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Editing gene: KIF12 (CAeditome ID:113220)

Gene summary for KIF12

Gene summary

Gene information	Gene symbol	KIF12
	Gene ID	113220
	Gene name	kinesin family member 12
	Synonyms	-
	Cytomap	9q32
	Type of gene	protein-coding
	Description	kinesin-like protein KIF12
	Modification date	20210518
	UniProtAcc	Q96FN5
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
KIF12	GO:0070062	Kinesin-like protein KIF12	21082674

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RNA A-to-I events for KIF12

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000136883.11

RNA A-to-I editing events in Cancer.

CAediting_704132(114087372, -), CAediting_704133(114087404, -), CAediting_704134(114087477, -), CAediting_704135(114087500, -), CAediting_704136(114087538, -), CAediting_704137(114087562, -), CAediting_704138(114087563, -), CAediting_704139(114087579, -), CAediting_704140(114087615, -), CAediting_704141(114087623, -), CAediting_704142(114087624, -), CAediting_704143(114087642, -), CAediting_704144(114087687, -), CAediting_704145(114087710, -), CAediting_704146(114090044, -), CAediting_704147(114090051, -), CAediting_704148(114090059, -), CAediting_704149(114090070, -), CAediting_704150(114090079, -), CAediting_704151(114090102, -), CAediting_704152(114090145, -), CAediting_704153(114090159, -), CAediting_704154(114090180, -), CAediting_704155(114090227, -), CAediting_704156(114090474, -), CAediting_704157(114090503, -), CAediting_704158(114090513, -), CAediting_704159(114090517, -), CAediting_704160(114090521, -), CAediting_704161(114090542, -), CAediting_704162(114090551, -), CAediting_704163(114090557, -), CAediting_704164(114090577, -), CAediting_704165(114090601, -), CAediting_704166(114090639, -), CAediting_704167(114090644, -), CAediting_704168(114090649, -), CAediting_704169(114090653, -), CAediting_704170(114090669, -), CAediting_704171(114090753, -), CAediting_704172(114090772, -), CAediting_704173(114090778, -), CAediting_704174(114090779, -), CAediting_704175(114091414, -),

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RNA editing positional annotations for KIF12 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_704132	chr9_114087372_-	ncRNA_intronic
CAediting_704133	chr9_114087404_-	ncRNA_intronic
CAediting_704134	chr9_114087477_-	ncRNA_intronic
CAediting_704135	chr9_114087500_-	ncRNA_intronic
CAediting_704136	chr9_114087538_-	ncRNA_intronic
CAediting_704137	chr9_114087562_-	ncRNA_intronic
CAediting_704138	chr9_114087563_-	ncRNA_intronic
CAediting_704139	chr9_114087579_-	ncRNA_intronic
CAediting_704140	chr9_114087615_-	ncRNA_intronic
CAediting_704141	chr9_114087623_-	ncRNA_intronic
CAediting_704142	chr9_114087624_-	ncRNA_intronic
CAediting_704143	chr9_114087642_-	ncRNA_intronic
CAediting_704144	chr9_114087687_-	ncRNA_intronic
CAediting_704145	chr9_114087710_-	ncRNA_intronic
CAediting_704146	chr9_114090044_-	ncRNA_intronic
CAediting_704147	chr9_114090051_-	ncRNA_intronic
CAediting_704148	chr9_114090059_-	ncRNA_intronic
CAediting_704149	chr9_114090070_-	ncRNA_intronic
CAediting_704150	chr9_114090079_-	ncRNA_intronic
CAediting_704151	chr9_114090102_-	ncRNA_intronic
CAediting_704152	chr9_114090145_-	ncRNA_intronic
CAediting_704153	chr9_114090159_-	ncRNA_intronic
CAediting_704154	chr9_114090180_-	ncRNA_intronic
CAediting_704155	chr9_114090227_-	ncRNA_intronic
CAediting_704156	chr9_114090474_-	ncRNA_intronic
CAediting_704157	chr9_114090503_-	ncRNA_intronic
CAediting_704158	chr9_114090513_-	ncRNA_intronic
CAediting_704159	chr9_114090517_-	ncRNA_intronic
CAediting_704160	chr9_114090521_-	ncRNA_intronic
CAediting_704161	chr9_114090542_-	ncRNA_intronic
CAediting_704162	chr9_114090551_-	ncRNA_intronic
CAediting_704163	chr9_114090557_-	ncRNA_intronic
CAediting_704164	chr9_114090577_-	ncRNA_intronic
CAediting_704165	chr9_114090601_-	ncRNA_intronic
CAediting_704166	chr9_114090639_-	ncRNA_intronic
CAediting_704167	chr9_114090644_-	ncRNA_intronic
CAediting_704168	chr9_114090649_-	ncRNA_intronic
CAediting_704169	chr9_114090653_-	ncRNA_intronic
CAediting_704170	chr9_114090669_-	ncRNA_intronic
CAediting_704171	chr9_114090753_-	ncRNA_intronic
CAediting_704172	chr9_114090772_-	ncRNA_intronic
CAediting_704173	chr9_114090778_-	ncRNA_intronic
CAediting_704174	chr9_114090779_-	ncRNA_intronic
CAediting_704175	chr9_114091414_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_704132	chr9_114087372_-	LTR	ERVL-MaLR	THE1B
CAediting_704133	chr9_114087404_-	LTR	ERVL-MaLR	THE1B
CAediting_704134	chr9_114087477_-	LTR	ERVL-MaLR	THE1B
CAediting_704135	chr9_114087500_-	LTR	ERVL-MaLR	THE1B
CAediting_704136	chr9_114087538_-	LTR	ERVL-MaLR	THE1B
CAediting_704137	chr9_114087562_-	LTR	ERVL-MaLR	THE1B
CAediting_704138	chr9_114087563_-	LTR	ERVL-MaLR	THE1B
CAediting_704139	chr9_114087579_-	LTR	ERVL-MaLR	THE1B
CAediting_704140	chr9_114087615_-	LTR	ERVL-MaLR	THE1B
CAediting_704141	chr9_114087623_-	LTR	ERVL-MaLR	THE1B
CAediting_704142	chr9_114087624_-	LTR	ERVL-MaLR	THE1B
CAediting_704143	chr9_114087642_-	LTR	ERVL-MaLR	THE1B
CAediting_704144	chr9_114087687_-	LTR	ERVL-MaLR	THE1B
CAediting_704145	chr9_114087710_-	LTR	ERVL-MaLR	THE1B
CAediting_704146	chr9_114090044_-	SINE	Alu	AluJo
CAediting_704147	chr9_114090051_-	SINE	Alu	AluJo
CAediting_704148	chr9_114090059_-	SINE	Alu	AluJo
CAediting_704149	chr9_114090070_-	SINE	Alu	AluJo
CAediting_704150	chr9_114090079_-	SINE	Alu	AluJo
CAediting_704151	chr9_114090102_-	SINE	Alu	AluJo
CAediting_704152	chr9_114090145_-	SINE	Alu	AluJo
CAediting_704153	chr9_114090159_-	SINE	Alu	AluJo
CAediting_704154	chr9_114090180_-	SINE	Alu	AluJo
CAediting_704155	chr9_114090227_-	SINE	Alu	AluJo
CAediting_704156	chr9_114090474_-	LTR	ERVL-MaLR	MSTA
CAediting_704157	chr9_114090503_-	LTR	ERVL-MaLR	MSTA
CAediting_704158	chr9_114090513_-	LTR	ERVL-MaLR	MSTA
CAediting_704159	chr9_114090517_-	LTR	ERVL-MaLR	MSTA
CAediting_704160	chr9_114090521_-	LTR	ERVL-MaLR	MSTA
CAediting_704161	chr9_114090542_-	LTR	ERVL-MaLR	MSTA
CAediting_704162	chr9_114090551_-	LTR	ERVL-MaLR	MSTA
CAediting_704163	chr9_114090557_-	LTR	ERVL-MaLR	MSTA
CAediting_704164	chr9_114090577_-	LTR	ERVL-MaLR	MSTA
CAediting_704165	chr9_114090601_-	LTR	ERVL-MaLR	MSTA
CAediting_704166	chr9_114090639_-	LTR	ERVL-MaLR	MSTA
CAediting_704167	chr9_114090644_-	LTR	ERVL-MaLR	MSTA
CAediting_704168	chr9_114090649_-	LTR	ERVL-MaLR	MSTA
CAediting_704169	chr9_114090653_-	LTR	ERVL-MaLR	MSTA
CAediting_704170	chr9_114090669_-	LTR	ERVL-MaLR	MSTA
CAediting_704171	chr9_114090753_-	LTR	ERVL-MaLR	MSTA
CAediting_704172	chr9_114090772_-	LTR	ERVL-MaLR	MSTA
CAediting_704173	chr9_114090778_-	LTR	ERVL-MaLR	MSTA
CAediting_704174	chr9_114090779_-	LTR	ERVL-MaLR	MSTA
CAediting_704175	chr9_114091414_-	SINE	Alu	AluSc5

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RNA A-to-I editing events in the alternative splicing sites for KIF12

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000136883.11.KIF12.

Correlation between RNA A-to-I editing and PSI for ENSG00000136883.11.KIF12.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for KIF12

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for KIF12

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for KIF12

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for KIF12

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for KIF12

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
KIRP	CAediting_704145	chr9_114087710_-	0.0154394629490112	0.340805938168738	.	.	.	.

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Relation with cancer stages for KIF12

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
KIRP	clinical_stage	CAediting_704145	chr9_114087710_-	0.0115710458450997	0.410700905003722

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Relation with survival for KIF12

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for KIF12

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for KIF12

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene