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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: GBP4 (CAeditome ID:115361)

Gene summary for GBP4

check button Gene summary
Gene informationGene symbol

GBP4

Gene ID

115361

Gene nameguanylate binding protein 4
SynonymsMpa2
Cytomap

1p22.2

Type of geneprotein-coding
Descriptionguanylate-binding protein 4GBP-4GTP-binding protein 4guanine nucleotide-binding protein 4
Modification date20210518
UniProtAcc

Q96PP9

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
GBP4

GO:0042803

Guanylate-binding protein 4

21151871

GBP4

GO:0005634

Guanylate-binding protein 4

17266443

GBP4

GO:0005634

Guanylate-binding protein 4

21151871

GBP4

GO:0005794

Guanylate-binding protein 4

0000052

GBP4

GO:0005829

Guanylate-binding protein 4

21151871

GBP4

GO:0005886

Guanylate-binding protein 4

0000052

GBP4

GO:0048471

Guanylate-binding protein 4

17266443


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RNA A-to-I events for GBP4

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000162654.8
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_78612(89182510, -), CAediting_78613(89182511, -), CAediting_78614(89182515, -), CAediting_78615(89182517, -), CAediting_78616(89182519, -), CAediting_78617(89182539, -), CAediting_78618(89182554, -), CAediting_78619(89182574, -), CAediting_78620(89182578, -), CAediting_78621(89182579, -), CAediting_78622(89182587, -), CAediting_78623(89182588, -), CAediting_78624(89182590, -), CAediting_78625(89182593, -), CAediting_78626(89182597, -), CAediting_78627(89182603, -), CAediting_78628(89182610, -), CAediting_78629(89182614, -), CAediting_78630(89182620, -), CAediting_78631(89182638, -), CAediting_78632(89182646, -), CAediting_78633(89182649, -), CAediting_78634(89182650, -), CAediting_78635(89182651, -), CAediting_78636(89182652, -), CAediting_78637(89182655, -), CAediting_78638(89182660, -), CAediting_78639(89182664, -), CAediting_78640(89182675, -), CAediting_78641(89182698, -), CAediting_78642(89182706, -), CAediting_78643(89182717, -), CAediting_78644(89182744, -), CAediting_78645(89182747, -), CAediting_78646(89182752, -), CAediting_78647(89183325, -), CAediting_78648(89183621, -), CAediting_78649(89183631, -), CAediting_78650(89183634, -), CAediting_78651(89183644, -), CAediting_78652(89183657, -), CAediting_78653(89183658, -), CAediting_78654(89183661, -), CAediting_78655(89183667, -), CAediting_78656(89183671, -), CAediting_78657(89183674, -), CAediting_78658(89183686, -), CAediting_78659(89183687, -), CAediting_78660(89183710, -), CAediting_78661(89183712, -), CAediting_78662(89183722, -), CAediting_78663(89183732, -), CAediting_78664(89183736, -), CAediting_78665(89183741, -), CAediting_78666(89183748, -), CAediting_78667(89183756, -), CAediting_78668(89183758, -), CAediting_78669(89183768, -), CAediting_78670(89183772, -), CAediting_78671(89183779, -), CAediting_78672(89183780, -), CAediting_78673(89183785, -), CAediting_78674(89183794, -), CAediting_78675(89183797, -), CAediting_78676(89183798, -), CAediting_78677(89183811, -), CAediting_78678(89183812, -), CAediting_78679(89183818, -), CAediting_78680(89183823, -), CAediting_78681(89183833, -), CAediting_78682(89183834, -), CAediting_78683(89183836, -), CAediting_78684(89183839, -), CAediting_78685(89183854, -), CAediting_78686(89183858, -), CAediting_78687(89183866, -), CAediting_78688(89183874, -), CAediting_78689(89183876, -), CAediting_78690(89183877, -), CAediting_78691(89183878, -), CAediting_78692(89184285, -), CAediting_78693(89184308, -), CAediting_78694(89184398, -), CAediting_78695(89184446, -), CAediting_78696(89184481, -), CAediting_78697(89184574, -),

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RNA editing positional annotations for GBP4 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_78612chr1_89182510_-ncRNA_exonic
CAediting_78613chr1_89182511_-ncRNA_exonic
CAediting_78614chr1_89182515_-ncRNA_exonic
CAediting_78615chr1_89182517_-ncRNA_exonic
CAediting_78616chr1_89182519_-ncRNA_exonic
CAediting_78617chr1_89182539_-ncRNA_intronic
CAediting_78618chr1_89182554_-ncRNA_intronic
CAediting_78619chr1_89182574_-ncRNA_intronic
CAediting_78620chr1_89182578_-ncRNA_intronic
CAediting_78621chr1_89182579_-ncRNA_intronic
CAediting_78622chr1_89182587_-ncRNA_intronic
CAediting_78623chr1_89182588_-ncRNA_intronic
CAediting_78624chr1_89182590_-ncRNA_intronic
CAediting_78625chr1_89182593_-ncRNA_intronic
CAediting_78626chr1_89182597_-ncRNA_intronic
CAediting_78627chr1_89182603_-ncRNA_intronic
CAediting_78628chr1_89182610_-ncRNA_intronic
CAediting_78629chr1_89182614_-ncRNA_intronic
CAediting_78630chr1_89182620_-ncRNA_intronic
CAediting_78631chr1_89182638_-ncRNA_intronic
CAediting_78632chr1_89182646_-ncRNA_intronic
CAediting_78633chr1_89182649_-ncRNA_intronic
CAediting_78634chr1_89182650_-ncRNA_intronic
CAediting_78635chr1_89182651_-ncRNA_intronic
CAediting_78636chr1_89182652_-ncRNA_intronic
CAediting_78637chr1_89182655_-ncRNA_intronic
CAediting_78638chr1_89182660_-ncRNA_intronic
CAediting_78639chr1_89182664_-ncRNA_intronic
CAediting_78640chr1_89182675_-ncRNA_intronic
CAediting_78641chr1_89182698_-ncRNA_intronic
CAediting_78642chr1_89182706_-ncRNA_intronic
CAediting_78643chr1_89182717_-ncRNA_intronic
CAediting_78644chr1_89182744_-ncRNA_intronic
CAediting_78645chr1_89182747_-ncRNA_intronic
CAediting_78646chr1_89182752_-ncRNA_intronic
CAediting_78647chr1_89183325_-ncRNA_intronic
CAediting_78648chr1_89183621_-ncRNA_intronic
CAediting_78649chr1_89183631_-ncRNA_intronic
CAediting_78650chr1_89183634_-ncRNA_intronic
CAediting_78651chr1_89183644_-ncRNA_intronic
CAediting_78652chr1_89183657_-ncRNA_intronic
CAediting_78653chr1_89183658_-ncRNA_intronic
CAediting_78654chr1_89183661_-ncRNA_intronic
CAediting_78655chr1_89183667_-ncRNA_intronic
CAediting_78656chr1_89183671_-ncRNA_intronic
CAediting_78657chr1_89183674_-ncRNA_intronic
CAediting_78658chr1_89183686_-ncRNA_intronic
CAediting_78659chr1_89183687_-ncRNA_intronic
CAediting_78660chr1_89183710_-ncRNA_intronic
CAediting_78661chr1_89183712_-ncRNA_intronic
CAediting_78662chr1_89183722_-ncRNA_intronic
CAediting_78663chr1_89183732_-ncRNA_intronic
CAediting_78664chr1_89183736_-ncRNA_intronic
CAediting_78665chr1_89183741_-ncRNA_intronic
CAediting_78666chr1_89183748_-ncRNA_intronic
CAediting_78667chr1_89183756_-ncRNA_intronic
CAediting_78668chr1_89183758_-ncRNA_intronic
CAediting_78669chr1_89183768_-ncRNA_intronic
CAediting_78670chr1_89183772_-ncRNA_intronic
CAediting_78671chr1_89183779_-ncRNA_intronic
CAediting_78672chr1_89183780_-ncRNA_intronic
CAediting_78673chr1_89183785_-ncRNA_intronic
CAediting_78674chr1_89183794_-ncRNA_intronic
CAediting_78675chr1_89183797_-ncRNA_intronic
CAediting_78676chr1_89183798_-ncRNA_intronic
CAediting_78677chr1_89183811_-ncRNA_intronic
CAediting_78678chr1_89183812_-ncRNA_intronic
CAediting_78679chr1_89183818_-ncRNA_intronic
CAediting_78680chr1_89183823_-ncRNA_intronic
CAediting_78681chr1_89183833_-ncRNA_intronic
CAediting_78682chr1_89183834_-ncRNA_intronic
CAediting_78683chr1_89183836_-ncRNA_intronic
CAediting_78684chr1_89183839_-ncRNA_intronic
CAediting_78685chr1_89183854_-ncRNA_intronic
CAediting_78686chr1_89183858_-ncRNA_intronic
CAediting_78687chr1_89183866_-ncRNA_intronic
CAediting_78688chr1_89183874_-ncRNA_intronic
CAediting_78689chr1_89183876_-ncRNA_intronic
CAediting_78690chr1_89183877_-ncRNA_intronic
CAediting_78691chr1_89183878_-ncRNA_intronic
CAediting_78692chr1_89184285_-ncRNA_intronic
CAediting_78693chr1_89184308_-ncRNA_intronic
CAediting_78694chr1_89184398_-ncRNA_intronic
CAediting_78695chr1_89184446_-ncRNA_intronic
CAediting_78696chr1_89184481_-ncRNA_intronic
CAediting_78697chr1_89184574_-ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_78612chr1_89182510_-SINEAluAluYg6
CAediting_78613chr1_89182511_-SINEAluAluYg6
CAediting_78614chr1_89182515_-SINEAluAluYg6
CAediting_78615chr1_89182517_-SINEAluAluYg6
CAediting_78616chr1_89182519_-SINEAluAluYg6
CAediting_78617chr1_89182539_-SINEAluAluYg6
CAediting_78618chr1_89182554_-SINEAluAluYg6
CAediting_78619chr1_89182574_-SINEAluAluYg6
CAediting_78620chr1_89182578_-SINEAluAluYg6
CAediting_78621chr1_89182579_-SINEAluAluYg6
CAediting_78622chr1_89182587_-SINEAluAluYg6
CAediting_78623chr1_89182588_-SINEAluAluYg6
CAediting_78624chr1_89182590_-SINEAluAluYg6
CAediting_78625chr1_89182593_-SINEAluAluYg6
CAediting_78626chr1_89182597_-SINEAluAluYg6
CAediting_78627chr1_89182603_-SINEAluAluYg6
CAediting_78628chr1_89182610_-SINEAluAluYg6
CAediting_78629chr1_89182614_-SINEAluAluYg6
CAediting_78630chr1_89182620_-SINEAluAluYg6
CAediting_78631chr1_89182638_-SINEAluAluYg6
CAediting_78632chr1_89182646_-SINEAluAluYg6
CAediting_78633chr1_89182649_-SINEAluAluYg6
CAediting_78634chr1_89182650_-SINEAluAluYg6
CAediting_78635chr1_89182651_-SINEAluAluYg6
CAediting_78636chr1_89182652_-SINEAluAluYg6
CAediting_78637chr1_89182655_-SINEAluAluYg6
CAediting_78638chr1_89182660_-SINEAluAluYg6
CAediting_78639chr1_89182664_-SINEAluAluYg6
CAediting_78640chr1_89182675_-SINEAluAluYg6
CAediting_78641chr1_89182698_-SINEAluAluYg6
CAediting_78642chr1_89182706_-SINEAluAluYg6
CAediting_78643chr1_89182717_-SINEAluAluYg6
CAediting_78644chr1_89182744_-SINEAluAluYg6
CAediting_78645chr1_89182747_-SINEAluAluYg6
CAediting_78646chr1_89182752_-SINEAluAluYg6
CAediting_78647chr1_89183325_-LINEL1L1PA15
CAediting_78648chr1_89183621_-SINEAluAluJb
CAediting_78649chr1_89183631_-SINEAluAluJb
CAediting_78650chr1_89183634_-SINEAluAluJb
CAediting_78651chr1_89183644_-SINEAluAluJb
CAediting_78652chr1_89183657_-SINEAluAluJb
CAediting_78653chr1_89183658_-SINEAluAluJb
CAediting_78654chr1_89183661_-SINEAluAluJb
CAediting_78655chr1_89183667_-SINEAluAluJb
CAediting_78656chr1_89183671_-SINEAluAluJb
CAediting_78657chr1_89183674_-SINEAluAluJb
CAediting_78658chr1_89183686_-SINEAluAluJb
CAediting_78659chr1_89183687_-SINEAluAluJb
CAediting_78660chr1_89183710_-SINEAluAluJb
CAediting_78661chr1_89183712_-SINEAluAluJb
CAediting_78662chr1_89183722_-SINEAluAluJb
CAediting_78663chr1_89183732_-SINEAluAluJb
CAediting_78664chr1_89183736_-SINEAluAluJb
CAediting_78665chr1_89183741_-SINEAluAluJb
CAediting_78666chr1_89183748_-SINEAluAluJb
CAediting_78667chr1_89183756_-SINEAluAluJb
CAediting_78668chr1_89183758_-SINEAluAluJb
CAediting_78669chr1_89183768_-SINEAluAluJb
CAediting_78670chr1_89183772_-SINEAluAluJb
CAediting_78671chr1_89183779_-SINEAluAluJb
CAediting_78672chr1_89183780_-SINEAluAluJb
CAediting_78673chr1_89183785_-SINEAluAluJb
CAediting_78674chr1_89183794_-SINEAluAluJb
CAediting_78675chr1_89183797_-SINEAluAluJb
CAediting_78676chr1_89183798_-SINEAluAluJb
CAediting_78677chr1_89183811_-SINEAluAluJb
CAediting_78678chr1_89183812_-SINEAluAluJb
CAediting_78679chr1_89183818_-SINEAluAluJb
CAediting_78680chr1_89183823_-SINEAluAluJb
CAediting_78681chr1_89183833_-SINEAluAluJb
CAediting_78682chr1_89183834_-SINEAluAluJb
CAediting_78683chr1_89183836_-SINEAluAluJb
CAediting_78684chr1_89183839_-SINEAluAluJb
CAediting_78685chr1_89183854_-SINEAluAluJb
CAediting_78686chr1_89183858_-SINEAluAluJb
CAediting_78687chr1_89183866_-SINEAluAluJb
CAediting_78688chr1_89183874_-SINEAluAluJb
CAediting_78689chr1_89183876_-SINEAluAluJb
CAediting_78690chr1_89183877_-SINEAluAluJb
CAediting_78691chr1_89183878_-SINEAluAluJb
CAediting_78692chr1_89184285_-LINEL1L1PA15
CAediting_78693chr1_89184308_-LINEL1L1PA15
CAediting_78694chr1_89184398_-LINEL1L1PA15
CAediting_78695chr1_89184446_-LINEL1L1PA15
CAediting_78696chr1_89184481_-LINEL1L1PA15
CAediting_78697chr1_89184574_-LINEL1L1PA15

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RNA A-to-I editing events in the alternative splicing sites for GBP4

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
IRCAediting_78617chr1_89182539_-89182525:891825473SS0+12iATCGCGCCACTGCACTCCAGCCT0.94ATCGCGCCGCTGCACTCCAGCCT1.58
IRCAediting_78688chr1_89183874_-89183870:891838923SS0+2iGTTTTTGTTTTTTGAAACAGGGT8.98GTTTTTGTTTTTTGAAACGGGGT1.02
IRCAediting_78689chr1_89183876_-89183870:891838923SS0+4iGTTTTTGTTTTTTGAAACAGGGT8.98GTTTTTGTTTTTTGAAGCAGGGT5.98
IRCAediting_78690chr1_89183877_-89183870:891838923SS0+5iGTTTTTGTTTTTTGAAACAGGGT8.98GTTTTTGTTTTTTGAGACAGGGT3.26
IRCAediting_78691chr1_89183878_-89183870:891838923SS0+6iGTTTTTGTTTTTTGAAACAGGGT8.98GTTTTTGTTTTTTGGAACAGGGT8.1

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000162654.8.GBP4.
boxplot

check button Correlation between RNA A-to-I editing and PSI for ENSG00000162654.8.GBP4.
boxplot

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for GBP4

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
BLCA.CAediting_78671.ENSG00000162654.GBP4.png
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BRCA.CAediting_78651.ENSG00000162654.GBP4.png
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BRCA.CAediting_78671.ENSG00000162654.GBP4.png
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BRCA.CAediting_78677.ENSG00000162654.GBP4.png
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BRCA.CAediting_78684.ENSG00000162654.GBP4.png
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BRCA.CAediting_78687.ENSG00000162654.GBP4.png
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BRCA.CAediting_78688.ENSG00000162654.GBP4.png
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BRCA.CAediting_78690.ENSG00000162654.GBP4.png
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CESC.CAediting_78671.ENSG00000162654.GBP4.png
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COAD.CAediting_78651.ENSG00000162654.GBP4.png
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COAD.CAediting_78687.ENSG00000162654.GBP4.png
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COAD.CAediting_78688.ENSG00000162654.GBP4.png
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COAD.CAediting_78690.ENSG00000162654.GBP4.png
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GBM.CAediting_78651.ENSG00000162654.GBP4.png
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GBM.CAediting_78684.ENSG00000162654.GBP4.png
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HNSC.CAediting_78671.ENSG00000162654.GBP4.png
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HNSC.CAediting_78687.ENSG00000162654.GBP4.png
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HNSC.CAediting_78688.ENSG00000162654.GBP4.png
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KIRC.CAediting_78642.ENSG00000162654.GBP4.png
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KIRC.CAediting_78651.ENSG00000162654.GBP4.png
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KIRC.CAediting_78690.ENSG00000162654.GBP4.png
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LGG.CAediting_78671.ENSG00000162654.GBP4.png
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LGG.CAediting_78687.ENSG00000162654.GBP4.png
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LGG.CAediting_78690.ENSG00000162654.GBP4.png
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LUAD.CAediting_78687.ENSG00000162654.GBP4.png
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LUAD.CAediting_78688.ENSG00000162654.GBP4.png
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LUAD.CAediting_78690.ENSG00000162654.GBP4.png
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LUSC.CAediting_78671.ENSG00000162654.GBP4.png
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LUSC.CAediting_78687.ENSG00000162654.GBP4.png
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LUSC.CAediting_78690.ENSG00000162654.GBP4.png
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OV.CAediting_78671.ENSG00000162654.GBP4.png
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OV.CAediting_78684.ENSG00000162654.GBP4.png
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OV.CAediting_78687.ENSG00000162654.GBP4.png
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OV.CAediting_78690.ENSG00000162654.GBP4.png
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READ.CAediting_78688.ENSG00000162654.GBP4.png
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READ.CAediting_78690.ENSG00000162654.GBP4.png
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SKCM.CAediting_78671.ENSG00000162654.GBP4.png
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SKCM.CAediting_78687.ENSG00000162654.GBP4.png
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STAD.CAediting_78664.ENSG00000162654.GBP4.png
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STAD.CAediting_78687.ENSG00000162654.GBP4.png
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STAD.CAediting_78688.ENSG00000162654.GBP4.png
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THCA.CAediting_78671.ENSG00000162654.GBP4.png
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THCA.CAediting_78677.ENSG00000162654.GBP4.png
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THCA.CAediting_78687.ENSG00000162654.GBP4.png
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THCA.CAediting_78688.ENSG00000162654.GBP4.png
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THCA.CAediting_78690.ENSG00000162654.GBP4.png
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UCEC.CAediting_78690.ENSG00000162654.GBP4.png
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Protein coding region RNA A-to-I editings for GBP4

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for GBP4

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network
boxplot

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The effects of the RNA editing to the stability of the RNA structures for GBP4

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000355754.6protein_codingSoverviewSoverview
ENST00000481397.1processed_transcriptSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_78612ENST00000355754.6chr1_89182510_--1837.30-1830.90-1947.20
CAediting_78613ENST00000355754.6chr1_89182511_--1830.00-1830.90-1947.20
CAediting_78614ENST00000355754.6chr1_89182515_--1830.10-1830.90-1947.20
CAediting_78615ENST00000355754.6chr1_89182517_--1830.10-1830.90-1947.20
CAediting_78616ENST00000355754.6chr1_89182519_--1831.20-1830.90-1947.20
CAediting_78617ENST00000355754.6chr1_89182539_--1831.20-1830.90-1947.20
CAediting_78618ENST00000355754.6chr1_89182554_--1830.00-1830.90-1947.20
CAediting_78619ENST00000355754.6chr1_89182574_--1834.80-1830.90-1947.20
CAediting_78620ENST00000355754.6chr1_89182578_--1837.60-1830.90-1947.20
CAediting_78621ENST00000355754.6chr1_89182579_--1830.00-1830.90-1947.20
CAediting_78622ENST00000355754.6chr1_89182587_--1831.60-1830.90-1947.20
CAediting_78623ENST00000355754.6chr1_89182588_--1837.80-1830.90-1947.20
CAediting_78624ENST00000355754.6chr1_89182590_--1833.00-1830.90-1947.20
CAediting_78625ENST00000355754.6chr1_89182593_--1834.70-1830.90-1947.20
CAediting_78626ENST00000355754.6chr1_89182597_--1830.00-1830.90-1947.20
CAediting_78627ENST00000355754.6chr1_89182603_--1837.80-1830.90-1947.20
CAediting_78628ENST00000355754.6chr1_89182610_--1830.60-1830.90-1947.20
CAediting_78629ENST00000355754.6chr1_89182614_--1830.20-1830.90-1947.20
CAediting_78630ENST00000355754.6chr1_89182620_--1830.60-1830.90-1947.20
CAediting_78631ENST00000355754.6chr1_89182638_--1830.90-1830.90-1947.20
CAediting_78632ENST00000355754.6chr1_89182646_--1830.50-1830.90-1947.20
CAediting_78633ENST00000355754.6chr1_89182649_--1830.90-1830.90-1947.20
CAediting_78634ENST00000355754.6chr1_89182650_--1831.00-1830.90-1947.20
CAediting_78635ENST00000355754.6chr1_89182651_--1831.00-1830.90-1947.20
CAediting_78636ENST00000355754.6chr1_89182652_--1831.00-1830.90-1947.20
CAediting_78637ENST00000355754.6chr1_89182655_--1830.90-1830.90-1947.20
CAediting_78638ENST00000355754.6chr1_89182660_--1831.20-1830.90-1947.20
CAediting_78639ENST00000355754.6chr1_89182664_--1830.90-1830.90-1947.20
CAediting_78640ENST00000355754.6chr1_89182675_--1830.90-1830.90-1947.20
CAediting_78641ENST00000355754.6chr1_89182698_--1830.30-1830.90-1947.20
CAediting_78642ENST00000355754.6chr1_89182706_--1830.90-1830.90-1947.20
CAediting_78643ENST00000355754.6chr1_89182717_--1834.50-1830.90-1947.20
CAediting_78644ENST00000355754.6chr1_89182744_--1831.20-1830.90-1947.20
CAediting_78645ENST00000355754.6chr1_89182747_--1830.20-1830.90-1947.20
CAediting_78646ENST00000355754.6chr1_89182752_--1830.90-1830.90-1947.20
CAediting_78647ENST00000355754.6chr1_89183325_--1830.70-1830.90-1947.20
CAediting_78648ENST00000355754.6chr1_89183621_--1829.60-1830.90-1947.20
CAediting_78649ENST00000355754.6chr1_89183631_--1837.60-1830.90-1947.20
CAediting_78650ENST00000355754.6chr1_89183634_--1830.60-1830.90-1947.20
CAediting_78651ENST00000355754.6chr1_89183644_--1837.10-1830.90-1947.20
CAediting_78652ENST00000355754.6chr1_89183657_--1831.20-1830.90-1947.20
CAediting_78653ENST00000355754.6chr1_89183658_--1835.10-1830.90-1947.20
CAediting_78654ENST00000355754.6chr1_89183661_--1831.60-1830.90-1947.20
CAediting_78655ENST00000355754.6chr1_89183667_--1830.00-1830.90-1947.20
CAediting_78656ENST00000355754.6chr1_89183671_--1833.50-1830.90-1947.20
CAediting_78657ENST00000355754.6chr1_89183674_--1830.90-1830.90-1947.20
CAediting_78658ENST00000355754.6chr1_89183686_--1837.50-1830.90-1947.20
CAediting_78659ENST00000355754.6chr1_89183687_--1830.90-1830.90-1947.20
CAediting_78660ENST00000355754.6chr1_89183710_--1830.00-1830.90-1947.20
CAediting_78661ENST00000355754.6chr1_89183712_--1830.60-1830.90-1947.20
CAediting_78662ENST00000355754.6chr1_89183722_--1830.90-1830.90-1947.20
CAediting_78663ENST00000355754.6chr1_89183732_--1831.00-1830.90-1947.20
CAediting_78664ENST00000355754.6chr1_89183736_--1837.10-1830.90-1947.20
CAediting_78665ENST00000355754.6chr1_89183741_--1830.90-1830.90-1947.20
CAediting_78666ENST00000355754.6chr1_89183748_--1834.30-1830.90-1947.20
CAediting_78667ENST00000355754.6chr1_89183756_--1830.20-1830.90-1947.20
CAediting_78668ENST00000355754.6chr1_89183758_--1830.90-1830.90-1947.20
CAediting_78669ENST00000355754.6chr1_89183768_--1830.60-1830.90-1947.20
CAediting_78670ENST00000355754.6chr1_89183772_--1834.40-1830.90-1947.20
CAediting_78671ENST00000355754.6chr1_89183779_--1837.60-1830.90-1947.20
CAediting_78672ENST00000355754.6chr1_89183780_--1830.20-1830.90-1947.20
CAediting_78673ENST00000355754.6chr1_89183785_--1834.90-1830.90-1947.20
CAediting_78674ENST00000355754.6chr1_89183794_--1833.50-1830.90-1947.20
CAediting_78675ENST00000355754.6chr1_89183797_--1833.50-1830.90-1947.20
CAediting_78676ENST00000355754.6chr1_89183798_--1831.60-1830.90-1947.20
CAediting_78677ENST00000355754.6chr1_89183811_--1833.10-1830.90-1947.20
CAediting_78678ENST00000355754.6chr1_89183812_--1830.60-1830.90-1947.20
CAediting_78679ENST00000355754.6chr1_89183818_--1829.50-1830.90-1947.20
CAediting_78680ENST00000355754.6chr1_89183823_--1827.50-1830.90-1947.20
CAediting_78681ENST00000355754.6chr1_89183833_--1832.30-1830.90-1947.20
CAediting_78682ENST00000355754.6chr1_89183834_--1836.50-1830.90-1947.20
CAediting_78683ENST00000355754.6chr1_89183836_--1836.30-1830.90-1947.20
CAediting_78684ENST00000355754.6chr1_89183839_--1837.50-1830.90-1947.20
CAediting_78685ENST00000355754.6chr1_89183854_--1830.20-1830.90-1947.20
CAediting_78686ENST00000355754.6chr1_89183858_--1836.30-1830.90-1947.20
CAediting_78687ENST00000355754.6chr1_89183866_--1836.30-1830.90-1947.20
CAediting_78688ENST00000355754.6chr1_89183874_--1837.10-1830.90-1947.20
CAediting_78689ENST00000355754.6chr1_89183876_--1831.20-1830.90-1947.20
CAediting_78690ENST00000355754.6chr1_89183877_--1837.30-1830.90-1947.20
CAediting_78691ENST00000355754.6chr1_89183878_--1830.00-1830.90-1947.20
CAediting_78692ENST00000355754.6chr1_89184285_--1831.10-1830.90-1947.20
CAediting_78693ENST00000355754.6chr1_89184308_--1837.20-1830.90-1947.20
CAediting_78694ENST00000355754.6chr1_89184398_--1832.80-1830.90-1947.20
CAediting_78695ENST00000355754.6chr1_89184446_--1831.90-1830.90-1947.20
CAediting_78696ENST00000355754.6chr1_89184481_--1830.90-1830.90-1947.20
CAediting_78697ENST00000355754.6chr1_89184574_--1831.00-1830.90-1947.20
CAediting_78612ENST00000481397.1chr1_89182510_--110.00-110.00-115.30
CAediting_78613ENST00000481397.1chr1_89182511_--112.00-110.00-115.30
CAediting_78614ENST00000481397.1chr1_89182515_--110.60-110.00-115.30
CAediting_78615ENST00000481397.1chr1_89182517_--112.60-110.00-115.30
CAediting_78616ENST00000481397.1chr1_89182519_--110.30-110.00-115.30

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Relation with ADAR for GBP4

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
STADCAediting_78619chr1_89182574_-....0.01005236559893510.270039922944275
OVCAediting_78619chr1_89182574_-....0.01318608654601640.236760476660941
KIRCCAediting_78620chr1_89182578_-....7.00833370315707e-060.21026910877061
ESCACAediting_78630chr1_89182620_-....0.01921054047816020.237403341326202
BLCACAediting_78642chr1_89182706_-0.0004420709142368880.251136371070715....
LGGCAediting_78642chr1_89182706_-....0.03826882028699560.198764917077909
BRCACAediting_78642chr1_89182706_-0.0002115942764986760.148859905666814....
LIHCCAediting_78642chr1_89182706_-0.0006999007539379140.284120719272282....
CESCCAediting_78642chr1_89182706_-7.35129244953569e-050.280712692551375....
HNSCCAediting_78642chr1_89182706_-0.04700462078819370.126773505205892....
STADCAediting_78642chr1_89182706_-....0.007150680574606950.162157881765165
OVCAediting_78642chr1_89182706_-0.01275111562808080.153692191390042....
PCPGCAediting_78642chr1_89182706_-0.002047275372421830.39673591742214....
SARCCAediting_78642chr1_89182706_-0.014981710949960.214626342099122....
BLCACAediting_78651chr1_89183644_-4.7238127041612e-060.29720117684209....
BRCACAediting_78651chr1_89183644_-8.0550045030646e-180.285361901409931....
LIHCCAediting_78651chr1_89183644_-3.22659522919408e-050.307042741102965....
CESCCAediting_78651chr1_89183644_-2.49666846738864e-060.316161050445226....
LUSCCAediting_78651chr1_89183644_-3.12658238751164e-050.214391028080789....
GBMCAediting_78651chr1_89183644_-0.005863363132463830.277832320440724....
PRADCAediting_78651chr1_89183644_-..0.002193446187321760.182634806163601..
STADCAediting_78651chr1_89183644_-0.006796940545684390.154179909719308....
KIRCCAediting_78651chr1_89183644_-0.0002923916339186160.160683901001218..0.006206602907134940.121749143327943
OVCAediting_78651chr1_89183644_-0.002869754953847530.176300678677869....
SKCMCAediting_78651chr1_89183644_-0.0003341130019604810.206431927260291....
SARCCAediting_78651chr1_89183644_-0.006948589666330750.223260091987156....
BLCACAediting_78658chr1_89183686_-0.002137010654300530.1914411278948660.0003671376364754230.221413865796766..
LGGCAediting_78658chr1_89183686_-....0.02973147273387540.146924407581969
BRCACAediting_78658chr1_89183686_-0.001873525865155350.103921871363991....
LIHCCAediting_78658chr1_89183686_-..0.0359811448038360.160980476119583..
CESCCAediting_78658chr1_89183686_-1.64775909263099e-050.2828841796599750.005377769604978060.184991947025859..
LUADCAediting_78658chr1_89183686_-..0.003249587239119970.139227133702174..
LUSCCAediting_78658chr1_89183686_-0.01376007877510820.1223286675812310.001137507012810940.161137848505303..
GBMCAediting_78658chr1_89183686_-0.0424239707562020.192119428498915....
PRADCAediting_78658chr1_89183686_-..0.0006490538137338030.200826000774323..
HNSCCAediting_78658chr1_89183686_-..7.30610039724709e-060.238467913711763..
STADCAediting_78658chr1_89183686_-..1.5425393507859e-080.299072196720291..
KIRCCAediting_78658chr1_89183686_-..0.0149253825721140.1074227714418650.0007664862558066890.148093042283845
UCECCAediting_78658chr1_89183686_-..0.0003810115311431630.259198775245235..
ESCACAediting_78658chr1_89183686_-0.01637392501609450.204784163307902....
LAMLCAediting_78658chr1_89183686_-..0.0003269711931773590.431953275774816..
OVCAediting_78658chr1_89183686_-0.03640738544275720.1206620209897010.0009158938217984490.190128053864981..
PAADCAediting_78658chr1_89183686_-0.006453169058965730.223712019789330.004674818050933520.23208815939816..
PCPGCAediting_78658chr1_89183686_-0.0008746322526696370.317111372584702....
SKCMCAediting_78658chr1_89183686_-..2.93436300862695e-130.387929761612613..
MESOCAediting_78658chr1_89183686_-..0.009484586078315990.335065242306483..
SARCCAediting_78658chr1_89183686_-..2.10755741834901e-060.363737037005828..
TGCTCAediting_78658chr1_89183686_-..0.000502660690271910.324914419210537..
CESCCAediting_78661chr1_89183712_-0.03224003475902440.21434155387924....
LUSCCAediting_78661chr1_89183712_-0.02166404941350920.192588084397448....
LGGCAediting_78664chr1_89183736_-....0.0389770444890480.229872408402047
KIRCCAediting_78664chr1_89183736_-....0.000684954667138080.169081769366323
LUADCAediting_78665chr1_89183741_-0.03349802501952870.177930705607984....
BLCACAediting_78671chr1_89183779_-0.02080751520362160.138836670170446....
BRCACAediting_78671chr1_89183779_-5.85673922992187e-060.151402883669632....
CESCCAediting_78671chr1_89183779_-0.01434540817024690.165260522054753....
THCACAediting_78671chr1_89183779_-0.001968313621142770.158703754052904....
KIRCCAediting_78671chr1_89183779_-0.03630148824331240.0928220701247641....
SKCMCAediting_78671chr1_89183779_-0.01343965219324890.137419923549597....
TGCTCAediting_78671chr1_89183779_-..0.001461689795695540.297197743828663..
BLCACAediting_78672chr1_89183780_-....0.04546583885921460.161446623404729
LIHCCAediting_78672chr1_89183780_-0.01417427180394170.242222016294332....
STADCAediting_78672chr1_89183780_-..0.03120228677937470.133917260282372..
BLCACAediting_78684chr1_89183839_-1.15995547201885e-050.30457527340623....
LGGCAediting_78684chr1_89183839_-....0.01462145804152570.18123444195066
BRCACAediting_78684chr1_89183839_-7.35899111957375e-090.212951267952972....
CESCCAediting_78684chr1_89183839_-0.01075001058951540.183238061345914....
LUADCAediting_78684chr1_89183839_-0.01667157923769260.12716566456826....
LUSCCAediting_78684chr1_89183839_-0.02186440088908910.125052529810677....
ESCACAediting_78684chr1_89183839_-0.03115847025676770.184226813025884....
BLCACAediting_78687chr1_89183866_-0.008254895119434030.168411064032651....
BRCACAediting_78687chr1_89183866_-0.01296280280928890.0883159264480737....
LUADCAediting_78687chr1_89183866_-0.009041962919762820.131694161645323....
PRADCAediting_78687chr1_89183866_-....0.02990003525144780.154366754516708
LAMLCAediting_78687chr1_89183866_-0.03449477471244250.232404864522545....
SKCMCAediting_78687chr1_89183866_-0.02294915580016120.132843318181067....
SARCCAediting_78687chr1_89183866_-0.0141801849207040.217181944428934....
BLCACAediting_78688chr1_89183874_-0.02688264859637170.156906204231774....
BRCACAediting_78688chr1_89183874_-0.001705670359555340.121707375785823....
CESCCAediting_78688chr1_89183874_-0.00325283762441030.214131107970738....
COADCAediting_78688chr1_89183874_-....0.01609159103093230.181208419117129
STADCAediting_78688chr1_89183874_-0.02245785262528070.126395937366573....
THCACAediting_78688chr1_89183874_-0.02945891700485510.135583998066204....
BLCACAediting_78690chr1_89183877_-0.04701326562251980.143534435238123....
BRCACAediting_78690chr1_89183877_-0.005420885137873370.109550806724702....
KIRCCAediting_78690chr1_89183877_-0.004069045048803620.131309151064119....
SARCCAediting_78690chr1_89183877_-....0.04462928861655690.196411450134786

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Relation with cancer stages for GBP4

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
BLCApathologic_stageCAediting_78620chr1_89182578_-0.01915279067958960.185622899668362
BLCApathologic_stageCAediting_78658chr1_89183686_-0.02697180634013410.138800702123116
BLCApathologic_stageCAediting_78672chr1_89183780_-0.00554228781008410.222514720243513
BLCApathologic_stageCAediting_78690chr1_89183877_-0.005349830033608610.200270239152754
BRCApathologic_stageCAediting_78649chr1_89183631_-0.015895282785626-0.220642043174907
BRCApathologic_stageCAediting_78658chr1_89183686_-0.0114522654209710.0854476149098585
CESCclinical_stageCAediting_78687chr1_89183866_-0.01663585562069080.168328177287653
ESCAclinical_stageCAediting_78661chr1_89183712_-0.0341571124225386-0.51556206901789
HNSCclinical_stageCAediting_78630chr1_89182620_-0.01912504248321580.304282019499937
HNSCclinical_stageCAediting_78672chr1_89183780_-0.03744591128279980.14439546235588
HNSCpathologic_stageCAediting_78630chr1_89182620_-0.04697714611135270.253310484101333
HNSCpathologic_stageCAediting_78632chr1_89182646_-0.02279477270139610.282120166077895
HNSCpathologic_stageCAediting_78642chr1_89182706_-0.005100626652760120.18948670439576
HNSCpathologic_stageCAediting_78672chr1_89183780_-0.001025193903451170.244096362802214
HNSCpathologic_stageCAediting_78684chr1_89183839_-0.04263304002263990.133223642895225
HNSCpathologic_stageCAediting_78690chr1_89183877_-0.02172981078571690.156468473721834
KIRCpathologic_stageCAediting_78642chr1_89182706_-0.001501667961913950.155531171683227
KIRCpathologic_stageCAediting_78649chr1_89183631_-0.04705509894627110.212303202012503
KIRCpathologic_stageCAediting_78651chr1_89183644_-9.16845503007998e-05-0.173687805407534
KIRCpathologic_stageCAediting_78658chr1_89183686_-0.00037742819986108-0.156692063596185
KIRCpathologic_stageCAediting_78671chr1_89183779_-0.002800643890355240.132479279400862
KIRCpathologic_stageCAediting_78686chr1_89183858_-0.03007883058089030.19333421891039
KIRCpathologic_stageCAediting_78687chr1_89183866_-0.00450965970637060.128758230896279
LIHCpathologic_stageCAediting_78672chr1_89183780_-0.03249073508253060.225637424620359
LIHCpathologic_stageCAediting_78687chr1_89183866_-0.04488102441877050.184236003900619
LIHCpathologic_stageCAediting_78688chr1_89183874_-0.03265461031786420.248658800268083
LIHCpathologic_stageCAediting_78690chr1_89183877_-0.01021461361413730.309522608138497
LUADpathologic_stageCAediting_78684chr1_89183839_-0.03205493146369670.114783239574919
LUADpathologic_stageCAediting_78688chr1_89183874_-0.0381145389195520.112349645693737
LUSCpathologic_stageCAediting_78688chr1_89183874_-0.009365074604186680.153143102274317
PAADpathologic_stageCAediting_78642chr1_89182706_-0.02660161130118780.215384034418688
PAADpathologic_stageCAediting_78658chr1_89183686_-0.0336624878628446-0.175329462483581
READpathologic_stageCAediting_78671chr1_89183779_-0.0150910014151173-0.289428170731874
STADpathologic_stageCAediting_78642chr1_89182706_-0.04793202328486930.122325040786539
TGCTclinical_stageCAediting_78651chr1_89183644_-0.037446846243563-0.267091024515219
THCApathologic_stageCAediting_78688chr1_89183874_-0.00242645490644545-0.188740207174898
UCECclinical_stageCAediting_78651chr1_89183644_-0.02619859238410960.176323065749824

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Relation with survival for GBP4

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
BRCACAediting_78684chr1_89183839_-0.01268313607509460.03235130.0551871
LIHCCAediting_78684chr1_89183839_-0.01256212734748910.013407113.421
HNSCCAediting_78687chr1_89183866_-0.02210233726977160.01490117.88925
ESCACAediting_78642chr1_89182706_-0.02943345291073440.026443869.3865
SKCMCAediting_78632chr1_89182646_-0.004634401918510610.04476657.02514e-05
SKCMCAediting_78658chr1_89183686_-0.03451066219852460.04909590.217399
SARCCAediting_78664chr1_89183736_-0.009422901852247480.04255914773.1

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RelatedDrugs for GBP4

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for GBP4

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
GBP4C0023893Liver Cirrhosis, Experimental1CTD_human