTR3
CAediting_1268260	chr18_74250947_-	UTR3
CAediting_1268261	chr18_74250951_-	UTR3
CAediting_1268262	chr18_74250956_-	UTR3
CAediting_1268263	chr18_74250963_-	UTR3
CAediting_1268264	chr18_74250976_-	UTR3
CAediting_1268265	chr18_74250980_-	UTR3
CAediting_1268266	chr18_74250988_-	UTR3
CAediting_1268267	chr18_74251000_-	UTR3
CAediting_1268268	chr18_74251002_-	UTR3
CAediting_1268269	chr18_74251005_-	UTR3
CAediting_1268270	chr18_74251021_-	UTR3
CAediting_1268271	chr18_74251040_-	UTR3
CAediting_1268272	chr18_74251048_-	UTR3
CAediting_1268273	chr18_74251051_-	UTR3
CAediting_1268274	chr18_74251058_-	UTR3
CAediting_1268275	chr18_74251087_-	UTR3
CAediting_1268276	chr18_74251088_-	UTR3
CAediting_1268277	chr18_74251094_-	UTR3
CAediting_1268278	chr18_74251107_-	UTR3
CAediting_1268279	chr18_74251113_-	UTR3
CAediting_1268280	chr18_74251144_-	UTR3
CAediting_1268281	chr18_74251156_-	UTR3
CAediting_1268282	chr18_74251162_-	UTR3
CAediting_1268283	chr18_74251164_-	UTR3
CAediting_1268284	chr18_74252473_-	UTR3
CAediting_1268285	chr18_74252732_-	UTR3
CAediting_1268286	chr18_74252733_-	UTR3
CAediting_1268287	chr18_74252737_-	UTR3
CAediting_1268288	chr18_74252743_-	UTR3
CAediting_1268289	chr18_74252751_-	UTR3
CAediting_1268290	chr18_74252756_-	UTR3
CAediting_1268291	chr18_74252769_-	UTR3
CAediting_1268292	chr18_74252789_-	UTR3
CAediting_1268293	chr18_74252793_-	UTR3
CAediting_1268294	chr18_74252796_-	UTR3
CAediting_1268295	chr18_74252800_-	UTR3
CAediting_1268296	chr18_74252801_-	UTR3
CAediting_1268297	chr18_74252841_-	UTR3
CAediting_1268298	chr18_74252970_-	UTR3
CAediting_1268299	chr18_74252975_-	UTR3
CAediting_1268300	chr18_74252976_-	UTR3
CAediting_1268301	chr18_74252982_-	UTR3
CAediting_1268302	chr18_74253009_-	UTR3
CAediting_1268303	chr18_74253934_-	ncRNA_intronic
CAediting_1268304	chr18_74253935_-	ncRNA_intronic
CAediting_1268305	chr18_74253936_-	ncRNA_intronic
CAediting_1268306	chr18_74253975_-	ncRNA_intronic
CAediting_1268307	chr18_74253976_-	ncRNA_intronic
CAediting_1268308	chr18_74254007_-	ncRNA_intronic
CAediting_1268309	chr18_74254010_-	ncRNA_intronic
CAediting_1268310	chr18_74254033_-	ncRNA_intronic
CAediting_1268311	chr18_74254042_-	ncRNA_intronic
CAediting_1268312	chr18_74254068_-	ncRNA_intronic
CAediting_1268313	chr18_74254072_-	ncRNA_intronic
CAediting_1268314	chr18_74254104_-	ncRNA_intronic
CAediting_1268315	chr18_74254133_-	ncRNA_intronic
CAediting_1268316	chr18_74254174_-	ncRNA_intronic
CAediting_1268317	chr18_74254550_-	ncRNA_intronic
CAediting_1268318	chr18_74254616_-	ncRNA_intronic
CAediting_1268319	chr18_74254631_-	ncRNA_intronic
CAediting_1268320	chr18_74254648_-	ncRNA_intronic
CAediting_1268321	chr18_74254658_-	ncRNA_intronic
CAediting_1268322	chr18_74254684_-	ncRNA_intronic
CAediting_1268323	chr18_74254692_-	ncRNA_intronic
CAediting_1268324	chr18_74254695_-	ncRNA_intronic
CAediting_1268325	chr18_74254698_-	ncRNA_intronic
CAediting_1268326	chr18_74254740_-	ncRNA_intronic
CAediting_1268327	chr18_74254744_-	ncRNA_intronic
CAediting_1268328	chr18_74254749_-	ncRNA_intronic
CAediting_1268329	chr18_74254792_-	ncRNA_intronic
CAediting_1268330	chr18_74254801_-	ncRNA_intronic
CAediting_1268331	chr18_74254815_-	ncRNA_intronic
CAediting_1268332	chr18_74257790_-	ncRNA_exonic
CAediting_1268333	chr18_74262884_-	ncRNA_intronic
CAediting_1268334	chr18_74262980_-	ncRNA_intronic
CAediting_1268335	chr18_74263793_-	ncRNA_intronic
CAediting_1268336	chr18_74263817_-	ncRNA_intronic
CAediting_1268337	chr18_74263981_-	ncRNA_intronic
CAediting_1268338	chr18_74263993_-	ncRNA_intronic
CAediting_1268339	chr18_74264019_-	ncRNA_intronic
CAediting_1268340	chr18_74264054_-	ncRNA_intronic
CAediting_1268341	chr18_74264062_-	ncRNA_intronic
CAediting_1268342	chr18_74264089_-	ncRNA_intronic
CAediting_1268343	chr18_74264115_-	ncRNA_intronic
CAediting_1268344	chr18_74264118_-	ncRNA_intronic
CAediting_1268345	chr18_74264128_-	ncRNA_intronic
CAediting_1268346	chr18_74264159_-	ncRNA_intronic
CAediting_1268347	chr18_74267305_-	ncRNA_intronic
CAediting_1268348	chr18_74267321_-	ncRNA_intronic
CAediting_1268349	chr18_74267330_-	ncRNA_intronic
CAediting_1268350	chr18_74267335_-	ncRNA_intronic
CAediting_1268351	chr18_74267438_-	ncRNA_intronic
CAediting_1268352	chr18_74289583_-	ncRNA_intronic
CAediting_1268353	chr18_74289596_-	ncRNA_intronic
CAediting_1268354	chr18_74289604_-	ncRNA_intronic
CAediting_1268355	chr18_74290305_-	ncRNA_intronic
CAediting_1268356	chr18_74290342_-	ncRNA_intronic
CAediting_1268357	chr18_74290343_-	ncRNA_intronic
CAediting_1268358	chr18_74290383_-	ncRNA_intronic
CAediting_1268359	chr18_74290391_-	ncRNA_intronic
CAediting_1268360	chr18_74290405_-	ncRNA_intronic
CAediting_1268361	chr18_74290409_-	ncRNA_intronic
CAediting_1268362	chr18_74290412_-	ncRNA_intronic
CAediting_1268363	chr18_74290418_-	ncRNA_intronic
CAediting_1268364	chr18_74290433_-	ncRNA_intronic
CAediting_1268365	chr18_74290461_-	ncRNA_intronic
CAediting_1268366	chr18_74290509_-	ncRNA_intronic
CAediting_1268367	chr18_74290524_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1268255	chr18_74250911_-	SINE	Alu	AluSx
CAediting_1268256	chr18_74250923_-	SINE	Alu	AluSx
CAediting_1268257	chr18_74250924_-	SINE	Alu	AluSx
CAediting_1268258	chr18_74250933_-	SINE	Alu	AluSx
CAediting_1268259	chr18_74250946_-	SINE	Alu	AluSx
CAediting_1268260	chr18_74250947_-	SINE	Alu	AluSx
CAediting_1268261	chr18_74250951_-	SINE	Alu	AluSx
CAediting_1268262	chr18_74250956_-	SINE	Alu	AluSx
CAediting_1268263	chr18_74250963_-	SINE	Alu	AluSx
CAediting_1268264	chr18_74250976_-	SINE	Alu	AluSx
CAediting_1268265	chr18_74250980_-	SINE	Alu	AluSx
CAediting_1268266	chr18_74250988_-	SINE	Alu	AluSx
CAediting_1268267	chr18_74251000_-	SINE	Alu	AluSx
CAediting_1268268	chr18_74251002_-	SINE	Alu	AluSx
CAediting_1268269	chr18_74251005_-	SINE	Alu	AluSx
CAediting_1268270	chr18_74251021_-	SINE	Alu	AluSx
CAediting_1268271	chr18_74251040_-	SINE	Alu	AluSx
CAediting_1268272	chr18_74251048_-	SINE	Alu	AluSx
CAediting_1268273	chr18_74251051_-	SINE	Alu	AluSx
CAediting_1268274	chr18_74251058_-	SINE	Alu	AluSx
CAediting_1268275	chr18_74251087_-	SINE	Alu	AluSx
CAediting_1268276	chr18_74251088_-	SINE	Alu	AluSx
CAediting_1268277	chr18_74251094_-	SINE	Alu	AluSx
CAediting_1268278	chr18_74251107_-	SINE	Alu	AluSx
CAediting_1268279	chr18_74251113_-	SINE	Alu	AluSx
CAediting_1268280	chr18_74251144_-	SINE	Alu	AluSx
CAediting_1268281	chr18_74251156_-	SINE	Alu	AluSx
CAediting_1268282	chr18_74251162_-	SINE	Alu	AluSx
CAediting_1268283	chr18_74251164_-	SINE	Alu	AluSx
CAediting_1268285	chr18_74252732_-	SINE	Alu	AluSq2
CAediting_1268286	chr18_74252733_-	SINE	Alu	AluSq2
CAediting_1268287	chr18_74252737_-	SINE	Alu	AluSq2
CAediting_1268288	chr18_74252743_-	SINE	Alu	AluSq2
CAediting_1268289	chr18_74252751_-	SINE	Alu	AluSq2
CAediting_1268290	chr18_74252756_-	SINE	Alu	AluSq2
CAediting_1268291	chr18_74252769_-	SINE	Alu	AluSq2
CAediting_1268292	chr18_74252789_-	SINE	Alu	AluSq2
CAediting_1268293	chr18_74252793_-	SINE	Alu	AluSq2
CAediting_1268294	chr18_74252796_-	SINE	Alu	AluSq2
CAediting_1268295	chr18_74252800_-	SINE	Alu	AluSq2
CAediting_1268296	chr18_74252801_-	SINE	Alu	AluSq2
CAediting_1268297	chr18_74252841_-	SINE	Alu	AluSq2
CAediting_1268298	chr18_74252970_-	SINE	Alu	AluSq2
CAediting_1268299	chr18_74252975_-	SINE	Alu	AluSq2
CAediting_1268300	chr18_74252976_-	SINE	Alu	AluSq2
CAediting_1268301	chr18_74252982_-	SINE	Alu	AluSq2
CAediting_1268303	chr18_74253934_-	SINE	Alu	AluSx1
CAediting_1268304	chr18_74253935_-	SINE	Alu	AluSx1
CAediting_1268305	chr18_74253936_-	SINE	Alu	AluSx1
CAediting_1268306	chr18_74253975_-	SINE	Alu	AluSx1
CAediting_1268307	chr18_74253976_-	SINE	Alu	AluSx1
CAediting_1268308	chr18_74254007_-	SINE	Alu	AluSx1
CAediting_1268309	chr18_74254010_-	SINE	Alu	AluSx1
CAediting_1268310	chr18_74254033_-	SINE	Alu	AluSx1
CAediting_1268311	chr18_74254042_-	SINE	Alu	AluSx1
CAediting_1268312	chr18_74254068_-	SINE	Alu	AluSx1
CAediting_1268313	chr18_74254072_-	SINE	Alu	AluSx1
CAediting_1268314	chr18_74254104_-	SINE	Alu	AluSx1
CAediting_1268315	chr18_74254133_-	SINE	Alu	AluSx1
CAediting_1268316	chr18_74254174_-	SINE	Alu	AluSx1
CAediting_1268317	chr18_74254550_-	SINE	Alu	AluY
CAediting_1268318	chr18_74254616_-	SINE	Alu	AluY
CAediting_1268319	chr18_74254631_-	SINE	Alu	AluY
CAediting_1268320	chr18_74254648_-	SINE	Alu	AluY
CAediting_1268321	chr18_74254658_-	SINE	Alu	AluY
CAediting_1268322	chr18_74254684_-	SINE	Alu	AluY
CAediting_1268323	chr18_74254692_-	SINE	Alu	AluY
CAediting_1268324	chr18_74254695_-	SINE	Alu	AluY
CAediting_1268325	chr18_74254698_-	SINE	Alu	AluY
CAediting_1268326	chr18_74254740_-	SINE	Alu	AluY
CAediting_1268327	chr18_74254744_-	SINE	Alu	AluY
CAediting_1268328	chr18_74254749_-	SINE	Alu	AluY
CAediting_1268329	chr18_74254792_-	SINE	Alu	AluY
CAediting_1268330	chr18_74254801_-	SINE	Alu	AluY
CAediting_1268331	chr18_74254815_-	SINE	Alu	AluY
CAediting_1268332	chr18_74257790_-	SINE	Alu	AluJb
CAediting_1268333	chr18_74262884_-	SINE	Alu	AluJb
CAediting_1268334	chr18_74262980_-	SINE	Alu	AluJb
CAediting_1268335	chr18_74263793_-	SINE	Alu	AluJb
CAediting_1268336	chr18_74263817_-	SINE	Alu	AluJb
CAediting_1268337	chr18_74263981_-	SINE	Alu	AluSx1
CAediting_1268338	chr18_74263993_-	SINE	Alu	AluSx1
CAediting_1268339	chr18_74264019_-	SINE	Alu	AluSx1
CAediting_1268340	chr18_74264054_-	SINE	Alu	AluSx1
CAediting_1268341	chr18_74264062_-	SINE	Alu	AluSx1
CAediting_1268342	chr18_74264089_-	SINE	Alu	AluSx1
CAediting_1268343	chr18_74264115_-	SINE	Alu	AluSx1
CAediting_1268344	chr18_74264118_-	SINE	Alu	AluSx1
CAediting_1268345	chr18_74264128_-	SINE	Alu	AluSx1
CAediting_1268346	chr18_74264159_-	SINE	Alu	AluSx1
CAediting_1268347	chr18_74267305_-	SINE	Alu	AluSx1
CAediting_1268348	chr18_74267321_-	SINE	Alu	AluSx1
CAediting_1268349	chr18_74267330_-	SINE	Alu	AluSx1
CAediting_1268350	chr18_74267335_-	SINE	Alu	AluSx1
CAediting_1268351	chr18_74267438_-	SINE	Alu	AluSx1
CAediting_1268352	chr18_74289583_-	SINE	Alu	AluSq2
CAediting_1268353	chr18_74289596_-	SINE	Alu	AluSq2
CAediting_1268354	chr18_74289604_-	SINE	Alu	AluSq2
CAediting_1268355	chr18_74290305_-	SINE	Alu	AluSz6
CAediting_1268356	chr18_74290342_-	SINE	Alu	AluSz6
CAediting_1268357	chr18_74290343_-	SINE	Alu	AluSz6
CAediting_1268358	chr18_74290383_-	SINE	Alu	AluSz6
CAediting_1268359	chr18_74290391_-	SINE	Alu	AluSz6
CAediting_1268360	chr18_74290405_-	SINE	Alu	AluSz6
CAediting_1268361	chr18_74290409_-	SINE	Alu	AluSz6
CAediting_1268362	chr18_74290412_-	SINE	Alu	AluSz6
CAediting_1268363	chr18_74290418_-	SINE	Alu	AluSz6
CAediting_1268364	chr18_74290433_-	SINE	Alu	AluSz6
CAediting_1268365	chr18_74290461_-	SINE	Alu	AluSz6
CAediting_1268366	chr18_74290509_-	SINE	Alu	AluSz6
CAediting_1268367	chr18_74290524_-	SINE	Alu	AluSz6

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RNA A-to-I editing events in the alternative splicing sites for CYB5A

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000166347.17.CYB5A.

Correlation between RNA A-to-I editing and PSI for ENSG00000166347.17.CYB5A.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CYB5A

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

KIRC.CAediting_1268296.ENSG00000166347.CYB5A.png
Soverview

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Protein coding region RNA A-to-I editings for CYB5A

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for CYB5A

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1229415	chr17_67471547_+	ENSG00000166347.17	ENST00000299438	hsa-miR-548aa	74253303	74253309	7mer-m8	74253302	74253326	167	-10.15
CAediting_1229415	chr17_67471547_+	ENSG00000166347.17	ENST00000494131	hsa-miR-548aa	74253303	74253309	7mer-m8	74253302	74253326	167	-10.15
CAediting_468389	chr6_31355314_-	ENSG00000166347.17	ENST00000494131	hsa-miR-6891-5p	74253573	74253580	8mer-1a	74253573	74253591	142	-18.26

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CYB5A

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for CYB5A

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
KIRC	CAediting_1268269	chr18_74251005_-	0.0018823420338696	0.241692859919888	.	.	.	.
KIRC	CAediting_1268272	chr18_74251048_-	0.000457894674721226	0.441938544917576	.	.	.	.
KIRC	CAediting_1268303	chr18_74253934_-	0.0293993743273343	0.268294092239735	.	.	.	.

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Relation with cancer stages for CYB5A

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for CYB5A

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for CYB5A

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
CYB5A	P00167	DB11136	Chromium	Cytochrome b5	SmallMoleculeDrug	approved
CYB5A	P00167	DB14527	Chromic nitrate	Cytochrome b5	SmallMoleculeDrug	approved
CYB5A	P00167	DB14528	Chromium gluconate	Cytochrome b5	SmallMoleculeDrug	approved
CYB5A	P00167	DB14530	Chromous sulfate	Cytochrome b5	SmallMoleculeDrug	approved
CYB5A	P00167	DB14529	Chromium nicotinate	Cytochrome b5	SmallMoleculeDrug	approved\|experimental

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RelatedDiseases for CYB5A

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
CYB5A	C4285231	METHEMOGLOBINEMIA AND AMBIGUOUS GENITALIA	3	GENOMICS_ENGLAND;UNIPROT
CYB5A	C0014175	Endometriosis	1	CTD_human
CYB5A	C0028754	Obesity	1	CTD_human
CYB5A	C0035222	Respiratory Distress Syndrome, Adult	1	CTD_human
CYB5A	C0268285	Adrenal hyperplasia, congenital, type 5	1	ORPHANET
CYB5A	C0269102	Endometrioma	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene