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Editing gene: CNPY3 (CAeditome ID:10695)

Gene summary for CNPY3

Gene summary

Gene information	Gene symbol	CNPY3
	Gene ID	10695
	Gene name	canopy FGF signaling regulator 3
	Synonyms	CAG4A\|DEE60\|EIEE60\|ERDA5\|PRAT4A\|TNRC5
	Cytomap	6p21.1
	Type of gene	protein-coding
	Description	protein canopy homolog 3CAG repeat containingCTG repeat protein 4aexpanded repeat-domain protein CAG/CTG 5protein associated with TLR4protein associated with Toll-like receptor 4Atrinucleotide repeat-containing gene 5 protein
	Modification date	20210518
	UniProtAcc	Q9BT09
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for CNPY3

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000137161.15

RNA A-to-I editing events in Cancer.

CAediting_482613(42931087, +), CAediting_482614(42931092, +), CAediting_482615(42931278, +), CAediting_482616(42933907, +), CAediting_482617(42933915, +), CAediting_482618(42933916, +), CAediting_482619(42933921, +), CAediting_482620(42933969, +), CAediting_482621(42933970, +), CAediting_482622(42933975, +), CAediting_482623(42933980, +), CAediting_482624(42933984, +), CAediting_482625(42933988, +), CAediting_482626(42934008, +), CAediting_482627(42934010, +), CAediting_482628(42934048, +), CAediting_482629(42934049, +), CAediting_482630(42934058, +), CAediting_482631(42934109, +), CAediting_482632(42934142, +), CAediting_482633(42934143, +), CAediting_482634(42934895, +), CAediting_482635(42934982, +), CAediting_482636(42935004, +), CAediting_482637(42935059, +), CAediting_482638(42935068, +), CAediting_482639(42935077, +), CAediting_482640(42935130, +), CAediting_482641(42936553, +), CAediting_482642(42936557, +), CAediting_482643(42936559, +), CAediting_482644(42936565, +), CAediting_482645(42936580, +), CAediting_482646(42936591, +), CAediting_482647(42936605, +), CAediting_482648(42936622, +), CAediting_482649(42936631, +), CAediting_482650(42936635, +), CAediting_482651(42936648, +), CAediting_482652(42936653, +), CAediting_482653(42936665, +), CAediting_482654(42936675, +), CAediting_482655(42936677, +), CAediting_482656(42936685, +), CAediting_482657(42936734, +), CAediting_482658(42936737, +), CAediting_482659(42936746, +), CAediting_482660(42936798, +), CAediting_482661(42936810, +), CAediting_482662(42936812, +), CAediting_482663(42936816, +), CAediting_482664(42937325, +), CAediting_482665(42937347, +), CAediting_482666(42937375, +), CAediting_482667(42937396, +), CAediting_482668(42937402, +), CAediting_482669(42937404, +), CAediting_482670(42937413, +), CAediting_482671(42937416, +), CAediting_482672(42937417, +), CAediting_482673(42937422, +), CAediting_482674(42937424, +), CAediting_482675(42937447, +), CAediting_482676(42937473, +), CAediting_482677(42937479, +), CAediting_482678(42937496, +), CAediting_482679(42937500, +), CAediting_482680(42937503, +), CAediting_482681(42937504, +), CAediting_482682(42937514, +), CAediting_482683(42937522, +), CAediting_482684(42937526, +), CAediting_482685(42937571, +), CAediting_482686(42937573, +),

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RNA editing positional annotations for CNPY3 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_482613	chr6_42931087_+	intronic
CAediting_482614	chr6_42931092_+	intronic
CAediting_482615	chr6_42931278_+	intronic
CAediting_482616	chr6_42933907_+	intronic
CAediting_482617	chr6_42933915_+	intronic
CAediting_482618	chr6_42933916_+	intronic
CAediting_482619	chr6_42933921_+	intronic
CAediting_482620	chr6_42933969_+	intronic
CAediting_482621	chr6_42933970_+	intronic
CAediting_482622	chr6_42933975_+	intronic
CAediting_482623	chr6_42933980_+	intronic
CAediting_482624	chr6_42933984_+	intronic
CAediting_482625	chr6_42933988_+	intronic
CAediting_482626	chr6_42934008_+	intronic
CAediting_482627	chr6_42934010_+	intronic
CAediting_482628	chr6_42934048_+	intronic
CAediting_482629	chr6_42934049_+	intronic
CAediting_482630	chr6_42934058_+	intronic
CAediting_482631	chr6_42934109_+	intronic
CAediting_482632	chr6_42934142_+	intronic
CAediting_482633	chr6_42934143_+	intronic
CAediting_482634	chr6_42934895_+	intronic
CAediting_482635	chr6_42934982_+	intronic
CAediting_482636	chr6_42935004_+	intronic
CAediting_482637	chr6_42935059_+	intronic
CAediting_482638	chr6_42935068_+	intronic
CAediting_482639	chr6_42935077_+	intronic
CAediting_482640	chr6_42935130_+	intronic
CAediting_482641	chr6_42936553_+	intronic
CAediting_482642	chr6_42936557_+	intronic
CAediting_482643	chr6_42936559_+	intronic
CAediting_482644	chr6_42936565_+	intronic
CAediting_482645	chr6_42936580_+	intronic
CAediting_482646	chr6_42936591_+	intronic
CAediting_482647	chr6_42936605_+	intronic
CAediting_482648	chr6_42936622_+	intronic
CAediting_482649	chr6_42936631_+	intronic
CAediting_482650	chr6_42936635_+	intronic
CAediting_482651	chr6_42936648_+	intronic
CAediting_482652	chr6_42936653_+	intronic
CAediting_482653	chr6_42936665_+	intronic
CAediting_482654	chr6_42936675_+	intronic
CAediting_482655	chr6_42936677_+	intronic
CAediting_482656	chr6_42936685_+	intronic
CAediting_482657	chr6_42936734_+	intronic
CAediting_482658	chr6_42936737_+	intronic
CAediting_482659	chr6_42936746_+	intronic
CAediting_482660	chr6_42936798_+	intronic
CAediting_482661	chr6_42936810_+	intronic
CAediting_482662	chr6_42936812_+	intronic
CAediting_482663	chr6_42936816_+	intronic
CAediting_482664	chr6_42937325_+	intronic
CAediting_482665	chr6_42937347_+	intronic
CAediting_482666	chr6_42937375_+	intronic
CAediting_482667	chr6_42937396_+	intronic
CAediting_482668	chr6_42937402_+	intronic
CAediting_482669	chr6_42937404_+	intronic
CAediting_482670	chr6_42937413_+	intronic
CAediting_482671	chr6_42937416_+	intronic
CAediting_482672	chr6_42937417_+	intronic
CAediting_482673	chr6_42937422_+	intronic
CAediting_482674	chr6_42937424_+	intronic
CAediting_482675	chr6_42937447_+	intronic
CAediting_482676	chr6_42937473_+	intronic
CAediting_482677	chr6_42937479_+	intronic
CAediting_482678	chr6_42937496_+	intronic
CAediting_482679	chr6_42937500_+	intronic
CAediting_482680	chr6_42937503_+	intronic
CAediting_482681	chr6_42937504_+	intronic
CAediting_482682	chr6_42937514_+	intronic
CAediting_482683	chr6_42937522_+	intronic
CAediting_482684	chr6_42937526_+	intronic
CAediting_482685	chr6_42937571_+	intronic
CAediting_482686	chr6_42937573_+	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_482613	chr6_42931087_+	SINE	Alu	AluSz
CAediting_482614	chr6_42931092_+	SINE	Alu	AluSz
CAediting_482615	chr6_42931278_+	SINE	Alu	AluSp
CAediting_482616	chr6_42933907_+	SINE	Alu	AluSq2
CAediting_482617	chr6_42933915_+	SINE	Alu	AluSq2
CAediting_482618	chr6_42933916_+	SINE	Alu	AluSq2
CAediting_482619	chr6_42933921_+	SINE	Alu	AluSq2
CAediting_482620	chr6_42933969_+	SINE	Alu	AluSq2
CAediting_482621	chr6_42933970_+	SINE	Alu	AluSq2
CAediting_482622	chr6_42933975_+	SINE	Alu	AluSq2
CAediting_482623	chr6_42933980_+	SINE	Alu	AluSq2
CAediting_482624	chr6_42933984_+	SINE	Alu	AluSq2
CAediting_482625	chr6_42933988_+	SINE	Alu	AluSq2
CAediting_482626	chr6_42934008_+	SINE	Alu	AluSq2
CAediting_482627	chr6_42934010_+	SINE	Alu	AluSq2
CAediting_482628	chr6_42934048_+	SINE	Alu	AluSq2
CAediting_482629	chr6_42934049_+	SINE	Alu	AluSq2
CAediting_482630	chr6_42934058_+	SINE	Alu	AluSq2
CAediting_482631	chr6_42934109_+	SINE	Alu	AluSq2
CAediting_482632	chr6_42934142_+	SINE	Alu	AluSq2
CAediting_482633	chr6_42934143_+	SINE	Alu	AluSq2
CAediting_482634	chr6_42934895_+	SINE	Alu	AluSq2
CAediting_482635	chr6_42934982_+	SINE	Alu	AluSq2
CAediting_482636	chr6_42935004_+	SINE	Alu	AluSq2
CAediting_482637	chr6_42935059_+	SINE	Alu	AluSq2
CAediting_482638	chr6_42935068_+	SINE	Alu	AluSq2
CAediting_482639	chr6_42935077_+	SINE	Alu	AluSq2
CAediting_482640	chr6_42935130_+	SINE	Alu	AluSq2
CAediting_482641	chr6_42936553_+	SINE	Alu	AluSx1
CAediting_482642	chr6_42936557_+	SINE	Alu	AluSx1
CAediting_482643	chr6_42936559_+	SINE	Alu	AluSx1
CAediting_482644	chr6_42936565_+	SINE	Alu	AluSx1
CAediting_482645	chr6_42936580_+	SINE	Alu	AluSx1
CAediting_482646	chr6_42936591_+	SINE	Alu	AluSx1
CAediting_482647	chr6_42936605_+	SINE	Alu	AluSx1
CAediting_482648	chr6_42936622_+	SINE	Alu	AluSx1
CAediting_482649	chr6_42936631_+	SINE	Alu	AluSx1
CAediting_482650	chr6_42936635_+	SINE	Alu	AluSx1
CAediting_482651	chr6_42936648_+	SINE	Alu	AluSx1
CAediting_482652	chr6_42936653_+	SINE	Alu	AluSx1
CAediting_482653	chr6_42936665_+	SINE	Alu	AluSx1
CAediting_482654	chr6_42936675_+	SINE	Alu	AluSx1
CAediting_482655	chr6_42936677_+	SINE	Alu	AluSx1
CAediting_482656	chr6_42936685_+	SINE	Alu	AluSx1
CAediting_482657	chr6_42936734_+	SINE	Alu	AluSx1
CAediting_482658	chr6_42936737_+	SINE	Alu	AluSx1
CAediting_482659	chr6_42936746_+	SINE	Alu	AluSx1
CAediting_482660	chr6_42936798_+	SINE	Alu	AluSx1
CAediting_482661	chr6_42936810_+	SINE	Alu	AluSx1
CAediting_482662	chr6_42936812_+	SINE	Alu	AluSx1
CAediting_482663	chr6_42936816_+	SINE	Alu	AluSx1
CAediting_482664	chr6_42937325_+	SINE	Alu	AluSz6
CAediting_482665	chr6_42937347_+	SINE	Alu	AluSz6
CAediting_482666	chr6_42937375_+	SINE	Alu	AluSz6
CAediting_482667	chr6_42937396_+	SINE	Alu	AluSz6
CAediting_482668	chr6_42937402_+	SINE	Alu	AluSz6
CAediting_482669	chr6_42937404_+	SINE	Alu	AluSz6
CAediting_482670	chr6_42937413_+	SINE	Alu	AluSz6
CAediting_482671	chr6_42937416_+	SINE	Alu	AluSz6
CAediting_482672	chr6_42937417_+	SINE	Alu	AluSz6
CAediting_482673	chr6_42937422_+	SINE	Alu	AluSz6
CAediting_482674	chr6_42937424_+	SINE	Alu	AluSz6
CAediting_482675	chr6_42937447_+	SINE	Alu	AluSz6
CAediting_482676	chr6_42937473_+	SINE	Alu	AluSz6
CAediting_482677	chr6_42937479_+	SINE	Alu	AluSz6
CAediting_482678	chr6_42937496_+	SINE	Alu	AluSz6
CAediting_482679	chr6_42937500_+	SINE	Alu	AluSz6
CAediting_482680	chr6_42937503_+	SINE	Alu	AluSz6
CAediting_482681	chr6_42937504_+	SINE	Alu	AluSz6
CAediting_482682	chr6_42937514_+	SINE	Alu	AluSz6
CAediting_482683	chr6_42937522_+	SINE	Alu	AluSz6
CAediting_482684	chr6_42937526_+	SINE	Alu	AluSz6
CAediting_482685	chr6_42937571_+	SINE	Alu	AluSz6
CAediting_482686	chr6_42937573_+	SINE	Alu	AluSz6

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RNA A-to-I editing events in the alternative splicing sites for CNPY3

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000137161.15.CNPY3.

Correlation between RNA A-to-I editing and PSI for ENSG00000137161.15.CNPY3.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CNPY3

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

LAML.CAediting_482651.ENSG00000137161.CNPY3.png
Soverview

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Protein coding region RNA A-to-I editings for CNPY3

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for CNPY3

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_396018	chr5_1062918_-	ENSG00000137161.15	ENST00000394142	hsa-miR-4635	42937826	42937833	8mer-1a	42937813	42937833	163	-28.04

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CNPY3

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for CNPY3

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for CNPY3

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for CNPY3

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for CNPY3

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for CNPY3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
CNPY3	C0037769	West Syndrome	1	ORPHANET
CNPY3	C4693663	EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 60	1	GENOMICS_ENGLAND;UNIPROT

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene