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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: DNAJC21 (CAeditome ID:134218)

Gene summary for DNAJC21

check button Gene summary
Gene informationGene symbol

DNAJC21

Gene ID

134218

Gene nameDnaJ heat shock protein family (Hsp40) member C21
SynonymsBMFS3|DNAJA5|GS3|JJJ1
Cytomap

5p13.2

Type of geneprotein-coding
DescriptiondnaJ homolog subfamily C member 21DnaJ (Hsp40) homolog, subfamily C, member 21DnaJ homology subfamily A member 5JJJ1 DnaJ domain protein homologdnaJ homolog subfamily A member 5
Modification date20210518
UniProtAcc

Q5F1R6

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
DNAJC21

GO:0005730

DnaJ homolog subfamily C member 21

0000052

DNAJC21

GO:0005829

DnaJ homolog subfamily C member 21

0000052


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RNA A-to-I events for DNAJC21

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000168724.13
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_401810(34932235, +), CAediting_401811(34933459, +), CAediting_401812(34933460, +), CAediting_401813(34937981, +), CAediting_401814(34941261, +), CAediting_401815(34941331, +), CAediting_401816(34943018, +), CAediting_401817(34945097, +), CAediting_401818(34945195, +), CAediting_401819(34945204, +), CAediting_401820(34945278, +), CAediting_401821(34945330, +), CAediting_401822(34950669, +), CAediting_401823(34950984, +), CAediting_401824(34951628, +), CAediting_401825(34951645, +), CAediting_401826(34951673, +), CAediting_401827(34951708, +), CAediting_401828(34951726, +), CAediting_401829(34951733, +), CAediting_401830(34951735, +), CAediting_401831(34951748, +), CAediting_401832(34951755, +), CAediting_401833(34951763, +), CAediting_401834(34951781, +), CAediting_401835(34951785, +), CAediting_401836(34951786, +), CAediting_401837(34952858, +), CAediting_401838(34952873, +), CAediting_401839(34952877, +), CAediting_401840(34952887, +), CAediting_401841(34952895, +), CAediting_401842(34952912, +), CAediting_401843(34952931, +), CAediting_401844(34952934, +), CAediting_401845(34952939, +), CAediting_401846(34952950, +), CAediting_401847(34952970, +), CAediting_401848(34952971, +), CAediting_401849(34952984, +), CAediting_401850(34952988, +), CAediting_401851(34952989, +), CAediting_401852(34952990, +), CAediting_401853(34952991, +), CAediting_401854(34952992, +), CAediting_401855(34952994, +), CAediting_401856(34952997, +), CAediting_401857(34952998, +), CAediting_401858(34953000, +), CAediting_401859(34953003, +), CAediting_401860(34953008, +), CAediting_401861(34953019, +), CAediting_401862(34953029, +), CAediting_401863(34953030, +), CAediting_401864(34953035, +), CAediting_401865(34953046, +), CAediting_401866(34953056, +), CAediting_401867(34953059, +), CAediting_401868(34953060, +), CAediting_401869(34953062, +), CAediting_401870(34953070, +), CAediting_401871(34953071, +), CAediting_401872(34953078, +), CAediting_401873(34953082, +), CAediting_401874(34953095, +), CAediting_401875(34953099, +), CAediting_401876(34953100, +), CAediting_401877(34953120, +), CAediting_401878(34953132, +), CAediting_401879(34953293, +), CAediting_401880(34953301, +), CAediting_401881(34953306, +), CAediting_401882(34953310, +), CAediting_401883(34953313, +), CAediting_401884(34953317, +), CAediting_401885(34953325, +), CAediting_401886(34953336, +), CAediting_401887(34953341, +), CAediting_401888(34953361, +), CAediting_401889(34953362, +), CAediting_401890(34953386, +), CAediting_401891(34953387, +), CAediting_401892(34953390, +), CAediting_401893(34953391, +), CAediting_401894(34953397, +), CAediting_401895(34953402, +), CAediting_401896(34953416, +), CAediting_401897(34953427, +), CAediting_401898(34953434, +), CAediting_401899(34953442, +), CAediting_401900(34953443, +), CAediting_401901(34953445, +), CAediting_401902(34953447, +), CAediting_401903(34953460, +), CAediting_401904(34953472, +), CAediting_401905(34953473, +), CAediting_401906(34953484, +), CAediting_401907(34953502, +), CAediting_401908(34953523, +), CAediting_401909(34953524, +), CAediting_401910(34953525, +), CAediting_401911(34953537, +), CAediting_401912(34953539, +), CAediting_401913(34953546, +), CAediting_401914(34953577, +), CAediting_401915(34955798, +), CAediting_401916(34955799, +), CAediting_401917(34955804, +), CAediting_401918(34955906, +), CAediting_401919(34955974, +), CAediting_401920(34955994, +),

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RNA editing positional annotations for DNAJC21 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_401810chr5_34932235_+intronic
CAediting_401811chr5_34933459_+intronic
CAediting_401812chr5_34933460_+intronic
CAediting_401813chr5_34937981_+ncRNA_intronic
CAediting_401814chr5_34941261_+ncRNA_intronic
CAediting_401815chr5_34941331_+ncRNA_intronic
CAediting_401816chr5_34943018_+ncRNA_intronic
CAediting_401817chr5_34945097_+ncRNA_intronic
CAediting_401818chr5_34945195_+ncRNA_intronic
CAediting_401819chr5_34945204_+ncRNA_intronic
CAediting_401820chr5_34945278_+ncRNA_intronic
CAediting_401821chr5_34945330_+ncRNA_intronic
CAediting_401822chr5_34950669_+ncRNA_exonic
CAediting_401823chr5_34950984_+ncRNA_exonic
CAediting_401824chr5_34951628_+ncRNA_exonic
CAediting_401825chr5_34951645_+ncRNA_exonic
CAediting_401826chr5_34951673_+ncRNA_exonic
CAediting_401827chr5_34951708_+ncRNA_exonic
CAediting_401828chr5_34951726_+ncRNA_exonic
CAediting_401829chr5_34951733_+ncRNA_exonic
CAediting_401830chr5_34951735_+ncRNA_exonic
CAediting_401831chr5_34951748_+ncRNA_exonic
CAediting_401832chr5_34951755_+ncRNA_exonic
CAediting_401833chr5_34951763_+ncRNA_exonic
CAediting_401834chr5_34951781_+ncRNA_exonic
CAediting_401835chr5_34951785_+ncRNA_exonic
CAediting_401836chr5_34951786_+ncRNA_exonic
CAediting_401837chr5_34952858_+ncRNA_intronic
CAediting_401838chr5_34952873_+ncRNA_intronic
CAediting_401839chr5_34952877_+ncRNA_intronic
CAediting_401840chr5_34952887_+ncRNA_intronic
CAediting_401841chr5_34952895_+ncRNA_intronic
CAediting_401842chr5_34952912_+ncRNA_intronic
CAediting_401843chr5_34952931_+ncRNA_intronic
CAediting_401844chr5_34952934_+ncRNA_intronic
CAediting_401845chr5_34952939_+ncRNA_intronic
CAediting_401846chr5_34952950_+ncRNA_intronic
CAediting_401847chr5_34952970_+ncRNA_intronic
CAediting_401848chr5_34952971_+ncRNA_intronic
CAediting_401849chr5_34952984_+ncRNA_intronic
CAediting_401850chr5_34952988_+ncRNA_intronic
CAediting_401851chr5_34952989_+ncRNA_intronic
CAediting_401852chr5_34952990_+ncRNA_intronic
CAediting_401853chr5_34952991_+ncRNA_intronic
CAediting_401854chr5_34952992_+ncRNA_intronic
CAediting_401855chr5_34952994_+ncRNA_intronic
CAediting_401856chr5_34952997_+ncRNA_intronic
CAediting_401857chr5_34952998_+ncRNA_intronic
CAediting_401858chr5_34953000_+ncRNA_intronic
CAediting_401859chr5_34953003_+ncRNA_intronic
CAediting_401860chr5_34953008_+ncRNA_intronic
CAediting_401861chr5_34953019_+ncRNA_intronic
CAediting_401862chr5_34953029_+ncRNA_intronic
CAediting_401863chr5_34953030_+ncRNA_intronic
CAediting_401864chr5_34953035_+ncRNA_intronic
CAediting_401865chr5_34953046_+ncRNA_intronic
CAediting_401866chr5_34953056_+ncRNA_intronic
CAediting_401867chr5_34953059_+ncRNA_intronic
CAediting_401868chr5_34953060_+ncRNA_intronic
CAediting_401869chr5_34953062_+ncRNA_intronic
CAediting_401870chr5_34953070_+ncRNA_intronic
CAediting_401871chr5_34953071_+ncRNA_intronic
CAediting_401872chr5_34953078_+ncRNA_intronic
CAediting_401873chr5_34953082_+ncRNA_intronic
CAediting_401874chr5_34953095_+ncRNA_intronic
CAediting_401875chr5_34953099_+ncRNA_intronic
CAediting_401876chr5_34953100_+ncRNA_intronic
CAediting_401877chr5_34953120_+ncRNA_intronic
CAediting_401878chr5_34953132_+ncRNA_intronic
CAediting_401879chr5_34953293_+ncRNA_intronic
CAediting_401880chr5_34953301_+ncRNA_intronic
CAediting_401881chr5_34953306_+ncRNA_intronic
CAediting_401882chr5_34953310_+ncRNA_intronic
CAediting_401883chr5_34953313_+ncRNA_intronic
CAediting_401884chr5_34953317_+ncRNA_intronic
CAediting_401885chr5_34953325_+ncRNA_intronic
CAediting_401886chr5_34953336_+ncRNA_intronic
CAediting_401887chr5_34953341_+ncRNA_intronic
CAediting_401888chr5_34953361_+ncRNA_intronic
CAediting_401889chr5_34953362_+ncRNA_intronic
CAediting_401890chr5_34953386_+ncRNA_intronic
CAediting_401891chr5_34953387_+ncRNA_intronic
CAediting_401892chr5_34953390_+ncRNA_intronic
CAediting_401893chr5_34953391_+ncRNA_intronic
CAediting_401894chr5_34953397_+ncRNA_intronic
CAediting_401895chr5_34953402_+ncRNA_intronic
CAediting_401896chr5_34953416_+ncRNA_intronic
CAediting_401897chr5_34953427_+ncRNA_intronic
CAediting_401898chr5_34953434_+ncRNA_intronic
CAediting_401899chr5_34953442_+ncRNA_intronic
CAediting_401900chr5_34953443_+ncRNA_intronic
CAediting_401901chr5_34953445_+ncRNA_intronic
CAediting_401902chr5_34953447_+ncRNA_intronic
CAediting_401903chr5_34953460_+ncRNA_intronic
CAediting_401904chr5_34953472_+ncRNA_intronic
CAediting_401905chr5_34953473_+ncRNA_intronic
CAediting_401906chr5_34953484_+ncRNA_intronic
CAediting_401907chr5_34953502_+ncRNA_intronic
CAediting_401908chr5_34953523_+ncRNA_intronic
CAediting_401909chr5_34953524_+ncRNA_intronic
CAediting_401910chr5_34953525_+ncRNA_intronic
CAediting_401911chr5_34953537_+ncRNA_exonic
CAediting_401912chr5_34953539_+ncRNA_exonic
CAediting_401913chr5_34953546_+ncRNA_exonic
CAediting_401914chr5_34953577_+ncRNA_exonic
CAediting_401915chr5_34955798_+UTR3
CAediting_401916chr5_34955799_+UTR3
CAediting_401917chr5_34955804_+UTR3
CAediting_401918chr5_34955906_+UTR3
CAediting_401919chr5_34955974_+UTR3
CAediting_401920chr5_34955994_+UTR3

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_401810chr5_34932235_+SINEAluAluSc
CAediting_401811chr5_34933459_+SINEAluAluSz
CAediting_401812chr5_34933460_+SINEAluAluSz
CAediting_401813chr5_34937981_+SINEAluAluSz
CAediting_401814chr5_34941261_+SINEAluAluJb
CAediting_401815chr5_34941331_+SINEAluAluJb
CAediting_401816chr5_34943018_+SINEAluAluSp
CAediting_401817chr5_34945097_+SINEAluAluSx
CAediting_401818chr5_34945195_+SINEAluAluSx
CAediting_401819chr5_34945204_+SINEAluAluSx
CAediting_401820chr5_34945278_+SINEAluAluSx
CAediting_401821chr5_34945330_+SINEAluAluSx
CAediting_401824chr5_34951628_+SINEAluAluSx3
CAediting_401825chr5_34951645_+SINEAluAluSx3
CAediting_401826chr5_34951673_+SINEAluAluSx3
CAediting_401827chr5_34951708_+SINEAluAluSx3
CAediting_401828chr5_34951726_+SINEAluAluSx3
CAediting_401829chr5_34951733_+SINEAluAluSx3
CAediting_401830chr5_34951735_+SINEAluAluSx3
CAediting_401831chr5_34951748_+SINEAluAluSx3
CAediting_401832chr5_34951755_+SINEAluAluSx3
CAediting_401833chr5_34951763_+SINEAluAluSx3
CAediting_401834chr5_34951781_+SINEAluAluSx3
CAediting_401835chr5_34951785_+SINEAluAluSx3
CAediting_401836chr5_34951786_+SINEAluAluSx3
CAediting_401838chr5_34952873_+SINEAluAluSg
CAediting_401839chr5_34952877_+SINEAluAluSg
CAediting_401840chr5_34952887_+SINEAluAluSg
CAediting_401841chr5_34952895_+SINEAluAluSg
CAediting_401842chr5_34952912_+SINEAluAluSg
CAediting_401843chr5_34952931_+SINEAluAluSg
CAediting_401844chr5_34952934_+SINEAluAluSg
CAediting_401845chr5_34952939_+SINEAluAluSg
CAediting_401846chr5_34952950_+SINEAluAluSg
CAediting_401847chr5_34952970_+SINEAluAluSg
CAediting_401848chr5_34952971_+SINEAluAluSg
CAediting_401849chr5_34952984_+SINEAluAluSg
CAediting_401850chr5_34952988_+SINEAluAluSg
CAediting_401851chr5_34952989_+SINEAluAluSg
CAediting_401852chr5_34952990_+SINEAluAluSg
CAediting_401853chr5_34952991_+SINEAluAluSg
CAediting_401854chr5_34952992_+SINEAluAluSg
CAediting_401855chr5_34952994_+SINEAluAluSg
CAediting_401856chr5_34952997_+SINEAluAluSg
CAediting_401857chr5_34952998_+SINEAluAluSg
CAediting_401858chr5_34953000_+SINEAluAluSg
CAediting_401859chr5_34953003_+SINEAluAluSg
CAediting_401860chr5_34953008_+SINEAluAluSg
CAediting_401861chr5_34953019_+SINEAluAluSg
CAediting_401862chr5_34953029_+SINEAluAluSg
CAediting_401863chr5_34953030_+SINEAluAluSg
CAediting_401864chr5_34953035_+SINEAluAluSg
CAediting_401865chr5_34953046_+SINEAluAluSg
CAediting_401866chr5_34953056_+SINEAluAluSg
CAediting_401867chr5_34953059_+SINEAluAluSg
CAediting_401868chr5_34953060_+SINEAluAluSg
CAediting_401869chr5_34953062_+SINEAluAluSg
CAediting_401870chr5_34953070_+SINEAluAluSg
CAediting_401871chr5_34953071_+SINEAluAluSg
CAediting_401872chr5_34953078_+SINEAluAluSg
CAediting_401873chr5_34953082_+SINEAluAluSg
CAediting_401874chr5_34953095_+SINEAluAluSg
CAediting_401875chr5_34953099_+SINEAluAluSg
CAediting_401876chr5_34953100_+SINEAluAluSg
CAediting_401877chr5_34953120_+SINEAluAluSg
CAediting_401878chr5_34953132_+SINEAluAluSg
CAediting_401879chr5_34953293_+SINEAluAluSx1
CAediting_401880chr5_34953301_+SINEAluAluSx1
CAediting_401881chr5_34953306_+SINEAluAluSx1
CAediting_401882chr5_34953310_+SINEAluAluSx1
CAediting_401883chr5_34953313_+SINEAluAluSx1
CAediting_401884chr5_34953317_+SINEAluAluSx1
CAediting_401885chr5_34953325_+SINEAluAluSx1
CAediting_401886chr5_34953336_+SINEAluAluSx1
CAediting_401887chr5_34953341_+SINEAluAluSx1
CAediting_401888chr5_34953361_+SINEAluAluSx1
CAediting_401889chr5_34953362_+SINEAluAluSx1
CAediting_401890chr5_34953386_+SINEAluAluSx1
CAediting_401891chr5_34953387_+SINEAluAluSx1
CAediting_401892chr5_34953390_+SINEAluAluSx1
CAediting_401893chr5_34953391_+SINEAluAluSx1
CAediting_401894chr5_34953397_+SINEAluAluSx1
CAediting_401895chr5_34953402_+SINEAluAluSx1
CAediting_401896chr5_34953416_+SINEAluAluSx1
CAediting_401897chr5_34953427_+SINEAluAluSx1
CAediting_401898chr5_34953434_+SINEAluAluSx1
CAediting_401899chr5_34953442_+SINEAluAluSx1
CAediting_401900chr5_34953443_+SINEAluAluSx1
CAediting_401901chr5_34953445_+SINEAluAluSx1
CAediting_401902chr5_34953447_+SINEAluAluSx1
CAediting_401903chr5_34953460_+SINEAluAluSx1
CAediting_401904chr5_34953472_+SINEAluAluSx1
CAediting_401905chr5_34953473_+SINEAluAluSx1
CAediting_401906chr5_34953484_+SINEAluAluSx1
CAediting_401907chr5_34953502_+SINEAluAluSx1
CAediting_401908chr5_34953523_+SINEAluAluSx1
CAediting_401909chr5_34953524_+SINEAluAluSx1
CAediting_401910chr5_34953525_+SINEAluAluSx1
CAediting_401911chr5_34953537_+SINEAluAluSx1
CAediting_401912chr5_34953539_+SINEAluAluSx1
CAediting_401913chr5_34953546_+SINEAluAluSx1
CAediting_401915chr5_34955798_+SINEAluAluYa5
CAediting_401916chr5_34955799_+SINEAluAluYa5
CAediting_401917chr5_34955804_+SINEAluAluYa5
CAediting_401918chr5_34955906_+SINEAluAluYa5
CAediting_401919chr5_34955974_+SINEAluAluYa5
CAediting_401920chr5_34955994_+SINEAluAluYa5

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RNA A-to-I editing events in the alternative splicing sites for DNAJC21

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESCAediting_401813chr5_34937981_+34937959:349379813SS3+0iAGCTAATTTTTGTATTTTTAGTA-8.21AGCTAATTTTTGTATTTTTAGTG-8.14
ESCAediting_401813chr5_34937981_+34937962:349379843SS0+1iTAATTTTTGTATTTTTAGTAGTG-16.28TAATTTTTGTATTTTTAGTGGTG-7.53

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000168724.13.DNAJC21.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000168724.13.DNAJC21.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for DNAJC21

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
OV.CAediting_401887.ENSG00000168724.DNAJC21.png
Soverview
THYM.CAediting_401841.ENSG00000168724.DNAJC21.png
Soverview

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Protein coding region RNA A-to-I editings for DNAJC21

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for DNAJC21

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_401915chr5_34955798_+ENSG00000168724.13ENST00000382021hsa-miR-513a-5p34955792349557987mer-m83495578234955799144.00-16.68
CAediting_401915chr5_34955798_+ENSG00000168724.13ENST00000382021hsa-miR-513a-5p34955792349557987mer-m83495578234955799144.00-16.68
CAediting_401915chr5_34955798_+ENSG00000168724.13ENST00000382021hsa-miR-63834955797349558037mer-1a3495577934955803159.00-35.56
CAediting_401916chr5_34955799_+ENSG00000168724.13ENST00000382021hsa-miR-805234955797349558037mer-1a3495578534955803140.00-24.15
CAediting_401919chr5_34955974_+ENSG00000168724.13ENST00000382021hsa-miR-428434955969349559757mer-m83495595934955976148.00-20.34
CAediting_401919chr5_34955974_+ENSG00000168724.13ENST00000382021hsa-miR-443734955970349559767mer-m83495595734955977145.00-18.43
CAediting_401920chr5_34955994_+ENSG00000168724.13ENST00000382021hsa-miR-6784-3p34955993349559986mer3495597734955999147.00-30.55
CAediting_401917chr5_34955804_+ENSG00000168724.13ENST00000382021hsa-miR-371a-3p34955802349558087mer-m83495578734955809145.00-17.36

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_401915chr5_34955798_+ENSG00000168724.13ENST00000382021hsa-miR-10399-5p34955793349557997mer-m83495577934955800144-11.2
CAediting_401916chr5_34955799_+ENSG00000168724.13ENST00000382021hsa-miR-10399-5p34955793349557997mer-m83495577934955800144-11.2
CAediting_401920chr5_34955994_+ENSG00000168724.13ENST00000382021hsa-miR-2276-3p34955988349559947mer-m83495597434955995144-17.09
CAediting_401920chr5_34955994_+ENSG00000168724.13ENST00000382021hsa-miR-441834955990349559956mer3495598034955996142-21.8
CAediting_401918chr5_34955906_+ENSG00000168724.13ENST00000382021hsa-miR-4735-5p34955900349559067mer-m83495588634955907140-4.28
CAediting_401916chr5_34955799_+ENSG00000168724.13ENST00000382021hsa-miR-5089-5p34955797349558037mer-m83495578234955804148-14.13
CAediting_401917chr5_34955804_+ENSG00000168724.13ENST00000382021hsa-miR-5089-5p34955797349558037mer-m83495578234955804148-14.13
CAediting_401917chr5_34955804_+ENSG00000168724.13ENST00000382021hsa-miR-512-3p34955802349558087mer-m83495578834955809149-15.51
CAediting_401917chr5_34955804_+ENSG00000168724.13ENST00000382021hsa-miR-512-3p34955802349558087mer-m83495578834955809149-15.51
CAediting_401915chr5_34955798_+ENSG00000168724.13ENST00000382021hsa-miR-6504-3p34955793349557997mer-m83495577934955800148-14.35
CAediting_401916chr5_34955799_+ENSG00000168724.13ENST00000382021hsa-miR-6504-3p34955793349557997mer-m83495577934955800148-14.35
CAediting_401917chr5_34955804_+ENSG00000168724.13ENST00000382021hsa-miR-6506-5p34955798349558047mer-m83495578334955805144-13.78
CAediting_401915chr5_34955798_+ENSG00000168724.13ENST00000382021hsa-miR-7151-3p34955791349557988mer-1a3495577834955798144-16.51

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1229414chr17_67471546_+ENSG00000168724.13ENST00000382021hsa-miR-548aa34955752349557587mer-m83495573534955759140-10.39
CAediting_396018chr5_1062918_-ENSG00000168724.13ENST00000382021hsa-miR-463534958746349587527mer-1a3495873234958752146-18.39
CAediting_524911chr7_5495852_-ENSG00000168724.13ENST00000382021hsa-miR-589-3p34956495349565017mer-m83495647934956502157-14.44

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_442554chr5_154685830_+ENSG00000168724.13ENST00000382021hsa-miR-130334956862349568687mer-m83495684834956869145-11.06
CAediting_442554chr5_154685830_+ENSG00000168724.13ENST00000382021hsa-miR-130334957676349576838mer-1a3495766234957683155-18.12
CAediting_1160181chr17_7017644_-ENSG00000168724.13ENST00000382021hsa-miR-195-3p34956887349568937mer-m83495687434956894150-8.38
CAediting_1160181chr17_7017644_-ENSG00000168724.13ENST00000382021hsa-miR-195-3p34956980349569867mer-m83495696634956987152-10.31
CAediting_1160181chr17_7017644_-ENSG00000168724.13ENST00000382021hsa-miR-195-3p34957552349575587mer-m83495753934957559148-14.95
CAediting_393chr1_1167164_+ENSG00000168724.13ENST00000382021hsa-miR-200b-3p34955707349557137mer-m83495569034955714146-14.06
CAediting_396018chr5_1062918_-ENSG00000168724.13ENST00000382021hsa-miR-463534955289349552957mer-m83495527734955296143-13.08
CAediting_228905chr2_188297554_+ENSG00000168724.13ENST00000382021hsa-miR-561-3p34958452349584587mer-m83495843834958459140-3.7
CAediting_228905chr2_188297554_+ENSG00000168724.13ENST00000382021hsa-miR-561-3p34958735349587417mer-m83495871934958742145-7.92
CAediting_1351755chr19_40282625_-ENSG00000168724.13ENST00000382021hsa-miR-64134954930349549378mer-1a3495491334954937151-13.03
CAediting_1351755chr19_40282625_-ENSG00000168724.13ENST00000382021hsa-miR-64134957936349579427mer-m83495792034957943150-11.73

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for DNAJC21

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000382021.2protein_codingSoverviewSoverview
ENST00000512136.1processed_transcriptSoverviewSoverview
ENST00000509626.1retained_intronSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_401915ENST00000382021.2chr5_34955798_+-1661.80-1659.40-1667.00
CAediting_401916ENST00000382021.2chr5_34955799_+-1659.40-1659.40-1667.00
CAediting_401917ENST00000382021.2chr5_34955804_+-1659.40-1659.40-1667.00
CAediting_401918ENST00000382021.2chr5_34955906_+-1660.70-1659.40-1667.00
CAediting_401919ENST00000382021.2chr5_34955974_+-1664.20-1659.40-1667.00
CAediting_401920ENST00000382021.2chr5_34955994_+-1659.10-1659.40-1667.00
CAediting_401822ENST00000512136.1chr5_34950669_+-774.00-767.70-793.60
CAediting_401823ENST00000512136.1chr5_34950984_+-774.20-767.70-793.60
CAediting_401824ENST00000512136.1chr5_34951628_+-770.10-767.70-793.60
CAediting_401825ENST00000512136.1chr5_34951645_+-767.70-767.70-793.60
CAediting_401826ENST00000512136.1chr5_34951673_+-767.50-767.70-793.60
CAediting_401827ENST00000512136.1chr5_34951708_+-774.30-767.70-793.60
CAediting_401828ENST00000512136.1chr5_34951726_+-771.70-767.70-793.60
CAediting_401829ENST00000512136.1chr5_34951733_+-767.70-767.70-793.60
CAediting_401830ENST00000512136.1chr5_34951735_+-767.60-767.70-793.60
CAediting_401831ENST00000512136.1chr5_34951748_+-770.80-767.70-793.60
CAediting_401832ENST00000512136.1chr5_34951755_+-770.60-767.70-793.60
CAediting_401833ENST00000512136.1chr5_34951763_+-771.00-767.70-793.60
CAediting_401834ENST00000512136.1chr5_34951781_+-767.70-767.70-793.60
CAediting_401835ENST00000512136.1chr5_34951785_+-767.80-767.70-793.60
CAediting_401836ENST00000512136.1chr5_34951786_+-770.00-767.70-793.60
CAediting_401911ENST00000509626.1chr5_34953537_+-174.20-174.60-177.60
CAediting_401912ENST00000509626.1chr5_34953539_+-174.80-174.60-177.60
CAediting_401913ENST00000509626.1chr5_34953546_+-176.60-174.60-177.60
CAediting_401914ENST00000509626.1chr5_34953577_+-176.70-174.60-177.60

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Relation with ADAR for DNAJC21

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
BLCACAediting_401841chr5_34952895_+0.001602673977393920.270034228782129....
BRCACAediting_401841chr5_34952895_+1.27860418268888e-080.299856279844757....
CESCCAediting_401841chr5_34952895_+0.008709565581825040.217122955604364....
LUADCAediting_401841chr5_34952895_+5.25476578851618e-050.293533662737162....
COADCAediting_401841chr5_34952895_+0.004157448712519580.307828791762658....
LUSCCAediting_401841chr5_34952895_+2.64126881369269e-060.292587436674468....
PRADCAediting_401841chr5_34952895_+0.0388443364161170.251144585182894....
HNSCCAediting_401841chr5_34952895_+0.0002060478188870850.285930702649955....
SKCMCAediting_401841chr5_34952895_+9.00162277227798e-070.481441913423825....
SARCCAediting_401841chr5_34952895_+8.36397636526089e-060.427226220835476....
BRCACAediting_401859chr5_34953003_+0.0009094977697040460.230525532972345....
LUSCCAediting_401859chr5_34953003_+0.0004399202520804860.310934754081946....
BRCACAediting_401863chr5_34953030_+0.02869119014039450.234655113091366....
BRCACAediting_401866chr5_34953056_+0.01717189722695250.335656269193185....
BLCACAediting_401883chr5_34953313_+0.001022557979608690.331751913340291....
BRCACAediting_401883chr5_34953313_+4.04845919583451e-130.45003310599946....
CESCCAediting_401883chr5_34953313_+0.0001375574160217220.352565412931266....
LUADCAediting_401883chr5_34953313_+1.40983504418427e-060.448674563196641....
LUSCCAediting_401883chr5_34953313_+3.69526950393723e-050.321998694554347....
HNSCCAediting_401883chr5_34953313_+..0.01195656284088980.237822518750978..
OVCAediting_401883chr5_34953313_+0.01827577124911090.281412708186577....
SKCMCAediting_401883chr5_34953313_+0.0002547481550155670.44209592311843....
SARCCAediting_401883chr5_34953313_+3.46783904110247e-050.523533778518278....
BLCACAediting_401887chr5_34953341_+0.001933799673570910.405476017565103....
OVCAediting_401887chr5_34953341_+0.02010392161752970.304549318904713....
BLCACAediting_401893chr5_34953391_+0.02734196305817480.248317544287203....
LUADCAediting_401893chr5_34953391_+5.26435886528393e-070.538390524016904....
LUSCCAediting_401893chr5_34953391_+0.0007621478714404150.341276515904702....
HNSCCAediting_401893chr5_34953391_+..0.01524816817814190.341404331541698..
BRCACAediting_401899chr5_34953442_+1.45222471634639e-060.438828405022836....
LUADCAediting_401899chr5_34953442_+0.002286035275653310.380451783924797....
LUSCCAediting_401899chr5_34953442_+0.007493940376708380.278595801889773....
BLCACAediting_401905chr5_34953473_+0.01569920295125190.2877918532871370.02131779935915670.274805536113179..
BRCACAediting_401905chr5_34953473_+0.007439035139245510.266152692641512....
LUADCAediting_401905chr5_34953473_+0.002596207461203070.357078443360134....
LUSCCAediting_401905chr5_34953473_+0.0009507812059757920.267141372488457....
BRCACAediting_401912chr5_34953539_+0.0002067940703052420.497073255325405....
STADCAediting_401912chr5_34953539_+1.73140066397141e-050.492340573648808....
OVCAediting_401912chr5_34953539_+7.76303786723388e-050.4401595445225310.0197640421304030.268680810238009..

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Relation with cancer stages for DNAJC21

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
BLCApathologic_stageCAediting_401841chr5_34952895_+0.03091388716556060.187246910785165
BLCApathologic_stageCAediting_401893chr5_34953391_+0.03507485056951160.237493153647558
ESCAclinical_stageCAediting_401905chr5_34953473_+0.00845818179589474-0.5716476342332
ESCAclinical_stageCAediting_401910chr5_34953525_+0.000719291977676341-0.706608819160242
LUADpathologic_stageCAediting_401841chr5_34952895_+0.01868331447972480.17467129433116

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Relation with survival for DNAJC21

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for DNAJC21

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for DNAJC21

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
DNAJC21C0030312Pancytopenia2GENOMICS_ENGLAND
DNAJC21C1855710Bone marrow hypocellularity2GENOMICS_ENGLAND
DNAJC21C4310744BONE MARROW FAILURE SYNDROME 32GENOMICS_ENGLAND;UNIPROT
DNAJC21C0272170Shwachman syndrome1CTD_human;ORPHANET