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Editing gene: CCDC80 (CAeditome ID:151887)

Gene summary for CCDC80

Gene summary

Gene information	Gene symbol	CCDC80
	Gene ID	151887
	Gene name	coiled-coil domain containing 80
	Synonyms	CL2\|DRO1\|LINC01279\|SSG1\|URB\|okuribin
	Cytomap	3q13.2
	Type of gene	protein-coding
	Description	coiled-coil domain-containing protein 80TCONS_00006930down-regulated by oncogenes protein 1long intergenic non-protein coding RNA 1279nuclear envelope protein okuribinsteroid sensitive gene 1up-regulated in BRS-3 deficient mouse homolog
	Modification date	20210518
	UniProtAcc	Q76M96
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for CCDC80

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000091986.14

RNA A-to-I editing events in Cancer.

CAediting_299948(112596962, -), CAediting_299949(112596984, -), CAediting_299950(112600526, -), CAediting_299951(112600527, -), CAediting_299952(112600554, -), CAediting_299953(112600557, -), CAediting_299954(112600559, -), CAediting_299955(112600578, -), CAediting_299956(112600585, -), CAediting_299957(112600591, -), CAediting_299958(112600594, -), CAediting_299959(112600599, -), CAediting_299960(112600607, -), CAediting_299961(112600610, -), CAediting_299962(112600612, -), CAediting_299963(112600616, -), CAediting_299964(112600623, -), CAediting_299965(112600626, -), CAediting_299966(112600630, -), CAediting_299967(112600634, -), CAediting_299968(112600657, -), CAediting_299969(112600669, -), CAediting_299970(112600670, -), CAediting_299971(112600672, -), CAediting_299972(112600673, -), CAediting_299973(112600676, -), CAediting_299974(112600678, -), CAediting_299975(112600679, -), CAediting_299976(112600680, -), CAediting_299977(112600681, -), CAediting_299978(112600697, -), CAediting_299979(112600699, -), CAediting_299980(112600700, -), CAediting_299981(112600705, -), CAediting_299982(112600707, -), CAediting_299983(112600717, -), CAediting_299984(112600720, -), CAediting_299985(112600755, -), CAediting_299986(112600776, -), CAediting_299987(112600777, -), CAediting_299988(112600783, -), CAediting_299989(112600785, -), CAediting_299990(112600793, -), CAediting_299991(112600803, -), CAediting_299992(112601574, -), CAediting_299993(112601575, -), CAediting_299994(112601583, -), CAediting_299995(112601596, -), CAediting_299996(112601597, -), CAediting_299997(112601599, -), CAediting_299998(112601600, -), CAediting_299999(112601601, -), CAediting_300000(112601611, -), CAediting_300001(112601615, -), CAediting_300002(112601616, -), CAediting_300003(112601632, -), CAediting_300004(112601638, -), CAediting_300005(112601641, -), CAediting_300006(112601657, -), CAediting_300007(112601675, -), CAediting_300008(112603264, -), CAediting_300009(112603270, -), CAediting_300010(112603282, -), CAediting_300011(112603283, -), CAediting_300012(112603284, -), CAediting_300013(112603303, -), CAediting_300014(112603327, -), CAediting_300015(112603335, -), CAediting_300016(112603349, -), CAediting_300017(112603352, -), CAediting_300018(112603391, -), CAediting_300019(112603393, -), CAediting_300020(112603397, -), CAediting_300021(112603406, -), CAediting_300022(112603432, -), CAediting_300023(112603433, -), CAediting_300024(112603452, -), CAediting_300025(112603601, -), CAediting_300026(112606628, -), CAediting_300027(112606697, -), CAediting_300028(112606698, -), CAediting_300029(112621241, -), CAediting_300030(112638419, -),

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RNA editing positional annotations for CCDC80 using Annovar

Protein coding RNA editing(s).

CAeditome ID	Position	Variant type	ENST	NTchange	AAchange	SIFT_score	Polyphen2_HVAR_score	PROVEAN_pred
CAediting_300030	chr3_112638419_-	nonsynonymous SNV	ENST00000206423.6	c.A1487G	p.K496R	D	D	N
CAediting_300030	chr3_112638419_-	nonsynonymous SNV	ENST00000439685.5	c.A1487G	p.K496R	D	D	N

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_299948	chr3_112596962_-	UTR3
CAediting_299949	chr3_112596984_-	UTR3
CAediting_299950	chr3_112600526_-	UTR3
CAediting_299951	chr3_112600527_-	UTR3
CAediting_299952	chr3_112600554_-	UTR3
CAediting_299953	chr3_112600557_-	UTR3
CAediting_299954	chr3_112600559_-	UTR3
CAediting_299955	chr3_112600578_-	UTR3
CAediting_299956	chr3_112600585_-	UTR3
CAediting_299957	chr3_112600591_-	UTR3
CAediting_299958	chr3_112600594_-	UTR3
CAediting_299959	chr3_112600599_-	UTR3
CAediting_299960	chr3_112600607_-	UTR3
CAediting_299961	chr3_112600610_-	UTR3
CAediting_299962	chr3_112600612_-	UTR3
CAediting_299963	chr3_112600616_-	UTR3
CAediting_299964	chr3_112600623_-	UTR3
CAediting_299965	chr3_112600626_-	UTR3
CAediting_299966	chr3_112600630_-	UTR3
CAediting_299967	chr3_112600634_-	UTR3
CAediting_299968	chr3_112600657_-	UTR3
CAediting_299969	chr3_112600669_-	UTR3
CAediting_299970	chr3_112600670_-	UTR3
CAediting_299971	chr3_112600672_-	UTR3
CAediting_299972	chr3_112600673_-	UTR3
CAediting_299973	chr3_112600676_-	UTR3
CAediting_299974	chr3_112600678_-	UTR3
CAediting_299975	chr3_112600679_-	UTR3
CAediting_299976	chr3_112600680_-	UTR3
CAediting_299977	chr3_112600681_-	UTR3
CAediting_299978	chr3_112600697_-	UTR3
CAediting_299979	chr3_112600699_-	UTR3
CAediting_299980	chr3_112600700_-	UTR3
CAediting_299981	chr3_112600705_-	UTR3
CAediting_299982	chr3_112600707_-	UTR3
CAediting_299983	chr3_112600717_-	UTR3
CAediting_299984	chr3_112600720_-	UTR3
CAediting_299985	chr3_112600755_-	UTR3
CAediting_299986	chr3_112600776_-	UTR3
CAediting_299987	chr3_112600777_-	UTR3
CAediting_299988	chr3_112600783_-	UTR3
CAediting_299989	chr3_112600785_-	UTR3
CAediting_299990	chr3_112600793_-	UTR3
CAediting_299991	chr3_112600803_-	UTR3
CAediting_299992	chr3_112601574_-	UTR3
CAediting_299993	chr3_112601575_-	UTR3
CAediting_299994	chr3_112601583_-	UTR3
CAediting_299995	chr3_112601596_-	UTR3
CAediting_299996	chr3_112601597_-	UTR3
CAediting_299997	chr3_112601599_-	UTR3
CAediting_299998	chr3_112601600_-	UTR3
CAediting_299999	chr3_112601601_-	UTR3
CAediting_300000	chr3_112601611_-	UTR3
CAediting_300001	chr3_112601615_-	UTR3
CAediting_300002	chr3_112601616_-	UTR3
CAediting_300003	chr3_112601632_-	UTR3
CAediting_300004	chr3_112601638_-	UTR3
CAediting_300005	chr3_112601641_-	UTR3
CAediting_300006	chr3_112601657_-	UTR3
CAediting_300007	chr3_112601675_-	UTR3
CAediting_300008	chr3_112603264_-	UTR3
CAediting_300009	chr3_112603270_-	UTR3
CAediting_300010	chr3_112603282_-	UTR3
CAediting_300011	chr3_112603283_-	UTR3
CAediting_300012	chr3_112603284_-	UTR3
CAediting_300013	chr3_112603303_-	UTR3
CAediting_300014	chr3_112603327_-	UTR3
CAediting_300015	chr3_112603335_-	UTR3
CAediting_300016	chr3_112603349_-	UTR3
CAediting_300017	chr3_112603352_-	UTR3
CAediting_300018	chr3_112603391_-	UTR3
CAediting_300019	chr3_112603393_-	UTR3
CAediting_300020	chr3_112603397_-	UTR3
CAediting_300021	chr3_112603406_-	UTR3
CAediting_300022	chr3_112603432_-	UTR3
CAediting_300023	chr3_112603433_-	UTR3
CAediting_300024	chr3_112603452_-	UTR3
CAediting_300025	chr3_112603601_-	UTR3
CAediting_300026	chr3_112606628_-	intronic
CAediting_300027	chr3_112606697_-	intronic
CAediting_300028	chr3_112606698_-	intronic
CAediting_300029	chr3_112621241_-	intronic
CAediting_300030	chr3_112638419_-	exonic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_299948	chr3_112596962_-	LTR	ERVL	LTR108a_Mam
CAediting_299949	chr3_112596984_-	LTR	ERVL	LTR108a_Mam
CAediting_299950	chr3_112600526_-	SINE	Alu	AluJb
CAediting_299951	chr3_112600527_-	SINE	Alu	AluJb
CAediting_299952	chr3_112600554_-	SINE	Alu	AluJb
CAediting_299953	chr3_112600557_-	SINE	Alu	AluJb
CAediting_299954	chr3_112600559_-	SINE	Alu	AluJb
CAediting_299955	chr3_112600578_-	SINE	Alu	AluJb
CAediting_299956	chr3_112600585_-	SINE	Alu	AluJb
CAediting_299957	chr3_112600591_-	SINE	Alu	AluJb
CAediting_299958	chr3_112600594_-	SINE	Alu	AluJb
CAediting_299959	chr3_112600599_-	SINE	Alu	AluJb
CAediting_299960	chr3_112600607_-	SINE	Alu	AluJb
CAediting_299961	chr3_112600610_-	SINE	Alu	AluJb
CAediting_299962	chr3_112600612_-	SINE	Alu	AluJb
CAediting_299963	chr3_112600616_-	SINE	Alu	AluJb
CAediting_299964	chr3_112600623_-	SINE	Alu	AluJb
CAediting_299965	chr3_112600626_-	SINE	Alu	AluJb
CAediting_299966	chr3_112600630_-	SINE	Alu	AluJb
CAediting_299967	chr3_112600634_-	SINE	Alu	AluJb
CAediting_299968	chr3_112600657_-	SINE	Alu	AluJb
CAediting_299969	chr3_112600669_-	SINE	Alu	AluJb
CAediting_299970	chr3_112600670_-	SINE	Alu	AluJb
CAediting_299971	chr3_112600672_-	SINE	Alu	AluJb
CAediting_299972	chr3_112600673_-	SINE	Alu	AluJb
CAediting_299973	chr3_112600676_-	SINE	Alu	AluJb
CAediting_299974	chr3_112600678_-	SINE	Alu	AluJb
CAediting_299975	chr3_112600679_-	SINE	Alu	AluJb
CAediting_299976	chr3_112600680_-	SINE	Alu	AluJb
CAediting_299977	chr3_112600681_-	SINE	Alu	AluJb
CAediting_299978	chr3_112600697_-	SINE	Alu	AluJb
CAediting_299979	chr3_112600699_-	SINE	Alu	AluJb
CAediting_299980	chr3_112600700_-	SINE	Alu	AluJb
CAediting_299981	chr3_112600705_-	SINE	Alu	AluJb
CAediting_299982	chr3_112600707_-	SINE	Alu	AluJb
CAediting_299983	chr3_112600717_-	SINE	Alu	AluJb
CAediting_299984	chr3_112600720_-	SINE	Alu	AluJb
CAediting_299985	chr3_112600755_-	SINE	Alu	AluJb
CAediting_299986	chr3_112600776_-	SINE	Alu	AluJb
CAediting_299987	chr3_112600777_-	SINE	Alu	AluJb
CAediting_299988	chr3_112600783_-	SINE	Alu	AluJb
CAediting_299989	chr3_112600785_-	SINE	Alu	AluJb
CAediting_299990	chr3_112600793_-	SINE	Alu	AluJb
CAediting_299991	chr3_112600803_-	SINE	Alu	AluJb
CAediting_299992	chr3_112601574_-	SINE	Alu	AluJb
CAediting_299993	chr3_112601575_-	SINE	Alu	AluJb
CAediting_299994	chr3_112601583_-	SINE	Alu	AluJb
CAediting_299995	chr3_112601596_-	SINE	Alu	AluJb
CAediting_299996	chr3_112601597_-	SINE	Alu	AluJb
CAediting_299997	chr3_112601599_-	SINE	Alu	AluJb
CAediting_299998	chr3_112601600_-	SINE	Alu	AluJb
CAediting_299999	chr3_112601601_-	SINE	Alu	AluJb
CAediting_300000	chr3_112601611_-	SINE	Alu	AluJb
CAediting_300001	chr3_112601615_-	SINE	Alu	AluJb
CAediting_300002	chr3_112601616_-	SINE	Alu	AluJb
CAediting_300003	chr3_112601632_-	SINE	Alu	AluJb
CAediting_300004	chr3_112601638_-	SINE	Alu	AluJb
CAediting_300005	chr3_112601641_-	SINE	Alu	AluJb
CAediting_300006	chr3_112601657_-	SINE	Alu	AluJb
CAediting_300007	chr3_112601675_-	SINE	Alu	AluJb
CAediting_300008	chr3_112603264_-	SINE	Alu	AluSx1
CAediting_300009	chr3_112603270_-	SINE	Alu	AluSx1
CAediting_300010	chr3_112603282_-	SINE	Alu	AluSx1
CAediting_300011	chr3_112603283_-	SINE	Alu	AluSx1
CAediting_300012	chr3_112603284_-	SINE	Alu	AluSx1
CAediting_300013	chr3_112603303_-	SINE	Alu	AluSx1
CAediting_300014	chr3_112603327_-	SINE	Alu	AluSx1
CAediting_300015	chr3_112603335_-	SINE	Alu	AluSx1
CAediting_300016	chr3_112603349_-	SINE	Alu	AluSx1
CAediting_300017	chr3_112603352_-	SINE	Alu	AluSx1
CAediting_300018	chr3_112603391_-	SINE	Alu	AluSx1
CAediting_300019	chr3_112603393_-	SINE	Alu	AluSx1
CAediting_300020	chr3_112603397_-	SINE	Alu	AluSx1
CAediting_300021	chr3_112603406_-	SINE	Alu	AluSx1
CAediting_300022	chr3_112603432_-	SINE	Alu	AluSx1
CAediting_300023	chr3_112603433_-	SINE	Alu	AluSx1
CAediting_300024	chr3_112603452_-	SINE	Alu	AluSx1
CAediting_300025	chr3_112603601_-	DNA	TcMar-Tigger	Tigger1
CAediting_300026	chr3_112606628_-	SINE	Alu	AluSz
CAediting_300027	chr3_112606697_-	SINE	Alu	AluSz
CAediting_300028	chr3_112606698_-	SINE	Alu	AluSz
CAediting_300029	chr3_112621241_-	LTR	ERVL-MaLR	MLT1H

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RNA A-to-I editing events in the alternative splicing sites for CCDC80

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000091986.14.CCDC80.

Correlation between RNA A-to-I editing and PSI for ENSG00000091986.14.CCDC80.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CCDC80

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for CCDC80

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for CCDC80

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1368054	chr19_46709310_-	ENSG00000091986.14	ENST00000439685	hsa-miR-320e	112605349	112605355	7mer-m8	112605348	112605365	140	-13.38

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CCDC80

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000206423.6	protein_coding
ENST00000439685.5	protein_coding

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_299948	ENST00000206423.6	chr3_112596962_-	-3716.00	-3716.00	-3790.80
CAediting_299949	ENST00000206423.6	chr3_112596984_-	-3716.10	-3716.00	-3790.80
CAediting_299950	ENST00000206423.6	chr3_112600526_-	-3716.00	-3716.00	-3790.80
CAediting_299951	ENST00000206423.6	chr3_112600527_-	-3722.40	-3716.00	-3790.80
CAediting_299952	ENST00000206423.6	chr3_112600554_-	-3715.60	-3716.00	-3790.80
CAediting_299953	ENST00000206423.6	chr3_112600557_-	-3716.40	-3716.00	-3790.80
CAediting_299954	ENST00000206423.6	chr3_112600559_-	-3715.60	-3716.00	-3790.80
CAediting_299955	ENST00000206423.6	chr3_112600578_-	-3715.30	-3716.00	-3790.80
CAediting_299956	ENST00000206423.6	chr3_112600585_-	-3715.10	-3716.00	-3790.80
CAediting_299957	ENST00000206423.6	chr3_112600591_-	-3715.10	-3716.00	-3790.80
CAediting_299958	ENST00000206423.6	chr3_112600594_-	-3718.60	-3716.00	-3790.80
CAediting_299959	ENST00000206423.6	chr3_112600599_-	-3715.00	-3716.00	-3790.80
CAediting_299960	ENST00000206423.6	chr3_112600607_-	-3716.00	-3716.00	-3790.80
CAediting_299961	ENST00000206423.6	chr3_112600610_-	-3715.10	-3716.00	-3790.80
CAediting_299962	ENST00000206423.6	chr3_112600612_-	-3722.60	-3716.00	-3790.80
CAediting_299963	ENST00000206423.6	chr3_112600616_-	-3722.60	-3716.00	-3790.80
CAediting_299964	ENST00000206423.6	chr3_112600623_-	-3719.70	-3716.00	-3790.80
CAediting_299965	ENST00000206423.6	chr3_112600626_-	-3715.30	-3716.00	-3790.80
CAediting_299966	ENST00000206423.6	chr3_112600630_-	-3713.00	-3716.00	-3790.80
CAediting_299967	ENST00000206423.6	chr3_112600634_-	-3715.30	-3716.00	-3790.80
CAediting_299968	ENST00000206423.6	chr3_112600657_-	-3715.30	-3716.00	-3790.80
CAediting_299969	ENST00000206423.6	chr3_112600669_-	-3717.10	-3716.00	-3790.80
CAediting_299970	ENST00000206423.6	chr3_112600670_-	-3715.70	-3716.00	-3790.80
CAediting_299971	ENST00000206423.6	chr3_112600672_-	-3716.10	-3716.00	-3790.80
CAediting_299972	ENST00000206423.6	chr3_112600673_-	-3716.10	-3716.00	-3790.80
CAediting_299973	ENST00000206423.6	chr3_112600676_-	-3716.00	-3716.00	-3790.80
CAediting_299974	ENST00000206423.6	chr3_112600678_-	-3716.00	-3716.00	-3790.80
CAediting_299975	ENST00000206423.6	chr3_112600679_-	-3716.10	-3716.00	-3790.80
CAediting_299976	ENST00000206423.6	chr3_112600680_-	-3716.10	-3716.00	-3790.80
CAediting_299977	ENST00000206423.6	chr3_112600681_-	-3716.10	-3716.00	-3790.80
CAediting_299978	ENST00000206423.6	chr3_112600697_-	-3716.00	-3716.00	-3790.80
CAediting_299979	ENST00000206423.6	chr3_112600699_-	-3715.90	-3716.00	-3790.80
CAediting_299980	ENST00000206423.6	chr3_112600700_-	-3720.20	-3716.00	-3790.80
CAediting_299981	ENST00000206423.6	chr3_112600705_-	-3716.00	-3716.00	-3790.80
CAediting_299982	ENST00000206423.6	chr3_112600707_-	-3716.00	-3716.00	-3790.80
CAediting_299983	ENST00000206423.6	chr3_112600717_-	-3715.30	-3716.00	-3790.80
CAediting_299984	ENST00000206423.6	chr3_112600720_-	-3715.40	-3716.00	-3790.80
CAediting_299985	ENST00000206423.6	chr3_112600755_-	-3722.00	-3716.00	-3790.80
CAediting_299986	ENST00000206423.6	chr3_112600776_-	-3716.00	-3716.00	-3790.80
CAediting_299987	ENST00000206423.6	chr3_112600777_-	-3716.10	-3716.00	-3790.80
CAediting_299988	ENST00000206423.6	chr3_112600783_-	-3719.80	-3716.00	-3790.80
CAediting_299989	ENST00000206423.6	chr3_112600785_-	-3714.70	-3716.00	-3790.80
CAediting_299990	ENST00000206423.6	chr3_112600793_-	-3716.00	-3716.00	-3790.80
CAediting_299991	ENST00000206423.6	chr3_112600803_-	-3722.20	-3716.00	-3790.80
CAediting_299992	ENST00000206423.6	chr3_112601574_-	-3717.90	-3716.00	-3790.80
CAediting_299993	ENST00000206423.6	chr3_112601575_-	-3716.00	-3716.00	-3790.80
CAediting_299994	ENST00000206423.6	chr3_112601583_-	-3716.40	-3716.00	-3790.80
CAediting_299995	ENST00000206423.6	chr3_112601596_-	-3716.90	-3716.00	-3790.80
CAediting_299996	ENST00000206423.6	chr3_112601597_-	-3716.00	-3716.00	-3790.80
CAediting_299997	ENST00000206423.6	chr3_112601599_-	-3717.00	-3716.00	-3790.80
CAediting_299998	ENST00000206423.6	chr3_112601600_-	-3716.20	-3716.00	-3790.80
CAediting_299999	ENST00000206423.6	chr3_112601601_-	-3716.00	-3716.00	-3790.80
CAediting_300000	ENST00000206423.6	chr3_112601611_-	-3716.00	-3716.00	-3790.80
CAediting_300001	ENST00000206423.6	chr3_112601615_-	-3716.00	-3716.00	-3790.80
CAediting_300002	ENST00000206423.6	chr3_112601616_-	-3716.50	-3716.00	-3790.80
CAediting_300003	ENST00000206423.6	chr3_112601632_-	-3719.10	-3716.00	-3790.80
CAediting_300004	ENST00000206423.6	chr3_112601638_-	-3717.80	-3716.00	-3790.80
CAediting_300005	ENST00000206423.6	chr3_112601641_-	-3716.20	-3716.00	-3790.80
CAediting_300006	ENST00000206423.6	chr3_112601657_-	-3717.30	-3716.00	-3790.80
CAediting_300007	ENST00000206423.6	chr3_112601675_-	-3715.60	-3716.00	-3790.80
CAediting_300008	ENST00000206423.6	chr3_112603264_-	-3720.20	-3716.00	-3790.80
CAediting_300009	ENST00000206423.6	chr3_112603270_-	-3716.00	-3716.00	-3790.80
CAediting_300010	ENST00000206423.6	chr3_112603282_-	-3715.70	-3716.00	-3790.80
CAediting_300011	ENST00000206423.6	chr3_112603283_-	-3716.10	-3716.00	-3790.80
CAediting_300012	ENST00000206423.6	chr3_112603284_-	-3715.70	-3716.00	-3790.80
CAediting_300013	ENST00000206423.6	chr3_112603303_-	-3719.60	-3716.00	-3790.80
CAediting_300014	ENST00000206423.6	chr3_112603327_-	-3721.30	-3716.00	-3790.80
CAediting_300015	ENST00000206423.6	chr3_112603335_-	-3719.60	-3716.00	-3790.80
CAediting_300016	ENST00000206423.6	chr3_112603349_-	-3715.70	-3716.00	-3790.80
CAediting_300017	ENST00000206423.6	chr3_112603352_-	-3717.10	-3716.00	-3790.80
CAediting_300018	ENST00000206423.6	chr3_112603391_-	-3715.30	-3716.00	-3790.80
CAediting_300019	ENST00000206423.6	chr3_112603393_-	-3715.00	-3716.00	-3790.80
CAediting_300020	ENST00000206423.6	chr3_112603397_-	-3719.90	-3716.00	-3790.80
CAediting_300021	ENST00000206423.6	chr3_112603406_-	-3715.00	-3716.00	-3790.80
CAediting_300022	ENST00000206423.6	chr3_112603432_-	-3715.70	-3716.00	-3790.80
CAediting_300023	ENST00000206423.6	chr3_112603433_-	-3715.70	-3716.00	-3790.80
CAediting_300024	ENST00000206423.6	chr3_112603452_-	-3722.30	-3716.00	-3790.80
CAediting_300025	ENST00000206423.6	chr3_112603601_-	-3715.80	-3716.00	-3790.80
CAediting_300030	ENST00000206423.6	chr3_112638419_-	-3716.30	-3716.00	-3790.80
CAediting_300030	ENST00000439685.5	chr3_112638419_-	-1143.50	-1143.90	-1143.50

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Relation with ADAR for CCDC80

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LUSC	CAediting_299955	chr3_112600578_-	.	.	.	.	0.0138649125761562	0.253046859089997
LGG	CAediting_299963	chr3_112600616_-	.	.	.	.	0.00682055180065407	0.145621460713862
LUAD	CAediting_299963	chr3_112600616_-	0.0477064828806041	0.156790511436403	.	.	.	.
LUSC	CAediting_299963	chr3_112600616_-	0.000616319701637026	0.280111985063847	.	.	.	.
SKCM	CAediting_299963	chr3_112600616_-	0.0454509441013211	0.252983774988963	.	.	.	.
MESO	CAediting_299963	chr3_112600616_-	3.84546842155591e-05	0.483926121596649	.	.	0.00365115833884976	0.352956371305168
SARC	CAediting_299963	chr3_112600616_-	2.81900256584749e-07	0.441683903815951	.	.	.	.
LGG	CAediting_299968	chr3_112600657_-	.	.	.	.	0.00322734968172817	0.165195915594261
BRCA	CAediting_299968	chr3_112600657_-	0.00410553175730725	0.122083060081329	.	.	.	.
GBM	CAediting_299968	chr3_112600657_-	0.00503591506910175	0.30332091928016	.	.	0.0402437848002329	0.224308885929585
STAD	CAediting_299968	chr3_112600657_-	.	.	0.041395117623541	0.169030738742111	.	.
SKCM	CAediting_299968	chr3_112600657_-	0.00377239025238781	0.322285620613658	.	.	.	.
MESO	CAediting_299968	chr3_112600657_-	1.96538830800369e-05	0.486366898603438	.	.	.	.
SARC	CAediting_299968	chr3_112600657_-	2.50162922381995e-11	0.514974036994476	.	.	.	.
LGG	CAediting_299988	chr3_112600783_-	.	.	0.000545259287474359	0.289565570937444	.	.
BRCA	CAediting_299988	chr3_112600783_-	0.0220270315193319	0.116988835220499	.	.	.	.
BRCA	CAediting_299996	chr3_112601597_-	.	.	0.00354398923803075	0.370753175229351	.	.
GBM	CAediting_299997	chr3_112601599_-	0.0272932408601964	0.275969242300178	.	.	.	.
STAD	CAediting_299997	chr3_112601599_-	0.0353339071393825	0.180640354234815	.	.	.	.
SARC	CAediting_299997	chr3_112601599_-	0.0438246403896931	0.25691615522942	.	.	.	.
LGG	CAediting_300000	chr3_112601611_-	0.00220787555085075	0.178442175228091	.	.	.	.
BRCA	CAediting_300000	chr3_112601611_-	1.27171694744666e-06	0.199714929802542	.	.	.	.
LUSC	CAediting_300000	chr3_112601611_-	0.015640181368001	0.174702435160659	.	.	.	.
GBM	CAediting_300000	chr3_112601611_-	0.00101739287710104	0.323741726428777	0.0369178792302377	0.2089845395915	.	.
HNSC	CAediting_300000	chr3_112601611_-	0.0398379776418176	0.210184706662938	.	.	.	.
STAD	CAediting_300000	chr3_112601611_-	0.0120287259190337	0.180453131209823	.	.	.	.
THCA	CAediting_300000	chr3_112601611_-	4.37780460067108e-10	0.38735420854962	.	.	.	.
KIRC	CAediting_300000	chr3_112601611_-	0.000661350217250712	0.311621617165498	.	.	.	.
OV	CAediting_300000	chr3_112601611_-	0.0117534527825137	0.235240395218737	.	.	.	.
SARC	CAediting_300000	chr3_112601611_-	0.000280189503483324	0.294474748164897	.	.	.	.
GBM	CAediting_300004	chr3_112601638_-	0.0329192317179501	0.244997726191133	.	.	.	.
OV	CAediting_300004	chr3_112601638_-	0.0099443872581921	0.28663859202649	.	.	.	.
STAD	CAediting_300008	chr3_112603264_-	.	.	.	.	0.0261946892441475	0.256718893647307

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Relation with cancer stages for CCDC80

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
KIRC	pathologic_stage	CAediting_300000	chr3_112601611_-	0.0212286946189887	-0.213747371288987
OV	clinical_stage	CAediting_299988	chr3_112600783_-	0.0305731059959565	0.300238430097761
STAD	pathologic_stage	CAediting_300004	chr3_112601638_-	0.00627864621370218	0.241294073196759

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Relation with survival for CCDC80

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
LGG	CAediting_299968	chr3_112600657_-	0.00984563464991717	0.00389652	0.0771836

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RelatedDrugs for CCDC80

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for CCDC80

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
CCDC80	C0011615	Dermatitis, Atopic	1	CTD_human
CCDC80	C0019193	Hepatitis, Toxic	1	CTD_human
CCDC80	C0086196	Eczema, Infantile	1	CTD_human
CCDC80	C0860207	Drug-Induced Liver Disease	1	CTD_human
CCDC80	C1262760	Hepatitis, Drug-Induced	1	CTD_human
CCDC80	C3658290	Drug-Induced Acute Liver Injury	1	CTD_human
CCDC80	C4277682	Chemical and Drug Induced Liver Injury	1	CTD_human
CCDC80	C4279912	Chemically-Induced Liver Toxicity	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene