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Editing gene: METAP2 (CAeditome ID:10988)

Gene summary for METAP2

Gene summary

Gene information	Gene symbol	METAP2
	Gene ID	10988
	Gene name	methionyl aminopeptidase 2
	Synonyms	MAP2\|MNPEP\|p67eIF2
	Cytomap	12q22
	Type of gene	protein-coding
	Description	methionine aminopeptidase 2eIF-2-associated p67 homologinitiation factor 2-associated 67 kDa glycoproteinpeptidase M 2testicular tissue protein Li 17
	Modification date	20210518
	UniProtAcc	P50579
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
METAP2	GO:0004177	Methionine aminopeptidase 2	8858118
METAP2	GO:0008235	Methionine aminopeptidase 2	8858118
METAP2	GO:0016485	Methionine aminopeptidase 2	8858118
METAP2	GO:0018206	Methionine aminopeptidase 2	8858118
METAP2	GO:0031365	Methionine aminopeptidase 2	8858118
METAP2	GO:0005737	Methionine aminopeptidase 2	15102683
METAP2	GO:0005829	Methionine aminopeptidase 2	0000052
METAP2	GO:0005886	Methionine aminopeptidase 2	0000052

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RNA A-to-I events for METAP2

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000111142.12

RNA A-to-I editing events in Cancer.

CAediting_915142(95476245, +), CAediting_915143(95476251, +), CAediting_915144(95476257, +), CAediting_915145(95476287, +), CAediting_915146(95476291, +), CAediting_915147(95476292, +), CAediting_915148(95476321, +), CAediting_915149(95476331, +), CAediting_915150(95476336, +), CAediting_915151(95476391, +), CAediting_915152(95476392, +), CAediting_915153(95476397, +), CAediting_915154(95476398, +), CAediting_915155(95476400, +), CAediting_915156(95476401, +), CAediting_915157(95476408, +), CAediting_915158(95476409, +), CAediting_915159(95476414, +), CAediting_915160(95476457, +), CAediting_915161(95476462, +), CAediting_915162(95476464, +), CAediting_915163(95476469, +), CAediting_915164(95477154, +), CAediting_915165(95477197, +), CAediting_915166(95477227, +), CAediting_915167(95477263, +), CAediting_915168(95478353, +), CAediting_915169(95478362, +), CAediting_915170(95478376, +), CAediting_915171(95478611, +), CAediting_915172(95481155, +), CAediting_915173(95481175, +), CAediting_915174(95481177, +), CAediting_915175(95481178, +), CAediting_915176(95481264, +), CAediting_915177(95481268, +), CAediting_915178(95481304, +), CAediting_915179(95481331, +), CAediting_915180(95481339, +), CAediting_915181(95482189, +), CAediting_915182(95482209, +), CAediting_915183(95482237, +), CAediting_915184(95482241, +), CAediting_915185(95482259, +), CAediting_915186(95482261, +), CAediting_915187(95482302, +), CAediting_915188(95482310, +), CAediting_915189(95482333, +), CAediting_915190(95482348, +), CAediting_915191(95482365, +), CAediting_915192(95482387, +), CAediting_915193(95482524, +), CAediting_915194(95482525, +), CAediting_915195(95482530, +), CAediting_915196(95482545, +), CAediting_915197(95482546, +), CAediting_915198(95482554, +), CAediting_915199(95482555, +), CAediting_915200(95482559, +), CAediting_915201(95482578, +), CAediting_915202(95482592, +), CAediting_915203(95482593, +), CAediting_915204(95482634, +), CAediting_915205(95482635, +), CAediting_915206(95482636, +), CAediting_915207(95482655, +), CAediting_915208(95482659, +), CAediting_915209(95482666, +), CAediting_915210(95482711, +), CAediting_915211(95482713, +), CAediting_915212(95482780, +), CAediting_915213(95482932, +), CAediting_915214(95482984, +), CAediting_915215(95483010, +), CAediting_915216(95483382, +), CAediting_915217(95483401, +), CAediting_915218(95483402, +), CAediting_915219(95483412, +), CAediting_915220(95483420, +), CAediting_915221(95483421, +), CAediting_915222(95483426, +), CAediting_915223(95486597, +), CAediting_915224(95486598, +), CAediting_915225(95486627, +), CAediting_915226(95486637, +), CAediting_915227(95486680, +), CAediting_915228(95486725, +), CAediting_915229(95486731, +), CAediting_915230(95486758, +), CAediting_915231(95486759, +), CAediting_915232(95488222, +), CAediting_915233(95488271, +), CAediting_915234(95488285, +), CAediting_915235(95488290, +), CAediting_915236(95488299, +), CAediting_915237(95488314, +), CAediting_915238(95488322, +), CAediting_915239(95488362, +), CAediting_915240(95488388, +), CAediting_915241(95488389, +), CAediting_915242(95488394, +), CAediting_915243(95488415, +), CAediting_915244(95488429, +), CAediting_915245(95488432, +), CAediting_915246(95488459, +), CAediting_915247(95490153, +), CAediting_915248(95490259, +), CAediting_915249(95492635, +), CAediting_915250(95492695, +), CAediting_915251(95493221, +), CAediting_915252(95493361, +), CAediting_915253(95493401, +), CAediting_915254(95493404, +), CAediting_915255(95498756, +), CAediting_915256(95498758, +), CAediting_915257(95498807, +), CAediting_915258(95498828, +), CAediting_915259(95498835, +), CAediting_915260(95498961, +), CAediting_915261(95498968, +), CAediting_915262(95499245, +), CAediting_915263(95499323, +), CAediting_915264(95499338, +), CAediting_915265(95499393, +), CAediting_915266(95501037, +), CAediting_915267(95501081, +), CAediting_915268(95501159, +), CAediting_915269(95501568, +), CAediting_915270(95501572, +), CAediting_915271(95501600, +), CAediting_915272(95501608, +), CAediting_915273(95505919, +),

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RNA editing positional annotations for METAP2 using Annovar

Protein coding RNA editing(s).

CAeditome ID	Position	Variant type	ENST	NTchange	AAchange	SIFT_score	Polyphen2_HVAR_score	PROVEAN_pred
CAediting_915181	chr12_95482189_+	nonsynonymous SNV	ENST00000549502.4	c.A322G	p.S108G	D	.	N

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_915142	chr12_95476245_+	ncRNA_intronic
CAediting_915143	chr12_95476251_+	ncRNA_intronic
CAediting_915144	chr12_95476257_+	ncRNA_intronic
CAediting_915145	chr12_95476287_+	ncRNA_intronic
CAediting_915146	chr12_95476291_+	ncRNA_intronic
CAediting_915147	chr12_95476292_+	ncRNA_intronic
CAediting_915148	chr12_95476321_+	ncRNA_intronic
CAediting_915149	chr12_95476331_+	ncRNA_intronic
CAediting_915150	chr12_95476336_+	ncRNA_intronic
CAediting_915151	chr12_95476391_+	ncRNA_intronic
CAediting_915152	chr12_95476392_+	ncRNA_intronic
CAediting_915153	chr12_95476397_+	ncRNA_intronic
CAediting_915154	chr12_95476398_+	ncRNA_intronic
CAediting_915155	chr12_95476400_+	ncRNA_intronic
CAediting_915156	chr12_95476401_+	ncRNA_intronic
CAediting_915157	chr12_95476408_+	ncRNA_intronic
CAediting_915158	chr12_95476409_+	ncRNA_intronic
CAediting_915159	chr12_95476414_+	ncRNA_intronic
CAediting_915160	chr12_95476457_+	ncRNA_intronic
CAediting_915161	chr12_95476462_+	ncRNA_intronic
CAediting_915162	chr12_95476464_+	ncRNA_intronic
CAediting_915163	chr12_95476469_+	ncRNA_intronic
CAediting_915164	chr12_95477154_+	ncRNA_intronic
CAediting_915165	chr12_95477197_+	ncRNA_intronic
CAediting_915166	chr12_95477227_+	ncRNA_intronic
CAediting_915167	chr12_95477263_+	ncRNA_intronic
CAediting_915168	chr12_95478353_+	ncRNA_intronic
CAediting_915169	chr12_95478362_+	ncRNA_intronic
CAediting_915170	chr12_95478376_+	ncRNA_intronic
CAediting_915171	chr12_95478611_+	ncRNA_intronic
CAediting_915172	chr12_95481155_+	ncRNA_intronic
CAediting_915173	chr12_95481175_+	ncRNA_intronic
CAediting_915174	chr12_95481177_+	ncRNA_intronic
CAediting_915175	chr12_95481178_+	ncRNA_intronic
CAediting_915176	chr12_95481264_+	ncRNA_intronic
CAediting_915177	chr12_95481268_+	ncRNA_intronic
CAediting_915178	chr12_95481304_+	ncRNA_intronic
CAediting_915179	chr12_95481331_+	ncRNA_intronic
CAediting_915180	chr12_95481339_+	ncRNA_intronic
CAediting_915181	chr12_95482189_+	exonic
CAediting_915182	chr12_95482209_+	exonic
CAediting_915183	chr12_95482237_+	ncRNA_intronic
CAediting_915184	chr12_95482241_+	ncRNA_intronic
CAediting_915185	chr12_95482259_+	ncRNA_intronic
CAediting_915186	chr12_95482261_+	ncRNA_intronic
CAediting_915187	chr12_95482302_+	ncRNA_intronic
CAediting_915188	chr12_95482310_+	ncRNA_intronic
CAediting_915189	chr12_95482333_+	ncRNA_intronic
CAediting_915190	chr12_95482348_+	ncRNA_intronic
CAediting_915191	chr12_95482365_+	ncRNA_intronic
CAediting_915192	chr12_95482387_+	ncRNA_intronic
CAediting_915193	chr12_95482524_+	ncRNA_intronic
CAediting_915194	chr12_95482525_+	ncRNA_intronic
CAediting_915195	chr12_95482530_+	ncRNA_intronic
CAediting_915196	chr12_95482545_+	ncRNA_intronic
CAediting_915197	chr12_95482546_+	ncRNA_intronic
CAediting_915198	chr12_95482554_+	ncRNA_intronic
CAediting_915199	chr12_95482555_+	ncRNA_intronic
CAediting_915200	chr12_95482559_+	ncRNA_intronic
CAediting_915201	chr12_95482578_+	ncRNA_intronic
CAediting_915202	chr12_95482592_+	ncRNA_intronic
CAediting_915203	chr12_95482593_+	ncRNA_intronic
CAediting_915204	chr12_95482634_+	ncRNA_intronic
CAediting_915205	chr12_95482635_+	ncRNA_intronic
CAediting_915206	chr12_95482636_+	ncRNA_intronic
CAediting_915207	chr12_95482655_+	ncRNA_intronic
CAediting_915208	chr12_95482659_+	ncRNA_intronic
CAediting_915209	chr12_95482666_+	ncRNA_intronic
CAediting_915210	chr12_95482711_+	ncRNA_intronic
CAediting_915211	chr12_95482713_+	ncRNA_intronic
CAediting_915212	chr12_95482780_+	ncRNA_intronic
CAediting_915213	chr12_95482932_+	ncRNA_intronic
CAediting_915214	chr12_95482984_+	ncRNA_intronic
CAediting_915215	chr12_95483010_+	ncRNA_intronic
CAediting_915216	chr12_95483382_+	ncRNA_exonic
CAediting_915217	chr12_95483401_+	ncRNA_exonic
CAediting_915218	chr12_95483402_+	ncRNA_exonic
CAediting_915219	chr12_95483412_+	ncRNA_exonic
CAediting_915220	chr12_95483420_+	ncRNA_exonic
CAediting_915221	chr12_95483421_+	ncRNA_exonic
CAediting_915222	chr12_95483426_+	ncRNA_exonic
CAediting_915223	chr12_95486597_+	ncRNA_intronic
CAediting_915224	chr12_95486598_+	ncRNA_intronic
CAediting_915225	chr12_95486627_+	ncRNA_intronic
CAediting_915226	chr12_95486637_+	ncRNA_intronic
CAediting_915227	chr12_95486680_+	ncRNA_intronic
CAediting_915228	chr12_95486725_+	ncRNA_intronic
CAediting_915229	chr12_95486731_+	ncRNA_intronic
CAediting_915230	chr12_95486758_+	ncRNA_intronic
CAediting_915231	chr12_95486759_+	ncRNA_intronic
CAediting_915232	chr12_95488222_+	ncRNA_intronic
CAediting_915233	chr12_95488271_+	ncRNA_intronic
CAediting_915234	chr12_95488285_+	ncRNA_intronic
CAediting_915235	chr12_95488290_+	ncRNA_intronic
CAediting_915236	chr12_95488299_+	ncRNA_intronic
CAediting_915237	chr12_95488314_+	ncRNA_intronic
CAediting_915238	chr12_95488322_+	ncRNA_intronic
CAediting_915239	chr12_95488362_+	ncRNA_intronic
CAediting_915240	chr12_95488388_+	ncRNA_intronic
CAediting_915241	chr12_95488389_+	ncRNA_intronic
CAediting_915242	chr12_95488394_+	ncRNA_intronic
CAediting_915243	chr12_95488415_+	ncRNA_intronic
CAediting_915244	chr12_95488429_+	ncRNA_intronic
CAediting_915245	chr12_95488432_+	ncRNA_intronic
CAediting_915246	chr12_95488459_+	ncRNA_intronic
CAediting_915247	chr12_95490153_+	ncRNA_intronic
CAediting_915248	chr12_95490259_+	ncRNA_intronic
CAediting_915249	chr12_95492635_+	ncRNA_intronic
CAediting_915250	chr12_95492695_+	ncRNA_intronic
CAediting_915251	chr12_95493221_+	ncRNA_intronic
CAediting_915252	chr12_95493361_+	ncRNA_intronic
CAediting_915253	chr12_95493401_+	ncRNA_intronic
CAediting_915254	chr12_95493404_+	ncRNA_intronic
CAediting_915255	chr12_95498756_+	intronic
CAediting_915256	chr12_95498758_+	intronic
CAediting_915257	chr12_95498807_+	intronic
CAediting_915258	chr12_95498828_+	intronic
CAediting_915259	chr12_95498835_+	intronic
CAediting_915260	chr12_95498961_+	intronic
CAediting_915261	chr12_95498968_+	intronic
CAediting_915262	chr12_95499245_+	intronic
CAediting_915263	chr12_95499323_+	intronic
CAediting_915264	chr12_95499338_+	intronic
CAediting_915265	chr12_95499393_+	intronic
CAediting_915266	chr12_95501037_+	intronic
CAediting_915267	chr12_95501081_+	intronic
CAediting_915268	chr12_95501159_+	intronic
CAediting_915269	chr12_95501568_+	intronic
CAediting_915270	chr12_95501572_+	intronic
CAediting_915271	chr12_95501600_+	intronic
CAediting_915272	chr12_95501608_+	intronic
CAediting_915273	chr12_95505919_+	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_915142	chr12_95476245_+	SINE	Alu	AluSx
CAediting_915143	chr12_95476251_+	SINE	Alu	AluSx
CAediting_915144	chr12_95476257_+	SINE	Alu	AluSx
CAediting_915145	chr12_95476287_+	SINE	Alu	AluSx
CAediting_915146	chr12_95476291_+	SINE	Alu	AluSx
CAediting_915147	chr12_95476292_+	SINE	Alu	AluSx
CAediting_915148	chr12_95476321_+	SINE	Alu	AluSx
CAediting_915149	chr12_95476331_+	SINE	Alu	AluSx
CAediting_915150	chr12_95476336_+	SINE	Alu	AluSx
CAediting_915151	chr12_95476391_+	SINE	Alu	AluSx
CAediting_915152	chr12_95476392_+	SINE	Alu	AluSx
CAediting_915153	chr12_95476397_+	SINE	Alu	AluSx
CAediting_915154	chr12_95476398_+	SINE	Alu	AluSx
CAediting_915155	chr12_95476400_+	SINE	Alu	AluSx
CAediting_915156	chr12_95476401_+	SINE	Alu	AluSx
CAediting_915157	chr12_95476408_+	SINE	Alu	AluSx
CAediting_915158	chr12_95476409_+	SINE	Alu	AluSx
CAediting_915159	chr12_95476414_+	SINE	Alu	AluSx
CAediting_915160	chr12_95476457_+	SINE	Alu	AluSx
CAediting_915161	chr12_95476462_+	SINE	Alu	AluSx
CAediting_915162	chr12_95476464_+	SINE	Alu	AluSx
CAediting_915163	chr12_95476469_+	SINE	Alu	AluSx
CAediting_915164	chr12_95477154_+	SINE	Alu	AluSx1
CAediting_915165	chr12_95477197_+	SINE	Alu	AluSx1
CAediting_915166	chr12_95477227_+	SINE	Alu	AluSx1
CAediting_915167	chr12_95477263_+	SINE	Alu	AluSx1
CAediting_915168	chr12_95478353_+	SINE	Alu	AluSq2
CAediting_915169	chr12_95478362_+	SINE	Alu	AluSq2
CAediting_915170	chr12_95478376_+	SINE	Alu	AluSq2
CAediting_915171	chr12_95478611_+	SINE	Alu	AluSq2
CAediting_915172	chr12_95481155_+	SINE	Alu	AluJr
CAediting_915173	chr12_95481175_+	SINE	Alu	AluJr
CAediting_915174	chr12_95481177_+	SINE	Alu	AluJr
CAediting_915175	chr12_95481178_+	SINE	Alu	AluJr
CAediting_915176	chr12_95481264_+	SINE	Alu	AluJr
CAediting_915177	chr12_95481268_+	SINE	Alu	AluJr
CAediting_915178	chr12_95481304_+	SINE	Alu	AluJr
CAediting_915179	chr12_95481331_+	SINE	Alu	AluJr
CAediting_915180	chr12_95481339_+	SINE	Alu	AluJr
CAediting_915181	chr12_95482189_+	SINE	Alu	AluJb
CAediting_915182	chr12_95482209_+	SINE	Alu	AluJb
CAediting_915183	chr12_95482237_+	SINE	Alu	AluJb
CAediting_915184	chr12_95482241_+	SINE	Alu	AluJb
CAediting_915185	chr12_95482259_+	SINE	Alu	AluJb
CAediting_915186	chr12_95482261_+	SINE	Alu	AluJb
CAediting_915187	chr12_95482302_+	SINE	Alu	AluJb
CAediting_915188	chr12_95482310_+	SINE	Alu	AluJb
CAediting_915189	chr12_95482333_+	SINE	Alu	AluJb
CAediting_915190	chr12_95482348_+	SINE	Alu	AluJb
CAediting_915191	chr12_95482365_+	SINE	Alu	AluJb
CAediting_915192	chr12_95482387_+	SINE	Alu	AluJb
CAediting_915193	chr12_95482524_+	SINE	Alu	AluSz6
CAediting_915194	chr12_95482525_+	SINE	Alu	AluSz6
CAediting_915195	chr12_95482530_+	SINE	Alu	AluSz6
CAediting_915196	chr12_95482545_+	SINE	Alu	AluSz6
CAediting_915197	chr12_95482546_+	SINE	Alu	AluSz6
CAediting_915198	chr12_95482554_+	SINE	Alu	AluSz6
CAediting_915199	chr12_95482555_+	SINE	Alu	AluSz6
CAediting_915200	chr12_95482559_+	SINE	Alu	AluSz6
CAediting_915201	chr12_95482578_+	SINE	Alu	AluSz6
CAediting_915202	chr12_95482592_+	SINE	Alu	AluSz6
CAediting_915203	chr12_95482593_+	SINE	Alu	AluSz6
CAediting_915204	chr12_95482634_+	SINE	Alu	AluSz6
CAediting_915205	chr12_95482635_+	SINE	Alu	AluSz6
CAediting_915206	chr12_95482636_+	SINE	Alu	AluSz6
CAediting_915207	chr12_95482655_+	SINE	Alu	AluSz6
CAediting_915208	chr12_95482659_+	SINE	Alu	AluSz6
CAediting_915209	chr12_95482666_+	SINE	Alu	AluSz6
CAediting_915210	chr12_95482711_+	SINE	Alu	AluSz6
CAediting_915211	chr12_95482713_+	SINE	Alu	AluSz6
CAediting_915212	chr12_95482780_+	SINE	Alu	AluSz6
CAediting_915213	chr12_95482932_+	SINE	Alu	FLAM_A
CAediting_915214	chr12_95482984_+	SINE	Alu	FLAM_A
CAediting_915215	chr12_95483010_+	SINE	Alu	FLAM_A
CAediting_915216	chr12_95483382_+	SINE	Alu	AluSx
CAediting_915217	chr12_95483401_+	SINE	Alu	AluSx
CAediting_915218	chr12_95483402_+	SINE	Alu	AluSx
CAediting_915219	chr12_95483412_+	SINE	Alu	AluSx
CAediting_915220	chr12_95483420_+	SINE	Alu	AluSx
CAediting_915221	chr12_95483421_+	SINE	Alu	AluSx
CAediting_915222	chr12_95483426_+	SINE	Alu	AluSx
CAediting_915223	chr12_95486597_+	SINE	Alu	AluSp
CAediting_915224	chr12_95486598_+	SINE	Alu	AluSp
CAediting_915225	chr12_95486627_+	SINE	Alu	AluSp
CAediting_915226	chr12_95486637_+	SINE	Alu	AluSp
CAediting_915227	chr12_95486680_+	SINE	Alu	AluSp
CAediting_915228	chr12_95486725_+	SINE	Alu	AluSp
CAediting_915229	chr12_95486731_+	SINE	Alu	AluSp
CAediting_915230	chr12_95486758_+	SINE	Alu	AluSp
CAediting_915231	chr12_95486759_+	SINE	Alu	AluSp
CAediting_915232	chr12_95488222_+	SINE	Alu	AluSx
CAediting_915233	chr12_95488271_+	SINE	Alu	AluSx
CAediting_915234	chr12_95488285_+	SINE	Alu	AluSx
CAediting_915235	chr12_95488290_+	SINE	Alu	AluSx
CAediting_915236	chr12_95488299_+	SINE	Alu	AluSx
CAediting_915237	chr12_95488314_+	SINE	Alu	AluSx
CAediting_915238	chr12_95488322_+	SINE	Alu	AluSx
CAediting_915239	chr12_95488362_+	SINE	Alu	AluSx
CAediting_915240	chr12_95488388_+	SINE	Alu	AluSx
CAediting_915241	chr12_95488389_+	SINE	Alu	AluSx
CAediting_915242	chr12_95488394_+	SINE	Alu	AluSx
CAediting_915243	chr12_95488415_+	SINE	Alu	AluSx
CAediting_915244	chr12_95488429_+	SINE	Alu	AluSx
CAediting_915245	chr12_95488432_+	SINE	Alu	AluSx
CAediting_915246	chr12_95488459_+	SINE	Alu	AluSx
CAediting_915247	chr12_95490153_+	SINE	Alu	AluJo
CAediting_915248	chr12_95490259_+	SINE	Alu	AluJo
CAediting_915249	chr12_95492635_+	SINE	Alu	AluJr4
CAediting_915250	chr12_95492695_+	SINE	Alu	AluJr4
CAediting_915251	chr12_95493221_+	SINE	Alu	AluJr
CAediting_915252	chr12_95493361_+	SINE	Alu	AluJr
CAediting_915253	chr12_95493401_+	SINE	Alu	AluJr
CAediting_915254	chr12_95493404_+	SINE	Alu	AluJr
CAediting_915255	chr12_95498756_+	SINE	Alu	AluJr
CAediting_915256	chr12_95498758_+	SINE	Alu	AluJr
CAediting_915257	chr12_95498807_+	SINE	Alu	AluJr
CAediting_915258	chr12_95498828_+	SINE	Alu	AluJr
CAediting_915259	chr12_95498835_+	SINE	Alu	AluJr
CAediting_915260	chr12_95498961_+	SINE	Alu	AluJr
CAediting_915261	chr12_95498968_+	SINE	Alu	AluJr
CAediting_915262	chr12_95499245_+	SINE	Alu	AluJr
CAediting_915263	chr12_95499323_+	SINE	Alu	AluJr
CAediting_915264	chr12_95499338_+	SINE	Alu	AluJr
CAediting_915265	chr12_95499393_+	SINE	Alu	AluJr
CAediting_915266	chr12_95501037_+	SINE	Alu	AluJr
CAediting_915267	chr12_95501081_+	SINE	Alu	AluJr
CAediting_915268	chr12_95501159_+	SINE	Alu	AluJr
CAediting_915269	chr12_95501568_+	SINE	Alu	AluSc
CAediting_915270	chr12_95501572_+	SINE	Alu	AluSc
CAediting_915271	chr12_95501600_+	SINE	Alu	AluSc
CAediting_915272	chr12_95501608_+	SINE	Alu	AluSc
CAediting_915273	chr12_95505919_+	SINE	Alu	AluSx

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RNA A-to-I editing events in the alternative splicing sites for METAP2

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
ES	CAediting_915182	chr12_95482209_+	95482208:95482216	5SS	2+0i	CAGGTGATC	4.28	CGGGTGATC	1.21

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000111142.12.METAP2.

Correlation between RNA A-to-I editing and PSI for ENSG00000111142.12.METAP2.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for METAP2

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for METAP2

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for METAP2

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_393	chr1_1167164_+	ENSG00000111142.12	ENST00000323666	hsa-miR-200b-3p	95515248	95515255	8mer-1a	95515234	95515255	140	-10.61
CAediting_1160181	chr17_7017644_-	ENSG00000111142.12	ENST00000323666	hsa-miR-195-3p	95514630	95514636	7mer-m8	95514619	95514637	141	-9.31
CAediting_1351755	chr19_40282625_-	ENSG00000111142.12	ENST00000323666	hsa-miR-641	95515356	95515362	7mer-m8	95515339	95515363	153	-12.93

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_604450	chr7_133034877_-	ENSG00000111142.12	ENST00000323666	hsa-miR-3654	95514687	95514693	7mer-m8	95514676	95514694	151	-17.38

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for METAP2

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for METAP2

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for METAP2

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for METAP2

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for METAP2

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
METAP2	P50579	DB02893	D-Methionine	Methionine aminopeptidase 2	SmallMoleculeDrug	approved\|experimental\|investigational
METAP2	P50579	DB00134	Methionine	Methionine aminopeptidase 2	SmallMoleculeDrug	approved\|nutraceutical

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RelatedDiseases for METAP2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene