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Center for Computational Systems Medicine
Soverview

Gene summary

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RNA A-to-I events

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Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

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Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

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Relation with ADAR

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Relation with cancer stages

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Relation with survival state

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Related drugs with this gene

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Related diseases with this gene

Editing gene: RN7SL608P (CAeditome ID:106480521)

Gene summary for RN7SL608P

check button Gene summary
Gene informationGene symbol

RN7SL608P

Gene ID

106480521

Gene nameRNA, 7SL, cytoplasmic 608, pseudogene
Synonyms-
Cytomap

17p13.3

Type of genepseudo
Description-
Modification date20210518
UniProtAcc

.

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for RN7SL608P

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000239884.3
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_1154055(2680963, +), CAediting_1154056(2680977, +), CAediting_1154057(2681004, +), CAediting_1154058(2681009, +), CAediting_1154059(2681023, +), CAediting_1154060(2681025, +), CAediting_1154061(2681044, +), CAediting_1154062(2681215, +),

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RNA editing positional annotations for RN7SL608P using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1154055chr17_2680963_+ncRNA_exonic
CAediting_1154056chr17_2680977_+ncRNA_exonic
CAediting_1154057chr17_2681004_+ncRNA_exonic
CAediting_1154058chr17_2681009_+ncRNA_exonic
CAediting_1154059chr17_2681023_+ncRNA_exonic
CAediting_1154060chr17_2681025_+ncRNA_exonic
CAediting_1154061chr17_2681044_+ncRNA_exonic
CAediting_1154062chr17_2681215_+ncRNA_exonic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1154055chr17_2680963_+srpRNAsrpRNA7SLRNA
CAediting_1154056chr17_2680977_+srpRNAsrpRNA7SLRNA
CAediting_1154057chr17_2681004_+srpRNAsrpRNA7SLRNA
CAediting_1154058chr17_2681009_+srpRNAsrpRNA7SLRNA
CAediting_1154059chr17_2681023_+srpRNAsrpRNA7SLRNA
CAediting_1154060chr17_2681025_+srpRNAsrpRNA7SLRNA
CAediting_1154061chr17_2681044_+srpRNAsrpRNA7SLRNA
CAediting_1154062chr17_2681215_+srpRNAsrpRNA7SLRNA

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RNA A-to-I editing events in the alternative splicing sites for RN7SL608P

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000239884.3.RN7SL608P.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000239884.3.RN7SL608P.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RN7SL608P

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for RN7SL608P

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for RN7SL608P

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for RN7SL608P

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for RN7SL608P

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
LUSCCAediting_1154058chr17_2681009_+....0.005797635369145490.357978339760744

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Relation with cancer stages for RN7SL608P

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for RN7SL608P

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for RN7SL608P

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for RN7SL608P

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource