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Editing gene: CHM (CAeditome ID:1121)

Gene summary for CHM

Gene summary

Gene information	Gene symbol	CHM
	Gene ID	1121
	Gene name	CHM Rab escort protein
	Synonyms	DXS540\|GGTA\|HSD-32\|REP-1\|TCD
	Cytomap	Xq21.2
	Type of gene	protein-coding
	Description	rab proteins geranylgeranyltransferase component A 1CHM, Rab escort protein 1choroideremia (Rab escort protein 1)
	Modification date	20210518
	UniProtAcc	P24386
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
CHM	GO:0031267	Rab proteins geranylgeranyltransferase component A 1	7957092
CHM	GO:0018344	Rab proteins geranylgeranyltransferase component A 1	7957092
CHM	GO:0005968	Rab proteins geranylgeranyltransferase component A 1	7957092

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RNA A-to-I events for CHM

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000188419.12

RNA A-to-I editing events in Cancer.

CAediting_1515680(85863120, -), CAediting_1515681(85863122, -), CAediting_1515682(85863123, -), CAediting_1515683(85863160, -), CAediting_1515684(85863161, -), CAediting_1515685(85863186, -), CAediting_1515686(85863189, -), CAediting_1515687(85863190, -), CAediting_1515688(85863245, -), CAediting_1515689(85863256, -), CAediting_1515690(85863262, -), CAediting_1515691(85863264, -), CAediting_1515692(85863266, -), CAediting_1515693(85863268, -), CAediting_1515694(85863269, -), CAediting_1515695(85863275, -), CAediting_1515696(85863286, -), CAediting_1515697(85863296, -), CAediting_1515698(85863306, -), CAediting_1515699(85863317, -), CAediting_1515700(85863335, -), CAediting_1515701(85863348, -), CAediting_1515702(85863349, -), CAediting_1515703(85863366, -), CAediting_1515704(85935450, -), CAediting_1515705(85935478, -), CAediting_1515706(85935496, -), CAediting_1515707(85935594, -), CAediting_1515708(85938978, -), CAediting_1515709(85938994, -), CAediting_1515710(85939153, -), CAediting_1515711(85939173, -), CAediting_1515712(85939182, -), CAediting_1515713(85939191, -), CAediting_1515714(85947504, -), CAediting_1515715(85960644, -), CAediting_1515716(86017622, -), CAediting_1515717(86017670, -), CAediting_1515718(86025422, -), CAediting_1515719(86025501, -), CAediting_1515720(86025510, -), CAediting_1515721(86025555, -), CAediting_1515722(86025561, -), CAediting_1515723(86025565, -), CAediting_1515724(86025641, -), CAediting_1515725(86026150, -), CAediting_1515726(86026166, -), CAediting_1515727(86026169, -), CAediting_1515728(86026180, -), CAediting_1515729(86026192, -), CAediting_1515730(86026193, -), CAediting_1515731(86026256, -), CAediting_1515732(86026261, -), CAediting_1515733(86026262, -), CAediting_1515734(86026288, -), CAediting_1515735(86026300, -), CAediting_1515736(86026303, -), CAediting_1515737(86026328, -), CAediting_1515738(86026337, -), CAediting_1515739(86026359, -), CAediting_1515740(86026403, -), CAediting_1515741(86026412, -), CAediting_1515742(86026426, -), CAediting_1515743(86035932, -), CAediting_1515744(86037316, -), CAediting_1515745(86037336, -),

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RNA editing positional annotations for CHM using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1515680	chrX_85863120_-	ncRNA_intronic
CAediting_1515681	chrX_85863122_-	ncRNA_intronic
CAediting_1515682	chrX_85863123_-	ncRNA_intronic
CAediting_1515683	chrX_85863160_-	ncRNA_intronic
CAediting_1515684	chrX_85863161_-	ncRNA_intronic
CAediting_1515685	chrX_85863186_-	ncRNA_intronic
CAediting_1515686	chrX_85863189_-	ncRNA_intronic
CAediting_1515687	chrX_85863190_-	ncRNA_intronic
CAediting_1515688	chrX_85863245_-	ncRNA_intronic
CAediting_1515689	chrX_85863256_-	ncRNA_intronic
CAediting_1515690	chrX_85863262_-	ncRNA_intronic
CAediting_1515691	chrX_85863264_-	ncRNA_intronic
CAediting_1515692	chrX_85863266_-	ncRNA_intronic
CAediting_1515693	chrX_85863268_-	ncRNA_intronic
CAediting_1515694	chrX_85863269_-	ncRNA_intronic
CAediting_1515695	chrX_85863275_-	ncRNA_intronic
CAediting_1515696	chrX_85863286_-	ncRNA_intronic
CAediting_1515697	chrX_85863296_-	ncRNA_intronic
CAediting_1515698	chrX_85863306_-	ncRNA_intronic
CAediting_1515699	chrX_85863317_-	ncRNA_intronic
CAediting_1515700	chrX_85863335_-	ncRNA_intronic
CAediting_1515701	chrX_85863348_-	ncRNA_intronic
CAediting_1515702	chrX_85863349_-	ncRNA_intronic
CAediting_1515703	chrX_85863366_-	ncRNA_intronic
CAediting_1515704	chrX_85935450_-	ncRNA_intronic
CAediting_1515705	chrX_85935478_-	ncRNA_intronic
CAediting_1515706	chrX_85935496_-	ncRNA_intronic
CAediting_1515707	chrX_85935594_-	ncRNA_intronic
CAediting_1515708	chrX_85938978_-	ncRNA_intronic
CAediting_1515709	chrX_85938994_-	ncRNA_intronic
CAediting_1515710	chrX_85939153_-	ncRNA_intronic
CAediting_1515711	chrX_85939173_-	ncRNA_intronic
CAediting_1515712	chrX_85939182_-	ncRNA_intronic
CAediting_1515713	chrX_85939191_-	ncRNA_intronic
CAediting_1515714	chrX_85947504_-	ncRNA_intronic
CAediting_1515715	chrX_85960644_-	ncRNA_intronic
CAediting_1515716	chrX_86017622_-	ncRNA_intronic
CAediting_1515717	chrX_86017670_-	ncRNA_intronic
CAediting_1515718	chrX_86025422_-	ncRNA_intronic
CAediting_1515719	chrX_86025501_-	ncRNA_intronic
CAediting_1515720	chrX_86025510_-	ncRNA_intronic
CAediting_1515721	chrX_86025555_-	ncRNA_intronic
CAediting_1515722	chrX_86025561_-	ncRNA_intronic
CAediting_1515723	chrX_86025565_-	ncRNA_intronic
CAediting_1515724	chrX_86025641_-	ncRNA_intronic
CAediting_1515725	chrX_86026150_-	ncRNA_intronic
CAediting_1515726	chrX_86026166_-	ncRNA_intronic
CAediting_1515727	chrX_86026169_-	ncRNA_intronic
CAediting_1515728	chrX_86026180_-	ncRNA_intronic
CAediting_1515729	chrX_86026192_-	ncRNA_intronic
CAediting_1515730	chrX_86026193_-	ncRNA_intronic
CAediting_1515731	chrX_86026256_-	ncRNA_intronic
CAediting_1515732	chrX_86026261_-	ncRNA_intronic
CAediting_1515733	chrX_86026262_-	ncRNA_intronic
CAediting_1515734	chrX_86026288_-	ncRNA_intronic
CAediting_1515735	chrX_86026300_-	ncRNA_intronic
CAediting_1515736	chrX_86026303_-	ncRNA_intronic
CAediting_1515737	chrX_86026328_-	ncRNA_intronic
CAediting_1515738	chrX_86026337_-	ncRNA_intronic
CAediting_1515739	chrX_86026359_-	ncRNA_intronic
CAediting_1515740	chrX_86026403_-	ncRNA_intronic
CAediting_1515741	chrX_86026412_-	ncRNA_intronic
CAediting_1515742	chrX_86026426_-	ncRNA_intronic
CAediting_1515743	chrX_86035932_-	ncRNA_intronic
CAediting_1515744	chrX_86037316_-	ncRNA_intronic
CAediting_1515745	chrX_86037336_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1515680	chrX_85863120_-	SINE	Alu	AluSx1
CAediting_1515681	chrX_85863122_-	SINE	Alu	AluSx1
CAediting_1515682	chrX_85863123_-	SINE	Alu	AluSx1
CAediting_1515683	chrX_85863160_-	SINE	Alu	AluSx1
CAediting_1515684	chrX_85863161_-	SINE	Alu	AluSx1
CAediting_1515685	chrX_85863186_-	SINE	Alu	AluSx1
CAediting_1515686	chrX_85863189_-	SINE	Alu	AluSx1
CAediting_1515687	chrX_85863190_-	SINE	Alu	AluSx1
CAediting_1515688	chrX_85863245_-	SINE	Alu	AluSx1
CAediting_1515689	chrX_85863256_-	SINE	Alu	AluSx1
CAediting_1515690	chrX_85863262_-	SINE	Alu	AluSx1
CAediting_1515691	chrX_85863264_-	SINE	Alu	AluSx1
CAediting_1515692	chrX_85863266_-	SINE	Alu	AluSx1
CAediting_1515693	chrX_85863268_-	SINE	Alu	AluSx1
CAediting_1515694	chrX_85863269_-	SINE	Alu	AluSx1
CAediting_1515695	chrX_85863275_-	SINE	Alu	AluSx1
CAediting_1515696	chrX_85863286_-	SINE	Alu	AluSx1
CAediting_1515697	chrX_85863296_-	SINE	Alu	AluSx1
CAediting_1515698	chrX_85863306_-	SINE	Alu	AluSx1
CAediting_1515699	chrX_85863317_-	SINE	Alu	AluSx1
CAediting_1515700	chrX_85863335_-	SINE	Alu	AluSx1
CAediting_1515701	chrX_85863348_-	SINE	Alu	AluSx1
CAediting_1515702	chrX_85863349_-	SINE	Alu	AluSx1
CAediting_1515703	chrX_85863366_-	SINE	Alu	AluSx1
CAediting_1515704	chrX_85935450_-	DNA	TcMar-Tigger	Tigger3a
CAediting_1515705	chrX_85935478_-	DNA	TcMar-Tigger	Tigger3a
CAediting_1515706	chrX_85935496_-	DNA	TcMar-Tigger	Tigger3a
CAediting_1515707	chrX_85935594_-	DNA	TcMar-Tigger	Tigger3a
CAediting_1515708	chrX_85938978_-	DNA	TcMar-Tigger	Tigger3a
CAediting_1515709	chrX_85938994_-	DNA	TcMar-Tigger	Tigger3a
CAediting_1515710	chrX_85939153_-	DNA	TcMar-Tigger	Tigger3a
CAediting_1515711	chrX_85939173_-	DNA	TcMar-Tigger	Tigger3a
CAediting_1515712	chrX_85939182_-	DNA	TcMar-Tigger	Tigger3a
CAediting_1515713	chrX_85939191_-	DNA	TcMar-Tigger	Tigger3a
CAediting_1515714	chrX_85947504_-	LTR	ERVL-MaLR	MSTA
CAediting_1515715	chrX_85960644_-	SINE	Alu	AluSx
CAediting_1515716	chrX_86017622_-	LTR	ERVL-MaLR	THE1A
CAediting_1515717	chrX_86017670_-	LTR	ERVL-MaLR	THE1A
CAediting_1515718	chrX_86025422_-	SINE	Alu	AluJr4
CAediting_1515719	chrX_86025501_-	SINE	Alu	AluJr4
CAediting_1515720	chrX_86025510_-	SINE	Alu	AluJr4
CAediting_1515721	chrX_86025555_-	SINE	Alu	AluJr4
CAediting_1515722	chrX_86025561_-	SINE	Alu	AluJr4
CAediting_1515723	chrX_86025565_-	SINE	Alu	AluJr4
CAediting_1515724	chrX_86025641_-	SINE	Alu	AluJr4
CAediting_1515725	chrX_86026150_-	SINE	Alu	AluSz
CAediting_1515726	chrX_86026166_-	SINE	Alu	AluSz
CAediting_1515727	chrX_86026169_-	SINE	Alu	AluSz
CAediting_1515728	chrX_86026180_-	SINE	Alu	AluSz
CAediting_1515729	chrX_86026192_-	SINE	Alu	AluSz
CAediting_1515730	chrX_86026193_-	SINE	Alu	AluSz
CAediting_1515731	chrX_86026256_-	SINE	Alu	AluSz
CAediting_1515732	chrX_86026261_-	SINE	Alu	AluSz
CAediting_1515733	chrX_86026262_-	SINE	Alu	AluSz
CAediting_1515734	chrX_86026288_-	SINE	Alu	AluSz
CAediting_1515735	chrX_86026300_-	SINE	Alu	AluSz
CAediting_1515736	chrX_86026303_-	SINE	Alu	AluSz
CAediting_1515737	chrX_86026328_-	SINE	Alu	AluSz
CAediting_1515738	chrX_86026337_-	SINE	Alu	AluSz
CAediting_1515739	chrX_86026359_-	SINE	Alu	AluSz
CAediting_1515740	chrX_86026403_-	SINE	Alu	AluSz
CAediting_1515741	chrX_86026412_-	SINE	Alu	AluSz
CAediting_1515742	chrX_86026426_-	SINE	Alu	AluSz
CAediting_1515743	chrX_86035932_-	SINE	Alu	AluY
CAediting_1515744	chrX_86037316_-	SINE	Alu	AluSq2
CAediting_1515745	chrX_86037336_-	SINE	Alu	AluSq2

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RNA A-to-I editing events in the alternative splicing sites for CHM

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000188419.12.CHM.

Correlation between RNA A-to-I editing and PSI for ENSG00000188419.12.CHM.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CHM

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for CHM

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for CHM

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1515685	chrX_85863186_-	ENSG00000188419.12	ENST00000357749	hsa-miR-671-3p	85863185	85863191	7mer-m8	85863184	85863204	142.00	-18.29
CAediting_1515685	chrX_85863186_-	ENSG00000188419.12	ENST00000357749	hsa-miR-6763-3p	85863182	85863188	7mer-m8	85863181	85863201	140.00	-22.64
CAediting_1515680	chrX_85863120_-	ENSG00000188419.12	ENST00000357749	hsa-miR-1915-5p	85863120	85863125	6mer	85863119	85863140	144.00	-31.94
CAediting_1515680	chrX_85863120_-	ENSG00000188419.12	ENST00000357749	hsa-miR-4312	85863119	85863124	6mer	85863118	85863135	147.00	-27.06
CAediting_1515684	chrX_85863161_-	ENSG00000188419.12	ENST00000357749	hsa-miR-4638-5p	85863158	85863165	8mer-1a	85863158	85863177	146.00	-20.28
CAediting_1515686	chrX_85863189_-	ENSG00000188419.12	ENST00000357749	hsa-miR-149-5p	85863185	85863191	7mer-m8	85863184	85863210	149.00	-21.12
CAediting_1515687	chrX_85863190_-	ENSG00000188419.12	ENST00000357749	hsa-miR-3663-5p	85863185	85863190	6mer	85863184	85863204	142.00	-19.93
CAediting_1515687	chrX_85863190_-	ENSG00000188419.12	ENST00000357749	hsa-miR-7152-3p	85863185	85863191	7mer-m8	85863184	85863203	147.00	-19.59
CAediting_1515688	chrX_85863245_-	ENSG00000188419.12	ENST00000357749	hsa-miR-5003-5p	85863243	85863249	7mer-m8	85863242	85863264	153.00	-18.94
CAediting_1515690	chrX_85863262_-	ENSG00000188419.12	ENST00000357749	hsa-miR-643	85863261	85863268	8mer-1a	85863261	85863283	143.00	-14.77
CAediting_1515692	chrX_85863266_-	ENSG00000188419.12	ENST00000357749	hsa-miR-153-5p	85863266	85863272	7mer-m8	85863265	85863285	146.00	-9.95
CAediting_1515692	chrX_85863266_-	ENSG00000188419.12	ENST00000357749	hsa-miR-3680-3p	85863261	85863268	8mer-1a	85863261	85863283	140.00	-13.99
CAediting_1515692	chrX_85863266_-	ENSG00000188419.12	ENST00000357749	hsa-miR-3680-3p	85863261	85863268	8mer-1a	85863261	85863283	140.00	-13.99
CAediting_1515695	chrX_85863275_-	ENSG00000188419.12	ENST00000357749	hsa-miR-2467-3p	85863274	85863279	6mer	85863273	85863294	141.00	-22.08
CAediting_1515695	chrX_85863275_-	ENSG00000188419.12	ENST00000357749	hsa-miR-374b-3p	85863270	85863277	8mer-1a	85863270	85863291	141.00	-8.66
CAediting_1515696	chrX_85863286_-	ENSG00000188419.12	ENST00000357749	hsa-miR-3158-3p	85863282	85863288	7mer-m8	85863281	85863301	150.00	-19.46
CAediting_1515696	chrX_85863286_-	ENSG00000188419.12	ENST00000357749	hsa-miR-3158-3p	85863282	85863288	7mer-m8	85863281	85863301	150.00	-19.46
CAediting_1515697	chrX_85863296_-	ENSG00000188419.12	ENST00000357749	hsa-miR-3190-5p	85863296	85863302	7mer-m8	85863295	85863314	154.00	-19.64
CAediting_1515700	chrX_85863335_-	ENSG00000188419.12	ENST00000357749	hsa-miR-640	85863330	85863336	7mer-m8	85863329	85863349	151.00	-20.25
CAediting_1515702	chrX_85863349_-	ENSG00000188419.12	ENST00000357749	hsa-miR-6736-3p	85863343	85863350	8mer-1a	85863343	85863363	146.00	-18.17
CAediting_1515702	chrX_85863349_-	ENSG00000188419.12	ENST00000357749	hsa-miR-7106-3p	85863346	85863351	6mer	85863345	85863367	141.00	-18.53
CAediting_1515703	chrX_85863366_-	ENSG00000188419.12	ENST00000357749	hsa-miR-513a-5p	85863365	85863371	7mer-m8	85863364	85863381	147.00	-15.60
CAediting_1515703	chrX_85863366_-	ENSG00000188419.12	ENST00000357749	hsa-miR-513a-5p	85863365	85863371	7mer-m8	85863364	85863381	147.00	-15.60
CAediting_1515703	chrX_85863366_-	ENSG00000188419.12	ENST00000357749	hsa-miR-638	85863360	85863366	7mer-1a	85863360	85863386	152.00	-33.59
CAediting_1515681	chrX_85863122_-	ENSG00000188419.12	ENST00000357749	hsa-miR-6838-3p	85863118	85863124	7mer-m8	85863117	85863135	168.00	-24.31
CAediting_1515683	chrX_85863160_-	ENSG00000188419.12	ENST00000357749	hsa-miR-149-5p	85863160	85863166	7mer-m8	85863159	85863181	148.00	-24.00
CAediting_1515699	chrX_85863317_-	ENSG00000188419.12	ENST00000357749	hsa-miR-4732-3p	85863317	85863323	7mer-m8	85863316	85863336	155.00	-22.25
CAediting_1515701	chrX_85863348_-	ENSG00000188419.12	ENST00000357749	hsa-miR-150-5p	85863348	85863354	7mer-m8	85863347	85863368	140.00	-15.80
CAediting_1515701	chrX_85863348_-	ENSG00000188419.12	ENST00000357749	hsa-miR-6778-3p	85863346	85863352	7mer-m8	85863345	85863365	143.00	-14.47

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1515703	chrX_85863366_-	ENSG00000188419.12	ENST00000357749	hsa-miR-10399-5p	85863364	85863370	7mer-m8	85863363	85863383	150	-11.87
CAediting_1515698	chrX_85863306_-	ENSG00000188419.12	ENST00000357749	hsa-miR-3663-5p	85863305	85863311	7mer-m8	85863304	85863323	148	-21.98
CAediting_1515690	chrX_85863262_-	ENSG00000188419.12	ENST00000357749	hsa-miR-4282	85863256	85863263	8mer-1a	85863256	85863274	143	-3.81
CAediting_1515680	chrX_85863120_-	ENSG00000188419.12	ENST00000357749	hsa-miR-431-5p	85863119	85863125	7mer-m8	85863118	85863136	147	-17.87
CAediting_1515681	chrX_85863122_-	ENSG00000188419.12	ENST00000357749	hsa-miR-431-5p	85863119	85863125	7mer-m8	85863118	85863136	147	-17.87
CAediting_1515682	chrX_85863123_-	ENSG00000188419.12	ENST00000357749	hsa-miR-431-5p	85863119	85863125	7mer-m8	85863118	85863136	147	-17.87
CAediting_1515699	chrX_85863317_-	ENSG00000188419.12	ENST00000357749	hsa-miR-4680-5p	85863313	85863318	6mer	85863312	85863332	142	-19.36
CAediting_1515697	chrX_85863296_-	ENSG00000188419.12	ENST00000357749	hsa-miR-4716-5p	85863291	85863297	7mer-m8	85863290	85863311	140	-10.69
CAediting_1515697	chrX_85863296_-	ENSG00000188419.12	ENST00000357749	hsa-miR-4781-3p	85863293	85863299	7mer-m8	85863292	85863310	144	-13.86
CAediting_1515680	chrX_85863120_-	ENSG00000188419.12	ENST00000357749	hsa-miR-5007-5p	85863116	85863122	7mer-m8	85863115	85863136	152	-17.12
CAediting_1515700	chrX_85863335_-	ENSG00000188419.12	ENST00000357749	hsa-miR-5591-3p	85863335	85863340	6mer	85863334	85863352	144	-24.23
CAediting_1515682	chrX_85863123_-	ENSG00000188419.12	ENST00000357749	hsa-miR-5691	85863122	85863129	8mer-1a	85863122	85863142	147	-19.02
CAediting_1515698	chrX_85863306_-	ENSG00000188419.12	ENST00000357749	hsa-miR-6131	85863304	85863310	7mer-m8	85863303	85863321	140	-18.33
CAediting_1515703	chrX_85863366_-	ENSG00000188419.12	ENST00000357749	hsa-miR-6504-3p	85863364	85863370	7mer-m8	85863363	85863381	155	-16.28
CAediting_1515682	chrX_85863123_-	ENSG00000188419.12	ENST00000357749	hsa-miR-6805-3p	85863122	85863129	8mer-1a	85863122	85863144	154	-21.46
CAediting_1515696	chrX_85863286_-	ENSG00000188419.12	ENST00000357749	hsa-miR-6823-5p	85863281	85863287	7mer-m8	85863280	85863300	143	-17.8
CAediting_1515695	chrX_85863275_-	ENSG00000188419.12	ENST00000357749	hsa-miR-6832-5p	85863274	85863280	7mer-m8	85863273	85863295	140	-18.87
CAediting_1515698	chrX_85863306_-	ENSG00000188419.12	ENST00000357749	hsa-miR-6843-3p	85863306	85863312	7mer-m8	85863305	85863324	152	-19.47
CAediting_1515698	chrX_85863306_-	ENSG00000188419.12	ENST00000357749	hsa-miR-6848-3p	85863306	85863312	7mer-m8	85863305	85863322	142	-14.3
CAediting_1515685	chrX_85863186_-	ENSG00000188419.12	ENST00000357749	hsa-miR-7113-3p	85863181	85863187	7mer-m8	85863180	85863202	140	-20.22
CAediting_1515703	chrX_85863366_-	ENSG00000188419.12	ENST00000357749	hsa-miR-7151-3p	85863365	85863372	8mer-1a	85863365	85863385	142	-13.72

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_980496	chr14_31014685_-	ENSG00000188419.12	ENST00000357749	hsa-miR-624-3p	85863280	85863286	7mer-m8	85863279	85863299	156	-16.49
CAediting_980496	chr14_31014685_-	ENSG00000188419.12	ENST00000357749	hsa-miR-624-3p	85862178	85862184	7mer-m8	85862177	85862196	151	-15.38
CAediting_846604	chr11_93733708_-	ENSG00000188419.12	ENST00000615443	hsa-miR-1304-3p	85971415	85971422	8mer-1a	85971415	85971436	140	-18.13
CAediting_1229414	chr17_67471546_+	ENSG00000188419.12	ENST00000357749	hsa-miR-548aa	85864312	85864319	8mer-1a	85864312	85864336	154	-9.81
CAediting_1368054	chr19_46709310_-	ENSG00000188419.12	ENST00000357749	hsa-miR-320e	85864251	85864258	8mer-1a	85864251	85864269	159	-19.04
CAediting_1399425	chr20_1392958_-	ENSG00000188419.12	ENST00000357749	hsa-miR-6869-5p	85862733	85862739	7mer-m8	85862732	85862753	156	-23.73
CAediting_1160181	chr17_7017644_-	ENSG00000188419.12	ENST00000615443	hsa-miR-195-3p	85970163	85970169	7mer-m8	85970162	85970184	149	-12.21
CAediting_1351755	chr19_40282625_-	ENSG00000188419.12	ENST00000615443	hsa-miR-641	85969645	85969651	7mer-m8	85969644	85969667	140	-16.46
CAediting_117844	chr1_162342605_+	ENSG00000188419.12	ENST00000615443	hsa-miR-556-3p	85971140	85971146	7mer-m8	85971139	85971160	140	-10.61
CAediting_573001	chr7_92204086_-	ENSG00000188419.12	ENST00000615443	hsa-miR-1285-5p	85971282	85971288	7mer-m8	85971281	85971301	147	-16.36

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_393	chr1_1167164_+	ENSG00000188419.12	ENST00000357749	hsa-miR-200b-3p	85861481	85861488	8mer-1a	85861481	85861501	151	-14.44
CAediting_117844	chr1_162342605_+	ENSG00000188419.12	ENST00000357749	hsa-miR-556-3p	85864506	85864512	7mer-m8	85864505	85864527	147	-8.23
CAediting_573001	chr7_92204086_-	ENSG00000188419.12	ENST00000615443	hsa-miR-1285-5p	85969880	85969886	7mer-m8	85969879	85969901	149	-17.27
CAediting_846604	chr11_93733708_-	ENSG00000188419.12	ENST00000615443	hsa-miR-1304-3p	85971283	85971290	8mer-1a	85971283	85971301	141	-14.02
CAediting_393	chr1_1167164_+	ENSG00000188419.12	ENST00000615443	hsa-miR-200b-3p	85970348	85970353	6mer	85970347	85970368	141	-11.62
CAediting_393	chr1_1167164_+	ENSG00000188419.12	ENST00000615443	hsa-miR-200b-3p	85969869	85969875	7mer-m8	85969868	85969889	150	-10.94

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for CHM

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for CHM

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

Top

Relation with cancer stages for CHM

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

Top

Relation with survival for CHM

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

Top

RelatedDrugs for CHM

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for CHM

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
CHM	C0008525	Choroideremia	3	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene