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Editing gene: ERVK3-1 (CAeditome ID:105372481)

Gene summary for ERVK3-1

Gene summary

Gene information	Gene symbol	ERVK3-1
	Gene ID	105372481
	Gene name	endogenous retrovirus group K3 member 1
	Synonyms	-
	Cytomap	19q13.43
	Type of gene	ncRNA
	Description	HERV-K(HML6-1)
	Modification date	20210518
	UniProtAcc	.
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for ERVK3-1

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000142396.9

RNA A-to-I editing events in Cancer.

CAediting_1397412(58313306, +), CAediting_1397413(58313318, +), CAediting_1397414(58313351, +), CAediting_1397415(58313361, +), CAediting_1397416(58313387, +), CAediting_1397417(58313403, +), CAediting_1397418(58313415, +), CAediting_1397419(58313425, +), CAediting_1397420(58313431, +), CAediting_1397421(58313467, +), CAediting_1397422(58313473, +), CAediting_1397423(58313474, +), CAediting_1397424(58313476, +), CAediting_1397425(58313479, +), CAediting_1397426(58313480, +), CAediting_1397427(58313485, +), CAediting_1397428(58313490, +), CAediting_1397429(58313502, +), CAediting_1397430(58313515, +), CAediting_1397431(58313522, +), CAediting_1397432(58313530, +), CAediting_1397433(58313534, +), CAediting_1397434(58313551, +), CAediting_1397435(58313552, +), CAediting_1397436(58313553, +), CAediting_1397437(58313565, +), CAediting_1397438(58313567, +), CAediting_1397439(58313574, +), CAediting_1397440(58313578, +), CAediting_1397441(58313629, +), CAediting_1397442(58314191, +), CAediting_1397443(58314299, +), CAediting_1397444(58314302, +), CAediting_1397445(58314329, +), CAediting_1397446(58314332, +), CAediting_1397447(58314333, +), CAediting_1397448(58314363, +), CAediting_1397449(58314371, +), CAediting_1397450(58314380, +), CAediting_1397451(58314388, +), CAediting_1397452(58314398, +), CAediting_1397453(58314402, +), CAediting_1397454(58314407, +), CAediting_1397455(58314417, +), CAediting_1397456(58314418, +), CAediting_1397457(58314439, +), CAediting_1397458(58314440, +), CAediting_1397459(58314441, +), CAediting_1397460(58314443, +), CAediting_1397461(58314447, +), CAediting_1397462(58314448, +), CAediting_1397463(58314449, +), CAediting_1397464(58314466, +), CAediting_1397465(58314500, +), CAediting_1397466(58314506, +), CAediting_1397467(58314512, +), CAediting_1397468(58314516, +), CAediting_1397469(58314517, +), CAediting_1397470(58314520, +), CAediting_1397471(58314542, +), CAediting_1397472(58314548, +), CAediting_1397473(58314555, +), CAediting_1397474(58314559, +), CAediting_1397475(58314568, +), CAediting_1397476(58314572, +), CAediting_1397477(58314577, +), CAediting_1397478(58314579, +),

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RNA editing positional annotations for ERVK3-1 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1397412	chr19_58313306_+	ncRNA_intronic
CAediting_1397413	chr19_58313318_+	ncRNA_intronic
CAediting_1397414	chr19_58313351_+	ncRNA_intronic
CAediting_1397415	chr19_58313361_+	ncRNA_intronic
CAediting_1397416	chr19_58313387_+	ncRNA_intronic
CAediting_1397417	chr19_58313403_+	ncRNA_intronic
CAediting_1397418	chr19_58313415_+	ncRNA_intronic
CAediting_1397419	chr19_58313425_+	ncRNA_intronic
CAediting_1397420	chr19_58313431_+	ncRNA_intronic
CAediting_1397421	chr19_58313467_+	ncRNA_intronic
CAediting_1397422	chr19_58313473_+	ncRNA_intronic
CAediting_1397423	chr19_58313474_+	ncRNA_intronic
CAediting_1397424	chr19_58313476_+	ncRNA_intronic
CAediting_1397425	chr19_58313479_+	ncRNA_intronic
CAediting_1397426	chr19_58313480_+	ncRNA_intronic
CAediting_1397427	chr19_58313485_+	ncRNA_intronic
CAediting_1397428	chr19_58313490_+	ncRNA_intronic
CAediting_1397429	chr19_58313502_+	ncRNA_intronic
CAediting_1397430	chr19_58313515_+	ncRNA_intronic
CAediting_1397431	chr19_58313522_+	ncRNA_intronic
CAediting_1397432	chr19_58313530_+	ncRNA_intronic
CAediting_1397433	chr19_58313534_+	ncRNA_intronic
CAediting_1397434	chr19_58313551_+	ncRNA_intronic
CAediting_1397435	chr19_58313552_+	ncRNA_intronic
CAediting_1397436	chr19_58313553_+	ncRNA_intronic
CAediting_1397437	chr19_58313565_+	ncRNA_intronic
CAediting_1397438	chr19_58313567_+	ncRNA_intronic
CAediting_1397439	chr19_58313574_+	ncRNA_intronic
CAediting_1397440	chr19_58313578_+	ncRNA_intronic
CAediting_1397441	chr19_58313629_+	ncRNA_intronic
CAediting_1397442	chr19_58314191_+	ncRNA_intronic
CAediting_1397443	chr19_58314299_+	ncRNA_intronic
CAediting_1397444	chr19_58314302_+	ncRNA_intronic
CAediting_1397445	chr19_58314329_+	ncRNA_intronic
CAediting_1397446	chr19_58314332_+	ncRNA_intronic
CAediting_1397447	chr19_58314333_+	ncRNA_intronic
CAediting_1397448	chr19_58314363_+	ncRNA_intronic
CAediting_1397449	chr19_58314371_+	ncRNA_intronic
CAediting_1397450	chr19_58314380_+	ncRNA_intronic
CAediting_1397451	chr19_58314388_+	ncRNA_intronic
CAediting_1397452	chr19_58314398_+	ncRNA_intronic
CAediting_1397453	chr19_58314402_+	ncRNA_intronic
CAediting_1397454	chr19_58314407_+	ncRNA_intronic
CAediting_1397455	chr19_58314417_+	ncRNA_intronic
CAediting_1397456	chr19_58314418_+	ncRNA_intronic
CAediting_1397457	chr19_58314439_+	ncRNA_intronic
CAediting_1397458	chr19_58314440_+	ncRNA_intronic
CAediting_1397459	chr19_58314441_+	ncRNA_intronic
CAediting_1397460	chr19_58314443_+	ncRNA_intronic
CAediting_1397461	chr19_58314447_+	ncRNA_intronic
CAediting_1397462	chr19_58314448_+	ncRNA_intronic
CAediting_1397463	chr19_58314449_+	ncRNA_intronic
CAediting_1397464	chr19_58314466_+	ncRNA_intronic
CAediting_1397465	chr19_58314500_+	ncRNA_intronic
CAediting_1397466	chr19_58314506_+	ncRNA_intronic
CAediting_1397467	chr19_58314512_+	ncRNA_intronic
CAediting_1397468	chr19_58314516_+	ncRNA_intronic
CAediting_1397469	chr19_58314517_+	ncRNA_intronic
CAediting_1397470	chr19_58314520_+	ncRNA_intronic
CAediting_1397471	chr19_58314542_+	ncRNA_intronic
CAediting_1397472	chr19_58314548_+	ncRNA_intronic
CAediting_1397473	chr19_58314555_+	ncRNA_intronic
CAediting_1397474	chr19_58314559_+	ncRNA_intronic
CAediting_1397475	chr19_58314568_+	ncRNA_intronic
CAediting_1397476	chr19_58314572_+	ncRNA_intronic
CAediting_1397477	chr19_58314577_+	ncRNA_intronic
CAediting_1397478	chr19_58314579_+	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1397412	chr19_58313306_+	SINE	Alu	AluSg7
CAediting_1397413	chr19_58313318_+	SINE	Alu	AluSg7
CAediting_1397414	chr19_58313351_+	SINE	Alu	AluSg7
CAediting_1397415	chr19_58313361_+	SINE	Alu	AluSg7
CAediting_1397416	chr19_58313387_+	SINE	Alu	AluSg7
CAediting_1397417	chr19_58313403_+	SINE	Alu	AluSg7
CAediting_1397418	chr19_58313415_+	SINE	Alu	AluSg7
CAediting_1397419	chr19_58313425_+	SINE	Alu	AluSg7
CAediting_1397420	chr19_58313431_+	SINE	Alu	AluSg7
CAediting_1397421	chr19_58313467_+	SINE	Alu	AluSg7
CAediting_1397422	chr19_58313473_+	SINE	Alu	AluSg7
CAediting_1397423	chr19_58313474_+	SINE	Alu	AluSg7
CAediting_1397424	chr19_58313476_+	SINE	Alu	AluSg7
CAediting_1397425	chr19_58313479_+	SINE	Alu	AluSg7
CAediting_1397426	chr19_58313480_+	SINE	Alu	AluSg7
CAediting_1397427	chr19_58313485_+	SINE	Alu	AluSg7
CAediting_1397428	chr19_58313490_+	SINE	Alu	AluSg7
CAediting_1397429	chr19_58313502_+	SINE	Alu	AluSg7
CAediting_1397430	chr19_58313515_+	SINE	Alu	AluSg7
CAediting_1397431	chr19_58313522_+	SINE	Alu	AluSg7
CAediting_1397432	chr19_58313530_+	SINE	Alu	AluSg7
CAediting_1397433	chr19_58313534_+	SINE	Alu	AluSg7
CAediting_1397434	chr19_58313551_+	SINE	Alu	AluSg7
CAediting_1397435	chr19_58313552_+	SINE	Alu	AluSg7
CAediting_1397436	chr19_58313553_+	SINE	Alu	AluSg7
CAediting_1397437	chr19_58313565_+	SINE	Alu	AluSg7
CAediting_1397438	chr19_58313567_+	SINE	Alu	AluSg7
CAediting_1397439	chr19_58313574_+	SINE	Alu	AluSg7
CAediting_1397440	chr19_58313578_+	SINE	Alu	AluSg7
CAediting_1397441	chr19_58313629_+	LTR	ERVK	HERVK3-int
CAediting_1397442	chr19_58314191_+	LTR	ERVK	HERVK3-int
CAediting_1397443	chr19_58314299_+	LTR	ERVK	HERVK3-int
CAediting_1397444	chr19_58314302_+	LTR	ERVK	HERVK3-int
CAediting_1397445	chr19_58314329_+	LTR	ERVK	HERVK3-int
CAediting_1397446	chr19_58314332_+	LTR	ERVK	HERVK3-int
CAediting_1397447	chr19_58314333_+	LTR	ERVK	HERVK3-int
CAediting_1397448	chr19_58314363_+	SINE	Alu	AluY
CAediting_1397449	chr19_58314371_+	SINE	Alu	AluY
CAediting_1397450	chr19_58314380_+	SINE	Alu	AluY
CAediting_1397451	chr19_58314388_+	SINE	Alu	AluY
CAediting_1397452	chr19_58314398_+	SINE	Alu	AluY
CAediting_1397453	chr19_58314402_+	SINE	Alu	AluY
CAediting_1397454	chr19_58314407_+	SINE	Alu	AluY
CAediting_1397455	chr19_58314417_+	SINE	Alu	AluY
CAediting_1397456	chr19_58314418_+	SINE	Alu	AluY
CAediting_1397457	chr19_58314439_+	SINE	Alu	AluY
CAediting_1397458	chr19_58314440_+	SINE	Alu	AluY
CAediting_1397459	chr19_58314441_+	SINE	Alu	AluY
CAediting_1397460	chr19_58314443_+	SINE	Alu	AluY
CAediting_1397461	chr19_58314447_+	SINE	Alu	AluY
CAediting_1397462	chr19_58314448_+	SINE	Alu	AluY
CAediting_1397463	chr19_58314449_+	SINE	Alu	AluY
CAediting_1397464	chr19_58314466_+	SINE	Alu	AluY
CAediting_1397465	chr19_58314500_+	SINE	Alu	AluY
CAediting_1397466	chr19_58314506_+	SINE	Alu	AluY
CAediting_1397467	chr19_58314512_+	SINE	Alu	AluY
CAediting_1397468	chr19_58314516_+	SINE	Alu	AluY
CAediting_1397469	chr19_58314517_+	SINE	Alu	AluY
CAediting_1397470	chr19_58314520_+	SINE	Alu	AluY
CAediting_1397471	chr19_58314542_+	SINE	Alu	AluY
CAediting_1397472	chr19_58314548_+	SINE	Alu	AluY
CAediting_1397473	chr19_58314555_+	SINE	Alu	AluY
CAediting_1397474	chr19_58314559_+	SINE	Alu	AluY
CAediting_1397475	chr19_58314568_+	SINE	Alu	AluY
CAediting_1397476	chr19_58314572_+	SINE	Alu	AluY
CAediting_1397477	chr19_58314577_+	SINE	Alu	AluY
CAediting_1397478	chr19_58314579_+	SINE	Alu	AluY

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RNA A-to-I editing events in the alternative splicing sites for ERVK3-1

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000142396.9.ERVK3-1.

Correlation between RNA A-to-I editing and PSI for ENSG00000142396.9.ERVK3-1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ERVK3-1

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for ERVK3-1

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for ERVK3-1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ERVK3-1

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for ERVK3-1

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
OV	CAediting_1397452	chr19_58314398_+	0.00129640883965325	0.29897991420587	.	.	.	.

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Relation with cancer stages for ERVK3-1

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for ERVK3-1

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for ERVK3-1

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for ERVK3-1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene