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Editing gene: ATF2 (CAeditome ID:1386)

Gene summary for ATF2

Gene summary

Gene information	Gene symbol	ATF2
	Gene ID	1386
	Gene name	activating transcription factor 2
	Synonyms	CRE-BP1\|CREB-2\|CREB2\|HB16\|TREB7
	Cytomap	2q31.1
	Type of gene	protein-coding
	Description	cyclic AMP-dependent transcription factor ATF-2activating transcription factor 2 splice variant ATF2-var2cAMP response element-binding protein CRE-BP1cAMP responsive element binding protein 2, formerlycAMP-dependent transcription factor ATF-2cyclic A
	Modification date	20210531
	UniProtAcc	P15336
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
ATF2	GO:0000978	Cyclic AMP-dependent transcription factor ATF-2	19861239
ATF2	GO:0000987	Cyclic AMP-dependent transcription factor ATF-2	2196176
ATF2	GO:0001228	Cyclic AMP-dependent transcription factor ATF-2	16300731
ATF2	GO:0001228	Cyclic AMP-dependent transcription factor ATF-2	18671972
ATF2	GO:0001228	Cyclic AMP-dependent transcription factor ATF-2	19861239
ATF2	GO:0003700	Cyclic AMP-dependent transcription factor ATF-2	8798441
ATF2	GO:0008140	Cyclic AMP-dependent transcription factor ATF-2	19861239
ATF2	GO:0010485	Cyclic AMP-dependent transcription factor ATF-2	10821277
ATF2	GO:0035497	Cyclic AMP-dependent transcription factor ATF-2	19861239
ATF2	GO:0035497	Cyclic AMP-dependent transcription factor ATF-2	23729669
ATF2	GO:0044013	Cyclic AMP-dependent transcription factor ATF-2	10821277
ATF2	GO:1990837	Cyclic AMP-dependent transcription factor ATF-2	28473536
ATF2	GO:0006357	Cyclic AMP-dependent transcription factor ATF-2	19861239
ATF2	GO:0006970	Cyclic AMP-dependent transcription factor ATF-2	21098032
ATF2	GO:0006974	Cyclic AMP-dependent transcription factor ATF-2	22304920
ATF2	GO:0043967	Cyclic AMP-dependent transcription factor ATF-2	10821277
ATF2	GO:0043969	Cyclic AMP-dependent transcription factor ATF-2	10821277
ATF2	GO:0045944	Cyclic AMP-dependent transcription factor ATF-2	16300731
ATF2	GO:0045944	Cyclic AMP-dependent transcription factor ATF-2	18671972
ATF2	GO:0110024	Cyclic AMP-dependent transcription factor ATF-2	22982025
ATF2	GO:0005634	Cyclic AMP-dependent transcription factor ATF-2	18397884
ATF2	GO:0005634	Cyclic AMP-dependent transcription factor ATF-2	19861239
ATF2	GO:0005634	Cyclic AMP-dependent transcription factor ATF-2	21098032
ATF2	GO:0005634	Cyclic AMP-dependent transcription factor ATF-2	22304920
ATF2	GO:0005634	Cyclic AMP-dependent transcription factor ATF-2	8798441
ATF2	GO:0005654	Cyclic AMP-dependent transcription factor ATF-2	0000052
ATF2	GO:0005737	Cyclic AMP-dependent transcription factor ATF-2	22304920
ATF2	GO:0005741	Cyclic AMP-dependent transcription factor ATF-2	22304920
ATF2	GO:0035861	Cyclic AMP-dependent transcription factor ATF-2	15916964
ATF2	GO:0000785	Cyclic AMP-dependent transcription factor ATF-2	23729669
ATF2	GO:1902562	Cyclic AMP-dependent transcription factor ATF-2	10821277

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RNA A-to-I events for ATF2

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000115966.15

RNA A-to-I editing events in Cancer.

CAediting_226450(175081913, -), CAediting_226451(175082012, -), CAediting_226452(175082014, -), CAediting_226453(175085290, -), CAediting_226454(175085292, -), CAediting_226455(175085313, -), CAediting_226456(175085317, -), CAediting_226457(175085318, -), CAediting_226458(175085330, -), CAediting_226459(175085331, -), CAediting_226460(175085332, -), CAediting_226461(175085343, -), CAediting_226462(175085363, -), CAediting_226463(175085369, -), CAediting_226464(175085426, -), CAediting_226465(175085435, -), CAediting_226466(175085505, -), CAediting_226467(175086627, -), CAediting_226468(175086628, -), CAediting_226469(175086641, -), CAediting_226470(175086655, -), CAediting_226471(175086681, -), CAediting_226472(175086682, -), CAediting_226473(175088579, -), CAediting_226474(175088580, -), CAediting_226475(175088581, -), CAediting_226476(175088582, -), CAediting_226477(175088583, -), CAediting_226478(175088589, -), CAediting_226479(175088649, -), CAediting_226480(175089094, -), CAediting_226481(175094828, -), CAediting_226482(175095160, -), CAediting_226483(175095165, -), CAediting_226484(175095180, -), CAediting_226485(175095190, -), CAediting_226486(175095194, -), CAediting_226487(175095195, -), CAediting_226488(175095210, -), CAediting_226489(175095213, -), CAediting_226490(175095226, -), CAediting_226491(175095230, -), CAediting_226492(175095236, -), CAediting_226493(175095242, -), CAediting_226494(175095267, -), CAediting_226495(175099200, -), CAediting_226496(175099201, -), CAediting_226497(175099220, -), CAediting_226498(175099228, -), CAediting_226499(175099241, -), CAediting_226500(175099398, -), CAediting_226501(175106405, -), CAediting_226502(175106415, -), CAediting_226503(175106591, -), CAediting_226504(175106592, -), CAediting_226505(175106784, -), CAediting_226506(175107025, -), CAediting_226507(175107068, -), CAediting_226508(175107081, -), CAediting_226509(175110886, -), CAediting_226510(175140811, -), CAediting_226511(175141589, -), CAediting_226512(175141590, -), CAediting_226513(175141604, -), CAediting_226514(175141621, -), CAediting_226515(175141625, -), CAediting_226516(175141631, -), CAediting_226517(175141703, -), CAediting_226518(175141765, -), CAediting_226519(175142306, -), CAediting_226520(175158283, -), CAediting_226521(175158309, -), CAediting_226522(175158318, -), CAediting_226523(175158323, -), CAediting_226524(175158328, -), CAediting_226525(175158334, -), CAediting_226526(175158350, -), CAediting_226527(175158354, -), CAediting_226528(175158370, -), CAediting_226529(175158397, -), CAediting_226530(175158440, -), CAediting_226531(175158441, -), CAediting_226532(175158732, -), CAediting_226533(175160916, -), CAediting_226534(175160943, -), CAediting_226535(175160981, -), CAediting_226536(175161036, -), CAediting_226537(175165109, -), CAediting_226538(175165807, -),

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RNA editing positional annotations for ATF2 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_226450	chr2_175081913_-	ncRNA_intronic
CAediting_226451	chr2_175082012_-	ncRNA_intronic
CAediting_226452	chr2_175082014_-	ncRNA_intronic
CAediting_226453	chr2_175085290_-	ncRNA_intronic
CAediting_226454	chr2_175085292_-	ncRNA_intronic
CAediting_226455	chr2_175085313_-	ncRNA_intronic
CAediting_226456	chr2_175085317_-	ncRNA_intronic
CAediting_226457	chr2_175085318_-	ncRNA_intronic
CAediting_226458	chr2_175085330_-	ncRNA_intronic
CAediting_226459	chr2_175085331_-	ncRNA_intronic
CAediting_226460	chr2_175085332_-	ncRNA_intronic
CAediting_226461	chr2_175085343_-	ncRNA_intronic
CAediting_226462	chr2_175085363_-	ncRNA_intronic
CAediting_226463	chr2_175085369_-	ncRNA_intronic
CAediting_226464	chr2_175085426_-	ncRNA_intronic
CAediting_226465	chr2_175085435_-	ncRNA_intronic
CAediting_226466	chr2_175085505_-	ncRNA_intronic
CAediting_226467	chr2_175086627_-	ncRNA_intronic
CAediting_226468	chr2_175086628_-	ncRNA_intronic
CAediting_226469	chr2_175086641_-	ncRNA_intronic
CAediting_226470	chr2_175086655_-	ncRNA_intronic
CAediting_226471	chr2_175086681_-	ncRNA_intronic
CAediting_226472	chr2_175086682_-	ncRNA_intronic
CAediting_226473	chr2_175088579_-	ncRNA_intronic
CAediting_226474	chr2_175088580_-	ncRNA_intronic
CAediting_226475	chr2_175088581_-	ncRNA_intronic
CAediting_226476	chr2_175088582_-	ncRNA_intronic
CAediting_226477	chr2_175088583_-	ncRNA_intronic
CAediting_226478	chr2_175088589_-	ncRNA_intronic
CAediting_226479	chr2_175088649_-	ncRNA_intronic
CAediting_226480	chr2_175089094_-	ncRNA_intronic
CAediting_226481	chr2_175094828_-	intronic
CAediting_226482	chr2_175095160_-	intronic
CAediting_226483	chr2_175095165_-	intronic
CAediting_226484	chr2_175095180_-	intronic
CAediting_226485	chr2_175095190_-	intronic
CAediting_226486	chr2_175095194_-	intronic
CAediting_226487	chr2_175095195_-	intronic
CAediting_226488	chr2_175095210_-	intronic
CAediting_226489	chr2_175095213_-	intronic
CAediting_226490	chr2_175095226_-	intronic
CAediting_226491	chr2_175095230_-	intronic
CAediting_226492	chr2_175095236_-	intronic
CAediting_226493	chr2_175095242_-	intronic
CAediting_226494	chr2_175095267_-	intronic
CAediting_226495	chr2_175099200_-	intronic
CAediting_226496	chr2_175099201_-	intronic
CAediting_226497	chr2_175099220_-	intronic
CAediting_226498	chr2_175099228_-	intronic
CAediting_226499	chr2_175099241_-	intronic
CAediting_226500	chr2_175099398_-	intronic
CAediting_226501	chr2_175106405_-	intronic
CAediting_226502	chr2_175106415_-	intronic
CAediting_226503	chr2_175106591_-	intronic
CAediting_226504	chr2_175106592_-	intronic
CAediting_226505	chr2_175106784_-	intronic
CAediting_226506	chr2_175107025_-	intronic
CAediting_226507	chr2_175107068_-	intronic
CAediting_226508	chr2_175107081_-	intronic
CAediting_226509	chr2_175110886_-	intronic
CAediting_226510	chr2_175140811_-	ncRNA_intronic
CAediting_226511	chr2_175141589_-	ncRNA_intronic
CAediting_226512	chr2_175141590_-	ncRNA_intronic
CAediting_226513	chr2_175141604_-	ncRNA_intronic
CAediting_226514	chr2_175141621_-	ncRNA_intronic
CAediting_226515	chr2_175141625_-	ncRNA_intronic
CAediting_226516	chr2_175141631_-	ncRNA_intronic
CAediting_226517	chr2_175141703_-	ncRNA_intronic
CAediting_226518	chr2_175141765_-	ncRNA_intronic
CAediting_226519	chr2_175142306_-	ncRNA_intronic
CAediting_226520	chr2_175158283_-	ncRNA_intronic
CAediting_226521	chr2_175158309_-	ncRNA_intronic
CAediting_226522	chr2_175158318_-	ncRNA_intronic
CAediting_226523	chr2_175158323_-	ncRNA_intronic
CAediting_226524	chr2_175158328_-	ncRNA_intronic
CAediting_226525	chr2_175158334_-	ncRNA_intronic
CAediting_226526	chr2_175158350_-	ncRNA_intronic
CAediting_226527	chr2_175158354_-	ncRNA_intronic
CAediting_226528	chr2_175158370_-	ncRNA_intronic
CAediting_226529	chr2_175158397_-	ncRNA_intronic
CAediting_226530	chr2_175158440_-	ncRNA_intronic
CAediting_226531	chr2_175158441_-	ncRNA_intronic
CAediting_226532	chr2_175158732_-	ncRNA_intronic
CAediting_226533	chr2_175160916_-	ncRNA_intronic
CAediting_226534	chr2_175160943_-	ncRNA_intronic
CAediting_226535	chr2_175160981_-	ncRNA_intronic
CAediting_226536	chr2_175161036_-	ncRNA_intronic
CAediting_226537	chr2_175165109_-	ncRNA_intronic
CAediting_226538	chr2_175165807_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_226450	chr2_175081913_-	SINE	Alu	AluSx1
CAediting_226451	chr2_175082012_-	SINE	Alu	AluSx1
CAediting_226452	chr2_175082014_-	SINE	Alu	AluSx1
CAediting_226453	chr2_175085290_-	SINE	Alu	AluSz
CAediting_226454	chr2_175085292_-	SINE	Alu	AluSz
CAediting_226455	chr2_175085313_-	SINE	Alu	AluSz
CAediting_226456	chr2_175085317_-	SINE	Alu	AluSz
CAediting_226457	chr2_175085318_-	SINE	Alu	AluSz
CAediting_226458	chr2_175085330_-	SINE	Alu	AluSz
CAediting_226459	chr2_175085331_-	SINE	Alu	AluSz
CAediting_226460	chr2_175085332_-	SINE	Alu	AluSz
CAediting_226461	chr2_175085343_-	SINE	Alu	AluSz
CAediting_226462	chr2_175085363_-	SINE	Alu	AluSz
CAediting_226463	chr2_175085369_-	SINE	Alu	AluSz
CAediting_226464	chr2_175085426_-	SINE	Alu	AluSz
CAediting_226465	chr2_175085435_-	SINE	Alu	AluSz
CAediting_226466	chr2_175085505_-	SINE	Alu	AluSz
CAediting_226467	chr2_175086627_-	SINE	Alu	AluSz
CAediting_226468	chr2_175086628_-	SINE	Alu	AluSz
CAediting_226469	chr2_175086641_-	SINE	Alu	AluSz
CAediting_226470	chr2_175086655_-	SINE	Alu	AluSz
CAediting_226471	chr2_175086681_-	SINE	Alu	AluSz
CAediting_226472	chr2_175086682_-	SINE	Alu	AluSz
CAediting_226473	chr2_175088579_-	DNA	TcMar-Mariner	MADE1
CAediting_226474	chr2_175088580_-	DNA	TcMar-Mariner	MADE1
CAediting_226475	chr2_175088581_-	DNA	TcMar-Mariner	MADE1
CAediting_226476	chr2_175088582_-	DNA	TcMar-Mariner	MADE1
CAediting_226477	chr2_175088583_-	DNA	TcMar-Mariner	MADE1
CAediting_226478	chr2_175088589_-	DNA	TcMar-Mariner	MADE1
CAediting_226479	chr2_175088649_-	DNA	TcMar-Mariner	MADE1
CAediting_226480	chr2_175089094_-	SINE	Alu	AluSp
CAediting_226481	chr2_175094828_-	SINE	Alu	AluJb
CAediting_226482	chr2_175095160_-	SINE	Alu	AluSx1
CAediting_226483	chr2_175095165_-	SINE	Alu	AluSx1
CAediting_226484	chr2_175095180_-	SINE	Alu	AluSx1
CAediting_226485	chr2_175095190_-	SINE	Alu	AluSx1
CAediting_226486	chr2_175095194_-	SINE	Alu	AluSx1
CAediting_226487	chr2_175095195_-	SINE	Alu	AluSx1
CAediting_226488	chr2_175095210_-	SINE	Alu	AluSx1
CAediting_226489	chr2_175095213_-	SINE	Alu	AluSx1
CAediting_226490	chr2_175095226_-	SINE	Alu	AluSx1
CAediting_226491	chr2_175095230_-	SINE	Alu	AluSx1
CAediting_226492	chr2_175095236_-	SINE	Alu	AluSx1
CAediting_226493	chr2_175095242_-	SINE	Alu	AluSx1
CAediting_226494	chr2_175095267_-	SINE	Alu	AluSx1
CAediting_226495	chr2_175099200_-	SINE	Alu	AluSz
CAediting_226496	chr2_175099201_-	SINE	Alu	AluSz
CAediting_226497	chr2_175099220_-	SINE	Alu	AluSz
CAediting_226498	chr2_175099228_-	SINE	Alu	AluSz
CAediting_226499	chr2_175099241_-	SINE	Alu	AluSz
CAediting_226500	chr2_175099398_-	SINE	Alu	AluSz
CAediting_226501	chr2_175106405_-	SINE	Alu	AluSx1
CAediting_226502	chr2_175106415_-	SINE	Alu	AluSx1
CAediting_226503	chr2_175106591_-	SINE	Alu	AluSx1
CAediting_226504	chr2_175106592_-	SINE	Alu	AluSx1
CAediting_226505	chr2_175106784_-	SINE	Alu	AluSx1
CAediting_226506	chr2_175107025_-	SINE	Alu	AluJo
CAediting_226507	chr2_175107068_-	SINE	Alu	AluJo
CAediting_226508	chr2_175107081_-	SINE	Alu	AluJo
CAediting_226509	chr2_175110886_-	SINE	Alu	AluSx
CAediting_226510	chr2_175140811_-	SINE	Alu	AluJr
CAediting_226511	chr2_175141589_-	SINE	Alu	AluY
CAediting_226512	chr2_175141590_-	SINE	Alu	AluY
CAediting_226513	chr2_175141604_-	SINE	Alu	AluY
CAediting_226514	chr2_175141621_-	SINE	Alu	AluY
CAediting_226515	chr2_175141625_-	SINE	Alu	AluY
CAediting_226516	chr2_175141631_-	SINE	Alu	AluY
CAediting_226517	chr2_175141703_-	SINE	Alu	AluY
CAediting_226518	chr2_175141765_-	SINE	Alu	AluY
CAediting_226519	chr2_175142306_-	SINE	Alu	AluSq2
CAediting_226520	chr2_175158283_-	SINE	Alu	AluJb
CAediting_226521	chr2_175158309_-	SINE	Alu	AluJb
CAediting_226522	chr2_175158318_-	SINE	Alu	AluJb
CAediting_226523	chr2_175158323_-	SINE	Alu	AluJb
CAediting_226524	chr2_175158328_-	SINE	Alu	AluJb
CAediting_226525	chr2_175158334_-	SINE	Alu	AluJb
CAediting_226526	chr2_175158350_-	SINE	Alu	AluJb
CAediting_226527	chr2_175158354_-	SINE	Alu	AluJb
CAediting_226528	chr2_175158370_-	SINE	Alu	AluJb
CAediting_226529	chr2_175158397_-	SINE	Alu	AluJb
CAediting_226530	chr2_175158440_-	SINE	Alu	AluJb
CAediting_226531	chr2_175158441_-	SINE	Alu	AluJb
CAediting_226532	chr2_175158732_-	SINE	Alu	AluJb
CAediting_226533	chr2_175160916_-	SINE	Alu	AluJb
CAediting_226534	chr2_175160943_-	SINE	Alu	AluJb
CAediting_226535	chr2_175160981_-	SINE	Alu	AluJb
CAediting_226536	chr2_175161036_-	SINE	Alu	AluJb
CAediting_226537	chr2_175165109_-	SINE	Alu	AluSx1
CAediting_226538	chr2_175165807_-	SINE	Alu	AluSc8

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RNA A-to-I editing events in the alternative splicing sites for ATF2

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000115966.15.ATF2.

Correlation between RNA A-to-I editing and PSI for ENSG00000115966.15.ATF2.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ATF2

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for ATF2

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for ATF2

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_393	chr1_1167164_+	ENSG00000115966.15	ENST00000345739	hsa-miR-200b-3p	175073921	175073927	7mer-m8	175073920	175073941	140	-8.97
CAediting_393	chr1_1167164_+	ENSG00000115966.15	ENST00000426833	hsa-miR-200b-3p	175073921	175073927	7mer-m8	175073920	175073941	140	-8.97
CAediting_393	chr1_1167164_+	ENSG00000115966.15	ENST00000409437	hsa-miR-200b-3p	175073921	175073927	7mer-m8	175073920	175073941	140	-8.97
CAediting_1399425	chr20_1392958_-	ENSG00000115966.15	ENST00000345739	hsa-miR-6869-5p	175073109	175073115	7mer-m8	175073108	175073128	149	-19.09
CAediting_1399425	chr20_1392958_-	ENSG00000115966.15	ENST00000426833	hsa-miR-6869-5p	175073109	175073115	7mer-m8	175073108	175073128	149	-19.09
CAediting_1399425	chr20_1392958_-	ENSG00000115966.15	ENST00000409437	hsa-miR-6869-5p	175073109	175073115	7mer-m8	175073108	175073128	149	-19.09
CAediting_86358	chr1_109598906_+	ENSG00000115966.15	ENST00000417080	hsa-miR-197-5p	175074837	175074844	8mer-1a	175074837	175074859	152	-20.27
CAediting_396018	chr5_1062918_-	ENSG00000115966.15	ENST00000456655	hsa-miR-4635	175114732	175114738	7mer-m8	175114731	175114751	145	-13.41
CAediting_604450	chr7_133034877_-	ENSG00000115966.15	ENST00000456655	hsa-miR-3654	175114815	175114822	8mer-1a	175114815	175114833	149	-17.51
CAediting_396018	chr5_1062918_-	ENSG00000115966.15	ENST00000415955	hsa-miR-4635	175114732	175114738	7mer-m8	175114731	175114751	145	-13.41
CAediting_604450	chr7_133034877_-	ENSG00000115966.15	ENST00000415955	hsa-miR-3654	175114815	175114822	8mer-1a	175114815	175114833	149	-17.51
CAediting_396018	chr5_1062918_-	ENSG00000115966.15	ENST00000435231	hsa-miR-4635	175114732	175114738	7mer-m8	175114731	175114751	145	-13.41
CAediting_604450	chr7_133034877_-	ENSG00000115966.15	ENST00000435231	hsa-miR-3654	175114815	175114822	8mer-1a	175114815	175114833	149	-17.51

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_414656	chr5_72878640_+	ENSG00000115966.15	ENST00000345739	hsa-miR-4804-3p	175073998	175074004	7mer-m8	175073997	175074017	144	-10.83
CAediting_228905	chr2_188297554_+	ENSG00000115966.15	ENST00000345739	hsa-miR-561-3p	175073134	175073140	7mer-m8	175073133	175073154	140	-8.21
CAediting_228905	chr2_188297554_+	ENSG00000115966.15	ENST00000345739	hsa-miR-561-3p	175072466	175072472	7mer-m8	175072465	175072487	149	-10.95
CAediting_414656	chr5_72878640_+	ENSG00000115966.15	ENST00000426833	hsa-miR-4804-3p	175073998	175074004	7mer-m8	175073997	175074017	144	-10.83
CAediting_228905	chr2_188297554_+	ENSG00000115966.15	ENST00000426833	hsa-miR-561-3p	175073134	175073140	7mer-m8	175073133	175073154	140	-8.21
CAediting_228905	chr2_188297554_+	ENSG00000115966.15	ENST00000426833	hsa-miR-561-3p	175072466	175072472	7mer-m8	175072465	175072487	149	-10.95
CAediting_414656	chr5_72878640_+	ENSG00000115966.15	ENST00000409437	hsa-miR-4804-3p	175073998	175074004	7mer-m8	175073997	175074017	144	-10.83
CAediting_228905	chr2_188297554_+	ENSG00000115966.15	ENST00000409437	hsa-miR-561-3p	175073134	175073140	7mer-m8	175073133	175073154	140	-8.21
CAediting_228905	chr2_188297554_+	ENSG00000115966.15	ENST00000409437	hsa-miR-561-3p	175072466	175072472	7mer-m8	175072465	175072487	149	-10.95

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ATF2

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for ATF2

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
STAD	CAediting_226483	chr2_175095165_-	0.0228996407165633	0.298390367833061	.	.	.	.

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Relation with cancer stages for ATF2

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for ATF2

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for ATF2

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
ATF2	P15336	DB00852	Pseudoephedrine	Cyclic AMP-dependent transcription factor ATF-2	SmallMoleculeDrug	approved

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RelatedDiseases for ATF2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
ATF2	C0006826	Malignant Neoplasms	1	CTD_human
ATF2	C0027651	Neoplasms	1	CTD_human
ATF2	C0086692	Benign Neoplasm	1	CTD_human
ATF2	C0235874	Disease Exacerbation	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene