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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: COPA (CAeditome ID:1314)

Gene summary for COPA

check button Gene summary
Gene informationGene symbol

COPA

Gene ID

1314

Gene nameCOPI coat complex subunit alpha
SynonymsAILJK|HEP-COP|alpha-COP
Cytomap

1q23.2

Type of geneprotein-coding
Descriptioncoatomer subunit alphaalpha coat proteincoatomer protein complex subunit alphaproxeninxenin
Modification date20210518
UniProtAcc

P53621

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
COPA

GO:0030157

Coatomer subunit alpha

1429581

COPA

GO:0005615

Coatomer subunit alpha

1429581

COPA

GO:0005737

Coatomer subunit alpha

9115636

COPA

GO:0030426

Coatomer subunit alpha

21300694

COPA

GO:0030126

Coatomer subunit alpha

14729954


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RNA A-to-I events for COPA

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000122218.13
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_115609(160289591, -), CAediting_115610(160289592, -), CAediting_115611(160289683, -), CAediting_115612(160289787, -), CAediting_115613(160289870, -), CAediting_115614(160289872, -), CAediting_115615(160293736, -), CAediting_115616(160294234, -), CAediting_115617(160294244, -), CAediting_115618(160295821, -), CAediting_115619(160297919, -), CAediting_115620(160297995, -), CAediting_115621(160300946, -), CAediting_115622(160300956, -), CAediting_115623(160301010, -), CAediting_115624(160301035, -), CAediting_115625(160302601, -), CAediting_115626(160302627, -), CAediting_115627(160302652, -), CAediting_115628(160302663, -), CAediting_115629(160302666, -), CAediting_115630(160302676, -), CAediting_115631(160302687, -), CAediting_115632(160302693, -), CAediting_115633(160302719, -), CAediting_115634(160302729, -), CAediting_115635(160302749, -), CAediting_115636(160302750, -), CAediting_115637(160302751, -), CAediting_115638(160302759, -), CAediting_115639(160302760, -), CAediting_115640(160302783, -), CAediting_115641(160302826, -), CAediting_115642(160302827, -), CAediting_115643(160302910, -), CAediting_115644(160302928, -), CAediting_115645(160302943, -), CAediting_115646(160302981, -), CAediting_115647(160302988, -), CAediting_115648(160302993, -), CAediting_115649(160303007, -), CAediting_115650(160303010, -), CAediting_115651(160303016, -), CAediting_115652(160303025, -), CAediting_115653(160303033, -), CAediting_115654(160303049, -), CAediting_115655(160303064, -), CAediting_115656(160303086, -), CAediting_115657(160303152, -), CAediting_115658(160303163, -), CAediting_115659(160303185, -), CAediting_115660(160304024, -), CAediting_115661(160304044, -), CAediting_115662(160304091, -), CAediting_115663(160304099, -), CAediting_115664(160304100, -), CAediting_115665(160304111, -), CAediting_115666(160304117, -), CAediting_115667(160304126, -), CAediting_115668(160304130, -), CAediting_115669(160304143, -), CAediting_115670(160304147, -), CAediting_115671(160304152, -), CAediting_115672(160304153, -), CAediting_115673(160304178, -), CAediting_115674(160304193, -), CAediting_115675(160304194, -), CAediting_115676(160304208, -), CAediting_115677(160304217, -), CAediting_115678(160304221, -), CAediting_115679(160304232, -), CAediting_115680(160304241, -), CAediting_115681(160304260, -), CAediting_115682(160304286, -), CAediting_115683(160304287, -), CAediting_115684(160304409, -), CAediting_115685(160304421, -), CAediting_115686(160304422, -), CAediting_115687(160304472, -), CAediting_115688(160304481, -), CAediting_115689(160304484, -), CAediting_115690(160304652, -), CAediting_115691(160323947, -), CAediting_115692(160324056, -), CAediting_115693(160324058, -), CAediting_115694(160324066, -), CAediting_115695(160324067, -), CAediting_115696(160324082, -), CAediting_115697(160324106, -), CAediting_115698(160324133, -), CAediting_115699(160324142, -), CAediting_115700(160324345, -), CAediting_115701(160324351, -), CAediting_115702(160324494, -), CAediting_115703(160324497, -), CAediting_115704(160324501, -), CAediting_115705(160324502, -), CAediting_115706(160324515, -), CAediting_115707(160324543, -), CAediting_115708(160324565, -), CAediting_115709(160324570, -), CAediting_115710(160324577, -), CAediting_115711(160324579, -), CAediting_115712(160326372, -), CAediting_115713(160326419, -), CAediting_115714(160326521, -), CAediting_115715(160326704, -), CAediting_115716(160326734, -), CAediting_115717(160326737, -), CAediting_115718(160326738, -), CAediting_115719(160326744, -), CAediting_115720(160326755, -), CAediting_115721(160326756, -), CAediting_115722(160326757, -), CAediting_115723(160326761, -), CAediting_115724(160327286, -), CAediting_115725(160327349, -), CAediting_115726(160327844, -), CAediting_115727(160328044, -), CAediting_115728(160328045, -), CAediting_115729(160328048, -), CAediting_115730(160328053, -), CAediting_115731(160328061, -), CAediting_115732(160328085, -), CAediting_115733(160328089, -), CAediting_115734(160328125, -), CAediting_115735(160328484, -), CAediting_115736(160331002, -), CAediting_115737(160331387, -), CAediting_115738(160332454, -), CAediting_115739(160333052, -), CAediting_115740(160333082, -), CAediting_115741(160333117, -), CAediting_115742(160333125, -), CAediting_115743(160333127, -), CAediting_115744(160333170, -), CAediting_115745(160333197, -), CAediting_115746(160335694, -),

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RNA editing positional annotations for COPA using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred
CAediting_115738chr1_160332454_-nonsynonymous SNVENST00000241704.7c.A490Gp.I164VDBN
CAediting_115738chr1_160332454_-nonsynonymous SNVENST00000368069.6c.A490Gp.I164VDBN

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_115609chr1_160289591_-UTR3
CAediting_115610chr1_160289592_-UTR3
CAediting_115611chr1_160289683_-UTR3
CAediting_115612chr1_160289787_-UTR3
CAediting_115613chr1_160289870_-UTR3
CAediting_115614chr1_160289872_-UTR3
CAediting_115615chr1_160293736_-intronic
CAediting_115616chr1_160294234_-intronic
CAediting_115617chr1_160294244_-intronic
CAediting_115618chr1_160295821_-exonic
CAediting_115619chr1_160297919_-ncRNA_intronic
CAediting_115620chr1_160297995_-ncRNA_intronic
CAediting_115621chr1_160300946_-intronic
CAediting_115622chr1_160300956_-intronic
CAediting_115623chr1_160301010_-intronic
CAediting_115624chr1_160301035_-intronic
CAediting_115625chr1_160302601_-intronic
CAediting_115626chr1_160302627_-intronic
CAediting_115627chr1_160302652_-intronic
CAediting_115628chr1_160302663_-intronic
CAediting_115629chr1_160302666_-intronic
CAediting_115630chr1_160302676_-intronic
CAediting_115631chr1_160302687_-intronic
CAediting_115632chr1_160302693_-intronic
CAediting_115633chr1_160302719_-intronic
CAediting_115634chr1_160302729_-intronic
CAediting_115635chr1_160302749_-intronic
CAediting_115636chr1_160302750_-intronic
CAediting_115637chr1_160302751_-intronic
CAediting_115638chr1_160302759_-intronic
CAediting_115639chr1_160302760_-intronic
CAediting_115640chr1_160302783_-intronic
CAediting_115641chr1_160302826_-intronic
CAediting_115642chr1_160302827_-intronic
CAediting_115643chr1_160302910_-intronic
CAediting_115644chr1_160302928_-intronic
CAediting_115645chr1_160302943_-intronic
CAediting_115646chr1_160302981_-intronic
CAediting_115647chr1_160302988_-intronic
CAediting_115648chr1_160302993_-intronic
CAediting_115649chr1_160303007_-intronic
CAediting_115650chr1_160303010_-intronic
CAediting_115651chr1_160303016_-intronic
CAediting_115652chr1_160303025_-intronic
CAediting_115653chr1_160303033_-intronic
CAediting_115654chr1_160303049_-intronic
CAediting_115655chr1_160303064_-intronic
CAediting_115656chr1_160303086_-intronic
CAediting_115657chr1_160303152_-intronic
CAediting_115658chr1_160303163_-intronic
CAediting_115659chr1_160303185_-intronic
CAediting_115660chr1_160304024_-intronic
CAediting_115661chr1_160304044_-intronic
CAediting_115662chr1_160304091_-intronic
CAediting_115663chr1_160304099_-intronic
CAediting_115664chr1_160304100_-intronic
CAediting_115665chr1_160304111_-intronic
CAediting_115666chr1_160304117_-intronic
CAediting_115667chr1_160304126_-intronic
CAediting_115668chr1_160304130_-intronic
CAediting_115669chr1_160304143_-intronic
CAediting_115670chr1_160304147_-intronic
CAediting_115671chr1_160304152_-intronic
CAediting_115672chr1_160304153_-intronic
CAediting_115673chr1_160304178_-intronic
CAediting_115674chr1_160304193_-intronic
CAediting_115675chr1_160304194_-intronic
CAediting_115676chr1_160304208_-intronic
CAediting_115677chr1_160304217_-intronic
CAediting_115678chr1_160304221_-intronic
CAediting_115679chr1_160304232_-intronic
CAediting_115680chr1_160304241_-intronic
CAediting_115681chr1_160304260_-intronic
CAediting_115682chr1_160304286_-intronic
CAediting_115683chr1_160304287_-intronic
CAediting_115684chr1_160304409_-intronic
CAediting_115685chr1_160304421_-intronic
CAediting_115686chr1_160304422_-intronic
CAediting_115687chr1_160304472_-intronic
CAediting_115688chr1_160304481_-intronic
CAediting_115689chr1_160304484_-intronic
CAediting_115690chr1_160304652_-intronic
CAediting_115691chr1_160323947_-intronic
CAediting_115692chr1_160324056_-intronic
CAediting_115693chr1_160324058_-intronic
CAediting_115694chr1_160324066_-intronic
CAediting_115695chr1_160324067_-intronic
CAediting_115696chr1_160324082_-intronic
CAediting_115697chr1_160324106_-intronic
CAediting_115698chr1_160324133_-intronic
CAediting_115699chr1_160324142_-intronic
CAediting_115700chr1_160324345_-intronic
CAediting_115701chr1_160324351_-intronic
CAediting_115702chr1_160324494_-intronic
CAediting_115703chr1_160324497_-intronic
CAediting_115704chr1_160324501_-intronic
CAediting_115705chr1_160324502_-intronic
CAediting_115706chr1_160324515_-intronic
CAediting_115707chr1_160324543_-intronic
CAediting_115708chr1_160324565_-intronic
CAediting_115709chr1_160324570_-intronic
CAediting_115710chr1_160324577_-intronic
CAediting_115711chr1_160324579_-intronic
CAediting_115712chr1_160326372_-intronic
CAediting_115713chr1_160326419_-intronic
CAediting_115714chr1_160326521_-intronic
CAediting_115715chr1_160326704_-intronic
CAediting_115716chr1_160326734_-intronic
CAediting_115717chr1_160326737_-intronic
CAediting_115718chr1_160326738_-intronic
CAediting_115719chr1_160326744_-intronic
CAediting_115720chr1_160326755_-intronic
CAediting_115721chr1_160326756_-intronic
CAediting_115722chr1_160326757_-intronic
CAediting_115723chr1_160326761_-intronic
CAediting_115724chr1_160327286_-intronic
CAediting_115725chr1_160327349_-intronic
CAediting_115726chr1_160327844_-intronic
CAediting_115727chr1_160328044_-intronic
CAediting_115728chr1_160328045_-intronic
CAediting_115729chr1_160328048_-intronic
CAediting_115730chr1_160328053_-intronic
CAediting_115731chr1_160328061_-intronic
CAediting_115732chr1_160328085_-intronic
CAediting_115733chr1_160328089_-intronic
CAediting_115734chr1_160328125_-intronic
CAediting_115735chr1_160328484_-intronic
CAediting_115736chr1_160331002_-intronic
CAediting_115737chr1_160331387_-intronic
CAediting_115738chr1_160332454_-exonic
CAediting_115739chr1_160333052_-intronic
CAediting_115740chr1_160333082_-intronic
CAediting_115741chr1_160333117_-intronic
CAediting_115742chr1_160333125_-intronic
CAediting_115743chr1_160333127_-intronic
CAediting_115744chr1_160333170_-intronic
CAediting_115745chr1_160333197_-intronic
CAediting_115746chr1_160335694_-ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_115609chr1_160289591_-SINEAluAluSz6
CAediting_115610chr1_160289592_-SINEAluAluSz6
CAediting_115611chr1_160289683_-SINEAluAluSz6
CAediting_115612chr1_160289787_-SINEAluAluSz6
CAediting_115613chr1_160289870_-SINEAluAluSz6
CAediting_115614chr1_160289872_-SINEAluAluSz6
CAediting_115615chr1_160293736_-SINEAluAluJb
CAediting_115616chr1_160294234_-SINEAluAluJo
CAediting_115617chr1_160294244_-SINEAluAluJo
CAediting_115619chr1_160297919_-SINEAluAluSx3
CAediting_115620chr1_160297995_-SINEAluAluSx3
CAediting_115621chr1_160300946_-SINEAluAluSz6
CAediting_115622chr1_160300956_-SINEAluAluSz6
CAediting_115623chr1_160301010_-SINEAluAluSz6
CAediting_115624chr1_160301035_-SINEAluAluSz6
CAediting_115625chr1_160302601_-SINEAluAluY
CAediting_115626chr1_160302627_-SINEAluAluY
CAediting_115627chr1_160302652_-SINEAluAluY
CAediting_115628chr1_160302663_-SINEAluAluY
CAediting_115629chr1_160302666_-SINEAluAluY
CAediting_115630chr1_160302676_-SINEAluAluY
CAediting_115631chr1_160302687_-SINEAluAluY
CAediting_115632chr1_160302693_-SINEAluAluY
CAediting_115633chr1_160302719_-SINEAluAluY
CAediting_115634chr1_160302729_-SINEAluAluY
CAediting_115635chr1_160302749_-SINEAluAluY
CAediting_115636chr1_160302750_-SINEAluAluY
CAediting_115637chr1_160302751_-SINEAluAluY
CAediting_115638chr1_160302759_-SINEAluAluY
CAediting_115639chr1_160302760_-SINEAluAluY
CAediting_115640chr1_160302783_-SINEAluAluY
CAediting_115641chr1_160302826_-SINEAluAluY
CAediting_115642chr1_160302827_-SINEAluAluY
CAediting_115643chr1_160302910_-SINEAluAluSz
CAediting_115644chr1_160302928_-SINEAluAluSz
CAediting_115645chr1_160302943_-SINEAluAluSz
CAediting_115646chr1_160302981_-SINEAluAluSz
CAediting_115647chr1_160302988_-SINEAluAluSz
CAediting_115648chr1_160302993_-SINEAluAluSz
CAediting_115649chr1_160303007_-SINEAluAluSz
CAediting_115650chr1_160303010_-SINEAluAluSz
CAediting_115651chr1_160303016_-SINEAluAluSz
CAediting_115652chr1_160303025_-SINEAluAluSz
CAediting_115653chr1_160303033_-SINEAluAluSz
CAediting_115654chr1_160303049_-SINEAluAluSz
CAediting_115655chr1_160303064_-SINEAluAluSz
CAediting_115656chr1_160303086_-SINEAluAluSz
CAediting_115657chr1_160303152_-SINEAluAluSz
CAediting_115658chr1_160303163_-SINEAluAluSz
CAediting_115659chr1_160303185_-SINEAluAluSz
CAediting_115660chr1_160304024_-SINEAluAluSp
CAediting_115661chr1_160304044_-SINEAluAluSp
CAediting_115662chr1_160304091_-SINEAluAluSp
CAediting_115663chr1_160304099_-SINEAluAluSp
CAediting_115664chr1_160304100_-SINEAluAluSp
CAediting_115665chr1_160304111_-SINEAluAluSp
CAediting_115666chr1_160304117_-SINEAluAluSp
CAediting_115667chr1_160304126_-SINEAluAluSp
CAediting_115668chr1_160304130_-SINEAluAluSp
CAediting_115669chr1_160304143_-SINEAluAluSp
CAediting_115670chr1_160304147_-SINEAluAluSp
CAediting_115671chr1_160304152_-SINEAluAluSp
CAediting_115672chr1_160304153_-SINEAluAluSp
CAediting_115673chr1_160304178_-SINEAluAluSp
CAediting_115674chr1_160304193_-SINEAluAluSp
CAediting_115675chr1_160304194_-SINEAluAluSp
CAediting_115676chr1_160304208_-SINEAluAluSp
CAediting_115677chr1_160304217_-SINEAluAluSp
CAediting_115678chr1_160304221_-SINEAluAluSp
CAediting_115679chr1_160304232_-SINEAluAluSp
CAediting_115680chr1_160304241_-SINEAluAluSp
CAediting_115681chr1_160304260_-SINEAluAluSp
CAediting_115682chr1_160304286_-SINEAluAluSp
CAediting_115683chr1_160304287_-SINEAluAluSp
CAediting_115684chr1_160304409_-SINEAluAluSg
CAediting_115685chr1_160304421_-SINEAluAluSg
CAediting_115686chr1_160304422_-SINEAluAluSg
CAediting_115687chr1_160304472_-SINEAluAluSg
CAediting_115688chr1_160304481_-SINEAluAluSg
CAediting_115689chr1_160304484_-SINEAluAluSg
CAediting_115690chr1_160304652_-SINEAluAluSg
CAediting_115691chr1_160323947_-SINEAluAluSg7
CAediting_115692chr1_160324056_-SINEAluAluSg7
CAediting_115693chr1_160324058_-SINEAluAluSg7
CAediting_115694chr1_160324066_-SINEAluAluSg7
CAediting_115695chr1_160324067_-SINEAluAluSg7
CAediting_115696chr1_160324082_-SINEAluAluSg7
CAediting_115697chr1_160324106_-SINEAluAluSg7
CAediting_115698chr1_160324133_-SINEAluAluSg7
CAediting_115699chr1_160324142_-SINEAluAluSg7
CAediting_115700chr1_160324345_-SINEAluAluJr
CAediting_115701chr1_160324351_-SINEAluAluJr
CAediting_115702chr1_160324494_-SINEAluAluJr
CAediting_115703chr1_160324497_-SINEAluAluJr
CAediting_115704chr1_160324501_-SINEAluAluJr
CAediting_115705chr1_160324502_-SINEAluAluJr
CAediting_115706chr1_160324515_-SINEAluAluJr
CAediting_115707chr1_160324543_-SINEAluAluJr
CAediting_115708chr1_160324565_-SINEAluAluJr
CAediting_115709chr1_160324570_-SINEAluAluJr
CAediting_115710chr1_160324577_-SINEAluAluJr
CAediting_115711chr1_160324579_-SINEAluAluJr
CAediting_115712chr1_160326372_-SINEAluAluJb
CAediting_115713chr1_160326419_-SINEAluAluJb
CAediting_115714chr1_160326521_-SINEAluAluJb
CAediting_115724chr1_160327286_-SINEAluAluSx
CAediting_115725chr1_160327349_-SINEAluAluSx
CAediting_115726chr1_160327844_-SINEAluAluSx
CAediting_115736chr1_160331002_-SINEAluAluSx
CAediting_115737chr1_160331387_-SINEAluAluSx
CAediting_115739chr1_160333052_-SINEAluAluSx
CAediting_115740chr1_160333082_-SINEAluAluSx
CAediting_115741chr1_160333117_-SINEAluAluSx
CAediting_115742chr1_160333125_-SINEAluAluSx
CAediting_115743chr1_160333127_-SINEAluAluSx
CAediting_115744chr1_160333170_-SINEAluAluSx
CAediting_115745chr1_160333197_-SINEAluAluSx
CAediting_115746chr1_160335694_-SINEAluAluSc8

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RNA A-to-I editing events in the alternative splicing sites for COPA

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000122218.13.COPA.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000122218.13.COPA.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for COPA

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
BRCA.CAediting_115738.ENSG00000122218.COPA.png
Soverview
LUAD.CAediting_115738.ENSG00000122218.COPA.png
Soverview
STAD.CAediting_115738.ENSG00000122218.COPA.png
Soverview

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Protein coding region RNA A-to-I editings for COPA

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.
all structure


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The effects of the RNA editing to the miRNA binding sites for COPA

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_115611chr1_160289683_-ENSG00000122218.13ENST00000368069hsa-miR-4726-3p1602896801602896878mer-1a160289680160289701150.00-19.15
CAediting_115610chr1_160289592_-ENSG00000122218.13ENST00000368069hsa-miR-204-5p1602895901602895978mer-1a160289590160289611142.00-10.74
CAediting_115610chr1_160289592_-ENSG00000122218.13ENST00000368069hsa-miR-211-5p1602895901602895978mer-1a160289590160289611145.00-10.74
CAediting_115610chr1_160289592_-ENSG00000122218.13ENST00000368069hsa-miR-4446-5p1602895891602895957mer-m8160289588160289609140.00-12.61
CAediting_115610chr1_160289592_-ENSG00000122218.13ENST00000368069hsa-miR-4755-5p1602895891602895968mer-1a160289589160289610140.00-12.37
CAediting_115610chr1_160289592_-ENSG00000122218.13ENST00000368069hsa-miR-5006-3p1602895891602895968mer-1a160289589160289609145.00-12.16
CAediting_115610chr1_160289592_-ENSG00000122218.13ENST00000368069hsa-miR-6832-3p1602895911602895988mer-1a160289591160289610159.00-9.61

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_115612chr1_160289787_-ENSG00000122218.13ENST00000368069hsa-miR-4659a-5p1602897861602897938mer-1a160289786160289810148-13.22
CAediting_115612chr1_160289787_-ENSG00000122218.13ENST00000368069hsa-miR-4659b-5p1602897861602897938mer-1a160289786160289807148-15.33
CAediting_115612chr1_160289787_-ENSG00000122218.13ENST00000368069hsa-miR-4776-3p1602897861602897927mer-m8160289785160289807155-18.54
CAediting_115612chr1_160289787_-ENSG00000122218.13ENST00000368069hsa-miR-4776-3p1602897861602897927mer-m8160289785160289807155-18.54
CAediting_115611chr1_160289683_-ENSG00000122218.13ENST00000368069hsa-miR-5571-3p1602896801602896867mer-m8160289679160289702143-15.68
CAediting_115612chr1_160289787_-ENSG00000122218.13ENST00000368069hsa-miR-6501-5p1602897841602897918mer-1a160289784160289805148-18.01
CAediting_115611chr1_160289683_-ENSG00000122218.13ENST00000368069hsa-miR-660-3p1602896781602896836mer160289677160289698146-19.9
CAediting_115614chr1_160289872_-ENSG00000122218.13ENST00000368069hsa-miR-6807-5p1602898721602898787mer-m8160289871160289892142-14.55
CAediting_115612chr1_160289787_-ENSG00000122218.13ENST00000368069hsa-miR-744-3p1602897841602897907mer-m8160289783160289804145-11.41

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_228905chr2_188297554_+ENSG00000122218.13ENST00000368069hsa-miR-561-3p1602898921602898987mer-m8160289891160289916154-20
CAediting_228905chr2_188297554_+ENSG00000122218.13ENST00000368069hsa-miR-561-3p1602895851602895917mer-m8160289584160289601144-15.8

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for COPA

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000241704.7protein_codingSoverviewSoverview
ENST00000368069.6protein_codingSoverviewSoverview
ENST00000545284.1retained_intronSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_115609ENST00000241704.7chr1_160289591_--1567.20-1565.60-1578.90
CAediting_115610ENST00000241704.7chr1_160289592_--1568.00-1565.60-1578.90
CAediting_115611ENST00000241704.7chr1_160289683_--1566.70-1565.60-1578.90
CAediting_115612ENST00000241704.7chr1_160289787_--1566.90-1565.60-1578.90
CAediting_115613ENST00000241704.7chr1_160289870_--1569.30-1565.60-1578.90
CAediting_115614ENST00000241704.7chr1_160289872_--1565.80-1565.60-1578.90
CAediting_115618ENST00000241704.7chr1_160295821_--1566.50-1565.60-1578.90
CAediting_115738ENST00000241704.7chr1_160332454_--1569.80-1565.60-1578.90
CAediting_115609ENST00000368069.6chr1_160289591_--1508.90-1505.80-1515.90
CAediting_115610ENST00000368069.6chr1_160289592_--1509.70-1505.80-1515.90
CAediting_115611ENST00000368069.6chr1_160289683_--1506.90-1505.80-1515.90
CAediting_115612ENST00000368069.6chr1_160289787_--1507.10-1505.80-1515.90
CAediting_115613ENST00000368069.6chr1_160289870_--1509.50-1505.80-1515.90
CAediting_115614ENST00000368069.6chr1_160289872_--1506.00-1505.80-1515.90
CAediting_115618ENST00000368069.6chr1_160295821_--1506.50-1505.80-1515.90
CAediting_115738ENST00000368069.6chr1_160332454_--1508.00-1505.80-1515.90
CAediting_115618ENST00000545284.1chr1_160295821_--265.80-265.10-265.80

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Relation with ADAR for COPA

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
LAMLCAediting_115718chr1_160326738_-0.03359256504575740.28447604135235....
LAMLCAediting_115721chr1_160326756_-....0.0009181803108838210.332937250777246
BLCACAediting_115738chr1_160332454_-..0.01157835455655670.272673557714208..
LGGCAediting_115738chr1_160332454_-..0.006506678582234010.125352945786031..
BRCACAediting_115738chr1_160332454_-..3.2445479657975e-050.18865880870932..
LIHCCAediting_115738chr1_160332454_-..0.03392702489689970.250341273482424..
LUADCAediting_115738chr1_160332454_-..0.02962136125911170.212384077804283..
LUSCCAediting_115738chr1_160332454_-..1.45455130328301e-070.468613341585712..
GBMCAediting_115738chr1_160332454_-..1.42878235059066e-110.50994021822198..
HNSCCAediting_115738chr1_160332454_-..1.2633741810721e-080.380139160521168..
STADCAediting_115738chr1_160332454_-..7.2368458750604e-070.489771352783016..
KIRCCAediting_115738chr1_160332454_-..1.28026548187879e-180.394124079083375..
KIRPCAediting_115738chr1_160332454_-..0.0006920462628181360.338630943518289..
PAADCAediting_115738chr1_160332454_-..4.06137535252718e-100.539705743682837..
SKCMCAediting_115738chr1_160332454_-..1.79134604530505e-310.557765552155571..
UVMCAediting_115738chr1_160332454_-..5.47180983289936e-100.745059522163945..
MESOCAediting_115738chr1_160332454_-..0.0001051512135389450.446911575393562..
SARCCAediting_115738chr1_160332454_-..5.3267020527242e-100.427019347625564..
THYMCAediting_115738chr1_160332454_-..7.13394613799507e-110.754023080809606..

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Relation with cancer stages for COPA

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
BLCApathologic_stageCAediting_115738chr1_160332454_-0.00937664651355561-0.28027135411631
THCApathologic_stageCAediting_115738chr1_160332454_-0.002947798509419280.286106206853841

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Relation with survival for COPA

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for COPA

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for COPA

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
COPAC4225334AUTOIMMUNE INTERSTITIAL LUNG, JOINT, AND KIDNEY DISEASE2CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
COPAC0003864Arthritis1CTD_human
COPAC0004364Autoimmune Diseases1CTD_human
COPAC0162323Polyarthritis1CTD_human
COPAC0206061Pneumonia, Interstitial1CTD_human
COPAC0206062Lung Diseases, Interstitial1CTD_human
COPAC3860213Autoinflammatory disorder1GENOMICS_ENGLAND