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Editing gene: WDR4 (CAeditome ID:10785)

Gene summary for WDR4

Gene summary

Gene information	Gene symbol	WDR4
	Gene ID	10785
	Gene name	WD repeat domain 4
	Synonyms	GAMOS6\|MIGSB\|TRM82\|TRMT82\|Wuho\|hWH
	Cytomap	21q22.3
	Type of gene	protein-coding
	Description	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4TRM82 tRNA methyltransferase 82 homologWD repeat-containing protein 4protein Wuho homologtRNA (guanine-N(7)-)-methyltransferase subunit WDR4
	Modification date	20210518
	UniProtAcc	P57081
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
WDR4	GO:0008176	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4	12403464
WDR4	GO:0006400	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4	15861136
WDR4	GO:0005634	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4	15861136
WDR4	GO:0005654	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4	0000052
WDR4	GO:0005829	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4	0000052
WDR4	GO:0043527	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4	12403464

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RNA A-to-I events for WDR4

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000160193.10

RNA A-to-I editing events in Cancer.

CAediting_1454305(42843424, -), CAediting_1454306(42843425, -), CAediting_1454307(42843426, -), CAediting_1454308(42843427, -), CAediting_1454309(42843428, -), CAediting_1454310(42843430, -), CAediting_1454311(42843431, -), CAediting_1454312(42843432, -), CAediting_1454313(42843440, -), CAediting_1454314(42843463, -), CAediting_1454315(42843468, -), CAediting_1454316(42843471, -), CAediting_1454317(42843483, -), CAediting_1454318(42843484, -), CAediting_1454319(42843487, -), CAediting_1454320(42843494, -), CAediting_1454321(42843500, -), CAediting_1454322(42843508, -), CAediting_1454323(42843513, -), CAediting_1454324(42843516, -), CAediting_1454325(42843519, -), CAediting_1454326(42843526, -), CAediting_1454327(42843532, -), CAediting_1454328(42843543, -), CAediting_1454329(42843549, -), CAediting_1454330(42843557, -), CAediting_1454331(42843559, -), CAediting_1454332(42843571, -), CAediting_1454333(42843575, -), CAediting_1454334(42843578, -), CAediting_1454335(42843579, -), CAediting_1454336(42843580, -), CAediting_1454337(42843581, -), CAediting_1454338(42843582, -), CAediting_1454339(42843583, -), CAediting_1454340(42843584, -), CAediting_1454341(42843585, -), CAediting_1454342(42843586, -), CAediting_1454343(42843587, -), CAediting_1454344(42843588, -), CAediting_1454345(42843600, -), CAediting_1454346(42843601, -), CAediting_1454347(42843603, -), CAediting_1454348(42843604, -), CAediting_1454349(42843607, -), CAediting_1454350(42843609, -), CAediting_1454351(42843621, -), CAediting_1454352(42843626, -), CAediting_1454353(42843631, -), CAediting_1454354(42843639, -), CAediting_1454355(42843641, -), CAediting_1454356(42843646, -), CAediting_1454357(42843663, -), CAediting_1454358(42843670, -), CAediting_1454359(42843671, -), CAediting_1454360(42843679, -), CAediting_1454361(42843680, -), CAediting_1454362(42843682, -), CAediting_1454363(42843685, -), CAediting_1454364(42843688, -), CAediting_1454365(42843689, -), CAediting_1454366(42843697, -), CAediting_1454367(42843702, -), CAediting_1454368(42843706, -), CAediting_1454369(42843720, -), CAediting_1454370(42843730, -), CAediting_1454371(42843733, -), CAediting_1454372(42843734, -), CAediting_1454373(42843735, -), CAediting_1454374(42843736, -), CAediting_1454375(42843737, -), CAediting_1454376(42843740, -), CAediting_1454377(42843742, -), CAediting_1454378(42843744, -), CAediting_1454379(42843745, -), CAediting_1454380(42843746, -), CAediting_1454381(42843761, -), CAediting_1454382(42843762, -), CAediting_1454383(42843768, -), CAediting_1454384(42843770, -), CAediting_1454385(42843771, -), CAediting_1454386(42843780, -), CAediting_1454387(42843783, -), CAediting_1454388(42843785, -), CAediting_1454389(42843791, -), CAediting_1454390(42843794, -), CAediting_1454391(42843799, -), CAediting_1454392(42843800, -), CAediting_1454393(42843802, -), CAediting_1454394(42843823, -), CAediting_1454395(42843831, -), CAediting_1454396(42843832, -), CAediting_1454397(42843840, -), CAediting_1454398(42843860, -), CAediting_1454399(42843867, -), CAediting_1454400(42843869, -), CAediting_1454401(42843870, -), CAediting_1454402(42843871, -), CAediting_1454403(42843872, -), CAediting_1454404(42843890, -), CAediting_1454405(42843894, -), CAediting_1454406(42843895, -), CAediting_1454407(42843907, -), CAediting_1454408(42843909, -), CAediting_1454409(42843923, -), CAediting_1454410(42843931, -), CAediting_1454411(42843941, -), CAediting_1454412(42843947, -), CAediting_1454413(42843955, -), CAediting_1454414(42843958, -), CAediting_1454415(42843970, -), CAediting_1454416(42843972, -), CAediting_1454417(42845003, -), CAediting_1454418(42845874, -), CAediting_1454419(42845876, -), CAediting_1454420(42845888, -), CAediting_1454421(42845889, -), CAediting_1454422(42845890, -), CAediting_1454423(42845898, -), CAediting_1454424(42845912, -), CAediting_1454425(42845915, -), CAediting_1454426(42845916, -), CAediting_1454427(42845929, -), CAediting_1454428(42845967, -), CAediting_1454429(42845985, -), CAediting_1454430(42846008, -), CAediting_1454431(42846020, -), CAediting_1454432(42846032, -), CAediting_1454433(42846037, -), CAediting_1454434(42846049, -), CAediting_1454435(42846050, -), CAediting_1454436(42846087, -), CAediting_1454437(42846092, -), CAediting_1454438(42846099, -), CAediting_1454439(42846103, -), CAediting_1454440(42846119, -), CAediting_1454441(42846125, -), CAediting_1454442(42846131, -), CAediting_1454443(42846582, -), CAediting_1454444(42846591, -), CAediting_1454445(42846603, -), CAediting_1454446(42846618, -), CAediting_1454447(42846627, -), CAediting_1454448(42846630, -), CAediting_1454449(42846631, -), CAediting_1454450(42846637, -), CAediting_1454451(42846644, -), CAediting_1454452(42846651, -), CAediting_1454453(42846656, -), CAediting_1454454(42846661, -), CAediting_1454455(42846666, -), CAediting_1454456(42846680, -), CAediting_1454457(42846681, -), CAediting_1454458(42846691, -), CAediting_1454459(42846709, -), CAediting_1454460(42846763, -), CAediting_1454461(42846777, -), CAediting_1454462(42846817, -), CAediting_1454463(42846830, -), CAediting_1454464(42846839, -), CAediting_1454465(42846854, -), CAediting_1454466(42846856, -), CAediting_1454467(42846859, -), CAediting_1454468(42846873, -), CAediting_1454469(42846874, -), CAediting_1454470(42846884, -), CAediting_1454471(42846887, -), CAediting_1454472(42846900, -), CAediting_1454473(42846921, -), CAediting_1454474(42846926, -), CAediting_1454475(42846934, -), CAediting_1454476(42846938, -), CAediting_1454477(42846939, -), CAediting_1454478(42846959, -), CAediting_1454479(42846976, -), CAediting_1454480(42846981, -), CAediting_1454481(42846992, -), CAediting_1454482(42846994, -), CAediting_1454483(42847005, -), CAediting_1454484(42847012, -), CAediting_1454485(42847032, -), CAediting_1454486(42847036, -), CAediting_1454487(42867810, -), CAediting_1454488(42872375, -), CAediting_1454489(42872438, -), CAediting_1454490(42872499, -), CAediting_1454491(42872675, -), CAediting_1454492(42872890, -), CAediting_1454493(42876351, -), CAediting_1454494(42876983, -), CAediting_1454495(42877236, -), CAediting_1454496(42877249, -), CAediting_1454497(42877272, -), CAediting_1454498(42877276, -), CAediting_1454499(42877281, -), CAediting_1454500(42877292, -), CAediting_1454501(42877308, -), CAediting_1454502(42877311, -), CAediting_1454503(42877315, -), CAediting_1454504(42877347, -), CAediting_1454505(42877348, -), CAediting_1454506(42877357, -), CAediting_1454507(42877386, -),

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RNA editing positional annotations for WDR4 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1454305	chr21_42843424_-	intronic
CAediting_1454306	chr21_42843425_-	intronic
CAediting_1454307	chr21_42843426_-	intronic
CAediting_1454308	chr21_42843427_-	intronic
CAediting_1454309	chr21_42843428_-	intronic
CAediting_1454310	chr21_42843430_-	intronic
CAediting_1454311	chr21_42843431_-	intronic
CAediting_1454312	chr21_42843432_-	intronic
CAediting_1454313	chr21_42843440_-	intronic
CAediting_1454314	chr21_42843463_-	intronic
CAediting_1454315	chr21_42843468_-	intronic
CAediting_1454316	chr21_42843471_-	intronic
CAediting_1454317	chr21_42843483_-	intronic
CAediting_1454318	chr21_42843484_-	intronic
CAediting_1454319	chr21_42843487_-	intronic
CAediting_1454320	chr21_42843494_-	intronic
CAediting_1454321	chr21_42843500_-	intronic
CAediting_1454322	chr21_42843508_-	intronic
CAediting_1454323	chr21_42843513_-	intronic
CAediting_1454324	chr21_42843516_-	intronic
CAediting_1454325	chr21_42843519_-	intronic
CAediting_1454326	chr21_42843526_-	intronic
CAediting_1454327	chr21_42843532_-	intronic
CAediting_1454328	chr21_42843543_-	intronic
CAediting_1454329	chr21_42843549_-	intronic
CAediting_1454330	chr21_42843557_-	intronic
CAediting_1454331	chr21_42843559_-	intronic
CAediting_1454332	chr21_42843571_-	intronic
CAediting_1454333	chr21_42843575_-	intronic
CAediting_1454334	chr21_42843578_-	intronic
CAediting_1454335	chr21_42843579_-	intronic
CAediting_1454336	chr21_42843580_-	intronic
CAediting_1454337	chr21_42843581_-	intronic
CAediting_1454338	chr21_42843582_-	intronic
CAediting_1454339	chr21_42843583_-	intronic
CAediting_1454340	chr21_42843584_-	intronic
CAediting_1454341	chr21_42843585_-	intronic
CAediting_1454342	chr21_42843586_-	intronic
CAediting_1454343	chr21_42843587_-	intronic
CAediting_1454344	chr21_42843588_-	intronic
CAediting_1454345	chr21_42843600_-	intronic
CAediting_1454346	chr21_42843601_-	intronic
CAediting_1454347	chr21_42843603_-	intronic
CAediting_1454348	chr21_42843604_-	intronic
CAediting_1454349	chr21_42843607_-	intronic
CAediting_1454350	chr21_42843609_-	intronic
CAediting_1454351	chr21_42843621_-	intronic
CAediting_1454352	chr21_42843626_-	intronic
CAediting_1454353	chr21_42843631_-	intronic
CAediting_1454354	chr21_42843639_-	intronic
CAediting_1454355	chr21_42843641_-	intronic
CAediting_1454356	chr21_42843646_-	intronic
CAediting_1454357	chr21_42843663_-	intronic
CAediting_1454358	chr21_42843670_-	intronic
CAediting_1454359	chr21_42843671_-	intronic
CAediting_1454360	chr21_42843679_-	intronic
CAediting_1454361	chr21_42843680_-	intronic
CAediting_1454362	chr21_42843682_-	intronic
CAediting_1454363	chr21_42843685_-	intronic
CAediting_1454364	chr21_42843688_-	intronic
CAediting_1454365	chr21_42843689_-	intronic
CAediting_1454366	chr21_42843697_-	intronic
CAediting_1454367	chr21_42843702_-	intronic
CAediting_1454368	chr21_42843706_-	intronic
CAediting_1454369	chr21_42843720_-	intronic
CAediting_1454370	chr21_42843730_-	intronic
CAediting_1454371	chr21_42843733_-	intronic
CAediting_1454372	chr21_42843734_-	intronic
CAediting_1454373	chr21_42843735_-	intronic
CAediting_1454374	chr21_42843736_-	intronic
CAediting_1454375	chr21_42843737_-	intronic
CAediting_1454376	chr21_42843740_-	intronic
CAediting_1454377	chr21_42843742_-	intronic
CAediting_1454378	chr21_42843744_-	intronic
CAediting_1454379	chr21_42843745_-	intronic
CAediting_1454380	chr21_42843746_-	intronic
CAediting_1454381	chr21_42843761_-	intronic
CAediting_1454382	chr21_42843762_-	intronic
CAediting_1454383	chr21_42843768_-	intronic
CAediting_1454384	chr21_42843770_-	intronic
CAediting_1454385	chr21_42843771_-	intronic
CAediting_1454386	chr21_42843780_-	intronic
CAediting_1454387	chr21_42843783_-	intronic
CAediting_1454388	chr21_42843785_-	intronic
CAediting_1454389	chr21_42843791_-	intronic
CAediting_1454390	chr21_42843794_-	intronic
CAediting_1454391	chr21_42843799_-	intronic
CAediting_1454392	chr21_42843800_-	intronic
CAediting_1454393	chr21_42843802_-	intronic
CAediting_1454394	chr21_42843823_-	intronic
CAediting_1454395	chr21_42843831_-	intronic
CAediting_1454396	chr21_42843832_-	intronic
CAediting_1454397	chr21_42843840_-	intronic
CAediting_1454398	chr21_42843860_-	intronic
CAediting_1454399	chr21_42843867_-	intronic
CAediting_1454400	chr21_42843869_-	intronic
CAediting_1454401	chr21_42843870_-	intronic
CAediting_1454402	chr21_42843871_-	intronic
CAediting_1454403	chr21_42843872_-	intronic
CAediting_1454404	chr21_42843890_-	intronic
CAediting_1454405	chr21_42843894_-	intronic
CAediting_1454406	chr21_42843895_-	intronic
CAediting_1454407	chr21_42843907_-	intronic
CAediting_1454408	chr21_42843909_-	intronic
CAediting_1454409	chr21_42843923_-	intronic
CAediting_1454410	chr21_42843931_-	intronic
CAediting_1454411	chr21_42843941_-	intronic
CAediting_1454412	chr21_42843947_-	intronic
CAediting_1454413	chr21_42843955_-	intronic
CAediting_1454414	chr21_42843958_-	intronic
CAediting_1454415	chr21_42843970_-	intronic
CAediting_1454416	chr21_42843972_-	intronic
CAediting_1454417	chr21_42845003_-	intronic
CAediting_1454418	chr21_42845874_-	intronic
CAediting_1454419	chr21_42845876_-	intronic
CAediting_1454420	chr21_42845888_-	intronic
CAediting_1454421	chr21_42845889_-	intronic
CAediting_1454422	chr21_42845890_-	intronic
CAediting_1454423	chr21_42845898_-	intronic
CAediting_1454424	chr21_42845912_-	intronic
CAediting_1454425	chr21_42845915_-	intronic
CAediting_1454426	chr21_42845916_-	intronic
CAediting_1454427	chr21_42845929_-	intronic
CAediting_1454428	chr21_42845967_-	intronic
CAediting_1454429	chr21_42845985_-	intronic
CAediting_1454430	chr21_42846008_-	intronic
CAediting_1454431	chr21_42846020_-	intronic
CAediting_1454432	chr21_42846032_-	intronic
CAediting_1454433	chr21_42846037_-	intronic
CAediting_1454434	chr21_42846049_-	intronic
CAediting_1454435	chr21_42846050_-	intronic
CAediting_1454436	chr21_42846087_-	intronic
CAediting_1454437	chr21_42846092_-	intronic
CAediting_1454438	chr21_42846099_-	intronic
CAediting_1454439	chr21_42846103_-	intronic
CAediting_1454440	chr21_42846119_-	intronic
CAediting_1454441	chr21_42846125_-	intronic
CAediting_1454442	chr21_42846131_-	intronic
CAediting_1454443	chr21_42846582_-	intronic
CAediting_1454444	chr21_42846591_-	intronic
CAediting_1454445	chr21_42846603_-	intronic
CAediting_1454446	chr21_42846618_-	intronic
CAediting_1454447	chr21_42846627_-	intronic
CAediting_1454448	chr21_42846630_-	intronic
CAediting_1454449	chr21_42846631_-	intronic
CAediting_1454450	chr21_42846637_-	intronic
CAediting_1454451	chr21_42846644_-	intronic
CAediting_1454452	chr21_42846651_-	intronic
CAediting_1454453	chr21_42846656_-	intronic
CAediting_1454454	chr21_42846661_-	intronic
CAediting_1454455	chr21_42846666_-	intronic
CAediting_1454456	chr21_42846680_-	intronic
CAediting_1454457	chr21_42846681_-	intronic
CAediting_1454458	chr21_42846691_-	intronic
CAediting_1454459	chr21_42846709_-	intronic
CAediting_1454460	chr21_42846763_-	intronic
CAediting_1454461	chr21_42846777_-	intronic
CAediting_1454462	chr21_42846817_-	intronic
CAediting_1454463	chr21_42846830_-	intronic
CAediting_1454464	chr21_42846839_-	intronic
CAediting_1454465	chr21_42846854_-	intronic
CAediting_1454466	chr21_42846856_-	intronic
CAediting_1454467	chr21_42846859_-	intronic
CAediting_1454468	chr21_42846873_-	intronic
CAediting_1454469	chr21_42846874_-	intronic
CAediting_1454470	chr21_42846884_-	intronic
CAediting_1454471	chr21_42846887_-	intronic
CAediting_1454472	chr21_42846900_-	intronic
CAediting_1454473	chr21_42846921_-	intronic
CAediting_1454474	chr21_42846926_-	intronic
CAediting_1454475	chr21_42846934_-	intronic
CAediting_1454476	chr21_42846938_-	intronic
CAediting_1454477	chr21_42846939_-	intronic
CAediting_1454478	chr21_42846959_-	intronic
CAediting_1454479	chr21_42846976_-	intronic
CAediting_1454480	chr21_42846981_-	intronic
CAediting_1454481	chr21_42846992_-	intronic
CAediting_1454482	chr21_42846994_-	intronic
CAediting_1454483	chr21_42847005_-	intronic
CAediting_1454484	chr21_42847012_-	intronic
CAediting_1454485	chr21_42847032_-	intronic
CAediting_1454486	chr21_42847036_-	intronic
CAediting_1454487	chr21_42867810_-	ncRNA_intronic
CAediting_1454488	chr21_42872375_-	ncRNA_intronic
CAediting_1454489	chr21_42872438_-	ncRNA_intronic
CAediting_1454490	chr21_42872499_-	ncRNA_intronic
CAediting_1454491	chr21_42872675_-	ncRNA_intronic
CAediting_1454492	chr21_42872890_-	ncRNA_intronic
CAediting_1454493	chr21_42876351_-	ncRNA_intronic
CAediting_1454494	chr21_42876983_-	ncRNA_intronic
CAediting_1454495	chr21_42877236_-	ncRNA_intronic
CAediting_1454496	chr21_42877249_-	ncRNA_intronic
CAediting_1454497	chr21_42877272_-	ncRNA_intronic
CAediting_1454498	chr21_42877276_-	ncRNA_intronic
CAediting_1454499	chr21_42877281_-	ncRNA_intronic
CAediting_1454500	chr21_42877292_-	ncRNA_intronic
CAediting_1454501	chr21_42877308_-	ncRNA_intronic
CAediting_1454502	chr21_42877311_-	ncRNA_intronic
CAediting_1454503	chr21_42877315_-	ncRNA_intronic
CAediting_1454504	chr21_42877347_-	ncRNA_intronic
CAediting_1454505	chr21_42877348_-	ncRNA_intronic
CAediting_1454506	chr21_42877357_-	ncRNA_intronic
CAediting_1454507	chr21_42877386_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1454305	chr21_42843424_-	Simple_repeat	Simple_repeat	(T)n
CAediting_1454306	chr21_42843425_-	Simple_repeat	Simple_repeat	(T)n
CAediting_1454307	chr21_42843426_-	Simple_repeat	Simple_repeat	(T)n
CAediting_1454308	chr21_42843427_-	Simple_repeat	Simple_repeat	(T)n
CAediting_1454309	chr21_42843428_-	Simple_repeat	Simple_repeat	(T)n
CAediting_1454310	chr21_42843430_-	Simple_repeat	Simple_repeat	(T)n
CAediting_1454311	chr21_42843431_-	Simple_repeat	Simple_repeat	(T)n
CAediting_1454312	chr21_42843432_-	Simple_repeat	Simple_repeat	(T)n
CAediting_1454313	chr21_42843440_-	SINE	Alu	AluJr
CAediting_1454314	chr21_42843463_-	SINE	Alu	AluJr
CAediting_1454315	chr21_42843468_-	SINE	Alu	AluJr
CAediting_1454316	chr21_42843471_-	SINE	Alu	AluJr
CAediting_1454317	chr21_42843483_-	SINE	Alu	AluJr
CAediting_1454318	chr21_42843484_-	SINE	Alu	AluJr
CAediting_1454319	chr21_42843487_-	SINE	Alu	AluJr
CAediting_1454320	chr21_42843494_-	SINE	Alu	AluJr
CAediting_1454321	chr21_42843500_-	SINE	Alu	AluJr
CAediting_1454322	chr21_42843508_-	SINE	Alu	AluJr
CAediting_1454323	chr21_42843513_-	SINE	Alu	AluJr
CAediting_1454324	chr21_42843516_-	SINE	Alu	AluJr
CAediting_1454325	chr21_42843519_-	SINE	Alu	AluJr
CAediting_1454326	chr21_42843526_-	SINE	Alu	AluJr
CAediting_1454327	chr21_42843532_-	SINE	Alu	AluJr
CAediting_1454328	chr21_42843543_-	SINE	Alu	AluJr
CAediting_1454329	chr21_42843549_-	SINE	Alu	AluJr
CAediting_1454330	chr21_42843557_-	SINE	Alu	AluJr
CAediting_1454331	chr21_42843559_-	SINE	Alu	AluJr
CAediting_1454332	chr21_42843571_-	SINE	Alu	AluJr
CAediting_1454333	chr21_42843575_-	SINE	Alu	AluJr
CAediting_1454334	chr21_42843578_-	SINE	Alu	AluSx3
CAediting_1454335	chr21_42843579_-	SINE	Alu	AluSx3
CAediting_1454336	chr21_42843580_-	SINE	Alu	AluSx3
CAediting_1454337	chr21_42843581_-	SINE	Alu	AluSx3
CAediting_1454338	chr21_42843582_-	SINE	Alu	AluSx3
CAediting_1454339	chr21_42843583_-	SINE	Alu	AluSx3
CAediting_1454340	chr21_42843584_-	SINE	Alu	AluSx3
CAediting_1454341	chr21_42843585_-	SINE	Alu	AluSx3
CAediting_1454342	chr21_42843586_-	SINE	Alu	AluSx3
CAediting_1454343	chr21_42843587_-	SINE	Alu	AluSx3
CAediting_1454344	chr21_42843588_-	SINE	Alu	AluSx3
CAediting_1454345	chr21_42843600_-	SINE	Alu	AluSx3
CAediting_1454346	chr21_42843601_-	SINE	Alu	AluSx3
CAediting_1454347	chr21_42843603_-	SINE	Alu	AluSx3
CAediting_1454348	chr21_42843604_-	SINE	Alu	AluSx3
CAediting_1454349	chr21_42843607_-	SINE	Alu	AluSx3
CAediting_1454350	chr21_42843609_-	SINE	Alu	AluSx3
CAediting_1454351	chr21_42843621_-	SINE	Alu	AluSx3
CAediting_1454352	chr21_42843626_-	SINE	Alu	AluSx3
CAediting_1454353	chr21_42843631_-	SINE	Alu	AluSx3
CAediting_1454354	chr21_42843639_-	SINE	Alu	AluSx3
CAediting_1454355	chr21_42843641_-	SINE	Alu	AluSx3
CAediting_1454356	chr21_42843646_-	SINE	Alu	AluSx3
CAediting_1454357	chr21_42843663_-	SINE	Alu	AluSx3
CAediting_1454358	chr21_42843670_-	SINE	Alu	AluSx3
CAediting_1454359	chr21_42843671_-	SINE	Alu	AluSx3
CAediting_1454360	chr21_42843679_-	SINE	Alu	AluSx3
CAediting_1454361	chr21_42843680_-	SINE	Alu	AluSx3
CAediting_1454362	chr21_42843682_-	SINE	Alu	AluSx3
CAediting_1454363	chr21_42843685_-	SINE	Alu	AluSx3
CAediting_1454364	chr21_42843688_-	SINE	Alu	AluSx3
CAediting_1454365	chr21_42843689_-	SINE	Alu	AluSx3
CAediting_1454366	chr21_42843697_-	SINE	Alu	AluSx3
CAediting_1454367	chr21_42843702_-	SINE	Alu	AluSx3
CAediting_1454368	chr21_42843706_-	SINE	Alu	AluSx3
CAediting_1454369	chr21_42843720_-	SINE	Alu	AluSx3
CAediting_1454370	chr21_42843730_-	SINE	Alu	AluSx3
CAediting_1454371	chr21_42843733_-	SINE	Alu	AluSx3
CAediting_1454372	chr21_42843734_-	SINE	Alu	AluSx3
CAediting_1454373	chr21_42843735_-	SINE	Alu	AluSx3
CAediting_1454374	chr21_42843736_-	SINE	Alu	AluSx3
CAediting_1454375	chr21_42843737_-	SINE	Alu	AluSx3
CAediting_1454376	chr21_42843740_-	SINE	Alu	AluSx3
CAediting_1454377	chr21_42843742_-	SINE	Alu	AluSx3
CAediting_1454378	chr21_42843744_-	SINE	Alu	AluSx3
CAediting_1454379	chr21_42843745_-	SINE	Alu	AluSx3
CAediting_1454380	chr21_42843746_-	SINE	Alu	AluSx3
CAediting_1454381	chr21_42843761_-	SINE	Alu	AluSx3
CAediting_1454382	chr21_42843762_-	SINE	Alu	AluSx3
CAediting_1454383	chr21_42843768_-	SINE	Alu	AluSx3
CAediting_1454384	chr21_42843770_-	SINE	Alu	AluSx3
CAediting_1454385	chr21_42843771_-	SINE	Alu	AluSx3
CAediting_1454386	chr21_42843780_-	SINE	Alu	AluSx3
CAediting_1454387	chr21_42843783_-	SINE	Alu	AluSx3
CAediting_1454388	chr21_42843785_-	SINE	Alu	AluSx3
CAediting_1454389	chr21_42843791_-	SINE	Alu	AluSx3
CAediting_1454390	chr21_42843794_-	SINE	Alu	AluSx3
CAediting_1454391	chr21_42843799_-	SINE	Alu	AluSx3
CAediting_1454392	chr21_42843800_-	SINE	Alu	AluSx3
CAediting_1454393	chr21_42843802_-	SINE	Alu	AluSx3
CAediting_1454394	chr21_42843823_-	SINE	Alu	AluSx3
CAediting_1454395	chr21_42843831_-	SINE	Alu	AluSx3
CAediting_1454396	chr21_42843832_-	SINE	Alu	AluSx3
CAediting_1454397	chr21_42843840_-	SINE	Alu	AluSx3
CAediting_1454398	chr21_42843860_-	SINE	Alu	AluJr
CAediting_1454399	chr21_42843867_-	SINE	Alu	AluJr
CAediting_1454400	chr21_42843869_-	SINE	Alu	AluJr
CAediting_1454401	chr21_42843870_-	SINE	Alu	AluJr
CAediting_1454402	chr21_42843871_-	SINE	Alu	AluJr
CAediting_1454403	chr21_42843872_-	SINE	Alu	AluJr
CAediting_1454404	chr21_42843890_-	SINE	Alu	AluJr
CAediting_1454405	chr21_42843894_-	SINE	Alu	AluJr
CAediting_1454406	chr21_42843895_-	SINE	Alu	AluJr
CAediting_1454407	chr21_42843907_-	SINE	Alu	AluJr
CAediting_1454408	chr21_42843909_-	SINE	Alu	AluJr
CAediting_1454409	chr21_42843923_-	SINE	Alu	AluJr
CAediting_1454410	chr21_42843931_-	SINE	Alu	AluJr
CAediting_1454411	chr21_42843941_-	SINE	Alu	AluJr
CAediting_1454412	chr21_42843947_-	SINE	Alu	AluJr
CAediting_1454413	chr21_42843955_-	SINE	Alu	AluJr
CAediting_1454414	chr21_42843958_-	SINE	Alu	AluJr
CAediting_1454415	chr21_42843970_-	SINE	Alu	AluJr
CAediting_1454416	chr21_42843972_-	SINE	Alu	AluJr
CAediting_1454417	chr21_42845003_-	LTR	ERVL	LTR41
CAediting_1454418	chr21_42845874_-	SINE	Alu	AluJr
CAediting_1454419	chr21_42845876_-	SINE	Alu	AluJr
CAediting_1454420	chr21_42845888_-	SINE	Alu	AluJr
CAediting_1454421	chr21_42845889_-	SINE	Alu	AluJr
CAediting_1454422	chr21_42845890_-	SINE	Alu	AluJr
CAediting_1454423	chr21_42845898_-	SINE	Alu	AluJr
CAediting_1454424	chr21_42845912_-	SINE	Alu	AluJr
CAediting_1454425	chr21_42845915_-	SINE	Alu	AluJr
CAediting_1454426	chr21_42845916_-	SINE	Alu	AluJr
CAediting_1454427	chr21_42845929_-	SINE	Alu	AluJr
CAediting_1454428	chr21_42845967_-	SINE	Alu	AluJr
CAediting_1454429	chr21_42845985_-	SINE	Alu	AluJr
CAediting_1454430	chr21_42846008_-	SINE	Alu	AluJr
CAediting_1454431	chr21_42846020_-	SINE	Alu	AluJr
CAediting_1454432	chr21_42846032_-	SINE	Alu	AluJr
CAediting_1454433	chr21_42846037_-	SINE	Alu	AluJr
CAediting_1454434	chr21_42846049_-	SINE	Alu	AluJr
CAediting_1454435	chr21_42846050_-	SINE	Alu	AluJr
CAediting_1454436	chr21_42846087_-	SINE	Alu	AluJr
CAediting_1454437	chr21_42846092_-	SINE	Alu	AluJr
CAediting_1454438	chr21_42846099_-	SINE	Alu	AluJr
CAediting_1454439	chr21_42846103_-	SINE	Alu	AluJr
CAediting_1454440	chr21_42846119_-	SINE	Alu	AluJr
CAediting_1454441	chr21_42846125_-	SINE	Alu	AluJr
CAediting_1454442	chr21_42846131_-	SINE	Alu	AluJr
CAediting_1454443	chr21_42846582_-	SINE	Alu	AluJb
CAediting_1454444	chr21_42846591_-	SINE	Alu	AluJb
CAediting_1454445	chr21_42846603_-	SINE	Alu	AluJb
CAediting_1454446	chr21_42846618_-	SINE	Alu	AluJb
CAediting_1454447	chr21_42846627_-	SINE	Alu	AluJb
CAediting_1454448	chr21_42846630_-	SINE	Alu	AluJb
CAediting_1454449	chr21_42846631_-	SINE	Alu	AluJb
CAediting_1454450	chr21_42846637_-	SINE	Alu	AluJb
CAediting_1454451	chr21_42846644_-	SINE	Alu	AluJb
CAediting_1454452	chr21_42846651_-	SINE	Alu	AluJb
CAediting_1454453	chr21_42846656_-	SINE	Alu	AluJb
CAediting_1454454	chr21_42846661_-	SINE	Alu	AluJb
CAediting_1454455	chr21_42846666_-	SINE	Alu	AluJb
CAediting_1454456	chr21_42846680_-	SINE	Alu	AluJb
CAediting_1454457	chr21_42846681_-	SINE	Alu	AluJb
CAediting_1454458	chr21_42846691_-	SINE	Alu	AluJb
CAediting_1454459	chr21_42846709_-	SINE	Alu	AluJb
CAediting_1454460	chr21_42846763_-	SINE	Alu	AluSx1
CAediting_1454461	chr21_42846777_-	SINE	Alu	AluSx1
CAediting_1454462	chr21_42846817_-	SINE	Alu	AluSx1
CAediting_1454463	chr21_42846830_-	SINE	Alu	AluSx1
CAediting_1454464	chr21_42846839_-	SINE	Alu	AluSx1
CAediting_1454465	chr21_42846854_-	SINE	Alu	AluSx1
CAediting_1454466	chr21_42846856_-	SINE	Alu	AluSx1
CAediting_1454467	chr21_42846859_-	SINE	Alu	AluSx1
CAediting_1454468	chr21_42846873_-	SINE	Alu	AluSx1
CAediting_1454469	chr21_42846874_-	SINE	Alu	AluSx1
CAediting_1454470	chr21_42846884_-	SINE	Alu	AluSx1
CAediting_1454471	chr21_42846887_-	SINE	Alu	AluSx1
CAediting_1454472	chr21_42846900_-	SINE	Alu	AluSx1
CAediting_1454473	chr21_42846921_-	SINE	Alu	AluSx1
CAediting_1454474	chr21_42846926_-	SINE	Alu	AluSx1
CAediting_1454475	chr21_42846934_-	SINE	Alu	AluSx1
CAediting_1454476	chr21_42846938_-	SINE	Alu	AluSx1
CAediting_1454477	chr21_42846939_-	SINE	Alu	AluSx1
CAediting_1454478	chr21_42846959_-	SINE	Alu	AluSx1
CAediting_1454479	chr21_42846976_-	SINE	Alu	AluSx1
CAediting_1454480	chr21_42846981_-	SINE	Alu	AluSx1
CAediting_1454481	chr21_42846992_-	SINE	Alu	AluSx1
CAediting_1454482	chr21_42846994_-	SINE	Alu	AluSx1
CAediting_1454483	chr21_42847005_-	SINE	Alu	AluSx1
CAediting_1454484	chr21_42847012_-	SINE	Alu	AluSx1
CAediting_1454485	chr21_42847032_-	SINE	Alu	AluSx1
CAediting_1454486	chr21_42847036_-	SINE	Alu	AluSx1
CAediting_1454487	chr21_42867810_-	SINE	Alu	FLAM_C
CAediting_1454488	chr21_42872375_-	SINE	Alu	AluSx
CAediting_1454489	chr21_42872438_-	SINE	Alu	AluSx
CAediting_1454490	chr21_42872499_-	SINE	Alu	AluSx
CAediting_1454491	chr21_42872675_-	SINE	Alu	AluSq2
CAediting_1454492	chr21_42872890_-	SINE	Alu	AluSq2
CAediting_1454493	chr21_42876351_-	SINE	Alu	AluSx1
CAediting_1454494	chr21_42876983_-	SINE	Alu	AluSp
CAediting_1454495	chr21_42877236_-	SINE	Alu	AluSx1
CAediting_1454496	chr21_42877249_-	SINE	Alu	AluSx1
CAediting_1454497	chr21_42877272_-	SINE	Alu	AluSx1
CAediting_1454498	chr21_42877276_-	SINE	Alu	AluSx1
CAediting_1454499	chr21_42877281_-	SINE	Alu	AluSx1
CAediting_1454500	chr21_42877292_-	SINE	Alu	AluSx1
CAediting_1454501	chr21_42877308_-	SINE	Alu	AluSx1
CAediting_1454502	chr21_42877311_-	SINE	Alu	AluSx1
CAediting_1454503	chr21_42877315_-	SINE	Alu	AluSx1
CAediting_1454504	chr21_42877347_-	SINE	Alu	AluSx1
CAediting_1454505	chr21_42877348_-	SINE	Alu	AluSx1
CAediting_1454506	chr21_42877357_-	SINE	Alu	AluSx1
CAediting_1454507	chr21_42877386_-	SINE	Alu	AluSx1

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RNA A-to-I editing events in the alternative splicing sites for WDR4

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
IR	CAediting_1454459	chr21_42846709_-	42846705:42846727	3SS	0+2i	TTCTAAGCACTTTCTTCCAGACG	4.7	TTCTAAGCACTTTCTTCCGGACG	-3.26

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000160193.10.WDR4.

Correlation between RNA A-to-I editing and PSI for ENSG00000160193.10.WDR4.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for WDR4

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ESCA.CAediting_1454364.ENSG00000160193.WDR4.png
Soverview

ESCA.CAediting_1454365.ENSG00000160193.WDR4.png
Soverview

PAAD.CAediting_1454318.ENSG00000160193.WDR4.png
Soverview

STAD.CAediting_1454316.ENSG00000160193.WDR4.png
Soverview

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Protein coding region RNA A-to-I editings for WDR4

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for WDR4

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1368054	chr19_46709310_-	ENSG00000160193.10	ENST00000398208	hsa-miR-320e	42849932	42849939	8mer-1a	42849932	42849948	141	-12.92

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_396018	chr5_1062918_-	ENSG00000160193.10	ENST00000398208	hsa-miR-4635	42849964	42849971	8mer-1a	42849964	42849984	146	-14.09

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for WDR4

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for WDR4

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BLCA	CAediting_1454316	chr21_42843471_-	1.25034808612454e-06	0.297534748928466	0.0299867914987865	0.135677704372107	.	.
LGG	CAediting_1454316	chr21_42843471_-	0.00340265188866971	0.164807793295463	.	.	.	.
BRCA	CAediting_1454316	chr21_42843471_-	2.9285395013218e-05	0.157246969872559	.	.	.	.
LUAD	CAediting_1454316	chr21_42843471_-	4.07741442610358e-05	0.254943617667011	.	.	.	.
COAD	CAediting_1454316	chr21_42843471_-	1.97358566381258e-05	0.268996646266528	.	.	.	.
LUSC	CAediting_1454316	chr21_42843471_-	0.0191244699339018	0.140213313537334	.	.	.	.
GBM	CAediting_1454316	chr21_42843471_-	0.00575608921163424	0.282759123745899	.	.	.	.
PRAD	CAediting_1454316	chr21_42843471_-	0.00730293309834599	0.168289015168701	.	.	.	.
HNSC	CAediting_1454316	chr21_42843471_-	0.0196985588851474	0.135266630874426	.	.	.	.
STAD	CAediting_1454316	chr21_42843471_-	0.0303340621134795	0.143788625860226	.	.	.	.
UCEC	CAediting_1454316	chr21_42843471_-	0.0360047766914381	0.141144498215805	.	.	.	.
OV	CAediting_1454316	chr21_42843471_-	0.004000905209771	0.174939724357327	.	.	.	.
SKCM	CAediting_1454316	chr21_42843471_-	0.000473231693855678	0.187471728065345	.	.	.	.
READ	CAediting_1454316	chr21_42843471_-	0.00139743407681882	0.339231731371548	.	.	.	.
TGCT	CAediting_1454316	chr21_42843471_-	0.0111005463673353	0.217959289387832	.	.	.	.
BLCA	CAediting_1454317	chr21_42843483_-	0.0259807105237355	0.159857059044201	.	.	.	.
LGG	CAediting_1454317	chr21_42843483_-	.	.	0.0285433536804954	0.195142586531581	.	.
BRCA	CAediting_1454317	chr21_42843483_-	0.000175642346031035	0.175386475819828	.	.	.	.
CESC	CAediting_1454317	chr21_42843483_-	0.00735687607974002	0.20921445726058	.	.	.	.
COAD	CAediting_1454317	chr21_42843483_-	0.0270988472378306	0.167088335162603	.	.	.	.
LUSC	CAediting_1454317	chr21_42843483_-	0.0174023618505836	0.166360254632049	.	.	.	.
HNSC	CAediting_1454317	chr21_42843483_-	0.00149609786807887	0.227637786123624	.	.	.	.
STAD	CAediting_1454317	chr21_42843483_-	0.0217207799794079	0.169598304530024	.	.	.	.
THCA	CAediting_1454317	chr21_42843483_-	0.0114667975660866	0.183547875020517	.	.	.	.
OV	CAediting_1454317	chr21_42843483_-	0.00193775481528336	0.230169559100197	.	.	.	.
SKCM	CAediting_1454317	chr21_42843483_-	0.00279898037377841	0.209784643077311	.	.	.	.
LGG	CAediting_1454318	chr21_42843484_-	0.0394129718831485	0.137436447035817	0.00106022693341804	0.216873465632121	.	.
BRCA	CAediting_1454318	chr21_42843484_-	0.00513236100757298	0.110761026299095	.	.	.	.
CESC	CAediting_1454318	chr21_42843484_-	0.0207734847674244	0.148263575280039	.	.	.	.
LUSC	CAediting_1454318	chr21_42843484_-	0.0125173960751996	0.137128960246587	.	.	.	.
GBM	CAediting_1454318	chr21_42843484_-	.	.	.	.	0.0248849876366517	0.253911888959804
HNSC	CAediting_1454318	chr21_42843484_-	0.00147661335444953	0.181571970107192	.	.	.	.
STAD	CAediting_1454318	chr21_42843484_-	0.0425372501328594	0.13386405940982	.	.	.	.
OV	CAediting_1454318	chr21_42843484_-	0.00375336560098855	0.179487520553088	.	.	.	.
SKCM	CAediting_1454318	chr21_42843484_-	0.0014930493500139	0.17415761467232	.	.	.	.
READ	CAediting_1454318	chr21_42843484_-	0.000307369220385729	0.351930594236722	.	.	.	.
THYM	CAediting_1454318	chr21_42843484_-	0.0334122109421938	0.258341462356713	.	.	.	.
LUSC	CAediting_1454323	chr21_42843513_-	.	.	.	.	0.0149561838782093	0.305338358732838
PRAD	CAediting_1454323	chr21_42843513_-	0.0275421743682082	0.294564050510958	.	.	.	.
STAD	CAediting_1454323	chr21_42843513_-	.	.	0.0436263549629186	0.170191150979799	.	.
OV	CAediting_1454323	chr21_42843513_-	0.0335906718349308	0.184414005134186	.	.	.	.
SKCM	CAediting_1454323	chr21_42843513_-	.	.	.	.	0.0472780064965443	0.188734724370755
CESC	CAediting_1454326	chr21_42843526_-	0.0343194858705702	0.20482166358663	.	.	.	.
ESCA	CAediting_1454329	chr21_42843549_-	.	.	.	.	0.0327809785608743	0.271524099410511
BRCA	CAediting_1454360	chr21_42843679_-	0.0243759671982592	0.163726742386032	.	.	.	.
COAD	CAediting_1454360	chr21_42843679_-	0.0295934948629647	0.2565658723238	.	.	.	.
OV	CAediting_1454360	chr21_42843679_-	0.0237313390118924	0.189062467202697	.	.	.	.
OV	CAediting_1454361	chr21_42843680_-	0.0482243358387411	0.242282575334149	.	.	.	.
BLCA	CAediting_1454363	chr21_42843685_-	.	.	0.0274976718718862	0.166662589527118	.	.
LUAD	CAediting_1454363	chr21_42843685_-	0.00244595773657503	0.288682156928616	.	.	.	.
COAD	CAediting_1454363	chr21_42843685_-	0.0154510100538262	0.192379098779008	.	.	.	.
OV	CAediting_1454363	chr21_42843685_-	0.025962496184424	0.156678568523117	.	.	.	.
SKCM	CAediting_1454363	chr21_42843685_-	0.00632715994223914	0.193911826064028	0.0186738502711764	0.16745221939576	.	.
TGCT	CAediting_1454363	chr21_42843685_-	0.000612364194095308	0.345207123780283	.	.	.	.
LGG	CAediting_1454364	chr21_42843688_-	.	.	.	.	0.0166843350823753	0.250367352334001
BRCA	CAediting_1454364	chr21_42843688_-	0.00042426402334361	0.170414852302346	.	.	.	.
COAD	CAediting_1454364	chr21_42843688_-	0.00869422458253277	0.201853286638378	.	.	.	.
HNSC	CAediting_1454364	chr21_42843688_-	0.00975217593962645	0.199478353896447	.	.	.	.
SKCM	CAediting_1454364	chr21_42843688_-	0.000242791082564787	0.241292931536559	.	.	.	.
READ	CAediting_1454364	chr21_42843688_-	0.0310368053941494	0.278735848164724	.	.	.	.
TGCT	CAediting_1454364	chr21_42843688_-	0.011567712822718	0.241058645889412	.	.	.	.
BRCA	CAediting_1454365	chr21_42843689_-	0.012126777626372	0.12363340393476	.	.	.	.
CESC	CAediting_1454365	chr21_42843689_-	0.00917991072669555	0.200453986539156	.	.	.	.
LUAD	CAediting_1454365	chr21_42843689_-	0.0063494220987078	0.248860550753859	.	.	.	.
COAD	CAediting_1454365	chr21_42843689_-	0.000149865266568324	0.296229476702471	.	.	.	.
SKCM	CAediting_1454365	chr21_42843689_-	0.0083911623464302	0.182769459055732	.	.	.	.
TGCT	CAediting_1454365	chr21_42843689_-	0.0375854201222475	0.200382856115038	.	.	.	.
BRCA	CAediting_1454370	chr21_42843730_-	.	.	.	.	0.00379004791275978	0.371283582174678
LGG	CAediting_1454391	chr21_42843799_-	.	.	0.0439440636589359	0.275274996277028	.	.
BLCA	CAediting_1454413	chr21_42843955_-	.	.	.	.	0.0183639910419649	0.329115012251267
BRCA	CAediting_1454420	chr21_42845888_-	0.00654650882004067	0.212825497786142	.	.	.	.
HNSC	CAediting_1454421	chr21_42845889_-	0.00739625379220362	0.249626949556043	.	.	.	.
SKCM	CAediting_1454421	chr21_42845889_-	0.0110391102334521	0.245960110227488	.	.	.	.
SKCM	CAediting_1454424	chr21_42845912_-	.	.	.	.	0.0462056248212071	0.213108086954321
LGG	CAediting_1454425	chr21_42845915_-	.	.	0.0344470703803845	0.228363689919125	.	.
CESC	CAediting_1454425	chr21_42845915_-	0.0263298132325514	0.267409565089251	.	.	.	.
LGG	CAediting_1454426	chr21_42845916_-	.	.	9.06042157879611e-06	0.448971167290961	.	.
CESC	CAediting_1454432	chr21_42846032_-	0.0153453414937146	0.31969031229127	.	.	.	.
OV	CAediting_1454432	chr21_42846032_-	0.00199557720780376	0.224638547630985	.	.	.	.
OV	CAediting_1454434	chr21_42846049_-	0.0402203306575473	0.176813732905143	.	.	.	.
ESCA	CAediting_1454441	chr21_42846125_-	0.0324783949500523	0.276485325280636	.	.	.	.
STAD	CAediting_1454446	chr21_42846618_-	0.0226255393407588	0.209755836545229	.	.	.	.
ESCA	CAediting_1454446	chr21_42846618_-	.	.	9.85745969492147e-05	0.481418632528454	.	.
OV	CAediting_1454446	chr21_42846618_-	0.00274222922714603	0.308827304816536	.	.	.	.
BLCA	CAediting_1454461	chr21_42846777_-	0.032960467922423	0.203523752127775	.	.	.	.
BRCA	CAediting_1454461	chr21_42846777_-	0.00701054500508358	0.133464812539867	.	.	.	.
STAD	CAediting_1454461	chr21_42846777_-	0.00893018469633656	0.165060492295064	.	.	.	.
SKCM	CAediting_1454461	chr21_42846777_-	0.0429912949659141	0.135354819952897	.	.	.	.
STAD	CAediting_1454472	chr21_42846900_-	0.0489264732654446	0.164417049224294	.	.	.	.
STAD	CAediting_1454481	chr21_42846992_-	0.0328297497642665	0.2084739845488	.	.	.	.

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Relation with cancer stages for WDR4

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BLCA	pathologic_stage	CAediting_1454363	chr21_42843685_-	0.00337118213971275	0.221718963881049
BLCA	pathologic_stage	CAediting_1454364	chr21_42843688_-	0.0107311531945044	0.181418569242483
BRCA	pathologic_stage	CAediting_1454433	chr21_42846037_-	0.00678056110989327	-0.221653771029077
COAD	pathologic_stage	CAediting_1454360	chr21_42843679_-	0.0442554938990012	-0.239504714026714
COAD	pathologic_stage	CAediting_1454420	chr21_42845888_-	0.0105683289563315	0.345226182748467
ESCA	pathologic_stage	CAediting_1454363	chr21_42843685_-	0.0162815865705481	0.235117620457543
ESCA	pathologic_stage	CAediting_1454454	chr21_42846661_-	0.0174111037209703	0.266916836073714
HNSC	clinical_stage	CAediting_1454432	chr21_42846032_-	0.0334951385573638	0.211784752593728
HNSC	pathologic_stage	CAediting_1454425	chr21_42845915_-	0.0150820261996542	0.230182753228525
HNSC	pathologic_stage	CAediting_1454461	chr21_42846777_-	0.0298783534481656	0.181054476123187
KIRC	pathologic_stage	CAediting_1454317	chr21_42843483_-	0.0474766332209573	0.17155637696059
OV	clinical_stage	CAediting_1454329	chr21_42843549_-	0.0488569275909669	-0.189150084511607
OV	clinical_stage	CAediting_1454360	chr21_42843679_-	0.0209093779598826	0.193691480497801
OV	clinical_stage	CAediting_1454363	chr21_42843685_-	0.0347108571379209	0.149418125993794
OV	clinical_stage	CAediting_1454446	chr21_42846618_-	0.0369447763847297	0.220292993327428
SKCM	pathologic_stage	CAediting_1454326	chr21_42843526_-	0.00106049337178371	0.309423333291171
SKCM	pathologic_stage	CAediting_1454364	chr21_42843688_-	0.031977776866233	0.153266095185372
SKCM	pathologic_stage	CAediting_1454425	chr21_42845915_-	0.00109614880931467	0.317193710475921
STAD	pathologic_stage	CAediting_1454318	chr21_42843484_-	0.00821961904351564	-0.176189206316199
STAD	pathologic_stage	CAediting_1454446	chr21_42846618_-	0.0446272606531358	-0.186027053851511
TGCT	pathologic_stage	CAediting_1454316	chr21_42843471_-	0.0197579124319453	-0.276128067914464
THCA	pathologic_stage	CAediting_1454317	chr21_42843483_-	0.0379611930723064	0.152304284250092
THCA	pathologic_stage	CAediting_1454318	chr21_42843484_-	0.0103211262263047	0.15251925907122

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Relation with survival for WDR4

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
LUSC	CAediting_1454317	chr21_42843483_-	0.0442206323426089	0.0246584	0.0544153
STAD	CAediting_1454360	chr21_42843679_-	0.00228462585448452	0.00807426	0.00177219
ESCA	CAediting_1454326	chr21_42843526_-	0.00466081321266298	0.0494305	41.0536
ESCA	CAediting_1454364	chr21_42843688_-	0.0119171375666356	0.0132412	13.7308
OV	CAediting_1454425	chr21_42845915_-	0.0391625997809896	0.0459777	24.3772
SARC	CAediting_1454318	chr21_42843484_-	0.00531316062120968	0.00713905	0.0846837

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RelatedDrugs for WDR4

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for WDR4

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
WDR4	C0013336	Dwarfism	1	GENOMICS_ENGLAND
WDR4	C0265202	Seckel syndrome	1	GENOMICS_ENGLAND
WDR4	C0342573	PITUITARY DWARFISM I	1	GENOMICS_ENGLAND
WDR4	C0795949	Galloway Mowat syndrome	1	ORPHANET
WDR4	C1292778	Chronic myeloproliferative disorder	1	GENOMICS_ENGLAND
WDR4	C3714756	Intellectual Disability	1	GENOMICS_ENGLAND

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene