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Editing gene: NFAM1 (CAeditome ID:150372)

Gene summary for NFAM1

Gene summary

Gene information	Gene symbol	NFAM1
	Gene ID	150372
	Gene name	NFAT activating protein with ITAM motif 1
	Synonyms	CNAIP
	Cytomap	22q13.2
	Type of gene	protein-coding
	Description	NFAT activation molecule 1calcineurin/NFAT-activating ITAM-containing protein
	Modification date	20210518
	UniProtAcc	Q8NET5
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
NFAM1	GO:0004888	NFAT activation molecule 1	12615919
NFAM1	GO:0007165	NFAT activation molecule 1	12615919
NFAM1	GO:0035556	NFAT activation molecule 1	12615919
NFAM1	GO:0051091	NFAT activation molecule 1	12615919
NFAM1	GO:0016021	NFAT activation molecule 1	12615919

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RNA A-to-I events for NFAM1

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000235568.5

RNA A-to-I editing events in Cancer.

CAediting_1489776(42381081, -), CAediting_1489777(42381099, -), CAediting_1489778(42381119, -), CAediting_1489779(42381126, -), CAediting_1489780(42381131, -), CAediting_1489781(42381147, -), CAediting_1489782(42381152, -), CAediting_1489783(42381172, -), CAediting_1489784(42381180, -), CAediting_1489785(42381184, -), CAediting_1489786(42381188, -), CAediting_1489787(42381189, -), CAediting_1489788(42381191, -), CAediting_1489789(42381203, -), CAediting_1489790(42381215, -), CAediting_1489791(42381228, -), CAediting_1489792(42381229, -), CAediting_1489793(42381238, -), CAediting_1489794(42381251, -), CAediting_1489795(42381263, -), CAediting_1489796(42381276, -), CAediting_1489797(42381279, -), CAediting_1489798(42381347, -), CAediting_1489799(42381370, -), CAediting_1489800(42381374, -), CAediting_1489801(42382057, -), CAediting_1489802(42382089, -), CAediting_1489803(42382141, -), CAediting_1489804(42382143, -), CAediting_1489805(42382179, -), CAediting_1489806(42382188, -), CAediting_1489807(42382194, -), CAediting_1489808(42382200, -), CAediting_1489809(42382220, -), CAediting_1489810(42382229, -), CAediting_1489811(42382251, -), CAediting_1489812(42382328, -), CAediting_1489813(42382329, -), CAediting_1489814(42382831, -), CAediting_1489815(42382839, -), CAediting_1489816(42382862, -), CAediting_1489817(42382870, -), CAediting_1489818(42383205, -), CAediting_1489819(42383426, -), CAediting_1489820(42383436, -), CAediting_1489821(42383443, -), CAediting_1489822(42383459, -), CAediting_1489823(42383460, -), CAediting_1489824(42383466, -), CAediting_1489825(42383470, -), CAediting_1489826(42383471, -), CAediting_1489827(42383473, -), CAediting_1489828(42383484, -), CAediting_1489829(42383495, -), CAediting_1489830(42383496, -), CAediting_1489831(42383503, -), CAediting_1489832(42383505, -), CAediting_1489833(42383509, -), CAediting_1489834(42383533, -), CAediting_1489835(42383534, -), CAediting_1489836(42383549, -), CAediting_1489837(42383554, -), CAediting_1489838(42383556, -), CAediting_1489839(42383570, -), CAediting_1489840(42383572, -), CAediting_1489841(42383575, -), CAediting_1489842(42383583, -), CAediting_1489843(42383600, -), CAediting_1489844(42383604, -), CAediting_1489845(42383606, -), CAediting_1489846(42383612, -), CAediting_1489847(42383618, -), CAediting_1489848(42383620, -), CAediting_1489849(42383629, -), CAediting_1489850(42383631, -), CAediting_1489851(42383647, -), CAediting_1489852(42383648, -), CAediting_1489853(42383652, -), CAediting_1489854(42383671, -), CAediting_1489855(42383688, -), CAediting_1489856(42383741, -), CAediting_1489857(42394469, -), CAediting_1489858(42398510, -), CAediting_1489859(42398518, -), CAediting_1489860(42398528, -), CAediting_1489861(42398537, -), CAediting_1489862(42398545, -), CAediting_1489863(42398551, -), CAediting_1489864(42400361, -), CAediting_1489865(42400496, -), CAediting_1489866(42400612, -), CAediting_1489867(42402908, -), CAediting_1489868(42402932, -), CAediting_1489869(42402933, -), CAediting_1489870(42402934, -), CAediting_1489871(42402941, -), CAediting_1489872(42402944, -), CAediting_1489873(42402946, -), CAediting_1489874(42402972, -), CAediting_1489875(42402973, -), CAediting_1489876(42403043, -), CAediting_1489877(42403067, -), CAediting_1489878(42403118, -), CAediting_1489879(42405184, -), CAediting_1489880(42406873, -), CAediting_1489881(42406885, -), CAediting_1489882(42406896, -), CAediting_1489883(42406899, -), CAediting_1489884(42407193, -), CAediting_1489885(42407434, -), CAediting_1489886(42407506, -), CAediting_1489887(42407507, -), CAediting_1489888(42407517, -), CAediting_1489889(42407529, -), CAediting_1489890(42407710, -), CAediting_1489891(42407851, -), CAediting_1489892(42407883, -), CAediting_1489893(42407938, -), CAediting_1489894(42407942, -), CAediting_1489895(42408008, -), CAediting_1489896(42408089, -), CAediting_1489897(42408090, -), CAediting_1489898(42408121, -), CAediting_1489899(42410442, -), CAediting_1489900(42410550, -), CAediting_1489901(42410551, -), CAediting_1489902(42410566, -), CAediting_1489903(42411121, -), CAediting_1489904(42415392, -), CAediting_1489905(42415408, -), CAediting_1489906(42415421, -), CAediting_1489907(42420107, -), CAediting_1489908(42420108, -), CAediting_1489909(42420131, -), CAediting_1489910(42420143, -), CAediting_1489911(42420148, -), CAediting_1489912(42420149, -), CAediting_1489913(42420171, -), CAediting_1489914(42420175, -), CAediting_1489915(42420187, -), CAediting_1489916(42420192, -), CAediting_1489917(42420287, -), CAediting_1489918(42424251, -), CAediting_1489919(42425019, -), CAediting_1489920(42425066, -), CAediting_1489921(42425201, -), CAediting_1489922(42428580, -),

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RNA editing positional annotations for NFAM1 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1489776	chr22_42381081_-	UTR3
CAediting_1489777	chr22_42381099_-	UTR3
CAediting_1489778	chr22_42381119_-	UTR3
CAediting_1489779	chr22_42381126_-	UTR3
CAediting_1489780	chr22_42381131_-	UTR3
CAediting_1489781	chr22_42381147_-	UTR3
CAediting_1489782	chr22_42381152_-	UTR3
CAediting_1489783	chr22_42381172_-	UTR3
CAediting_1489784	chr22_42381180_-	UTR3
CAediting_1489785	chr22_42381184_-	UTR3
CAediting_1489786	chr22_42381188_-	UTR3
CAediting_1489787	chr22_42381189_-	UTR3
CAediting_1489788	chr22_42381191_-	UTR3
CAediting_1489789	chr22_42381203_-	UTR3
CAediting_1489790	chr22_42381215_-	UTR3
CAediting_1489791	chr22_42381228_-	UTR3
CAediting_1489792	chr22_42381229_-	UTR3
CAediting_1489793	chr22_42381238_-	UTR3
CAediting_1489794	chr22_42381251_-	UTR3
CAediting_1489795	chr22_42381263_-	UTR3
CAediting_1489796	chr22_42381276_-	UTR3
CAediting_1489797	chr22_42381279_-	UTR3
CAediting_1489798	chr22_42381347_-	UTR3
CAediting_1489799	chr22_42381370_-	UTR3
CAediting_1489800	chr22_42381374_-	UTR3
CAediting_1489801	chr22_42382057_-	UTR3
CAediting_1489802	chr22_42382089_-	UTR3
CAediting_1489803	chr22_42382141_-	UTR3
CAediting_1489804	chr22_42382143_-	UTR3
CAediting_1489805	chr22_42382179_-	UTR3
CAediting_1489806	chr22_42382188_-	UTR3
CAediting_1489807	chr22_42382194_-	UTR3
CAediting_1489808	chr22_42382200_-	UTR3
CAediting_1489809	chr22_42382220_-	UTR3
CAediting_1489810	chr22_42382229_-	UTR3
CAediting_1489811	chr22_42382251_-	UTR3
CAediting_1489812	chr22_42382328_-	UTR3
CAediting_1489813	chr22_42382329_-	UTR3
CAediting_1489814	chr22_42382831_-	UTR3
CAediting_1489815	chr22_42382839_-	UTR3
CAediting_1489816	chr22_42382862_-	UTR3
CAediting_1489817	chr22_42382870_-	UTR3
CAediting_1489818	chr22_42383205_-	UTR3
CAediting_1489819	chr22_42383426_-	UTR3
CAediting_1489820	chr22_42383436_-	UTR3
CAediting_1489821	chr22_42383443_-	UTR3
CAediting_1489822	chr22_42383459_-	UTR3
CAediting_1489823	chr22_42383460_-	UTR3
CAediting_1489824	chr22_42383466_-	UTR3
CAediting_1489825	chr22_42383470_-	UTR3
CAediting_1489826	chr22_42383471_-	UTR3
CAediting_1489827	chr22_42383473_-	UTR3
CAediting_1489828	chr22_42383484_-	UTR3
CAediting_1489829	chr22_42383495_-	UTR3
CAediting_1489830	chr22_42383496_-	UTR3
CAediting_1489831	chr22_42383503_-	UTR3
CAediting_1489832	chr22_42383505_-	UTR3
CAediting_1489833	chr22_42383509_-	UTR3
CAediting_1489834	chr22_42383533_-	UTR3
CAediting_1489835	chr22_42383534_-	UTR3
CAediting_1489836	chr22_42383549_-	UTR3
CAediting_1489837	chr22_42383554_-	UTR3
CAediting_1489838	chr22_42383556_-	UTR3
CAediting_1489839	chr22_42383570_-	UTR3
CAediting_1489840	chr22_42383572_-	UTR3
CAediting_1489841	chr22_42383575_-	UTR3
CAediting_1489842	chr22_42383583_-	UTR3
CAediting_1489843	chr22_42383600_-	UTR3
CAediting_1489844	chr22_42383604_-	UTR3
CAediting_1489845	chr22_42383606_-	UTR3
CAediting_1489846	chr22_42383612_-	UTR3
CAediting_1489847	chr22_42383618_-	UTR3
CAediting_1489848	chr22_42383620_-	UTR3
CAediting_1489849	chr22_42383629_-	UTR3
CAediting_1489850	chr22_42383631_-	UTR3
CAediting_1489851	chr22_42383647_-	UTR3
CAediting_1489852	chr22_42383648_-	UTR3
CAediting_1489853	chr22_42383652_-	UTR3
CAediting_1489854	chr22_42383671_-	UTR3
CAediting_1489855	chr22_42383688_-	UTR3
CAediting_1489856	chr22_42383741_-	UTR3
CAediting_1489857	chr22_42394469_-	intronic
CAediting_1489858	chr22_42398510_-	intronic
CAediting_1489859	chr22_42398518_-	intronic
CAediting_1489860	chr22_42398528_-	intronic
CAediting_1489861	chr22_42398537_-	intronic
CAediting_1489862	chr22_42398545_-	intronic
CAediting_1489863	chr22_42398551_-	intronic
CAediting_1489864	chr22_42400361_-	intronic
CAediting_1489865	chr22_42400496_-	intronic
CAediting_1489866	chr22_42400612_-	intronic
CAediting_1489867	chr22_42402908_-	intronic
CAediting_1489868	chr22_42402932_-	intronic
CAediting_1489869	chr22_42402933_-	intronic
CAediting_1489870	chr22_42402934_-	intronic
CAediting_1489871	chr22_42402941_-	intronic
CAediting_1489872	chr22_42402944_-	intronic
CAediting_1489873	chr22_42402946_-	intronic
CAediting_1489874	chr22_42402972_-	intronic
CAediting_1489875	chr22_42402973_-	intronic
CAediting_1489876	chr22_42403043_-	intronic
CAediting_1489877	chr22_42403067_-	intronic
CAediting_1489878	chr22_42403118_-	intronic
CAediting_1489879	chr22_42405184_-	intronic
CAediting_1489880	chr22_42406873_-	intronic
CAediting_1489881	chr22_42406885_-	intronic
CAediting_1489882	chr22_42406896_-	intronic
CAediting_1489883	chr22_42406899_-	intronic
CAediting_1489884	chr22_42407193_-	intronic
CAediting_1489885	chr22_42407434_-	intronic
CAediting_1489886	chr22_42407506_-	intronic
CAediting_1489887	chr22_42407507_-	intronic
CAediting_1489888	chr22_42407517_-	intronic
CAediting_1489889	chr22_42407529_-	intronic
CAediting_1489890	chr22_42407710_-	intronic
CAediting_1489891	chr22_42407851_-	intronic
CAediting_1489892	chr22_42407883_-	intronic
CAediting_1489893	chr22_42407938_-	intronic
CAediting_1489894	chr22_42407942_-	intronic
CAediting_1489895	chr22_42408008_-	intronic
CAediting_1489896	chr22_42408089_-	intronic
CAediting_1489897	chr22_42408090_-	intronic
CAediting_1489898	chr22_42408121_-	intronic
CAediting_1489899	chr22_42410442_-	UTR3
CAediting_1489900	chr22_42410550_-	intronic
CAediting_1489901	chr22_42410551_-	intronic
CAediting_1489902	chr22_42410566_-	intronic
CAediting_1489903	chr22_42411121_-	intronic
CAediting_1489904	chr22_42415392_-	intronic
CAediting_1489905	chr22_42415408_-	intronic
CAediting_1489906	chr22_42415421_-	intronic
CAediting_1489907	chr22_42420107_-	intronic
CAediting_1489908	chr22_42420108_-	intronic
CAediting_1489909	chr22_42420131_-	intronic
CAediting_1489910	chr22_42420143_-	intronic
CAediting_1489911	chr22_42420148_-	intronic
CAediting_1489912	chr22_42420149_-	intronic
CAediting_1489913	chr22_42420171_-	intronic
CAediting_1489914	chr22_42420175_-	intronic
CAediting_1489915	chr22_42420187_-	intronic
CAediting_1489916	chr22_42420192_-	intronic
CAediting_1489917	chr22_42420287_-	intronic
CAediting_1489918	chr22_42424251_-	intronic
CAediting_1489919	chr22_42425019_-	intronic
CAediting_1489920	chr22_42425066_-	intronic
CAediting_1489921	chr22_42425201_-	intronic
CAediting_1489922	chr22_42428580_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1489801	chr22_42382057_-	SINE	Alu	AluSz
CAediting_1489802	chr22_42382089_-	SINE	Alu	AluSz
CAediting_1489803	chr22_42382141_-	SINE	Alu	AluSz
CAediting_1489804	chr22_42382143_-	SINE	Alu	AluSz
CAediting_1489805	chr22_42382179_-	SINE	Alu	AluSz
CAediting_1489806	chr22_42382188_-	SINE	Alu	AluSz
CAediting_1489807	chr22_42382194_-	SINE	Alu	AluSz
CAediting_1489808	chr22_42382200_-	SINE	Alu	AluSz
CAediting_1489809	chr22_42382220_-	SINE	Alu	AluSz
CAediting_1489810	chr22_42382229_-	SINE	Alu	AluSz
CAediting_1489811	chr22_42382251_-	SINE	Alu	AluSz
CAediting_1489812	chr22_42382328_-	SINE	Alu	AluSz
CAediting_1489813	chr22_42382329_-	SINE	Alu	AluSz
CAediting_1489814	chr22_42382831_-	Simple_repeat	Simple_repeat	(CTC)n
CAediting_1489857	chr22_42394469_-	SINE	Alu	FLAM_A
CAediting_1489858	chr22_42398510_-	SINE	Alu	AluSx
CAediting_1489859	chr22_42398518_-	SINE	Alu	AluSx
CAediting_1489860	chr22_42398528_-	SINE	Alu	AluSx
CAediting_1489861	chr22_42398537_-	SINE	Alu	AluSx
CAediting_1489862	chr22_42398545_-	SINE	Alu	AluSx
CAediting_1489863	chr22_42398551_-	SINE	Alu	AluSx
CAediting_1489864	chr22_42400361_-	SINE	Alu	AluSq2
CAediting_1489865	chr22_42400496_-	SINE	Alu	AluSq2
CAediting_1489866	chr22_42400612_-	SINE	Alu	AluSq2
CAediting_1489867	chr22_42402908_-	SINE	Alu	AluSg7
CAediting_1489868	chr22_42402932_-	SINE	Alu	AluSg7
CAediting_1489869	chr22_42402933_-	SINE	Alu	AluSg7
CAediting_1489870	chr22_42402934_-	SINE	Alu	AluSg7
CAediting_1489871	chr22_42402941_-	SINE	Alu	AluSg7
CAediting_1489872	chr22_42402944_-	SINE	Alu	AluSg7
CAediting_1489873	chr22_42402946_-	SINE	Alu	AluSg7
CAediting_1489874	chr22_42402972_-	SINE	Alu	AluSg7
CAediting_1489875	chr22_42402973_-	SINE	Alu	AluSg7
CAediting_1489876	chr22_42403043_-	SINE	Alu	AluSg7
CAediting_1489877	chr22_42403067_-	SINE	Alu	AluSg7
CAediting_1489878	chr22_42403118_-	SINE	Alu	AluSg7
CAediting_1489880	chr22_42406873_-	SINE	Alu	AluSc8
CAediting_1489881	chr22_42406885_-	SINE	Alu	AluSc8
CAediting_1489882	chr22_42406896_-	SINE	Alu	AluSc8
CAediting_1489883	chr22_42406899_-	SINE	Alu	AluSc8
CAediting_1489884	chr22_42407193_-	SINE	Alu	AluSz6
CAediting_1489885	chr22_42407434_-	SINE	Alu	AluSx1
CAediting_1489886	chr22_42407506_-	SINE	Alu	AluSx1
CAediting_1489887	chr22_42407507_-	SINE	Alu	AluSx1
CAediting_1489888	chr22_42407517_-	SINE	Alu	AluSx1
CAediting_1489889	chr22_42407529_-	SINE	Alu	AluSx1
CAediting_1489890	chr22_42407710_-	SINE	Alu	AluJr
CAediting_1489891	chr22_42407851_-	SINE	Alu	AluJr
CAediting_1489892	chr22_42407883_-	SINE	Alu	AluJr
CAediting_1489893	chr22_42407938_-	SINE	Alu	AluSx1
CAediting_1489894	chr22_42407942_-	SINE	Alu	AluSx1
CAediting_1489895	chr22_42408008_-	SINE	Alu	AluSx1
CAediting_1489896	chr22_42408089_-	SINE	Alu	AluSx1
CAediting_1489897	chr22_42408090_-	SINE	Alu	AluSx1
CAediting_1489898	chr22_42408121_-	SINE	Alu	AluSx1
CAediting_1489899	chr22_42410442_-	SINE	Alu	AluSx1
CAediting_1489900	chr22_42410550_-	SINE	Alu	AluSx1
CAediting_1489901	chr22_42410551_-	SINE	Alu	AluSx1
CAediting_1489902	chr22_42410566_-	SINE	Alu	AluSx1
CAediting_1489903	chr22_42411121_-	SINE	Alu	AluSq2
CAediting_1489904	chr22_42415392_-	SINE	Alu	AluY
CAediting_1489905	chr22_42415408_-	SINE	Alu	AluY
CAediting_1489906	chr22_42415421_-	SINE	Alu	AluY
CAediting_1489907	chr22_42420107_-	SINE	Alu	AluSq2
CAediting_1489908	chr22_42420108_-	SINE	Alu	AluSq2
CAediting_1489909	chr22_42420131_-	SINE	Alu	AluSq2
CAediting_1489910	chr22_42420143_-	SINE	Alu	AluSq2
CAediting_1489911	chr22_42420148_-	SINE	Alu	AluSq2
CAediting_1489912	chr22_42420149_-	SINE	Alu	AluSq2
CAediting_1489913	chr22_42420171_-	SINE	Alu	AluSq2
CAediting_1489914	chr22_42420175_-	SINE	Alu	AluSq2
CAediting_1489915	chr22_42420187_-	SINE	Alu	AluSq2
CAediting_1489916	chr22_42420192_-	SINE	Alu	AluSq2
CAediting_1489917	chr22_42420287_-	SINE	Alu	AluJo
CAediting_1489918	chr22_42424251_-	SINE	Alu	AluY
CAediting_1489919	chr22_42425019_-	SINE	Alu	AluSx
CAediting_1489920	chr22_42425066_-	SINE	Alu	AluSx
CAediting_1489921	chr22_42425201_-	SINE	Alu	AluSx
CAediting_1489922	chr22_42428580_-	SINE	Alu	AluSx

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RNA A-to-I editing events in the alternative splicing sites for NFAM1

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
IR	CAediting_1489777	chr22_42381099_-	42381084:42381106	3SS	0+13i	GGAGGTCAGTCTGTGCCCAGCCT	-2.34	GGAGGTCGGTCTGTGCCCAGCCT	1.36
IR	CAediting_1489854	chr22_42383671_-	42383663:42383671	5SS	3+0i	AGGTCATGC	-8.79	GGGTCATGC	-10.1

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000235568.5.NFAM1.

Correlation between RNA A-to-I editing and PSI for ENSG00000235568.5.NFAM1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for NFAM1

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for NFAM1

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for NFAM1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for NFAM1

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for NFAM1

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BRCA	CAediting_1489777	chr22_42381099_-	0.0155451106311649	0.186970918364279	.	.	.	.
SKCM	CAediting_1489794	chr22_42381251_-	.	.	.	.	0.012015360314167	0.300828527630402
KIRC	CAediting_1489829	chr22_42383495_-	.	.	0.0188615327643908	0.22260226866356	.	.
OV	CAediting_1489829	chr22_42383495_-	.	.	.	.	0.027124059037836	0.23168365304906
KIRC	CAediting_1489834	chr22_42383533_-	0.0289333201311651	0.151863783423037	.	.	.	.
OV	CAediting_1489834	chr22_42383533_-	0.0167952193584268	0.228625263222135	.	.	.	.
BRCA	CAediting_1489835	chr22_42383534_-	0.012452948547313	0.165271774722746	.	.	.	.
CESC	CAediting_1489835	chr22_42383534_-	.	.	.	.	0.0122636690653581	0.344959211400581
KIRC	CAediting_1489835	chr22_42383534_-	.	.	0.0216473068638574	0.169691845129513	0.0381515895879589	0.153399853336091
OV	CAediting_1489842	chr22_42383583_-	.	.	0.0376079922215571	0.230041005526717	.	.
SKCM	CAediting_1489850	chr22_42383631_-	.	.	0.033049743360785	0.152333158281811	.	.
TGCT	CAediting_1489850	chr22_42383631_-	.	.	9.19933708729884e-05	0.425660666136409	.	.
THYM	CAediting_1489850	chr22_42383631_-	0.0109820860982678	0.311185625247449	.	.	.	.
BRCA	CAediting_1489851	chr22_42383647_-	0.00602705868574378	0.160089153025833	.	.	.	.
GBM	CAediting_1489851	chr22_42383647_-	0.00704270585986266	0.365951736872378	.	.	.	.
SARC	CAediting_1489851	chr22_42383647_-	0.000490379848407458	0.350855898200326	.	.	.	.

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Relation with cancer stages for NFAM1

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
CESC	clinical_stage	CAediting_1489834	chr22_42383533_-	0.0204538205460345	-0.327004981776732
CESC	clinical_stage	CAediting_1489835	chr22_42383534_-	0.002835335981561	-0.409634705532421
KIRC	pathologic_stage	CAediting_1489835	chr22_42383534_-	0.00697308957318803	-0.199906716677634
KIRC	pathologic_stage	CAediting_1489842	chr22_42383583_-	0.0396877535664864	-0.212574611816444
KIRC	pathologic_stage	CAediting_1489850	chr22_42383631_-	4.35016610808164e-05	-0.207293780728886
KIRC	pathologic_stage	CAediting_1489851	chr22_42383647_-	0.0150960377154144	-0.175160754380542
KIRP	clinical_stage	CAediting_1489851	chr22_42383647_-	0.0201744907776668	-0.34916764299883
LUAD	pathologic_stage	CAediting_1489850	chr22_42383631_-	0.0285027592781241	-0.124822752061416
PAAD	pathologic_stage	CAediting_1489835	chr22_42383534_-	0.0041830348423907	-0.373774663124599
TGCT	clinical_stage	CAediting_1489850	chr22_42383631_-	0.00892139674026766	0.394119607034661
TGCT	pathologic_stage	CAediting_1489850	chr22_42383631_-	0.0418600737154224	0.304665835445319

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Relation with survival for NFAM1

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
BRCA	CAediting_1489835	chr22_42383534_-	0.0146787717980301	0.0307755	0.00626641
GBM	CAediting_1489850	chr22_42383631_-	0.0131320170526903	0.0263679	0.112833
HNSC	CAediting_1489832	chr22_42383505_-	0.0275895461692273	0.013851	0.00239496
KIRC	CAediting_1489851	chr22_42383647_-	0.00107238933647691	0.0397727	57.0475

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RelatedDrugs for NFAM1

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for NFAM1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene