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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: DSTN (CAeditome ID:11034)

Gene summary for DSTN

check button Gene summary
Gene informationGene symbol

DSTN

Gene ID

11034

Gene namedestrin, actin depolymerizing factor
SynonymsACTDP|ADF|HEL32|bA462D18.2
Cytomap

20p12.1

Type of geneprotein-coding
Descriptiondestrinactin-depolymerizing factorbA462D18.2 (destrin (actin depolymerizing factor ADF) (ACTDP))epididymis luminal protein 32epididymis secretory sperm binding protein
Modification date20210518
UniProtAcc

P60981

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
DSTN

GO:0051015

Destrin

11812157

DSTN

GO:0051015

Destrin

8399167

DSTN

GO:0030042

Destrin

11812157


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RNA A-to-I events for DSTN

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000125868.14
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_1407686(17573938, +), CAediting_1407687(17573950, +), CAediting_1407688(17573961, +), CAediting_1407689(17573971, +), CAediting_1407690(17573986, +), CAediting_1407691(17574014, +), CAediting_1407692(17574016, +), CAediting_1407693(17574018, +), CAediting_1407694(17574034, +), CAediting_1407695(17574038, +), CAediting_1407696(17574040, +), CAediting_1407697(17574041, +), CAediting_1407698(17574042, +), CAediting_1407699(17574054, +), CAediting_1407700(17574058, +), CAediting_1407701(17574065, +), CAediting_1407702(17574081, +), CAediting_1407703(17574136, +), CAediting_1407704(17574149, +), CAediting_1407705(17574153, +), CAediting_1407706(17574606, +), CAediting_1407707(17574611, +), CAediting_1407708(17574632, +), CAediting_1407709(17574645, +), CAediting_1407710(17574647, +), CAediting_1407711(17574675, +), CAediting_1407712(17574676, +), CAediting_1407713(17574956, +), CAediting_1407714(17574957, +), CAediting_1407715(17574958, +), CAediting_1407716(17574969, +), CAediting_1407717(17574974, +), CAediting_1407718(17575045, +), CAediting_1407719(17575107, +), CAediting_1407720(17575121, +), CAediting_1407721(17575494, +), CAediting_1407722(17575502, +), CAediting_1407723(17575533, +), CAediting_1407724(17575550, +), CAediting_1407725(17575579, +), CAediting_1407726(17577550, +), CAediting_1407727(17578840, +), CAediting_1407728(17578841, +), CAediting_1407729(17579350, +), CAediting_1407730(17579431, +), CAediting_1407731(17579440, +), CAediting_1407732(17579567, +), CAediting_1407733(17580663, +), CAediting_1407734(17580668, +), CAediting_1407735(17580669, +), CAediting_1407736(17581278, +), CAediting_1407737(17581299, +), CAediting_1407738(17581387, +), CAediting_1407739(17581466, +), CAediting_1407740(17582172, +), CAediting_1407741(17582331, +), CAediting_1407742(17582353, +), CAediting_1407743(17583776, +), CAediting_1407744(17583792, +), CAediting_1407745(17583798, +), CAediting_1407746(17583806, +), CAediting_1407747(17583864, +), CAediting_1407748(17583911, +), CAediting_1407749(17583973, +), CAediting_1407750(17583974, +), CAediting_1407751(17584001, +), CAediting_1407752(17584558, +), CAediting_1407753(17584587, +), CAediting_1407754(17584607, +), CAediting_1407755(17587290, +), CAediting_1407756(17587341, +), CAediting_1407757(17587367, +), CAediting_1407758(17587392, +), CAediting_1407759(17587402, +), CAediting_1407760(17587420, +), CAediting_1407761(17588754, +), CAediting_1407762(17589340, +), CAediting_1407763(17589350, +), CAediting_1407764(17589457, +), CAediting_1407765(17589468, +), CAediting_1407766(17590852, +), CAediting_1407767(17590987, +), CAediting_1407768(17591028, +), CAediting_1407769(17592329, +), CAediting_1407770(17593943, +), CAediting_1407771(17597933, +), CAediting_1407772(17597936, +), CAediting_1407773(17598096, +), CAediting_1407774(17598105, +), CAediting_1407775(17598137, +), CAediting_1407776(17598138, +), CAediting_1407777(17598172, +), CAediting_1407778(17598180, +), CAediting_1407779(17598203, +), CAediting_1407780(17598210, +), CAediting_1407781(17598224, +), CAediting_1407782(17598248, +), CAediting_1407783(17598281, +), CAediting_1407784(17598494, +), CAediting_1407785(17598502, +), CAediting_1407786(17598933, +), CAediting_1407787(17598934, +), CAediting_1407788(17598966, +), CAediting_1407789(17598984, +), CAediting_1407790(17599001, +), CAediting_1407791(17599054, +), CAediting_1407792(17602952, +), CAediting_1407793(17603329, +), CAediting_1407794(17607177, +), CAediting_1407795(17607307, +), CAediting_1407796(17607561, +), CAediting_1407797(17607567, +), CAediting_1407798(17607905, +), CAediting_1407799(17608353, +), CAediting_1407800(17608374, +), CAediting_1407801(17608375, +), CAediting_1407802(17608401, +), CAediting_1407803(17608404, +), CAediting_1407804(17608468, +), CAediting_1407805(17608509, +), CAediting_1407806(17608545, +), CAediting_1407807(17608563, +), CAediting_1407808(17608568, +), CAediting_1407809(17608588, +), CAediting_1407810(17608602, +), CAediting_1407811(17608605, +), CAediting_1407812(17608606, +), CAediting_1407813(17609223, +), CAediting_1407814(17609225, +), CAediting_1407815(17609227, +), CAediting_1407816(17609235, +), CAediting_1407817(17609247, +), CAediting_1407818(17609252, +), CAediting_1407819(17609254, +), CAediting_1407820(17609267, +), CAediting_1407821(17609274, +), CAediting_1407822(17609307, +), CAediting_1407823(17609308, +), CAediting_1407824(17609330, +), CAediting_1407825(17609331, +), CAediting_1407826(17609343, +), CAediting_1407827(17609383, +),

Top

RNA editing positional annotations for DSTN using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1407686chr20_17573938_+intronic
CAediting_1407687chr20_17573950_+intronic
CAediting_1407688chr20_17573961_+intronic
CAediting_1407689chr20_17573971_+intronic
CAediting_1407690chr20_17573986_+intronic
CAediting_1407691chr20_17574014_+intronic
CAediting_1407692chr20_17574016_+intronic
CAediting_1407693chr20_17574018_+intronic
CAediting_1407694chr20_17574034_+intronic
CAediting_1407695chr20_17574038_+intronic
CAediting_1407696chr20_17574040_+intronic
CAediting_1407697chr20_17574041_+intronic
CAediting_1407698chr20_17574042_+intronic
CAediting_1407699chr20_17574054_+intronic
CAediting_1407700chr20_17574058_+intronic
CAediting_1407701chr20_17574065_+intronic
CAediting_1407702chr20_17574081_+intronic
CAediting_1407703chr20_17574136_+intronic
CAediting_1407704chr20_17574149_+intronic
CAediting_1407705chr20_17574153_+intronic
CAediting_1407706chr20_17574606_+intronic
CAediting_1407707chr20_17574611_+intronic
CAediting_1407708chr20_17574632_+intronic
CAediting_1407709chr20_17574645_+intronic
CAediting_1407710chr20_17574647_+intronic
CAediting_1407711chr20_17574675_+intronic
CAediting_1407712chr20_17574676_+intronic
CAediting_1407713chr20_17574956_+intronic
CAediting_1407714chr20_17574957_+intronic
CAediting_1407715chr20_17574958_+intronic
CAediting_1407716chr20_17574969_+intronic
CAediting_1407717chr20_17574974_+intronic
CAediting_1407718chr20_17575045_+intronic
CAediting_1407719chr20_17575107_+intronic
CAediting_1407720chr20_17575121_+intronic
CAediting_1407721chr20_17575494_+intronic
CAediting_1407722chr20_17575502_+intronic
CAediting_1407723chr20_17575533_+intronic
CAediting_1407724chr20_17575550_+intronic
CAediting_1407725chr20_17575579_+intronic
CAediting_1407726chr20_17577550_+intronic
CAediting_1407727chr20_17578840_+intronic
CAediting_1407728chr20_17578841_+intronic
CAediting_1407729chr20_17579350_+intronic
CAediting_1407730chr20_17579431_+intronic
CAediting_1407731chr20_17579440_+intronic
CAediting_1407732chr20_17579567_+intronic
CAediting_1407733chr20_17580663_+intronic
CAediting_1407734chr20_17580668_+intronic
CAediting_1407735chr20_17580669_+intronic
CAediting_1407736chr20_17581278_+intronic
CAediting_1407737chr20_17581299_+intronic
CAediting_1407738chr20_17581387_+intronic
CAediting_1407739chr20_17581466_+intronic
CAediting_1407740chr20_17582172_+intronic
CAediting_1407741chr20_17582331_+intronic
CAediting_1407742chr20_17582353_+intronic
CAediting_1407743chr20_17583776_+intronic
CAediting_1407744chr20_17583792_+intronic
CAediting_1407745chr20_17583798_+intronic
CAediting_1407746chr20_17583806_+intronic
CAediting_1407747chr20_17583864_+intronic
CAediting_1407748chr20_17583911_+intronic
CAediting_1407749chr20_17583973_+intronic
CAediting_1407750chr20_17583974_+intronic
CAediting_1407751chr20_17584001_+intronic
CAediting_1407752chr20_17584558_+intronic
CAediting_1407753chr20_17584587_+intronic
CAediting_1407754chr20_17584607_+intronic
CAediting_1407755chr20_17587290_+intronic
CAediting_1407756chr20_17587341_+intronic
CAediting_1407757chr20_17587367_+intronic
CAediting_1407758chr20_17587392_+intronic
CAediting_1407759chr20_17587402_+intronic
CAediting_1407760chr20_17587420_+intronic
CAediting_1407761chr20_17588754_+intronic
CAediting_1407762chr20_17589340_+intronic
CAediting_1407763chr20_17589350_+intronic
CAediting_1407764chr20_17589457_+intronic
CAediting_1407765chr20_17589468_+intronic
CAediting_1407766chr20_17590852_+intronic
CAediting_1407767chr20_17590987_+intronic
CAediting_1407768chr20_17591028_+intronic
CAediting_1407769chr20_17592329_+intronic
CAediting_1407770chr20_17593943_+intronic
CAediting_1407771chr20_17597933_+intronic
CAediting_1407772chr20_17597936_+intronic
CAediting_1407773chr20_17598096_+intronic
CAediting_1407774chr20_17598105_+intronic
CAediting_1407775chr20_17598137_+intronic
CAediting_1407776chr20_17598138_+intronic
CAediting_1407777chr20_17598172_+intronic
CAediting_1407778chr20_17598180_+intronic
CAediting_1407779chr20_17598203_+intronic
CAediting_1407780chr20_17598210_+intronic
CAediting_1407781chr20_17598224_+intronic
CAediting_1407782chr20_17598248_+intronic
CAediting_1407783chr20_17598281_+intronic
CAediting_1407784chr20_17598494_+intronic
CAediting_1407785chr20_17598502_+intronic
CAediting_1407786chr20_17598933_+intronic
CAediting_1407787chr20_17598934_+intronic
CAediting_1407788chr20_17598966_+intronic
CAediting_1407789chr20_17598984_+intronic
CAediting_1407790chr20_17599001_+intronic
CAediting_1407791chr20_17599054_+intronic
CAediting_1407792chr20_17602952_+intronic
CAediting_1407793chr20_17603329_+intronic
CAediting_1407794chr20_17607177_+UTR3
CAediting_1407795chr20_17607307_+UTR3
CAediting_1407796chr20_17607561_+UTR3
CAediting_1407797chr20_17607567_+UTR3
CAediting_1407798chr20_17607905_+UTR3
CAediting_1407799chr20_17608353_+UTR3
CAediting_1407800chr20_17608374_+UTR3
CAediting_1407801chr20_17608375_+UTR3
CAediting_1407802chr20_17608401_+UTR3
CAediting_1407803chr20_17608404_+UTR3
CAediting_1407804chr20_17608468_+UTR3
CAediting_1407805chr20_17608509_+UTR3
CAediting_1407806chr20_17608545_+UTR3
CAediting_1407807chr20_17608563_+UTR3
CAediting_1407808chr20_17608568_+UTR3
CAediting_1407809chr20_17608588_+UTR3
CAediting_1407810chr20_17608602_+UTR3
CAediting_1407811chr20_17608605_+UTR3
CAediting_1407812chr20_17608606_+UTR3
CAediting_1407813chr20_17609223_+UTR3
CAediting_1407814chr20_17609225_+UTR3
CAediting_1407815chr20_17609227_+UTR3
CAediting_1407816chr20_17609235_+UTR3
CAediting_1407817chr20_17609247_+UTR3
CAediting_1407818chr20_17609252_+UTR3
CAediting_1407819chr20_17609254_+UTR3
CAediting_1407820chr20_17609267_+UTR3
CAediting_1407821chr20_17609274_+UTR3
CAediting_1407822chr20_17609307_+UTR3
CAediting_1407823chr20_17609308_+UTR3
CAediting_1407824chr20_17609330_+UTR3
CAediting_1407825chr20_17609331_+UTR3
CAediting_1407826chr20_17609343_+UTR3
CAediting_1407827chr20_17609383_+UTR3

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1407686chr20_17573938_+SINEAluAluJr
CAediting_1407687chr20_17573950_+SINEAluAluJr
CAediting_1407688chr20_17573961_+SINEAluAluJr
CAediting_1407689chr20_17573971_+SINEAluAluJr
CAediting_1407690chr20_17573986_+SINEAluAluJr
CAediting_1407691chr20_17574014_+SINEAluAluJr
CAediting_1407692chr20_17574016_+SINEAluAluJr
CAediting_1407693chr20_17574018_+SINEAluAluJr
CAediting_1407694chr20_17574034_+SINEAluAluJr
CAediting_1407695chr20_17574038_+SINEAluAluJr
CAediting_1407696chr20_17574040_+SINEAluAluJr
CAediting_1407697chr20_17574041_+SINEAluAluJr
CAediting_1407698chr20_17574042_+SINEAluAluJr
CAediting_1407699chr20_17574054_+SINEAluAluJr
CAediting_1407700chr20_17574058_+SINEAluAluJr
CAediting_1407701chr20_17574065_+SINEAluAluJr
CAediting_1407702chr20_17574081_+SINEAluAluJr
CAediting_1407703chr20_17574136_+SINEAluAluJr
CAediting_1407704chr20_17574149_+SINEAluAluJr
CAediting_1407705chr20_17574153_+SINEAluAluJr
CAediting_1407706chr20_17574606_+SINEAluAluSx
CAediting_1407707chr20_17574611_+SINEAluAluSx
CAediting_1407708chr20_17574632_+SINEAluAluSx
CAediting_1407709chr20_17574645_+SINEAluAluSx
CAediting_1407710chr20_17574647_+SINEAluAluSx
CAediting_1407711chr20_17574675_+SINEAluAluSx
CAediting_1407712chr20_17574676_+SINEAluAluSx
CAediting_1407713chr20_17574956_+SINEAluAluJr
CAediting_1407714chr20_17574957_+SINEAluAluJr
CAediting_1407715chr20_17574958_+SINEAluAluJr
CAediting_1407716chr20_17574969_+SINEAluAluJr
CAediting_1407717chr20_17574974_+SINEAluAluJr
CAediting_1407718chr20_17575045_+SINEAluAluJr
CAediting_1407719chr20_17575107_+SINEAluAluJr
CAediting_1407720chr20_17575121_+SINEAluAluJr
CAediting_1407721chr20_17575494_+SINEAluAluJb
CAediting_1407722chr20_17575502_+SINEAluAluJb
CAediting_1407723chr20_17575533_+SINEAluAluJb
CAediting_1407724chr20_17575550_+SINEAluAluJb
CAediting_1407725chr20_17575579_+SINEAluAluJb
CAediting_1407726chr20_17577550_+SINEAluAluSx1
CAediting_1407727chr20_17578840_+SINEAluAluSp
CAediting_1407728chr20_17578841_+SINEAluAluSp
CAediting_1407729chr20_17579350_+SINEAluAluJo
CAediting_1407730chr20_17579431_+SINEAluAluJo
CAediting_1407731chr20_17579440_+SINEAluAluJo
CAediting_1407732chr20_17579567_+SINEAluAluJo
CAediting_1407733chr20_17580663_+SINEAluAluSq2
CAediting_1407734chr20_17580668_+SINEAluAluSq2
CAediting_1407735chr20_17580669_+SINEAluAluSq2
CAediting_1407736chr20_17581278_+SINEAluAluJr4
CAediting_1407737chr20_17581299_+SINEAluAluJr4
CAediting_1407738chr20_17581387_+SINEAluAluJr4
CAediting_1407739chr20_17581466_+SINEAluAluJr4
CAediting_1407740chr20_17582172_+SINEAluAluSx3
CAediting_1407741chr20_17582331_+SINEAluAluSx3
CAediting_1407742chr20_17582353_+SINEAluAluSx3
CAediting_1407743chr20_17583776_+SINEAluAluJr
CAediting_1407744chr20_17583792_+SINEAluAluJr
CAediting_1407745chr20_17583798_+SINEAluAluJr
CAediting_1407746chr20_17583806_+SINEAluAluJr
CAediting_1407747chr20_17583864_+SINEAluAluJr
CAediting_1407748chr20_17583911_+SINEAluAluJr
CAediting_1407749chr20_17583973_+SINEAluAluJr
CAediting_1407750chr20_17583974_+SINEAluAluJr
CAediting_1407751chr20_17584001_+SINEAluAluJr
CAediting_1407752chr20_17584558_+SINEAluAluSp
CAediting_1407753chr20_17584587_+SINEAluAluSp
CAediting_1407754chr20_17584607_+SINEAluAluSp
CAediting_1407755chr20_17587290_+SINEAluAluJb
CAediting_1407756chr20_17587341_+SINEAluAluJb
CAediting_1407757chr20_17587367_+SINEAluAluJb
CAediting_1407758chr20_17587392_+SINEAluAluJb
CAediting_1407759chr20_17587402_+SINEAluAluJb
CAediting_1407760chr20_17587420_+SINEAluAluJb
CAediting_1407761chr20_17588754_+SINEAluAluY
CAediting_1407762chr20_17589340_+SINEAluAluSx
CAediting_1407763chr20_17589350_+SINEAluAluSx
CAediting_1407764chr20_17589457_+SINEAluAluSx
CAediting_1407765chr20_17589468_+SINEAluAluSx
CAediting_1407766chr20_17590852_+SINEAluAluJr
CAediting_1407767chr20_17590987_+SINEAluAluJr
CAediting_1407768chr20_17591028_+SINEAluAluJr
CAediting_1407769chr20_17592329_+SINEAluAluJb
CAediting_1407770chr20_17593943_+SINEAluAluJr
CAediting_1407771chr20_17597933_+LINEL1L1MB7
CAediting_1407772chr20_17597936_+LINEL1L1MB7
CAediting_1407773chr20_17598096_+LINEL1L1MB7
CAediting_1407774chr20_17598105_+LINEL1L1MB7
CAediting_1407775chr20_17598137_+LINEL1L1MB7
CAediting_1407776chr20_17598138_+LINEL1L1MB7
CAediting_1407777chr20_17598172_+LINEL1L1MB7
CAediting_1407778chr20_17598180_+LINEL1L1MB7
CAediting_1407779chr20_17598203_+LINEL1L1MB7
CAediting_1407780chr20_17598210_+LINEL1L1MB7
CAediting_1407781chr20_17598224_+LINEL1L1MB7
CAediting_1407782chr20_17598248_+LINEL1L1MB7
CAediting_1407783chr20_17598281_+LINEL1L1MB7
CAediting_1407784chr20_17598494_+LINEL1L1MB7
CAediting_1407785chr20_17598502_+LINEL1L1MB7
CAediting_1407786chr20_17598933_+LINEL1L1M4
CAediting_1407787chr20_17598934_+LINEL1L1M4
CAediting_1407788chr20_17598966_+LINEL1L1M4
CAediting_1407789chr20_17598984_+LINEL1L1M4
CAediting_1407790chr20_17599001_+LINEL1L1M4
CAediting_1407791chr20_17599054_+LINEL1L1M4
CAediting_1407792chr20_17602952_+SINEAluAluSc
CAediting_1407793chr20_17603329_+DNATcMar-TiggerMER6B
CAediting_1407799chr20_17608353_+SINEAluAluJr
CAediting_1407800chr20_17608374_+SINEAluAluJr
CAediting_1407801chr20_17608375_+SINEAluAluJr
CAediting_1407802chr20_17608401_+SINEAluAluJr
CAediting_1407803chr20_17608404_+SINEAluAluJr
CAediting_1407804chr20_17608468_+SINEAluAluJr
CAediting_1407805chr20_17608509_+SINEAluAluJr
CAediting_1407806chr20_17608545_+SINEAluAluJr
CAediting_1407807chr20_17608563_+SINEAluAluJr
CAediting_1407808chr20_17608568_+SINEAluAluJr
CAediting_1407809chr20_17608588_+SINEAluAluJr
CAediting_1407810chr20_17608602_+SINEAluAluJr
CAediting_1407811chr20_17608605_+SINEAluAluJr
CAediting_1407812chr20_17608606_+SINEAluAluJr
CAediting_1407813chr20_17609223_+SINEAluAluJo
CAediting_1407814chr20_17609225_+SINEAluAluJo
CAediting_1407815chr20_17609227_+SINEAluAluJo
CAediting_1407816chr20_17609235_+SINEAluAluJo
CAediting_1407817chr20_17609247_+SINEAluAluJo
CAediting_1407818chr20_17609252_+SINEAluAluJo
CAediting_1407819chr20_17609254_+SINEAluAluJo
CAediting_1407820chr20_17609267_+SINEAluAluJo
CAediting_1407821chr20_17609274_+SINEAluAluJo
CAediting_1407822chr20_17609307_+SINEAluAluJo
CAediting_1407823chr20_17609308_+SINEAluAluJo
CAediting_1407824chr20_17609330_+SINEAluAluJo
CAediting_1407825chr20_17609331_+SINEAluAluJo
CAediting_1407826chr20_17609343_+SINEAluAluJo

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RNA A-to-I editing events in the alternative splicing sites for DSTN

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000125868.14.DSTN.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000125868.14.DSTN.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for DSTN

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
PRAD.CAediting_1407818.ENSG00000125868.DSTN.png
Soverview
SARC.CAediting_1407818.ENSG00000125868.DSTN.png
Soverview
STAD.CAediting_1407818.ENSG00000125868.DSTN.png
Soverview

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Protein coding region RNA A-to-I editings for DSTN

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for DSTN

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1407798chr20_17607905_+ENSG00000125868.14ENST00000246069hsa-miR-26b-3p17607903176079108mer-1a1760789217607910150.00-10.60
CAediting_1407798chr20_17607905_+ENSG00000125868.14ENST00000474024hsa-miR-26b-3p17607903176079108mer-1a1760789217607910150.00-10.60
CAediting_1407809chr20_17608588_+ENSG00000125868.14ENST00000246069hsa-miR-197217608587176085926mer1760857117608593146.00-31.44
CAediting_1407809chr20_17608588_+ENSG00000125868.14ENST00000246069hsa-miR-197217608587176085926mer1760857117608593146.00-31.44
CAediting_1407809chr20_17608588_+ENSG00000125868.14ENST00000246069hsa-miR-4743-5p17608584176085907mer-m81760857217608591152.00-28.17
CAediting_1407815chr20_17609227_+ENSG00000125868.14ENST00000246069hsa-miR-340-3p17609221176092277mer-m81760920717609228146.00-19.58
CAediting_1407815chr20_17609227_+ENSG00000125868.14ENST00000246069hsa-miR-6827-3p17609221176092277mer-m81760920817609228140.00-14.58
CAediting_1407817chr20_17609247_+ENSG00000125868.14ENST00000246069hsa-miR-3940-3p17609244176092518mer-1a1760923017609251140.00-14.58
CAediting_1407818chr20_17609252_+ENSG00000125868.14ENST00000246069hsa-miR-508-5p17609249176092557mer-m81760923217609256141.00-18.97
CAediting_1407818chr20_17609252_+ENSG00000125868.14ENST00000246069hsa-miR-6512-3p17609247176092537mer-m81760923317609254140.00-17.21
CAediting_1407818chr20_17609252_+ENSG00000125868.14ENST00000246069hsa-miR-6720-5p17609247176092537mer-m81760923317609254146.00-21.37
CAediting_1407818chr20_17609252_+ENSG00000125868.14ENST00000246069hsa-miR-6849-3p17609246176092538mer-1a1760923217609253147.00-15.97
CAediting_1407818chr20_17609252_+ENSG00000125868.14ENST00000246069hsa-miR-766-3p17609248176092547mer-m81760923417609255145.00-17.87
CAediting_1407826chr20_17609343_+ENSG00000125868.14ENST00000246069hsa-miR-470517609336176093427mer-m81760932417609343146.00-9.14
CAediting_1407799chr20_17608353_+ENSG00000125868.14ENST00000246069hsa-miR-500b-3p17608349176083557mer-m81760833717608356152.00-18.72
CAediting_1407800chr20_17608374_+ENSG00000125868.14ENST00000246069hsa-miR-513a-5p17608368176083747mer-m81760835817608375148.00-20.07
CAediting_1407800chr20_17608374_+ENSG00000125868.14ENST00000246069hsa-miR-513a-5p17608368176083747mer-m81760835817608375148.00-20.07
CAediting_1407800chr20_17608374_+ENSG00000125868.14ENST00000246069hsa-miR-63817608373176083797mer-1a1760835517608379151.00-32.33
CAediting_1407801chr20_17608375_+ENSG00000125868.14ENST00000246069hsa-miR-319917608373176083797mer-1a1760836017608379141.00-22.83
CAediting_1407801chr20_17608375_+ENSG00000125868.14ENST00000246069hsa-miR-319917608373176083797mer-1a1760836017608379141.00-22.83
CAediting_1407803chr20_17608404_+ENSG00000125868.14ENST00000246069hsa-miR-6780b-3p17608399176084046mer1760838417608405149.00-28.26
CAediting_1407803chr20_17608404_+ENSG00000125868.14ENST00000246069hsa-miR-6841-3p17608398176084036mer1760838417608404142.00-20.70
CAediting_1407805chr20_17608509_+ENSG00000125868.14ENST00000246069hsa-miR-181a-2-3p17608503176085097mer-m81760849017608510153.00-22.10
CAediting_1407807chr20_17608563_+ENSG00000125868.14ENST00000246069hsa-miR-1224-3p17608557176085637mer-m81760854417608564155.00-25.78
CAediting_1407807chr20_17608563_+ENSG00000125868.14ENST00000246069hsa-miR-4690-3p17608560176085678mer-1a1760854617608567154.00-22.91
CAediting_1407807chr20_17608563_+ENSG00000125868.14ENST00000246069hsa-miR-568517608560176085678mer-1a1760854617608567142.00-21.32
CAediting_1407808chr20_17608568_+ENSG00000125868.14ENST00000246069hsa-miR-426717608561176085677mer-m81760855317608568141.00-17.83
CAediting_1407808chr20_17608568_+ENSG00000125868.14ENST00000246069hsa-miR-797717608563176085697mer-m81760855217608570145.00-19.06
CAediting_1407810chr20_17608602_+ENSG00000125868.14ENST00000246069hsa-miR-339-5p17608596176086027mer-m81760858117608603167.00-27.25
CAediting_1407810chr20_17608602_+ENSG00000125868.14ENST00000246069hsa-miR-874-3p17608598176086058mer-1a1760858317608605147.00-20.00
CAediting_1407813chr20_17609223_+ENSG00000125868.14ENST00000246069hsa-miR-4433b-5p17609220176092267mer-m81760920717609227140.00-13.05
CAediting_1407814chr20_17609225_+ENSG00000125868.14ENST00000246069hsa-miR-6747-3p17609222176092287mer-m81760920917609229141.00-15.89
CAediting_1407814chr20_17609225_+ENSG00000125868.14ENST00000246069hsa-miR-6752-3p17609223176092297mer-m81760921017609230146.00-15.92
CAediting_1407823chr20_17609308_+ENSG00000125868.14ENST00000246069hsa-miR-3692-5p17609301176093077mer-m81760927817609308156.00-30.68
CAediting_1407823chr20_17609308_+ENSG00000125868.14ENST00000246069hsa-miR-370-3p17609302176093087mer-m81760928817609309156.00-25.23
CAediting_1407823chr20_17609308_+ENSG00000125868.14ENST00000246069hsa-miR-6893-3p17609302176093087mer-m81760928817609309140.00-14.42
CAediting_1407824chr20_17609330_+ENSG00000125868.14ENST00000246069hsa-miR-3059-3p17609325176093317mer-m81760931217609332153.00-20.40
CAediting_1407824chr20_17609330_+ENSG00000125868.14ENST00000246069hsa-miR-568417609326176093327mer-m81760931417609333140.00-12.42
CAediting_1407796chr20_17607561_+ENSG00000125868.14ENST00000246069hsa-miR-5001-3p17607559176075668mer-1a1760754517607566153.00-17.83
CAediting_1407796chr20_17607561_+ENSG00000125868.14ENST00000474024hsa-miR-5001-3p17607559176075668mer-1a1760754517607566153.00-17.83
CAediting_1407797chr20_17607567_+ENSG00000125868.14ENST00000246069hsa-miR-3664-5p17607562176075687mer-1a1760754817607568141.00-15.56
CAediting_1407797chr20_17607567_+ENSG00000125868.14ENST00000246069hsa-miR-6728-3p17607560176075667mer-m81760754717607567154.00-18.56
CAediting_1407797chr20_17607567_+ENSG00000125868.14ENST00000474024hsa-miR-3664-5p17607562176075687mer-1a1760754817607568141.00-15.56
CAediting_1407797chr20_17607567_+ENSG00000125868.14ENST00000474024hsa-miR-6728-3p17607560176075667mer-m81760754717607567154.00-18.56

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1407800chr20_17608374_+ENSG00000125868.14ENST00000246069hsa-miR-10399-5p17608369176083757mer-m81760835517608376148-9.71
CAediting_1407801chr20_17608375_+ENSG00000125868.14ENST00000246069hsa-miR-10399-5p17608369176083757mer-m81760835517608376148-9.71
CAediting_1407815chr20_17609227_+ENSG00000125868.14ENST00000246069hsa-miR-10a-5p17609224176092307mer-m81760921117609231142-12.31
CAediting_1407815chr20_17609227_+ENSG00000125868.14ENST00000246069hsa-miR-10b-5p17609224176092307mer-m81760920517609231148-15.56
CAediting_1407806chr20_17608545_+ENSG00000125868.14ENST00000246069hsa-miR-1245a17608540176085467mer-m81760852717608547145-18.36
CAediting_1407818chr20_17609252_+ENSG00000125868.14ENST00000246069hsa-miR-1251-5p17609248176092547mer-m81760923217609255144-15.81
CAediting_1407819chr20_17609254_+ENSG00000125868.14ENST00000246069hsa-miR-1251-5p17609248176092547mer-m81760923217609255144-15.81
CAediting_1407818chr20_17609252_+ENSG00000125868.14ENST00000246069hsa-miR-1287-3p17609247176092537mer-m81760923117609254143-19.67
CAediting_1407819chr20_17609254_+ENSG00000125868.14ENST00000246069hsa-miR-1287-3p17609247176092537mer-m81760923117609254143-19.67
CAediting_1407809chr20_17608588_+ENSG00000125868.14ENST00000246069hsa-miR-3135b17608583176085897mer-m81760857317608590155-29.39
CAediting_1407802chr20_17608401_+ENSG00000125868.14ENST00000246069hsa-miR-3152-5p17608395176084017mer-m81760837917608402153-16.3
CAediting_1407799chr20_17608353_+ENSG00000125868.14ENST00000246069hsa-miR-3157-5p17608346176083527mer-m81760833217608353148-18.11
CAediting_1407823chr20_17609308_+ENSG00000125868.14ENST00000246069hsa-miR-318817609306176093127mer-m81760929117609313147-21.19
CAediting_1407820chr20_17609267_+ENSG00000125868.14ENST00000246069hsa-miR-32-5p17609262176092687mer-m81760924717609269144-12.36
CAediting_1407820chr20_17609267_+ENSG00000125868.14ENST00000246069hsa-miR-363-3p17609262176092687mer-m81760924817609269149-12.29
CAediting_1407809chr20_17608588_+ENSG00000125868.14ENST00000246069hsa-miR-365217608584176085907mer-m81760857417608591145-19.5
CAediting_1407816chr20_17609235_+ENSG00000125868.14ENST00000246069hsa-miR-367217609229176092346mer1760921117609235141-16.23
CAediting_1407813chr20_17609223_+ENSG00000125868.14ENST00000246069hsa-miR-371b-5p17609217176092248mer-1a1760920017609224155-16.1
CAediting_1407813chr20_17609223_+ENSG00000125868.14ENST00000246069hsa-miR-373-5p17609217176092248mer-1a1760920317609224140-10.37
CAediting_1407811chr20_17608605_+ENSG00000125868.14ENST00000246069hsa-miR-431-5p17608602176086087mer-m81760859117608609151-17.68
CAediting_1407812chr20_17608606_+ENSG00000125868.14ENST00000246069hsa-miR-431-5p17608602176086087mer-m81760859117608609151-17.68
CAediting_1407814chr20_17609225_+ENSG00000125868.14ENST00000246069hsa-miR-442117609222176092287mer-m81760920817609229155-16.7
CAediting_1407815chr20_17609227_+ENSG00000125868.14ENST00000246069hsa-miR-442117609222176092287mer-m81760920817609229155-16.7
CAediting_1407817chr20_17609247_+ENSG00000125868.14ENST00000246069hsa-miR-4665-5p17609240176092467mer-m81760922417609247155-27.54
CAediting_1407815chr20_17609227_+ENSG00000125868.14ENST00000246069hsa-miR-4725-5p17609225176092317mer-m81760921217609232140-15.96
CAediting_1407797chr20_17607567_+ENSG00000125868.14ENST00000246069hsa-miR-4778-5p17607562176075687mer-1a1760754117607568142-17.31
CAediting_1407794chr20_17607177_+ENSG00000125868.14ENST00000246069hsa-miR-4802-3p17607173176071797mer-m81760716217607180148-13.23
CAediting_1407815chr20_17609227_+ENSG00000125868.14ENST00000246069hsa-miR-504-5p17609225176092317mer-m81760921317609232147-18.15
CAediting_1407799chr20_17608353_+ENSG00000125868.14ENST00000246069hsa-miR-512-5p17608348176083547mer-m81760833317608355145-21.03
CAediting_1407799chr20_17608353_+ENSG00000125868.14ENST00000246069hsa-miR-512-5p17608348176083547mer-m81760833317608355145-21.03
CAediting_1407810chr20_17608602_+ENSG00000125868.14ENST00000246069hsa-miR-569117608598176086058mer-1a1760858417608605149-19.57
CAediting_1407811chr20_17608605_+ENSG00000125868.14ENST00000246069hsa-miR-569117608598176086058mer-1a1760858417608605149-19.57
CAediting_1407814chr20_17609225_+ENSG00000125868.14ENST00000246069hsa-miR-5699-3p17609222176092287mer-m81760920817609229141-16.39
CAediting_1407815chr20_17609227_+ENSG00000125868.14ENST00000246069hsa-miR-5699-3p17609222176092287mer-m81760920817609229141-16.39
CAediting_1407809chr20_17608588_+ENSG00000125868.14ENST00000246069hsa-miR-578717608585176085906mer1760857217608591140-25.14
CAediting_1407794chr20_17607177_+ENSG00000125868.14ENST00000246069hsa-miR-607917607170176071767mer-m81760715417607177150-14.06
CAediting_1407813chr20_17609223_+ENSG00000125868.14ENST00000246069hsa-miR-616-5p17609217176092248mer-1a1760920317609224140-12.1
CAediting_1407817chr20_17609247_+ENSG00000125868.14ENST00000246069hsa-miR-63717609241176092477mer-m81760922217609248144-26.41
CAediting_1407800chr20_17608374_+ENSG00000125868.14ENST00000246069hsa-miR-6504-3p17608369176083757mer-m81760835517608376153-14.48
CAediting_1407801chr20_17608375_+ENSG00000125868.14ENST00000246069hsa-miR-6504-3p17608369176083757mer-m81760835517608376153-14.48
CAediting_1407817chr20_17609247_+ENSG00000125868.14ENST00000246069hsa-miR-66117609243176092497mer-m81760922717609250140-17.5
CAediting_1407808chr20_17608568_+ENSG00000125868.14ENST00000246069hsa-miR-6787-3p17608562176085698mer-1a1760855017608569147-20.17
CAediting_1407810chr20_17608602_+ENSG00000125868.14ENST00000246069hsa-miR-6805-3p17608598176086058mer-1a1760858317608605146-18.25
CAediting_1407811chr20_17608605_+ENSG00000125868.14ENST00000246069hsa-miR-6805-3p17608598176086058mer-1a1760858317608605146-18.25
CAediting_1407817chr20_17609247_+ENSG00000125868.14ENST00000246069hsa-miR-6852-5p17609242176092487mer-m81760922817609249146-20.84
CAediting_1407817chr20_17609247_+ENSG00000125868.14ENST00000246069hsa-miR-7109-5p17609241176092466mer1760922317609247154-40.35
CAediting_1407805chr20_17608509_+ENSG00000125868.14ENST00000246069hsa-miR-805217608508176085147mer-1a1760849217608514143-20.14
CAediting_1407803chr20_17608404_+ENSG00000125868.14ENST00000246069hsa-miR-990317608402176084087mer-m81760839117608409144-14.24
CAediting_1407797chr20_17607567_+ENSG00000125868.14ENST00000474024hsa-miR-4778-5p17607562176075687mer-1a1760754117607568142-17.31
CAediting_1407794chr20_17607177_+ENSG00000125868.14ENST00000474024hsa-miR-4802-3p17607173176071797mer-m81760716217607180148-13.23
CAediting_1407794chr20_17607177_+ENSG00000125868.14ENST00000474024hsa-miR-607917607170176071767mer-m81760715417607177150-14.06
CAediting_1407794chr20_17607177_+ENSG00000125868.14ENST00000449141hsa-miR-4802-3p17607173176071797mer-m81760716217607180148-13.23
CAediting_1407794chr20_17607177_+ENSG00000125868.14ENST00000449141hsa-miR-607917607170176071767mer-m81760715417607177150-14.06

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_393chr1_1167164_+ENSG00000125868.14ENST00000246069hsa-miR-200b-3p17608378176083847mer-m81760836417608385140-9.41
CAediting_393chr1_1167164_+ENSG00000125868.14ENST00000246069hsa-miR-200b-3p17608808176088136mer1760879217608814141-14.74
CAediting_393chr1_1167164_+ENSG00000125868.14ENST00000246069hsa-miR-200b-3p17607473176074797mer-m81760745717607480155-16.96
CAediting_393chr1_1167164_+ENSG00000125868.14ENST00000474024hsa-miR-200b-3p17607473176074797mer-m81760745717607480155-16.96
CAediting_1229415chr17_67471547_+ENSG00000125868.14ENST00000246069hsa-miR-548aa17608207176082148mer-1a1760819017608214157-14.85
CAediting_228905chr2_188297554_+ENSG00000125868.14ENST00000246069hsa-miR-561-3p17609289176092946mer1760927217609295145-14.79
CAediting_573001chr7_92204086_-ENSG00000125868.14ENST00000246069hsa-miR-1285-5p17609089176090968mer-1a1760907617609096140-16.52
CAediting_1229415chr17_67471547_+ENSG00000125868.14ENST00000474024hsa-miR-548aa17608207176082148mer-1a1760819017608214157-14.85
CAediting_414656chr5_72878640_+ENSG00000125868.14ENST00000449141hsa-miR-4804-3p17607051176070588mer-1a1760703817607058147-11.79

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1160181chr17_7017644_-ENSG00000125868.14ENST00000246069hsa-miR-195-3p17607910176079178mer-1a1760789817607917147-9.16
CAediting_1160181chr17_7017644_-ENSG00000125868.14ENST00000246069hsa-miR-195-3p17607996176080038mer-1a1760798117608003148-10.72
CAediting_393chr1_1167164_+ENSG00000125868.14ENST00000246069hsa-miR-200b-3p17608201176082077mer-m81760818517608208151-12.64
CAediting_393chr1_1167164_+ENSG00000125868.14ENST00000246069hsa-miR-200b-3p17608936176089427mer-m81760892317608943155-15.59
CAediting_1351755chr19_40282625_-ENSG00000125868.14ENST00000246069hsa-miR-64117607581176075877mer-m81760756517607588154-14.37
CAediting_1351755chr19_40282625_-ENSG00000125868.14ENST00000246069hsa-miR-64117607813176078186mer1760779717607819140-14.22
CAediting_1160181chr17_7017644_-ENSG00000125868.14ENST00000474024hsa-miR-195-3p17607910176079178mer-1a1760789817607917147-9.16
CAediting_1160181chr17_7017644_-ENSG00000125868.14ENST00000474024hsa-miR-195-3p17607996176080038mer-1a1760798117608003148-10.72
CAediting_393chr1_1167164_+ENSG00000125868.14ENST00000474024hsa-miR-200b-3p17608201176082077mer-m81760818517608208151-12.64

check button Differentially expressed gene-miRNA network
boxplot

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The effects of the RNA editing to the stability of the RNA structures for DSTN

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for DSTN

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
BRCACAediting_1407816chr20_17609235_+0.006498112950938330.303766103045645....
THCACAediting_1407816chr20_17609235_+0.04168161354422750.249565109235397..0.008235887679690750.320277500928587
SARCCAediting_1407816chr20_17609235_+0.001628534533521450.418675228119681....
LGGCAediting_1407818chr20_17609252_+0.0417483533500550.1802518430769568.38111476555005e-120.5572693455588970.03806586705717190.183570066166132
BRCACAediting_1407818chr20_17609252_+0.008409097459532220.319467495278235....
STADCAediting_1407818chr20_17609252_+..1.04512866141064e-050.579282384960832..
SARCCAediting_1407818chr20_17609252_+0.004055729544466970.395657352172329....
BRCACAediting_1407825chr20_17609331_+0.0001749111421097780.363275810491296....
PRADCAediting_1407825chr20_17609331_+0.01252679248158670.19762306312708....
PCPGCAediting_1407825chr20_17609331_+4.84875927075374e-050.527957445357335....

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Relation with cancer stages for DSTN

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for DSTN

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
LGGCAediting_1407822chr20_17609307_+0.03838631115702910.03664351074.22

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RelatedDrugs for DSTN

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for DSTN

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
DSTNC0018801Heart failure1CTD_human
DSTNC0018802Congestive heart failure1CTD_human
DSTNC0023212Left-Sided Heart Failure1CTD_human
DSTNC0235527Heart Failure, Right-Sided1CTD_human
DSTNC0600519Ventricular Remodeling1CTD_human
DSTNC0600520Left Ventricle Remodeling1CTD_human
DSTNC1959583Myocardial Failure1CTD_human
DSTNC1961112Heart Decompensation1CTD_human