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Editing gene: CCR4 (CAeditome ID:1233)

Gene summary for CCR4

Gene summary

Gene information	Gene symbol	CCR4
	Gene ID	1233
	Gene name	C-C motif chemokine receptor 4
	Synonyms	CC-CKR-4\|CD194\|CKR4\|CMKBR4\|ChemR13\|HGCN:14099\|K5-5
	Cytomap	3p22.3
	Type of gene	protein-coding
	Description	C-C chemokine receptor type 4C-C CKR-4CCR-4chemokine (C-C motif) receptor 4chemokine (C-C) receptor 4
	Modification date	20210518
	UniProtAcc	P51679
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
CCR4	GO:0005886	C-C chemokine receptor type 4	0000052

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RNA A-to-I events for CCR4

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000183813.6

RNA A-to-I editing events in Cancer.

CAediting_265204(32953475, +), CAediting_265205(32955281, +), CAediting_265206(32955282, +), CAediting_265207(32955287, +), CAediting_265208(32955304, +), CAediting_265209(32955317, +), CAediting_265210(32955322, +), CAediting_265211(32955341, +), CAediting_265212(32955350, +), CAediting_265213(32955351, +), CAediting_265214(32955372, +), CAediting_265215(32955375, +), CAediting_265216(32955380, +), CAediting_265217(32955382, +), CAediting_265218(32955390, +), CAediting_265219(32955394, +), CAediting_265220(32955416, +), CAediting_265221(32955417, +), CAediting_265222(32955422, +), CAediting_265223(32955426, +), CAediting_265224(32955451, +), CAediting_265225(32955487, +), CAediting_265226(32955489, +), CAediting_265227(32955497, +), CAediting_265228(32955547, +), CAediting_265229(32955636, +), CAediting_265230(32955660, +), CAediting_265231(32955674, +), CAediting_265232(32955690, +), CAediting_265233(32955714, +), CAediting_265234(32955727, +), CAediting_265235(32955735, +), CAediting_265236(32955736, +), CAediting_265237(32955739, +), CAediting_265238(32955749, +), CAediting_265239(32955751, +), CAediting_265240(32955755, +), CAediting_265241(32955791, +), CAediting_265242(32955794, +), CAediting_265243(32955796, +), CAediting_265244(32955808, +), CAediting_265245(32955816, +), CAediting_265246(32955819, +), CAediting_265247(32955820, +), CAediting_265248(32955870, +), CAediting_265249(32955883, +), CAediting_265250(32955929, +), CAediting_265251(32955952, +), CAediting_265252(32955971, +), CAediting_265253(32956016, +), CAediting_265254(32956023, +), CAediting_265255(32956040, +), CAediting_265256(32956048, +), CAediting_265257(32956049, +), CAediting_265258(32956052, +), CAediting_265259(32956062, +), CAediting_265260(32956064, +), CAediting_265261(32956088, +), CAediting_265262(32956089, +), CAediting_265263(32956103, +), CAediting_265264(32956106, +), CAediting_265265(32956120, +), CAediting_265266(32956125, +), CAediting_265267(32956132, +), CAediting_265268(32956197, +),

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RNA editing positional annotations for CCR4 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_265204	chr3_32953475_+	exonic
CAediting_265205	chr3_32955281_+	UTR3
CAediting_265206	chr3_32955282_+	UTR3
CAediting_265207	chr3_32955287_+	UTR3
CAediting_265208	chr3_32955304_+	UTR3
CAediting_265209	chr3_32955317_+	UTR3
CAediting_265210	chr3_32955322_+	UTR3
CAediting_265211	chr3_32955341_+	UTR3
CAediting_265212	chr3_32955350_+	UTR3
CAediting_265213	chr3_32955351_+	UTR3
CAediting_265214	chr3_32955372_+	UTR3
CAediting_265215	chr3_32955375_+	UTR3
CAediting_265216	chr3_32955380_+	UTR3
CAediting_265217	chr3_32955382_+	UTR3
CAediting_265218	chr3_32955390_+	UTR3
CAediting_265219	chr3_32955394_+	UTR3
CAediting_265220	chr3_32955416_+	UTR3
CAediting_265221	chr3_32955417_+	UTR3
CAediting_265222	chr3_32955422_+	UTR3
CAediting_265223	chr3_32955426_+	UTR3
CAediting_265224	chr3_32955451_+	UTR3
CAediting_265225	chr3_32955487_+	UTR3
CAediting_265226	chr3_32955489_+	UTR3
CAediting_265227	chr3_32955497_+	UTR3
CAediting_265228	chr3_32955547_+	UTR3
CAediting_265229	chr3_32955636_+	UTR3
CAediting_265230	chr3_32955660_+	UTR3
CAediting_265231	chr3_32955674_+	UTR3
CAediting_265232	chr3_32955690_+	UTR3
CAediting_265233	chr3_32955714_+	UTR3
CAediting_265234	chr3_32955727_+	UTR3
CAediting_265235	chr3_32955735_+	UTR3
CAediting_265236	chr3_32955736_+	UTR3
CAediting_265237	chr3_32955739_+	UTR3
CAediting_265238	chr3_32955749_+	UTR3
CAediting_265239	chr3_32955751_+	UTR3
CAediting_265240	chr3_32955755_+	UTR3
CAediting_265241	chr3_32955791_+	UTR3
CAediting_265242	chr3_32955794_+	UTR3
CAediting_265243	chr3_32955796_+	UTR3
CAediting_265244	chr3_32955808_+	UTR3
CAediting_265245	chr3_32955816_+	UTR3
CAediting_265246	chr3_32955819_+	UTR3
CAediting_265247	chr3_32955820_+	UTR3
CAediting_265248	chr3_32955870_+	UTR3
CAediting_265249	chr3_32955883_+	UTR3
CAediting_265250	chr3_32955929_+	UTR3
CAediting_265251	chr3_32955952_+	UTR3
CAediting_265252	chr3_32955971_+	UTR3
CAediting_265253	chr3_32956016_+	UTR3
CAediting_265254	chr3_32956023_+	UTR3
CAediting_265255	chr3_32956040_+	UTR3
CAediting_265256	chr3_32956048_+	UTR3
CAediting_265257	chr3_32956049_+	UTR3
CAediting_265258	chr3_32956052_+	UTR3
CAediting_265259	chr3_32956062_+	UTR3
CAediting_265260	chr3_32956064_+	UTR3
CAediting_265261	chr3_32956088_+	UTR3
CAediting_265262	chr3_32956089_+	UTR3
CAediting_265263	chr3_32956103_+	UTR3
CAediting_265264	chr3_32956106_+	UTR3
CAediting_265265	chr3_32956120_+	UTR3
CAediting_265266	chr3_32956125_+	UTR3
CAediting_265267	chr3_32956132_+	UTR3
CAediting_265268	chr3_32956197_+	UTR3

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_265205	chr3_32955281_+	SINE	Alu	AluSp
CAediting_265206	chr3_32955282_+	SINE	Alu	AluSp
CAediting_265207	chr3_32955287_+	SINE	Alu	AluSp
CAediting_265208	chr3_32955304_+	SINE	Alu	AluSp
CAediting_265209	chr3_32955317_+	SINE	Alu	AluSp
CAediting_265210	chr3_32955322_+	SINE	Alu	AluSp
CAediting_265211	chr3_32955341_+	SINE	Alu	AluSp
CAediting_265212	chr3_32955350_+	SINE	Alu	AluSp
CAediting_265213	chr3_32955351_+	SINE	Alu	AluSp
CAediting_265214	chr3_32955372_+	SINE	Alu	AluSp
CAediting_265215	chr3_32955375_+	SINE	Alu	AluSp
CAediting_265216	chr3_32955380_+	SINE	Alu	AluSp
CAediting_265217	chr3_32955382_+	SINE	Alu	AluSp
CAediting_265218	chr3_32955390_+	SINE	Alu	AluSp
CAediting_265219	chr3_32955394_+	SINE	Alu	AluSp
CAediting_265220	chr3_32955416_+	SINE	Alu	AluSp
CAediting_265221	chr3_32955417_+	SINE	Alu	AluSp
CAediting_265222	chr3_32955422_+	SINE	Alu	AluSp
CAediting_265223	chr3_32955426_+	SINE	Alu	AluSp
CAediting_265224	chr3_32955451_+	SINE	Alu	AluSp
CAediting_265225	chr3_32955487_+	SINE	Alu	AluSp
CAediting_265226	chr3_32955489_+	SINE	Alu	AluSp
CAediting_265227	chr3_32955497_+	SINE	Alu	AluSp
CAediting_265228	chr3_32955547_+	SINE	Alu	AluSp
CAediting_265229	chr3_32955636_+	SINE	Alu	AluY
CAediting_265230	chr3_32955660_+	SINE	Alu	AluY
CAediting_265231	chr3_32955674_+	SINE	Alu	AluY
CAediting_265232	chr3_32955690_+	SINE	Alu	AluY
CAediting_265233	chr3_32955714_+	SINE	Alu	AluY
CAediting_265234	chr3_32955727_+	SINE	Alu	AluY
CAediting_265235	chr3_32955735_+	SINE	Alu	AluY
CAediting_265236	chr3_32955736_+	SINE	Alu	AluY
CAediting_265237	chr3_32955739_+	SINE	Alu	AluY
CAediting_265238	chr3_32955749_+	SINE	Alu	AluY
CAediting_265239	chr3_32955751_+	SINE	Alu	AluY
CAediting_265240	chr3_32955755_+	SINE	Alu	AluY
CAediting_265241	chr3_32955791_+	SINE	Alu	AluY
CAediting_265242	chr3_32955794_+	SINE	Alu	AluY
CAediting_265243	chr3_32955796_+	SINE	Alu	AluY
CAediting_265244	chr3_32955808_+	SINE	Alu	AluY
CAediting_265245	chr3_32955816_+	SINE	Alu	AluY
CAediting_265246	chr3_32955819_+	SINE	Alu	AluY
CAediting_265247	chr3_32955820_+	SINE	Alu	AluY
CAediting_265248	chr3_32955870_+	SINE	Alu	AluY
CAediting_265249	chr3_32955883_+	SINE	Alu	AluY
CAediting_265250	chr3_32955929_+	SINE	Alu	AluSx
CAediting_265251	chr3_32955952_+	SINE	Alu	AluSx
CAediting_265252	chr3_32955971_+	SINE	Alu	AluSx
CAediting_265253	chr3_32956016_+	SINE	Alu	AluSx
CAediting_265254	chr3_32956023_+	SINE	Alu	AluSx
CAediting_265255	chr3_32956040_+	SINE	Alu	AluSx
CAediting_265256	chr3_32956048_+	SINE	Alu	AluSx
CAediting_265257	chr3_32956049_+	SINE	Alu	AluSx
CAediting_265258	chr3_32956052_+	SINE	Alu	AluSx
CAediting_265259	chr3_32956062_+	SINE	Alu	AluSx
CAediting_265260	chr3_32956064_+	SINE	Alu	AluSx
CAediting_265261	chr3_32956088_+	SINE	Alu	AluSx
CAediting_265262	chr3_32956089_+	SINE	Alu	AluSx
CAediting_265263	chr3_32956103_+	SINE	Alu	AluSx
CAediting_265264	chr3_32956106_+	SINE	Alu	AluSx
CAediting_265265	chr3_32956120_+	SINE	Alu	AluSx
CAediting_265266	chr3_32956125_+	SINE	Alu	AluSx
CAediting_265267	chr3_32956132_+	SINE	Alu	AluSx
CAediting_265268	chr3_32956197_+	SINE	Alu	AluSx

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RNA A-to-I editing events in the alternative splicing sites for CCR4

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000183813.6.CCR4.

Correlation between RNA A-to-I editing and PSI for ENSG00000183813.6.CCR4.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CCR4

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for CCR4

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for CCR4

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_265205	chr3_32955281_+	ENSG00000183813.6	ENST00000330953	hsa-miR-513a-5p	32955275	32955281	7mer-m8	32955265	32955282	143.00	-16.23
CAediting_265205	chr3_32955281_+	ENSG00000183813.6	ENST00000330953	hsa-miR-513a-5p	32955275	32955281	7mer-m8	32955265	32955282	143.00	-16.23
CAediting_265205	chr3_32955281_+	ENSG00000183813.6	ENST00000330953	hsa-miR-638	32955280	32955286	7mer-1a	32955259	32955286	149.00	-37.65
CAediting_265206	chr3_32955282_+	ENSG00000183813.6	ENST00000330953	hsa-miR-139-5p	32955276	32955281	6mer	32955275	32955296	143.00	-20.23
CAediting_265214	chr3_32955372_+	ENSG00000183813.6	ENST00000330953	hsa-miR-2467-3p	32955367	32955372	6mer	32955352	32955373	147.00	-24.97
CAediting_265214	chr3_32955372_+	ENSG00000183813.6	ENST00000330953	hsa-miR-374b-3p	32955369	32955376	8mer-1a	32955355	32955376	141.00	-8.66
CAediting_265215	chr3_32955375_+	ENSG00000183813.6	ENST00000330953	hsa-miR-222-5p	32955369	32955376	8mer-1a	32955353	32955376	147.00	-16.67
CAediting_265215	chr3_32955375_+	ENSG00000183813.6	ENST00000330953	hsa-miR-30a-3p	32955371	32955378	8mer-1a	32955353	32955378	147.00	-10.42
CAediting_265215	chr3_32955375_+	ENSG00000183813.6	ENST00000330953	hsa-miR-30d-3p	32955371	32955378	8mer-1a	32955354	32955378	150.00	-12.89
CAediting_265215	chr3_32955375_+	ENSG00000183813.6	ENST00000330953	hsa-miR-30e-3p	32955371	32955378	8mer-1a	32955353	32955378	147.00	-11.19
CAediting_265215	chr3_32955375_+	ENSG00000183813.6	ENST00000330953	hsa-miR-936	32955368	32955375	8mer-1a	32955354	32955375	158.00	-22.00
CAediting_265223	chr3_32955426_+	ENSG00000183813.6	ENST00000330953	hsa-miR-1207-3p	32955419	32955425	7mer-m8	32955409	32955426	140.00	-12.56
CAediting_265223	chr3_32955426_+	ENSG00000183813.6	ENST00000330953	hsa-miR-646	32955421	32955427	7mer-m8	32955410	32955428	145.00	-14.99
CAediting_265226	chr3_32955489_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6790-3p	32955484	32955490	7mer-m8	32955472	32955491	157.00	-27.59
CAediting_265232	chr3_32955690_+	ENSG00000183813.6	ENST00000330953	hsa-miR-17-3p	32955683	32955689	7mer-m8	32955669	32955690	150.00	-17.66
CAediting_265232	chr3_32955690_+	ENSG00000183813.6	ENST00000330953	hsa-miR-596	32955686	32955692	7mer-m8	32955673	32955693	140.00	-18.43
CAediting_265235	chr3_32955735_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6771-5p	32955729	32955735	7mer-m8	32955717	32955736	160.00	-34.33
CAediting_265236	chr3_32955736_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6852-5p	32955731	32955736	6mer	32955718	32955737	149.00	-26.62
CAediting_265237	chr3_32955739_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3614-5p	32955732	32955738	7mer-m8	32955716	32955739	152.00	-25.27
CAediting_265238	chr3_32955749_+	ENSG00000183813.6	ENST00000330953	hsa-miR-17-3p	32955745	32955751	7mer-m8	32955730	32955752	150.00	-21.07
CAediting_265242	chr3_32955794_+	ENSG00000183813.6	ENST00000330953	hsa-miR-181a-2-3p	32955788	32955795	8mer-1a	32955774	32955795	140.00	-11.24
CAediting_265242	chr3_32955794_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6509-3p	32955789	32955795	7mer-m8	32955775	32955796	155.00	-13.80
CAediting_265247	chr3_32955820_+	ENSG00000183813.6	ENST00000330953	hsa-miR-370-3p	32955815	32955820	6mer	32955797	32955821	150.00	-28.97
CAediting_265248	chr3_32955870_+	ENSG00000183813.6	ENST00000330953	hsa-miR-326	32955865	32955871	7mer-m8	32955853	32955872	140.00	-15.12
CAediting_265248	chr3_32955870_+	ENSG00000183813.6	ENST00000330953	hsa-miR-330-5p	32955865	32955871	7mer-m8	32955851	32955872	140.00	-21.22
CAediting_265248	chr3_32955870_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4314	32955864	32955870	7mer-m8	32955854	32955871	140.00	-21.17
CAediting_265248	chr3_32955870_+	ENSG00000183813.6	ENST00000330953	hsa-miR-514a-5p	32955866	32955872	7mer-m8	32955850	32955873	146.00	-20.07
CAediting_265248	chr3_32955870_+	ENSG00000183813.6	ENST00000330953	hsa-miR-514a-5p	32955866	32955872	7mer-m8	32955850	32955873	146.00	-20.07
CAediting_265248	chr3_32955870_+	ENSG00000183813.6	ENST00000330953	hsa-miR-514a-5p	32955866	32955872	7mer-m8	32955850	32955873	146.00	-20.07
CAediting_265252	chr3_32955971_+	ENSG00000183813.6	ENST00000330953	hsa-miR-661	32955966	32955972	7mer-m8	32955950	32955973	147.00	-18.48
CAediting_265252	chr3_32955971_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6742-3p	32955965	32955971	7mer-m8	32955953	32955972	140.00	-13.49
CAediting_265252	chr3_32955971_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6776-5p	32955964	32955970	7mer-m8	32955952	32955971	156.00	-24.54
CAediting_265252	chr3_32955971_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6849-3p	32955969	32955976	8mer-1a	32955955	32955976	152.00	-18.04
CAediting_265253	chr3_32956016_+	ENSG00000183813.6	ENST00000330953	hsa-miR-1247-3p	32956011	32956017	7mer-m8	32955998	32956018	150.00	-21.49
CAediting_265254	chr3_32956023_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6078	32956019	32956026	8mer-1a	32956008	32956026	149.00	-21.50
CAediting_265208	chr3_32955304_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3176	32955297	32955303	7mer-m8	32955286	32955304	141.00	-18.21
CAediting_265208	chr3_32955304_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3620-3p	32955301	32955307	7mer-m8	32955286	32955308	164.00	-28.04
CAediting_265208	chr3_32955304_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3922-3p	32955297	32955303	7mer-m8	32955283	32955304	141.00	-19.07
CAediting_265210	chr3_32955322_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4726-3p	32955316	32955322	7mer-m8	32955300	32955323	149.00	-26.72
CAediting_265213	chr3_32955351_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3190-5p	32955344	32955350	7mer-m8	32955332	32955351	154.00	-19.64
CAediting_265217	chr3_32955382_+	ENSG00000183813.6	ENST00000330953	hsa-miR-153-5p	32955375	32955381	7mer-m8	32955361	32955382	148.00	-9.17
CAediting_265217	chr3_32955382_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3680-3p	32955379	32955386	8mer-1a	32955364	32955386	140.00	-14.07
CAediting_265217	chr3_32955382_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3680-3p	32955379	32955386	8mer-1a	32955364	32955386	140.00	-14.07
CAediting_265218	chr3_32955390_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3190-5p	32955388	32955394	7mer-m8	32955376	32955395	147.00	-16.24
CAediting_265218	chr3_32955390_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4701-5p	32955388	32955393	6mer	32955386	32955408	143.00	-29.17
CAediting_265218	chr3_32955390_+	ENSG00000183813.6	ENST00000330953	hsa-miR-548s	32955387	32955393	7mer-m8	32955372	32955394	157.00	-11.45
CAediting_265219	chr3_32955394_+	ENSG00000183813.6	ENST00000330953	hsa-miR-941	32955390	32955396	7mer-m8	32955373	32955397	148.00	-23.98
CAediting_265219	chr3_32955394_+	ENSG00000183813.6	ENST00000330953	hsa-miR-941	32955390	32955396	7mer-m8	32955373	32955397	148.00	-23.98
CAediting_265219	chr3_32955394_+	ENSG00000183813.6	ENST00000330953	hsa-miR-941	32955390	32955396	7mer-m8	32955373	32955397	148.00	-23.98
CAediting_265219	chr3_32955394_+	ENSG00000183813.6	ENST00000330953	hsa-miR-941	32955390	32955396	7mer-m8	32955373	32955397	148.00	-23.98
CAediting_265219	chr3_32955394_+	ENSG00000183813.6	ENST00000330953	hsa-miR-941	32955390	32955396	7mer-m8	32955373	32955397	148.00	-23.98
CAediting_265220	chr3_32955416_+	ENSG00000183813.6	ENST00000330953	hsa-miR-513a-5p	32955410	32955416	7mer-m8	32955400	32955417	156.00	-21.01
CAediting_265220	chr3_32955416_+	ENSG00000183813.6	ENST00000330953	hsa-miR-513a-5p	32955410	32955416	7mer-m8	32955400	32955417	156.00	-21.01
CAediting_265220	chr3_32955416_+	ENSG00000183813.6	ENST00000330953	hsa-miR-638	32955415	32955421	7mer-1a	32955397	32955421	159.00	-35.15
CAediting_265221	chr3_32955417_+	ENSG00000183813.6	ENST00000330953	hsa-miR-8052	32955415	32955421	7mer-1a	32955403	32955421	143.00	-24.25
CAediting_265229	chr3_32955636_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4432	32955633	32955639	7mer-m8	32955618	32955640	146.00	-11.81
CAediting_265240	chr3_32955755_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6720-3p	32955749	32955755	7mer-m8	32955735	32955756	147.00	-17.11
CAediting_265249	chr3_32955883_+	ENSG00000183813.6	ENST00000330953	hsa-miR-106a-3p	32955879	32955884	6mer	32955864	32955885	141.00	-21.13
CAediting_265250	chr3_32955929_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4698	32955923	32955928	6mer	32955907	32955929	141.00	-9.67
CAediting_265260	chr3_32956064_+	ENSG00000183813.6	ENST00000330953	hsa-miR-5195-5p	32956060	32956066	7mer-m8	32956045	32956067	152.00	-19.63
CAediting_265261	chr3_32956088_+	ENSG00000183813.6	ENST00000330953	hsa-miR-34a-3p	32956084	32956090	7mer-m8	32956069	32956091	145.00	-10.10
CAediting_265262	chr3_32956089_+	ENSG00000183813.6	ENST00000330953	hsa-miR-548ae-3p	32956087	32956093	7mer-m8	32956074	32956094	141.00	-10.65
CAediting_265262	chr3_32956089_+	ENSG00000183813.6	ENST00000330953	hsa-miR-548ae-3p	32956087	32956093	7mer-m8	32956074	32956094	141.00	-10.65
CAediting_265262	chr3_32956089_+	ENSG00000183813.6	ENST00000330953	hsa-miR-548ah-3p	32956087	32956093	7mer-m8	32956073	32956094	141.00	-10.74
CAediting_265262	chr3_32956089_+	ENSG00000183813.6	ENST00000330953	hsa-miR-548aj-3p	32956087	32956093	7mer-m8	32956074	32956094	141.00	-8.54
CAediting_265262	chr3_32956089_+	ENSG00000183813.6	ENST00000330953	hsa-miR-548aj-3p	32956087	32956093	7mer-m8	32956074	32956094	141.00	-8.54
CAediting_265262	chr3_32956089_+	ENSG00000183813.6	ENST00000330953	hsa-miR-548am-3p	32956087	32956093	7mer-m8	32956073	32956094	141.00	-11.02
CAediting_265262	chr3_32956089_+	ENSG00000183813.6	ENST00000330953	hsa-miR-548aq-3p	32956087	32956093	7mer-m8	32956073	32956094	141.00	-10.74
CAediting_265262	chr3_32956089_+	ENSG00000183813.6	ENST00000330953	hsa-miR-548j-3p	32956087	32956093	7mer-m8	32956073	32956094	144.00	-11.31
CAediting_265262	chr3_32956089_+	ENSG00000183813.6	ENST00000330953	hsa-miR-548x-3p	32956087	32956093	7mer-m8	32956075	32956094	141.00	-8.54
CAediting_265262	chr3_32956089_+	ENSG00000183813.6	ENST00000330953	hsa-miR-548x-3p	32956087	32956093	7mer-m8	32956075	32956094	141.00	-8.54
CAediting_265262	chr3_32956089_+	ENSG00000183813.6	ENST00000330953	hsa-miR-7844-5p	32956085	32956091	7mer-m8	32956071	32956092	161.00	-22.71
CAediting_265265	chr3_32956120_+	ENSG00000183813.6	ENST00000330953	hsa-miR-8074	32956118	32956124	7mer-m8	32956103	32956125	162.00	-20.87
CAediting_265268	chr3_32956197_+	ENSG00000183813.6	ENST00000330953	hsa-miR-106a-3p	32956193	32956198	6mer	32956178	32956199	141.00	-21.13
CAediting_265207	chr3_32955287_+	ENSG00000183813.6	ENST00000330953	hsa-miR-371a-3p	32955285	32955291	7mer-m8	32955270	32955292	144.00	-15.93
CAediting_265257	chr3_32956049_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4251	32956042	32956048	7mer-m8	32956033	32956049	140.00	-17.35
CAediting_265257	chr3_32956049_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4324	32956043	32956049	7mer-m8	32956031	32956050	146.00	-11.36
CAediting_265257	chr3_32956049_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6882-3p	32956047	32956053	7mer-m8	32956031	32956054	140.00	-18.29
CAediting_265267	chr3_32956132_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3940-3p	32956129	32956136	8mer-1a	32956115	32956136	140.00	-18.25

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_265205	chr3_32955281_+	ENSG00000183813.6	ENST00000330953	hsa-miR-10399-5p	32955276	32955282	7mer-m8	32955259	32955283	152	-18.36
CAediting_265206	chr3_32955282_+	ENSG00000183813.6	ENST00000330953	hsa-miR-10399-5p	32955276	32955282	7mer-m8	32955259	32955283	152	-18.36
CAediting_265220	chr3_32955416_+	ENSG00000183813.6	ENST00000330953	hsa-miR-10399-5p	32955411	32955417	7mer-m8	32955397	32955418	148	-11.23
CAediting_265221	chr3_32955417_+	ENSG00000183813.6	ENST00000330953	hsa-miR-10399-5p	32955411	32955417	7mer-m8	32955397	32955418	148	-11.23
CAediting_265235	chr3_32955735_+	ENSG00000183813.6	ENST00000330953	hsa-miR-12126	32955731	32955738	8mer-1a	32955715	32955738	147	-13.23
CAediting_265236	chr3_32955736_+	ENSG00000183813.6	ENST00000330953	hsa-miR-12126	32955731	32955738	8mer-1a	32955715	32955738	147	-13.23
CAediting_265209	chr3_32955317_+	ENSG00000183813.6	ENST00000330953	hsa-miR-125a-3p	32955314	32955321	8mer-1a	32955300	32955321	140	-18.66
CAediting_265239	chr3_32955751_+	ENSG00000183813.6	ENST00000330953	hsa-miR-1271-3p	32955749	32955755	7mer-m8	32955737	32955756	154	-19.82
CAediting_265240	chr3_32955755_+	ENSG00000183813.6	ENST00000330953	hsa-miR-1271-3p	32955749	32955755	7mer-m8	32955737	32955756	154	-19.82
CAediting_265253	chr3_32956016_+	ENSG00000183813.6	ENST00000330953	hsa-miR-1273h-5p	32956009	32956015	7mer-m8	32955996	32956016	151	-29.88
CAediting_265238	chr3_32955749_+	ENSG00000183813.6	ENST00000330953	hsa-miR-20b-3p	32955745	32955751	7mer-m8	32955730	32955752	149	-19.01
CAediting_265239	chr3_32955751_+	ENSG00000183813.6	ENST00000330953	hsa-miR-20b-3p	32955745	32955751	7mer-m8	32955730	32955752	149	-19.01
CAediting_265218	chr3_32955390_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3064-5p	32955389	32955394	6mer	32955375	32955395	141	-16.79
CAediting_265219	chr3_32955394_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3064-5p	32955389	32955394	6mer	32955375	32955395	141	-16.79
CAediting_265235	chr3_32955735_+	ENSG00000183813.6	ENST00000330953	hsa-miR-30b-3p	32955728	32955735	8mer-1a	32955714	32955735	151	-15.38
CAediting_265245	chr3_32955816_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3143	32955810	32955815	6mer	32955791	32955816	146	-14.96
CAediting_265267	chr3_32956132_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3190-5p	32956126	32956132	7mer-m8	32956115	32956133	144	-16.24
CAediting_265211	chr3_32955341_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3663-5p	32955335	32955341	7mer-m8	32955323	32955342	148	-21.98
CAediting_265240	chr3_32955755_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3665	32955753	32955759	7mer-m8	32955743	32955760	145	-16.92
CAediting_265242	chr3_32955794_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3675-3p	32955792	32955798	7mer-m8	32955778	32955799	149	-15.24
CAediting_265243	chr3_32955796_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3675-3p	32955792	32955798	7mer-m8	32955778	32955799	149	-15.24
CAediting_265264	chr3_32956106_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3675-3p	32956104	32956110	7mer-m8	32956090	32956111	145	-12.58
CAediting_265235	chr3_32955735_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3689a-3p	32955728	32955735	8mer-1a	32955715	32955735	147	-18.72
CAediting_265253	chr3_32956016_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3689a-3p	32956009	32956015	7mer-m8	32955996	32956016	150	-21.22
CAediting_265235	chr3_32955735_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3689b-3p	32955728	32955735	8mer-1a	32955715	32955735	147	-17.55
CAediting_265235	chr3_32955735_+	ENSG00000183813.6	ENST00000330953	hsa-miR-3689c	32955728	32955735	8mer-1a	32955715	32955735	147	-17.55
CAediting_265232	chr3_32955690_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4327	32955685	32955691	7mer-m8	32955673	32955692	147	-17.64
CAediting_265212	chr3_32955350_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4435	32955343	32955350	8mer-1a	32955330	32955350	146	-18.85
CAediting_265212	chr3_32955350_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4435	32955343	32955350	8mer-1a	32955330	32955350	146	-18.85
CAediting_265252	chr3_32955971_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4453	32955967	32955973	7mer-m8	32955955	32955974	145	-13.57
CAediting_265234	chr3_32955727_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4478	32955724	32955730	7mer-m8	32955716	32955731	149	-25.05
CAediting_265266	chr3_32956125_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4517	32956121	32956126	6mer	32956104	32956127	152	-19.07
CAediting_265232	chr3_32955690_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4538	32955687	32955692	6mer	32955671	32955693	143	-27.8
CAediting_265238	chr3_32955749_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4540	32955743	32955748	6mer	32955728	32955749	144	-18.36
CAediting_265225	chr3_32955487_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4638-5p	32955481	32955488	8mer-1a	32955467	32955488	144	-20.6
CAediting_265234	chr3_32955727_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4649-3p	32955721	32955727	7mer-m8	32955708	32955728	140	-14.11
CAediting_265255	chr3_32956040_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4649-3p	32956034	32956040	7mer-m8	32956021	32956041	140	-14.11
CAediting_265213	chr3_32955351_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4716-5p	32955349	32955356	8mer-1a	32955335	32955356	140	-12.81
CAediting_265218	chr3_32955390_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4735-5p	32955384	32955390	7mer-m8	32955370	32955391	140	-5.48
CAediting_265212	chr3_32955350_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4781-3p	32955347	32955353	7mer-m8	32955336	32955354	144	-13.86
CAediting_265213	chr3_32955351_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4781-3p	32955347	32955353	7mer-m8	32955336	32955354	144	-13.86
CAediting_265233	chr3_32955714_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4790-3p	32955710	32955716	7mer-m8	32955699	32955717	143	-15.21
CAediting_265218	chr3_32955390_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4794	32955388	32955394	7mer-m8	32955374	32955395	140	-12.3
CAediting_265219	chr3_32955394_+	ENSG00000183813.6	ENST00000330953	hsa-miR-4794	32955388	32955394	7mer-m8	32955374	32955395	140	-12.3
CAediting_265253	chr3_32956016_+	ENSG00000183813.6	ENST00000330953	hsa-miR-490-3p	32956013	32956019	7mer-m8	32955997	32956020	150	-17.88
CAediting_265206	chr3_32955282_+	ENSG00000183813.6	ENST00000330953	hsa-miR-5089-5p	32955280	32955286	7mer-m8	32955267	32955287	146	-12.8
CAediting_265207	chr3_32955287_+	ENSG00000183813.6	ENST00000330953	hsa-miR-5089-5p	32955280	32955286	7mer-m8	32955267	32955287	146	-12.8
CAediting_265221	chr3_32955417_+	ENSG00000183813.6	ENST00000330953	hsa-miR-5089-5p	32955415	32955421	7mer-m8	32955402	32955422	147	-14.68
CAediting_265222	chr3_32955422_+	ENSG00000183813.6	ENST00000330953	hsa-miR-5089-5p	32955415	32955421	7mer-m8	32955402	32955422	147	-14.68
CAediting_265207	chr3_32955287_+	ENSG00000183813.6	ENST00000330953	hsa-miR-512-3p	32955285	32955291	7mer-m8	32955271	32955292	149	-16.17
CAediting_265207	chr3_32955287_+	ENSG00000183813.6	ENST00000330953	hsa-miR-512-3p	32955285	32955291	7mer-m8	32955271	32955292	149	-16.17
CAediting_265267	chr3_32956132_+	ENSG00000183813.6	ENST00000330953	hsa-miR-548s	32956125	32956131	7mer-m8	32956111	32956132	143	-12.53
CAediting_265239	chr3_32955751_+	ENSG00000183813.6	ENST00000330953	hsa-miR-550a-3-5p	32955749	32955755	7mer-m8	32955737	32955756	143	-14.36
CAediting_265240	chr3_32955755_+	ENSG00000183813.6	ENST00000330953	hsa-miR-550a-3-5p	32955749	32955755	7mer-m8	32955737	32955756	143	-14.36
CAediting_265239	chr3_32955751_+	ENSG00000183813.6	ENST00000330953	hsa-miR-550a-5p	32955749	32955755	7mer-m8	32955734	32955756	143	-18.92
CAediting_265240	chr3_32955755_+	ENSG00000183813.6	ENST00000330953	hsa-miR-550a-5p	32955749	32955755	7mer-m8	32955734	32955756	143	-18.92
CAediting_265239	chr3_32955751_+	ENSG00000183813.6	ENST00000330953	hsa-miR-550a-5p	32955749	32955755	7mer-m8	32955734	32955756	143	-18.92
CAediting_265240	chr3_32955755_+	ENSG00000183813.6	ENST00000330953	hsa-miR-550a-5p	32955749	32955755	7mer-m8	32955734	32955756	143	-18.92
CAediting_265266	chr3_32956125_+	ENSG00000183813.6	ENST00000330953	hsa-miR-5583-3p	32956120	32956126	7mer-m8	32956106	32956127	143	-8.55
CAediting_265266	chr3_32956125_+	ENSG00000183813.6	ENST00000330953	hsa-miR-5583-3p	32956120	32956126	7mer-m8	32956106	32956127	143	-8.55
CAediting_265211	chr3_32955341_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6131	32955336	32955342	7mer-m8	32955325	32955343	140	-18.33
CAediting_265205	chr3_32955281_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6504-3p	32955276	32955282	7mer-m8	32955265	32955283	147	-12.35
CAediting_265206	chr3_32955282_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6504-3p	32955276	32955282	7mer-m8	32955265	32955283	147	-12.35
CAediting_265220	chr3_32955416_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6504-3p	32955411	32955417	7mer-m8	32955397	32955418	148	-15.29
CAediting_265221	chr3_32955417_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6504-3p	32955411	32955417	7mer-m8	32955397	32955418	148	-15.29
CAediting_265207	chr3_32955287_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6506-5p	32955281	32955287	7mer-m8	32955266	32955288	144	-21.76
CAediting_265222	chr3_32955422_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6506-5p	32955416	32955422	7mer-m8	32955402	32955423	147	-16.07
CAediting_265232	chr3_32955690_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6516-5p	32955683	32955689	7mer-m8	32955668	32955690	144	-17.11
CAediting_265227	chr3_32955497_+	ENSG00000183813.6	ENST00000330953	hsa-miR-652-3p	32955491	32955497	7mer-m8	32955477	32955498	154	-18.29
CAediting_265218	chr3_32955390_+	ENSG00000183813.6	ENST00000330953	hsa-miR-664a-5p	32955388	32955394	7mer-m8	32955372	32955395	141	-12.65
CAediting_265219	chr3_32955394_+	ENSG00000183813.6	ENST00000330953	hsa-miR-664a-5p	32955388	32955394	7mer-m8	32955372	32955395	141	-12.65
CAediting_265219	chr3_32955394_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6765-3p	32955391	32955397	7mer-m8	32955378	32955398	152	-20.77
CAediting_265234	chr3_32955727_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6765-5p	32955721	32955726	6mer	32955706	32955727	151	-30.57
CAediting_265235	chr3_32955735_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6779-5p	32955728	32955735	8mer-1a	32955717	32955735	148	-22.58
CAediting_265253	chr3_32956016_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6779-5p	32956009	32956015	7mer-m8	32955998	32956016	152	-23.72
CAediting_265235	chr3_32955735_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6780a-5p	32955728	32955735	8mer-1a	32955712	32955735	152	-25.37
CAediting_265253	chr3_32956016_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6780a-5p	32956009	32956015	7mer-m8	32955995	32956016	148	-25.5
CAediting_265210	chr3_32955322_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6790-3p	32955320	32955326	7mer-1a	32955304	32955326	141	-26.53
CAediting_265238	chr3_32955749_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6811-3p	32955748	32955754	7mer-1a	32955734	32955754	143	-20.33
CAediting_265239	chr3_32955751_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6811-3p	32955748	32955754	7mer-1a	32955734	32955754	143	-20.33
CAediting_265214	chr3_32955372_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6832-5p	32955366	32955372	7mer-m8	32955351	32955373	140	-18.87
CAediting_265211	chr3_32955341_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6843-3p	32955334	32955340	7mer-m8	32955322	32955341	152	-19.47
CAediting_265211	chr3_32955341_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6848-3p	32955334	32955340	7mer-m8	32955324	32955341	142	-14.3
CAediting_265223	chr3_32955426_+	ENSG00000183813.6	ENST00000330953	hsa-miR-6869-5p	32955423	32955429	7mer-m8	32955408	32955430	146	-19.73
CAediting_265205	chr3_32955281_+	ENSG00000183813.6	ENST00000330953	hsa-miR-7151-3p	32955274	32955281	8mer-1a	32955263	32955281	144	-18.24
CAediting_265220	chr3_32955416_+	ENSG00000183813.6	ENST00000330953	hsa-miR-7151-3p	32955409	32955416	8mer-1a	32955400	32955416	142	-15.31
CAediting_265234	chr3_32955727_+	ENSG00000183813.6	ENST00000330953	hsa-miR-7160-5p	32955722	32955728	7mer-m8	32955710	32955729	149	-18.69
CAediting_265255	chr3_32956040_+	ENSG00000183813.6	ENST00000330953	hsa-miR-7160-5p	32956035	32956041	7mer-m8	32956022	32956042	146	-20.9
CAediting_265240	chr3_32955755_+	ENSG00000183813.6	ENST00000330953	hsa-miR-764	32955752	32955758	7mer-m8	32955739	32955759	153	-25.2
CAediting_265230	chr3_32955660_+	ENSG00000183813.6	ENST00000330953	hsa-miR-7703	32955658	32955664	7mer-m8	32955643	32955665	154	-19.4
CAediting_265244	chr3_32955808_+	ENSG00000183813.6	ENST00000330953	hsa-miR-7855-5p	32955805	32955810	6mer	32955792	32955811	148	-26.03
CAediting_265265	chr3_32956120_+	ENSG00000183813.6	ENST00000330953	hsa-miR-7855-5p	32956117	32956122	6mer	32956104	32956123	148	-26.03
CAediting_265235	chr3_32955735_+	ENSG00000183813.6	ENST00000330953	hsa-miR-887-5p	32955729	32955735	7mer-m8	32955717	32955736	143	-19.73
CAediting_265236	chr3_32955736_+	ENSG00000183813.6	ENST00000330953	hsa-miR-887-5p	32955729	32955735	7mer-m8	32955717	32955736	143	-19.73
CAediting_265248	chr3_32955870_+	ENSG00000183813.6	ENST00000330953	hsa-miR-887-5p	32955863	32955870	8mer-1a	32955850	32955870	147	-13.82

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_980496	chr14_31014685_-	ENSG00000183813.6	ENST00000330953	hsa-miR-624-3p	32955360	32955366	7mer-m8	32955347	32955367	148	-12.36
CAediting_86358	chr1_109598906_+	ENSG00000183813.6	ENST00000330953	hsa-miR-197-5p	32955848	32955854	7mer-m8	32955830	32955855	158	-32.96
CAediting_228905	chr2_188297554_+	ENSG00000183813.6	ENST00000330953	hsa-miR-561-3p	32955525	32955531	7mer-m8	32955512	32955532	147	-13.47
CAediting_604450	chr7_133034877_-	ENSG00000183813.6	ENST00000330953	hsa-miR-3654	32954674	32954680	7mer-m8	32954663	32954681	144	-19.54
CAediting_524911	chr7_5495852_-	ENSG00000183813.6	ENST00000330953	hsa-miR-589-3p	32955639	32955645	7mer-m8	32955622	32955646	162	-19.59

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1160181	chr17_7017644_-	ENSG00000183813.6	ENST00000330953	hsa-miR-195-3p	32954790	32954796	7mer-m8	32954775	32954797	154	-11.69
CAediting_1229414	chr17_67471546_+	ENSG00000183813.6	ENST00000330953	hsa-miR-548aa	32955823	32955830	8mer-1a	32955806	32955830	148	-9.33
CAediting_228905	chr2_188297554_+	ENSG00000183813.6	ENST00000330953	hsa-miR-561-3p	32955076	32955082	7mer-m8	32955062	32955083	144	-3.31

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CCR4

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000330953.5	protein_coding

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_265204	ENST00000330953.5	chr3_32953475_+	-1188.20	-1188.20	-1222.30
CAediting_265205	ENST00000330953.5	chr3_32955281_+	-1188.30	-1188.20	-1222.30
CAediting_265206	ENST00000330953.5	chr3_32955282_+	-1188.20	-1188.20	-1222.30
CAediting_265207	ENST00000330953.5	chr3_32955287_+	-1187.50	-1188.20	-1222.30
CAediting_265208	ENST00000330953.5	chr3_32955304_+	-1187.70	-1188.20	-1222.30
CAediting_265209	ENST00000330953.5	chr3_32955317_+	-1187.80	-1188.20	-1222.30
CAediting_265210	ENST00000330953.5	chr3_32955322_+	-1187.30	-1188.20	-1222.30
CAediting_265211	ENST00000330953.5	chr3_32955341_+	-1188.20	-1188.20	-1222.30
CAediting_265212	ENST00000330953.5	chr3_32955350_+	-1187.90	-1188.20	-1222.30
CAediting_265213	ENST00000330953.5	chr3_32955351_+	-1187.90	-1188.20	-1222.30
CAediting_265214	ENST00000330953.5	chr3_32955372_+	-1188.20	-1188.20	-1222.30
CAediting_265215	ENST00000330953.5	chr3_32955375_+	-1188.30	-1188.20	-1222.30
CAediting_265216	ENST00000330953.5	chr3_32955380_+	-1188.20	-1188.20	-1222.30
CAediting_265217	ENST00000330953.5	chr3_32955382_+	-1188.20	-1188.20	-1222.30
CAediting_265218	ENST00000330953.5	chr3_32955390_+	-1187.90	-1188.20	-1222.30
CAediting_265219	ENST00000330953.5	chr3_32955394_+	-1188.60	-1188.20	-1222.30
CAediting_265220	ENST00000330953.5	chr3_32955416_+	-1188.30	-1188.20	-1222.30
CAediting_265221	ENST00000330953.5	chr3_32955417_+	-1193.10	-1188.20	-1222.30
CAediting_265222	ENST00000330953.5	chr3_32955422_+	-1187.50	-1188.20	-1222.30
CAediting_265223	ENST00000330953.5	chr3_32955426_+	-1192.40	-1188.20	-1222.30
CAediting_265224	ENST00000330953.5	chr3_32955451_+	-1191.30	-1188.20	-1222.30
CAediting_265225	ENST00000330953.5	chr3_32955487_+	-1187.30	-1188.20	-1222.30
CAediting_265226	ENST00000330953.5	chr3_32955489_+	-1187.60	-1188.20	-1222.30
CAediting_265227	ENST00000330953.5	chr3_32955497_+	-1184.80	-1188.20	-1222.30
CAediting_265228	ENST00000330953.5	chr3_32955547_+	-1188.30	-1188.20	-1222.30
CAediting_265229	ENST00000330953.5	chr3_32955636_+	-1194.00	-1188.20	-1222.30
CAediting_265230	ENST00000330953.5	chr3_32955660_+	-1187.30	-1188.20	-1222.30
CAediting_265231	ENST00000330953.5	chr3_32955674_+	-1187.60	-1188.20	-1222.30
CAediting_265232	ENST00000330953.5	chr3_32955690_+	-1187.90	-1188.20	-1222.30
CAediting_265233	ENST00000330953.5	chr3_32955714_+	-1188.50	-1188.20	-1222.30
CAediting_265234	ENST00000330953.5	chr3_32955727_+	-1187.50	-1188.20	-1222.30
CAediting_265235	ENST00000330953.5	chr3_32955735_+	-1191.60	-1188.20	-1222.30
CAediting_265236	ENST00000330953.5	chr3_32955736_+	-1189.40	-1188.20	-1222.30
CAediting_265237	ENST00000330953.5	chr3_32955739_+	-1189.00	-1188.20	-1222.30
CAediting_265238	ENST00000330953.5	chr3_32955749_+	-1188.80	-1188.20	-1222.30
CAediting_265239	ENST00000330953.5	chr3_32955751_+	-1190.40	-1188.20	-1222.30
CAediting_265240	ENST00000330953.5	chr3_32955755_+	-1187.50	-1188.20	-1222.30
CAediting_265241	ENST00000330953.5	chr3_32955791_+	-1188.20	-1188.20	-1222.30
CAediting_265242	ENST00000330953.5	chr3_32955794_+	-1188.40	-1188.20	-1222.30
CAediting_265243	ENST00000330953.5	chr3_32955796_+	-1189.80	-1188.20	-1222.30
CAediting_265244	ENST00000330953.5	chr3_32955808_+	-1187.80	-1188.20	-1222.30
CAediting_265245	ENST00000330953.5	chr3_32955816_+	-1187.50	-1188.20	-1222.30
CAediting_265246	ENST00000330953.5	chr3_32955819_+	-1189.60	-1188.20	-1222.30
CAediting_265247	ENST00000330953.5	chr3_32955820_+	-1189.90	-1188.20	-1222.30
CAediting_265248	ENST00000330953.5	chr3_32955870_+	-1190.90	-1188.20	-1222.30
CAediting_265249	ENST00000330953.5	chr3_32955883_+	-1188.20	-1188.20	-1222.30
CAediting_265250	ENST00000330953.5	chr3_32955929_+	-1188.20	-1188.20	-1222.30
CAediting_265251	ENST00000330953.5	chr3_32955952_+	-1188.20	-1188.20	-1222.30
CAediting_265252	ENST00000330953.5	chr3_32955971_+	-1190.70	-1188.20	-1222.30
CAediting_265253	ENST00000330953.5	chr3_32956016_+	-1191.70	-1188.20	-1222.30
CAediting_265254	ENST00000330953.5	chr3_32956023_+	-1190.30	-1188.20	-1222.30
CAediting_265255	ENST00000330953.5	chr3_32956040_+	-1187.50	-1188.20	-1222.30
CAediting_265256	ENST00000330953.5	chr3_32956048_+	-1189.40	-1188.20	-1222.30
CAediting_265257	ENST00000330953.5	chr3_32956049_+	-1190.60	-1188.20	-1222.30
CAediting_265258	ENST00000330953.5	chr3_32956052_+	-1189.40	-1188.20	-1222.30
CAediting_265259	ENST00000330953.5	chr3_32956062_+	-1189.10	-1188.20	-1222.30
CAediting_265260	ENST00000330953.5	chr3_32956064_+	-1189.00	-1188.20	-1222.30
CAediting_265261	ENST00000330953.5	chr3_32956088_+	-1188.70	-1188.20	-1222.30
CAediting_265262	ENST00000330953.5	chr3_32956089_+	-1188.20	-1188.20	-1222.30
CAediting_265263	ENST00000330953.5	chr3_32956103_+	-1187.90	-1188.20	-1222.30
CAediting_265264	ENST00000330953.5	chr3_32956106_+	-1187.90	-1188.20	-1222.30
CAediting_265265	ENST00000330953.5	chr3_32956120_+	-1189.20	-1188.20	-1222.30
CAediting_265266	ENST00000330953.5	chr3_32956125_+	-1194.40	-1188.20	-1222.30
CAediting_265267	ENST00000330953.5	chr3_32956132_+	-1187.50	-1188.20	-1222.30
CAediting_265268	ENST00000330953.5	chr3_32956197_+	-1188.20	-1188.20	-1222.30

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Relation with ADAR for CCR4

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for CCR4

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BRCA	pathologic_stage	CAediting_265238	chr3_32955749_+	0.048808232604403	0.158536304495531
BRCA	pathologic_stage	CAediting_265245	chr3_32955816_+	0.00372723000570558	0.246224599648466
STAD	pathologic_stage	CAediting_265238	chr3_32955749_+	0.0384439744277905	0.242837398737557

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Relation with survival for CCR4

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
BRCA	CAediting_265238	chr3_32955749_+	0.00127099080781512	0.000299639	1017.37

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RelatedDrugs for CCR4

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
CCR4	P51679	DB12498	Mogamulizumab	C-C chemokine receptor type 4	BiotechDrug	approved\|investigational

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RelatedDiseases for CCR4

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
CCR4	C0007570	Celiac Disease	1	CTD_human
CCR4	C0007786	Brain Ischemia	1	CTD_human
CCR4	C0017638	Glioma	1	CTD_human
CCR4	C0023493	Adult T-Cell Lymphoma/Leukemia	1	CTD_human
CCR4	C0023903	Liver neoplasms	1	CTD_human
CCR4	C0036920	Sezary Syndrome	1	CTD_human
CCR4	C0259783	mixed gliomas	1	CTD_human
CCR4	C0345904	Malignant neoplasm of liver	1	CTD_human
CCR4	C0555198	Malignant Glioma	1	CTD_human
CCR4	C0917798	Cerebral Ischemia	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene