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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: HEXIM1 (CAeditome ID:10614) |
Gene summary for HEXIM1 |
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Gene information | Gene symbol | HEXIM1 | Gene ID | 10614 |
Gene name | HEXIM P-TEFb complex subunit 1 | |
Synonyms | CLP1|EDG1|HIS1|MAQ1 | |
Cytomap | 17q21.31 | |
Type of gene | protein-coding | |
Description | protein HEXIM1HMBA-induciblecardiac lineage protein 1estrogen down-regulated gene 1 proteinhexamethylene bis-acetamide inducible 1hexamethylene bis-acetamide-inducible protein 1hexamethylene bisacetamide inducible 1hexamethylene bisacetamide-induci | |
Modification date | 20210518 | |
UniProtAcc | O94992 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
HEXIM1 | GO:0004860 | Protein HEXIM1 | 28431135 |
HEXIM1 | GO:0004861 | Protein HEXIM1 | 14580347 |
HEXIM1 | GO:0017069 | Protein HEXIM1 | 14580347 |
HEXIM1 | GO:0097322 | Protein HEXIM1 | 12832472 |
HEXIM1 | GO:0097322 | Protein HEXIM1 | 18249148 |
HEXIM1 | GO:0097322 | Protein HEXIM1 | 18483487 |
HEXIM1 | GO:0097322 | Protein HEXIM1 | 19883659 |
HEXIM1 | GO:0097322 | Protein HEXIM1 | 28431135 |
HEXIM1 | GO:0106140 | Protein HEXIM1 | 18249148 |
HEXIM1 | GO:0106140 | Protein HEXIM1 | 18483487 |
HEXIM1 | GO:0106140 | Protein HEXIM1 | 28431135 |
HEXIM1 | GO:0000122 | Protein HEXIM1 | 14580347 |
HEXIM1 | GO:0002218 | Protein HEXIM1 | 28712728 |
HEXIM1 | GO:0045736 | Protein HEXIM1 | 14580347 |
HEXIM1 | GO:0045892 | Protein HEXIM1 | 14580347 |
HEXIM1 | GO:0005634 | Protein HEXIM1 | 12581153 |
HEXIM1 | GO:0005634 | Protein HEXIM1 | 28712728 |
HEXIM1 | GO:0005654 | Protein HEXIM1 | 0000052 |
HEXIM1 | GO:0005737 | Protein HEXIM1 | 12581153 |
HEXIM1 | GO:0043231 | Protein HEXIM1 | 0000052 |
HEXIM1 | GO:0120259 | Protein HEXIM1 | 18249148 |
HEXIM1 | GO:0120259 | Protein HEXIM1 | 18483487 |
HEXIM1 | GO:0120259 | Protein HEXIM1 | 28431135 |
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RNA A-to-I events for HEXIM1 |
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CAediting_1204148(45149672, +), CAediting_1204149(45149693, +), CAediting_1204150(45150055, +), CAediting_1204151(45150107, +), |
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RNA editing positional annotations for HEXIM1 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
CAediting_1204148 | chr17_45149672_+ | nonsynonymous SNV | ENST00000332499.3 | c.A482G | p.K161R | T | D | N |
CAediting_1204150 | chr17_45150055_+ | nonsynonymous SNV | ENST00000332499.3 | c.A865G | p.K289E | D | B | N |
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CAeditome ID | Position | Variant type |
CAediting_1204148 | chr17_45149672_+ | exonic |
CAediting_1204149 | chr17_45149693_+ | exonic |
CAediting_1204150 | chr17_45150055_+ | exonic |
CAediting_1204151 | chr17_45150107_+ | exonic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
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RNA A-to-I editing events in the alternative splicing sites for HEXIM1 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for HEXIM1 |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for HEXIM1 |
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The effects of the RNA editing to the miRNA binding sites for HEXIM1 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for HEXIM1 |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for HEXIM1 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for HEXIM1 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for HEXIM1 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for HEXIM1 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for HEXIM1 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
HEXIM1 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |