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Editing gene: ATXN2L (CAeditome ID:11273)

Gene summary for ATXN2L

Gene summary

Gene information	Gene symbol	ATXN2L
	Gene ID	11273
	Gene name	ataxin 2 like
	Synonyms	A2D\|A2LG\|A2LP\|A2RP
	Cytomap	16p11.2
	Type of gene	protein-coding
	Description	ataxin-2-like proteinataxin 2 related proteinataxin-2 domain protein
	Modification date	20210529
	UniProtAcc	Q8WWM7
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
ATXN2L	GO:0034063	Ataxin-2-like protein	23209657
ATXN2L	GO:0005829	Ataxin-2-like protein	0000052
ATXN2L	GO:0010494	Ataxin-2-like protein	23209657
ATXN2L	GO:0016020	Ataxin-2-like protein	11784712
ATXN2L	GO:0016607	Ataxin-2-like protein	23209657

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RNA A-to-I events for ATXN2L

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000168488.17

RNA A-to-I editing events in Cancer.

CAediting_1106723(28824967, +), CAediting_1106724(28827170, +), CAediting_1106725(28827178, +), CAediting_1106726(28827184, +), CAediting_1106727(28827195, +), CAediting_1106728(28827200, +), CAediting_1106729(28827224, +), CAediting_1106730(28827313, +), CAediting_1106731(28827319, +), CAediting_1106732(28827330, +), CAediting_1106733(28827336, +), CAediting_1106734(28827337, +), CAediting_1106735(28827354, +), CAediting_1106736(28827374, +), CAediting_1106737(28827405, +), CAediting_1106738(28827616, +), CAediting_1106739(28827638, +), CAediting_1106740(28827661, +), CAediting_1106741(28827685, +), CAediting_1106742(28827795, +), CAediting_1106743(28828285, +), CAediting_1106744(28828331, +), CAediting_1106745(28828332, +), CAediting_1106746(28828353, +), CAediting_1106747(28828372, +), CAediting_1106748(28828397, +), CAediting_1106749(28828400, +), CAediting_1106750(28828401, +), CAediting_1106751(28828410, +), CAediting_1106752(28828422, +), CAediting_1106753(28828425, +), CAediting_1106754(28828426, +), CAediting_1106755(28828428, +), CAediting_1106756(28828434, +), CAediting_1106757(28828435, +), CAediting_1106758(28828436, +), CAediting_1106759(28828439, +), CAediting_1106760(28828455, +), CAediting_1106761(28828471, +), CAediting_1106762(28828492, +), CAediting_1106763(28828506, +), CAediting_1106764(28828507, +), CAediting_1106765(28828532, +), CAediting_1106766(28828536, +), CAediting_1106767(28828537, +), CAediting_1106768(28828539, +), CAediting_1106769(28828566, +), CAediting_1106770(28828577, +), CAediting_1106771(28828768, +), CAediting_1106772(28828780, +), CAediting_1106773(28828825, +), CAediting_1106774(28828830, +), CAediting_1106775(28828849, +), CAediting_1106776(28828855, +), CAediting_1106777(28828856, +), CAediting_1106778(28828877, +), CAediting_1106779(28828885, +), CAediting_1106780(28828909, +), CAediting_1106781(28828917, +), CAediting_1106782(28828923, +), CAediting_1106783(28828926, +), CAediting_1106784(28828928, +), CAediting_1106785(28828991, +), CAediting_1106786(28828993, +), CAediting_1106787(28829005, +), CAediting_1106788(28829007, +), CAediting_1106789(28829011, +), CAediting_1106790(28829018, +), CAediting_1106791(28829021, +), CAediting_1106792(28829066, +), CAediting_1106793(28829075, +), CAediting_1106794(28829081, +), CAediting_1106795(28829082, +), CAediting_1106796(28829095, +), CAediting_1106797(28829125, +), CAediting_1106798(28829132, +), CAediting_1106799(28829136, +), CAediting_1106800(28829144, +), CAediting_1106801(28829148, +), CAediting_1106802(28829152, +), CAediting_1106803(28829160, +), CAediting_1106804(28829186, +), CAediting_1106805(28829193, +), CAediting_1106806(28829223, +), CAediting_1106807(28829224, +), CAediting_1106808(28829237, +), CAediting_1106809(28829268, +), CAediting_1106810(28829277, +),

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RNA editing positional annotations for ATXN2L using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1106723	chr16_28824967_+	ncRNA_intronic
CAediting_1106724	chr16_28827170_+	ncRNA_intronic
CAediting_1106725	chr16_28827178_+	ncRNA_intronic
CAediting_1106726	chr16_28827184_+	ncRNA_intronic
CAediting_1106727	chr16_28827195_+	ncRNA_intronic
CAediting_1106728	chr16_28827200_+	ncRNA_intronic
CAediting_1106729	chr16_28827224_+	ncRNA_intronic
CAediting_1106730	chr16_28827313_+	ncRNA_intronic
CAediting_1106731	chr16_28827319_+	ncRNA_intronic
CAediting_1106732	chr16_28827330_+	ncRNA_intronic
CAediting_1106733	chr16_28827336_+	ncRNA_intronic
CAediting_1106734	chr16_28827337_+	ncRNA_intronic
CAediting_1106735	chr16_28827354_+	ncRNA_intronic
CAediting_1106736	chr16_28827374_+	ncRNA_intronic
CAediting_1106737	chr16_28827405_+	ncRNA_intronic
CAediting_1106738	chr16_28827616_+	ncRNA_intronic
CAediting_1106739	chr16_28827638_+	ncRNA_intronic
CAediting_1106740	chr16_28827661_+	ncRNA_intronic
CAediting_1106741	chr16_28827685_+	ncRNA_intronic
CAediting_1106742	chr16_28827795_+	ncRNA_intronic
CAediting_1106743	chr16_28828285_+	ncRNA_intronic
CAediting_1106744	chr16_28828331_+	ncRNA_intronic
CAediting_1106745	chr16_28828332_+	ncRNA_intronic
CAediting_1106746	chr16_28828353_+	ncRNA_intronic
CAediting_1106747	chr16_28828372_+	ncRNA_intronic
CAediting_1106748	chr16_28828397_+	ncRNA_intronic
CAediting_1106749	chr16_28828400_+	ncRNA_intronic
CAediting_1106750	chr16_28828401_+	ncRNA_intronic
CAediting_1106751	chr16_28828410_+	ncRNA_intronic
CAediting_1106752	chr16_28828422_+	ncRNA_intronic
CAediting_1106753	chr16_28828425_+	ncRNA_intronic
CAediting_1106754	chr16_28828426_+	ncRNA_intronic
CAediting_1106755	chr16_28828428_+	ncRNA_intronic
CAediting_1106756	chr16_28828434_+	ncRNA_intronic
CAediting_1106757	chr16_28828435_+	ncRNA_intronic
CAediting_1106758	chr16_28828436_+	ncRNA_intronic
CAediting_1106759	chr16_28828439_+	ncRNA_intronic
CAediting_1106760	chr16_28828455_+	ncRNA_intronic
CAediting_1106761	chr16_28828471_+	ncRNA_intronic
CAediting_1106762	chr16_28828492_+	ncRNA_intronic
CAediting_1106763	chr16_28828506_+	ncRNA_intronic
CAediting_1106764	chr16_28828507_+	ncRNA_intronic
CAediting_1106765	chr16_28828532_+	ncRNA_intronic
CAediting_1106766	chr16_28828536_+	ncRNA_intronic
CAediting_1106767	chr16_28828537_+	ncRNA_intronic
CAediting_1106768	chr16_28828539_+	ncRNA_intronic
CAediting_1106769	chr16_28828566_+	ncRNA_intronic
CAediting_1106770	chr16_28828577_+	ncRNA_intronic
CAediting_1106771	chr16_28828768_+	ncRNA_intronic
CAediting_1106772	chr16_28828780_+	ncRNA_intronic
CAediting_1106773	chr16_28828825_+	ncRNA_intronic
CAediting_1106774	chr16_28828830_+	ncRNA_intronic
CAediting_1106775	chr16_28828849_+	ncRNA_intronic
CAediting_1106776	chr16_28828855_+	ncRNA_intronic
CAediting_1106777	chr16_28828856_+	ncRNA_intronic
CAediting_1106778	chr16_28828877_+	ncRNA_intronic
CAediting_1106779	chr16_28828885_+	ncRNA_intronic
CAediting_1106780	chr16_28828909_+	ncRNA_intronic
CAediting_1106781	chr16_28828917_+	ncRNA_intronic
CAediting_1106782	chr16_28828923_+	ncRNA_intronic
CAediting_1106783	chr16_28828926_+	ncRNA_intronic
CAediting_1106784	chr16_28828928_+	ncRNA_intronic
CAediting_1106785	chr16_28828991_+	ncRNA_intronic
CAediting_1106786	chr16_28828993_+	ncRNA_intronic
CAediting_1106787	chr16_28829005_+	ncRNA_intronic
CAediting_1106788	chr16_28829007_+	ncRNA_intronic
CAediting_1106789	chr16_28829011_+	ncRNA_intronic
CAediting_1106790	chr16_28829018_+	ncRNA_intronic
CAediting_1106791	chr16_28829021_+	ncRNA_intronic
CAediting_1106792	chr16_28829066_+	ncRNA_intronic
CAediting_1106793	chr16_28829075_+	ncRNA_intronic
CAediting_1106794	chr16_28829081_+	ncRNA_intronic
CAediting_1106795	chr16_28829082_+	ncRNA_intronic
CAediting_1106796	chr16_28829095_+	ncRNA_intronic
CAediting_1106797	chr16_28829125_+	ncRNA_intronic
CAediting_1106798	chr16_28829132_+	ncRNA_intronic
CAediting_1106799	chr16_28829136_+	ncRNA_intronic
CAediting_1106800	chr16_28829144_+	ncRNA_intronic
CAediting_1106801	chr16_28829148_+	ncRNA_intronic
CAediting_1106802	chr16_28829152_+	ncRNA_intronic
CAediting_1106803	chr16_28829160_+	ncRNA_intronic
CAediting_1106804	chr16_28829186_+	ncRNA_intronic
CAediting_1106805	chr16_28829193_+	ncRNA_intronic
CAediting_1106806	chr16_28829223_+	ncRNA_intronic
CAediting_1106807	chr16_28829224_+	ncRNA_intronic
CAediting_1106808	chr16_28829237_+	ncRNA_intronic
CAediting_1106809	chr16_28829268_+	ncRNA_intronic
CAediting_1106810	chr16_28829277_+	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1106723	chr16_28824967_+	SINE	Alu	AluJb
CAediting_1106724	chr16_28827170_+	SINE	Alu	AluJb
CAediting_1106725	chr16_28827178_+	SINE	Alu	AluJb
CAediting_1106726	chr16_28827184_+	SINE	Alu	AluJb
CAediting_1106727	chr16_28827195_+	SINE	Alu	AluJb
CAediting_1106728	chr16_28827200_+	SINE	Alu	AluJb
CAediting_1106729	chr16_28827224_+	SINE	Alu	AluJb
CAediting_1106730	chr16_28827313_+	SINE	Alu	AluJb
CAediting_1106731	chr16_28827319_+	SINE	Alu	AluJb
CAediting_1106732	chr16_28827330_+	SINE	Alu	AluJb
CAediting_1106733	chr16_28827336_+	SINE	Alu	AluJb
CAediting_1106734	chr16_28827337_+	SINE	Alu	AluJb
CAediting_1106735	chr16_28827354_+	SINE	Alu	AluJb
CAediting_1106736	chr16_28827374_+	SINE	Alu	AluJb
CAediting_1106737	chr16_28827405_+	SINE	Alu	AluJb
CAediting_1106738	chr16_28827616_+	SINE	Alu	AluJo
CAediting_1106739	chr16_28827638_+	SINE	Alu	AluJo
CAediting_1106740	chr16_28827661_+	SINE	Alu	AluJo
CAediting_1106741	chr16_28827685_+	SINE	Alu	AluJo
CAediting_1106742	chr16_28827795_+	SINE	Alu	FAM
CAediting_1106744	chr16_28828331_+	SINE	Alu	AluSp
CAediting_1106745	chr16_28828332_+	SINE	Alu	AluSp
CAediting_1106746	chr16_28828353_+	SINE	Alu	AluSp
CAediting_1106747	chr16_28828372_+	SINE	Alu	AluSp
CAediting_1106748	chr16_28828397_+	SINE	Alu	AluSp
CAediting_1106749	chr16_28828400_+	SINE	Alu	AluSp
CAediting_1106750	chr16_28828401_+	SINE	Alu	AluSp
CAediting_1106751	chr16_28828410_+	SINE	Alu	AluSp
CAediting_1106752	chr16_28828422_+	SINE	Alu	AluSp
CAediting_1106753	chr16_28828425_+	SINE	Alu	AluSp
CAediting_1106754	chr16_28828426_+	SINE	Alu	AluSp
CAediting_1106755	chr16_28828428_+	SINE	Alu	AluSp
CAediting_1106756	chr16_28828434_+	SINE	Alu	AluSp
CAediting_1106757	chr16_28828435_+	SINE	Alu	AluSp
CAediting_1106758	chr16_28828436_+	SINE	Alu	AluSp
CAediting_1106759	chr16_28828439_+	SINE	Alu	AluSp
CAediting_1106760	chr16_28828455_+	SINE	Alu	AluSp
CAediting_1106761	chr16_28828471_+	SINE	Alu	AluSp
CAediting_1106762	chr16_28828492_+	SINE	Alu	AluSp
CAediting_1106763	chr16_28828506_+	SINE	Alu	AluSp
CAediting_1106764	chr16_28828507_+	SINE	Alu	AluSp
CAediting_1106765	chr16_28828532_+	SINE	Alu	AluSp
CAediting_1106766	chr16_28828536_+	SINE	Alu	AluSp
CAediting_1106767	chr16_28828537_+	SINE	Alu	AluSp
CAediting_1106768	chr16_28828539_+	SINE	Alu	AluSp
CAediting_1106769	chr16_28828566_+	SINE	Alu	AluSp
CAediting_1106770	chr16_28828577_+	SINE	Alu	AluSp
CAediting_1106771	chr16_28828768_+	SINE	Alu	AluSx
CAediting_1106772	chr16_28828780_+	SINE	Alu	AluSx
CAediting_1106773	chr16_28828825_+	SINE	Alu	AluSx
CAediting_1106774	chr16_28828830_+	SINE	Alu	AluSx
CAediting_1106775	chr16_28828849_+	SINE	Alu	AluSx
CAediting_1106776	chr16_28828855_+	SINE	Alu	AluSx
CAediting_1106777	chr16_28828856_+	SINE	Alu	AluSx
CAediting_1106778	chr16_28828877_+	SINE	Alu	AluSx
CAediting_1106779	chr16_28828885_+	SINE	Alu	AluSx
CAediting_1106780	chr16_28828909_+	SINE	Alu	AluSx
CAediting_1106781	chr16_28828917_+	SINE	Alu	AluSx
CAediting_1106782	chr16_28828923_+	SINE	Alu	AluSx
CAediting_1106783	chr16_28828926_+	SINE	Alu	AluSx
CAediting_1106784	chr16_28828928_+	SINE	Alu	AluSx
CAediting_1106785	chr16_28828991_+	SINE	Alu	AluSx
CAediting_1106786	chr16_28828993_+	SINE	Alu	AluSx
CAediting_1106787	chr16_28829005_+	SINE	Alu	AluSx
CAediting_1106788	chr16_28829007_+	SINE	Alu	AluSx
CAediting_1106789	chr16_28829011_+	SINE	Alu	AluSx
CAediting_1106790	chr16_28829018_+	SINE	Alu	AluSx
CAediting_1106791	chr16_28829021_+	SINE	Alu	AluSx
CAediting_1106792	chr16_28829066_+	SINE	Alu	AluJr
CAediting_1106793	chr16_28829075_+	SINE	Alu	AluJr
CAediting_1106794	chr16_28829081_+	SINE	Alu	AluJr
CAediting_1106795	chr16_28829082_+	SINE	Alu	AluJr
CAediting_1106796	chr16_28829095_+	SINE	Alu	AluJr
CAediting_1106797	chr16_28829125_+	SINE	Alu	AluJr
CAediting_1106798	chr16_28829132_+	SINE	Alu	AluJr
CAediting_1106799	chr16_28829136_+	SINE	Alu	AluJr
CAediting_1106800	chr16_28829144_+	SINE	Alu	AluJr
CAediting_1106801	chr16_28829148_+	SINE	Alu	AluJr
CAediting_1106802	chr16_28829152_+	SINE	Alu	AluJr
CAediting_1106803	chr16_28829160_+	SINE	Alu	AluJr
CAediting_1106804	chr16_28829186_+	SINE	Alu	AluJr
CAediting_1106805	chr16_28829193_+	SINE	Alu	AluJr
CAediting_1106806	chr16_28829223_+	SINE	Alu	AluJr
CAediting_1106807	chr16_28829224_+	SINE	Alu	AluJr
CAediting_1106808	chr16_28829237_+	SINE	Alu	AluJr
CAediting_1106809	chr16_28829268_+	SINE	Alu	AluJr
CAediting_1106810	chr16_28829277_+	SINE	Alu	AluJr

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RNA A-to-I editing events in the alternative splicing sites for ATXN2L

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000168488.17.ATXN2L.

Correlation between RNA A-to-I editing and PSI for ENSG00000168488.17.ATXN2L.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ATXN2L

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

LAML.CAediting_1106782.ENSG00000168488.ATXN2L.png
Soverview

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Protein coding region RNA A-to-I editings for ATXN2L

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for ATXN2L

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_748296	chr10_51299626_+	ENSG00000168488.17	ENST00000340394	hsa-miR-605-3p	28837006	28837012	7mer-m8	28836991	28837013	142	-15.89
CAediting_748296	chr10_51299626_+	ENSG00000168488.17	ENST00000325215	hsa-miR-605-3p	28837006	28837012	7mer-m8	28836991	28837013	142	-15.89
CAediting_748296	chr10_51299626_+	ENSG00000168488.17	ENST00000336783	hsa-miR-605-3p	28837006	28837012	7mer-m8	28836991	28837013	142	-15.89
CAediting_748296	chr10_51299626_+	ENSG00000168488.17	ENST00000382686	hsa-miR-605-3p	28837006	28837012	7mer-m8	28836991	28837013	142	-15.89
CAediting_748296	chr10_51299626_+	ENSG00000168488.17	ENST00000395547	hsa-miR-605-3p	28837006	28837012	7mer-m8	28836991	28837013	142	-15.89
CAediting_748296	chr10_51299626_+	ENSG00000168488.17	ENST00000570200	hsa-miR-605-3p	28837006	28837012	7mer-m8	28836991	28837013	142	-15.89
CAediting_748296	chr10_51299626_+	ENSG00000168488.17	ENST00000565971	hsa-miR-605-3p	28837006	28837012	7mer-m8	28836991	28837013	142	-15.89
CAediting_748296	chr10_51299626_+	ENSG00000168488.17	ENST00000566946	hsa-miR-605-3p	28837006	28837012	7mer-m8	28836991	28837013	142	-15.89
CAediting_748296	chr10_51299626_+	ENSG00000168488.17	ENST00000562583	hsa-miR-605-3p	28837006	28837012	7mer-m8	28836991	28837013	142	-15.89
CAediting_748296	chr10_51299626_+	ENSG00000168488.17	ENST00000564162	hsa-miR-605-3p	28837006	28837012	7mer-m8	28836991	28837013	142	-15.89
CAediting_748296	chr10_51299626_+	ENSG00000168488.17	ENST00000567024	hsa-miR-605-3p	28837006	28837012	7mer-m8	28836991	28837013	142	-15.89
CAediting_1351755	chr19_40282625_-	ENSG00000168488.17	ENST00000340394	hsa-miR-641	28836830	28836836	7mer-m8	28836814	28836837	154	-24.5
CAediting_86358	chr1_109598906_+	ENSG00000168488.17	ENST00000340394	hsa-miR-197-5p	28836995	28837001	7mer-1a	28836978	28837001	148	-35.62
CAediting_604450	chr7_133034877_-	ENSG00000168488.17	ENST00000340394	hsa-miR-3654	28836952	28836959	8mer-1a	28836941	28836959	140	-17.53
CAediting_524911	chr7_5495852_-	ENSG00000168488.17	ENST00000340394	hsa-miR-589-3p	28836975	28836981	7mer-m8	28836957	28836982	152	-22.5
CAediting_1351755	chr19_40282625_-	ENSG00000168488.17	ENST00000325215	hsa-miR-641	28836830	28836836	7mer-m8	28836814	28836837	154	-24.5
CAediting_86358	chr1_109598906_+	ENSG00000168488.17	ENST00000325215	hsa-miR-197-5p	28836995	28837001	7mer-1a	28836978	28837001	148	-35.62
CAediting_604450	chr7_133034877_-	ENSG00000168488.17	ENST00000325215	hsa-miR-3654	28836952	28836959	8mer-1a	28836941	28836959	140	-17.53
CAediting_524911	chr7_5495852_-	ENSG00000168488.17	ENST00000325215	hsa-miR-589-3p	28836975	28836981	7mer-m8	28836957	28836982	152	-22.5
CAediting_1351755	chr19_40282625_-	ENSG00000168488.17	ENST00000336783	hsa-miR-641	28836830	28836836	7mer-m8	28836814	28836837	154	-24.5
CAediting_1368054	chr19_46709310_-	ENSG00000168488.17	ENST00000336783	hsa-miR-320e	28836444	28836450	7mer-m8	28836436	28836451	147	-20.14
CAediting_86358	chr1_109598906_+	ENSG00000168488.17	ENST00000336783	hsa-miR-197-5p	28836757	28836763	7mer-m8	28836739	28836764	163	-35.33
CAediting_86358	chr1_109598906_+	ENSG00000168488.17	ENST00000336783	hsa-miR-197-5p	28836995	28837001	7mer-1a	28836978	28837001	148	-35.62
CAediting_604450	chr7_133034877_-	ENSG00000168488.17	ENST00000336783	hsa-miR-3654	28836952	28836959	8mer-1a	28836941	28836959	140	-17.53
CAediting_524911	chr7_5495852_-	ENSG00000168488.17	ENST00000336783	hsa-miR-589-3p	28836975	28836981	7mer-m8	28836957	28836982	152	-22.5
CAediting_1351755	chr19_40282625_-	ENSG00000168488.17	ENST00000382686	hsa-miR-641	28836830	28836836	7mer-m8	28836814	28836837	154	-24.5
CAediting_86358	chr1_109598906_+	ENSG00000168488.17	ENST00000382686	hsa-miR-197-5p	28836995	28837001	7mer-1a	28836978	28837001	148	-35.62
CAediting_604450	chr7_133034877_-	ENSG00000168488.17	ENST00000382686	hsa-miR-3654	28836952	28836959	8mer-1a	28836941	28836959	140	-17.53
CAediting_524911	chr7_5495852_-	ENSG00000168488.17	ENST00000382686	hsa-miR-589-3p	28836975	28836981	7mer-m8	28836957	28836982	152	-22.5
CAediting_1351755	chr19_40282625_-	ENSG00000168488.17	ENST00000395547	hsa-miR-641	28836830	28836836	7mer-m8	28836814	28836837	154	-24.5
CAediting_86358	chr1_109598906_+	ENSG00000168488.17	ENST00000395547	hsa-miR-197-5p	28836995	28837001	7mer-1a	28836978	28837001	148	-35.62
CAediting_86358	chr1_109598906_+	ENSG00000168488.17	ENST00000395547	hsa-miR-197-5p	28836757	28836763	7mer-m8	28836739	28836764	163	-35.33
CAediting_604450	chr7_133034877_-	ENSG00000168488.17	ENST00000395547	hsa-miR-3654	28836952	28836959	8mer-1a	28836941	28836959	140	-17.53
CAediting_524911	chr7_5495852_-	ENSG00000168488.17	ENST00000395547	hsa-miR-589-3p	28836975	28836981	7mer-m8	28836957	28836982	152	-22.5
CAediting_1351755	chr19_40282625_-	ENSG00000168488.17	ENST00000564304	hsa-miR-641	28836830	28836836	7mer-m8	28836814	28836837	154	-24.5
CAediting_1351755	chr19_40282625_-	ENSG00000168488.17	ENST00000570200	hsa-miR-641	28836830	28836836	7mer-m8	28836814	28836837	154	-24.5
CAediting_86358	chr1_109598906_+	ENSG00000168488.17	ENST00000570200	hsa-miR-197-5p	28836995	28837001	7mer-1a	28836978	28837001	148	-35.62
CAediting_604450	chr7_133034877_-	ENSG00000168488.17	ENST00000570200	hsa-miR-3654	28836952	28836959	8mer-1a	28836941	28836959	140	-17.53
CAediting_524911	chr7_5495852_-	ENSG00000168488.17	ENST00000570200	hsa-miR-589-3p	28836975	28836981	7mer-m8	28836957	28836982	152	-22.5
CAediting_1399425	chr20_1392958_-	ENSG00000168488.17	ENST00000565971	hsa-miR-6869-5p	28835293	28835299	7mer-m8	28835277	28835300	151	-25.3
CAediting_1054808	chr15_66496985_-	ENSG00000168488.17	ENST00000565971	hsa-miR-4512	28835562	28835568	7mer-1a	28835548	28835568	147	-23.63
CAediting_1351755	chr19_40282625_-	ENSG00000168488.17	ENST00000565971	hsa-miR-641	28836830	28836836	7mer-m8	28836814	28836837	154	-24.5
CAediting_1368054	chr19_46709310_-	ENSG00000168488.17	ENST00000565971	hsa-miR-320e	28836444	28836450	7mer-m8	28836436	28836451	147	-20.14
CAediting_86358	chr1_109598906_+	ENSG00000168488.17	ENST00000565971	hsa-miR-197-5p	28836995	28837001	7mer-1a	28836978	28837001	148	-35.62
CAediting_86358	chr1_109598906_+	ENSG00000168488.17	ENST00000565971	hsa-miR-197-5p	28836757	28836763	7mer-m8	28836739	28836764	163	-35.33
CAediting_604450	chr7_133034877_-	ENSG00000168488.17	ENST00000565971	hsa-miR-3654	28836952	28836959	8mer-1a	28836941	28836959	140	-17.53
CAediting_524911	chr7_5495852_-	ENSG00000168488.17	ENST00000565971	hsa-miR-589-3p	28836975	28836981	7mer-m8	28836957	28836982	152	-22.5
CAediting_1351755	chr19_40282625_-	ENSG00000168488.17	ENST00000566946	hsa-miR-641	28836830	28836836	7mer-m8	28836814	28836837	154	-24.5
CAediting_1368054	chr19_46709310_-	ENSG00000168488.17	ENST00000566946	hsa-miR-320e	28836444	28836450	7mer-m8	28836436	28836451	147	-20.14
CAediting_86358	chr1_109598906_+	ENSG00000168488.17	ENST00000566946	hsa-miR-197-5p	28836757	28836763	7mer-m8	28836739	28836764	163	-35.33
CAediting_86358	chr1_109598906_+	ENSG00000168488.17	ENST00000566946	hsa-miR-197-5p	28836995	28837001	7mer-1a	28836978	28837001	148	-35.62
CAediting_604450	chr7_133034877_-	ENSG00000168488.17	ENST00000566946	hsa-miR-3654	28836952	28836959	8mer-1a	28836941	28836959	140	-17.53
CAediting_524911	chr7_5495852_-	ENSG00000168488.17	ENST00000566946	hsa-miR-589-3p	28836975	28836981	7mer-m8	28836957	28836982	152	-22.5
CAediting_1368054	chr19_46709310_-	ENSG00000168488.17	ENST00000562583	hsa-miR-320e	28836444	28836450	7mer-m8	28836436	28836451	147	-20.14
CAediting_1351755	chr19_40282625_-	ENSG00000168488.17	ENST00000562583	hsa-miR-641	28836830	28836836	7mer-m8	28836814	28836837	154	-24.5
CAediting_86358	chr1_109598906_+	ENSG00000168488.17	ENST00000562583	hsa-miR-197-5p	28836995	28837001	7mer-1a	28836978	28837001	148	-35.62
CAediting_86358	chr1_109598906_+	ENSG00000168488.17	ENST00000562583	hsa-miR-197-5p	28836757	28836763	7mer-m8	28836739	28836764	163	-35.33
CAediting_604450	chr7_133034877_-	ENSG00000168488.17	ENST00000562583	hsa-miR-3654	28836952	28836959	8mer-1a	28836941	28836959	140	-17.53
CAediting_524911	chr7_5495852_-	ENSG00000168488.17	ENST00000562583	hsa-miR-589-3p	28836975	28836981	7mer-m8	28836957	28836982	152	-22.5
CAediting_1351755	chr19_40282625_-	ENSG00000168488.17	ENST00000564162	hsa-miR-641	28836830	28836836	7mer-m8	28836814	28836837	154	-24.5
CAediting_86358	chr1_109598906_+	ENSG00000168488.17	ENST00000564162	hsa-miR-197-5p	28836995	28837001	7mer-1a	28836978	28837001	148	-35.62
CAediting_604450	chr7_133034877_-	ENSG00000168488.17	ENST00000564162	hsa-miR-3654	28836952	28836959	8mer-1a	28836941	28836959	140	-17.53
CAediting_524911	chr7_5495852_-	ENSG00000168488.17	ENST00000564162	hsa-miR-589-3p	28836975	28836981	7mer-m8	28836957	28836982	152	-22.5
CAediting_1351755	chr19_40282625_-	ENSG00000168488.17	ENST00000567024	hsa-miR-641	28836830	28836836	7mer-m8	28836814	28836837	154	-24.5
CAediting_86358	chr1_109598906_+	ENSG00000168488.17	ENST00000567024	hsa-miR-197-5p	28836995	28837001	7mer-1a	28836978	28837001	148	-35.62
CAediting_604450	chr7_133034877_-	ENSG00000168488.17	ENST00000567024	hsa-miR-3654	28836952	28836959	8mer-1a	28836941	28836959	140	-17.53
CAediting_524911	chr7_5495852_-	ENSG00000168488.17	ENST00000567024	hsa-miR-589-3p	28836975	28836981	7mer-m8	28836957	28836982	152	-22.5

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_980496	chr14_31014685_-	ENSG00000168488.17	ENST00000565971	hsa-miR-624-3p	28833276	28833282	7mer-m8	28833263	28833283	149	-12.56

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ATXN2L

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for ATXN2L

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for ATXN2L

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
ESCA	pathologic_stage	CAediting_1106799	chr16_28829136_+	0.0184380193865469	0.281037410934611

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Relation with survival for ATXN2L

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for ATXN2L

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for ATXN2L

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene