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Editing gene: EFCAB13 (CAeditome ID:124989)

Gene summary for EFCAB13

Gene summary

Gene information	Gene symbol	EFCAB13
	Gene ID	124989
	Gene name	EF-hand calcium binding domain 13
	Synonyms	C17orf57
	Cytomap	17q21.32
	Type of gene	protein-coding
	Description	EF-hand calcium-binding domain-containing protein 13EF-hand domain-containing protein C17orf57
	Modification date	20210518
	UniProtAcc	Q8IY85
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for EFCAB13

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000178852.14

RNA A-to-I editing events in Cancer.

CAediting_1207647(47325100, +), CAediting_1207648(47325138, +), CAediting_1207649(47325307, +), CAediting_1207650(47327193, +), CAediting_1207651(47327240, +), CAediting_1207652(47327245, +), CAediting_1207653(47327269, +), CAediting_1207654(47327282, +), CAediting_1207655(47327304, +), CAediting_1207656(47327425, +), CAediting_1207657(47327437, +), CAediting_1207658(47327508, +), CAediting_1207659(47327532, +), CAediting_1207660(47327537, +), CAediting_1207661(47327551, +), CAediting_1207662(47327572, +), CAediting_1207663(47327584, +), CAediting_1207664(47327594, +), CAediting_1207665(47327616, +), CAediting_1207666(47327617, +), CAediting_1207667(47327620, +), CAediting_1207668(47327621, +), CAediting_1207669(47327631, +), CAediting_1207670(47327640, +), CAediting_1207671(47327657, +), CAediting_1207672(47327659, +), CAediting_1207673(47327677, +), CAediting_1207674(47327729, +), CAediting_1207675(47338319, +), CAediting_1207676(47340700, +), CAediting_1207677(47340863, +), CAediting_1207678(47347009, +), CAediting_1207679(47347012, +), CAediting_1207680(47347057, +), CAediting_1207681(47347077, +), CAediting_1207682(47347088, +), CAediting_1207683(47347120, +), CAediting_1207684(47347146, +), CAediting_1207685(47347156, +), CAediting_1207686(47347173, +), CAediting_1207687(47359197, +), CAediting_1207688(47359223, +), CAediting_1207689(47363158, +), CAediting_1207690(47364414, +), CAediting_1207691(47381113, +), CAediting_1207692(47381129, +), CAediting_1207693(47406309, +), CAediting_1207694(47408489, +), CAediting_1207695(47408577, +), CAediting_1207696(47432047, +), CAediting_1207697(47432060, +), CAediting_1207698(47432147, +), CAediting_1207699(47434097, +), CAediting_1207700(47434136, +), CAediting_1207701(47434144, +), CAediting_1207702(47434162, +), CAediting_1207703(47434176, +), CAediting_1207704(47434183, +), CAediting_1207705(47434193, +), CAediting_1207706(47434194, +), CAediting_1207707(47434213, +), CAediting_1207708(47434218, +), CAediting_1207709(47434221, +), CAediting_1207710(47434222, +), CAediting_1207711(47434236, +), CAediting_1207712(47434237, +), CAediting_1207713(47434252, +), CAediting_1207714(47434275, +), CAediting_1207715(47434277, +), CAediting_1207716(47434286, +), CAediting_1207717(47434287, +), CAediting_1207718(47434294, +), CAediting_1207719(47434338, +), CAediting_1207720(47435590, +), CAediting_1207721(47435614, +), CAediting_1207722(47435620, +), CAediting_1207723(47435632, +), CAediting_1207724(47435637, +), CAediting_1207725(47435638, +), CAediting_1207726(47435645, +), CAediting_1207727(47435652, +), CAediting_1207728(47435679, +), CAediting_1207729(47435702, +), CAediting_1207730(47439238, +), CAediting_1207731(47439240, +), CAediting_1207732(47439277, +), CAediting_1207733(47439294, +), CAediting_1207734(47439351, +), CAediting_1207735(47439360, +), CAediting_1207736(47439374, +), CAediting_1207737(47439377, +), CAediting_1207738(47439429, +), CAediting_1207739(47439446, +), CAediting_1207740(47439451, +),

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RNA editing positional annotations for EFCAB13 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1207647	chr17_47325100_+	ncRNA_intronic
CAediting_1207648	chr17_47325138_+	ncRNA_intronic
CAediting_1207649	chr17_47325307_+	ncRNA_intronic
CAediting_1207650	chr17_47327193_+	ncRNA_intronic
CAediting_1207651	chr17_47327240_+	ncRNA_intronic
CAediting_1207652	chr17_47327245_+	ncRNA_intronic
CAediting_1207653	chr17_47327269_+	ncRNA_intronic
CAediting_1207654	chr17_47327282_+	ncRNA_intronic
CAediting_1207655	chr17_47327304_+	ncRNA_intronic
CAediting_1207656	chr17_47327425_+	ncRNA_intronic
CAediting_1207657	chr17_47327437_+	ncRNA_intronic
CAediting_1207658	chr17_47327508_+	ncRNA_intronic
CAediting_1207659	chr17_47327532_+	ncRNA_intronic
CAediting_1207660	chr17_47327537_+	ncRNA_intronic
CAediting_1207661	chr17_47327551_+	ncRNA_intronic
CAediting_1207662	chr17_47327572_+	ncRNA_intronic
CAediting_1207663	chr17_47327584_+	ncRNA_intronic
CAediting_1207664	chr17_47327594_+	ncRNA_intronic
CAediting_1207665	chr17_47327616_+	ncRNA_intronic
CAediting_1207666	chr17_47327617_+	ncRNA_intronic
CAediting_1207667	chr17_47327620_+	ncRNA_intronic
CAediting_1207668	chr17_47327621_+	ncRNA_intronic
CAediting_1207669	chr17_47327631_+	ncRNA_intronic
CAediting_1207670	chr17_47327640_+	ncRNA_intronic
CAediting_1207671	chr17_47327657_+	ncRNA_intronic
CAediting_1207672	chr17_47327659_+	ncRNA_intronic
CAediting_1207673	chr17_47327677_+	ncRNA_intronic
CAediting_1207674	chr17_47327729_+	ncRNA_intronic
CAediting_1207675	chr17_47338319_+	ncRNA_intronic
CAediting_1207676	chr17_47340700_+	ncRNA_intronic
CAediting_1207677	chr17_47340863_+	ncRNA_intronic
CAediting_1207678	chr17_47347009_+	ncRNA_intronic
CAediting_1207679	chr17_47347012_+	ncRNA_intronic
CAediting_1207680	chr17_47347057_+	ncRNA_intronic
CAediting_1207681	chr17_47347077_+	ncRNA_intronic
CAediting_1207682	chr17_47347088_+	ncRNA_intronic
CAediting_1207683	chr17_47347120_+	ncRNA_intronic
CAediting_1207684	chr17_47347146_+	ncRNA_intronic
CAediting_1207685	chr17_47347156_+	ncRNA_intronic
CAediting_1207686	chr17_47347173_+	ncRNA_intronic
CAediting_1207687	chr17_47359197_+	ncRNA_intronic
CAediting_1207688	chr17_47359223_+	ncRNA_intronic
CAediting_1207689	chr17_47363158_+	ncRNA_intronic
CAediting_1207690	chr17_47364414_+	ncRNA_intronic
CAediting_1207691	chr17_47381113_+	ncRNA_intronic
CAediting_1207692	chr17_47381129_+	ncRNA_intronic
CAediting_1207693	chr17_47406309_+	intronic
CAediting_1207694	chr17_47408489_+	intronic
CAediting_1207695	chr17_47408577_+	intronic
CAediting_1207696	chr17_47432047_+	intronic
CAediting_1207697	chr17_47432060_+	intronic
CAediting_1207698	chr17_47432147_+	intronic
CAediting_1207699	chr17_47434097_+	intronic
CAediting_1207700	chr17_47434136_+	intronic
CAediting_1207701	chr17_47434144_+	intronic
CAediting_1207702	chr17_47434162_+	intronic
CAediting_1207703	chr17_47434176_+	intronic
CAediting_1207704	chr17_47434183_+	intronic
CAediting_1207705	chr17_47434193_+	intronic
CAediting_1207706	chr17_47434194_+	intronic
CAediting_1207707	chr17_47434213_+	intronic
CAediting_1207708	chr17_47434218_+	intronic
CAediting_1207709	chr17_47434221_+	intronic
CAediting_1207710	chr17_47434222_+	intronic
CAediting_1207711	chr17_47434236_+	intronic
CAediting_1207712	chr17_47434237_+	intronic
CAediting_1207713	chr17_47434252_+	intronic
CAediting_1207714	chr17_47434275_+	intronic
CAediting_1207715	chr17_47434277_+	intronic
CAediting_1207716	chr17_47434286_+	intronic
CAediting_1207717	chr17_47434287_+	intronic
CAediting_1207718	chr17_47434294_+	intronic
CAediting_1207719	chr17_47434338_+	intronic
CAediting_1207720	chr17_47435590_+	intronic
CAediting_1207721	chr17_47435614_+	intronic
CAediting_1207722	chr17_47435620_+	intronic
CAediting_1207723	chr17_47435632_+	intronic
CAediting_1207724	chr17_47435637_+	intronic
CAediting_1207725	chr17_47435638_+	intronic
CAediting_1207726	chr17_47435645_+	intronic
CAediting_1207727	chr17_47435652_+	intronic
CAediting_1207728	chr17_47435679_+	intronic
CAediting_1207729	chr17_47435702_+	intronic
CAediting_1207730	chr17_47439238_+	intronic
CAediting_1207731	chr17_47439240_+	intronic
CAediting_1207732	chr17_47439277_+	intronic
CAediting_1207733	chr17_47439294_+	intronic
CAediting_1207734	chr17_47439351_+	intronic
CAediting_1207735	chr17_47439360_+	intronic
CAediting_1207736	chr17_47439374_+	intronic
CAediting_1207737	chr17_47439377_+	intronic
CAediting_1207738	chr17_47439429_+	intronic
CAediting_1207739	chr17_47439446_+	intronic
CAediting_1207740	chr17_47439451_+	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1207647	chr17_47325100_+	SINE	Alu	AluJr
CAediting_1207648	chr17_47325138_+	SINE	Alu	AluJr
CAediting_1207649	chr17_47325307_+	SINE	Alu	AluJr
CAediting_1207650	chr17_47327193_+	SINE	Alu	AluSg7
CAediting_1207651	chr17_47327240_+	SINE	Alu	AluSg7
CAediting_1207652	chr17_47327245_+	SINE	Alu	AluSg7
CAediting_1207653	chr17_47327269_+	SINE	Alu	AluSg7
CAediting_1207654	chr17_47327282_+	SINE	Alu	AluSg7
CAediting_1207655	chr17_47327304_+	SINE	Alu	AluSg7
CAediting_1207656	chr17_47327425_+	SINE	Alu	AluSg7
CAediting_1207657	chr17_47327437_+	SINE	Alu	AluSg7
CAediting_1207658	chr17_47327508_+	SINE	Alu	AluSc
CAediting_1207659	chr17_47327532_+	SINE	Alu	AluSc
CAediting_1207660	chr17_47327537_+	SINE	Alu	AluSc
CAediting_1207661	chr17_47327551_+	SINE	Alu	AluSc
CAediting_1207662	chr17_47327572_+	SINE	Alu	AluSc
CAediting_1207663	chr17_47327584_+	SINE	Alu	AluSc
CAediting_1207664	chr17_47327594_+	SINE	Alu	AluSc
CAediting_1207665	chr17_47327616_+	SINE	Alu	AluSc
CAediting_1207666	chr17_47327617_+	SINE	Alu	AluSc
CAediting_1207667	chr17_47327620_+	SINE	Alu	AluSc
CAediting_1207668	chr17_47327621_+	SINE	Alu	AluSc
CAediting_1207669	chr17_47327631_+	SINE	Alu	AluSc
CAediting_1207670	chr17_47327640_+	SINE	Alu	AluSc
CAediting_1207671	chr17_47327657_+	SINE	Alu	AluSc
CAediting_1207672	chr17_47327659_+	SINE	Alu	AluSc
CAediting_1207673	chr17_47327677_+	SINE	Alu	AluSc
CAediting_1207674	chr17_47327729_+	SINE	Alu	AluSc
CAediting_1207675	chr17_47338319_+	SINE	Alu	AluJr4
CAediting_1207676	chr17_47340700_+	SINE	Alu	AluSx
CAediting_1207677	chr17_47340863_+	SINE	Alu	AluSx
CAediting_1207678	chr17_47347009_+	SINE	Alu	AluJo
CAediting_1207679	chr17_47347012_+	SINE	Alu	AluJo
CAediting_1207680	chr17_47347057_+	SINE	Alu	AluJo
CAediting_1207681	chr17_47347077_+	SINE	Alu	AluJo
CAediting_1207682	chr17_47347088_+	SINE	Alu	AluJo
CAediting_1207683	chr17_47347120_+	SINE	Alu	AluJo
CAediting_1207684	chr17_47347146_+	SINE	Alu	AluJo
CAediting_1207685	chr17_47347156_+	SINE	Alu	AluJo
CAediting_1207686	chr17_47347173_+	SINE	Alu	AluJo
CAediting_1207687	chr17_47359197_+	SINE	Alu	AluJb
CAediting_1207688	chr17_47359223_+	SINE	Alu	AluJb
CAediting_1207689	chr17_47363158_+	SINE	Alu	AluJr4
CAediting_1207690	chr17_47364414_+	SINE	Alu	AluSc5
CAediting_1207691	chr17_47381113_+	SINE	Alu	AluSc8
CAediting_1207692	chr17_47381129_+	SINE	Alu	AluSc8
CAediting_1207693	chr17_47406309_+	SINE	Alu	AluSg
CAediting_1207694	chr17_47408489_+	SINE	Alu	AluSx
CAediting_1207695	chr17_47408577_+	SINE	Alu	AluSx
CAediting_1207696	chr17_47432047_+	SINE	Alu	AluJb
CAediting_1207697	chr17_47432060_+	SINE	Alu	AluJb
CAediting_1207698	chr17_47432147_+	SINE	Alu	AluY
CAediting_1207699	chr17_47434097_+	LINE	L1	L1PB
CAediting_1207700	chr17_47434136_+	LINE	L1	L1PB
CAediting_1207701	chr17_47434144_+	LINE	L1	L1PB
CAediting_1207702	chr17_47434162_+	LINE	L1	L1PB
CAediting_1207703	chr17_47434176_+	LINE	L1	L1PB
CAediting_1207704	chr17_47434183_+	LINE	L1	L1PB
CAediting_1207705	chr17_47434193_+	LINE	L1	L1PB
CAediting_1207706	chr17_47434194_+	LINE	L1	L1PB
CAediting_1207707	chr17_47434213_+	LINE	L1	L1PB
CAediting_1207708	chr17_47434218_+	LINE	L1	L1PB
CAediting_1207709	chr17_47434221_+	LINE	L1	L1PB
CAediting_1207710	chr17_47434222_+	LINE	L1	L1PB
CAediting_1207711	chr17_47434236_+	LINE	L1	L1PB
CAediting_1207712	chr17_47434237_+	LINE	L1	L1PB
CAediting_1207713	chr17_47434252_+	LINE	L1	L1PB
CAediting_1207714	chr17_47434275_+	LINE	L1	L1PB
CAediting_1207715	chr17_47434277_+	LINE	L1	L1PB
CAediting_1207716	chr17_47434286_+	LINE	L1	L1PB
CAediting_1207717	chr17_47434287_+	LINE	L1	L1PB
CAediting_1207718	chr17_47434294_+	LINE	L1	L1PB
CAediting_1207719	chr17_47434338_+	LINE	L1	L1PB
CAediting_1207720	chr17_47435590_+	LINE	L1	L1PBa
CAediting_1207721	chr17_47435614_+	LINE	L1	L1PBa
CAediting_1207722	chr17_47435620_+	LINE	L1	L1PBa
CAediting_1207723	chr17_47435632_+	LINE	L1	L1PBa
CAediting_1207724	chr17_47435637_+	LINE	L1	L1PBa
CAediting_1207725	chr17_47435638_+	LINE	L1	L1PBa
CAediting_1207726	chr17_47435645_+	LINE	L1	L1PBa
CAediting_1207727	chr17_47435652_+	LINE	L1	L1PBa
CAediting_1207728	chr17_47435679_+	LINE	L1	L1PBa
CAediting_1207729	chr17_47435702_+	LINE	L1	L1PBa
CAediting_1207730	chr17_47439238_+	SINE	Alu	AluSx1
CAediting_1207731	chr17_47439240_+	SINE	Alu	AluSx1
CAediting_1207732	chr17_47439277_+	SINE	Alu	AluSx1
CAediting_1207733	chr17_47439294_+	SINE	Alu	AluSx1
CAediting_1207734	chr17_47439351_+	SINE	Alu	AluSx1
CAediting_1207735	chr17_47439360_+	SINE	Alu	AluSx1
CAediting_1207736	chr17_47439374_+	SINE	Alu	AluSx1
CAediting_1207737	chr17_47439377_+	SINE	Alu	AluSx1
CAediting_1207738	chr17_47439429_+	SINE	Alu	AluSx1
CAediting_1207739	chr17_47439446_+	SINE	Alu	AluSx1
CAediting_1207740	chr17_47439451_+	SINE	Alu	AluSx1

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RNA A-to-I editing events in the alternative splicing sites for EFCAB13

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000178852.14.EFCAB13.

Correlation between RNA A-to-I editing and PSI for ENSG00000178852.14.EFCAB13.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for EFCAB13

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for EFCAB13

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for EFCAB13

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1229415	chr17_67471547_+	ENSG00000178852.14	ENST00000517484	hsa-miR-548aa	47430283	47430289	7mer-m8	47430265	47430290	154	-14.23

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for EFCAB13

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for EFCAB13

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for EFCAB13

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for EFCAB13

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for EFCAB13

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for EFCAB13

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene