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Editing gene: RN7SL737P (CAeditome ID:106481123)

Gene summary for RN7SL737P

Gene summary

Gene information	Gene symbol	RN7SL737P
	Gene ID	106481123
	Gene name	RNA, 7SL, cytoplasmic 737, pseudogene
	Synonyms	-
	Cytomap	12q22
	Type of gene	pseudo
	Description	-
	Modification date	20210518
	UniProtAcc	.
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for RN7SL737P

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000243015.2

RNA A-to-I editing events in Cancer.

CAediting_913558(93509490, +), CAediting_913559(93509496, +), CAediting_913560(93509502, +), CAediting_913561(93509512, +), CAediting_913562(93509514, +), CAediting_913563(93509522, +), CAediting_913564(93509526, +), CAediting_913565(93509535, +), CAediting_913566(93509537, +), CAediting_913567(93509539, +), CAediting_913568(93509542, +), CAediting_913569(93509553, +), CAediting_913570(93509558, +), CAediting_913571(93509560, +), CAediting_913572(93509561, +), CAediting_913573(93509574, +), CAediting_913574(93509591, +), CAediting_913575(93509604, +), CAediting_913576(93509605, +), CAediting_913577(93509610, +), CAediting_913578(93509704, +), CAediting_913579(93509725, +), CAediting_913580(93509729, +), CAediting_913581(93509753, +), CAediting_913582(93509765, +),

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RNA editing positional annotations for RN7SL737P using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_913558	chr12_93509490_+	ncRNA_exonic
CAediting_913559	chr12_93509496_+	ncRNA_exonic
CAediting_913560	chr12_93509502_+	ncRNA_exonic
CAediting_913561	chr12_93509512_+	ncRNA_exonic
CAediting_913562	chr12_93509514_+	ncRNA_exonic
CAediting_913563	chr12_93509522_+	ncRNA_exonic
CAediting_913564	chr12_93509526_+	ncRNA_exonic
CAediting_913565	chr12_93509535_+	ncRNA_exonic
CAediting_913566	chr12_93509537_+	ncRNA_exonic
CAediting_913567	chr12_93509539_+	ncRNA_exonic
CAediting_913568	chr12_93509542_+	ncRNA_exonic
CAediting_913569	chr12_93509553_+	ncRNA_exonic
CAediting_913570	chr12_93509558_+	ncRNA_exonic
CAediting_913571	chr12_93509560_+	ncRNA_exonic
CAediting_913572	chr12_93509561_+	ncRNA_exonic
CAediting_913573	chr12_93509574_+	ncRNA_exonic
CAediting_913574	chr12_93509591_+	ncRNA_exonic
CAediting_913575	chr12_93509604_+	ncRNA_exonic
CAediting_913576	chr12_93509605_+	ncRNA_exonic
CAediting_913577	chr12_93509610_+	ncRNA_exonic
CAediting_913578	chr12_93509704_+	ncRNA_exonic
CAediting_913579	chr12_93509725_+	ncRNA_exonic
CAediting_913580	chr12_93509729_+	ncRNA_exonic
CAediting_913581	chr12_93509753_+	ncRNA_exonic
CAediting_913582	chr12_93509765_+	ncRNA_exonic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_913558	chr12_93509490_+	srpRNA	srpRNA	7SLRNA
CAediting_913559	chr12_93509496_+	srpRNA	srpRNA	7SLRNA
CAediting_913560	chr12_93509502_+	srpRNA	srpRNA	7SLRNA
CAediting_913561	chr12_93509512_+	srpRNA	srpRNA	7SLRNA
CAediting_913562	chr12_93509514_+	srpRNA	srpRNA	7SLRNA
CAediting_913563	chr12_93509522_+	srpRNA	srpRNA	7SLRNA
CAediting_913564	chr12_93509526_+	srpRNA	srpRNA	7SLRNA
CAediting_913565	chr12_93509535_+	srpRNA	srpRNA	7SLRNA
CAediting_913566	chr12_93509537_+	srpRNA	srpRNA	7SLRNA
CAediting_913567	chr12_93509539_+	srpRNA	srpRNA	7SLRNA
CAediting_913568	chr12_93509542_+	srpRNA	srpRNA	7SLRNA
CAediting_913569	chr12_93509553_+	srpRNA	srpRNA	7SLRNA
CAediting_913570	chr12_93509558_+	srpRNA	srpRNA	7SLRNA
CAediting_913571	chr12_93509560_+	srpRNA	srpRNA	7SLRNA
CAediting_913572	chr12_93509561_+	srpRNA	srpRNA	7SLRNA
CAediting_913573	chr12_93509574_+	srpRNA	srpRNA	7SLRNA
CAediting_913574	chr12_93509591_+	srpRNA	srpRNA	7SLRNA
CAediting_913575	chr12_93509604_+	srpRNA	srpRNA	7SLRNA
CAediting_913576	chr12_93509605_+	srpRNA	srpRNA	7SLRNA
CAediting_913577	chr12_93509610_+	srpRNA	srpRNA	7SLRNA
CAediting_913578	chr12_93509704_+	srpRNA	srpRNA	7SLRNA
CAediting_913579	chr12_93509725_+	srpRNA	srpRNA	7SLRNA
CAediting_913580	chr12_93509729_+	srpRNA	srpRNA	7SLRNA
CAediting_913581	chr12_93509753_+	srpRNA	srpRNA	7SLRNA
CAediting_913582	chr12_93509765_+	srpRNA	srpRNA	7SLRNA

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RNA A-to-I editing events in the alternative splicing sites for RN7SL737P

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000243015.2.RN7SL737P.

Correlation between RNA A-to-I editing and PSI for ENSG00000243015.2.RN7SL737P.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RN7SL737P

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for RN7SL737P

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for RN7SL737P

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for RN7SL737P

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for RN7SL737P

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for RN7SL737P

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
ESCA	pathologic_stage	CAediting_913564	chr12_93509526_+	0.01544491718919	0.23924670087887
KIRP	clinical_stage	CAediting_913564	chr12_93509526_+	0.0463301270290337	0.199736062485545

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Relation with survival for RN7SL737P

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
OV	CAediting_913564	chr12_93509526_+	0.0462493328037771	0.00371191	7.10173
SKCM	CAediting_913564	chr12_93509526_+	0.0271628288227583	0.0399878	22.3587

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RelatedDrugs for RN7SL737P

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for RN7SL737P

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene