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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: GALNT15 (CAeditome ID:117248)

Gene summary for GALNT15

check button Gene summary
Gene informationGene symbol

GALNT15

Gene ID

117248

Gene namepolypeptide N-acetylgalactosaminyltransferase 15
SynonymsGALNACT15|GALNT13|GALNT7|GALNTL2|PIH5|pp-GalNAc-T15
Cytomap

3p25.1

Type of geneprotein-coding
Descriptionpolypeptide N-acetylgalactosaminyltransferase 15UDP-GalNAc transferase T15UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 2UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15UDP-N-acetyl-alpha-D-ga
Modification date20210518
UniProtAcc

Q8N3T1

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
GALNT15

GO:0030133

Polypeptide N-acetylgalactosaminyltransferase 15

0000054


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RNA A-to-I events for GALNT15

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000131386.16
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_261482(16202582, +), CAediting_261483(16202620, +), CAediting_261484(16206628, +), CAediting_261485(16209764, +), CAediting_261486(16213357, +), CAediting_261487(16215865, +), CAediting_261488(16215870, +), CAediting_261489(16225441, +), CAediting_261490(16225447, +), CAediting_261491(16225994, +), CAediting_261492(16228391, +), CAediting_261493(16228421, +), CAediting_261494(16228442, +), CAediting_261495(16228488, +), CAediting_261496(16228520, +), CAediting_261497(16228526, +), CAediting_261498(16228543, +), CAediting_261499(16228586, +), CAediting_261500(16228596, +), CAediting_261501(16228629, +), CAediting_261502(16230553, +), CAediting_261503(16230554, +), CAediting_261504(16230569, +), CAediting_261505(16230570, +), CAediting_261506(16230573, +), CAediting_261507(16230595, +), CAediting_261508(16230601, +), CAediting_261509(16230604, +), CAediting_261510(16230609, +), CAediting_261511(16230614, +), CAediting_261512(16230619, +), CAediting_261513(16230621, +), CAediting_261514(16230648, +), CAediting_261515(16230676, +), CAediting_261516(16230678, +), CAediting_261517(16230679, +), CAediting_261518(16230684, +), CAediting_261519(16230691, +), CAediting_261520(16230728, +), CAediting_261521(16230920, +), CAediting_261522(16230921, +), CAediting_261523(16230927, +), CAediting_261524(16230934, +),

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RNA editing positional annotations for GALNT15 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_261482chr3_16202582_+intronic
CAediting_261483chr3_16202620_+intronic
CAediting_261484chr3_16206628_+intronic
CAediting_261485chr3_16209764_+intronic
CAediting_261486chr3_16213357_+ncRNA_intronic
CAediting_261487chr3_16215865_+ncRNA_intronic
CAediting_261488chr3_16215870_+ncRNA_intronic
CAediting_261489chr3_16225441_+intronic
CAediting_261490chr3_16225447_+intronic
CAediting_261491chr3_16225994_+intronic
CAediting_261492chr3_16228391_+UTR3
CAediting_261493chr3_16228421_+UTR3
CAediting_261494chr3_16228442_+UTR3
CAediting_261495chr3_16228488_+UTR3
CAediting_261496chr3_16228520_+UTR3
CAediting_261497chr3_16228526_+UTR3
CAediting_261498chr3_16228543_+UTR3
CAediting_261499chr3_16228586_+UTR3
CAediting_261500chr3_16228596_+UTR3
CAediting_261501chr3_16228629_+UTR3
CAediting_261502chr3_16230553_+intronic
CAediting_261503chr3_16230554_+intronic
CAediting_261504chr3_16230569_+intronic
CAediting_261505chr3_16230570_+intronic
CAediting_261506chr3_16230573_+intronic
CAediting_261507chr3_16230595_+intronic
CAediting_261508chr3_16230601_+intronic
CAediting_261509chr3_16230604_+intronic
CAediting_261510chr3_16230609_+intronic
CAediting_261511chr3_16230614_+intronic
CAediting_261512chr3_16230619_+intronic
CAediting_261513chr3_16230621_+intronic
CAediting_261514chr3_16230648_+intronic
CAediting_261515chr3_16230676_+intronic
CAediting_261516chr3_16230678_+intronic
CAediting_261517chr3_16230679_+intronic
CAediting_261518chr3_16230684_+intronic
CAediting_261519chr3_16230691_+intronic
CAediting_261520chr3_16230728_+intronic
CAediting_261521chr3_16230920_+intronic
CAediting_261522chr3_16230921_+intronic
CAediting_261523chr3_16230927_+intronic
CAediting_261524chr3_16230934_+intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_261482chr3_16202582_+SINEAluAluSx
CAediting_261483chr3_16202620_+SINEAluAluSx
CAediting_261484chr3_16206628_+SINEAluAluY
CAediting_261485chr3_16209764_+SINEAluAluSz6
CAediting_261486chr3_16213357_+SINEAluAluY
CAediting_261487chr3_16215865_+SINEAluAluSc
CAediting_261488chr3_16215870_+SINEAluAluSc
CAediting_261489chr3_16225441_+SINEAluAluSx4
CAediting_261490chr3_16225447_+SINEAluAluSx4
CAediting_261491chr3_16225994_+SINEAluAluSz
CAediting_261492chr3_16228391_+SINEAluAluSx
CAediting_261493chr3_16228421_+SINEAluAluSx
CAediting_261494chr3_16228442_+SINEAluAluSx
CAediting_261495chr3_16228488_+SINEAluAluSx
CAediting_261496chr3_16228520_+SINEAluAluSx
CAediting_261497chr3_16228526_+SINEAluAluSx
CAediting_261498chr3_16228543_+SINEAluAluSx
CAediting_261499chr3_16228586_+SINEAluAluSx
CAediting_261500chr3_16228596_+SINEAluAluSx
CAediting_261501chr3_16228629_+SINEAluAluSx
CAediting_261507chr3_16230595_+Simple_repeatSimple_repeat(A)n
CAediting_261508chr3_16230601_+Simple_repeatSimple_repeat(A)n
CAediting_261509chr3_16230604_+Simple_repeatSimple_repeat(A)n
CAediting_261521chr3_16230920_+LINEL1L1PA8
CAediting_261522chr3_16230921_+LINEL1L1PA8
CAediting_261523chr3_16230927_+LINEL1L1PA8
CAediting_261524chr3_16230934_+LINEL1L1PA8

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RNA A-to-I editing events in the alternative splicing sites for GALNT15

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000131386.16.GALNT15.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000131386.16.GALNT15.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for GALNT15

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
LGG.CAediting_261509.ENSG00000131386.GALNT15.png
Soverview
LGG.CAediting_261511.ENSG00000131386.GALNT15.png
Soverview
LGG.CAediting_261517.ENSG00000131386.GALNT15.png
Soverview
LGG.CAediting_261518.ENSG00000131386.GALNT15.png
Soverview

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Protein coding region RNA A-to-I editings for GALNT15

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for GALNT15

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_261492chr3_16228391_+ENSG00000131386.16ENST00000617544hsa-miR-371a-3p16228389162283957mer-m81622837416228396144.00-15.05
CAediting_261493chr3_16228421_+ENSG00000131386.16ENST00000617544hsa-miR-805316228417162284226mer1622839916228423140.00-19.98
CAediting_261494chr3_16228442_+ENSG00000131386.16ENST00000617544hsa-miR-317616228439162284457mer-m81622842816228446152.00-22.34
CAediting_261494chr3_16228442_+ENSG00000131386.16ENST00000617544hsa-miR-3922-3p16228439162284457mer-m81622842116228446157.00-22.43
CAediting_261494chr3_16228442_+ENSG00000131386.16ENST00000617544hsa-miR-6878-3p16228438162284447mer-m81622842516228445144.00-23.86
CAediting_261496chr3_16228520_+ENSG00000131386.16ENST00000617544hsa-miR-513a-5p16228514162285207mer-m81622850416228521156.00-21.69
CAediting_261496chr3_16228520_+ENSG00000131386.16ENST00000617544hsa-miR-513a-5p16228514162285207mer-m81622850416228521156.00-21.69
CAediting_261496chr3_16228520_+ENSG00000131386.16ENST00000617544hsa-miR-63816228519162285257mer-1a1622850116228525151.00-30.81
CAediting_261499chr3_16228586_+ENSG00000131386.16ENST00000617544hsa-miR-324-3p16228579162285857mer-m81622856416228586149.00-24.91
CAediting_261499chr3_16228586_+ENSG00000131386.16ENST00000617544hsa-miR-4690-3p16228583162285908mer-1a1622857116228590165.00-31.39
CAediting_261499chr3_16228586_+ENSG00000131386.16ENST00000617544hsa-miR-568516228583162285908mer-1a1622857016228590149.00-19.15
CAediting_261500chr3_16228596_+ENSG00000131386.16ENST00000617544hsa-miR-56416228594162286007mer-1a1622858216228600151.00-24.87
CAediting_261501chr3_16228629_+ENSG00000131386.16ENST00000617544hsa-miR-3156-3p16228624162286307mer-m81622861116228631141.00-17.24
CAediting_261501chr3_16228629_+ENSG00000131386.16ENST00000617544hsa-miR-3156-3p16228624162286307mer-m81622861116228631141.00-17.24
CAediting_261501chr3_16228629_+ENSG00000131386.16ENST00000617544hsa-miR-4433a-5p16228625162286317mer-m81622861116228632148.00-20.47
CAediting_261501chr3_16228629_+ENSG00000131386.16ENST00000617544hsa-miR-5588-3p16228626162286327mer-m81622861616228633155.00-18.42
CAediting_261501chr3_16228629_+ENSG00000131386.16ENST00000617544hsa-miR-6777-3p16228622162286287mer-m81622861116228629146.00-22.29
CAediting_261495chr3_16228488_+ENSG00000131386.16ENST00000617544hsa-miR-4742-3p16228481162284888mer-1a1622846616228488142.00-9.18
CAediting_261498chr3_16228543_+ENSG00000131386.16ENST00000617544hsa-miR-6849-3p16228536162285427mer-m81622852216228543140.00-18.03

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_261496chr3_16228520_+ENSG00000131386.16ENST00000617544hsa-miR-10399-5p16228515162285217mer-m81622850116228522152-11.23
CAediting_261493chr3_16228421_+ENSG00000131386.16ENST00000617544hsa-miR-125a-3p16228418162284258mer-1a1622840416228425149-18.88
CAediting_261498chr3_16228543_+ENSG00000131386.16ENST00000617544hsa-miR-3152-5p16228541162285477mer-m81622852516228548151-19.12
CAediting_261494chr3_16228442_+ENSG00000131386.16ENST00000617544hsa-miR-3663-5p16228439162284457mer-m81622842616228446140-19.33
CAediting_261497chr3_16228526_+ENSG00000131386.16ENST00000617544hsa-miR-5089-5p16228519162285257mer-m81622850616228526151-15.19
CAediting_261492chr3_16228391_+ENSG00000131386.16ENST00000617544hsa-miR-512-3p16228389162283957mer-m81622837516228396149-15
CAediting_261492chr3_16228391_+ENSG00000131386.16ENST00000617544hsa-miR-512-3p16228389162283957mer-m81622837516228396149-15
CAediting_261494chr3_16228442_+ENSG00000131386.16ENST00000617544hsa-miR-613116228440162284467mer-m81622842916228447140-16.72
CAediting_261496chr3_16228520_+ENSG00000131386.16ENST00000617544hsa-miR-6504-3p16228515162285217mer-m81622850316228522140-13.14
CAediting_261497chr3_16228526_+ENSG00000131386.16ENST00000617544hsa-miR-6506-5p16228520162285267mer-m81622850616228527147-15.75
CAediting_261501chr3_16228629_+ENSG00000131386.16ENST00000617544hsa-miR-6794-3p16228622162286287mer-m81622861216228629150-20.62
CAediting_261494chr3_16228442_+ENSG00000131386.16ENST00000617544hsa-miR-6843-3p16228438162284447mer-m81622842616228445148-20.39
CAediting_261494chr3_16228442_+ENSG00000131386.16ENST00000617544hsa-miR-6848-3p16228438162284447mer-m81622842816228445150-22.55
CAediting_261501chr3_16228629_+ENSG00000131386.16ENST00000617544hsa-miR-92416228628162286336mer1622861516228634140-15.61

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_688080chr9_63819626_+ENSG00000131386.16ENST00000437509hsa-miR-4477b16231897162319037mer-m81623188516231904157-14.89
CAediting_980496chr14_31014685_-ENSG00000131386.16ENST00000617544hsa-miR-624-3p16228674162286796mer1622866016228680143-17.34
CAediting_393chr1_1167164_+ENSG00000131386.16ENST00000617544hsa-miR-200b-3p16229022162290287mer-m81622900816229029152-9.1
CAediting_688080chr9_63819626_+ENSG00000131386.16ENST00000617544hsa-miR-4477b16229353162293597mer-m81622934116229360151-12.73
CAediting_688081chr9_63819627_+ENSG00000131386.16ENST00000617544hsa-miR-4477b16229555162295628mer-1a1622954116229562167-15.68
CAediting_396018chr5_1062918_-ENSG00000131386.16ENST00000437509hsa-miR-463516231898162319058mer-1a1623188216231905145-15.27
CAediting_1368054chr19_46709310_-ENSG00000131386.16ENST00000617544hsa-miR-320e16228092162280998mer-1a1622808216228099141-16.69
CAediting_1399425chr20_1392958_-ENSG00000131386.16ENST00000617544hsa-miR-6869-5p16229387162293937mer-m81622937416229394153-24.47
CAediting_228905chr2_188297554_+ENSG00000131386.16ENST00000617544hsa-miR-561-3p16228660162286667mer-m81622864616228667140-10.04
CAediting_228905chr2_188297554_+ENSG00000131386.16ENST00000617544hsa-miR-561-3p16227959162279657mer-m81622794516227966140-11.29
CAediting_228905chr2_188297554_+ENSG00000131386.16ENST00000617544hsa-miR-561-3p16228349162283557mer-m81622833516228356152-9.77
CAediting_468389chr6_31355314_-ENSG00000131386.16ENST00000437509hsa-miR-6891-5p16231923162319286mer1623191116231929141-20.15

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_442554chr5_154685830_+ENSG00000131386.16ENST00000617544hsa-miR-130316228225162282317mer-m81622821116228232151-11.85
CAediting_1351755chr19_40282625_-ENSG00000131386.16ENST00000617544hsa-miR-64116229515162295206mer1622949816229521141-15.9

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for GALNT15

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000339732.8protein_codingSoverviewSoverview
ENST00000617544.3protein_codingSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_261492ENST00000339732.8chr3_16228391_+-1591.90-1589.00-1595.80
CAediting_261493ENST00000339732.8chr3_16228421_+-1588.80-1589.00-1595.80
CAediting_261494ENST00000339732.8chr3_16228442_+-1589.30-1589.00-1595.80
CAediting_261495ENST00000339732.8chr3_16228488_+-1589.00-1589.00-1595.80
CAediting_261496ENST00000339732.8chr3_16228520_+-1590.50-1589.00-1595.80
CAediting_261497ENST00000339732.8chr3_16228526_+-1588.30-1589.00-1595.80
CAediting_261498ENST00000339732.8chr3_16228543_+-1590.90-1589.00-1595.80
CAediting_261499ENST00000339732.8chr3_16228586_+-1590.80-1589.00-1595.80
CAediting_261500ENST00000339732.8chr3_16228596_+-1588.40-1589.00-1595.80
CAediting_261501ENST00000339732.8chr3_16228629_+-1587.40-1589.00-1595.80
CAediting_261492ENST00000617544.3chr3_16228391_+-835.87-832.97-843.40
CAediting_261493ENST00000617544.3chr3_16228421_+-832.77-832.97-843.40
CAediting_261494ENST00000617544.3chr3_16228442_+-833.27-832.97-843.40
CAediting_261495ENST00000617544.3chr3_16228488_+-832.97-832.97-843.40
CAediting_261496ENST00000617544.3chr3_16228520_+-834.47-832.97-843.40
CAediting_261497ENST00000617544.3chr3_16228526_+-832.27-832.97-843.40
CAediting_261498ENST00000617544.3chr3_16228543_+-834.87-832.97-843.40
CAediting_261499ENST00000617544.3chr3_16228586_+-834.77-832.97-843.40
CAediting_261500ENST00000617544.3chr3_16228596_+-834.10-832.97-843.40
CAediting_261501ENST00000617544.3chr3_16228629_+-831.37-832.97-843.40

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Relation with ADAR for GALNT15

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
LGGCAediting_261502chr3_16230553_+1.85579373044865e-140.49020215617396....
LGGCAediting_261509chr3_16230604_+1.21114544095637e-110.300514685618185....
GBMCAediting_261509chr3_16230604_+8.62799656660171e-070.390293678089132....
SARCCAediting_261509chr3_16230604_+7.74699679083408e-060.422877262009553....
LGGCAediting_261510chr3_16230609_+1.85363795119699e-130.45934618018465....
GBMCAediting_261510chr3_16230609_+1.16584776280253e-060.509825915767061....
LGGCAediting_261511chr3_16230614_+2.12202917117028e-190.401888482203679....
BRCACAediting_261511chr3_16230614_+0.0162407042300030.20808411386144....
GBMCAediting_261511chr3_16230614_+9.26390680093406e-110.503557736200652....
KIRCCAediting_261511chr3_16230614_+0.003453006255985170.182835692562682....
SARCCAediting_261511chr3_16230614_+0.0001024435894838020.411117055723769....
LGGCAediting_261516chr3_16230678_+2.98203286744238e-070.461756093580888....
LGGCAediting_261517chr3_16230679_+1.04967491297135e-260.468611151562823....
GBMCAediting_261517chr3_16230679_+2.07266690601963e-080.467365239443762....
SARCCAediting_261517chr3_16230679_+0.0003994354039167190.361495325154497....
LGGCAediting_261518chr3_16230684_+3.85420942007507e-250.499664137405435....
GBMCAediting_261518chr3_16230684_+2.58095722001215e-050.375464056733531....
SARCCAediting_261518chr3_16230684_+9.00647073392835e-050.469728495227677....

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Relation with cancer stages for GALNT15

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
BRCApathologic_stageCAediting_261509chr3_16230604_+0.01568331963149430.223907539115188
BRCApathologic_stageCAediting_261517chr3_16230679_+0.01024440472670850.236524024116673
BRCApathologic_stageCAediting_261518chr3_16230684_+0.00390286796787090.331578505698489
KIRCpathologic_stageCAediting_261510chr3_16230609_+0.03518320237928480.235863923492914
KIRCpathologic_stageCAediting_261518chr3_16230684_+0.04826397363537920.158915533806992

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Relation with survival for GALNT15

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for GALNT15

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for GALNT15

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource