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Editing gene: CSF3R (CAeditome ID:1441)

Gene summary for CSF3R

Gene summary

Gene information	Gene symbol	CSF3R
	Gene ID	1441
	Gene name	colony stimulating factor 3 receptor
	Synonyms	CD114\|GCSFR\|SCN7
	Cytomap	1p34.3
	Type of gene	protein-coding
	Description	granulocyte colony-stimulating factor receptorCD114 antigenG-CSF receptorG-CSF-Rcolony stimulating factor 3 receptor (granulocyte)
	Modification date	20210518
	UniProtAcc	Q99062
	Context	- 28652245(Unpaired Extracellular Cysteine Mutations of CSF3R Mediate Gain or Loss of Function)

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for CSF3R

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000119535.16

RNA A-to-I editing events in Cancer.

CAediting_46735(36468769, -), CAediting_46736(36468827, -), CAediting_46737(36468833, -), CAediting_46738(36468834, -), CAediting_46739(36468840, -), CAediting_46740(36470287, -), CAediting_46741(36475011, -), CAediting_46742(36475012, -), CAediting_46743(36476670, -), CAediting_46744(36476744, -), CAediting_46745(36476745, -), CAediting_46746(36476753, -), CAediting_46747(36476758, -), CAediting_46748(36476763, -), CAediting_46749(36476768, -), CAediting_46750(36476776, -), CAediting_46751(36476785, -), CAediting_46752(36476799, -), CAediting_46753(36476821, -), CAediting_46754(36476825, -), CAediting_46755(36476829, -), CAediting_46756(36476830, -), CAediting_46757(36476831, -), CAediting_46758(36476832, -), CAediting_46759(36476833, -), CAediting_46760(36476839, -), CAediting_46761(36476840, -), CAediting_46762(36476843, -), CAediting_46763(36476845, -), CAediting_46764(36476863, -), CAediting_46765(36476869, -), CAediting_46766(36476873, -), CAediting_46767(36476888, -), CAediting_46768(36476889, -), CAediting_46769(36476913, -), CAediting_46770(36476916, -), CAediting_46771(36476919, -), CAediting_46772(36476920, -), CAediting_46773(36476926, -), CAediting_46774(36476943, -), CAediting_46775(36476949, -), CAediting_46776(36476959, -), CAediting_46777(36476961, -), CAediting_46778(36477294, -), CAediting_46779(36477331, -), CAediting_46780(36477335, -), CAediting_46781(36477355, -), CAediting_46782(36477356, -), CAediting_46783(36477397, -), CAediting_46784(36477423, -), CAediting_46785(36477426, -), CAediting_46786(36477427, -), CAediting_46787(36477428, -), CAediting_46788(36477478, -), CAediting_46789(36477480, -), CAediting_46790(36477549, -), CAediting_46791(36477568, -), CAediting_46792(36477571, -), CAediting_46793(36477797, -), CAediting_46794(36477811, -), CAediting_46795(36477816, -), CAediting_46796(36477821, -), CAediting_46797(36477826, -), CAediting_46798(36477831, -), CAediting_46799(36477832, -), CAediting_46800(36477848, -), CAediting_46801(36477851, -), CAediting_46802(36477856, -), CAediting_46803(36477870, -), CAediting_46804(36477874, -), CAediting_46805(36477887, -), CAediting_46806(36477891, -), CAediting_46807(36477897, -), CAediting_46808(36477923, -), CAediting_46809(36477927, -), CAediting_46810(36477933, -), CAediting_46811(36477953, -), CAediting_46812(36477954, -), CAediting_46813(36477959, -), CAediting_46814(36477961, -), CAediting_46815(36477992, -), CAediting_46816(36478022, -), CAediting_46817(36478025, -), CAediting_46818(36478030, -), CAediting_46819(36478031, -), CAediting_46820(36478266, -), CAediting_46821(36478270, -), CAediting_46822(36478272, -), CAediting_46823(36478284, -), CAediting_46824(36478285, -), CAediting_46825(36478286, -), CAediting_46826(36478346, -), CAediting_46827(36478407, -), CAediting_46828(36478417, -), CAediting_46829(36478472, -), CAediting_46830(36478477, -), CAediting_46831(36478493, -), CAediting_46832(36478496, -), CAediting_46833(36478497, -), CAediting_46834(36478527, -), CAediting_46835(36478588, -), CAediting_46836(36478589, -), CAediting_46837(36478591, -), CAediting_46838(36478600, -), CAediting_46839(36478603, -), CAediting_46840(36478604, -), CAediting_46841(36478605, -), CAediting_46842(36478643, -), CAediting_46843(36478645, -), CAediting_46844(36478674, -), CAediting_46845(36478682, -), CAediting_46846(36478719, -), CAediting_46847(36478721, -), CAediting_46848(36478724, -), CAediting_46849(36478739, -), CAediting_46850(36478769, -), CAediting_46851(36478782, -), CAediting_46852(36478783, -), CAediting_46853(36478789, -), CAediting_46854(36478794, -), CAediting_46855(36478799, -), CAediting_46856(36478804, -), CAediting_46857(36478805, -), CAediting_46858(36478845, -), CAediting_46859(36478847, -),

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RNA editing positional annotations for CSF3R using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_46735	chr1_36468769_-	ncRNA_exonic
CAediting_46736	chr1_36468827_-	ncRNA_exonic
CAediting_46737	chr1_36468833_-	ncRNA_exonic
CAediting_46738	chr1_36468834_-	ncRNA_exonic
CAediting_46739	chr1_36468840_-	ncRNA_exonic
CAediting_46740	chr1_36470287_-	ncRNA_intronic
CAediting_46741	chr1_36475011_-	ncRNA_intronic
CAediting_46742	chr1_36475012_-	ncRNA_intronic
CAediting_46743	chr1_36476670_-	intronic
CAediting_46744	chr1_36476744_-	intronic
CAediting_46745	chr1_36476745_-	intronic
CAediting_46746	chr1_36476753_-	intronic
CAediting_46747	chr1_36476758_-	intronic
CAediting_46748	chr1_36476763_-	intronic
CAediting_46749	chr1_36476768_-	intronic
CAediting_46750	chr1_36476776_-	intronic
CAediting_46751	chr1_36476785_-	intronic
CAediting_46752	chr1_36476799_-	intronic
CAediting_46753	chr1_36476821_-	intronic
CAediting_46754	chr1_36476825_-	intronic
CAediting_46755	chr1_36476829_-	intronic
CAediting_46756	chr1_36476830_-	intronic
CAediting_46757	chr1_36476831_-	intronic
CAediting_46758	chr1_36476832_-	intronic
CAediting_46759	chr1_36476833_-	intronic
CAediting_46760	chr1_36476839_-	intronic
CAediting_46761	chr1_36476840_-	intronic
CAediting_46762	chr1_36476843_-	intronic
CAediting_46763	chr1_36476845_-	intronic
CAediting_46764	chr1_36476863_-	intronic
CAediting_46765	chr1_36476869_-	intronic
CAediting_46766	chr1_36476873_-	intronic
CAediting_46767	chr1_36476888_-	intronic
CAediting_46768	chr1_36476889_-	intronic
CAediting_46769	chr1_36476913_-	intronic
CAediting_46770	chr1_36476916_-	intronic
CAediting_46771	chr1_36476919_-	intronic
CAediting_46772	chr1_36476920_-	intronic
CAediting_46773	chr1_36476926_-	intronic
CAediting_46774	chr1_36476943_-	intronic
CAediting_46775	chr1_36476949_-	intronic
CAediting_46776	chr1_36476959_-	intronic
CAediting_46777	chr1_36476961_-	intronic
CAediting_46778	chr1_36477294_-	ncRNA_exonic
CAediting_46779	chr1_36477331_-	ncRNA_exonic
CAediting_46780	chr1_36477335_-	ncRNA_exonic
CAediting_46781	chr1_36477355_-	ncRNA_exonic
CAediting_46782	chr1_36477356_-	ncRNA_exonic
CAediting_46783	chr1_36477397_-	ncRNA_exonic
CAediting_46784	chr1_36477423_-	ncRNA_exonic
CAediting_46785	chr1_36477426_-	ncRNA_exonic
CAediting_46786	chr1_36477427_-	ncRNA_exonic
CAediting_46787	chr1_36477428_-	ncRNA_exonic
CAediting_46788	chr1_36477478_-	ncRNA_exonic
CAediting_46789	chr1_36477480_-	ncRNA_exonic
CAediting_46790	chr1_36477549_-	ncRNA_exonic
CAediting_46791	chr1_36477568_-	ncRNA_exonic
CAediting_46792	chr1_36477571_-	ncRNA_exonic
CAediting_46793	chr1_36477797_-	ncRNA_intronic
CAediting_46794	chr1_36477811_-	ncRNA_intronic
CAediting_46795	chr1_36477816_-	ncRNA_intronic
CAediting_46796	chr1_36477821_-	ncRNA_intronic
CAediting_46797	chr1_36477826_-	ncRNA_intronic
CAediting_46798	chr1_36477831_-	ncRNA_intronic
CAediting_46799	chr1_36477832_-	ncRNA_intronic
CAediting_46800	chr1_36477848_-	ncRNA_intronic
CAediting_46801	chr1_36477851_-	ncRNA_intronic
CAediting_46802	chr1_36477856_-	ncRNA_intronic
CAediting_46803	chr1_36477870_-	ncRNA_intronic
CAediting_46804	chr1_36477874_-	ncRNA_intronic
CAediting_46805	chr1_36477887_-	ncRNA_intronic
CAediting_46806	chr1_36477891_-	ncRNA_intronic
CAediting_46807	chr1_36477897_-	ncRNA_intronic
CAediting_46808	chr1_36477923_-	ncRNA_intronic
CAediting_46809	chr1_36477927_-	ncRNA_intronic
CAediting_46810	chr1_36477933_-	ncRNA_intronic
CAediting_46811	chr1_36477953_-	ncRNA_intronic
CAediting_46812	chr1_36477954_-	ncRNA_intronic
CAediting_46813	chr1_36477959_-	ncRNA_intronic
CAediting_46814	chr1_36477961_-	ncRNA_intronic
CAediting_46815	chr1_36477992_-	ncRNA_intronic
CAediting_46816	chr1_36478022_-	ncRNA_intronic
CAediting_46817	chr1_36478025_-	ncRNA_intronic
CAediting_46818	chr1_36478030_-	ncRNA_intronic
CAediting_46819	chr1_36478031_-	ncRNA_intronic
CAediting_46820	chr1_36478266_-	ncRNA_intronic
CAediting_46821	chr1_36478270_-	ncRNA_intronic
CAediting_46822	chr1_36478272_-	ncRNA_intronic
CAediting_46823	chr1_36478284_-	ncRNA_intronic
CAediting_46824	chr1_36478285_-	ncRNA_intronic
CAediting_46825	chr1_36478286_-	ncRNA_intronic
CAediting_46826	chr1_36478346_-	ncRNA_intronic
CAediting_46827	chr1_36478407_-	ncRNA_intronic
CAediting_46828	chr1_36478417_-	ncRNA_intronic
CAediting_46829	chr1_36478472_-	ncRNA_intronic
CAediting_46830	chr1_36478477_-	ncRNA_intronic
CAediting_46831	chr1_36478493_-	ncRNA_intronic
CAediting_46832	chr1_36478496_-	ncRNA_intronic
CAediting_46833	chr1_36478497_-	ncRNA_intronic
CAediting_46834	chr1_36478527_-	ncRNA_intronic
CAediting_46835	chr1_36478588_-	ncRNA_intronic
CAediting_46836	chr1_36478589_-	ncRNA_intronic
CAediting_46837	chr1_36478591_-	ncRNA_intronic
CAediting_46838	chr1_36478600_-	ncRNA_intronic
CAediting_46839	chr1_36478603_-	ncRNA_intronic
CAediting_46840	chr1_36478604_-	ncRNA_intronic
CAediting_46841	chr1_36478605_-	ncRNA_intronic
CAediting_46842	chr1_36478643_-	ncRNA_intronic
CAediting_46843	chr1_36478645_-	ncRNA_intronic
CAediting_46844	chr1_36478674_-	ncRNA_intronic
CAediting_46845	chr1_36478682_-	ncRNA_intronic
CAediting_46846	chr1_36478719_-	ncRNA_intronic
CAediting_46847	chr1_36478721_-	ncRNA_intronic
CAediting_46848	chr1_36478724_-	ncRNA_intronic
CAediting_46849	chr1_36478739_-	ncRNA_intronic
CAediting_46850	chr1_36478769_-	ncRNA_intronic
CAediting_46851	chr1_36478782_-	ncRNA_intronic
CAediting_46852	chr1_36478783_-	ncRNA_intronic
CAediting_46853	chr1_36478789_-	ncRNA_intronic
CAediting_46854	chr1_36478794_-	ncRNA_intronic
CAediting_46855	chr1_36478799_-	ncRNA_intronic
CAediting_46856	chr1_36478804_-	ncRNA_intronic
CAediting_46857	chr1_36478805_-	ncRNA_intronic
CAediting_46858	chr1_36478845_-	ncRNA_intronic
CAediting_46859	chr1_36478847_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_46735	chr1_36468769_-	SINE	Alu	AluJb
CAediting_46736	chr1_36468827_-	SINE	Alu	AluJb
CAediting_46737	chr1_36468833_-	SINE	Alu	AluJb
CAediting_46738	chr1_36468834_-	SINE	Alu	AluJb
CAediting_46739	chr1_36468840_-	SINE	Alu	AluJb
CAediting_46740	chr1_36470287_-	SINE	Alu	AluSx1
CAediting_46741	chr1_36475011_-	SINE	Alu	AluSq
CAediting_46742	chr1_36475012_-	SINE	Alu	AluSq
CAediting_46743	chr1_36476670_-	SINE	Alu	AluJb
CAediting_46744	chr1_36476744_-	SINE	Alu	AluJb
CAediting_46745	chr1_36476745_-	SINE	Alu	AluJb
CAediting_46746	chr1_36476753_-	SINE	Alu	AluJb
CAediting_46747	chr1_36476758_-	SINE	Alu	AluJb
CAediting_46748	chr1_36476763_-	SINE	Alu	AluJb
CAediting_46749	chr1_36476768_-	SINE	Alu	AluJb
CAediting_46750	chr1_36476776_-	SINE	Alu	AluJb
CAediting_46751	chr1_36476785_-	SINE	Alu	AluJb
CAediting_46752	chr1_36476799_-	SINE	Alu	AluJb
CAediting_46753	chr1_36476821_-	SINE	Alu	AluJb
CAediting_46754	chr1_36476825_-	SINE	Alu	AluJb
CAediting_46755	chr1_36476829_-	SINE	Alu	AluJb
CAediting_46756	chr1_36476830_-	SINE	Alu	AluJb
CAediting_46757	chr1_36476831_-	SINE	Alu	AluJb
CAediting_46758	chr1_36476832_-	SINE	Alu	AluJb
CAediting_46759	chr1_36476833_-	SINE	Alu	AluJb
CAediting_46760	chr1_36476839_-	SINE	Alu	AluJb
CAediting_46761	chr1_36476840_-	SINE	Alu	AluJb
CAediting_46762	chr1_36476843_-	SINE	Alu	AluJb
CAediting_46763	chr1_36476845_-	SINE	Alu	AluJb
CAediting_46764	chr1_36476863_-	SINE	Alu	AluJb
CAediting_46765	chr1_36476869_-	SINE	Alu	AluJb
CAediting_46766	chr1_36476873_-	SINE	Alu	AluJb
CAediting_46767	chr1_36476888_-	SINE	Alu	AluJb
CAediting_46768	chr1_36476889_-	SINE	Alu	AluJb
CAediting_46769	chr1_36476913_-	SINE	Alu	AluJb
CAediting_46770	chr1_36476916_-	SINE	Alu	AluJb
CAediting_46771	chr1_36476919_-	SINE	Alu	AluJb
CAediting_46772	chr1_36476920_-	SINE	Alu	AluJb
CAediting_46773	chr1_36476926_-	SINE	Alu	AluJb
CAediting_46774	chr1_36476943_-	SINE	Alu	AluJb
CAediting_46775	chr1_36476949_-	SINE	Alu	AluJb
CAediting_46776	chr1_36476959_-	SINE	Alu	AluJb
CAediting_46777	chr1_36476961_-	SINE	Alu	AluJb
CAediting_46778	chr1_36477294_-	SINE	Alu	AluSx3
CAediting_46779	chr1_36477331_-	SINE	Alu	AluSx3
CAediting_46780	chr1_36477335_-	SINE	Alu	AluSx3
CAediting_46781	chr1_36477355_-	SINE	Alu	AluSx3
CAediting_46782	chr1_36477356_-	SINE	Alu	AluSx3
CAediting_46783	chr1_36477397_-	SINE	Alu	AluSx3
CAediting_46784	chr1_36477423_-	SINE	Alu	AluSx3
CAediting_46785	chr1_36477426_-	SINE	Alu	AluSx3
CAediting_46786	chr1_36477427_-	SINE	Alu	AluSx3
CAediting_46787	chr1_36477428_-	SINE	Alu	AluSx3
CAediting_46788	chr1_36477478_-	SINE	Alu	AluSx3
CAediting_46789	chr1_36477480_-	SINE	Alu	AluSx3
CAediting_46790	chr1_36477549_-	SINE	Alu	AluSx3
CAediting_46791	chr1_36477568_-	LINE	L2	L2c
CAediting_46792	chr1_36477571_-	LINE	L2	L2c
CAediting_46793	chr1_36477797_-	SINE	Alu	AluY
CAediting_46794	chr1_36477811_-	SINE	Alu	AluY
CAediting_46795	chr1_36477816_-	SINE	Alu	AluY
CAediting_46796	chr1_36477821_-	SINE	Alu	AluY
CAediting_46797	chr1_36477826_-	SINE	Alu	AluY
CAediting_46798	chr1_36477831_-	SINE	Alu	AluY
CAediting_46799	chr1_36477832_-	SINE	Alu	AluY
CAediting_46800	chr1_36477848_-	SINE	Alu	AluY
CAediting_46801	chr1_36477851_-	SINE	Alu	AluY
CAediting_46802	chr1_36477856_-	SINE	Alu	AluY
CAediting_46803	chr1_36477870_-	SINE	Alu	AluY
CAediting_46804	chr1_36477874_-	SINE	Alu	AluY
CAediting_46805	chr1_36477887_-	SINE	Alu	AluY
CAediting_46806	chr1_36477891_-	SINE	Alu	AluY
CAediting_46807	chr1_36477897_-	SINE	Alu	AluY
CAediting_46808	chr1_36477923_-	SINE	Alu	AluY
CAediting_46809	chr1_36477927_-	SINE	Alu	AluY
CAediting_46810	chr1_36477933_-	SINE	Alu	AluY
CAediting_46811	chr1_36477953_-	SINE	Alu	AluY
CAediting_46812	chr1_36477954_-	SINE	Alu	AluY
CAediting_46813	chr1_36477959_-	SINE	Alu	AluY
CAediting_46814	chr1_36477961_-	SINE	Alu	AluY
CAediting_46815	chr1_36477992_-	SINE	Alu	AluY
CAediting_46816	chr1_36478022_-	SINE	Alu	AluY
CAediting_46817	chr1_36478025_-	SINE	Alu	AluY
CAediting_46818	chr1_36478030_-	SINE	Alu	AluY
CAediting_46819	chr1_36478031_-	SINE	Alu	AluY
CAediting_46820	chr1_36478266_-	SINE	Alu	AluSx1
CAediting_46821	chr1_36478270_-	SINE	Alu	AluSx1
CAediting_46822	chr1_36478272_-	SINE	Alu	AluSx1
CAediting_46823	chr1_36478284_-	SINE	Alu	AluSx1
CAediting_46824	chr1_36478285_-	SINE	Alu	AluSx1
CAediting_46825	chr1_36478286_-	SINE	Alu	AluSx1
CAediting_46826	chr1_36478346_-	SINE	Alu	AluSx1
CAediting_46827	chr1_36478407_-	SINE	Alu	AluSx1
CAediting_46828	chr1_36478417_-	SINE	Alu	AluSx1
CAediting_46829	chr1_36478472_-	SINE	Alu	AluSx1
CAediting_46830	chr1_36478477_-	SINE	Alu	AluSx1
CAediting_46831	chr1_36478493_-	SINE	Alu	AluSx1
CAediting_46832	chr1_36478496_-	SINE	Alu	AluSx1
CAediting_46833	chr1_36478497_-	SINE	Alu	AluSx1
CAediting_46834	chr1_36478527_-	SINE	Alu	AluSx1
CAediting_46835	chr1_36478588_-	SINE	Alu	AluJb
CAediting_46836	chr1_36478589_-	SINE	Alu	AluJb
CAediting_46837	chr1_36478591_-	SINE	Alu	AluJb
CAediting_46838	chr1_36478600_-	SINE	Alu	AluJb
CAediting_46839	chr1_36478603_-	SINE	Alu	AluJb
CAediting_46840	chr1_36478604_-	SINE	Alu	AluJb
CAediting_46841	chr1_36478605_-	SINE	Alu	AluJb
CAediting_46842	chr1_36478643_-	SINE	Alu	AluJb
CAediting_46843	chr1_36478645_-	SINE	Alu	AluJb
CAediting_46844	chr1_36478674_-	SINE	Alu	AluJb
CAediting_46845	chr1_36478682_-	SINE	Alu	AluJb
CAediting_46846	chr1_36478719_-	SINE	Alu	AluJb
CAediting_46847	chr1_36478721_-	SINE	Alu	AluJb
CAediting_46848	chr1_36478724_-	SINE	Alu	AluJb
CAediting_46849	chr1_36478739_-	SINE	Alu	AluJb
CAediting_46850	chr1_36478769_-	SINE	Alu	AluJb
CAediting_46851	chr1_36478782_-	SINE	Alu	AluJb
CAediting_46852	chr1_36478783_-	SINE	Alu	AluJb
CAediting_46853	chr1_36478789_-	SINE	Alu	AluJb
CAediting_46854	chr1_36478794_-	SINE	Alu	AluJb
CAediting_46855	chr1_36478799_-	SINE	Alu	AluJb
CAediting_46856	chr1_36478804_-	SINE	Alu	AluJb
CAediting_46857	chr1_36478805_-	SINE	Alu	AluJb
CAediting_46858	chr1_36478845_-	SINE	Alu	AluJb
CAediting_46859	chr1_36478847_-	SINE	Alu	AluJb

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RNA A-to-I editing events in the alternative splicing sites for CSF3R

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000119535.16.CSF3R.

Correlation between RNA A-to-I editing and PSI for ENSG00000119535.16.CSF3R.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CSF3R

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for CSF3R

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for CSF3R

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_468389	chr6_31355314_-	ENSG00000119535.16	ENST00000373106	hsa-miR-6891-5p	36466214	36466219	6mer	36466213	36466230	147	-23.78
CAediting_468389	chr6_31355314_-	ENSG00000119535.16	ENST00000373103	hsa-miR-6891-5p	36466214	36466219	6mer	36466213	36466230	147	-23.78
CAediting_468389	chr6_31355314_-	ENSG00000119535.16	ENST00000361632	hsa-miR-6891-5p	36466214	36466219	6mer	36466213	36466230	147	-23.78
CAediting_468389	chr6_31355314_-	ENSG00000119535.16	ENST00000464465	hsa-miR-6891-5p	36466214	36466219	6mer	36466213	36466230	147	-23.78

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CSF3R

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000464365.2	retained_intron
ENST00000480825.5	retained_intron
ENST00000526980.4	processed_transcript

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_46735	ENST00000464365.2	chr1_36468769_-	-662.50	-659.90	-668.70
CAediting_46736	ENST00000464365.2	chr1_36468827_-	-661.80	-659.90	-668.70
CAediting_46737	ENST00000464365.2	chr1_36468833_-	-660.00	-659.90	-668.70
CAediting_46738	ENST00000464365.2	chr1_36468834_-	-660.00	-659.90	-668.70
CAediting_46739	ENST00000464365.2	chr1_36468840_-	-663.60	-659.90	-668.70
CAediting_46735	ENST00000480825.5	chr1_36468769_-	-2299.10	-2299.00	-2305.60
CAediting_46736	ENST00000480825.5	chr1_36468827_-	-2300.90	-2299.00	-2305.60
CAediting_46737	ENST00000480825.5	chr1_36468833_-	-2300.54	-2299.00	-2305.60
CAediting_46738	ENST00000480825.5	chr1_36468834_-	-2300.54	-2299.00	-2305.60
CAediting_46739	ENST00000480825.5	chr1_36468840_-	-2298.80	-2299.00	-2305.60
CAediting_46778	ENST00000526980.4	chr1_36477294_-	-307.30	-307.30	-326.90
CAediting_46779	ENST00000526980.4	chr1_36477331_-	-308.60	-307.30	-326.90
CAediting_46780	ENST00000526980.4	chr1_36477335_-	-307.70	-307.30	-326.90
CAediting_46781	ENST00000526980.4	chr1_36477355_-	-307.60	-307.30	-326.90
CAediting_46782	ENST00000526980.4	chr1_36477356_-	-307.30	-307.30	-326.90
CAediting_46783	ENST00000526980.4	chr1_36477397_-	-308.70	-307.30	-326.90
CAediting_46784	ENST00000526980.4	chr1_36477423_-	-309.60	-307.30	-326.90
CAediting_46785	ENST00000526980.4	chr1_36477426_-	-307.30	-307.30	-326.90
CAediting_46786	ENST00000526980.4	chr1_36477427_-	-307.30	-307.30	-326.90
CAediting_46787	ENST00000526980.4	chr1_36477428_-	-307.30	-307.30	-326.90
CAediting_46788	ENST00000526980.4	chr1_36477478_-	-309.10	-307.30	-326.90
CAediting_46789	ENST00000526980.4	chr1_36477480_-	-313.20	-307.30	-326.90
CAediting_46790	ENST00000526980.4	chr1_36477549_-	-308.50	-307.30	-326.90
CAediting_46791	ENST00000526980.4	chr1_36477568_-	-307.30	-307.30	-326.90
CAediting_46792	ENST00000526980.4	chr1_36477571_-	-307.50	-307.30	-326.90

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Relation with ADAR for CSF3R

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LAML	CAediting_46858	chr1_36478845_-	0.00694931187607242	0.22100153362593	.	.	.	.

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Relation with cancer stages for CSF3R

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for CSF3R

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
LAML	CAediting_46818	chr1_36478030_-	0.0196864503894143	0.0114573	1539

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RelatedDrugs for CSF3R

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
CSF3R	Q99062	DB00019	Pegfilgrastim	Granulocyte colony-stimulating factor receptor	BiotechDrug	approved
CSF3R	Q99062	DB00099	Filgrastim	Granulocyte colony-stimulating factor receptor	BiotechDrug	approved
CSF3R	Q99062	DB13144	Lenograstim	Granulocyte colony-stimulating factor receptor	BiotechDrug	approved\|investigational
CSF3R	Q99062	DB13200	Lipegfilgrastim	Granulocyte colony-stimulating factor receptor	BiotechDrug	approved\|investigational

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RelatedDiseases for CSF3R

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
CSF3R	C4310764	NEUTROPENIA, SEVERE CONGENITAL, 7, AUTOSOMAL RECESSIVE	3	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
CSF3R	C0340970	Congenital neutropenia	2	GENOMICS_ENGLAND
CSF3R	C0023481	Chronic Neutrophilic Leukemia	1	CGI;ORPHANET
CSF3R	C0023518	Leukocytosis	1	CTD_human
CSF3R	C0151857	Pleocytosis	1	CTD_human
CSF3R	C0543669	Neutrophilia, Hereditary	1	ORPHANET;UNIPROT
CSF3R	C1292772	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	1	CGI;ORPHANET

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene