CAeditome Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: CPSF6 (CAeditome ID:11052)

Gene summary for CPSF6

check button Gene summary
Gene informationGene symbol

CPSF6

Gene ID

11052

Gene namecleavage and polyadenylation specific factor 6
SynonymsCFIM|CFIM68|CFIM72|HPBRII-4|HPBRII-7
Cytomap

12q15

Type of geneprotein-coding
Descriptioncleavage and polyadenylation specificity factor subunit 6CPSF 68 kDa subunitcleavage and polyadenylation specific factor 6, 68kDacleavage and polyadenylation specificity factor 68 kDa subunitcleavage factor Im complex 68 kDa subunitpre-mRNA cleavage
Modification date20210518
UniProtAcc

Q16630

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
CPSF6

GO:0003723

Cleavage and polyadenylation specificity factor subunit 6

15169763

CPSF6

GO:0003729

Cleavage and polyadenylation specificity factor subunit 6

21295486

CPSF6

GO:0043023

Cleavage and polyadenylation specificity factor subunit 6

19864460

CPSF6

GO:1990448

Cleavage and polyadenylation specificity factor subunit 6

19864460

CPSF6

GO:0006397

Cleavage and polyadenylation specificity factor subunit 6

14690600

CPSF6

GO:0051262

Cleavage and polyadenylation specificity factor subunit 6

20695905

CPSF6

GO:0051290

Cleavage and polyadenylation specificity factor subunit 6

23187700

CPSF6

GO:1990120

Cleavage and polyadenylation specificity factor subunit 6

29276085

CPSF6

GO:0005634

Cleavage and polyadenylation specificity factor subunit 6

19864460

CPSF6

GO:0005634

Cleavage and polyadenylation specificity factor subunit 6

20695905

CPSF6

GO:0005634

Cleavage and polyadenylation specificity factor subunit 6

30916345

CPSF6

GO:0005654

Cleavage and polyadenylation specificity factor subunit 6

0000052

CPSF6

GO:0005654

Cleavage and polyadenylation specificity factor subunit 6

17267687

CPSF6

GO:0005726

Cleavage and polyadenylation specificity factor subunit 6

17267687

CPSF6

GO:0005737

Cleavage and polyadenylation specificity factor subunit 6

19864460

CPSF6

GO:0005737

Cleavage and polyadenylation specificity factor subunit 6

30916345

CPSF6

GO:0016607

Cleavage and polyadenylation specificity factor subunit 6

0000052

CPSF6

GO:0016607

Cleavage and polyadenylation specificity factor subunit 6

17267687

CPSF6

GO:0035061

Cleavage and polyadenylation specificity factor subunit 6

17267687

CPSF6

GO:0042382

Cleavage and polyadenylation specificity factor subunit 6

17267687

CPSF6

GO:0042382

Cleavage and polyadenylation specificity factor subunit 6

9659921

CPSF6

GO:0005847

Cleavage and polyadenylation specificity factor subunit 6

23187700

CPSF6

GO:0005849

Cleavage and polyadenylation specificity factor subunit 6

20695905

CPSF6

GO:0005849

Cleavage and polyadenylation specificity factor subunit 6

29276085

CPSF6

GO:0005849

Cleavage and polyadenylation specificity factor subunit 6

9659921

CPSF6

GO:1990904

Cleavage and polyadenylation specificity factor subunit 6

18809582


Top

RNA A-to-I events for CPSF6

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000111605.15

check button RNA A-to-I editing events in Cancer.
CAediting_908550(69242956, +), CAediting_908551(69242966, +), CAediting_908552(69242987, +), CAediting_908553(69242988, +), CAediting_908554(69242993, +), CAediting_908555(69243028, +), CAediting_908556(69243035, +), CAediting_908557(69243920, +), CAediting_908558(69243927, +), CAediting_908559(69243933, +), CAediting_908560(69243934, +), CAediting_908561(69243937, +), CAediting_908562(69243958, +), CAediting_908563(69243986, +), CAediting_908564(69244036, +), CAediting_908565(69244094, +), CAediting_908566(69244286, +), CAediting_908567(69244291, +), CAediting_908568(69244335, +), CAediting_908569(69244336, +), CAediting_908570(69244389, +), CAediting_908571(69244390, +), CAediting_908572(69244398, +), CAediting_908573(69244404, +), CAediting_908574(69244486, +), CAediting_908575(69244504, +), CAediting_908576(69244588, +), CAediting_908577(69244595, +), CAediting_908578(69244633, +), CAediting_908579(69244997, +), CAediting_908580(69245048, +), CAediting_908581(69245803, +), CAediting_908582(69245808, +), CAediting_908583(69245831, +), CAediting_908584(69245854, +), CAediting_908585(69245866, +), CAediting_908586(69245900, +), CAediting_908587(69245910, +), CAediting_908588(69245922, +), CAediting_908589(69245926, +), CAediting_908590(69245928, +), CAediting_908591(69245940, +), CAediting_908592(69245944, +), CAediting_908593(69245966, +), CAediting_908594(69245967, +), CAediting_908595(69245976, +), CAediting_908596(69245981, +), CAediting_908597(69246007, +), CAediting_908598(69246008, +), CAediting_908599(69246028, +), CAediting_908600(69246042, +), CAediting_908601(69246849, +), CAediting_908602(69246873, +), CAediting_908603(69246948, +), CAediting_908604(69249030, +), CAediting_908605(69249122, +), CAediting_908606(69250454, +), CAediting_908607(69250492, +), CAediting_908608(69250544, +), CAediting_908609(69250567, +), CAediting_908610(69250666, +), CAediting_908611(69250671, +), CAediting_908612(69250708, +), CAediting_908613(69250724, +), CAediting_908614(69250740, +), CAediting_908615(69250747, +), CAediting_908616(69250777, +), CAediting_908617(69250821, +), CAediting_908618(69250836, +), CAediting_908619(69250856, +), CAediting_908620(69250882, +), CAediting_908621(69255003, +), CAediting_908622(69255041, +), CAediting_908623(69255115, +), CAediting_908624(69255120, +), CAediting_908625(69255124, +), CAediting_908626(69255125, +), CAediting_908627(69255136, +), CAediting_908628(69255137, +), CAediting_908629(69255145, +), CAediting_908630(69255172, +), CAediting_908631(69255186, +), CAediting_908632(69255187, +), CAediting_908633(69255214, +), CAediting_908634(69255227, +), CAediting_908635(69255297, +), CAediting_908636(69255964, +), CAediting_908637(69255971, +), CAediting_908638(69255980, +), CAediting_908639(69256050, +), CAediting_908640(69256051, +), CAediting_908641(69256052, +), CAediting_908642(69256056, +), CAediting_908643(69256086, +), CAediting_908644(69256102, +), CAediting_908645(69256108, +), CAediting_908646(69256123, +), CAediting_908647(69256151, +), CAediting_908648(69256157, +), CAediting_908649(69256158, +), CAediting_908650(69256226, +), CAediting_908651(69256341, +), CAediting_908652(69257815, +), CAediting_908653(69260851, +), CAediting_908654(69261318, +), CAediting_908655(69261320, +), CAediting_908656(69261338, +), CAediting_908657(69261347, +), CAediting_908658(69265672, +), CAediting_908659(69265748, +),

Top

RNA editing positional annotations for CPSF6 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_908550chr12_69242956_+ncRNA_intronic
CAediting_908551chr12_69242966_+ncRNA_intronic
CAediting_908552chr12_69242987_+ncRNA_intronic
CAediting_908553chr12_69242988_+ncRNA_intronic
CAediting_908554chr12_69242993_+ncRNA_intronic
CAediting_908555chr12_69243028_+ncRNA_intronic
CAediting_908556chr12_69243035_+ncRNA_intronic
CAediting_908557chr12_69243920_+ncRNA_intronic
CAediting_908558chr12_69243927_+ncRNA_intronic
CAediting_908559chr12_69243933_+ncRNA_intronic
CAediting_908560chr12_69243934_+ncRNA_intronic
CAediting_908561chr12_69243937_+ncRNA_intronic
CAediting_908562chr12_69243958_+ncRNA_intronic
CAediting_908563chr12_69243986_+ncRNA_intronic
CAediting_908564chr12_69244036_+ncRNA_intronic
CAediting_908565chr12_69244094_+ncRNA_intronic
CAediting_908566chr12_69244286_+ncRNA_intronic
CAediting_908567chr12_69244291_+ncRNA_intronic
CAediting_908568chr12_69244335_+ncRNA_intronic
CAediting_908569chr12_69244336_+ncRNA_intronic
CAediting_908570chr12_69244389_+ncRNA_intronic
CAediting_908571chr12_69244390_+ncRNA_intronic
CAediting_908572chr12_69244398_+ncRNA_intronic
CAediting_908573chr12_69244404_+ncRNA_intronic
CAediting_908574chr12_69244486_+ncRNA_intronic
CAediting_908575chr12_69244504_+ncRNA_intronic
CAediting_908576chr12_69244588_+ncRNA_intronic
CAediting_908577chr12_69244595_+ncRNA_intronic
CAediting_908578chr12_69244633_+ncRNA_intronic
CAediting_908579chr12_69244997_+ncRNA_intronic
CAediting_908580chr12_69245048_+ncRNA_intronic
CAediting_908581chr12_69245803_+ncRNA_intronic
CAediting_908582chr12_69245808_+ncRNA_intronic
CAediting_908583chr12_69245831_+ncRNA_intronic
CAediting_908584chr12_69245854_+ncRNA_intronic
CAediting_908585chr12_69245866_+ncRNA_intronic
CAediting_908586chr12_69245900_+ncRNA_intronic
CAediting_908587chr12_69245910_+ncRNA_intronic
CAediting_908588chr12_69245922_+ncRNA_intronic
CAediting_908589chr12_69245926_+ncRNA_intronic
CAediting_908590chr12_69245928_+ncRNA_intronic
CAediting_908591chr12_69245940_+ncRNA_intronic
CAediting_908592chr12_69245944_+ncRNA_intronic
CAediting_908593chr12_69245966_+ncRNA_intronic
CAediting_908594chr12_69245967_+ncRNA_intronic
CAediting_908595chr12_69245976_+ncRNA_intronic
CAediting_908596chr12_69245981_+ncRNA_intronic
CAediting_908597chr12_69246007_+ncRNA_intronic
CAediting_908598chr12_69246008_+ncRNA_intronic
CAediting_908599chr12_69246028_+ncRNA_intronic
CAediting_908600chr12_69246042_+ncRNA_intronic
CAediting_908601chr12_69246849_+ncRNA_intronic
CAediting_908602chr12_69246873_+ncRNA_intronic
CAediting_908603chr12_69246948_+ncRNA_intronic
CAediting_908604chr12_69249030_+ncRNA_intronic
CAediting_908605chr12_69249122_+ncRNA_intronic
CAediting_908606chr12_69250454_+ncRNA_intronic
CAediting_908607chr12_69250492_+ncRNA_intronic
CAediting_908608chr12_69250544_+ncRNA_intronic
CAediting_908609chr12_69250567_+ncRNA_intronic
CAediting_908610chr12_69250666_+ncRNA_intronic
CAediting_908611chr12_69250671_+ncRNA_intronic
CAediting_908612chr12_69250708_+ncRNA_intronic
CAediting_908613chr12_69250724_+ncRNA_intronic
CAediting_908614chr12_69250740_+ncRNA_intronic
CAediting_908615chr12_69250747_+ncRNA_intronic
CAediting_908616chr12_69250777_+ncRNA_intronic
CAediting_908617chr12_69250821_+ncRNA_intronic
CAediting_908618chr12_69250836_+ncRNA_intronic
CAediting_908619chr12_69250856_+ncRNA_intronic
CAediting_908620chr12_69250882_+ncRNA_intronic
CAediting_908621chr12_69255003_+ncRNA_exonic
CAediting_908622chr12_69255041_+ncRNA_exonic
CAediting_908623chr12_69255115_+ncRNA_exonic
CAediting_908624chr12_69255120_+ncRNA_exonic
CAediting_908625chr12_69255124_+ncRNA_exonic
CAediting_908626chr12_69255125_+ncRNA_exonic
CAediting_908627chr12_69255136_+ncRNA_exonic
CAediting_908628chr12_69255137_+ncRNA_exonic
CAediting_908629chr12_69255145_+ncRNA_exonic
CAediting_908630chr12_69255172_+ncRNA_intronic
CAediting_908631chr12_69255186_+ncRNA_intronic
CAediting_908632chr12_69255187_+ncRNA_intronic
CAediting_908633chr12_69255214_+ncRNA_intronic
CAediting_908634chr12_69255227_+ncRNA_intronic
CAediting_908635chr12_69255297_+ncRNA_intronic
CAediting_908636chr12_69255964_+ncRNA_intronic
CAediting_908637chr12_69255971_+ncRNA_intronic
CAediting_908638chr12_69255980_+ncRNA_intronic
CAediting_908639chr12_69256050_+ncRNA_intronic
CAediting_908640chr12_69256051_+ncRNA_intronic
CAediting_908641chr12_69256052_+ncRNA_intronic
CAediting_908642chr12_69256056_+ncRNA_intronic
CAediting_908643chr12_69256086_+ncRNA_intronic
CAediting_908644chr12_69256102_+ncRNA_intronic
CAediting_908645chr12_69256108_+ncRNA_intronic
CAediting_908646chr12_69256123_+ncRNA_intronic
CAediting_908647chr12_69256151_+ncRNA_intronic
CAediting_908648chr12_69256157_+ncRNA_intronic
CAediting_908649chr12_69256158_+ncRNA_intronic
CAediting_908650chr12_69256226_+ncRNA_intronic
CAediting_908651chr12_69256341_+ncRNA_intronic
CAediting_908652chr12_69257815_+exonic
CAediting_908653chr12_69260851_+intronic
CAediting_908654chr12_69261318_+intronic
CAediting_908655chr12_69261320_+intronic
CAediting_908656chr12_69261338_+intronic
CAediting_908657chr12_69261347_+intronic
CAediting_908658chr12_69265672_+intronic
CAediting_908659chr12_69265748_+intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_908550chr12_69242956_+SINEAluAluSz
CAediting_908551chr12_69242966_+SINEAluAluSz
CAediting_908552chr12_69242987_+SINEAluAluSz
CAediting_908553chr12_69242988_+SINEAluAluSz
CAediting_908554chr12_69242993_+SINEAluAluSz
CAediting_908555chr12_69243028_+SINEAluAluSz
CAediting_908556chr12_69243035_+SINEAluAluSz
CAediting_908557chr12_69243920_+SINEAluAluJb
CAediting_908558chr12_69243927_+SINEAluAluJb
CAediting_908559chr12_69243933_+SINEAluAluJb
CAediting_908560chr12_69243934_+SINEAluAluJb
CAediting_908561chr12_69243937_+SINEAluAluJb
CAediting_908562chr12_69243958_+SINEAluAluJb
CAediting_908563chr12_69243986_+SINEAluAluJb
CAediting_908564chr12_69244036_+SINEAluAluJb
CAediting_908565chr12_69244094_+SINEAluAluJb
CAediting_908566chr12_69244286_+SINEAluAluSz
CAediting_908567chr12_69244291_+SINEAluAluSz
CAediting_908568chr12_69244335_+SINEAluAluSz
CAediting_908569chr12_69244336_+SINEAluAluSz
CAediting_908570chr12_69244389_+SINEAluAluSz
CAediting_908571chr12_69244390_+SINEAluAluSz
CAediting_908572chr12_69244398_+SINEAluAluSz
CAediting_908573chr12_69244404_+SINEAluAluSz
CAediting_908574chr12_69244486_+SINEAluAluSz
CAediting_908575chr12_69244504_+SINEAluAluSz
CAediting_908576chr12_69244588_+SINEAluFLAM_C
CAediting_908577chr12_69244595_+SINEAluFLAM_C
CAediting_908578chr12_69244633_+SINEAluFLAM_C
CAediting_908579chr12_69244997_+SINEAluAluSz6
CAediting_908580chr12_69245048_+SINEAluAluSz6
CAediting_908582chr12_69245808_+SINEAluAluSz
CAediting_908583chr12_69245831_+SINEAluAluSz
CAediting_908584chr12_69245854_+SINEAluAluSz
CAediting_908585chr12_69245866_+SINEAluAluSz
CAediting_908586chr12_69245900_+SINEAluAluSz
CAediting_908587chr12_69245910_+SINEAluAluSz
CAediting_908588chr12_69245922_+SINEAluAluSz
CAediting_908589chr12_69245926_+SINEAluAluSz
CAediting_908590chr12_69245928_+SINEAluAluSz
CAediting_908591chr12_69245940_+SINEAluAluSz
CAediting_908592chr12_69245944_+SINEAluAluSz
CAediting_908593chr12_69245966_+SINEAluAluSz
CAediting_908594chr12_69245967_+SINEAluAluSz
CAediting_908595chr12_69245976_+SINEAluAluSz
CAediting_908596chr12_69245981_+SINEAluAluSz
CAediting_908597chr12_69246007_+SINEAluAluSz
CAediting_908598chr12_69246008_+SINEAluAluSz
CAediting_908599chr12_69246028_+SINEAluAluSz
CAediting_908600chr12_69246042_+SINEAluAluSz
CAediting_908601chr12_69246849_+SINEAluAluJo
CAediting_908602chr12_69246873_+SINEAluAluJo
CAediting_908603chr12_69246948_+SINEAluAluJo
CAediting_908604chr12_69249030_+SINEAluAluYf1
CAediting_908605chr12_69249122_+SINEAluAluYf1
CAediting_908607chr12_69250492_+SINEAluFLAM_C
CAediting_908608chr12_69250544_+SINEAluFLAM_C
CAediting_908609chr12_69250567_+SINEAluFLAM_C
CAediting_908610chr12_69250666_+SINEAluAluSz
CAediting_908611chr12_69250671_+SINEAluAluSz
CAediting_908612chr12_69250708_+SINEAluAluSz
CAediting_908613chr12_69250724_+SINEAluAluSz
CAediting_908614chr12_69250740_+SINEAluAluSz
CAediting_908615chr12_69250747_+SINEAluAluSz
CAediting_908616chr12_69250777_+SINEAluAluSz
CAediting_908617chr12_69250821_+SINEAluAluSz
CAediting_908618chr12_69250836_+SINEAluAluSz
CAediting_908619chr12_69250856_+SINEAluAluSz
CAediting_908620chr12_69250882_+SINEAluAluSz
CAediting_908621chr12_69255003_+LINEL1L1MB7
CAediting_908622chr12_69255041_+LINEL1L1MB7
CAediting_908623chr12_69255115_+LINEL1L1MB7
CAediting_908624chr12_69255120_+LINEL1L1MB7
CAediting_908625chr12_69255124_+LINEL1L1MB7
CAediting_908626chr12_69255125_+LINEL1L1MB7
CAediting_908627chr12_69255136_+LINEL1L1MB7
CAediting_908628chr12_69255137_+LINEL1L1MB7
CAediting_908629chr12_69255145_+LINEL1L1MB7
CAediting_908630chr12_69255172_+LINEL1L1MB7
CAediting_908631chr12_69255186_+LINEL1L1MB7
CAediting_908632chr12_69255187_+LINEL1L1MB7
CAediting_908633chr12_69255214_+LINEL1L1MB7
CAediting_908634chr12_69255227_+LINEL1L1MB7
CAediting_908635chr12_69255297_+LINEL1L1MB7
CAediting_908636chr12_69255964_+LINEL1L1MB8
CAediting_908637chr12_69255971_+LINEL1L1MB8
CAediting_908638chr12_69255980_+LINEL1L1MB8
CAediting_908639chr12_69256050_+LINEL1L1MB8
CAediting_908640chr12_69256051_+LINEL1L1MB8
CAediting_908641chr12_69256052_+LINEL1L1MB8
CAediting_908642chr12_69256056_+LINEL1L1MB8
CAediting_908643chr12_69256086_+LINEL1L1MB8
CAediting_908644chr12_69256102_+LINEL1L1MB8
CAediting_908645chr12_69256108_+LINEL1L1MB8
CAediting_908646chr12_69256123_+LINEL1L1MB8
CAediting_908647chr12_69256151_+LINEL1L1MB8
CAediting_908648chr12_69256157_+LINEL1L1MB8
CAediting_908649chr12_69256158_+LINEL1L1MB8
CAediting_908650chr12_69256226_+LINEL1L1MB8
CAediting_908651chr12_69256341_+LINEL1L1MB8
CAediting_908653chr12_69260851_+SINEAluFLAM_C
CAediting_908654chr12_69261318_+SINEAluAluJb
CAediting_908655chr12_69261320_+SINEAluAluJb
CAediting_908656chr12_69261338_+SINEAluAluJb
CAediting_908657chr12_69261347_+SINEAluAluJb
CAediting_908658chr12_69265672_+SINEAluAluSp
CAediting_908659chr12_69265748_+SINEAluAluSp

Top

RNA A-to-I editing events in the alternative splicing sites for CPSF6

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESCAediting_908621chr12_69255003_+69254981:692550033SS3+0iATTACCACTGTCTCATTCCAGAA-8.09ATTACCACTGTCTCATTCCAGAG-8.98
MEX_1CAediting_908621chr12_69255003_+69254981:692550033SS3+0iATTACCACTGTCTCATTCCAGAA-8.09ATTACCACTGTCTCATTCCAGAG-8.98
ESCAediting_908622chr12_69255041_+69255035:692550435SS0+4iCTGGTTAGC2.22CTGGTTGGC1.14
MEX_1CAediting_908622chr12_69255041_+69255035:692550435SS0+4iCTGGTTAGC2.22CTGGTTGGC1.14
ESCAediting_908639chr12_69256050_+69256050:692560585SS3+0iAAAGTAAGT9.72GAAGTAAGT9.82
MEX_2CAediting_908639chr12_69256050_+69256050:692560585SS3+0iAAAGTAAGT9.72GAAGTAAGT9.82
ESCAediting_908640chr12_69256051_+69256050:692560585SS2+0iAAAGTAAGT9.72AGAGTAAGT9.35
MEX_2CAediting_908640chr12_69256051_+69256050:692560585SS2+0iAAAGTAAGT9.72AGAGTAAGT9.35
ESCAediting_908641chr12_69256052_+69256050:692560585SS1+0iAAAGTAAGT9.72AAGGTAAGT11
MEX_2CAediting_908641chr12_69256052_+69256050:692560585SS1+0iAAAGTAAGT9.72AAGGTAAGT11
ESCAediting_908642chr12_69256056_+69256050:692560585SS0+4iAAAGTAAGT9.72AAAGTAGGT6.84
MEX_2CAediting_908642chr12_69256056_+69256050:692560585SS0+4iAAAGTAAGT9.72AAAGTAGGT6.84

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000111605.15.CPSF6.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000111605.15.CPSF6.
boxplot

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for CPSF6

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Top

Protein coding region RNA A-to-I editings for CPSF6

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.
all structure


Top

The effects of the RNA editing to the miRNA binding sites for CPSF6

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1229415chr17_67471547_+ENSG00000111605.15ENST00000435070hsa-miR-548aa69271308692713147mer-m86927128969271315146-10.01
CAediting_1229415chr17_67471547_+ENSG00000111605.15ENST00000435070hsa-miR-548aa69272200692722067mer-m86927218269272207161-18.48
CAediting_1160181chr17_7017644_-ENSG00000111605.15ENST00000435070hsa-miR-195-3p69273792692737998mer-1a6927377669273799151-16.18
CAediting_1160181chr17_7017644_-ENSG00000111605.15ENST00000435070hsa-miR-195-3p69270406692704138mer-1a6927039269270413160-13.69
CAediting_228905chr2_188297554_+ENSG00000111605.15ENST00000435070hsa-miR-561-3p69271825692718317mer-m86927180869271832150-7.17
CAediting_228905chr2_188297554_+ENSG00000111605.15ENST00000435070hsa-miR-561-3p69273520692735267mer-m86927350569273527156-15.81

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1160181chr17_7017644_-ENSG00000111605.15ENST00000435070hsa-miR-195-3p69272332692723387mer-m86927231869272339143-10.32
CAediting_393chr1_1167164_+ENSG00000111605.15ENST00000435070hsa-miR-200b-3p69270608692706147mer-m86927059769270615146-10.24
CAediting_393chr1_1167164_+ENSG00000111605.15ENST00000435070hsa-miR-200b-3p69272665692726717mer-m86927264769272672142-12.88
CAediting_1229415chr17_67471547_+ENSG00000111605.15ENST00000435070hsa-miR-548aa69272699692727057mer-m86927268169272706145-9.76
CAediting_1229413chr17_67471544_+ENSG00000111605.15ENST00000435070hsa-miR-548aa69272699692727057mer-m86927268169272706145-9.76
CAediting_1229414chr17_67471546_+ENSG00000111605.15ENST00000435070hsa-miR-548aa69272699692727057mer-m86927268169272706145-9.76
CAediting_1229415chr17_67471547_+ENSG00000111605.15ENST00000435070hsa-miR-548aa69273323692733297mer-m86927330569273330150-10.96
CAediting_1229413chr17_67471544_+ENSG00000111605.15ENST00000435070hsa-miR-548aa69273323692733297mer-m86927330569273330150-10.96
CAediting_1229414chr17_67471546_+ENSG00000111605.15ENST00000435070hsa-miR-548aa69273323692733297mer-m86927330569273330150-10.96
CAediting_228905chr2_188297554_+ENSG00000111605.15ENST00000435070hsa-miR-561-3p69274343692743497mer-m86927432969274350140-3.31
CAediting_1351755chr19_40282625_-ENSG00000111605.15ENST00000435070hsa-miR-64169273373692733797mer-m86927335669273380148-13.56

check button Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for CPSF6

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

Top

Relation with ADAR for CPSF6

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

Top

Relation with cancer stages for CPSF6

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

Top

Relation with survival for CPSF6

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

Top

RelatedDrugs for CPSF6

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for CPSF6

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource