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Editing gene: ALPK2 (CAeditome ID:115701)

Gene summary for ALPK2

Gene summary

Gene information	Gene symbol	ALPK2
	Gene ID	115701
	Gene name	alpha kinase 2
	Synonyms	HAK
	Cytomap	18q21.31-q21.32
	Type of gene	protein-coding
	Description	alpha-protein kinase 2heart alpha-kinaseheart alpha-protein kinase
	Modification date	20210518
	UniProtAcc	Q86TB3
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for ALPK2

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000198796.6

RNA A-to-I editing events in Cancer.

CAediting_1266386(58483589, -), CAediting_1266387(58483616, -), CAediting_1266388(58483623, -), CAediting_1266389(58483626, -), CAediting_1266390(58483639, -), CAediting_1266391(58483647, -), CAediting_1266392(58483666, -), CAediting_1266393(58483683, -), CAediting_1266394(58483689, -), CAediting_1266395(58483725, -), CAediting_1266396(58483727, -), CAediting_1266397(58483837, -), CAediting_1266398(58483838, -), CAediting_1266399(58483846, -), CAediting_1266400(58484578, -), CAediting_1266401(58484600, -), CAediting_1266402(58484622, -), CAediting_1266403(58484644, -), CAediting_1266404(58484657, -), CAediting_1266405(58484660, -), CAediting_1266406(58484681, -), CAediting_1266407(58484706, -), CAediting_1266408(58484716, -), CAediting_1266409(58487777, -), CAediting_1266410(58489468, -), CAediting_1266411(58489489, -), CAediting_1266412(58489574, -), CAediting_1266413(58489601, -), CAediting_1266414(58489605, -), CAediting_1266415(58489653, -), CAediting_1266416(58489681, -), CAediting_1266417(58489868, -), CAediting_1266418(58489959, -), CAediting_1266419(58489964, -), CAediting_1266420(58520171, -), CAediting_1266421(58520236, -), CAediting_1266422(58520384, -), CAediting_1266423(58520385, -), CAediting_1266424(58520390, -), CAediting_1266425(58520398, -), CAediting_1266426(58521659, -), CAediting_1266427(58521690, -), CAediting_1266428(58521700, -), CAediting_1266429(58521752, -), CAediting_1266430(58521756, -), CAediting_1266431(58521760, -), CAediting_1266432(58521765, -), CAediting_1266433(58521766, -), CAediting_1266434(58521792, -), CAediting_1266435(58521854, -), CAediting_1266436(58521908, -), CAediting_1266437(58528474, -), CAediting_1266438(58538735, -), CAediting_1266439(58538736, -), CAediting_1266440(58538742, -), CAediting_1266441(58538748, -), CAediting_1266442(58538755, -), CAediting_1266443(58538762, -), CAediting_1266444(58538765, -), CAediting_1266445(58538772, -), CAediting_1266446(58538774, -), CAediting_1266447(58538775, -), CAediting_1266448(58538776, -), CAediting_1266449(58538780, -), CAediting_1266450(58538781, -), CAediting_1266451(58538783, -), CAediting_1266452(58538789, -), CAediting_1266453(58538793, -), CAediting_1266454(58538797, -), CAediting_1266455(58538798, -), CAediting_1266456(58538809, -), CAediting_1266457(58538810, -), CAediting_1266458(58538812, -), CAediting_1266459(58538841, -), CAediting_1266460(58538867, -), CAediting_1266461(58538882, -), CAediting_1266462(58538979, -), CAediting_1266463(58538995, -), CAediting_1266464(58539044, -), CAediting_1266465(58539055, -), CAediting_1266466(58539057, -), CAediting_1266467(58539061, -), CAediting_1266468(58539090, -), CAediting_1266469(58541130, -), CAediting_1266470(58541131, -), CAediting_1266471(58541133, -), CAediting_1266472(58541198, -), CAediting_1266473(58541211, -), CAediting_1266474(58541221, -), CAediting_1266475(58541228, -), CAediting_1266476(58541257, -), CAediting_1266477(58541298, -), CAediting_1266478(58541308, -), CAediting_1266479(58541310, -), CAediting_1266480(58541311, -), CAediting_1266481(58541373, -), CAediting_1266482(58541380, -), CAediting_1266483(58541381, -), CAediting_1266484(58541384, -), CAediting_1266485(58541400, -), CAediting_1266486(58541403, -), CAediting_1266487(58541408, -), CAediting_1266488(58541413, -), CAediting_1266489(58541419, -), CAediting_1266490(58541438, -), CAediting_1266491(58541444, -), CAediting_1266492(58541445, -), CAediting_1266493(58541451, -),

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RNA editing positional annotations for ALPK2 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1266386	chr18_58483589_-	intronic
CAediting_1266387	chr18_58483616_-	intronic
CAediting_1266388	chr18_58483623_-	intronic
CAediting_1266389	chr18_58483626_-	intronic
CAediting_1266390	chr18_58483639_-	intronic
CAediting_1266391	chr18_58483647_-	intronic
CAediting_1266392	chr18_58483666_-	intronic
CAediting_1266393	chr18_58483683_-	intronic
CAediting_1266394	chr18_58483689_-	intronic
CAediting_1266395	chr18_58483725_-	intronic
CAediting_1266396	chr18_58483727_-	intronic
CAediting_1266397	chr18_58483837_-	intronic
CAediting_1266398	chr18_58483838_-	intronic
CAediting_1266399	chr18_58483846_-	intronic
CAediting_1266400	chr18_58484578_-	intronic
CAediting_1266401	chr18_58484600_-	intronic
CAediting_1266402	chr18_58484622_-	intronic
CAediting_1266403	chr18_58484644_-	intronic
CAediting_1266404	chr18_58484657_-	intronic
CAediting_1266405	chr18_58484660_-	intronic
CAediting_1266406	chr18_58484681_-	intronic
CAediting_1266407	chr18_58484706_-	intronic
CAediting_1266408	chr18_58484716_-	intronic
CAediting_1266409	chr18_58487777_-	intronic
CAediting_1266410	chr18_58489468_-	intronic
CAediting_1266411	chr18_58489489_-	intronic
CAediting_1266412	chr18_58489574_-	intronic
CAediting_1266413	chr18_58489601_-	intronic
CAediting_1266414	chr18_58489605_-	intronic
CAediting_1266415	chr18_58489653_-	intronic
CAediting_1266416	chr18_58489681_-	intronic
CAediting_1266417	chr18_58489868_-	intronic
CAediting_1266418	chr18_58489959_-	intronic
CAediting_1266419	chr18_58489964_-	intronic
CAediting_1266420	chr18_58520171_-	intronic
CAediting_1266421	chr18_58520236_-	intronic
CAediting_1266422	chr18_58520384_-	intronic
CAediting_1266423	chr18_58520385_-	intronic
CAediting_1266424	chr18_58520390_-	intronic
CAediting_1266425	chr18_58520398_-	intronic
CAediting_1266426	chr18_58521659_-	intronic
CAediting_1266427	chr18_58521690_-	intronic
CAediting_1266428	chr18_58521700_-	intronic
CAediting_1266429	chr18_58521752_-	intronic
CAediting_1266430	chr18_58521756_-	intronic
CAediting_1266431	chr18_58521760_-	intronic
CAediting_1266432	chr18_58521765_-	intronic
CAediting_1266433	chr18_58521766_-	intronic
CAediting_1266434	chr18_58521792_-	intronic
CAediting_1266435	chr18_58521854_-	intronic
CAediting_1266436	chr18_58521908_-	intronic
CAediting_1266437	chr18_58528474_-	intronic
CAediting_1266438	chr18_58538735_-	ncRNA_intronic
CAediting_1266439	chr18_58538736_-	ncRNA_intronic
CAediting_1266440	chr18_58538742_-	ncRNA_intronic
CAediting_1266441	chr18_58538748_-	ncRNA_intronic
CAediting_1266442	chr18_58538755_-	ncRNA_intronic
CAediting_1266443	chr18_58538762_-	ncRNA_intronic
CAediting_1266444	chr18_58538765_-	ncRNA_intronic
CAediting_1266445	chr18_58538772_-	ncRNA_intronic
CAediting_1266446	chr18_58538774_-	ncRNA_intronic
CAediting_1266447	chr18_58538775_-	ncRNA_intronic
CAediting_1266448	chr18_58538776_-	ncRNA_intronic
CAediting_1266449	chr18_58538780_-	ncRNA_intronic
CAediting_1266450	chr18_58538781_-	ncRNA_intronic
CAediting_1266451	chr18_58538783_-	ncRNA_intronic
CAediting_1266452	chr18_58538789_-	ncRNA_intronic
CAediting_1266453	chr18_58538793_-	ncRNA_intronic
CAediting_1266454	chr18_58538797_-	ncRNA_intronic
CAediting_1266455	chr18_58538798_-	ncRNA_intronic
CAediting_1266456	chr18_58538809_-	ncRNA_intronic
CAediting_1266457	chr18_58538810_-	ncRNA_intronic
CAediting_1266458	chr18_58538812_-	ncRNA_intronic
CAediting_1266459	chr18_58538841_-	ncRNA_intronic
CAediting_1266460	chr18_58538867_-	ncRNA_intronic
CAediting_1266461	chr18_58538882_-	ncRNA_intronic
CAediting_1266462	chr18_58538979_-	ncRNA_intronic
CAediting_1266463	chr18_58538995_-	ncRNA_intronic
CAediting_1266464	chr18_58539044_-	ncRNA_intronic
CAediting_1266465	chr18_58539055_-	ncRNA_intronic
CAediting_1266466	chr18_58539057_-	ncRNA_intronic
CAediting_1266467	chr18_58539061_-	ncRNA_intronic
CAediting_1266468	chr18_58539090_-	ncRNA_intronic
CAediting_1266469	chr18_58541130_-	ncRNA_intronic
CAediting_1266470	chr18_58541131_-	ncRNA_intronic
CAediting_1266471	chr18_58541133_-	ncRNA_intronic
CAediting_1266472	chr18_58541198_-	ncRNA_intronic
CAediting_1266473	chr18_58541211_-	ncRNA_intronic
CAediting_1266474	chr18_58541221_-	ncRNA_intronic
CAediting_1266475	chr18_58541228_-	ncRNA_intronic
CAediting_1266476	chr18_58541257_-	ncRNA_intronic
CAediting_1266477	chr18_58541298_-	ncRNA_intronic
CAediting_1266478	chr18_58541308_-	ncRNA_intronic
CAediting_1266479	chr18_58541310_-	ncRNA_intronic
CAediting_1266480	chr18_58541311_-	ncRNA_intronic
CAediting_1266481	chr18_58541373_-	ncRNA_intronic
CAediting_1266482	chr18_58541380_-	ncRNA_intronic
CAediting_1266483	chr18_58541381_-	ncRNA_intronic
CAediting_1266484	chr18_58541384_-	ncRNA_intronic
CAediting_1266485	chr18_58541400_-	ncRNA_intronic
CAediting_1266486	chr18_58541403_-	ncRNA_intronic
CAediting_1266487	chr18_58541408_-	ncRNA_intronic
CAediting_1266488	chr18_58541413_-	ncRNA_intronic
CAediting_1266489	chr18_58541419_-	ncRNA_intronic
CAediting_1266490	chr18_58541438_-	ncRNA_intronic
CAediting_1266491	chr18_58541444_-	ncRNA_intronic
CAediting_1266492	chr18_58541445_-	ncRNA_intronic
CAediting_1266493	chr18_58541451_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1266386	chr18_58483589_-	SINE	Alu	AluSq2
CAediting_1266387	chr18_58483616_-	SINE	Alu	AluSq2
CAediting_1266388	chr18_58483623_-	SINE	Alu	AluSq2
CAediting_1266389	chr18_58483626_-	SINE	Alu	AluSq2
CAediting_1266390	chr18_58483639_-	SINE	Alu	AluSq2
CAediting_1266391	chr18_58483647_-	SINE	Alu	AluSq2
CAediting_1266392	chr18_58483666_-	SINE	Alu	AluSq2
CAediting_1266393	chr18_58483683_-	SINE	Alu	AluSq2
CAediting_1266394	chr18_58483689_-	SINE	Alu	AluSq2
CAediting_1266395	chr18_58483725_-	SINE	Alu	AluSq2
CAediting_1266396	chr18_58483727_-	SINE	Alu	AluSq2
CAediting_1266397	chr18_58483837_-	SINE	Alu	AluSq2
CAediting_1266398	chr18_58483838_-	SINE	Alu	AluSq2
CAediting_1266399	chr18_58483846_-	SINE	Alu	AluSq2
CAediting_1266400	chr18_58484578_-	SINE	Alu	AluSc
CAediting_1266401	chr18_58484600_-	SINE	Alu	AluSc
CAediting_1266402	chr18_58484622_-	SINE	Alu	AluSc
CAediting_1266403	chr18_58484644_-	SINE	Alu	AluSc
CAediting_1266404	chr18_58484657_-	SINE	Alu	AluSc
CAediting_1266405	chr18_58484660_-	SINE	Alu	AluSc
CAediting_1266406	chr18_58484681_-	SINE	Alu	AluSc
CAediting_1266407	chr18_58484706_-	SINE	Alu	AluSc
CAediting_1266408	chr18_58484716_-	SINE	Alu	AluSc
CAediting_1266409	chr18_58487777_-	SINE	Alu	AluJo
CAediting_1266410	chr18_58489468_-	SINE	Alu	AluJo
CAediting_1266411	chr18_58489489_-	SINE	Alu	AluJo
CAediting_1266412	chr18_58489574_-	SINE	Alu	AluJo
CAediting_1266413	chr18_58489601_-	SINE	Alu	AluJo
CAediting_1266414	chr18_58489605_-	SINE	Alu	AluJo
CAediting_1266415	chr18_58489653_-	SINE	Alu	AluJo
CAediting_1266416	chr18_58489681_-	SINE	Alu	AluJo
CAediting_1266417	chr18_58489868_-	SINE	Alu	AluSc5
CAediting_1266418	chr18_58489959_-	SINE	Alu	AluSc5
CAediting_1266419	chr18_58489964_-	SINE	Alu	AluSc5
CAediting_1266420	chr18_58520171_-	SINE	Alu	AluSx1
CAediting_1266421	chr18_58520236_-	SINE	Alu	AluSx1
CAediting_1266422	chr18_58520384_-	SINE	Alu	AluSx1
CAediting_1266423	chr18_58520385_-	SINE	Alu	AluSx1
CAediting_1266424	chr18_58520390_-	SINE	Alu	AluSx1
CAediting_1266425	chr18_58520398_-	SINE	Alu	AluSx1
CAediting_1266426	chr18_58521659_-	SINE	Alu	AluSc
CAediting_1266427	chr18_58521690_-	SINE	Alu	AluSc
CAediting_1266428	chr18_58521700_-	SINE	Alu	AluSc
CAediting_1266429	chr18_58521752_-	SINE	Alu	AluSc
CAediting_1266430	chr18_58521756_-	SINE	Alu	AluSc
CAediting_1266431	chr18_58521760_-	SINE	Alu	AluSc
CAediting_1266432	chr18_58521765_-	SINE	Alu	AluSc
CAediting_1266433	chr18_58521766_-	SINE	Alu	AluSc
CAediting_1266434	chr18_58521792_-	SINE	Alu	AluSc
CAediting_1266435	chr18_58521854_-	SINE	Alu	AluSc
CAediting_1266436	chr18_58521908_-	SINE	Alu	AluSc
CAediting_1266437	chr18_58528474_-	SINE	Alu	AluJb
CAediting_1266438	chr18_58538735_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266439	chr18_58538736_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266440	chr18_58538742_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266441	chr18_58538748_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266442	chr18_58538755_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266443	chr18_58538762_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266444	chr18_58538765_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266445	chr18_58538772_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266446	chr18_58538774_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266447	chr18_58538775_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266448	chr18_58538776_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266449	chr18_58538780_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266450	chr18_58538781_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266451	chr18_58538783_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266452	chr18_58538789_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266453	chr18_58538793_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266454	chr18_58538797_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266455	chr18_58538798_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266456	chr18_58538809_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266457	chr18_58538810_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266458	chr18_58538812_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266459	chr18_58538841_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266460	chr18_58538867_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266461	chr18_58538882_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266462	chr18_58538979_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266463	chr18_58538995_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266464	chr18_58539044_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266465	chr18_58539055_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266466	chr18_58539057_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266467	chr18_58539061_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266468	chr18_58539090_-	LTR	ERVL-MaLR	MSTB1
CAediting_1266469	chr18_58541130_-	LTR	ERVL-MaLR	MSTA
CAediting_1266470	chr18_58541131_-	LTR	ERVL-MaLR	MSTA
CAediting_1266471	chr18_58541133_-	LTR	ERVL-MaLR	MSTA
CAediting_1266472	chr18_58541198_-	LTR	ERVL-MaLR	MSTA
CAediting_1266473	chr18_58541211_-	LTR	ERVL-MaLR	MSTA
CAediting_1266474	chr18_58541221_-	LTR	ERVL-MaLR	MSTA
CAediting_1266475	chr18_58541228_-	LTR	ERVL-MaLR	MSTA
CAediting_1266476	chr18_58541257_-	LTR	ERVL-MaLR	MSTA
CAediting_1266477	chr18_58541298_-	LTR	ERVL-MaLR	MSTA
CAediting_1266478	chr18_58541308_-	LTR	ERVL-MaLR	MSTA
CAediting_1266479	chr18_58541310_-	LTR	ERVL-MaLR	MSTA
CAediting_1266480	chr18_58541311_-	LTR	ERVL-MaLR	MSTA
CAediting_1266481	chr18_58541373_-	LTR	ERVL-MaLR	MSTA
CAediting_1266482	chr18_58541380_-	LTR	ERVL-MaLR	MSTA
CAediting_1266483	chr18_58541381_-	LTR	ERVL-MaLR	MSTA
CAediting_1266484	chr18_58541384_-	LTR	ERVL-MaLR	MSTA
CAediting_1266485	chr18_58541400_-	LTR	ERVL-MaLR	MSTA
CAediting_1266486	chr18_58541403_-	LTR	ERVL-MaLR	MSTA
CAediting_1266487	chr18_58541408_-	LTR	ERVL-MaLR	MSTA
CAediting_1266488	chr18_58541413_-	LTR	ERVL-MaLR	MSTA
CAediting_1266489	chr18_58541419_-	LTR	ERVL-MaLR	MSTA
CAediting_1266490	chr18_58541438_-	LTR	ERVL-MaLR	MSTA
CAediting_1266491	chr18_58541444_-	LTR	ERVL-MaLR	MSTA
CAediting_1266492	chr18_58541445_-	LTR	ERVL-MaLR	MSTA
CAediting_1266493	chr18_58541451_-	LTR	ERVL-MaLR	MSTA

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RNA A-to-I editing events in the alternative splicing sites for ALPK2

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000198796.6.ALPK2.

Correlation between RNA A-to-I editing and PSI for ENSG00000198796.6.ALPK2.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ALPK2

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for ALPK2

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for ALPK2

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ALPK2

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for ALPK2

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
KIRC	CAediting_1266447	chr18_58538775_-	.	.	0.0115959650745346	0.19042745983402	.	.
KIRC	CAediting_1266448	chr18_58538776_-	.	.	0.0195472024789497	0.223386908846789	.	.
KIRC	CAediting_1266449	chr18_58538780_-	0.0256538062760001	0.172669734971568	.	.	.	.
KIRC	CAediting_1266458	chr18_58538812_-	0.0136167602504865	0.199745715750453	.	.	.	.
KIRC	CAediting_1266481	chr18_58541373_-	0.021343676207713	0.280815912217443	.	.	.	.
KIRC	CAediting_1266482	chr18_58541380_-	.	.	0.00339019815501384	0.296176246329294	.	.

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Relation with cancer stages for ALPK2

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
KIRC	pathologic_stage	CAediting_1266439	chr18_58538736_-	0.0115578090193105	-0.272738391783576
KIRC	pathologic_stage	CAediting_1266447	chr18_58538775_-	0.0363271415851035	-0.158824699929529

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Relation with survival for ALPK2

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
KIRC	CAediting_1266462	chr18_58538979_-	0.00929583102444043	0.0173613	309.392

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RelatedDrugs for ALPK2

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for ALPK2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene