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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: FARS2 (CAeditome ID:10667)

Gene summary for FARS2

check button Gene summary
Gene informationGene symbol

FARS2

Gene ID

10667

Gene namephenylalanyl-tRNA synthetase 2, mitochondrial
SynonymsCOXPD14|FARS1|HSPC320|PheRS|SPG77|mtPheRS
Cytomap

6p25.1

Type of geneprotein-coding
Descriptionphenylalanine--tRNA ligase, mitochondrialdJ236A3.1 (phenylalanine-tRNA synthetase)dJ520B18.2 (FARS1 (phenylalanine-tRNA synthetase))mitochondrial PHERSphenylalanine tRNA ligase 2, mitochondrialphenylalanine translasephenylalanine-tRNA synthetase 1 (
Modification date20210518
UniProtAcc

O95363

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
FARS2

GO:0000049

Phenylalanine--tRNA ligase, mitochondrial

10329163

FARS2

GO:0004826

Phenylalanine--tRNA ligase, mitochondrial

10329163

FARS2

GO:0006432

Phenylalanine--tRNA ligase, mitochondrial

10329163

FARS2

GO:0008033

Phenylalanine--tRNA ligase, mitochondrial

10329163


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RNA A-to-I events for FARS2

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000145982.10

check button RNA A-to-I editing events in Cancer.
CAediting_457318(5264094, +), CAediting_457319(5264132, +), CAediting_457320(5264136, +), CAediting_457321(5264156, +), CAediting_457322(5264874, +), CAediting_457323(5264927, +), CAediting_457324(5264995, +), CAediting_457325(5266411, +), CAediting_457326(5266437, +), CAediting_457327(5267489, +), CAediting_457328(5267501, +), CAediting_457329(5267591, +), CAediting_457330(5267633, +), CAediting_457331(5267639, +), CAediting_457332(5267643, +), CAediting_457333(5267704, +), CAediting_457334(5267714, +), CAediting_457335(5279128, +), CAediting_457336(5279230, +), CAediting_457337(5279266, +), CAediting_457338(5279283, +), CAediting_457339(5279292, +), CAediting_457340(5279297, +), CAediting_457341(5279298, +), CAediting_457342(5279332, +), CAediting_457343(5283144, +), CAediting_457344(5283213, +), CAediting_457345(5283253, +), CAediting_457346(5283266, +), CAediting_457347(5283402, +), CAediting_457348(5283470, +), CAediting_457349(5286337, +), CAediting_457350(5290782, +), CAediting_457351(5290849, +), CAediting_457352(5291640, +), CAediting_457353(5291658, +), CAediting_457354(5291661, +), CAediting_457355(5291697, +), CAediting_457356(5291698, +), CAediting_457357(5296271, +), CAediting_457358(5300740, +), CAediting_457359(5301314, +), CAediting_457360(5301376, +), CAediting_457361(5342538, +), CAediting_457362(5342592, +), CAediting_457363(5342593, +), CAediting_457364(5342594, +), CAediting_457365(5342609, +), CAediting_457366(5343329, +), CAediting_457367(5343373, +), CAediting_457368(5343377, +), CAediting_457369(5363206, +), CAediting_457370(5434179, +), CAediting_457371(5434359, +), CAediting_457372(5444302, +), CAediting_457373(5444399, +), CAediting_457374(5444412, +), CAediting_457375(5449154, +), CAediting_457376(5449202, +), CAediting_457377(5547927, +), CAediting_457378(5548022, +), CAediting_457379(5548025, +), CAediting_457380(5548028, +), CAediting_457381(5555259, +), CAediting_457382(5578585, +), CAediting_457383(5578626, +), CAediting_457384(5578652, +), CAediting_457385(5580229, +), CAediting_457386(5602526, +), CAediting_457387(5602553, +), CAediting_457388(5603135, +), CAediting_457389(5603165, +), CAediting_457390(5603199, +), CAediting_457391(5603207, +), CAediting_457392(5603208, +), CAediting_457393(5621137, +), CAediting_457394(5621139, +), CAediting_457395(5621141, +), CAediting_457396(5621220, +), CAediting_457397(5649050, +), CAediting_457398(5649053, +), CAediting_457399(5649067, +), CAediting_457400(5649071, +), CAediting_457401(5649075, +), CAediting_457402(5649076, +), CAediting_457403(5649081, +), CAediting_457404(5649099, +), CAediting_457405(5649107, +), CAediting_457406(5649114, +), CAediting_457407(5649150, +), CAediting_457408(5649162, +), CAediting_457409(5649165, +), CAediting_457410(5649183, +), CAediting_457411(5649187, +), CAediting_457412(5649191, +), CAediting_457413(5649195, +), CAediting_457414(5649219, +), CAediting_457415(5649243, +), CAediting_457416(5649248, +), CAediting_457417(5649249, +), CAediting_457418(5650318, +), CAediting_457419(5650339, +), CAediting_457420(5650364, +), CAediting_457421(5650371, +), CAediting_457422(5650372, +), CAediting_457423(5650379, +), CAediting_457424(5650398, +), CAediting_457425(5650399, +), CAediting_457426(5650406, +), CAediting_457427(5650407, +), CAediting_457428(5650416, +), CAediting_457429(5650417, +), CAediting_457430(5650421, +), CAediting_457431(5650422, +), CAediting_457432(5650451, +), CAediting_457433(5650454, +), CAediting_457434(5650459, +), CAediting_457435(5650503, +), CAediting_457436(5658042, +), CAediting_457437(5658051, +), CAediting_457438(5658055, +), CAediting_457439(5658092, +), CAediting_457440(5658097, +), CAediting_457441(5658135, +), CAediting_457442(5658136, +), CAediting_457443(5658141, +), CAediting_457444(5658149, +), CAediting_457445(5658158, +), CAediting_457446(5658177, +), CAediting_457447(5718044, +), CAediting_457448(5718045, +), CAediting_457449(5718055, +), CAediting_457450(5718080, +), CAediting_457451(5718097, +), CAediting_457452(5719114, +), CAediting_457453(5719125, +), CAediting_457454(5719127, +), CAediting_457455(5719128, +), CAediting_457456(5719136, +), CAediting_457457(5719144, +), CAediting_457458(5719150, +), CAediting_457459(5719154, +), CAediting_457460(5719155, +), CAediting_457461(5719168, +), CAediting_457462(5719173, +), CAediting_457463(5719176, +), CAediting_457464(5719181, +), CAediting_457465(5719182, +), CAediting_457466(5719187, +), CAediting_457467(5719197, +), CAediting_457468(5719205, +), CAediting_457469(5719218, +), CAediting_457470(5719225, +), CAediting_457471(5719231, +), CAediting_457472(5719232, +), CAediting_457473(5719233, +), CAediting_457474(5719236, +), CAediting_457475(5719256, +), CAediting_457476(5719272, +), CAediting_457477(5719279, +), CAediting_457478(5719285, +), CAediting_457479(5719292, +), CAediting_457480(5719321, +), CAediting_457481(5719339, +), CAediting_457482(5719345, +), CAediting_457483(5719347, +), CAediting_457484(5720774, +), CAediting_457485(5738090, +), CAediting_457486(5739267, +),

Top

RNA editing positional annotations for FARS2 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_457318chr6_5264094_+intronic
CAediting_457319chr6_5264132_+intronic
CAediting_457320chr6_5264136_+intronic
CAediting_457321chr6_5264156_+intronic
CAediting_457322chr6_5264874_+intronic
CAediting_457323chr6_5264927_+intronic
CAediting_457324chr6_5264995_+intronic
CAediting_457325chr6_5266411_+intronic
CAediting_457326chr6_5266437_+intronic
CAediting_457327chr6_5267489_+intronic
CAediting_457328chr6_5267501_+intronic
CAediting_457329chr6_5267591_+intronic
CAediting_457330chr6_5267633_+intronic
CAediting_457331chr6_5267639_+intronic
CAediting_457332chr6_5267643_+intronic
CAediting_457333chr6_5267704_+intronic
CAediting_457334chr6_5267714_+intronic
CAediting_457335chr6_5279128_+intronic
CAediting_457336chr6_5279230_+intronic
CAediting_457337chr6_5279266_+intronic
CAediting_457338chr6_5279283_+intronic
CAediting_457339chr6_5279292_+intronic
CAediting_457340chr6_5279297_+intronic
CAediting_457341chr6_5279298_+intronic
CAediting_457342chr6_5279332_+intronic
CAediting_457343chr6_5283144_+intronic
CAediting_457344chr6_5283213_+intronic
CAediting_457345chr6_5283253_+intronic
CAediting_457346chr6_5283266_+intronic
CAediting_457347chr6_5283402_+intronic
CAediting_457348chr6_5283470_+intronic
CAediting_457349chr6_5286337_+intronic
CAediting_457350chr6_5290782_+intronic
CAediting_457351chr6_5290849_+intronic
CAediting_457352chr6_5291640_+intronic
CAediting_457353chr6_5291658_+intronic
CAediting_457354chr6_5291661_+intronic
CAediting_457355chr6_5291697_+intronic
CAediting_457356chr6_5291698_+intronic
CAediting_457357chr6_5296271_+intronic
CAediting_457358chr6_5300740_+intronic
CAediting_457359chr6_5301314_+intronic
CAediting_457360chr6_5301376_+intronic
CAediting_457361chr6_5342538_+intronic
CAediting_457362chr6_5342592_+intronic
CAediting_457363chr6_5342593_+intronic
CAediting_457364chr6_5342594_+intronic
CAediting_457365chr6_5342609_+intronic
CAediting_457366chr6_5343329_+intronic
CAediting_457367chr6_5343373_+intronic
CAediting_457368chr6_5343377_+intronic
CAediting_457369chr6_5363206_+intronic
CAediting_457370chr6_5434179_+intronic
CAediting_457371chr6_5434359_+intronic
CAediting_457372chr6_5444302_+intronic
CAediting_457373chr6_5444399_+intronic
CAediting_457374chr6_5444412_+intronic
CAediting_457375chr6_5449154_+intronic
CAediting_457376chr6_5449202_+intronic
CAediting_457377chr6_5547927_+intronic
CAediting_457378chr6_5548022_+intronic
CAediting_457379chr6_5548025_+intronic
CAediting_457380chr6_5548028_+intronic
CAediting_457381chr6_5555259_+intronic
CAediting_457382chr6_5578585_+intronic
CAediting_457383chr6_5578626_+intronic
CAediting_457384chr6_5578652_+intronic
CAediting_457385chr6_5580229_+intronic
CAediting_457386chr6_5602526_+intronic
CAediting_457387chr6_5602553_+intronic
CAediting_457388chr6_5603135_+intronic
CAediting_457389chr6_5603165_+intronic
CAediting_457390chr6_5603199_+intronic
CAediting_457391chr6_5603207_+intronic
CAediting_457392chr6_5603208_+intronic
CAediting_457393chr6_5621137_+intronic
CAediting_457394chr6_5621139_+intronic
CAediting_457395chr6_5621141_+intronic
CAediting_457396chr6_5621220_+intronic
CAediting_457397chr6_5649050_+intronic
CAediting_457398chr6_5649053_+intronic
CAediting_457399chr6_5649067_+intronic
CAediting_457400chr6_5649071_+intronic
CAediting_457401chr6_5649075_+intronic
CAediting_457402chr6_5649076_+intronic
CAediting_457403chr6_5649081_+intronic
CAediting_457404chr6_5649099_+intronic
CAediting_457405chr6_5649107_+intronic
CAediting_457406chr6_5649114_+intronic
CAediting_457407chr6_5649150_+intronic
CAediting_457408chr6_5649162_+intronic
CAediting_457409chr6_5649165_+intronic
CAediting_457410chr6_5649183_+intronic
CAediting_457411chr6_5649187_+intronic
CAediting_457412chr6_5649191_+intronic
CAediting_457413chr6_5649195_+intronic
CAediting_457414chr6_5649219_+intronic
CAediting_457415chr6_5649243_+intronic
CAediting_457416chr6_5649248_+intronic
CAediting_457417chr6_5649249_+intronic
CAediting_457418chr6_5650318_+intronic
CAediting_457419chr6_5650339_+intronic
CAediting_457420chr6_5650364_+intronic
CAediting_457421chr6_5650371_+intronic
CAediting_457422chr6_5650372_+intronic
CAediting_457423chr6_5650379_+intronic
CAediting_457424chr6_5650398_+intronic
CAediting_457425chr6_5650399_+intronic
CAediting_457426chr6_5650406_+intronic
CAediting_457427chr6_5650407_+intronic
CAediting_457428chr6_5650416_+intronic
CAediting_457429chr6_5650417_+intronic
CAediting_457430chr6_5650421_+intronic
CAediting_457431chr6_5650422_+intronic
CAediting_457432chr6_5650451_+intronic
CAediting_457433chr6_5650454_+intronic
CAediting_457434chr6_5650459_+intronic
CAediting_457435chr6_5650503_+intronic
CAediting_457436chr6_5658042_+intronic
CAediting_457437chr6_5658051_+intronic
CAediting_457438chr6_5658055_+intronic
CAediting_457439chr6_5658092_+intronic
CAediting_457440chr6_5658097_+intronic
CAediting_457441chr6_5658135_+intronic
CAediting_457442chr6_5658136_+intronic
CAediting_457443chr6_5658141_+intronic
CAediting_457444chr6_5658149_+intronic
CAediting_457445chr6_5658158_+intronic
CAediting_457446chr6_5658177_+intronic
CAediting_457447chr6_5718044_+intronic
CAediting_457448chr6_5718045_+intronic
CAediting_457449chr6_5718055_+intronic
CAediting_457450chr6_5718080_+intronic
CAediting_457451chr6_5718097_+intronic
CAediting_457452chr6_5719114_+intronic
CAediting_457453chr6_5719125_+intronic
CAediting_457454chr6_5719127_+intronic
CAediting_457455chr6_5719128_+intronic
CAediting_457456chr6_5719136_+intronic
CAediting_457457chr6_5719144_+intronic
CAediting_457458chr6_5719150_+intronic
CAediting_457459chr6_5719154_+intronic
CAediting_457460chr6_5719155_+intronic
CAediting_457461chr6_5719168_+intronic
CAediting_457462chr6_5719173_+intronic
CAediting_457463chr6_5719176_+intronic
CAediting_457464chr6_5719181_+intronic
CAediting_457465chr6_5719182_+intronic
CAediting_457466chr6_5719187_+intronic
CAediting_457467chr6_5719197_+intronic
CAediting_457468chr6_5719205_+intronic
CAediting_457469chr6_5719218_+intronic
CAediting_457470chr6_5719225_+intronic
CAediting_457471chr6_5719231_+intronic
CAediting_457472chr6_5719232_+intronic
CAediting_457473chr6_5719233_+intronic
CAediting_457474chr6_5719236_+intronic
CAediting_457475chr6_5719256_+intronic
CAediting_457476chr6_5719272_+intronic
CAediting_457477chr6_5719279_+intronic
CAediting_457478chr6_5719285_+intronic
CAediting_457479chr6_5719292_+intronic
CAediting_457480chr6_5719321_+intronic
CAediting_457481chr6_5719339_+intronic
CAediting_457482chr6_5719345_+intronic
CAediting_457483chr6_5719347_+intronic
CAediting_457484chr6_5720774_+intronic
CAediting_457485chr6_5738090_+intronic
CAediting_457486chr6_5739267_+intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_457318chr6_5264094_+SINEAluAluJb
CAediting_457319chr6_5264132_+SINEAluAluJb
CAediting_457320chr6_5264136_+SINEAluAluJb
CAediting_457321chr6_5264156_+SINEAluAluJb
CAediting_457322chr6_5264874_+SINEAluAluJr4
CAediting_457323chr6_5264927_+SINEAluAluJr4
CAediting_457324chr6_5264995_+SINEAluAluJr4
CAediting_457325chr6_5266411_+SINEAluFLAM_C
CAediting_457326chr6_5266437_+SINEAluFLAM_C
CAediting_457327chr6_5267489_+SINEAluAluY
CAediting_457328chr6_5267501_+SINEAluAluY
CAediting_457329chr6_5267591_+SINEAluAluY
CAediting_457330chr6_5267633_+SINEAluAluY
CAediting_457331chr6_5267639_+SINEAluAluY
CAediting_457332chr6_5267643_+SINEAluAluY
CAediting_457333chr6_5267704_+SINEAluAluY
CAediting_457334chr6_5267714_+SINEAluAluY
CAediting_457335chr6_5279128_+SINEAluAluSc8
CAediting_457336chr6_5279230_+SINEAluAluSc8
CAediting_457337chr6_5279266_+SINEAluAluSc8
CAediting_457338chr6_5279283_+SINEAluAluSc8
CAediting_457339chr6_5279292_+SINEAluAluSc8
CAediting_457340chr6_5279297_+SINEAluAluSc8
CAediting_457341chr6_5279298_+SINEAluAluSc8
CAediting_457342chr6_5279332_+SINEAluAluSc8
CAediting_457343chr6_5283144_+SINEAluAluSp
CAediting_457344chr6_5283213_+SINEAluAluSp
CAediting_457345chr6_5283253_+SINEAluAluSp
CAediting_457346chr6_5283266_+SINEAluAluSp
CAediting_457347chr6_5283402_+SINEAluAluSx1
CAediting_457348chr6_5283470_+SINEAluAluSx1
CAediting_457349chr6_5286337_+SINEAluAluJb
CAediting_457350chr6_5290782_+SINEAluAluJb
CAediting_457351chr6_5290849_+SINEAluAluJb
CAediting_457352chr6_5291640_+SINEAluAluJr
CAediting_457353chr6_5291658_+SINEAluAluJr
CAediting_457354chr6_5291661_+SINEAluAluJr
CAediting_457355chr6_5291697_+SINEAluAluJr
CAediting_457356chr6_5291698_+SINEAluAluJr
CAediting_457357chr6_5296271_+SINEAluAluY
CAediting_457358chr6_5300740_+SINEAluAluJo
CAediting_457359chr6_5301314_+SINEAluAluJo
CAediting_457360chr6_5301376_+SINEAluAluJo
CAediting_457361chr6_5342538_+SINEAluAluSp
CAediting_457362chr6_5342592_+SINEAluAluSp
CAediting_457363chr6_5342593_+SINEAluAluSp
CAediting_457364chr6_5342594_+SINEAluAluSp
CAediting_457365chr6_5342609_+SINEAluAluSp
CAediting_457366chr6_5343329_+SINEAluAluSq
CAediting_457367chr6_5343373_+SINEAluAluSq
CAediting_457368chr6_5343377_+SINEAluAluSq
CAediting_457369chr6_5363206_+SINEAluAluY
CAediting_457370chr6_5434179_+SINEAluAluSx1
CAediting_457371chr6_5434359_+SINEAluAluSx1
CAediting_457372chr6_5444302_+SINEAluAluSg
CAediting_457373chr6_5444399_+SINEAluAluSg
CAediting_457374chr6_5444412_+SINEAluAluSg
CAediting_457375chr6_5449154_+SINEAluAluSx1
CAediting_457376chr6_5449202_+SINEAluAluSx1
CAediting_457377chr6_5547927_+LTRERVL-MaLRTHE1A
CAediting_457378chr6_5548022_+LTRERVL-MaLRTHE1A
CAediting_457379chr6_5548025_+LTRERVL-MaLRTHE1A
CAediting_457380chr6_5548028_+LTRERVL-MaLRTHE1A
CAediting_457381chr6_5555259_+LTRERVL-MaLRTHE1A
CAediting_457382chr6_5578585_+SINEAluAluY
CAediting_457383chr6_5578626_+SINEAluAluY
CAediting_457384chr6_5578652_+SINEAluAluY
CAediting_457385chr6_5580229_+SINEAluAluSg
CAediting_457386chr6_5602526_+SINEAluAluSc
CAediting_457387chr6_5602553_+SINEAluAluSc
CAediting_457388chr6_5603135_+SINEAluAluJb
CAediting_457389chr6_5603165_+SINEAluAluJb
CAediting_457390chr6_5603199_+SINEAluAluJb
CAediting_457391chr6_5603207_+SINEAluAluJb
CAediting_457392chr6_5603208_+SINEAluAluJb
CAediting_457393chr6_5621137_+SINEAluAluJr4
CAediting_457394chr6_5621139_+SINEAluAluJr4
CAediting_457395chr6_5621141_+SINEAluAluJr4
CAediting_457396chr6_5621220_+SINEAluAluJr4
CAediting_457436chr6_5658042_+SINEAluAluSp
CAediting_457437chr6_5658051_+SINEAluAluSp
CAediting_457438chr6_5658055_+SINEAluAluSp
CAediting_457439chr6_5658092_+SINEAluAluSp
CAediting_457440chr6_5658097_+SINEAluAluSp
CAediting_457441chr6_5658135_+SINEAluAluSp
CAediting_457442chr6_5658136_+SINEAluAluSp
CAediting_457443chr6_5658141_+SINEAluAluSp
CAediting_457444chr6_5658149_+SINEAluAluSp
CAediting_457445chr6_5658158_+SINEAluAluSp
CAediting_457446chr6_5658177_+SINEAluAluSp
CAediting_457447chr6_5718044_+SINEAluAluSz
CAediting_457448chr6_5718045_+SINEAluAluSz
CAediting_457449chr6_5718055_+SINEAluAluSz
CAediting_457450chr6_5718080_+SINEAluAluSz
CAediting_457451chr6_5718097_+SINEAluAluSz
CAediting_457452chr6_5719114_+SINEAluAluJb
CAediting_457453chr6_5719125_+SINEAluAluJb
CAediting_457454chr6_5719127_+SINEAluAluJb
CAediting_457455chr6_5719128_+SINEAluAluJb
CAediting_457456chr6_5719136_+SINEAluAluJb
CAediting_457457chr6_5719144_+SINEAluAluJb
CAediting_457458chr6_5719150_+SINEAluAluJb
CAediting_457459chr6_5719154_+SINEAluAluJb
CAediting_457460chr6_5719155_+SINEAluAluJb
CAediting_457461chr6_5719168_+SINEAluAluJb
CAediting_457462chr6_5719173_+SINEAluAluJb
CAediting_457463chr6_5719176_+SINEAluAluJb
CAediting_457464chr6_5719181_+SINEAluAluJb
CAediting_457465chr6_5719182_+SINEAluAluJb
CAediting_457466chr6_5719187_+SINEAluAluJb
CAediting_457467chr6_5719197_+SINEAluAluJb
CAediting_457468chr6_5719205_+SINEAluAluJb
CAediting_457469chr6_5719218_+SINEAluAluJb
CAediting_457470chr6_5719225_+SINEAluAluJb
CAediting_457471chr6_5719231_+SINEAluAluJb
CAediting_457472chr6_5719232_+SINEAluAluJb
CAediting_457473chr6_5719233_+SINEAluAluJb
CAediting_457474chr6_5719236_+SINEAluAluJb
CAediting_457475chr6_5719256_+SINEAluAluJb
CAediting_457476chr6_5719272_+SINEAluAluJb
CAediting_457477chr6_5719279_+SINEAluAluJb
CAediting_457478chr6_5719285_+SINEAluAluJb
CAediting_457479chr6_5719292_+SINEAluAluJb
CAediting_457480chr6_5719321_+SINEAluAluJb
CAediting_457481chr6_5719339_+SINEAluAluJb
CAediting_457482chr6_5719345_+SINEAluAluJb
CAediting_457483chr6_5719347_+SINEAluAluJb
CAediting_457484chr6_5720774_+SINEAluAluJr
CAediting_457485chr6_5738090_+SINEAluAluJr
CAediting_457486chr6_5739267_+SINEAluFLAM_C

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RNA A-to-I editing events in the alternative splicing sites for FARS2

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000145982.10.FARS2.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000145982.10.FARS2.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for FARS2

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for FARS2

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for FARS2

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for FARS2

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for FARS2

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
STADCAediting_457480chr6_5719321_+..0.02620756727332150.311238607495391..

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Relation with cancer stages for FARS2

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
STADpathologic_stageCAediting_457480chr6_5719321_+0.01079140923087970.354113673002924

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Relation with survival for FARS2

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for FARS2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
FARS2O95363DB00120PhenylalaninePhenylalanine--tRNA ligase, mitochondrial SmallMoleculeDrugapproved|investigational|nutraceutical

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RelatedDiseases for FARS2

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
FARS2C0023264Leigh Disease7CLINGEN
FARS2C1838951LEIGH SYNDROME DUE TO MITOCHONDRIAL COMPLEX I DEFICIENCY7CLINGEN
FARS2C1850597Leigh Syndrome Due To Mitochondrial Complex II Deficiency7CLINGEN
FARS2C1850598Leigh Syndrome due to Mitochondrial Complex III Deficiency7CLINGEN
FARS2C1850599Leigh Syndrome due to Mitochondrial Complex IV Deficiency7CLINGEN
FARS2C1850600Leigh Syndrome due to Mitochondrial Complex V Deficiency7CLINGEN
FARS2C2931891Necrotizing encephalopathy, infantile subacute, of Leigh7CLINGEN
FARS2C3554168COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 144CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
FARS2C4310750SPASTIC PARAPLEGIA 77, AUTOSOMAL RECESSIVE3CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT