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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: ADH1C (CAeditome ID:126) |
Gene summary for ADH1C |
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Gene information | Gene symbol | ADH1C | Gene ID | 126 |
Gene name | alcohol dehydrogenase 1C (class I), gamma polypeptide | |
Synonyms | ADH3 | |
Cytomap | 4q23 | |
Type of gene | protein-coding | |
Description | alcohol dehydrogenase 1CADH, gamma subunitalcohol dehydrogenase 3 (class I), gamma polypeptidealdehyde reductase | |
Modification date | 20210518 | |
UniProtAcc | P00326 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
ADH1C | GO:0004022 | Alcohol dehydrogenase 1C | 6391957 |
ADH1C | GO:0006069 | Alcohol dehydrogenase 1C | 6391957 |
ADH1C | GO:0005654 | Alcohol dehydrogenase 1C | 0000052 |
ADH1C | GO:0005829 | Alcohol dehydrogenase 1C | 0000052 |
ADH1C | GO:0005886 | Alcohol dehydrogenase 1C | 0000052 |
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RNA A-to-I events for ADH1C |
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CAediting_377673(99345202, -), CAediting_377674(99345205, -), |
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RNA editing positional annotations for ADH1C using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
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CAeditome ID | Position | Variant type |
CAediting_377673 | chr4_99345202_- | exonic |
CAediting_377674 | chr4_99345205_- | exonic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
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RNA A-to-I editing events in the alternative splicing sites for ADH1C |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ADH1C |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for ADH1C |
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The effects of the RNA editing to the miRNA binding sites for ADH1C |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for ADH1C |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
CAediting_377673 | ENST00000505942.2 | chr4_99345202_- | -183.30 | -182.90 | -183.70 |
CAediting_377674 | ENST00000505942.2 | chr4_99345205_- | -182.90 | -182.90 | -183.70 |
CAediting_377673 | ENST00000510055.4 | chr4_99345202_- | -303.20 | -302.30 | -302.10 |
CAediting_377674 | ENST00000510055.4 | chr4_99345205_- | -302.30 | -302.30 | -302.10 |
CAediting_377673 | ENST00000511397.3 | chr4_99345202_- | -200.40 | -199.60 | -199.40 |
CAediting_377674 | ENST00000511397.3 | chr4_99345205_- | -199.60 | -199.60 | -199.40 |
CAediting_377673 | ENST00000515683.4 | chr4_99345202_- | -498.20 | -497.40 | -497.20 |
CAediting_377674 | ENST00000515683.4 | chr4_99345205_- | -497.40 | -497.40 | -497.20 |
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Relation with ADAR for ADH1C |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for ADH1C |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for ADH1C |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for ADH1C |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
ADH1C | P00326 | DB02659 | Cholic Acid | Alcohol dehydrogenase 1C | SmallMoleculeDrug | approved |
ADH1C | P00326 | DB00157 | NADH | Alcohol dehydrogenase 1C | SmallMoleculeDrug | approved|nutraceutical |
ADH1C | P00326 | DB01213 | Fomepizole | Alcohol dehydrogenase 1C | SmallMoleculeDrug | approved|vet_approved |
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RelatedDiseases for ADH1C |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
ADH1C | C0001973 | Alcoholic Intoxication, Chronic | 6 | CTD_human;PSYGENET |
ADH1C | C0001969 | Alcoholic Intoxication | 5 | PSYGENET |
ADH1C | C0085762 | Alcohol abuse | 5 | CTD_human;PSYGENET |
ADH1C | C0001956 | Alcohol Use Disorder | 1 | CTD_human |
ADH1C | C0026640 | Mouth Neoplasms | 1 | CTD_human |
ADH1C | C0153381 | Malignant neoplasm of mouth | 1 | CTD_human |