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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

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Relation with ADAR

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Relation with cancer stages

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Relation with survival state

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Related drugs with this gene

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Related diseases with this gene

Editing gene: RN7SL731P (CAeditome ID:107048981)

Gene summary for RN7SL731P

check button Gene summary
Gene informationGene symbol

RN7SL731P

Gene ID

107048981

Gene nameRNA, 7SL, cytoplasmic 731, pseudogene
Synonyms-
Cytomap

1p36.22

Type of genepseudo
Description-
Modification date20210518
UniProtAcc

.

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for RN7SL731P

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000264501.2
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_11227(10306496, +), CAediting_11228(10306504, +), CAediting_11229(10306513, +), CAediting_11230(10306514, +), CAediting_11231(10306517, +), CAediting_11232(10306520, +), CAediting_11233(10306529, +), CAediting_11234(10306555, +),

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RNA editing positional annotations for RN7SL731P using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_11227chr1_10306496_+ncRNA_exonic
CAediting_11228chr1_10306504_+ncRNA_exonic
CAediting_11229chr1_10306513_+ncRNA_exonic
CAediting_11230chr1_10306514_+ncRNA_exonic
CAediting_11231chr1_10306517_+ncRNA_exonic
CAediting_11232chr1_10306520_+ncRNA_exonic
CAediting_11233chr1_10306529_+ncRNA_exonic
CAediting_11234chr1_10306555_+ncRNA_exonic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_11227chr1_10306496_+srpRNAsrpRNA7SLRNA
CAediting_11228chr1_10306504_+srpRNAsrpRNA7SLRNA
CAediting_11229chr1_10306513_+srpRNAsrpRNA7SLRNA
CAediting_11230chr1_10306514_+srpRNAsrpRNA7SLRNA
CAediting_11231chr1_10306517_+srpRNAsrpRNA7SLRNA
CAediting_11232chr1_10306520_+srpRNAsrpRNA7SLRNA
CAediting_11233chr1_10306529_+srpRNAsrpRNA7SLRNA
CAediting_11234chr1_10306555_+srpRNAsrpRNA7SLRNA

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RNA A-to-I editing events in the alternative splicing sites for RN7SL731P

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000264501.2.RN7SL731P.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000264501.2.RN7SL731P.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RN7SL731P

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for RN7SL731P

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for RN7SL731P

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for RN7SL731P

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000584329.2misc_RNASoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_11227ENST00000584329.2chr1_10306496_+-105.60-104.80-117.30
CAediting_11228ENST00000584329.2chr1_10306504_+-106.30-104.80-117.30
CAediting_11229ENST00000584329.2chr1_10306513_+-107.20-104.80-117.30
CAediting_11230ENST00000584329.2chr1_10306514_+-107.20-104.80-117.30
CAediting_11231ENST00000584329.2chr1_10306517_+-106.60-104.80-117.30
CAediting_11232ENST00000584329.2chr1_10306520_+-104.50-104.80-117.30
CAediting_11233ENST00000584329.2chr1_10306529_+-107.30-104.80-117.30
CAediting_11234ENST00000584329.2chr1_10306555_+-107.80-104.80-117.30

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Relation with ADAR for RN7SL731P

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
LGGCAediting_11230chr1_10306514_+0.01055327540819460.193972834306966....
BRCACAediting_11230chr1_10306514_+0.02972389757230630.128341430046091....
LUADCAediting_11230chr1_10306514_+9.40559460443975e-070.404601147767274....
TGCTCAediting_11230chr1_10306514_+0.0002631009009431980.447765684901547....

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Relation with cancer stages for RN7SL731P

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
BLCApathologic_stageCAediting_11230chr1_10306514_+0.0446174432263149-0.213430959851877
HNSCpathologic_stageCAediting_11230chr1_10306514_+0.005915434145807110.210903956611994
LUSCpathologic_stageCAediting_11230chr1_10306514_+0.03870066032249250.155108564279434
TGCTpathologic_stageCAediting_11230chr1_10306514_+0.01802317982537220.415529848365047

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Relation with survival for RN7SL731P

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for RN7SL731P

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for RN7SL731P

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource